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The study aimed to estimate the technical efficiency and the factors affecting the inefficiency of wheat production farms. The Pareto curve was used to determine the importance of the problems facing farmers in the production process ‘the actual and potential production and the number of production losses in the study ... |
Data from experimental studies on the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on cartilage is reviewed. There is evidence from this data that some NSAIDs exert a harmful effect, but also that other NSAIDs do not influence cartilage metabolism or could even have a moderate beneficial effect. So far t... |
Abstract |
Biochar is a by-product obtained from biomass pyrolysis. Due to the potential role in improving soil fertility and remediation of contaminated soil, biochar has attracted increasing attention in recent years. Biochar can remediate organically contaminated soil via adsorption and biodegradation, during which organic co... |
Aphids are significant pests to many host plant species throughout the world. Aphids are on the other hand parasitized by a variety of parasitoid wasps which can potentially be used as biocontrol agents. The focus of the present study is on the pattern and distribution of the aphids and their parasitoids in the Kurdist... |
This paper proposes a framework to track faces in color video sequences. The Adaptive Support Vector Tracker (ASVT) combines face detection with target tracking through using an adaptive filter in unconstrained videos. The adjacent locations of the target point are predicted in a search window reducing the number of im... |
OBJECTIVES |
Implementing disaster exercises in different parts of the health system is one of the important steps in providing and developing disaster risk management plans. Considering the importance of promoting health system preparedness through exercise, the present study aimed to identify and explain necessary and original co... |
METHODS |
The study was a qualitative content analysis. Data were collected by purposeful sampling through in-depth and semi-structured individual interviews with 25 health professionals in disaster. Directed content analysis was used to analyze the data, which extracted the initial codes after performing the recorded interviews... |
RESULTS |
The data analysis resulted in the production of 100 initial codes, 14 subcategories, 6 main categories of "coordination and information management," "standards and indicators," "conduction and control of the process," "logistic management and supplies," "management of treatment operation," and "management of health ope... |
CONCLUSIONS |
The findings of this study can greatly increase the attention of senior managers to preparedness in all areas of the health system, especially managers of prehospitals and hospitals who are the forefront of the response to the disaster. The findings of this study can be considered as a guideline for the implementation ... |
Herpesvirus sylvilagus was propagated in juvenile cotton tail rabbit kidney cells and purified from the cytoplasmic fraction of the infected cells. The purification procedure included zonal centrifugation through a 5 to 30% dextran t-10 gradient, followed by equilibrium centrifugation in a 5 to 50% potassium tartrate g... |
We consider the evaluation of the Number of Degrees of Freedom (NDF) of the field radiated by square sources in the far zone. The analysis is performed by employing a Singular-Value Decomposition (SVD) of the radiation operator in the two-dimensional scalar case. To this end, we start the analysis from simple geometrie... |
A day-ahead microgrid energy management optimization scheduling scheme is proposed in this paper. The object is to optimize the output power of DERs (distributed energy resources, DERs). The objective function includes operating cost and maintaining cost of lithium battery and fuel cell, the interruptible compensation ... |
We present a case study of metabolism, life history and aging in the western terrestrial garter snake (Thamnophis elegans). Early research in the field supported the rate-of-living hypothesis as an explanation of aging, which was based on an apparent negative relationship between mass-specific metabolic rate and lifesp... |
The solar selective absorber layer is the key part in the heat energy collector. In this study, optical properties of SiO2/Ti/SiO2 multilayer films with the different thickness individually are studied to meet the better optical requirement of a solar selective absorber layer. The variation of the optical reflctance du... |
The fear of fuel depletion necessities the integration of energy saving methodologies for electric power generation. Diesel engines are common for back-up/standby electric power generation units. Being compression-ignition based, in contrary to gasoline engines, the enrichment of the air intake of diesel engines with H... |
Primary percutaneous transluminal coronary angioplasty (PTCA) with the insertion of a stent is a well-established procedure for management of coronary artery disease. Infected pseudoaneurysms following PTCA and stenting are very rare and have poor outcomes if not managed properly. We are presenting a case of a man aged... |
Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to the epidermal growth factor homology domain repeat A of the low-density lipoprotein receptor (LDLR) at the cell surface and disrupts recycling of the internalized LDLR. As a consequence, the LDLR is rerouted to the lysosomes for degradation. Although PCSK9 ... |
told in the cover blurb that "All of the translations are new with the exception of The Conflict of the Faculties. . . . " Because of how it brings together all the chief writings on religion from Kant's critical period in one volume, and in accurate translations, with the additional scholarly apparatus needed to make ... |
BACKGROUND |
In 2013, the French National Cancer Institute initiated the AcSé program to provide patients with secure access to targeted therapies outside of their marketed approvals. Efficacy and safety was then assessed using a two-stage Simon phase II trial design. When the study design was designed, crizotinib was approved only... |
PATIENTS AND METHODS |
Advanced NSCLC patients with c-MET ≥ 6 copies, c-MET-mutated, or ROS-1-translocated tumours were enrolled in one of the three cohorts. Patients were treated with crizotinib 250 mg twice daily. Efficacy was assessed using the objective response rate (ORR) after 2 cycles of crizotinib as primary outcome. Secondary outcom... |
RESULTS |
