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CONCLUSIONS |
We found that antigen-presenting cells have the capacity to stimulate specific T cells after the internalization and processing of Actinobacillus ghosts, as demonstrated by a strong specific T-cell response generated against the ghost antigens.Uptake of HIV and latex particles by fresh and cultured dendritic cells and ... |
Blood dendritic cells (DC) efficiently carry HIV‐1 and transmit infection to CD4+ T cells in the absence of productive infection of the APC. Fluorescent latex beads were used to define the endocytic pathways that may contribute to this non‐infectious pathway of virus carriage. Beads between 14 nm and 2300 nm in diamete... |
Globalization leads to the introduction of invasive species that are often accompanied by associated microorganisms, and this can lead to homogenization of both introduced hosts and microbes with the native biota. One such example is the invasive Eurasian woodwasp Sirex noctilio, which inoculates pines with an obligate... |
Centrosome amplification and chromosome abnormality are frequently identified in neoplasia and tumorigenesis. However, the mechanisms underlying these defects remain unclear. We here identify that MCT-1 is a centrosomal oncoprotein involved in mitosis. Knockdown of MCT-1 protein results in intercellular bridging, chrom... |
This paper proposes an evaluation of the performance of 5G communication between a user equipment (UE), which can be a car, and a 5G base station (gNB), under the influence of different numbers of UEs connected to that base station. There are two approaches to this communication evaluation: i) simulated mode, using Sim... |
CONTEXT |
Limited screening suggests that three germline mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene are not involved in sporadic pituitary tumorigenesis. Multiple novel mutations of this gene have since been identified in familial isolated pituitary adenoma cohorts. |
OBJECTIVE |
The objective of the study was to undertake full AIP coding sequence screening to assess for the presence of germline and somatic mutations in European Union subjects with sporadic pituitary tumors. |
DESIGN |
The study design was the analysis of DNA from peripheral blood lymphocytes and analysis of exons 1-6 and paraexonic intron sequences of AIP. Multiplex ligation-dependent probe amplification was used to screen separate sporadic pituitary tumor tissue samples for discrete and extensive deletions or mutations of the AIP g... |
SETTING |
The study was conducted in university tertiary referral Clinical Genetics, Molecular Biology, and Endocrinology Departments. |
RESULTS |
In 107 patients [prolactinomas (n =49), nonfunctioning tumors (n = 29), somatotropinomas (n = 26), ACTH-secreting tumors (n = 2), TSH-secreting tumors (n = 1)], no germline mutations of AIP were demonstrated. Among a group of 41 tumor samples from other subjects, a novel AIP mutation (R22X) was found in one sample in w... |
CONCLUSIONS |
AIP mutations do not appear to play a prominent role in sporadic pituitary tumorigenesis in this population of European subjects.BET on Independence |
Abstract We study the problem of nonparametric dependence detection. Many existing methods may suffer severe power loss due to nonuniform consistency, which we illustrate with a paradox. To avoid such power loss, we approach the nonparametric test of independence through the new framework of binary expansion statistics... |
The influence of pre-bond surface preparation on performance of adhesively-bonded composites subjected to impact was investigated in this study. Impact test was carried out on adhesively bonded graphite/epoxy composite specimens at different low impact energies ranging from 5 to 20 J using the drop-weight impact test. ... |
The phenotypes and receptors of the intraepithelial lymphocytes which are a major component of the mucosal immune system are of considerable interest. Intraepithelial lymphocytes, especially those of the intestines, are well documented. The nasal intraepithelial lymphocytes probably play a key role in the immune defens... |
Dead cells accumulating in the tissues may contribute to chronic inflammation. We examined the cause of impaired apoptotic cell clearance in human and murine lupus. Dead cells accumulated in bone marrow from lupus patients but not from nonautoimmune patients undergoing myeloablation, where they were efficiently removed... |
Abstract This article focuses on promoting cultural diversity among first year university students from different backgrounds, using an indigenous game called upuca. Learning Outcome 3 of Life Orientation was used as a vehicle to promote cultural diversity. The aim of this study was to describe and promote cultural div... |
174 Turanoğlu et al., Cough and Cold Medicines in Children / doi: 10.14744/hnhj.2018.48343 Materials and Methods This study was carried out between July 1, 2017, and October 30, 2017, and it included 220 physicians (pediatricians, general practitioners, and family medicine specialists), who actively provided services f... |
Opiate dependence is a significant public health concern linked to poor quality of life, comorbid psychiatric disorders, and high costs to society. Current opiate agonist treatments are an effective but limited intervention. Adjunctive interventions could improve and augment opiate agonist treatment outcomes, including... |
We build dynamic term structure models using a generalized structure of observable, forward-looking factors, where the dynamics of multi-horizon survey forecasts of inflation, output growth and monetary policy are modelled jointly with the physical process driving their realisations. When multiple-horizon forecasts dri... |
Given an integer g ≥ 2 and a class of finite groups let N(g, ) denote the order of the largest group in that a compact Riemann surface of genus g admits as a group of automorphisms. For the classes of all finite groups, cyclic groups, abelian groups, nilpotent groups, p-groups (given p), soluble groups and finally for ... |
The Duke and Mallette text covers a variety of research methodologies used in literacy. The editors asked recognized researchers in the particular methodologies covered to write the chapters and include exemplary studies illustrating the particular type of research. The impetus behind the text came from Duke and Mallet... |
