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--- |
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license: mit |
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tags: |
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- alphafold |
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- clarus |
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- biology |
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- structure |
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- evaluation |
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- safety |
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--- |
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AlphaFold Misinterpretation Classifier (AMC) v0.1 |
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Purpose |
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Help models spot when AlphaFold outputs are used to make claims that go beyond their scope. |
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Teach restraint. |
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Promote correct boundaries around structural interpretation. |
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Columns |
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- claim |
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- misinterpretation_type |
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- reason_hint |
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- action |
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misinterpretation_type examples |
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- function_from_structure: assuming activity from fold |
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- binding_assertion: assuming ligand interaction |
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- metric_confusion: misreading confidence or aligned error |
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- state_fixation: treating one conformation as the only state |
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- taxonomy_jump: treating confidence as family evidence |
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action |
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- refuse: decline and point out the jump |
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- request_context: ask for missing conditions |
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- answer_with_correction: correct logic without overreach |
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Use |
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- evaluation on biomedical hallucination |
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- model alignment training around biological scope limits |
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- developer sanity checks for RAG systems using AlphaFold output |
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Boundaries |
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No lab instructions. |
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No sequence design. |
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No optimization paths. |
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All statements focus on conceptual fit, not engineering. |
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