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in one patient the stone was removed by another attempt with the dormia procedure and two patients underwent operation .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 72, 81 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 109, 118 ] }
finally , factors affecting the progression of iga nephritis , the commonest form of gn occurring in singapore are examined .
nichd_parent_of
{ "id": "C0027697", "name": "nephritis", "pos": [ 51, 60 ] }
{ "id": "C0017658", "name": "gn", "pos": [ 85, 87 ] }
this review presents an approach to the pathophysiology , diagnosis , and therapy of rta by defining three major subgroups : proximal rta , distal rta presenting with normal or decreased serum potassium ( hypokalemic distal rta ) , and distal rta presenting with increased serum potassium ( hyperkalemic distal rta ) .
nichd_parent_of
{ "id": "C0001126", "name": "rta", "pos": [ 85, 88 ] }
{ "id": "C0268435", "name": "proximal rta", "pos": [ 125, 137 ] }
human tnf was detected fairly recently and at present the anti-tumor activity of human recombinant tnf is being examined against various malignant tumors of human origin .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 63, 68 ] }
{ "id": "C0006826", "name": "malignant tumors", "pos": [ 137, 153 ] }
microbiologically , most cases of native valve endocarditis ( 67 % ) were due to sensitive organisms ( streptococci ) whilst the more virulent organisms ( staphylococci , gram-negative bacteria and fungi ) were observed in prosthetic valve endocarditis ( 64 % of cases ) .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 91, 100 ] }
{ "id": "C0016832", "name": "fungi", "pos": [ 198, 203 ] }
twenty cases of adult-type respiratory distress syndrome ( ards ) observed in children aged less than 15 years ( excluding neonates ) are reported ;
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 78, 86 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 123, 131 ] }
they are able to enhance virus-induced tumor development and/or to induce acquired immune deficiency syndromes ( aids ) which are characterized by malignant tumors and opportunistic infections .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 39, 44 ] }
{ "id": "C0006826", "name": "malignant tumors", "pos": [ 147, 163 ] }
because of the deceptively benign appearance of many angiosarcomas , these lethal tumors are often misdiagnosed as benign hemangiomas .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 82, 88 ] }
{ "id": "C0018916", "name": "benign hemangiomas", "pos": [ 115, 133 ] }
injuries included splenic hematoma , hepatic injury , duodenal hematoma , traumatic pancreatitis , retroperitoneal hematoma , renal pelvis laceration , and perinephric hematoma .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 0, 8 ] }
{ "id": "C0043246", "name": "laceration", "pos": [ 139, 149 ] }
the correlation is shown between the tumour anaplasia signs including an interphase nuclei morphometry , x-chromatin content and mitotic index on the one hand and the degree of clinical malignancy confirmed by the results of 5-years survival on the other .
nichd_parent_of
{ "id": "C0027651", "name": "tumour", "pos": [ 37, 43 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 186, 196 ] }
although dfa cytology shares the low sensitivity of other laboratory methods of diagnosing trachoma , we believe its logistical advantages make it the laboratory test of choice .
nichd_parent_of
{ "id": "C0430022", "name": "methods", "pos": [ 69, 76 ] }
{ "id": "C0022885", "name": "laboratory test", "pos": [ 151, 166 ] }
interstitial lung disease is a common feature of scleroderma ( systemic sclerosis ) , and it may be a major determinant of morbidity and mortality .
nichd_parent_of
{ "id": "C0011644", "name": "scleroderma", "pos": [ 49, 60 ] }
{ "id": "C0036421", "name": "systemic", "pos": [ 63, 71 ] }
frequency of colon cancer ( also other non-infective bowel diseases , e.g . appendicitis ) is very low in rural and urban blacks , is low in indians and coloureds , yet much higher in whites .
