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sense_dimmed_sleep/s41598023340024_87_0.txt
## Discussion
sense_dimmed_sleep/s12931022021413_222_0.txt
Microarousal index
sense_dimmed_sleep/s41598023340024_144_0.txt
5. Coren, S. Prediction of insomnia from arousability predisposition scores: Scale development and cross-validation. _Behav. Res. Ther._ **26** (5), 415–420. [ https://doi.org/10.1016/0005-7967(88)90076-9 ](https://doi.org/10.1016/0005-7967\(88\)90076-9) (1988).
sense_dimmed_sleep/s41598023340024_187_2.txt
2CC&author=Cheng%2CW)
sense_dimmed_sleep/s12931022021413_275_1.txt
20sleep%20apnea%3A%20supine- predominant%20and%20supine- isolated&journal=Clin%20Neurophysiol&doi=10.1016%2Fj.clinph.2015.06.009&volume=127&issue=1&pages=565-570&publication_year=2016&author=Kim%2CKT&author=Cho%2CYW&author=Kim%2CDE&author=Hwang%2CSH&author=Song%
sense_dimmed_sleep/s12931022021413_327_0.txt
[ Article ](https://doi.org/10.5664%2Fjcsm.2172) [ PubMed ](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=23066376) [ PubMed Central ](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459210) [ Google Scholar ](http://scholar.google.com/sch
sense_dimmed_sleep/s12931022021413_265_1.txt
http://scholar.google.com/scholar_lookup?&title=Increased%20incidence%20of%20coronary%20artery%20disease%20in%20sleep%20apnoea%3A%20a%20long- term%20follow- up&journal=Eur%20Respir%20J&doi=10.1183%2F09031936.06.00107805&volume=28&issue=3&pages=596-602&publication_
sense_dimmed_sleep/s12931022021413_71_1.txt
3#ref-CR36 "Guan J, Yi H, Zou J, Meng L, Tang X, Zhu H, et al. Distinct severity stages of obstructive sleep apnoea are correlated with unique dyslipidaemia: large-scale observational study. Thorax. 2016;71\(4\):347–55. https://doi.org/10.1136/thoraxjnl-2015-207403
sense_dimmed_sleep/s41598023340024_181_1.txt
F19.suppl_9.s136&volume=19&issue=9%20SUPPL.&pages=136-143&publication_year=1996&author=Krieger%2CJ&author=Kurtz%2CD&author=Petiau%2CC&author=Sforza%2CE&author=Trautmann%2CD)
sense_dimmed_sleep/s12931022021413_443_47.txt
LjEuNjUgMS40NC4zNi4zMy44Mi41IDEuMzguNS4zIDAgLjU4LS4wNC44NC0uMTMuMjUtLjA5LjUxLS4yMS43Ni0uMzdsLjU0IDEuMDFjLS4zMi4yMS0uNjkuMzktMS4wOS41M3MtLjgyLjIxLTEuMjYuMjFjLS40Ny
sense_dimmed_sleep/s12931022021413_99_0.txt
[ Full size image ](/articles/10.1186/s12931-022-02141-3/figures/2)
sense_dimmed_sleep/s41598023340024_246_0.txt
[![Check for updates. Verify currency and authenticity via CrossMark](data:image/svg+xml;base64,PHN2ZyBoZWlnaHQ9IjgxIiB3aWR0aD0iNTciIHhtbG5zPSJodHRwOi8vd3d3LnczLm9yZy8yMDAwL3N2ZyI+PGcgZmlsbD0ibm9uZSIgZmlsbC1ydW
sense_dimmed_sleep/s12931022021413_110_1.txt
sleep apnea, _POSA_ positional obstructive sleep apnea, _si-POSA_ supine-isolated positional obstructive sleep apnea, _sp-POSA_ supine-predominant positional obstructive sleep apnea
sense_dimmed_sleep/s12931022021413_438_0.txt
Clinical and Sleep Characteristics of All Subjects (n = 7110).