From August 2013 to March 2018, 5606 patients had their tumour tested for crizotinib targeted molecular alterations: 252 patients had c-MET ≥ 6 copies, 74 c-MET-mutation, and 78 ROS-1-translocated tumour. Finally, 25 patients in the c-MET ≥ 6 copies cohort, 28 in the c-MET-mutation cohort, and 37 in the ROS-1-transloca... |
CONCLUSIONS |
Crizotinib activity in patients with ROS1-translocated tumours was confirmed. In the c-MET-mutation and c-MET ≥ 6 copies cohorts, despite insufficient ORR after two cycles of crizotinib, there are signs of late response not sufficient to justify the development of crizotinib in this indication. The continued targeting ... |
CLINICAL TRIAL NUMBER |
NCT02034981.Three Early Russian Bibliographers |
This paper introduces three early Russian contributors to bibliography: N. I. Novikov, V. S. Sopikov, and V. G. Anastasevich, who worked at the end of the eighteenth and beginning of the nineteenth centuries. Their lives and main bibliographic works are viewed in the contexts of Russia in their time and of Western Euro... |
We present the superconformal gauge theory living on the world-volume of D3 branes probing the toric singularities with horizon the recently discovered Sasaki-Einstein manifolds L. Various checks of the identification are made by comparing the central charge and the R-charges of the chiral fields with the information t... |
Alternative splicing patterns are regulated by RNA binding proteins that assemble onto each pre-mRNA to form a complex RNP structure. The polypyrimidine tract binding protein, PTB, has served as an informative model for understanding how RNA binding proteins affect spliceosome assembly and how changes in the expression... |
This article serves as a primer to make the neuroimaging literature more accessible to the lay reader and to increase the evaluative capability of the educated consumer of cognitive neuroscience. This special issue gives gifted education practitioners and researchers a primary source view of current neuroscience releva... |
In this paper, we consider the problem of global output feedback stabilization for a class of nonlinear systems whose nonlinearities are assumed to be bounded by both low‐order and high‐order nonlinearities multiplied by a polynomial‐type output‐dependent growth rate. Instead of the previously proposed dual observer, b... |
Modular construction allows for a faster, safer, better controlled, and more productive construction process, yielding quality results with low risk and controlled costs. However, despite the potential advantages of this methodology, its adoption has remained slow due to the reasonably high degree of standardisation an... |
In this paper, an advanced High Voltage (HV) IGBT technology, which is focused on low loss and is the ultimate device concept for HV IGBT, is presented. CSTBTTM technology utilizing “ULSI technology” and “Light Punch-Through (LPT) II technology” (i.e. narrow Wide Cell Pitch LPT(II)-CSTBT(III)) for the first time demons... |
The virucidal spectrum of a high concentration alcohol mixture (80% ethanol and 5% isopropanol) was determined for a broad series of lipid-enveloped (LE) and non-lipid-enveloped (NLE) viruses covering all relevant blood-borne viruses. LE viruses were represented by human immunodeficiency virus (HIV), bovine viral diarr... |
Supplemental digital content is available in the text. Background Current doctoral degree options may not meet needs of nurses desiring educator roles in academic or health care settings. Purpose The purpose of the study was to assess preferences for existing terminal degree options for nurse educators and determine th... |
A Geographical Information System (GIS) based methodology has been used to construct the black carbon (BC) emission inventory for the Indian geographical region. The distribution of emissions from a broader level to a spatial resolution of 1° × 1° grid has been carried out by considering micro level details and activit... |
ABSTRACT Introduction: Surgically induced necrotizing scleritis (SINS) is a rare but serious disorder that can develop many years after strabismus surgery. It is generally treated with high-dose steroids or immunosuppression. Case report: We describe a patient with Varadi Papp syndrome and congenital fibrosis of the ex... |
Like all taxa, populations of aquatic insects may respond to climate change by evolving new physiologies or behaviors, shifting their ranges, exhibiting physiological and behavioral plasticity, or by going extinct. We evaluated the importance of plasticity by measuring changes in growth, survival, and respiratory pheno... |
Recent studies have shown that the course of lupus glomerulonephritis is usually one of inexorable progression to renal failure despite intensive treatment with glucosteroids. Seventeen patients were treated with low doses of prednisone (<20 mg/day) and azathioprine (2–3 mg/kg/day) for 6 to 36 months. Diagnosis of the ... |
Two experiments were conducted to determine whether the auditory and visual systems process simultaneously presented pairs of alphanumeric information differently. In Experiment 1, different groups of subjects were given extensive practice recalling pairs of superimposed visual or auditory digits in simultaneous order ... |
Informal caregivers of stroke survivors experience elevated chronic stress and are at risk of developing depressive symptoms. The cumulative effects of chronic stress can increase allostatic load and dysregulate biological processes, thus increasing risk of stress-related disease. Stress-induced alterations in the patt... |
We read with interest the study by Lubitz et al1 on stroke as the initial manifestation of atrial fibrillation (AF) in the Framingham Heart Study. Stroke occurred as the initial clinical expression of AF among 1.7% of patients on the same day, in 3.4% within 30 days before, in 3.7% within 90 days before, and among 4.8%... |
There are 2 possible ways of understanding these results. First, as acknowledged by the authors, stroke occurring at different time points within a year before AF detection could be regarded as the first clinically evident consequence of AF. In contrast, AF could be the consequence of the index stroke among some partic... |
Abstract Dual frame surveys, in which independent samples are selected from two frames to decrease survey costs or to improve coverage, can present challenges for regression estimation because of complex designs and unknown degree of overlap. In this research, we developed three nonparametric regression estimators in d... |
The high-pressure behavior of the direct and indirect band gaps in zinc-blende-structure SiC is examined with use of self-consistent {ital ab} {ital initio} pseudopotential calculations. The fundamental band gap from {Gamma}{sub 15}{sup {ital v}} to {ital X}{sub 1}{sup {ital c}} is found to decrease linearly with press... |
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