nichd_parent_of
{ "id": "C0009450", "name": "infective", "pos": [ 43, 52 ] }
{ "id": "C0003615", "name": "appendicitis", "pos": [ 76, 88 ] }
carnitine transport by guinea-pig enterocytes demonstrate characteristics of a carrier-mediated process since it was inhibited by d-carnitine and trimethylaminobutyrate , as well as being temperature and concentration dependent .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 58, 73 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 188, 199 ] }
on a clinical and morphologic level , homozygous he imitates two other forms of congenital hemolytic anemia associated with a spectrin self-association defect : he with pycnocytosis in infancy and hereditary pyropoikilocytosis .
nichd_parent_of
{ "id": "C0013902", "name": "he", "pos": [ 49, 51 ] }
{ "id": "C0520739", "name": "hereditary pyropoikilocytosis", "pos": [ 197, 226 ] }
leukemic cells from 89 ( 24 % ) of 369 children with newly diagnosed acute lymphoblastic leukemia ( all ) were found to have a pre-b immunophenotype .
nichd_parent_of
{ "id": "C0023449", "name": "acute", "pos": [ 69, 74 ] }
{ "id": "C1292769", "name": "pre-b", "pos": [ 127, 132 ] }
this study supports the suggestion that the vascular disorder in scleroderma differs from that seen in other rheumatic diseases which are associated with raynaud 's phenomenon .
nichd_parent_of
{ "id": "C0042373", "name": "vascular disorder", "pos": [ 44, 61 ] }
{ "id": "C0034735", "name": "raynaud 's", "pos": [ 154, 164 ] }
occasionally , skin involvement in cancer patients is biologically unrelated to the tumor but is instead part of a well-defined inherited syndrome featuring an increased incidence of internal cancer .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 84, 89 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 192, 198 ] }
in tumors greater than 2 cm , increasing size did not show a corresponding increase in pathologic node metastasis or significantly worsening outcomes except for a few very large cancers invading adjacent structures .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 3, 9 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 178, 185 ] }
we performed a cytogenetic analysis of eosinophilic colonies grown from bone marrow culture of a patient with acute myelogenous leukemia ( fab-m2 ) associated with t ( 8 ; 21 ) .
nichd_parent_of
{ "id": "C0023467", "name": "acute myelogenous leukemia", "pos": [ 110, 136 ] }
{ "id": "C1879321", "name": "fab-m2", "pos": [ 139, 145 ] }
in four of five woodchuck primary hccs , whv dna integration was demonstrated in addition to various amounts of extrachromosomal replicative intermediate whv dna .
nichd_parent_of
{ "id": "C0019158", "name": "whv", "pos": [ 41, 44 ] }
{ "id": "C0042721", "name": "whv", "pos": [ 154, 157 ] }
a 30-min incubation with tpa led to marked growth arrest in hl60 cells and in cells from most patients with acute myelogenous leukemia and acute myelomonocytic leukemia , whereas cells from most patients with acute promyelocytic leukemia and acute undifferentiated leukemia demonstrated a lesser degree of growth arrest ...
nichd_parent_of
{ "id": "C0023467", "name": "acute myelogenous", "pos": [ 108, 125 ] }
{ "id": "C0023479", "name": "acute myelomonocytic leukemia", "pos": [ 139, 168 ] }
surprisingly , the mutations have no detectable effect on the following characteristics : growth rates at various temperatures , in fermentative or in respiratory metabolism , in rich or in minimal media ;
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 72, 87 ] }
{ "id": "C0039476", "name": "temperatures", "pos": [ 114, 126 ] }
patients were evaluated within 24 hr of admission by history , physical examination , cardiac enzyme levels , right heart catheterization , and radionuclide angiography ;
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 14, 23 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 63, 83 ] }
the abnormal intermediate-affinity t4 binding to albumin which is characteristic of familial dysalbuminaemic hyperthyroxinaemia ( fdh ) is dependent on buffer , temperature , and ionic composition .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 66, 80 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 161, 172 ] }
in addition to the various cerebral anomalies such as gyral or lobar abnormalities , hippocampal dysplasia , abnormal lateral geniculate body , agenesis or hypoplasia of the corpus callosum , absent or hypoplastic olfactory nerves , small optic tracts , and dysplasia of the inferior olivary nucleus , hypoplasia of the ...
