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High levels of dietary fat enhance the severity of certain cancers, obesity, and cardiovascular diseases in susceptible individuals usually after prolonged exposure. We have been developing methods for identifying and characterizing genes regulated by the level of dietary fat for the purpose of determining their role i... |
Aim: to evaluate the level of knowledge about dental trauma injury and first aid skills among teachers of educational institutions by means of a survey in Moscow, Russia. Materials and methods: A questionnaire, consisting of 4 parts and including 20 questions, including questions from the category of own experience in ... |
A A Vldous Huxley's imagination, laboring against the fact of cancer, created in his last days a Utopian island called Pala. Pala's inhabitants are freed from mind -forged manacles through a liberating education. Though the regents of this world eventually destroy the island, "the fact of enlightenment remained." "You'... |
This paper presents two clustering algorithms based on α-divergence between memberships and variables that control cluster sizes: one is for spherical data and the other for categorical multivariate data. First, this paper shows that a conventional method for vectorial data can be interpreted as the regularization of a... |
OBJECTIVE |
to determine the frequency of major somatic mutations in the JAK2, MPL and CALR genes in the genomeof patients with Ph-negative myeloproliferative neoplasms that occur in individuals who have been exposed to ionizing radiation as a result of the Chornobyl accident. |
MATERIALS AND METHODS |
Molecular genetic analysis of genomic DNA samples isolated from blood was performed in90 patients with Ph-negative myeloproliferative neoplasia (MPN) with a history of radiation exposure and 191patients with spontaneous MPN utilizing allele-specific polymerase chain reaction (PCR). |
RESULTS |
The presence of major mutations in the genes JAK2, CALR and MPL was revealed in patients with MPN witha history of radiation exposure with a frequency 58.9 % (53 of 90), 12.2 % (11 of 90), and 0 % respectively, and without exposure with frequency 75.4 % (144 of 191), 3.1 % (6 out of 191) and 1.6 % (3 out of 191) respec... |
CONCLUSIONS |
Genomic research of patients with Ph-negative MPN revealed features of molecular genetic damage inthose patients who were exposed to IR as a result of the Chornobyl accident and those with spontaneous MPN. Thedata obtained by determining of JAK2, MPL and CALR genes mutational status in the genome of patients with MPN i... |
The overall energy efficiency of a refinery is highly affected by the performance of its crude preheat train which is often severely hindered by fouling. Over the last twenty years, significant efforts have been made to develop design methods for crude preheat exchangers that use models describing the dynamics of the f... |
IoT is a man-made technology conceptualized by intelligent virtual objects, which capable of knowing all things and allows the devices around themselves to interact automatically without human control. Every year, the number of IoT devices usage is exponentially increasing and estimated as much as 75.44 billion devices... |
Layer-by-layer adsorption of protonated poly(allylamine) (PAH) and deprotonated poly(N,N-dicarboxymethylallylamine) (PDCMAA) yields thick films with a high density of iminodiacetic acid (IDA) ligands that bind metal ions. When film deposition occurs at pH 3.0, PAH/PDCMAA bilayer thicknesses reach 200 nm, and Cu(2+) bin... |
Current knowledge about the interaction between GH and its receptor suggests that the molecular heterogeneity of circulating GH may have important implications for growth. The aim of this study was to investigate the proportion of circulating non-22-kDa GH isoforms in prepubertal children with short stature (height les... |
Novel photosensitive insulating materials comprising of organic silsesquioxane (OSQ) have been developed. The OSQ had the high photosensitivity, insulating performance, transparency, and heat resistance required for a passivation layer of semiconductors in thin-film-transistor liquid crystal displays (TFT-LCDs). A pass... |
The results of an experimental and ONIOM-based computational investigation of the mechanism and the origins of enantioselectivity in the asymmetric synthesis of alpha-amino phosphonates by an enantioselective hydrophosphonylation of imines catalyzed by chiral Brønsted acids are reported. It was found that the enantiose... |
Poly(2-bromo-5-hexyloxy-p-phenylenevinylene), BHPPV, was electrochemically synthesized in 81% yield. The polymer presented high solubility in organic solvents, in spite of its relatively high molar weight (M w = 80 ooo), and showed to be thermally resistant up to 130 °C. Gas sensors made from thin films of CSA doped BH... |
