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A human keratinocyte cell line was established by transfecting neonatal foreskin keratinocytes of a Chinese with human papillomavirus (HPV) 16 DNA. As evidenced by the prolonged life span, the clone formation from a single cell, the piling up after prolonged culturing without passage and the chromosomal aneuploidy, thi...
A Silicon interposer with through silicon via (TSV) has become important key components of 3D integration. It is used as an intermediate carrier and a wiring device for IC components like logics, memories, sensors, and so on. Due to wiring with custom design on front and back side, a TSV interposer enables to adapt the...
A key technical challenge in performing 6D object pose estimation from RGB-D image is to fully leverage the two complementary data sources. Prior works either extract information from the RGB image and depth separately or use costly post-processing steps, limiting their performances in highly cluttered scenes and real-...
In the initial phases of angiogenesis, endothelial cells must degrade and cross the vessel basement membrane, as do tumor cells during invasion and metastasis formation. Various metalloproteinases have been implicated in tumor cell invasion, in particular MMP-2 (72 kDa collagenase IV, gelatinase A), which has been demo...
This paper introduces empirical researchers to recent advances in causal inference and stresses the paradigmatic shifts that must be undertaken in moving from traditional statistical analysis to causal analysis of multivariate data. Special emphasis is placed on the assumptions that underly all causal inferences, the l...
IntroductionVitamin D is an important neurosteroid hormone with diverse mechanisms through which it can affect brain development and function, but research on its use in treating autism has been limited. Patients and methodsThis was designed as a prospective case–control 6-month study. It involved 21 children with auti...
The pandemic is a distressing time for academia. The past 24 months have caused a deeper rift between learning and teaching. Online classes have become necessary overnight, but the transition was not smooth and productive. Moreover, educating students with speech and hearing disabilities online is not similar to those ...
Ultrasound is used as the wave source for the sound velocity measurement experiment. Ultrasonic wave is used to form standing wave in the reflection interval, the position of two adjacent wave anti nodes is used to determine the half wavelength, and the sound velocity in the experimental state is measured. The specific...
For centuries, German-speaking culture has been drawn to Asian philosophy from Persia to India to China. Moreover, since Plato's purported stay in Egypt and his introduction to Indian philosophy and with Buddhist monks known since Hellenic times, the reception of Eastern thought can be traced throughout the history of ...
Genetic and environmental cues shape the evolution of the B cell Ig repertoire. Activation-induced cytidine deaminase (AID) is essential to generating Ig diversity through isotype class switching and somatic mutations, which then directly influence clonal selection. Impaired B cell development in AID-knockout mice has ...
The terms under which Programa Cuyo would function and its financing were negotiated in late 1961 and the first half of 1962. The parties to that negotiation were representatives of the Economics Department of the University of Chicago (principally Professor Arnold Harberger), the Rector of National University of Cuyo ...
Perivascular cells or fluorescent granular perithelial cells of the central nervous system are newly recognized members of monocyte/macrophage populations. In this study a monoclonal antibody, GP‐3, that labels proteinous lysosomal antigen of human perivascular cells, has been established. It selectively label the cell...
A watershed moment has been reached in the by now long-running saga of the treatment of hypertension with catheter-based renal nerve ablation, with the recent Lancet publication of three positive, sham-controlled studies [1–3]. Ambulatory blood pressure (BP) was similarly, and materially lowered in the SPYRAL HTN-OFF M...
Historical trends of infant mortality (IM) in the Soviet Union are reviewed with special emphasis on the methods of collecting and reporting statistical data. In 1987, the IM (per 1000 live births) was 25.4; with respect to this index, the USSR was in the 60th place among other countries. Prior to October Revolution (...