nichd_parent_of
{ "id": "C0000768", "name": "abnormalities", "pos": [ 69, 82 ] }
{ "id": "C0026010", "name": "small optic", "pos": [ 233, 244 ] }
fresh examination of tissue is critical after any abortion in order to rule out incomplete or missed abortion and to detect ectopic or molar pregnancy .
nichd_parent_of
{ "id": "C0156543", "name": "abortion", "pos": [ 50, 58 ] }
{ "id": "C0000814", "name": "missed abortion", "pos": [ 94, 109 ] }
a surgical dilation and evacuation of the uterus may be undertaken between 12 and 20 weeks ' gestation for women with prior uterine surgery , contraindication to prostaglandin use , no future childbearing being desired , and a fetus having a known lethal chromosomal abnormality ( e.g . trisomy 13 or 18 ) .
nichd_parent_of
{ "id": "C0008625", "name": "chromosomal abnormality", "pos": [ 255, 278 ] }
{ "id": "C0152095", "name": "trisomy 13", "pos": [ 287, 297 ] }
exceptions may be women whose abortion is complicated by pre-existing c. trachomatis and others who experience post-abortion infection leading to pid .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 125, 134 ] }
{ "id": "C0242172", "name": "pid", "pos": [ 146, 149 ] }
the disorder shares features with erythema multiforme and is thought to be an expression of the syndrome .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 4, 12 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 96, 104 ] }
of ten who died in this group , three were diagnosed as having cerebral death shortly after admission ;
nichd_parent_of
{ "id": "C0011065", "name": "died", "pos": [ 11, 15 ] }
{ "id": "C0006110", "name": "cerebral death", "pos": [ 63, 77 ] }
it also demonstrates that surgical techniques using the trans-sternal approach do not guarantee complete removal of the thymus .
nichd_parent_of
{ "id": "C0543467", "name": "surgical techniques", "pos": [ 26, 45 ] }
{ "id": "C0015250", "name": "complete removal", "pos": [ 96, 112 ] }
it is advantagenous to use this fistula construction in `` '' problematic '' '' patients when there are no other possibilities for an arteriovenous shunt .
nichd_parent_of
{ "id": "C0016169", "name": "fistula", "pos": [ 32, 39 ] }
{ "id": "C0003855", "name": "arteriovenous shu", "pos": [ 134, 151 ] }
clinical trials indicate alfentanil can be used effectively as an analgesic , an analgesic supplement to anesthesia , an anesthetic induction agent , and as the major component of a general anesthetic .
nichd_parent_of
{ "id": "C0002903", "name": "anesthesia", "pos": [ 105, 115 ] }
{ "id": "C0002915", "name": "general anesthetic", "pos": [ 182, 200 ] }
a group of 98 patients ( group a ) , chosen at random , was operated on under such combined anesthesia and compared to a similar group of 98 patients ( group b ) , equally chosen at random , operated on under either spinal or general anesthesia with no epidural morphine added .
nichd_parent_of
{ "id": "C0002903", "name": "anesthesia", "pos": [ 92, 102 ] }
{ "id": "C0002915", "name": "general", "pos": [ 226, 233 ] }
[ a study on the changes with age in thyroid function during infancy , childhood and adolescence ] .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 71, 80 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 85, 96 ] }
it seems that motor development of healthy preterm and fullterm infants differs primarily as a function of gestational age at birth , which supports maturational theory and the practice of making age adjustments when evaluating motor development of preterm infants .
