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A rapid, simple assay for screening large numbers of Escherichia coli colonies for production of certain plasmid-mediated β-lactamases (including TEM-1, TEM-2, HMS-1, SHV-1, OXA-1, PSE-1, PSE-4, and CEP-2) is described. The technique, a modification of the method of Slack et al. for detection of β-lactamase in limited ... |
Abstract In 2015, a solely owned Australian international university library in Vietnam underwent major changes that included a new staff structure. At the beginning of the year, an Irish-Australian Senior Library Manager was newly appointed to manage a team of Vietnamese library staff. The library service was reviewed... |
Intraoperative tumour spillage can be concerning during cancer excisions, given it can lead to tumour‐cell re‐implantation and local recurrence. Examples include bladder tumour recurrences post‐transurethral resection, or peritoneal spillage during laparotomy/laparoscopy for bowel and ovarian cancers. One approach to r... |
The recent theoretical and technological advancement in computer graphics has brought not only exciting changes to the computing field but also new challenges to computer science educators. One of the challenges is effective teaching of computer graphics to computer science students. Several speakers at the SIGGRAPH "9... |
Human T-cell lymphotrophic virus type I (HTLV-I) seroprevalence was 20% among Hawaiian Japanese migrants (issei) and their offspring (nisei) from Okinawa compared to 35% in similarly aged men who were lifetime residents of Okinawa. A control group of migrants from a nonendemic area of Japan, Niigata, had low rates of H... |
Understanding the kinetics and underlying physicochemical forces of liquid-liquid phase separation (LLPS) is of paramount importance in cell biology, requiring reproducible methods for the analysis of often severely aggregation-prone proteins. Frequently applied approaches, such as dilution of the protein from an urea-... |
The previous two chapters argued that beliefs are pervasively outsourced to other people and to the environment, and that belief revision often occurs in response to changes in the cues that scaffold our beliefs. In light of these facts, we need to ensure the scaffolding of better beliefs. We need, that is, to manage t... |
The adherence of 51Cr-labeled platelets to the subendothelium of rabbit aortas was inhibited in vitro and in vivo by high concentrations of dipyridamole (100 microM in vitro, 2.5 or 12.5 mg/kg in vivo). Dipyridamole (100 microM) inhibited release of 14C-serotonin from platelets that adhered to the subendothelium or to ... |
This study examined the determinants of adoption of risk management strategies in electronic banking (digital finance) among agro entrepreneurs in Ughelli North local Government area of delta state, Nigeria. Data were collected with the aid of structured questionnaire, administered on 79 respondents using two-stage sam... |
A sol-gel method was used to synthesise Sm2Ti2O7 photocatalysts. It was found that crystalline formation of pyrochlore phase Sm2Ti2O7 is promoted by addition of the PEG4000 template. Reduced particles aggregation was observed in the porous Sm2Ti2O7. The addition of PEG4000 lead to a slight increase in bandgap energy of... |
The double-stranded RNA (dsRNA)-binding domain of the human p68 kinase has been localized to the N-terminal half of the enzyme by using progressive deletion analysis and in vitro binding assays. To further define the domains responsible for binding to dsRNA, we cloned the mouse dsRNA-activated p65 kinase and used seque... |
This paper describes the methodology used to design and evaluate the strength and reliability of the thermal interface between the chip and heat sink (coverplate) in a TBGA first level package. TBGA is a new technology that is part of the new generation of organic ball grid array chip carriers that are quickly gaining... |
We present an exhaustive analysis of the problem of computing the relative entropy of two probabilistic automata. We show that the problem of computing the relative entropy of unambiguous probabilistic automata can be formulated as a shortest-distance problem over an appropriate semiring, give efficient exact and appro... |
The electrical properties of cells have long been regarded as potential label-free biophysical markers in cell status evaluation. However, previous studies have focused on the electrical properties of cell populations. Single-cell analysis, which can provide unique insight into the heterogeneous behaviors of cells, is ... |
Abstract Griseofulvin is an antifungal antibiotic used to treat various pathogenic mycotic diseases. The voltammetric behavior of griseofulvin at a hanging mercury drop electrode in Britton‐Robinson buffers of pH 2–11.5 was studied and discussed. A fully validated sensitive square‐wave adsorptive cathodic stripping vol... |
The standard IEEE 1901 has recommended windowed orthogonal frequency division multiplexing (OFDM) and wavelet OFDM as multicarrier techniques for broadband communications over the power line network. The former is one of multicarrier modulations mostly used by different wired and wireless broadband communication standa... |
Abstract Timberfabric structures, developed at IBOIS, are a new family of timber constructions based on the logic and principles of man-made fabrics. Modular elements called “timberfabric modules” are generated by curving and connecting two thin wooden panels. This paper concerns the study of vaults obtained by assembl... |
Received October 26, 1995, from the Perinatology Research Facility, Department of Obstetrics and Gynecology (A.G., R.A.F., ].T., D.M.S.), <tnd Dep<~rtment of Pathology <J.A.W., H .J.M.), Georgetown University Medical Center, Washington, DC . Revised manuscript accepted for publication February 2, 1996. Address correspo... |
Transferability of the first-principle pseudopotentials is tested for a pseudoatom embedded in a jellium. The Hamann's pseudopotential (Phys. Rev. B 40 (1989) 2980) and its separable form are analyzed in this transferability test. Elements examined in this paper are classified into two; the first class is elements in w... |
Background: In the Western world, it is widely accepted as natural – and seen almost as a law of nature – that mankind is divided into two sexes or genders – males and females. In many cultures and societies, however, more than two sex and/or gender categories are recognized, which in some instances refer to the biolog... |
