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than the virtual address space. In earlier implemen-
tations of the SDM memory the addresses of all physical
locations had to be scanned to determine which locations
to activate. This is time-consuming, and massive parallel
hardware support is needed for other than small appli-
cations. This paper introduces a new mechanism for
finding the active locations. Using this access
mechanism, the access time may be speeded up several
orders of magnitude.Systolic 3 D first-pass myocardial perfusion MRI
Introduction: First-pass myocardial perfusion imaging (MPI) is now an established tool for the assessment of ischemic heart disease, and the most widely used protocols involve 2D multi-slice acquisition. Three-dimensional (3D) MPI is potentially advantageous due to its contiguous spatial coverage and high SNR [1], and ...
Three hundred and seventy-one children below 16 years, with newly diagnosed acute myeloid leukaemia, were included in six consecutive GATLA/GLATHEM protocols, from November 1967 to December 1987. The study was divided in three periods: 1967 to 1975, 1976 to 1982, and 1983 to 1987. Three induction schedules were used du...
Abstract Introduction While academics are frequently engaged in research activities and subsequent dissemination of results through publication, all too often they occur without health practitioner involvement. While there are contemporary expectations that health practitioners will be active contributors to their disc...
Apple replant disease (ARD) is a common disease in apple producing areas, and more and more evidence shows that soil-borne pathogens are the main factor. However, most of the drugs used to kill microorganisms are not friendly to the environment. Therefore, there is an urgent need to identify a method that can effective...
Reducing power consumption of computational systems in the use-phase has become a significant focus to decrease thermal impacts and overall energy consumption of computing systems while having battery life benefits for increasingly mobile computing products. It is also a major driver of the sustainability of these syst...
We show that simulations of magnetohydrodynamic turbulence in the multiphase interstellar medium yield an E/B ratio for polarized emission from Galactic dust in broad agreement with recent Planck measurements. In addition, the B-mode spectra display a scale dependence that is consistent with observations over the range...
MEMS (Micro Electro Mechanical Systems) is a technology that is used to incorporate sensors, actuators, microstructures, and circuits on chips by using a combination of various technologies with semiconductor process. MEMS are also used in robotics and mechatronics since they can provide compact, low-cost functional co...
In 1960s, Dr. Isemi Igarashi of Toyota Central R&D Labs., Inc. in Japan developed a semiconductor pressure sensor of piezo-resistance type. In 1980s, the pressure sensors were used to control automobile engines to clear exhaust gas regulations and thus contributed to solving environmental issues. In 1990s, semiconduct...
For smartphones, a microphone, an acceleration sensor, and a gyro sensor are used in user interface, and a film bulk acoustic wave resonator (FBAR) is used in a wireless communication filter. For projectors, the built-in circuit of a mirror array system is used to move mirrors placed in an array. After the development...
MEMS are also widely used in medical and biological fields, such as blood pressure measurement. Esashi began research on a semiconductor ion sensor ISFET (ion sensitive field effect transistor) in 1971. ISFET detects ion concentration in electrolyte by exposing the insulating film of an insulated gate transistor to th...
In addition, MEMS are used for production inspection and scientific instrument, including scanning probe microscopes (SPMs), which observe atoms using extremely small nano-probes, and probe cards that simultaneously test several integrated circuits on a wafer using aligned probes.
When he was an associate professor, Esashi improved the prototyping facility that he made when he was a student and made a large scale integrated circuit (LSI). After he became a professor, he accepted researchers from more than 130 companies and developed MEMS using the prototyping facility to develop a product throu...
After he retired from the university, he developed a “prototype coin laundry,” which enables companies to do develop without having their own prototyping facility. The prototype coin laundry is a system where engineers can use the prototyping facility to develop devices, and the system has been managed by successors. ...
Finally, we would like to thank authors who submitted papers to this Special Issue on MEMS for Robotics and Mechatronics as well as those who were involved in editing and reviewing the papers. We sincerely hope for further development in this field of research.Fabrication of ultra-high energy and power asymmetric supe...
Two-dimensional (2D) atomically thick materials, graphene oxide (GO) and layered molybdenum disulfide (MoS2) nanosheets have been potentially investigated as novel energy storage materials due to their unique physicochemical properties. The present manuscript describes a facile binder-free approach to fabricate large-s...
The DNA sequences of organisms are becoming available at an increasing rate and the biological information derived from the genome sequence data has been proven to be very useful in improving our understanding of cellular regulatory patterns. Detection of transcription factor binding sites in the promoter regions of ge...
In this study, the formation mechanism of C2 oxygenates and ethanol from syngas on Fe-decorated Cu bimetallic catalyst was investigated using density functional theory (DFT) calculations together with microkinetic modeling. The results showed that CH2 was the most favored monomer among all the CHx (x = 1-3) species ove...
Every year in India, most of the car accidents are occurs and affects on number of lives. Most of the road accidents are occurs due to driver’s inattention and fatigue. Drivers require to focus on different circumstances, together with vehicle speed and path, the separation between vehicles, passing vehicles, and poten...
The efficacy of reanastomosis was evaluated in 30 patients with obstructive azoospermia, including 19 postvasectomy cases; 7 cases complicating inguinal herniorrhaphy; 2 cases with a characterized isolated congenital anomaly; 1 case of Young's syndrome; and 1 case with an unknown, possibly congenital cause. In the post...
