Datasets:

ClarusC64
/

cross-domain-invariant-structure-alignment-mapping-v0.1

id stringclasses 10 values	pair_id stringclasses 10 values	domain_a stringclasses 10 values	domain_b stringclasses 10 values	domain_a_phase_map stringclasses 10 values	domain_b_phase_map stringclasses 10 values	domain_a_failure_modes stringclasses 10 values	domain_b_failure_modes stringclasses 10 values	invariant_alignment_map stringclasses 10 values	mismatch_flags stringclasses 10 values	alignment_coherence_score_0_100 int64 70 86	alignment_evidence stringclasses 10 values	constraints stringclasses 1 value	gold_checklist stringclasses 1 value
ISAM-001	P-01	wound healing cascade	psychological trauma recovery	phase1 hemostasis minutes-hours; phase2 inflammation days; phase3 proliferation days-weeks; phase4 remodeling weeks-months	phase1 shock minutes-days; phase2 acute arousal days-weeks; phase3 meaning-making weeks-months; phase4 integration months-years	chronic inflammation; infection; hypertrophic scar; fibrosis	hyperarousal persistence; avoidance; intrusive memory; chronic dysregulation	A1 hemostasis aligns with B1 shock as immediate containment; A2 inflammation aligns with B2 arousal as mobilized defense; A3 proliferation aligns with B3 meaning-making as repair building; A4 remodeling aligns with B4 integration as long-term reorganization	mismatch if B2 lacks clear biomarker proxy; social context adds external drivers not present in A	86	Both are phase-ordered repair systems with early containment, mobilized defense, rebuilding, and long reorganization. Failure modes cluster as stuck activation and maladaptive remodeling.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-002	P-02	fibrosis prevention in tissue repair	post-trauma psychological scarring prevention	phase1 injury signaling; phase2 inflammatory amplification; phase3 fibroblast activation; phase4 matrix remodeling	phase1 threat encoding; phase2 arousal amplification; phase3 consolidation of narratives; phase4 long-term memory remodeling	excess TGF-beta signaling; myofibroblast persistence; stiff ECM	overconsolidation of threat; rigid identity narrative; persistent avoidance loops	A2 amplification aligns with B2 amplification; A3 fibroblast persistence aligns with B3 rigid consolidation; A4 matrix remodeling aligns with B4 memory remodeling	mismatch if B has no single pathway analogue; ethical limits on intervention differ	82	Both contain a risk of repair overshoot that hardens the system. The invariant is persistent activation that converts adaptive repair into rigid structure.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-003	P-03	sepsis trajectory stabilization	delirium prevention and recovery	phase1 infection trigger; phase2 systemic inflammation; phase3 organ support and recovery; phase4 immune reset	phase1 precipitant trigger; phase2 global dysregulation; phase3 stabilization and reorientation; phase4 cognitive reintegration	cytokine storm; microcirculatory failure; multi-organ dysfunction	sleep-wake disruption; neurotransmitter imbalance; sensory overload; prolonged cognitive decline	A2 systemic inflammation aligns with B2 global dysregulation; A3 organ support aligns with B3 stabilization scaffolding; A4 immune reset aligns with B4 reintegration	mismatch if B2 has multiple competing mechanisms; measurement noise in B higher	78	Both show a tipping phase where multi-stream signals diverge. Stabilization depends on restoring coherent coupling rather than fixing one number.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-004	P-04	bone fracture repair	rehabilitation after major depression episode	phase1 hematoma; phase2 inflammation; phase3 callus formation; phase4 remodeling	phase1 collapse; phase2 acute symptom peak; phase3 function scaffolding; phase4 identity and habit remodeling	nonunion; malunion; chronic pain	relapse; anhedonia persistence; functional collapse; social withdrawal	A1 hematoma aligns with B1 collapse as forced reset; A3 callus aligns with B3 scaffolding as temporary structure; A4 remodeling aligns with B4 long remodeling	mismatch if B relapse loops occur without clear structural injury analogue	74	Both require temporary scaffolds that later get remodeled. Failure appears as stalled consolidation or unstable remodeling.