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this procedure has a special advantage in developing countries since the cost of the operation in reduced by approximately 50 per cent .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 5, 14 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 85, 94 ] }
while we consider the system 's performance characteristics acceptable , the length of time required for each urine lead determination ( approximately 40 minutes ) is a notable limitation to the routine clinical adoption of the instrument in its current configuration .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 44, 59 ] }
{ "id": "C1444754", "name": "length", "pos": [ 77, 83 ] }
our definition , based on 14 years of practical experience , is as follows : in clinical pharmacology , a procedure is adequate if it can be used in normal subjects in a non-invasive way and if it generates relevant information concerning pharmacotherapy in patients .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 106, 115 ] }
{ "id": "C0013216", "name": "pharmacotherapy", "pos": [ 239, 254 ] }
the results of the clinical applications vary according to the method of application and to the type of cancer involved : treatment of inoperable malignancies of the salivary gland is very encouraging : the therapeutic gain is rather small for bladder and rectal cancers , soft tissue sarcomas and advanced carcinomas of...
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 104, 110 ] }
{ "id": "C1261473", "name": "soft tissue sarcomas", "pos": [ 273, 293 ] }
the results of the clinical applications vary according to the method of application and to the type of cancer involved : treatment of inoperable malignancies of the salivary gland is very encouraging : the therapeutic gain is rather small for bladder and rectal cancers , soft tissue sarcomas and advanced carcinomas of...
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 104, 110 ] }
{ "id": "C0302592", "name": "carcinomas of the cervix", "pos": [ 307, 331 ] }
the clinical and histologic features of a keratitis are described and related to fungal keratitis in general .
nichd_parent_of
{ "id": "C0022568", "name": "keratitis", "pos": [ 42, 51 ] }
{ "id": "C1262117", "name": "fungal keratitis", "pos": [ 81, 97 ] }
we believe the clinical circumstances likely to lead to b cereus infection , as well as the manifestations of the disease itself , are sufficiently distinctive to alert the ophthalmologist to the possibility of this infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 114, 121 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 216, 225 ] }
nevertheless , it includes a broad spectrum of disease , with examples of established intrauterine septicemia , amniotic infection syndrome , intrapartum infection , and postnatal infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 47, 54 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 131, 139 ] }
nevertheless , it includes a broad spectrum of disease , with examples of established intrauterine septicemia , amniotic infection syndrome , intrapartum infection , and postnatal infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 47, 54 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 180, 189 ] }
[ decompensated cardiac valve disease associated with tight aortic stenosis . surgical cure in one stage ( author 's transl ) ] .
nichd_parent_of
{ "id": "C0018824", "name": "cardiac valve disease", "pos": [ 16, 37 ] }
{ "id": "C0003507", "name": "aortic stenosis", "pos": [ 60, 75 ] }
the authors report on 2 cases of severe cardiac valve disease associated with tight stenosis of the aortic isthmus for which the standard techniques could not be safely applied owing to patients ' poor condition .
nichd_parent_of
{ "id": "C0018824", "name": "cardiac valve disease", "pos": [ 40, 61 ] }
{ "id": "C0003507", "name": "stenosis of", "pos": [ 84, 95 ] }
since head-shaking behavior in rodents has been proposed as a quantitative , behavioral model of central 5-ht activation , the data suggest a causal relationship between enhanced 5-ht activity and sleep suppression .
nichd_parent_of
{ "id": "C0004927", "name": "behavioral", "pos": [ 77, 87 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 197, 202 ] }
both tests have been shown to be of value in the diagnosis of bacterial infections ( such as those caused by h. influenzae , streptococcus pneumoniae , n. meningitidis , e. coli , staphylococcus aureus and group b streptococcus ) and of viral infections ( hrvla and hepatitis b ) ;
nichd_parent_of
{ "id": "C0042769", "name": "viral infections", "pos": [ 237, 253 ] }
{ "id": "C0019163", "name": "hepatitis", "pos": [ 266, 275 ] }
in one procedure ( separate tests ) the time course of the drug action was established by testing each time interval on separate days with a new injection each test day , whereas in the other procedure ( repeated tests ) all intervals were evaluated after a single injection .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 7, 16 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 240, 249 ] }
soft tissue aspects of skeletal trauma are discussed according to two categories : ( 1 ) those injuries in which the significance of the soft tissue in the pathophysiology of the skeletal lesion is indicated by the characteristics of the skeletal injury ( such as extension teardrop fracture , little leaguer 's elbow , ...