Mutual Companies – A Viable Financing Solution in Times of Crisis
Mutual companies along with other microfinance institutions meet an increasing demand for financial services and financial education in Romania. Considering the fact that these companies are non-profit and are based on mutuality, they can be classified as social enterprises – entities which have drawn more and more att...
a more general level, the chronological organization of the documents in Part One leaves readers with the enormous task of reading through all of them to be sure to find what interests them. Very important documents, such as Cornies’ report on his activities for 1838 (151–56), his detailed description of the administra...
How to study more efficiently and maintain the lasting memory of knowledge has long been a contentious hot focus, particularly in the education of Internet era such as the massive open online Courses. Recently, many researchers have pointed out that studying and remembering have good spacing effect, and proposed variou...
Post-translational modification of proteins plays critical roles in regulating structure, stability, localization, and function. Sulfation of the phenolic side chain of tyrosine residues to form sulfotyrosine (sTyr) is a widespread modification of extracellular and integral membrane proteins, influencing the activities...
Retinoic acid, a hormone biosynthesized from retinol, controls numerous biological systems by regulating eukaryotic gene expression from conception through death. This work reports the cloning and expression of a liver cDNA encoding a microsomal retinol dehydrogenase (RoDH), which catalyzes the primary and rate-limitin...
In this paper we analyze the fraction of non‐disjunction in Meiosis I assuming reference (non‐informative) priors. We consider Jeffreys's approach to built a non‐informative prior (Jeffreys's prior) for the fraction of non‐disjunction in Meiosis I. We prove that Jeffreys's prior is a proper distribution. We perform Mon...
Kaposi sarcoma is a rare adult neoplasm and there has been no certain consensus on standard treatment, either local or systemic. Radiotherapy is an effective, suitable treatment modality. Between 1996 and 2016, patients who were diagnosed with Kaposi sarcoma and referred to our clinic for radiotherapy were included in ...
Introduction/Background Autopsy studies report inguinal metastasis in up to 3% of patients with advanced ovarian cancer. Metastasis occurs via a minor lymphatic drainage pathway running through the round ligament of the uterus toward the inguinal region. Postoperative complications after inguinal surgery performed thro...
This paper describes the results of an observational study of the information seeking behaviour of Members of Parliament. It is argued that political life functions on a flow of information and that information itself is a prime resource. The study sought to determine the characteristics that impact upon the manner in ...
The article outlines the production of fibrous materials, discloses energy production targets for mineral wool items production, scrutinizes specific features of cupola process. Besides, the article presents the experimental research of mineral wool cupola process. Thus, the article describes the design of a cupola fur...
This paper will describe an ongoing collaboration between the authors to combine the Director Musices and Conductor programs in order to achieve a more expressive and socially interactive performance of a midi file score by an electronic orchestra. Director Musices processes a “square” midi file, adjusting the dynamics...
Presence of the past” is one of the basic principles of postmodern architecture and has been interpreted in many ways. A multitude of architects turned towards the past and found their references in heritage elements. While some inspired ideas from historic architecture, others copied or re-used elements and vocabulary...
The study was concerned with patterns of stage IV lymphogranulomatosis (Hodgkin's disease) recurrence as well as factors affecting it. A combined therapy relying mostly on MOPP scheme was used. Out of 109 children treated, primary complete remission was obtained in 78 (71.6%). However, remission continued throughout th...
The metabolism of 3H-catecholamines after i.p. injection of 3H-tyrosine was studied in the heart and adrenals of spontaneously hypertensive (SHR) and normotensive Wistar (NCR) rats at rest and following running stress. In the heart of 8-week-old NCR a sharp stress-induced increase of the levels of 3H-A and 3H-DA with a...
Background
Gastric cancer is a common malignant tumor. The aim of the present study was to analyze the application value of serum pepsinogen (PG), carbohydrate antigen 72-4 (CA72-4), and gastrin-17 (G-17) detection in the screening, diagnosis, and evaluation of early gastric cancer.
Methods
In total, 122 patients with gastric cancer treated in our hospital from January 2018 to January 2021 were selected as the gastric cancer group and subdivided into the early gastric cancer (group A) and advanced gastric cancer (group B) groups. Sixty-five patients with benign gastric disease treated in the same hospital...