nichd_parent_of
{ "id": "C0678723", "name": "maturational", "pos": [ 149, 161 ] }
{ "id": "C0870919", "name": "motor development", "pos": [ 228, 245 ] }
of the 80 patients admitted to the hospitals in verona , 79 % were suffering from pre-existing cardiopathy ( 40 % rheumatic heart disease , 25 % valvular prosthesis , 7.5 % congenital heart disease , 5 % prolapsing mitral valve , 1.2 % obstructive hypertrophic cardiomyopathy ) ;
nichd_parent_of
{ "id": "C0018799", "name": "cardiopathy", "pos": [ 95, 106 ] }
{ "id": "C0035439", "name": "rheumatic heart disease", "pos": [ 114, 137 ] }
the number and to some extent the nature of tests , procedures , and initial treatments ordered varied by specialty and within specialty subgroups ( i.e. , housestaff , full-time academic , and volunteer clinical faculty members ) .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 52, 62 ] }
{ "id": "C0087111", "name": "treatments", "pos": [ 77, 87 ] }
in the last 2 years we have treated 8 patients with tma ( 5 with thrombotic thrombocytopenic purpura ; 3 with hemolytic uremic syndrome ) with defibrotide , a new antithrombotic agent extracted from mammalian lungs .
nichd_parent_of
{ "id": "C2717961", "name": "tma", "pos": [ 52, 55 ] }
{ "id": "C0034155", "name": "thrombotic thrombocytopenic purpura", "pos": [ 65, 100 ] }
four member institutions of the southeastern cancer study group ( secsg ) investigated 27 cases of malignant lymphoma proved to be of t-cell origin by a frozen section immunoperoxidase technique .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 45, 51 ] }
{ "id": "C0024299", "name": "malignant lymphoma", "pos": [ 99, 117 ] }
the eventual isolation of disease loci should lead to a better understanding of the molecular basis of inherited disease .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 26, 33 ] }
{ "id": "C0019247", "name": "inherited", "pos": [ 103, 112 ] }
since a model of staphylococcal skin infection adequately reflecting human disease was unavailable , a self-limiting animal infection model specific for virulent staphylococcus species was developed .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 75, 82 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 124, 133 ] }
in further analysis of the neutrophil response to surface and fluid-phase stimulation , release of neutrophil cytotoxic mediators was found to vary according to the type of stimulus provided : cell exposure to either larvae opsonized by antibody plus complement or to chemotactic factors provoked low-to-moderate cell re...
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 62, 67 ] }
{ "id": "C0003241", "name": "antibody", "pos": [ 237, 245 ] }
the immunoblotting pattern of sera from healthy controls was even weaker but was directed against the same polypeptides as in the patients suggesting a quantitative rather than qualitative difference between healthy and diseased subjects .
nichd_parent_of
{ "id": "C0205556", "name": "qualitative", "pos": [ 177, 188 ] }
{ "id": "C0018684", "name": "healthy", "pos": [ 208, 215 ] }
the results indicate that the clinical disease , virologic and immunologic courses were similar to that of the human infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 39, 46 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 117, 126 ] }
metabolites of fluorouracil may provide enhanced control of cell proliferation and contractility in the management of ocular disorders such as proliferative vitreoretinopathy and glaucoma .
nichd_parent_of
{ "id": "C0015397", "name": "the", "pos": [ 100, 103 ] }
{ "id": "C0017601", "name": "glaucoma", "pos": [ 179, 187 ] }
meningiomas could be distinguished from tumors within the brain parenchyma because they usually were broad-based , peripherally located masses that were enhanced homogeneously with contrast material .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 40, 46 ] }
{ "id": "C0577559", "name": "masses", "pos": [ 136, 142 ] }
these findings made it easy to differentiate rhinosporidiosis from the more common nasal mycoses such as cryptococcosis .