Regularization is an important method for solving a wide variety of inverse problems in image processing. In order to optimize the reconstructed image, it is important to choose the optimal regularization parameter. The unbiased predictive risk estimator (UPRE) has been shown to give a very good estimate of this parame... |
Background: |
It is estimated that the U.S. will spend $370 billion in 2019 on pharmaceuticals and by 2020 the cost of cancer care will be approximately 158 billion. Cost containment strategies for high cost drugs are needed. In 2019 global sales from subcutaneous (SubQ) bortezomib manufactured by Takeda® will exceed $1 billion. Th... |
Methods: |
Boston Medical Center Health System is a 500 plus bed integrated delivery network which not only functions as payer but also as a provider. A protocol was implemented to switch patients from SubQ to IV bortezomib. Patients had to complete 4 cycles of SubQ bortezomib and have either Grade 1 or no BIPN to qualify to swi... |
Results: |
Eleven patients have received at least 1 cycle of IV generic bortezomib for various indications from Nov 2018 to June 2019, with minimum of 2 doses and maximum of 16 doses. The diseases for which bortezomib was being used included multiple myeloma (n= 6) and AL amyloidosis (n= 2), renal transplant rejection and thromb... |
Conclusion: |
We describe a method to switch from subcutaneous bortezomib to generic IV bortezomib instituted at a large academic medical center as a cost containment strategy. This has resulted in no new cases of neuropathy in our growing data set. Global adoption of this protocol has the potential to substantially reduce drug cos... |
Sanchorawala: Celgene: Research Funding; Takeda: Research Funding; Proclara: Consultancy, Honoraria; Caelum: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees; Janssen: Research Funding; Prothena: Research Funding. Sloan:Merck: Other: endpoint review commitee; Abbvie: Other: E... |
A Novel Approach to Design a Scalable Air Quality Monitoring System |
The research presents a novel approach to carbon dioxide (CO2) emissions monitoring and access to local air quality data. The approach applies the advanced Internet of things technology to design a mobile telemetry system for CO2 data collection and processing in order to be presented as a value-added application to mo... |
The purpose of this research was to describe the overweight prevalence and factors potentially associated to it in adults residents in areas of social exclusion. The sample consisted of 3214 individuals, aged 20 to 69 years, in shanty town in Maceió-AL, northeast of Brazil. Body mass index (BMI) was used in the nutriti... |
Gewasbescherming jaargang 35, nummer 4, juli 2004 Pagina 221 [ W C S D A G 2 0 0 4 biocontrol are bacteria from the genus Pseudomonas. They can produce antibiotics and siderophores, weakening the pathogen in the soil. Root colonisation by selected strains result in induce systemic resistance (ISR) effective against a b... |
Self-assembled quantum dots are often modeled by continuum models seffective mass or k ·pd that assume the symmetry of the dot to be that of its overall geometric shape. Lens-shaped or conical dots are thus assumed to have continuous cylindrical symmetry C‘v, whereas pyramidal dots are assumed to have C4v symmetry. How... |
We have developed a method for morphological evaluation of retinal pigment epithelium (RPE) with minimal perturbation of RPE-Bruch's membrane-choriocapillaris complex (RBCC). To prepare RBCC, the anterior segments of the eye were removed. The remaining eye cup was radially cut into 4 to 6 pieces from periphery to the o... |
To evaluate the role of zinc in Escherichia coli alanyl-tRNA synthetase, hydrodynamic measurements and circular dichroism spectra were obtained for the zinc-depleted protein and compared with those of the native enzyme. At a protein concentration of 5 mg ml(-1), pH 7.5, the sedimentation coefficient (s(20,w)) was 6.3 S... |
It is possible to associate plane tessellations with certain digraphs over the set of vertices V = Z/nZ. This association enables a geometrical, and in general simpler, approach to their study. We use this relation for obtaining the maximum order, minimum diameter and minimum mean distance of a family of bipartite digr... |
ABSTRACT The claim that restorative justice emerged in response to the failings of the traditional criminal justice system is frequently made and rarely challenged in the restorative justice literature. It is stated unproblematically, as though it is an unassailable fact rather than a powerful truth claim, thereby posi... |
Due to their large yolk size, salmonid embryos take a longer time for epiboly movements and germ ring closure compared with most other teleost species. Here we analyzed the germ ring closure, tail bud formation and development of the notochord and somites in rainbow trout using live embryo imaging and in situ hybridiza... |
Objective: To determine the educational impact of placing partner violence resource information in a medical setting. Method: A cross-sectional study with a structured interview. Setting: Emergency department (ED) in an urban academic medical center. Participants: adult patients and visitors. Interventions: Educational... |
A neural network architecture was designed for locating word boundaries and identifying words from phoneme sequences. This architecture was tested in three sets of studies. First, a highly redundant corpus with a restricted vocabulary was generated and the network was trained with a limited number of phonemic variation... |
BACKGROUND |
Previous studies show that women working in prostitution do not use routine health services appropriately. Little is known about the nature and frequency of service contacts or barriers to access. This information is needed if use of current services by this group is to improve. |
AIM |
To identify barriers reducing access to health services by street prostitutes, and to identify current patterns of use. |
DESIGN OF STUDY |
Cross-sectional survey. |
SETTING |
Inner-city Bristol. |
METHOD |
Seventy-one female street-based prostitutes were interviewed about their experiences of health services. |
RESULTS |
The women had frequent contacts with healthcare providers. The general practitioner (GP) was the main source of all types of care. Although 83% (59/71) were registered with a GP, 62% (36/59) had not disclosed their work. Only 46% (33/71) had been screened for sexually transmitted infection in the previous year and 24% ... |
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