Results
G-17, PGI, and PGI/PGII levels in the gastric cancer group were significantly lower than those in the healthy group, and CA72-4 was significantly higher than that in the healthy group (P<0.05), but there was no significant difference in PGII between the 2 groups (P>0.05). G-17, PGI, and PGI/PGII levels in groups A and ...
Conclusions
Serum PG, CA72-4 combined with G-17 detection has high sensitivity and specificity in the screening and diagnosis of early gastric cancer, and has high clinical application value.The Status of Wound Care Education.
This month’s issue begins with two articles that focus on the current state of wound care education. The old paradigm for wound care training is outdated and does not match the substantial increases in technology and therapeutic options currently, and soon to be, available. The wound care market is estimated to be a 15...
The FLAC3D was used to the fluid-solid coupling numerical simulation of considering the initial state of unsaturated to soil for the deep foundation pit engineering under different rainfall infiltration conditions. By comparing the bending moment, the shearing stress and internal forces of support under the infiltratio...
The authors describe a new angiographic catheter, which delivers equal flow rates through the side holes and reduced flow through the end hole compared with conventional catheters. Computer analysis of catheter-flow models revealed that placement of larger side holes proximally and smaller side holes distally produces ...
Abstract This article stands as a response to Goodwin-Hawkins and Dawson’s (2018) article “Life’s End: Ethnographic Perspectives” which was published in this journal as an Introduction to a Special Issue of ethnographies about end of life. We address three interwoven fallacies promoted in “Life’s End.” First, we begin ...
The three-dimensional structure of high-performance fiber bundles are of paramount importance for their study in lateral compression mechanism. Modeling of their true morphologies is still fields of focus research, yet to be exhausted. In this paper, ANSYS were utilized to develop three-dimensional numerical model of f...
This paper provides reflections on my academic career in kinesiology and public health from an autobiographical perspective. Themes include the importance of movement and physical activity in my development and career choices, a recognition of the importance of physical activity for health outcomes, experiences in stud...
We report a case of double cancer of the liver and esophagus, an extremely rare condition that can be very difficult to treat. A tumorous lesion was pointed out in segment 6 of the liver of a 69-year-old man under treatment for liver cirrhosis. Abdominal computed tomography and angiography revealed a hepatocellular car...
The activity of the mitochondrial glycerol phosphate dehydrogenase (EC 1.1.99.5), the enzyme unique to the glycerol phosphate hydrogen shuttle, was measured in normal human tissues and tumors and compared with the activity of succinate dehydrogenase, another enzyme that transfers electrons to ubiquinone at site II of t...
The last few years have seen a burgeoning interest in clinical performance measurement and accountability. At the national level, the Federal Government plans to measure public hospital performance and if found wanting, based on yet-to-be-declared benchmarks, the States risk having the running of their hospitals taken ...
This paper presents a model showing that accounting conservatism affects creditor coordination when the borrowing firm is in financial distress. There are two effects. First, accounting conservatism tends to reduce dividend payments and to keep assets within the firm (dividend restriction effect). Second, it biases exp...
CONDITIONS affecting the shoulder are common causes of thoracic limb lameness in the dog. Some diseases such as osteochondritis dissecans have been well documented, while many tendon and ligament injuries have received relatively little attention. Diagnosis of the latter is difficult and their management remains a chal...
By use of a friction drive, two motors can be used alternately to reproduce a three-degree-of-freedom wrist manoeuvre. The algorithms required to achieve this are developed. In particular the efficiency of the resolution of the desired rotation is defined and simple approximations are derived for optimum operation, tha...
We have studied the electrical degradation of RF-power PHEMTs by means of in situ 2-D light-emission measurements. Electroluminescence originates in the recombination of holes that have been generated by impact ionization. The local light intensity, thus, maps the electric-field distribution at the drain side of the de...