nichd_parent_of
{ "id": "C0026946", "name": "mycoses", "pos": [ 89, 96 ] }
{ "id": "C0010414", "name": "cryptococcosis", "pos": [ 105, 119 ] }
the 4-quinolones were regularly active ( mic90 less than 4 mg/l ) against the following bacteria : staphylococcus aureus , s. epidermidis , s. saprophyticus , different enterobacteriaceae , haemophilus influenzae , campylobacter jejuni , pseudomonas aeruginosa , agrobacter spp. , aeromonas spp. , plesiomonas spp. , nei...
nichd_parent_of
{ "id": "C0004611", "name": "bacteria", "pos": [ 88, 96 ] }
{ "id": "C0027575", "name": "neisseria meningitidis", "pos": [ 317, 339 ] }
we conclude that the nonuniform forcing produced by immersion provides unique insights into the mechanical characteristics of the abdomen and rib cage , that immersion-induced length changes differ among the inspiratory muscles according to their locations and the depth of immersion , and that such length changes may h...
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 107, 122 ] }
{ "id": "C1444754", "name": "length", "pos": [ 300, 306 ] }
epidemiologic data on the prevalence rates for various dsm-iii categories of anxiety disorders , including panic disorder , agoraphobia , and generalized anxiety disorder , are now available from several community studies of adults .
nichd_parent_of
{ "id": "C0003469", "name": "anxiety disorders", "pos": [ 77, 94 ] }
{ "id": "C0001818", "name": "agoraphobia", "pos": [ 124, 135 ] }
epidemiologic data on the prevalence rates for various dsm-iii categories of anxiety disorders , including panic disorder , agoraphobia , and generalized anxiety disorder , are now available from several community studies of adults .
nichd_parent_of
{ "id": "C0003469", "name": "anxiety disorders", "pos": [ 77, 94 ] }
{ "id": "C0270549", "name": "generalized", "pos": [ 142, 153 ] }
isoflurane anesthesia was also studied in a second group of rats to see if a different general anesthetic agent would cause the same effects that halothane causes .
nichd_parent_of
{ "id": "C0002903", "name": "anesthesia", "pos": [ 11, 21 ] }
{ "id": "C0002915", "name": "general anesthetic", "pos": [ 87, 105 ] }
these results indicate that gh responses to ghrh testing are relatively constant throughout puberty and young adulthood , that iss children respond normally to ghrh , and that the ghrh test is not a reliable discriminator between individual normal and ghd children .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 230, 240 ] }
{ "id": "C0008059", "name": "children", "pos": [ 256, 264 ] }
cerebrospinal fluids examined included those from untreated ( group ia ) and treated ( group ib ) mycobacterium tuberculosis meningitis , nonseptic central nervous conditions ( group ii ) such as epilepsy , viral meningitis , and tetany , and nonmycobacterial septic meningitis ( group iii ) .
nichd_parent_of
{ "id": "C0025289", "name": "meningitis", "pos": [ 125, 135 ] }
{ "id": "C0025297", "name": "viral meningitis", "pos": [ 207, 223 ] }
sitosterolemia and xanthomatosis together are a disease characterized by premature cardiovascular disease , and by elevated plasma concentrations of total sterols and of plant sterols , especially sitosterol which is hyperabsorbed .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 48, 55 ] }
{ "id": "C0007222", "name": "cardiovascular disease", "pos": [ 83, 105 ] }
no significant difference existed between patients with and without reinducible arrhythmias with respect to severity of coronary artery disease , degree of left ventricular dysfunction , occurrence of ventricular fibrillation in the acute phase of infarction and ventricular arrhythmias detected by 24 hour ambulatory el...
