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Several studies have found no increase in the overall frequency of birth defects in association with the use of spermicides, but the possibility of an increase in specific defects remains. We evaluated this possibility in a large case-control study. Infants with certain malformations (265 with Down's syndrome, 396 with... |
The authors examined the relations among children's effortful control, school relationships, classroom participation, and academic competence with a sample of 7- to 12-year-old children (N = 264). Parents and children reported on children's effortful control, and teachers and children reported on children's school rela... |
This article argues that the online environment is optimal for teaching prospective instructors how to develop and implement online courses. To support this claim, the author draws on hypertext theories to define the online course archive as a constructive hypertext and to describe the work the course archive is able t... |
Bundle pricing is commonly adopted by service firms managing multiple congestion-prone service facilities. Under bundle pricing, the firm charges a single price for all the services as a whole, and customers either purchase the bundle or do not purchase at all. This scheme is in contrast to a la carte pricing, under wh... |
Using blue Micro‐LED back light and red‐green quantum dot (QD) color converter (QDCC) is a full color display technology with great potential to achieve high resolution, color purity and luminous efficiency. In this work, we try a new method of ligands exchange, using 3‐Mercaptopropionic acid (MPA) ligands with two fun... |
Delayed rehabilitation in postmeniscectomy patients may be due to a slowly resolving axonal compression syndrome secondary to the use of the pneumatic tourniquet. Twenty-five patients who underwent meniscectomy were examined to determine whether the pneumatic tourniquet used during the procedure caused a neurological d... |
Summary form only given. In this demo we present a wearable device that enables to simultaneously collect information about the position of contacts and the magnitude and direction of contact forces applied by a hand to a grasped object. Such a device consists of a thimble that can be easily positioned on both human an... |
Household and cleaning products often contain both allergens and irritants. The aim of this double‐blinded, randomized, paired study was to determine whether patch testing with an allergen (hydroxycitronellal) combined with an irritant [sodium lauryl sulfate (SLS)] cause a stronger patch test elicitation reaction than ... |
The paper reports the results of a study carried out to evaluate the use of three 1‐alkyl‐3‐methylimidazolium‐based ionic liquids as non‐covalent coating agents for bare fused‐silica capillaries and additives of the electrolyte solutions (BGE) for CE of basic proteins in the co‐EOF separation mode. The three ionic liqu... |
The Italian Acute Stroke Study is a prospective, multicenter, randomized, clinical trial to evaluate hemodilution in acute stroke. Thirty—one centers will recruit 1,200 patients with a recent (< 12 hours) hemispheric acute stroke. Randomization is performed centrally, and patients are stratified by center and severity ... |
A total of 300 strains of Staphylococci isolated from various pathological sites of infection from different hospitals; these specimens derived from cases ofhuman infections were tested for staphylocoagulase activity. |
Test systems employing normal citrated rabbit plasma and the same substrate supplemented with inhibitors of thrombin and proteolytic enzymes (but notinfluencing the staphylocoagulase activity) were used for testing suspensions of bacteria and cell-free culture supernatants. A total of 200 strains clotted normal rabbit ... |
Background/Aims: Although several guidelines propose two or three measurements of home blood pressure (HBP) on each occasion, the actual status of multiple measurements is not clear in the practical management of hypertension. We surveyed the details regarding two measurements of HBP in patients with chronic kidney dis... |
This study aimed to understand coaches’ approaches to including children with disabilities in a community-based Australian rules football program for children. Football coaches for the program, called Auskick, completed an online survey providing qualitative and quantitative information about their experiences of inclu... |
of special education appeals hearings in Massachusetts. Due Process in Special Education details, in a highly readable fashion, what parents and school personnel can expect when they go to a hearing. Personal accounts and anecdotes of parents, educators, and hearing officers are liberally interspersed throughout, thus ... |
Coauthors Shih-Ming Li Chang and Lynn E. Frederiksen seek to undo Western assumptions about Chinese dance by describing it as contemporary rather than traditional— rooted in socio-historical phenomena rather than in purely aesthetic considerations— transnational rather than narrowly national, and creatively generated r... |