sense_dimmed_sleep/therelationshipbetwe_69_0.txt
o He/She may be over-responsive to tactile input
sense_dimmed_sleep/s41598023340024_98_1.txt
, A57–A58. https://doi.org/10.1093/sleepadvances/zpac029.156
sense_dimmed_sleep/nonobesepatientswith_72_0.txt
* Placeholder * CloudPAT Servers * [ USA ](https://cloudpat.precisemd.com/) * [ UK ](https://cloudpatuk.precisemd.com/) * [ EU ](https://cloudpateu.precisemd.com/) * [ HEALTHCARE PROFESSIONALS ](https://www.itamar-medical.com/professionals/) * Products * • Home Sleep Apnea Testing * [ WatchPAT ®️ 300
sense_dimmed_sleep/s41598023340024_53_0.txt
https://doi.org/10.5664/jcsm.6470
sense_dimmed_sleep/therelationshipbetwe_137_0.txt
The Center for Connection, 3030 E. Colorado, Suite 214, Pasadena, California, 91107, USA [ info@thecenterforconnection.org ](mailto:info@thecenterforconnection.org)
sense_dimmed_sleep/s12931022021413_411_0.txt
8. Jian Guan
sense_dimmed_sleep/s12931022021413_359_0.txt
[ Article ](https://doi.org/10.5664%2Fjcsm.7112) [ PubMed ](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=29734986) [ PubMed Central ](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940432) [ Google Scholar ](http://scholar.google.com/sch
sense_dimmed_sleep/nonobesepatientswith_33_0.txt
7\. Frey WC, Pilcher J (2003) Obstructive sleep-related breathing disorders in patients evaluated for bariatric surgery. Obes Surg 13(5):676–683. [ https://doi.org/10.1381/096089203322509228 ](https://doi.org/10.1381/096089203322509228)
sense_dimmed_sleep/s41598023340024_246_40.txt
ktLjI0LjgxLS40NSAxLjI4LS42My40Ny0uMTcuOTktLjI2IDEuNTQtLjI2Ljg2IDAgMS41MS4yNSAxLjkzLjc2cy42MyAxLjI1LjYzIDIuMjF2NC4wN2gtMS4zMmwtLjEyLS43NmgtLjA1Yy0uMy4yNy0uNjMuND
sense_dimmed_sleep/s41598023340024_246_11.txt
IDEuMTQuNSAyLjAydjQuMzFoLTEuNjF2LTQuMWMwLS41Ny0uMDgtLjk3LS4yNS0xLjIxLS4xNy0uMjMtLjQ1LS4zNS0uODMtLjM1LS4zIDAtLjU2LjA4LS43OS4yMi0uMjMuMTUtLjQ5LjM2LS43OC42NHY0L
sense_dimmed_sleep/s12931022021413_19_0.txt
* 11 Citations
sense_dimmed_sleep/therelationshipbetwe_29_0.txt
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sense_dimmed_sleep/nonobesepatientswith_2_8.txt
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sense_dimmed_sleep/s12931022021413_333_2.txt
_year=2014&author=Edwards%2CBA&author=Eckert%2CDJ&author=McSharry%2CDG&author=Sands%2CSA&author=Desai%2CA&author=Kehlmann%2CG)
sense_dimmed_sleep/s41598023340024_306_0.txt
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sense_dimmed_sleep/s41598023340024_164_0.txt
15. Gleeson, K., Zwillich, C. W. & White, D. P. The influence of increasing ventilatory effort on arousal from sleep. _Am. Rev. Respir. Dis._ **142** (2), 295–300. [ https://doi.org/10.1164/ajrccm/142.2.295 ](https://doi.org/10.1164/ajrccm/142.2.295) (1990).
sense_dimmed_sleep/nonobesepatientswith_79_0.txt
_format_size_ Increase Text
sense_dimmed_sleep/nonobesepatientswith_10_0.txt
The anatomical predisposition factors are present in all patients (in 30% of patients without other factors). In 70% of cases, there are 1 or more associated _non_ -anatomical pathophysiologic factors. This is responsible for a different phenotype of the disease. 2
sense_dimmed_sleep/therelationshipbetwe_60_0.txt
*Getting up or waking up at night on a regular basis
sense_dimmed_sleep/s12931022021413_258_1.txt
.
sense_dimmed_sleep/s12931022021413_89_0.txt
## Results
sense_dimmed_sleep/s12931022021413_377_0.txt
## Funding
sense_dimmed_sleep/nonobesepatientswith_4_0.txt
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sense_dimmed_sleep/therelationshipbetwe_20_0.txt
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sense_dimmed_sleep/s12931022021413_307_0.txt
[ Article ](https://doi.org/10.3390%2Fjcm8111846) [ PubMed ](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=31684047) [ PubMed Central ](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912255) [ Google Scholar ](http://scholar.google.com
sense_dimmed_sleep/s41598023340024_131_0.txt
\(2022\)."). However, most included subjects had severe OSA.
