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metadata
tags:
  - biology
  - genomics
  - bulk-rna-seq
task_categories:
  - text-classification
license: cc-by-4.0

Virtual Cell — Distilled Bulk Encoder Example Dataset

A minimal sample dataset for verifying the data format and running quick end-to-end checks with ConvergeBio/virtual-cell-distil-bulk.

This dataset is not intended for training or evaluation. It contains a small number of samples and is not representative of a real distribution. Metrics produced from this dataset should not be interpreted.

Dataset contents

Derived from a public sepsis bulk RNA-seq study (GSE185263). Preprocessed into the model's input format as a minimal working example.

Split Samples Class distribution
train 88 53 sepsis / 35 healthy
validation 22 13 sepsis / 9 healthy

Labels: 0 = healthy, 1 = sepsis.

Loading

from datasets import load_dataset

ds = load_dataset("ConvergeBio/virtual-cell-distil-bulk-example")
train_ds = ds["train"]
val_ds   = ds["validation"]

Schema

Column Shape Type Description
bulk_expression [18301] float32 Log-normalised bulk gene expression, aligned to gene_names.txt
labels scalar int Class index (0 = healthy, 1 = sepsis)
disease_state scalar str Original label string
sample_id scalar str GEO sample accession ID

Citation

If you use this dataset, please cite the original study:

@article{baghela2022sepsis,
  author  = {Baghela, A. and others},
  title   = {Predicting sepsis severity at first clinical presentation: The role of endotypes and mechanistic signatures},
  journal = {EBioMedicine},
  year    = {2022},
  volume  = {75},
  pages   = {103776},
  doi     = {10.1016/j.ebiom.2021.103776},
  note    = {GEO accession: GSE185263},
}

If you use the Virtual Cell distilled bulk encoder, please also cite:

@article{convergecell2026,
  author = {ConvergeBio},
  title  = {ConvergeCELL: An end-to-end platform from patient transcriptomics to therapeutic hypotheses},
  year   = {2026},
  note   = {Preprint available on bioRxiv},
}

License

CC BY 4.0