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-005	P-05	asthma exacerbation control	panic attack cycle stabilization	phase1 trigger exposure; phase2 bronchospasm cascade; phase3 rescue intervention; phase4 airway recovery	phase1 trigger cue; phase2 arousal cascade; phase3 grounding intervention; phase4 nervous system recovery	status asthmaticus; steroid overuse; rebound inflammation	fear of fear loop; avoidance reinforcement; sensitization	A2 bronchospasm cascade aligns with B2 arousal cascade; A3 rescue aligns with B3 grounding; A4 recovery aligns with B4 settling	mismatch if B triggers are internal and self-generated while A often external	80	Both are fast positive-feedback loops with a rescue window. The invariant is interrupting amplification early and preventing sensitization.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-006	P-06	gut microbiome recovery after antibiotics	sleep cycle restoration after burnout	phase1 disruption; phase2 instability; phase3 recolonization; phase4 stabilization	phase1 disruption; phase2 dysregulation; phase3 re-entrainment; phase4 stabilization	dysbiosis persistence; opportunist overgrowth; inflammation	insomnia persistence; hypervigilance; circadian drift	A3 recolonization aligns with B3 re-entrainment as rebuilding a stable attractor; A4 stabilization aligns with B4 stabilization	mismatch if B has intentional control loops and A has ecological constraints	72	Both recover by re-establishing a stable ecosystem rhythm. Failure is drift into a maladaptive attractor.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-007	P-07	chemotherapy marrow suppression and recovery	post-viral fatigue recovery pattern	phase1 insult; phase2 nadir; phase3 rebound; phase4 stabilization	phase1 insult; phase2 crash; phase3 rebound; phase4 stabilization	infection risk; delayed recovery; relapse	post-exertional malaise; oscillation; prolonged dysregulation	A2 nadir aligns with B2 crash; A3 rebound aligns with B3 rebound; A4 stabilization aligns with B4 stabilization	mismatch if B has unclear biomarkers for phase boundary detection	70	Both show predictable phase order and a vulnerability window around the nadir. The invariant is pacing and support through rebound without overshoot.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-008	P-08	chronic pain central sensitization	chronic anxiety sensitization loop	phase1 injury; phase2 nociceptive amplification; phase3 central sensitization; phase4 chronic maintenance	phase1 stressor; phase2 arousal amplification; phase3 threat sensitization; phase4 chronic maintenance	allodynia; pain spread; opioid dependence	hypervigilance; avoidance; reassurance seeking reinforcement	A3 central sensitization aligns with B3 threat sensitization; both maintain through prediction error biasing toward threat/pain	mismatch if A has peripheral drivers that persist while B often has none	84	Both convert transient signals into persistent prediction loops. The invariant is learning-based amplification and maintenance.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-009	P-09	immune tolerance induction in allergy	exposure therapy in phobia	phase1 sensitization; phase2 exposure dosing; phase3 tolerance building; phase4 maintenance	phase1 sensitization; phase2 graded exposure; phase3 extinction learning; phase4 maintenance	anaphylaxis risk; rebound sensitivity	dropout; context specificity; return of fear	A2 graded dosing aligns with B2 graded exposure; A3 tolerance aligns with B3 extinction learning; A4 maintenance aligns with B4 maintenance	mismatch if immune tolerance can be durable while fear extinction is context-bound	76	Both aim to recalibrate a reactive system through graded exposure. Failure modes track as overshoot risk and relapse risk.	Under 260 words.	has phase maps+alignment+mismatch+score
ISAM-010	P-10	stroke rehab motor relearning	language reacquisition after aphasia	phase1 acute injury; phase2 early rehab; phase3 neuroplastic relearning; phase4 consolidation	phase1 acute injury; phase2 early speech therapy; phase3 relearning; phase4 consolidation	learned nonuse; spasticity; plateau misread	learned nonuse; compensatory shortcuts; plateau misread	A3 relearning aligns with B3 relearning; plateau meaning is shared: either consolidation or stalled adaptation	mismatch if language has higher social constraint and feedback than motor tasks	79	Both are plasticity-driven relearning systems. The invariant is interpreting plateaus correctly and preventing maladaptive compensation.	Under 260 words.	has phase maps+alignment+mismatch+score