sense_dimmed_sleep/nonobesepatientswith_2_1.txt
/) * [ EndoPAT®️X ](https://www.itamar-medical.com/professionals/endopat-x/) * [ PAT®️ Technology ](https://www.itamar-medical.com/pat-peripheral-arterial-tone-technology/) * Services * • Home Sleep Apnea Testing * [ WatchPAT®️ Direct ](https://www.itamar-medical.com/professionals/watchpat-direct/) * [ WatchPAT®️ Solut...
sense_dimmed_sleep/s12931022021413_257_0.txt
## References
sense_dimmed_sleep/s12931022021413_289_0.txt
[ Article ](https://doi.org/10.5664%2Fjcsm.8752) [ PubMed ](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=32804071) [ PubMed Central ](http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7848932) [ Google Scholar ](http://scholar.google.com/
sense_dimmed_sleep/s12931022021413_36_1.txt
. https://doi.org/10.1016/s2213-2600\(19\)30198-5
sense_dimmed_sleep/s41598023340024_298_0.txt
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sense_dimmed_sleep/s12931022021413_301_1.txt
scholar_lookup?&title=Positional%20obstructive%20sleep%20apnea%20syndrome%20in%20elderly%20patients&journal=Int%20J%20Environ%20Res%20Public%20Health&doi=10.3390%2Fijerph17031120&publication_year=2020&author=Iannella%2CG&author=Magliulo%2CG&author=Lo%20Iacono%2CCAM&author=Bianchi
sense_dimmed_sleep/s12931022021413_443_32.txt
jI0LjMxLjQxLjY4LjUzIDEuMTEuMTMuNDIuMTkuOTEuMTkgMS40NCAwIC41OS0uMDkgMS4xMS0uMjUgMS41Ny0uMTYuNDctLjM4Ljg1LS42NSAxLjE2LS4yNy4zMi0uNTguNTYtLjk0LjczLS4zNS4xNi0uNzIuMj
sense_dimmed_sleep/s12931022021413_293_2.txt
%2CA&author=Berger%2CP&author=Hamilton%2CG)
sense_dimmed_sleep/s41598023340024_40_0.txt
The respiratory arousal threshold (AT) is defined as the level of ventilatory drive that triggers an arousal from sleep at the termination of a respiratory event [ 3 ](/articles/s41598-023-34002-4#ref-CR3 "Edwards, B. A. et al. Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep...
sense_dimmed_sleep/nonobesepatientswith_51_0.txt
I want to receive additional information and marketing material. Your information will be handled according to our [ Privacy Policy ](/itamar- medical-privacy-policy-final-230919-2/)
sense_dimmed_sleep/therelationshipbetwe_74_0.txt
· Wants to sleep next to someone
sense_dimmed_sleep/s12931022021413_49_0.txt
.") ]. Therefore, the prevalence of POSA in ethnic Chinese populations is likely to differ from that in other races. However, there has been only one previous study of Chinese POSA patients, which used single criterion, had a small sample size and limited subgroup analyses, and did not adjust for confounding factors [ ...
sense_dimmed_sleep/s12931022021413_266_0.txt
5. Gottlieb DJ, Punjabi NM. Diagnosis and management of obstructive sleep apnea: a review. JAMA. 2020;323(14):1389–400. [ https://doi.org/10.1001/jama.2020.3514 ](https://doi.org/10.1001/jama.2020.3514).
sense_dimmed_sleep/s12931022021413_84_0.txt
.") ]. Each fulfilled criterion is scored as 1, and a total score ≥ 2 is taken to indicate a low ArTH. This tool is widely used and does not require epiglottic measurements, thus allowing analyses of large retrospective datasets [ 39 , 40 , [ 41 ](/articles/10.1186/s12931-022-02141-3#ref-CR41 "Lee RWW, Sutherland K, ...
sense_dimmed_sleep/s12931022021413_190_0.txt
American Academy of Sleep Medicine
sense_dimmed_sleep/s12931022021413_185_1.txt
may inform the selection of targeted therapy to improve CPAP use. Personalized treatment, such as the use of positional therapy devices, should be considered when treating POSA, and may be beneficial for individuals with poor adherence to CPAP.
