Datasets:

ClarusC64
/

clinical-etiological-basin-identification-v0.1

id stringclasses 10 values	syndrome_label stringclasses 4 values	precipitating_event stringclasses 5 values	illness_duration_months int64 10 84	immune_features stringclasses 9 values	metabolic_features stringclasses 10 values	autonomic_features stringclasses 8 values	neurocognitive_features stringclasses 10 values	symptom_dynamics stringclasses 9 values	comorbidity_cluster stringclasses 9 values	basin_id stringclasses 5 values	basin_stability_score_0_100 int64 70 90	defining_state_features_top5 stringclasses 10 values	basin_evidence stringclasses 10 values	constraints stringclasses 1 value	gold_checklist stringclasses 1 value
EBM-001	Long-COVID	viral_triggered	18	IL6 high; CRP mild; ferritin high	lactate high post-exertion; low VO2	POTS pattern; HR spike on standing	brain fog; word finding	PEM 24-48h; relapsing	asthma; anxiety	basin_A_inflammatory_autonomic	82	POTS; IL6-high; PEM; HR-stand-spike; post-exertion lactate	Autonomic instability plus inflammatory tone dominates despite mixed symptoms	Under 220 words.	1 basin
EBM-002	ME/CFS	stress_triggered	60	CRP normal; cytokines mixed	low ATP proxy; high fatigue index	orthostatic intolerance	brain fog; sensory sensitivity	PEM 48h; chronic plateau	IBS	basin_B_mito_metabolic_fatigue	88	PEM; chronic plateau; low energy proxy; orthostatic intolerance; activity crash	Metabolic fatigue basin with strong stability across years	Under 220 words.	1 basin
EBM-003	Autoimmune cluster	mixed_or_unknown	36	ANA positive; ESR high	normal glucose; weight loss	variable BP; cold intolerance	cognitive slowing	waxing flares; joint pain	thyroiditis	basin_E_autoimmune_multisystem	80	ANA+; ESR-high; flares; multisystem; joint pain	Autoimmune multi-system basin with flare topology	Under 220 words.	1 basin
EBM-004	Long-COVID	viral_triggered	12	tryptase borderline; eos high	normal labs	tachycardia episodes	headache	food-trigger flares; episodic	urticaria	basin_D_mast_cell_histamine_like	74	food-trigger flares; urticaria; eos-high; episodic tachy; histamine pattern	Trigger-linked episodic basin with mast-cell features	Under 220 words.	1 basin
EBM-005	ME/CFS	toxic_exposure	30	CRP normal	exercise intolerance; lactate high	POTS mild	brain fog moderate	PEM 24-48h; relapsing	migraines	basin_B_mito_metabolic_fatigue	78	exercise intolerance; PEM; lactate; fatigue index; relapse pattern	Metabolic-fatigue basin despite different trigger	Under 220 words.	1 basin
EBM-006	Long-COVID	viral_triggered	10	CRP high; IL6 high	glucose variability	orthostatic intolerance	brain fog severe	relapsing; inflammatory surges	asthma	basin_A_inflammatory_autonomic	76	IL6-high; CRP-high; orthostatic; relapse; autonomic swings	Inflammation plus autonomic dysregulation forms stable basin	Under 220 words.	1 basin
EBM-007	Autoimmune cluster	iatrogenic	24	ESR high; complement low	weight loss	variable HR	cognitive issues	flare after taper; partial remissions	rash	basin_E_autoimmune_multisystem	79	complement-low; ESR-high; flare after taper; rash; multi-system	Immune system state dominates with medication-linked dynamics	Under 220 words.	1 basin
EBM-008	Long-COVID	stress_triggered	20	cytokines mixed	normal lactate	POTS strong	attention issues	crashes after activity; relapsing	IBS	basin_A_inflammatory_autonomic	70	POTS; activity crash; attention; orthostatic; relapse	Autonomic basin even with weak immune markers	Under 220 words.	1 basin
EBM-009	ME/CFS	viral_triggered	84	CRP normal	low energy proxy	orthostatic intolerance	sensory sensitivity	stable plateau; PEM 48h	IBS; migraine	basin_B_mito_metabolic_fatigue	90	PEM 48h; stable plateau; sensory sensitivity; orthostatic; fatigue	Highly stable metabolic-fatigue basin over years	Under 220 words.	1 basin
EBM-010	Neuroimmune syndrome	mixed_or_unknown	22	microglial proxy high; cytokines mixed	normal basic labs	mild orthostatic	cognitive impairment; headache	waves of cognitive collapse	depression	basin_C_neuroimmune_cognitive	73	cognitive collapse waves; headache; neuroimmune proxy; attention failure; fluctuating	Primary neurocognitive basin with immune tone	Under 220 words.	1 basin

What this dataset tests

Whether a model can identify the stable illness basin
from multi-system features, independent of trigger.

Required outputs

basin_id
basin_stability_score_0_100
defining_state_features_top5

Basin labels

basin_A_inflammatory_autonomic
basin_B_mito_metabolic_fatigue
basin_C_neuroimmune_cognitive
basin_D_mast_cell_histamine_like
basin_E_autoimmune_multisystem

Typical failures

using precipitating event as the primary classifier
listing symptoms without identifying the basin state
failing to name the top defining features

Suggested prompt wrapper

System

You assign an illness basin from multi-system features.

User

Immune
{immune_features}

Metabolic
{metabolic_features}

Autonomic
{autonomic_features}

Neurocognitive
{neurocognitive_features}

Dynamics
{symptom_dynamics}

Return

basin id
stability score
top 5 defining features
one sentence evidence

Citation

ClarusC64 dataset family

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