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 80, 91 ] }
{ "id": "C0085612", "name": "ventricular", "pos": [ 263, 274 ] }
relation between ventricular arrhythmia and sudden cardiac death in patients with acute myocardial infarction : the predictors of ventricular fibrillation .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmia", "pos": [ 17, 39 ] }
{ "id": "C0042510", "name": "ventricular fibrillation", "pos": [ 130, 154 ] }
quinidine therapy is one of the most common causes of the acquired long qt syndrome and the morphologically distinctive tachyarrhythmia torsade de pointes .
nichd_parent_of
{ "id": "C0080203", "name": "tachyarrhythmia", "pos": [ 120, 135 ] }
{ "id": "C0040479", "name": "torsade de pointes", "pos": [ 136, 154 ] }
this paper discusses the incidence , histology , clinical findings , diagnosis , and treatment of this malignant lesion .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 49, 66 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 69, 78 ] }
we have developed procedures whereby the progression of errors in various methods of morphometric data extrapolation may be evaluated .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 18, 28 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 124, 133 ] }
incubation of this organism with subinhibitory doses of clindamycin induced morphological changes in the bacteria , including elongation and loss of cp , detected by ferritin-labeled antibody to capsule .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 19, 27 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 105, 113 ] }
outcomes of pregnancy for which no association with blood lead was detected were spontaneous abortion , low birthweight ( for births at term ) , intrauterine growth retardation , premature rupture of the membranes , and congenital anomalies .
nichd_parent_of
{ "id": "C0032972", "name": "outcomes of pregnancy", "pos": [ 0, 21 ] }
{ "id": "C0233324", "name": "births", "pos": [ 126, 132 ] }
coagulopathy in the form of disseminated intravascular coagulation or massive pulmonary hemorrhage are potentially lethal complications .
nichd_parent_of
{ "id": "C0005779", "name": "coagulopathy", "pos": [ 0, 12 ] }
{ "id": "C0012739", "name": "disseminated intravascular coagulation", "pos": [ 28, 66 ] }
regional amino acid concentrations were measured in rat brain fixed by microwave irradiation at three levels of elevated atmospheric pressure corresponding to different phases of the high-pressure neurological syndrome [ 20 atmospheres absolute ( ata ) , no clinical signs ; 60 ata , tremor ; 85 ata , severe tremor and ...
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 258, 272 ] }
{ "id": "C0040822", "name": "tremor", "pos": [ 309, 315 ] }
regional amino acid concentrations were measured in rat brain fixed by microwave irradiation at three levels of elevated atmospheric pressure corresponding to different phases of the high-pressure neurological syndrome [ 20 atmospheres absolute ( ata ) , no clinical signs ; 60 ata , tremor ; 85 ata , severe tremor and ...
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 258, 272 ] }
{ "id": "C0027066", "name": "myoclonic jerks", "pos": [ 320, 335 ] }
continuous electrocardiographic monitoring was useful in detecting transient arrhythmias and episodes of bradycardia in apneic infants .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 77, 88 ] }
{ "id": "C0428977", "name": "bradycardia", "pos": [ 105, 116 ] }
infants with ivh appeared to be at higher risk for neonatal apnea than their non-ivh peers .
nichd_parent_of
{ "id": "C0240059", "name": "ivh", "pos": [ 13, 16 ] }
{ "id": "C0270191", "name": "neonatal", "pos": [ 51, 59 ] }
the rate of sids in siblings of infants who died of sids did not differ significantly from the sids rate among control infants matched for maternal age and birth order .
nichd_parent_of
{ "id": "C0011065", "name": "died", "pos": [ 44, 48 ] }
{ "id": "C0038644", "name": "sids", "pos": [ 95, 99 ] }
growth ( weight , length , head circumference , and skinfold thickness ) , retention of major nutrients ( nitrogen , sodium , potassium , chloride , calcium , and phosphorus ) , and chemical indices of protein adequacy ( plasma albumin and transthyretin concentrations ) and excess ( blood urea nitrogen concentration an...