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 95, 103 ] }
{ "id": "C0016658", "name": "fractur", "pos": [ 283, 290 ] }
a particularly useful feature of this model is its ability to yield an understanding of the intrinsic limitations of any one modality .
nichd_parent_of
{ "id": "C1521970", "name": "feature", "pos": [ 22, 29 ] }
{ "id": "C0695347", "name": "modality", "pos": [ 125, 133 ] }
gallium-67 concentrates in a variety of soft-tissue and tumor , however the accumulation is not specific for malignant tumor .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 56, 61 ] }
{ "id": "C0006826", "name": "malignant tumor", "pos": [ 109, 124 ] }
within-day variations in the concentrations of glucose , fructose , lactate , urea , insulin , thyroxine , corticosteroids and individual amino acids in maternal and fetal plasma from 12 scottish blackface ewes between 125 and 134 days of pregnancy were examined during a period of six days .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 127, 137 ] }
{ "id": "C0015965", "name": "fetal", "pos": [ 166, 171 ] }
paraffin-embedded sections from human tissues with fungi or organisms classified with fungi were studied by light microscopy ( lm ) , scanning electron microscopy ( sem ) , and the backscatter electron imaging ( bei ) mode of the sem .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 60, 69 ] }
{ "id": "C0016832", "name": "fungi", "pos": [ 86, 91 ] }
two possible modes of the microorganisms to overcome the mutual repellent forces between the invading organism and the urethral surface cover cell are suggested -- reduction of surface charge in microorganisms with high isoelectric point ( s. saprophyticus ) ( utilizing ph-shift towards increased acidity ) , and attach...
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 31, 39 ] }
{ "id": "C0445623", "name": "microorganisms", "pos": [ 195, 209 ] }
sera from patients with recent disease or patients who had a history of p. falciparum infection gave strong binding , while sera of normal individuals had only a low binding activity .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 31, 38 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 86, 95 ] }
in this bird the first clinical symptoms of the disease ( nervous changes ) were observed in 28 days from infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 48, 55 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 106, 115 ] }
the correlations between the results obtained , accompanying the disease ( basedow disease , focal infections ) and the severity of ophthalmopathy were discussed .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 65, 72 ] }
{ "id": "C0015397", "name": "ophthalmopathy", "pos": [ 132, 146 ] }
the development of modern diagnostic technics ( ultrasound and ct ) has facilitated diagnosis of pancreatic pseudocysts .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic technics", "pos": [ 26, 45 ] }
{ "id": "C0041618", "name": "ultrasound", "pos": [ 48, 58 ] }
the most remarkable finding was the fall in both lipase concentration and output ( 60-70 % ) when compared with control values .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 20, 27 ] }
{ "id": "C0085639", "name": "fall", "pos": [ 36, 40 ] }
no child with homocystinuria was detected in the screened population of more than 300 000 newborn infants .
nichd_parent_of
{ "id": "C0008059", "name": "child", "pos": [ 3, 8 ] }
{ "id": "C0021289", "name": "newborn infants", "pos": [ 90, 105 ] }
hamadryas baboons are more dimorphic than anubis in epigamic features , but not in postcanine dentition , nor , contrary to previous reports , in body weight or canine tooth size .
nichd_parent_of
{ "id": "C1521970", "name": "features", "pos": [ 61, 69 ] }
{ "id": "C0005910", "name": "body weight", "pos": [ 146, 157 ] }
careful evaluation of a sexual function disorder requires evaluation of four areas : physical , intrapsychic , interpersonal , and learning .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 8, 18 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 85, 93 ] }
patients with congenital malformations related to wilms ' tumor ( one aniridia , one hemihypertrophy ) were seen only in the group with '' '' massive '' '' rhabdomyogenesis .