sense_dimmed_sleep/s12931022021413_278_0.txt
11. Oulhaj A, Al Dhaheri S, Su BB, Al-Houqani M. Discriminating between positional and non-positional obstructive sleep apnea using some clinical characteristics. Sleep Breath. 2017;21(4):877–84. [ https://doi.org/10.1007/s11325-017-1499-0 ](https://doi.org/10.1007/s11325-017-1499-0).
sense_dimmed_sleep/s41598023340024_48_0.txt
https://doi.org/10.1007/s00127-012-0502-0
sense_dimmed_sleep/s12931022021413_470_0.txt
### Follow BMC
sense_dimmed_sleep/therelationshipbetwe_59_0.txt
*Restlessness or frequent changing of positions
sense_dimmed_sleep/s41598023340024_197_1.txt
%20and%20diagnostic%20missclassification%20of%20obstructive%20sleep%20apnea&journal=Am.%20J.%20Respir.%20Crit.%20Care%20Med.&doi=10.1164%2Frccm.202107-1761OC&volume=205&issue=5&pages=563-569&publication_year=2022&author=Lechat%2CB&author=Naik%2CG&author=Reynolds%2CA
sense_dimmed_sleep/s12931022021413_357_1.txt
20with%20a%20low%20arousal%20threshold&journal=Clin%20Sci%20%28Lond%29&doi=10.1042%2Fcs20100588&volume=120&issue=12&pages=505-514&publication_year=2011&author=Eckert%2CDJ&author=Owens%2CRL&author=Kehlmann%2CGB&author=Wellman%2CA&author=Rahangdale%2CS&author=Y
sense_dimmed_sleep/s12931022021413_119_3.txt
.1186/s12931-022-02141-3#Tab2) ). As BMI increased, the prevalence of POSA decreased (Additional file [ 1 ](/articles/10.1186/s12931-022-02141-3#MOESM1) : Fig. S1), especially in the si-POSA and APOC I groups.
sense_dimmed_sleep/s12931022021413_144_0.txt
.") ].
sense_dimmed_sleep/s12931022021413_160_0.txt
.") ].
sense_dimmed_sleep/s41598023340024_4_0.txt
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sense_dimmed_sleep/s12931022021413_225_0.txt
NC:
sense_dimmed_sleep/s12931022021413_82_1.txt
in patients with obstructive sleep apnea. Am J Respir Crit Care Med. 2014;190\(11\):1293–300.
sense_dimmed_sleep/s12931022021413_167_0.txt
Our patients with a higher mean SaO 2 (> 95%) during sleep and mild-to- moderate OSA were more likely to have POSA. Women with OSA had a higher likelihood of POSA, especially those in the si-POSA and APOC I groups, suggesting that women may benefit more from positional therapy. Although positional therapy alone will ...
sense_dimmed_sleep/s12931022021413_133_0.txt
To our knowledge, this is the first study to analyze the clinical characteristics and ArTH of Chinese POSA patients according to both the CC and APOC criteria, and the prevalence of the disease in a large Chinese sample. More than 1/3 of the OSA subjects met the CC or APOC criteria for POSA, representing a lower preval...
sense_dimmed_sleep/s12931022021413_263_1.txt
olar.google.com/scholar_lookup?&title=Obstructive%20sleep%20apnea%3A%20the%20most%20common%20secondary%20cause%20of%20hypertension%20associated%20with%20resistant%20hypertension&journal=Hypertension&doi=10.1161%2Fhypertensionaha.111.179788&volume=58&issue=5&pages=811-817&publication_year=2011&author=Pedrosa
sense_dimmed_sleep/s41598023340024_301_0.txt
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sense_dimmed_sleep/s12931022021413_250_0.txt
Slow wave sleep
sense_dimmed_sleep/s12931022021413_458_0.txt
* [ Positional obstructive sleep apnea ](/search?query=Positional%20obstructive%20sleep%20apnea&facet-discipline="Medicine%20%26%20Public%20Health") * [ Prevalence ](/search?query=Prevalence&facet-discipline="Medicine%20%26%20Public%20Health") * [ Respiratory arousal threshold ](/search?query=Respiratory%20arousal%20th...
sense_dimmed_sleep/therelationshipbetwe_102_0.txt
o He/She may be over-responsive to visual input
sense_dimmed_sleep/s12931022021413_127_1.txt
OC) were positive predictors of POSA (Table [ 4 ](/articles/10.1186/s12931-022-02141-3#Tab4) ). Table [ 5 ](/articles/10.1186/s12931-022-02141-3#Tab5) shows the results of binary logistic regression analysis of the associations among mean SaO 2 , AHI, and POSA. Compared to AHI ≥ 55/h, mild OSA (5 ≤ AHI < 15/h), modera...
