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Because of the inability of strength tests to accurately discriminate between low back pain patients and healthy subjects, a multifactorial evaluation of low back pain patients is warranted. It is postulated that measurements of endurance, kinematics, postural stability, and coordination, in addition to strength, are n...
Erythroplakia of the oral cavity is a specific disease entity which must be differentiated from other specific or nonspecific inflammatory oral lesions, although this can only be done in most cases by biopsy. A series of 58 cases of oral erythroplakia has been retrieved from 65,354 consecutively accessioned biopsy‐surg...
PURPOSE
To determine the prevalence of hepatitis C virus antibodies (anti-HCV) in patients with sickle cell disease.
PATIENTS AND METHODS
Between 1983 and 2001, 150 patients from the Howard University Hospital Center for Sickle Cell Disease were screened for HCV antibody (52% women, 48% men, mean age 34 years). Frozen serum samples from 56 adult sickle cell patients who had participated in previous surveys (1983-92) of HIV and HTLV-1 serology and who wer...
RESULTS
Antibodies to HCV were detected in 53 patients (35.3%). Of the 55 patients who had frozen serum samples tested in 1992, 32 (58%) were reactive for anti-HCV, while only 21 of the 95 patients (22%) tested after 1992 were positive for HCV antibodies (P<0.001). Thirty-nine of 77 patients (51%) who received more than 10 uni...
CONCLUSION
The prevalence of HCV antibody and iron overload is directly related to the number of blood transfusions in patients with sickle cell disease. The prevalence of HCV infection has decreased significantly, since blood donor screening for HCV became available. Chronic HCV infection and iron overload place sickle cell pati...
This paper tackles the tracking control of flexible hypersonic vehicle (FHV) with mismatched uncertainties by utilizing the adaptive nested terminal sliding mode control method. The controllers of velocity loop and altitude loop are designed separately based on the control-oriented model which is obtained by simplifica...
Copying and reprinting. Material in this book may be reproduced by any means for educational and scientific purposes without fee or permission with the exception of reproduction by services that collect fees for delivery of documents and provided that the customary acknowledgment of the source is given. This consent do...
Cancer cells exhibit increased use of nutrients, including glucose and glutamine, to support the bioenergetic and biosynthetic demands of proliferation. We tested the small-molecule inhibitor of glutaminase CB-839 in combination with erlotinib on epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer...
In this work, an improved wet bonding method was developed for strengthening of fiber-reinforced polymer. A self-made roughened carbon fiber–reinforced polymer sheet (hereinafter referred to as RFRP sheet) was externally attached to the surface layer of a nano-kaolin-modified concrete test piece to form an RFRP–concret...
SUMMARY: A systematic study of plasma lipids and lipoproteins was carried out in II cases of Friedreich's ataxia and 6 cases of familial spastic ataxia (Charlevoix-Saguenay disease) using II healthy normolipidemic volunteers of comparable age and sex as controls. No differences were noted in the fatty acid profile of t...
Efficient eye movement planning in both space and time is vital for visual perception. Previous studies showed that human eye movements were consistent with an optimal searcher during visual search; however, we found that such a model could not fully explain the spatial control of eye movements and it completely ignore...
This paper conducts a comprehensive study of the optimal exercise policy for an executive stock option and its implications for option cost, average life, and alternative valuation concepts. The paper is the first to provide analytical results for an executive with general concave utility. Wealthier or less risk-averse...
The notion of an L1–norm density estimator process indexed by a class of kernels is introduced. Then a functional central limit theorem and a Glivenko–Cantelli theorem are established for this process. While assembling the necessary machinery to prove these results, a body of Poissonization techniques and restricted ch...
OBJECTIVE
To examine family-based transmission of the number of 5' flanking arginine vasopressin V1a receptor (AVPR1A) microsatellites, which include [(GATA)(14)] and complex [(CT)(4)-TT-(CT)(8)-(GT)(24)] repeats, in probands with a prepubertal and early adolescent bipolar disorder phenotype (PEA-BP). Preferential transmission o...
METHODS
Probands were 83 participants in an ongoing controlled study of PEA-BP. The PEA-BP phenotype was defined by DSM-IV mania with at least one of the cardinal symptoms of mania (elation and/or grandiosity) to avoid diagnosing mania only by symptoms that overlapped with those for attention-deficit hyperactivity disorder (AD...
RESULTS
Preferential transmission of AVPR1A GATA or complex repeats was not significant for hypersexuality or uninhibited people-seeking, using the transmission disequilibrium test. Similarly, case-control analyses found no significant associations between hypersexuality or uninhibited people-seeking and the number of AVPR1A G...
CONCLUSION
Preferential transmission of AVPR1A to hypersexual or uninhibited people-seeking probands was not supported.Dispersive liquid-liquid microextraction with in situ derivatization coupled with gas chromatography and mass spectrometry for the determination of 4-methylimidazole in red ginseng products containing caramel col...
A rapid analytical method was developed for the determination of 4-methylimidazole from red ginseng products containing caramel colors by using dispersive liquid-liquid microextraction with in situ derivatization followed by gas chromatography with mass spectrometry. Chloroform and acetonitrile were selected as the ext...
This cross-sectional study was carried out in October, 2001, with the aim of measuring formaldehyde levels in 399 homes representative of those in the central districts of Ankara province. Measurements were carried out with a Formaldemeter 400 in the living rooms and kitchens of these homes. The average formaldehyde le...
In recent years the demand for cytogenetic analysis has been increasing dramatically. How ever, the basic steps in the process of specimen preparation and analysis are not amenable to large scale processing of samples. Elements of a semi automated system for the preparation and analysis of human chromosomes are describ...