A novel ant colony optimization (ACO)-based multiuser detector (MUD) is designed for the synchronous multifunctional antenna array (MFAA)-assisted multicarrier direct-sequence code-division multiple-access (MC DS-CDMA) uplink, which supports both receiver diversity and receiver beamforming. The ACO-based MUD aims to ac... |
ABSTRACT Issues stemming from differences and similarities in cultural identities affect residents and workforces in care homes in Scotland, as they do across the United Kingdom. Theoretical guidance and policy drivers emphasise the importance of considering cultural diversity when planning or enacting person-centred c... |
Volume 2, Issue 4 July – August 2013 Page 16 Abstract: Knowledge Society, the warehouse of knowledge has its origin in knowledge management, comprising of knowledge acquisition, knowledge sharing, knowledge distribution, knowledge transfer, etc. Learning sciences being the sources of knowledge management, the automated... |
Forty-eight subjects read eight scenarios in which a decision was made between alternatives varying in arbitrariness. Nonarbitrary solutions were perceived as most deserving of support and unwarrantedly arbitrary solutions were judged least deserving. Warrantedly arbitrary solutions were rated between these two. Subjec... |
The diverse microbes that produce natural products represent an important source of novel therapeutics, drug leads, and scientific tools. However, the vast majority have not been grown in axenic culture and are members of complex communities. While meta-'omic methods such as metagenomics, -transcriptomics, and -proteom... |
Abstract Background: The α/β values for prostate cancer (PCa) are usually assumed to be low (1.0–1.8 Gy). This study estimated the α/β values of PCa from phase III randomized trials of conventional (CRT) versus hypofractionated (HRT) external beam radiotherapy (RT), reported as isoeffective in terms of their 5-year bio... |
This paper presents the neutronic design of an innovative fuel design proposed to be used in a Boiling Water Reactor (BWR). The study was carried out assuming different infinite lattice configurations calculated with HELIOS. The idea behind the lattice design is to use as much as possible the thorium conversion capabil... |
Abstract In this paper, the conversion of VO2(B) nanobelts under the hydrothermal condition in the absence/presence of dopant was studied. The synthetic conditions, such as the reaction temperature, reaction time, quantity of the dopants and kinds of dopants, were briefly discussed to prepare VO2(A) and W doped VO2(M) ... |
Computation offloading is a promising technique to help improve the performance as well as reduce the battery consumption of a smartphone app (short for application) by executing some parts of the app on a remote server. However, to make a favorable offloading decision, one has to consider lots of factors including the... |
We collected soil‐hydraulic property data from the literature for wildfire‐affected soils, ash, and unburned soils. These data were used to calculate metrics and timescales of hydrologic response related to infiltration and surface runoff generation. Sorptivity (S) and wetting front potential (Ψf) were significantly di... |
Background and Hypothesis: Thoracic aortic aneurysm (TAA) is characterized by progressive enlargement of the aorta and predisposes to life-threatening aortic dissection. Even among patients with monogenic causes of TAA, variable expressivity and incomplete penetrance hinders clinical decisions. Recent studies identify ... |
Experimental Design or Project Methods: We cultured SMCs directly from aortic tissues acquired at the time of aortic replacement surgery or heart transplantation. Mitochondria were labeled in live and fixed SMCs using the MitoTracker dye. We knocked down expression of COQ8B in SMCs using siRNA (siCOQ8B). The effects of... |
Results: Mitochondria in aortic SMCs showed a predominantly perinuclear distribution along with the appearance of a network of thin, filamentous extensions outward from the nucleus. Compared with siNeg controls, siCOQ8B decreased COQ8B RNA levels by approximately 90% on average across 5 knockdown experiments (80 to 95%... |
Conclusion and Potential Impact: Decreased expression of COQ8B via siRNA knockdown alters the expression of genes important for SMC homeostasis, causing the SMC to be more susceptible to oxidative stress and inducing apoptosis. Future studies will further explore the role of COQ8B on SMC contractility, matrix productio... |
In this work, we focus on quantifying speaker identity information encoded in the head gestures of speakers, while they narrate a story. We hypothesize that the head gestures over a long duration have speaker-specific patterns. To establish this, we consider a classification problem to identify speakers from head gestu... |
Novel Cu/nanoclay composites with antibacterial activity were synthesised by molten salt ion exchange method at two temperatures and at different times. The produced composites were characterised using X-ray diffraction (XRD), diffuse reflectance spectroscopy (DRS), X-ray fluorescence (XRF) and scanning electron micros... |