sense_dimmed_sleep/s12931022021413_349_1.txt
](http://scholar.google.com/scholar_lookup?&title=The%20influence%20of%20increasing%20ventilatory%20effort%20on%20arousal%20from%20sleep&journal=Am%20Rev%20Respir%20Dis&doi=10.1164%2Fajrccm%2F142.2.295&volume=142&issue=2&pages=295-300&publication_year=1990&author=Gleeson%2C
sense_dimmed_sleep/s12931022021413_41_0.txt
https://doi.org/10.1007/s11325-021-02346-8
sense_dimmed_sleep/s12931022021413_209_0.txt
CVD:
sense_dimmed_sleep/s12931022021413_182_0.txt
## Current knowledge/study rationale
sense_dimmed_sleep/nonobesepatientswith_72_1.txt
](https://www.itamar-medical.com/professionals/watchpat-300/) * [ WatchPAT®️ ONE ](https://www.itamar-medical.com/professionals/disposable-hsawatchpat-one/) * [ PAT ®️ Technology ](https://www.itamar-medical.com/pat-peripheral-arterial-tone-technology/) * • Endothelial Dysfunction * [ EndoPAT ®️ ](https://www.it
sense_dimmed_sleep/s12931022021413_362_0.txt
53. Eckert DJ. Phenotypic approaches to obstructive sleep apnoea—new pathways for targeted therapy. Sleep Med Rev. 2018;37:45–59. [ https://doi.org/10.1016/j.smrv.2016.12.003 ](https://doi.org/10.1016/j.smrv.2016.12.003).
sense_dimmed_sleep/therelationshipbetwe_107_0.txt
1) Eat dinner early—about 2 ½ hours before bedtime. This will allow for digestion.
sense_dimmed_sleep/s41598023340024_5_0.txt
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sense_dimmed_sleep/s12931022021413_172_0.txt
The present study had a number of strengths, including analysis of most of the relevant clinical and PSG characteristics of POSA patients, and the performance of full-night PSG in the laboratory. Moreover, the CC and APOC criteria were both applied, with adjustment for potential confounding factors to avoid false-negat...
sense_dimmed_sleep/s12931022021413_245_0.txt
si-POSA:
sense_dimmed_sleep/s41598023340024_254_0.txt
### Share this article
sense_dimmed_sleep/s12931022021413_452_0.txt
Anyone you share the following link with will be able to read this content:
sense_dimmed_sleep/s12931022021413_255_0.txt
WSP:
sense_dimmed_sleep/s41598023340024_66_0.txt
### Sleep studies
sense_dimmed_sleep/s12931022021413_91_4.txt
POSA increased with increasing AHI. The prevalence of POSA decreased significantly with increasing AHI (Fig. [ 4 ](/articles/10.1186/s12931-022-02141-3#Fig4) a, c) with similar trends according to both the CC and APOC criteria. The prevalence of si-POSA was higher in mild OSA than sp-POSA (Fig. [ 4 ](/articles/10.1186/...
sense_dimmed_sleep/s41598023340024_274_0.txt
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sense_dimmed_sleep/s41598023340024_263_0.txt
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sense_dimmed_sleep/s12931022021413_187_0.txt
The datasets used and analyzed in this study are available from Hongliang Yi, the corresponding author, on reasonable request.
sense_dimmed_sleep/therelationshipbetwe_120_0.txt
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sense_dimmed_sleep/s12931022021413_443_16.txt
uMzEtLjU4LS40Ny0xLjA2LS40Ny0uNDEgMC0uNzcuMTUtMS4wNy40NS0uMzEuMjktLjUuNzMtLjU4IDEuM3ptMi41LjYyYzAtLjU3LjA5LTEuMDguMjgtMS41My4xOC0uNDQuNDMtLjgyLjc1LTEuMTNzL
sense_dimmed_sleep/s12931022021413_328_0.txt
36. Guan J, Yi H, Zou J, Meng L, Tang X, Zhu H, et al. Distinct severity stages of obstructive sleep apnoea are correlated with unique dyslipidaemia: large-scale observational study. Thorax. 2016;71(4):347–55. [ https://doi.org/10.1136/thoraxjnl-2015-207403 ](https://doi.org/10.1136/thoraxjnl-2015-207403).