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 18, 24 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 27, 45 ] }
weight gain and rate of increase in length and head circumference were less in group 1 than in groups 2 and 3 .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 36, 42 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 47, 65 ] }
the procedure include re-union of the tubal cartilage and anastomosis of the surgically divided external carotid artery and posterior facial vein .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0543467", "name": "surgically", "pos": [ 77, 87 ] }
the principal objective of management of childhood asthma in general practice should not be the prevention of deaths , which now occur at rates of between two and 25 per million people , but to help children with minor asthma to conserve respiratory function and become normal adults .
nichd_parent_of
{ "id": "C0027361", "name": "people", "pos": [ 178, 184 ] }
{ "id": "C0008059", "name": "children", "pos": [ 199, 207 ] }
a family is presented in which at least five members in three generations suffered a characteristic syndrome of generalised lipoatrophy , sparing the head and neck , and muscle hypertrophy variably associated with high plasma insulin and lipid levels and insulin resistant diabetes .
nichd_parent_of
{ "id": "C0039082", "name": "syndrome", "pos": [ 100, 108 ] }
{ "id": "C0221032", "name": "generalised lipoatrophy", "pos": [ 112, 135 ] }
one model was characterized by a well-defined dense transmural scar ( discrete myocardial infarction ) , while the other demonstrated a pattern of nontransmural diffuse patchy fibrosis in the infarct area ( diffuse myocardial infarction ) .
nichd_parent_of
{ "id": "C0021308", "name": "infarct", "pos": [ 90, 97 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 215, 236 ] }
we evaluated 59 consecutive patients for obstructive voiding symptoms with physical examination , excretory urography , urethrocystoscopy , post-voiding residual volumes , uroflowmetry and transabdominal ultrasound of the prostate .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 3, 12 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 75, 95 ] }
cod which survived dual infections had lower k-factor and blood values than controls or fish harboring single , parasitic infections .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 24, 34 ] }
{ "id": "C0747256", "name": "parasitic infections", "pos": [ 112, 132 ] }
i have reviewed clinical trials that provide data relative to the comparative rates , means , or odds ratio of jaundiced normal breast-fed newborns vs jaundiced normal formula-fed newborns .
nichd_parent_of
{ "id": "C0022346", "name": "jaundiced", "pos": [ 111, 120 ] }
{ "id": "C0022353", "name": "jaundiced", "pos": [ 151, 160 ] }
the adm caused moderate to remarkable alterations in ecg at a dose of 3.13 mg/kg or 6.25 mg/kg , including arrhythmia , bradycardia , a-v block , st segment changes and t wave flattening .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmia", "pos": [ 107, 117 ] }
{ "id": "C0428977", "name": "bradycardia", "pos": [ 120, 131 ] }
compared with primary malignant bone tumors , carcinomas metastatic to the bone were more likely to show hematologic disorders such as anemia and leukocytosis .
nichd_parent_of
{ "id": "C0018939", "name": "hematologic disorders", "pos": [ 105, 126 ] }
{ "id": "C0002871", "name": "anemia", "pos": [ 135, 141 ] }
the statewide population-based new mexico tumor registry identified 473 malignant tumors among children of ages 0-14 years , during the period 1970-82 .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 42, 47 ] }
{ "id": "C0006826", "name": "malignant tumors", "pos": [ 72, 88 ] }
known risk factors ( occupational exposure to chemicals and cigarette smoking ) and suspected risk factors ( coffee consumption and artificial sweetener use ) had no effect on disease-free interval and are not related to tumor multiplicity .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 176, 183 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 221, 226 ] }
the injuries consisted of severe contusion and perforation damage to the cornea , traumatic cataract , vitreous hemorrhage , and multiple small intraocular foreign bodies frequently impacting on or penetrating the retina .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 4, 12 ] }
{ "id": "C0009938", "name": "contusion", "pos": [ 33, 42 ] }
the patient 's flecainide plasma level did not decrease sufficiently during the procedure , showing clearly that flecainide levels can not be lowered fast enough by hemoperfusion to treat a flecainide intoxication .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 80, 89 ] }
{ "id": "C0087111", "name": "treat", "pos": [ 182, 187 ] }
