Datasets:
ClarusC64
/
endpoint-framework-transition-integrity-v0.1

Dataset card Data Studio Files
xet
Community
1
sample_id
string
source_framework
string
target_framework
string
concept
string
source_definition
string
target_definition
string
claim
string
option_a
string
option_b
string
task
string
correct_option
string
required_note
string
required_keywords
string
axis
string
difficulty
int64
CEFT-0001
Protocol
Publication
Primary endpoint
PFS per RECIST 1.1
OS at 12 months
Report OS as primary efficacy
Invalid correspondence, endpoint changed
Valid correspondence, same efficacy goal
Judge correspondence and write note
A
State PFS vs OS shift and flag endpoint substitution
PFS|OS|endpoint shift|protocol|publication
endpoint_identity
3
CEFT-0002
Protocol
Publication
Primary endpoint
Time to progression
PFS
Treat as same endpoint
Partial correspondence, definitions differ
Valid correspondence, equivalent metrics
Judge correspondence and write note
A
State TTP vs PFS difference and define event rules
TTP|PFS|event rule|difference|define
endpoint_definition
2
CEFT-0003
Protocol
SAP
Primary endpoint
ORR confirmed
ORR unconfirmed
Assume confirmation unchanged
Invalid correspondence, responder rule changed
Valid correspondence, same ORR
Judge correspondence and write note
A
State confirmed vs unconfirmed ORR and flag drift
confirmed|unconfirmed|ORR|responder|drift
responder_rule
2
CEFT-0004
SAP
Publication
Primary endpoint
PFS from randomization
PFS from first dose
Treat as same time origin
Partial correspondence, time origin differs
Valid correspondence, PFS label matches
Judge correspondence and write note
A
State randomization vs first dose and specify time zero
randomization|first dose|time zero|PFS|specify
time_origin
2
CEFT-0005
Protocol
Publication
Secondary endpoint
QoL mean change
QoL responder rate
Report as same patient benefit
Invalid correspondence, scale changed
Partial correspondence, map with transform
Judge correspondence and write note
A
State mean change vs responder rate and flag scale shift
mean change|responder rate|QoL|scale|shift
endpoint_scale
3
CEFT-0006
Protocol
Publication
Composite endpoint
MACE includes hospitalization
MACE excludes hospitalization
Treat composite as unchanged
Invalid correspondence, component removed
Partial correspondence, restate components
Judge correspondence and write note
A
State hospitalization component change and flag drift
MACE|hospitalization|component|change|drift
composite_components
3
CEFT-0007
Protocol
SAP
Endpoint hierarchy
Primary OS, secondary PFS
Co-primary OS and PFS
Assume hierarchy unchanged
Invalid correspondence, hierarchy altered
Valid correspondence, justified change
Judge correspondence and write note
A
State hierarchy change and require justification
primary|secondary|co-primary|hierarchy|justify
endpoint_hierarchy
3
CEFT-0008
Protocol
Publication
Endpoint window
12-month OS
24-month OS
Pool survival outcomes
Partial correspondence, window differs
Valid correspondence, same endpoint
Judge correspondence and write note
A
State 12 vs 24 month window and flag mismatch
12 month|24 month|window|OS|mismatch
window_definition
2
CEFT-0009
Protocol
Publication
Exploratory endpoint
Biomarker response exploratory
Biomarker response efficacy claim
Treat exploratory as confirmatory
Invalid correspondence, role escalation
Valid correspondence, exploratory retained
Judge correspondence and write note
A
State exploratory to efficacy shift and flag escalation
exploratory|efficacy|biomarker|escalation|drift
endpoint_role
3
CEFT-0010
Protocol
Publication
Non-inferiority margin
NI margin HR 1.25
NI margin HR 1.10
Report same NI conclusion
Invalid correspondence, margin changed
Partial correspondence, restate margin
Judge correspondence and write note
A
State margin change and flag decision shift
NI margin|1.25|1.10|decision|shift
decision_threshold
3