Aluminum-doped zinc oxide (AZO) is one of the most promising transparent conductive oxide materials for a front electrode in solar cells. In this work, we roughened substrate surface and sputtered AZO films, where the effect of roughness on various AZO properties was investigated. The haze values were largely enhanced,... |
Several frequency bands above 6 GHz are being proposed for next generation wireless systems, and the electromagnetic characteristics of many common construction materials at these frequencies still need to be determined. The knowledge of such characteristics is particularly relevant, especially in relation to the incre... |
PURPOSE |
Although the relationship between optic pits and macular lesions was described nearly a century ago, the pathology and pathogenesis of macular detachment remain unclear. Recent OCT studies have shown schisislike spaces in connection with the disc. None of the hypotheses of pathogenesis proposed so far could have been p... |
CASE REPORT AND THERAPY |
A 32-year-Caucasian woman developed macular detachment associated with an optic pit on her right eye. The vision deteriorated to 24/60. A standard three-port pars plana vitrectomy was performed. After creating a posterior vitreous detachment, all vitreoretinal adhesions were removed carefully. Peripapillary laser coagu... |
CONCLUSIONS |
Besides the exudative component of macular detachment, the vitreoretinal interface seems to play an underestimated role in the pathogenesis of maculopathy associated with optic pits. Tractional forces could explain the delay of macular detachment in young adulthood and the frequency of treatment failure after laser coa... |
An attempt must be made to deal with the emotionally disturbed person in the test area of various social relationships, in order to learn to understand better the "language" of his symptoms. Moreover, Adler, Freud and Lorenz taught us to pay special attention to child development. This paper tries to project sexually d... |
In conceiving her novel Frankenstein , Mary Shelley was influenced by the nascent medical science of the day and by early experiments on electricity. In return, Frankenstein has haunted science ever since. Shelley9s book and subsequent films and plays have become what one author calls "the governing myth of modern biol... |
The discipline of biblical archeology is in a period of reassessment following the death of many of its primary exponents and the assertion by others that Syro-Palestinian archeology is a separate and distinct field of study. In the face of this vigorous declaration of independence, biblical archeology must certainly r... |
Two new B1 receptor antagonists, [Hyp3,Thi5,DTic7,Oic8]desArg9-BK and DArg[Hyp3,Thi5,DTic7,Oic8]desArg9-BK were tested in vitro on the rabbit jugular vein and the guinea pig ileum (preparations containing B2 receptors) and on the rabbit aorta (preparation containing B1 receptors) for pharmacological characterization. T... |
The relationship of postmenopausal hormone replacement therapy to lipoproteins was assessed in a cohort of 211 healthy premenopausal women followed during the menopausal transition. Both estrogen and estrogen-progestogen users had minimal increases in low-density lipoprotein (LDL) cholesterol levels, whereas non-users ... |
Abstract Background: The increase in population life expectancy in developed economies is also reflected in the aging of the workforce; therefore, enterprises should create an appropriate work environment for all employees, emphasizing the older ones. Objectives: The major objectives of this paper are to establish the ... |
The objective of the present study was to evaluate the effect of a hydrocolloid dressing on second intention wound healing in cats. Two full-thickness skin wounds, measuring 2 × 2 cm, were created on both sides of the dorsal midline of 10 cats; bilaterally, one randomly selected wound was bandaged with a hydrocolloid d... |
Electronic fetal monitoring (EFM) is used for the majority of births that occur in the United States. While there are indications for use of EFM for women with high-risk pregnancies, its use in low-risk pregnancies is less evidence-based. In low-risk women, the use of EFM is associated with an increased risk for cesare... |
The distance-3 graph S of the Biggs-Smith graph S is shown to be both a connected edge-disjoint union of 102 tetrahedra, (copies of K4), and a union of 102 cuboctahedra, (copies of L(Q3)), with no two such cuboctahedra having a common chordless 4-cycle. Moreover, S is shown to have a C-ultrahomogeneous property for C =... |