thirty adult mongrel dogs underwent either the cryosurgical procedure ( n = 20 ) or a sham operation ( n = 10 ) .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 60, 69 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 91, 100 ] }
on the other hand , prophylactic or therapeutic modalities that deter colonization or invasion by pathogenetic organisms or that alter the ability of pathogens to evoke adverse host responses may be more likely to impact on the incidence and morbidity of gram-negative bacillary infections .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 111, 120 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 150, 159 ] }
the human interleukin-1 ( il-1 ) family plays an important role in the pathogenesis of many disease processes and also functions as mediator of the host 's response to various infectious , inflammatory and immunologic challenges .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 92, 99 ] }
{ "id": "C0009450", "name": "infectious", "pos": [ 176, 186 ] }
the organism was isolated from sputum of a 56-year-old patient with lung disease and is considered to be a lung pathogen .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 4, 12 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 112, 120 ] }
present study was undertaken to investigate accumulation of radiolabeled antibody to cea in cea-producing tumor and possibility of radioimmunodetection of cancer with antibody .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 106, 111 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 155, 161 ] }
this procedure , sphinctero-myectomy and-plasty may be an operation of choice for chronic constipation with megarectum .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 5, 14 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 58, 67 ] }
from these results , it is recommended that lobectomy is the least requirement in treating clinically benign nodule and that , when paraffin section reveals the tumor is intrathyroidal cancer , no further surgery is justified unless there are other foci of cancer in the resected lobe .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 161, 166 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 257, 263 ] }
as normal electrophysiologic studies occur in carpal tunnel syndrome ( up to 8 % ) and median to ulnar communications are common ( 15 % -31 % ) , this observed finding is of practical clinical importance in the diagnosis of mild carpal tunnel syndrome despite otherwise normal electrophysiologic studies .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 160, 167 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 211, 220 ] }
on the basis of these results , we conclude that children should be screened in the neonatal period for sickle cell hemoglobinopathy and that those with sickle cell anemia should receive prophylactic therapy with oral penicillin by four months of age to decrease the morbidity and mortality associated with pneumococcal ...
nichd_parent_of
{ "id": "C0019045", "name": "hemoglobinopathy", "pos": [ 116, 132 ] }
{ "id": "C0002895", "name": "sickle cell anemia", "pos": [ 153, 171 ] }
her injuries may range from bruises to fractures , and the explanation of these injuries is usually inappropriate .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 4, 12 ] }
{ "id": "C0009938", "name": "bruises", "pos": [ 28, 35 ] }
her injuries may range from bruises to fractures , and the explanation of these injuries is usually inappropriate .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 4, 12 ] }
{ "id": "C0016658", "name": "fractures", "pos": [ 39, 48 ] }
the immunological identification of subgroups of acute lymphocytic leukemia ( c-all , t-all and b-all ) bears significant meaning for differential therapy .
nichd_parent_of
{ "id": "C0023449", "name": "acute lymphocytic leukemia", "pos": [ 49, 75 ] }
{ "id": "C1292769", "name": "c-all", "pos": [ 78, 83 ] }
[ risk groups in acute , non-lymphatic leukemia in childhood . analysis of the results of the cooperative therapeutic studies aml-bfm 78 and 83 ] .
nichd_parent_of
{ "id": "C0023467", "name": "acute", "pos": [ 17, 22 ] }
{ "id": "C0220621", "name": "childhood", "pos": [ 51, 60 ] }
the clinical implications of these findings are discussed in relation to the diagnosis of decompensated heterophoria and the prescribing of prismatic corrections .
nichd_parent_of
{ "id": "C0037088", "name": "clinical", "pos": [ 4, 12 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 77, 86 ] }
treatment of children with congenitally dislocated hips requires that an infant be placed into a plaster spica cast for a duration of 3 to 12 months .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 13, 21 ] }
{ "id": "C0021270", "name": "infant", "pos": [ 73, 79 ] }