Datasets:

ClarusC64
/

clinical-etiological-pathway-divergence-mapping-v0.1

id stringclasses 10 values	basin_id stringclasses 5 values	syndrome_label stringclasses 6 values	precipitating_event stringclasses 5 values	early_phase_features stringclasses 10 values	established_basin_features stringclasses 10 values	entry_signature_top5 stringclasses 10 values	pathway_type stringclasses 5 values	distance_from_basin_core_0_100 int64 14 35	pathway_evidence stringclasses 10 values	constraints stringclasses 1 value	gold_checklist stringclasses 8 values
EPDM-001	basin_A_inflammatory_autonomic	Long-COVID	viral_triggered	acute fever; anosmia; high IL6 early; tachycardia onset week2	POTS; IL6-high; PEM; post-exertion lactate	anosmia; acute fever; IL6 spike; week2 tachy; early exertion crash	viral_triggered	18	Classic viral entry with immune surge then autonomic basin lock-in	Under 220 words.	1 viral
EPDM-002	basin_A_inflammatory_autonomic	Long-COVID-like	stress_triggered	major life stress; insomnia; panic episodes; HR spikes on standing	POTS; PEM; relapse waves	insomnia onset; panic episodes; HR stand spike; cortisol-like pattern; early crash	stress_triggered	28	Autonomic basin reached via stress and sleep collapse without clear viral phase	Under 220 words.	1 stress
EPDM-003	basin_B_mito_metabolic_fatigue	ME/CFS	viral_triggered	mono-like illness; prolonged bedrest; early PEM	PEM 48h; plateau; low energy proxy	mono-like start; early PEM; exertion intolerance; prolonged recovery; plateau lock	viral_triggered	14	Viral entry converges toward metabolic-fatigue basin core	Under 220 words.	1 viral
EPDM-004	basin_B_mito_metabolic_fatigue	ME/CFS	toxic_exposure	solvent exposure; headaches; nausea; fatigue onset	PEM; exercise intolerance; lactate high	toxin exposure; headache cluster; nausea; early fatigue surge; exercise crash	toxic_exposure	30	Toxic entry converges to same metabolic basin but farther from core due to neurotox pattern	Under 220 words.	1 toxic
EPDM-005	basin_D_mast_cell_histamine_like	Long-COVID-like	viral_triggered	viral URI; rashes within 2 weeks; food sensitivity onset	episodic flares; urticaria; eos high	rash onset; food trigger; flushing; episodic tachy; antihistamine response	viral_triggered	22	Viral entry with mast-cell phenotype early	Under 220 words.	1 mast
EPDM-006	basin_D_mast_cell_histamine_like	idiopathic MCAS-like	mixed_or_unknown	years of episodic hives; stress-trigger flushing	episodic flares; food triggers; tachy episodes	long history hives; stress flushing; food trigger; episodic GI; antihistamine response	mixed_or_unknown	35	Same basin reached without single clear trigger; long pre-basin drift	Under 220 words.	1 unknown
EPDM-007	basin_E_autoimmune_multisystem	autoimmune cluster	iatrogenic	post-biologic taper; rebound inflammation; rash	ANA+; ESR high; flare topology	taper rebound; rash; ESR rise; joint pain onset; complement drop	iatrogenic	26	Medication perturbation initiates entry into autoimmune basin	Under 220 words.	1 iatro
EPDM-008	basin_E_autoimmune_multisystem	autoimmune cluster	mixed_or_unknown	slow onset; intermittent arthralgia; fatigue	ANA+; flares; multisystem	slow onset; arthralgia; fatigue; flare cycling; ANA conversion	mixed_or_unknown	20	Slow drift entry reaches autoimmune basin core without discrete trigger	Under 220 words.	1 drift
EPDM-009	basin_C_neuroimmune_cognitive	neuroimmune syndrome	viral_triggered	viral illness; early headache; cognitive dip week3	cognitive collapse waves; neuroimmune proxy high	early headache; week3 cognition dip; sleep disruption; sensory sensitivity; waves	viral_triggered	24	Viral entry with delayed neurocognitive collapse signature	Under 220 words.	1 neuro
EPDM-010	basin_C_neuroimmune_cognitive	neuroimmune syndrome	stress_triggered	burnout; chronic insomnia; attentional failures	cognitive waves; headache	burnout; insomnia; attention failure; sensory overload; episodic collapse	stress_triggered	32	Stress-driven entry signature yields same basin but weaker immune flare	Under 220 words.	1 stress

What this dataset tests

Whether a model can identify how different etiological pathways
enter the same stable illness basin.

Required outputs

pathway_type
entry_signature_top5
distance_from_basin_core_0_100

Pathway types

viral_triggered
stress_triggered
toxic_exposure
iatrogenic
mixed_or_unknown

Typical failures

using basin_id as a proxy for pathway
ignoring early phase features
outputting distance with no rationale

Suggested prompt wrapper

System

You map etiological pathway divergence into a shared basin.

User

Basin
{basin_id}

Early phase
{early_phase_features}

Established basin features
{established_basin_features}

Return

pathway type
top 5 entry signature features
distance from basin core
one sentence evidence

Citation

ClarusC64 dataset family

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