The purpose of this research was to reading comprehension in the linguistic expression of high school students of the "Eidan Abel Erique Cercado" educational unit. The results obtained from the research are shown, applied to teachers and students through a survey, as a way to publicize the link between the strategies t... |
Optimization of the carrier concentration by doping/alloying is a key prerequisite for improving thermoelectric performance. In reality, it is, however, challenging to identify effective dopants in some specific systems. Herein, we discovered that Y doping significantly reduced the carrier concentration, enhanced the p... |
they should have volunteered is that they were already close to death in any case, is the number of their children of any significance. The point here, as in Ant., is the uniqueness and irreplaceability of the relation for whose benefit one is, or is not, acting, and I submit that Alcestis makes it because it is made i... |
Recombinant OSU VP4 protein, and outer capsid antigen of porcine rotavirus, was purified to a high level from the spent broth of baculovirus-infected Spodoptera frugiperda insect cells. Initial clarification of the broth with a 0-60% ammonium sulfate cut retained 93% of the total VP4. Q-sepharose ion exchange chromatog... |
Factors in the fermentation-inhibition test for the measurement of growth-inhibiting antibody in serum to Mycoplasma pneumoniae were studied. The fermentation-inhibiting antibody titer, as read on the day when the color of the control cup without serum had just changed to yellow, was constant among inoculum dilutions o... |
In this study, the effect of different amounts of graphene oxide (GO) nanoparticles on the desalination performance of cellulose acetate (CA) reverse osmosis mixed matrix membranes has been investigated. To investigate the interactions between different parameters and optimize the membrane performances, response surfac... |
The paper presents a new algorithm for adaptive classification of sleep stages using multimodal data recorded in the sleep laboratory during overnight polysomnography records. The proposed method includes the learning process applied for the set of individuals with their sleep stages classified by an experienced neurol... |
Peptide antibiotics are known to contain non-protein amino acids, D-amino acids, hydroxy acids, and other unusual constituents. In addition they may be modified by N-methylation and cyclization reactions. Their biosynthetic origin has been connected in many cases to an enzymatic system referred to as the 'thiotemplate ... |
In this report, the evidence, mechanisms, and rationale for the practice of artificial cranial deformation (ACD) in ancient Peru and during Akhenaten's reign in the 18th dynasty in Egypt (1375-1358 BCE) are reviewed. The authors argue that insufficient attention has been given to the sociopolitical implications of the ... |
There are many factors which affect nurse satisfaction level. This study aimed to identify the impact of nurse scheduling management on job satisfaction in Army hospital. This study used cross-sectional approach with total sample of 102 nurses. The sample was selected through stratified random sampling method with incl... |
Using a discursive therapy approach that draws heavily from collaborative therapy, the author of this article demonstrates how the therapist (author) used the interdependent philosophical assumptions of not-knowing, being public, and honoring a client's story as a means to counteracting social inequalities experienced ... |
We review our recent work on three-dimensional chiral photonic crystals. High-quality polymeric three-dimensional spiral and layer-by-layer photonic crystals are fabricated via direct laser writing. Polarization stop bands for circularly polarized light are observed, leading up to a suppression of a factor 52 for one c... |
This study aims to reveal significant factors which affect automobile sales and estimate the automobile sales in Turkey by using Artificial Neural Network (ANN), ARIMA, and time series decomposition techniques. The forecasting model includes automobile sales, automobile price, Euro and Dollar exchange rate, employment ... |
The potential for performance improvements through sensor fusion is explored for two electro-optical (EO) imaging sensors: a passive thermal IR camera and an active polarimetric system. Tests of decision-level fusion using a small data set (roughly 60 mine signatures) suggest that a significant performance improvement ... |
Treatment of human placental brush-border membrane vesicles with tyrosyl group-specific reagents, N-acetylimidazole, 7-chloro-4-nitrobenzo-2-oxa-1,3,-diazole and tetranitromethane, inhibited NaCl gradient-driven serotonin uptake in these vesicles without affecting vesicle integrity. The concentrations of these reagents... |
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