A steady increase in life expectancy has resulted in an equivalent increase in elderly patients who are more susceptible to diseases than young patients. In a recent study, we found that in both in vitro and in vivo models of ischemia/reperfusion (I/R), a loss of ATG4B is causatively associated with the increased sensi... |
Sialic acids are a subset of nine-carbon alpha-keto aldonic acids involved in various biological functions. Sialic acid on the sperm surface is closely related to sperm maturation and capacitation and sperm-egg recognition, which makes sperm negatively charged to avoid accumulation and covers some antigenic determinant... |
BACKGROUND |
Despite optimal treatment, myocardial infarction (MI) remains a major cause of death worldwide. Stem cell transplantation, as a promising therapy hoping to improve myocardial function and generate new myocardium, has been intensely studied for treating MI. |
OBJECTIVE |
To summarize the recent advance of stem cell transplantation for treating MI in clinical trials and preclinical studies. |
RESULTS |
Several types of adult stem cells have been applied to clinical trials and exerted beneficial effects against MI. The therapeutic effects of these stem cells are varied, modest and mostly depend on paracrine function. Embryonic stem cells and induced pluripotent stem cells, as well as their derivative cells, bring a ne... |
CONCLUSION |
Stem cell transplantation for treating MI in clinical trials has achieved modest therapeutic effect. The hurdles limiting the stem cell function define the direction of further research.Effect of Hypercarbia and Isoflurane on Brain Cell Death and Neurocognitive Dysfunction in 7-day-old Rats |
Background:Millions of neonates undergo anesthesia each year. Certain anesthetic agents cause brain cell death and long-term neurocognitive dysfunction in postnatal day (P)7 rats. Despite its intuitive appeal, a causal link between cell death and neurocognitive decline after anesthesia has not been established. If one ... |
The present invention belongs to the field of metal material, particularly to a low-temperature sintered directly hexagonal ferrite materials. Characterized in that a Bi O as the material for one component 32, to Bi 3 + substituted hexagonal ferrite is Ba 2 + , while an equivalent amount of divalent metal Me 2 + substi... |
This article is based on a case study of the management of curriculum change in primary schools. This was done by analyzing the management of curriculum change brought about by the introduction the History curriculum for the Year Four Primary Schools Standard-Based Curriculum. This instrumental case study employed a de... |
Many optimisation-based intrusion detection algorithms have been developed and are widely used for intrusion identification. This condition is attributed to the increasing number of audit data features and the decreasing performance of human-based smart intrusion detection systems regarding classification accuracy, fal... |
Recombinant calprotectin, consisting of 2 individual peptide chains also called migration inhibitory factor-related protein (MRP)-8 and MRP14, was tested for antimicrobial activity in a Candida albicans growth inhibition assay. Both chains contain HEXXH zinc-binding sites and might be expected to manifest zinc-reversib... |
Aim: We report patient safety and intraocular pressure (IOP) control after placement of a glaucoma drainage device (GDD) in eyes with a history of treated malignant uveal melanoma. Methods: A retrospective review of the records of patients with uveal melanoma was performed. Outcomes were local tumor recurrence, rate of... |
ESI-MS/MS investigation of the mono- and bis(guanylhydrazone) derivatives 1-5 based on adamantane and pentacycloundecane (PCU) skeleton was described. Elimination of neutral guanidine is the most abundant reaction channel in the case of 2,4-adamantyl and PCU derivatives 4 and 5, while the elimination of CH2N2 fragment ... |
Since the publication of Anna Coreth's fundamental work in 1959 the pietas austriaca has established its status as a key word for studying Habsburg politics and culture in early modern ages1. Its most effective topic was the encounter of Rudolf I with a priest carrying a viaticum. It formed the Habsburg mythos as the p... |
Matrix-assisted laser desorption ionization–time-of-flight mass spectrometry (MALDI-TOFMS) shows an excellent performance as a tool for microbial identification, which can analyze the strains not only for identification purposes, but also potentially for genetic typing. We present the typing results (compared with mult... |
BACKGROUND |
Obstructive sleep apnea (OSA) is associated with prothrombotic effects that could lead to venous thromboembolic disease. We performed a prospective cross-sectional study to determine the prevalence of snoring and risk of OSA in patients with acute pulmonary embolism (PE). |
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