Retinoids (vitamin A and related molecules) are biologic agents that have demonstrated, in preclinical and clinical models, potent activity in the prevention and treatment of a variety of malignancies. Presented in this article is a review of recent clinical studies and correlative laboratory findings that advance our ...
Introduction: Testicular adrenal rest tumors (TART) are a known consequence for males with classical congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. TART are associated with potential infertility in adults. However, little is known about TART in very young males with CAH. Objective: We assessed t...
We have studied the optically compensated splay (OCS) mode applied to polymer stabilization technique using polymerization of reactive mesogen (RM) to reduce or eliminate critical voltage, setting voltage, and phase transition time from bend to splay state. The pretilt angle of almost vertically aligned liquid crystal ...
In this paper, we propose a novel frequency-tunable ${V}$ -band radial-line backward-wave oscillator (BWO). It operates in two high-order modes (i.e., TM02 or TM03 modes) so as to achieve a high power capacity, the reflector of which can effectively reduce the microwave leakage from the radial slow wave structure (SWS)...
The newly introduced noninvasive myocardial work analysis could potentially be beneficial in predicting the best timing for aortic valve replacement as well as clinical outcomes in patients with high grade aortic valve stenosis (AS), which is the leading valvular disease in the modern aging society. However, to date t...
In this pilot study, we aimed to apply myocardial work analysis in patients with increased LV afterload due to severe AS and to investigate the differences of myocardial work parameters in patients with different AS entities. In addition, we analyzed the early changes of myocardial work after the afterload reduction b...
We retrospectively studied echocardiographic data of 28 consecutive patients with severe AS before and 7 days after TAVR. Global Work Index (GWI), Global Constructive Work (GCW), Global Wasted Work (GWW) and Global Work Efficiency (GWE) were calculated using commercially available software based on noninvasive pressur...
From the included patients (mean age 76 ± 10 years) 13 were classified as having normal flow (NF) severe AS, 8 had low flow low gradient (LFLG) and 7 paradoxical low flow low gradient (PLFLG) AS. GWI and GCW were significantly lower in patients with LFLG AS compared to patients with NF or PLFLG AS (936 ± 528 mmHg% vs....
In this pilot study we applied the adapted myocardial work analysis in patients with increased afterload due to severe AS. We have shown that GCW and GWI are significantly higher in patients with NF AS when compared to LFLG and PLFLG AS. The differences between the groups persisted early after TAVR in spite of signifi...
The physics of pulling polyproteins: a review of single molecule force spectroscopy using the AFM to study protein unfolding
One of the most exciting developments in the field of biological physics in recent years is the ability to manipulate single molecules and probe their properties and function. Since its emergence over two decades ago, single molecule force spectroscopy has become a powerful tool to explore the response of biological mo...
e14580 Background: Survival of patients with advanced epithelial ovarian cancer (EOC) with initial suboptimal debulking surgery (residual disease (>1 cm) and those with recurrent EOC is poor. We used EGFR inhibitor gefitinib for maintenance and analyzed data on safety and toxicity.
METHODS
Between Nov. 2004 and Dec. 2008, Patients who achieved complete response (CR) following six cycles of paclitaxel and carboplatin received gefitinib as (Group I). Similarly, patients with recurrent EOC who achieved CR following six cycles of salvage CT received gefitinib (Group II). Both groups received gefitinib 250 mg...
RESULTS
A total of 48 patients (median age 47 years, range 23 to 63) have been recruited. Group I: 17 subjects and Group II 31 patients (1st relapse- 13, 2nd- 9, 3rd -6 & 4th relapse in 3 patients). The mean duration of gefitinib treatment is 8.77 months (Gp-I: 14.4 months, Gp-II: 5.68 months). Toxicity was mainly in the form ...
CONCLUSIONS
Gefitinib was tolerated well with mild toxicities limited to skin and GIT. Correlations between EGFR expressions vs. response may help to identify patients likely to benefit from gefitinib therapy. No significant financial relationships to disclose.The Houston Vision Assessment Test (HVAT): an assessment of validity
PURPOSE. Cataract surgery is one of the most successful procedures in medicine, and outcome is typically measured by a single factor – improvement in visual acuity. Health-related functional outcome testing, which quantifies the patient's self-reported perception of impairment, can be integrated with objective clinical...
Welfare history has not generally been recognized as an identifiable field of study, in part owing to problems of documentation and method. Historians of welfare, moreover, have tended to neglect important themes: the impact of policies and programs on the lives of recipients, for example; the role of family and inform...
ABSTRACT Inclusive education (IE), as a global movement, has been part of many nations’ policy agendas. As the global ideas travel across borders, the meaning of this term has taken various forms in local and national discourses. Thus, this study examines teachers’ conceptualizations and experiences of IE for students ...
OBJECTIVE
To evaluate the value, unit cost and medical effectiveness of providing specialized obstetric and gynecologic care far forward, at echelon III, the combat support hospital (CSH), in the operating theater of Afghanistan during Operation Enduring Freedom (OEF), rotation 5.
STUDY DESIGN
Between April 2004 and September 2004, records were reviewed from the outpatient gynecology clinic at Bagram Air Field (BAF), in Afghanistan, through an approved protocol request. Cohort analysis was performed on all gynecologic patients. Significant differences in distribution of clinical factors were determined by St...