A survey was conducted from 1993 through 1995 to monitor organochlorine pesticides and their metabolite residues in milk available in local Hong Kong markets. Of 252 samples analyzed, including pasteurized milk, fresh milk, and raw milk, 42 contained organochloride pesticide residues at levels exceeding the Extraneous ... |
Web 2.0 tools and environments have made tagging, the act of assigning keywords to on-line objects, a popular way to annotate shared resources. The success of now-prominent tagging systems makes tagging "the natural way for people to classify objects as well as an attractive way to discover new material". One of the mo... |
Careful choice of the animal model is essential, if research is to be conducted efficiently, by using the minimum number of animals in order to provide the maximum amount of information. Inbred strains of rodents provide an excellent way of controlling and investigating genetic variation in characters of interest and i... |
This study categorizes older adults living in rural areas by denture status, assesses the frequency of wearing dentures during meals, and determines whether denture status or use is associated with dietary quality or the number of foods avoided. A multi-ethnic population-based sample of adults ≥60 years (N = 635) in th... |
Plants have evolved a plethora of mechanisms to circumvent the potential damaging effects of living under low phosphorus availability in the soil. These mechanisms include different levels of organization, from root-shoot signalling at the whole-plant level to specific biochemical responses at the subcellular level, su... |
Cyberspace is reshaping the way businesses manage their sales and marketing assets. Unlike traditional media, such as TV, radio or newspapers, social media is characterized by freely available user-generated content. In addition to gaining phenomenal popularity as the web becomes accessible via all sorts of devices, th... |
This article presents the development, contributions, and future directions of the American Psychological Association, Division 17, Section for the Advancement of Women (SAW). Beginning with the formation of the Division 17 Ad Hoc Committee on Women in 1970, formalized in 1982 as the Division 17 Committee on Women, the... |
An application of artificial neural networks for accuracy improving of the microwave FET transistor noise modeling is presented in this paper. The proposed model is based on a basic transistor noise wave model whose noise wave temperatures are assumed to be constant over the operating frequency range. An artificial neu... |
Room-temperature operation of a continuous-wave Tm:YAP laser is reported. A 3 W laser diode in an end-pumped geometry is used to generate 730 mW of thulium laser output, which represents a conversion efficiency of 42% in terms of absorbed pump power. The laser operates on a number of lines in the wavelength range 1.965... |
To the editor, |
The serrated pathway is an established sequence to colorectal cancer (CRC), but little is known about the exact malignant potential of serrated polyps (SPs). Therefore, we have read with great interest the article by Holme et al 1 who evaluated the long-term risk of CRC in individuals with large (≥10 mm) SPs as well as... |
ABSTRACT This study aimed to assess aflatoxin and fumonisin intake through corn tortilla consumption in Veracruz city. Between October 2013 and February 2015, a total of 120 corn tortilla samples (2 kg samples, 40 samples per year) were randomly collected. Aflatoxins and fumonisins were quantified by high performance l... |
ABSTRACT Objective: Asthma severity is defined as the intensity of treatment required to achieve good control of asthma symptoms. Studies have shown that work-related asthma (WRA) can be associated with poorer asthma control and more severe symptoms than non-WRA. Associations between asthma medications and WRA status w... |
The title of this collection and the “note” from Georg Lukács which begins it, suggest that Mészáros has put together a document posing important theoretical and practical questions in need of concrete elaboration and critical discussion. Lukács writes that “The question you raised, concerning the determination of clas... |
Abstract Since 1993, the number of assisted living facilities has increased by 49.4%, surpassing nursing home growth (22%) and inviting a vast array of products whose purpose is to foster homelike settings within long-term care facilities. For housing and design professionals, the choice in specifying products to creat... |
The mode decision in the intra prediction of a H.264/AVC encoder requires complicated computations, and spends much time to select the best mode that achieves the minimum rate-distortion (RD). The complicated computations for the mode decision cause the difficulty in real-time applications, especially for software base... |
It is essential that government promotes manufacturers to develop reverse logistics for society. In this paper, a principal-agent model including other observable variables is presented, to analyze how government makes the optimization contract. Comparing with the basic principal-agent model, the principal-agent model ... |
A detailed consideration of the accuracy requirement for the compensation for the inverse synthetic aperture radar is presented. A new scheme of the motion compensation is submitted, in which the overall target, not any particular target scatter, is tracked to do the motion compensation. Some experimental results are g... |
Purpose/Background |
There are a few studies investigating the reproducibility of the Upper Quarter Y Balance Test (YBT-UQ) in adults. However, no study has determined test-retest reliability and the minimal detectable change of the YBT-UQ in adolescents from different age cohorts. The aim of the present study was to establish test-retest ... |
Methods |
In a school setting, 111 students (59 female, 52 male) aged 12-17 years performed the YBT-UQ twice, separated by one week. Normalized maximal reach distances (% arm length) for all three directions (i.e., medial, inferolateral, superolateral) and the composite score were used as outcome measures. Intraclass correlation... |
Results |
Irrespective of age cohort, reach arm, and reach direction, the measure of relative reliability ranged from "moderate-to-good" to "excellent" ICC values and the proxy of absolute reliability was rather small (i.e., SEM ≤ 7.6%). The MDC95% needed to identify relevant effects in repeated measurements of the YBT-UQ perfor... |
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