During development, the heart growths through addition of progenitor cells to the poles of the primordial heart tube. In the zebrafish, wilms tumor 1 transcription factor a (wt1a) and b (wt1b) are expressed in the pericardium, at the venous pole of the heart. From this pericardial layer, the proepicardium emerges. Proe...
Breast tumors contain both transformed epithelial cells and non‐transformed stroma cells, and accumulating experimental evidence strongly suggests that this heterogeneous tumor microenvironment influences tumor growth and metastasis. Previously, we demonstrated that MAPK/ERK kinase kinase 1 (MEKK1) regulates gene expre...
Abstract Geographically structured genetic variants provide an effective means to assess sources of natural selection and mechanisms of adaptation to local environments. Correlated selection pressures along environmental gradients favor subdivision of genomes through chromosomal rearrangement. This study examines popul...
From the outset, lipids have been diffi cult to study, as exemplifi ed by J. L. W. Thudichum’s often cited naming of sphingosin[e] “in commemoration of the many enigmas which it presented to the inquirer” ( 1 ). Even today, when one can clone, express, and knock out (and in) genes for enzymes that metabolize, transport...
Purpose. Determining the levels of environmental pollution by electromagnetic sources and providing recommendations on how to prevent the impact of negative factors on human health. Design/methodology/approach. Particular attention is paid to the spread of electromagnetic fields within the urban system of Kremenchuk, n...
Increased levels of cognitive activity may improve general cognitive function in older adults and potentially increase cognitive reserve, protecting against the onset of dementia associated with syndromes like Alzheimer's disease. To test the efficacy of cognitive training administered online, 18 participants (11 cogni...
Unstable thermonuclear burning on the surface of accreting neutron stars is commonly observed as type I X-ray bursts. The flux released during some strong bursts can temporarily exceed the Eddington limit, driving the neutron star photosphere to such large radii that heavy-element ashes of nuclear burning are ejected i...
T average life expectancy of the U.S. population continues to increase and with it there is a corresponding increase in the incidence of disease directly correlated with increasing age, such as prostate cancer in males and breast cancer in females. Statistics reveal that by age 80 a woman has a 1 chance in 9 of develop...
Water oxidation is the key step in both natural and artificial photosynthesis to capture solar energy for fuel production. The design of highly efficient and stable molecular catalysts for water oxidation based on nonprecious metals is still a great challenge. In this article, the electrocatalytic oxidation of water by...
Phalan et al. contest our findings (De Oliveira Silva et al., 2016) (henceforth RdOS) on the relationship between livestock consumption and emissions. First, they doubt the likelihood of avoiding expansion of pastureland while increasing production and suggest that deforestation may still happen due to cropping area ex...
This article is protected by copyright. All rights reserved.COVID-19 vaccine trials: The potential for “hybrid” analyses
Background: Although several COVID-19 vaccines have been found to be effective in rigorous evaluation and have emerging availability in parts of the world, their supply will be inadequate to meet international needs for a considerable period of time. There also will be continued interest in vaccines that are more effec...
The ECG digital signal processing evolved in last decade and the need to store and transmit ECG signal data is continuously increasing. This paper involves analysis of an enhanced ECG compression and de-compression method. The method is evaluated on the basis of different compression and quality parameters like compres...
Dichotic stop-consonant-vowel identification was investigated in two experiments using two groups of learning-disabled children demonstrating clinical manifestations of auditory-processing disorders, and two groups of matched, control subjects. Two-item, forced-choice paradigms were used in both experiments. Overall (t...
The triple catastrophe that began in Japan on March 11, 2011 was unprecedented. In the wake of the devastating earthquake and tsunami, the Fukushima Daiichi nuclear power plant crisis deteriorated to a Level 7 nuclear accident, the most severe level reserved by the International Atomic Energy Association for accidents ...
Abstract The updated regulatory framework for demonstrating that future 8-hr ozone (O3) design values will be at or below the National Ambient Air Quality Standards (NAAQS) provides guidelines for the development of a State Implementation Plan (SIP) that includes methods based on photochemical modeling and analytical t...
ONE OF THE reasons science seems remote and mysterious to non-scientists, even as we are daily ever more surrounded with its products, is that its story is so rarely told in terms of human lives. Conventional scientific articles, for example, give us welldigested final results, but deliberately conceal the process and ...
This paper discusses a novel hybrid approach for text categorization that combines a machine learning algorithm, which provides a base model trained with a labeled corpus, with a rule-based expert system, which is used to improve the results provided by the previous classifier, by filtering false positives and dealing ...
Primary actinomycosis of breast is a rare disease with only a few cases reported in the literature. We present a case of a 25‐year‐old lactating woman with primary actinomycosis of breast which was diagnosed on cytology. The patient presented with lump in left breast with dull aching pain. Fine‐needle aspiration cytolo...
A distributed dynamic slot assignment scheme for multi-channel Time Division Multiplex Access (TDMA) based wireless Ad Hoc networks is presented in this paper.As exclusive control channels are introduced,hidden terminals are enable to receive packet whereas transmit packets are avoided. Similarly,exposed terminals are ...
Vendor-managed inventory (VMI) is a commonly used collaborative inventory management policy in which manufacturers/vendors manage the inventory of retailers and take responsibility for making decisions related to the timing and extent of inventory replenishment. Several prerequisites exist for successfully implementing...
The participation of business in partnership initiatives for sustainable development has intensified significantly since the Earth Summit in Rio de Janeiro in 1992. By 2014, there were about 1,000 voluntary commitments and multilateral partnerships in various fields of activity involving partners from the corporate sec...