nichd_parent_of
{ "id": "C0000768", "name": "congenital malformations", "pos": [ 14, 38 ] }
{ "id": "C0332890", "name": "hemihypertrophy", "pos": [ 85, 100 ] }
the headache occurred more often in young patients and in patients who had a history of repeating headache or migraine .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 4, 12 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 110, 118 ] }
the unusual finding of strongyloides larvae in the potassium hydroxide preparation for fungi and in the gram stain for bacteria from a sputum during hemoptysis fortuitously established the diagnosis of disseminated strongyloidiasis .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 12, 19 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 189, 198 ] }
multiplication curves determined under 3 , 5 , 10 and 19 percent o2 for each virus at total imput of 10,000 pfu per cell sheet showed that the capacity of poliovirus to multiply under the hypoaerobic conditions of 3 and 5 percent o2 was much stronger than that of adenovirus .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 77, 82 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 155, 165 ] }
among 2400 malignant tumors of the gastrointestinal tract , in 12 tumors ( 11 gastric and 1 jejunal ) having the structure of solid cancer , argyrophil cells constituted the basis of the tumor tissue .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 21, 27 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 132, 138 ] }
a possible relationship of this structural feature to the length of linker dna is proposed .
nichd_parent_of
{ "id": "C1521970", "name": "feature", "pos": [ 43, 50 ] }
{ "id": "C1444754", "name": "length", "pos": [ 58, 64 ] }
the histopathology of the experimentally induced hepatitis with mouse hepatitis type 1 is indistinguishable from that produced by the disease in nude mouse colonies due to the natural infection in the united kingdom and also indistinguishable from the histopathology produced by the nude mouse hepatitis virus isolated i...
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 134, 141 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 184, 193 ] }
using a magnitude production procedure involving forearm isometric contractions , it was found that the ability to discriminate muscle tension varied across headache groups , with the no-headache control group ( r = .76 ) being most accurate , followed by the tension group ( r = .68 ) , the mixed tension and migraine g...
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 157, 165 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 355, 363 ] }
anxiety in labor and plasma epinephrine were significantly correlated with the fetal heart rate pattern during phase 2 of active labor .
nichd_parent_of
{ "id": "C0022864", "name": "labor", "pos": [ 11, 16 ] }
{ "id": "C2985356", "name": "phase", "pos": [ 111, 116 ] }
adp , adrenalin and collagen platelet aggregation studies were performed in 54 patients with elevated platelet counts : 38 patients showed primary thrombocythemia and 16 secondary thrombocytosis .
nichd_parent_of
{ "id": "C0836924", "name": "elevated platelet counts", "pos": [ 93, 117 ] }
{ "id": "C0040028", "name": "primary", "pos": [ 139, 146 ] }
the pneumonia took much longer to resolve in the patients with legionnaires ' disease than in all the other patients ( mean interval from onset of symptoms to clearing of the chest roentgenogram : 69 days v. an average of 16 days ) .
nichd_parent_of
{ "id": "C0032285", "name": "pneumonia", "pos": [ 4, 13 ] }
{ "id": "C0023241", "name": "legionnaires", "pos": [ 63, 75 ] }
moreover , armadillo-derived m. leprae readily induced a specific hypersensitivity with the time course dth response associated with protective immunity suggesting that this bacterial preparation may be a candidate for an effective anti-leprosy vaccine .
nichd_parent_of
{ "id": "C0020517", "name": "hypersensitivity", "pos": [ 66, 82 ] }
{ "id": "C0020522", "name": "hypersensitivity", "pos": [ 66, 82 ] }
[ comparative sanitary-toxicologic characteristics of chlorobenzene and dichlorobenzene ( ortho- and para-isomers ) from the viewpoint of the sanitary protection of water reservoirs ] .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 35, 50 ] }
{ "id": "C0030563", "name": "para", "pos": [ 101, 105 ] }
although , theoretically , finding a single bacillus in the sputum should be adequate proof of pulmonary tuberculosis , it is shown that finding of a few bacilli , 3 or less , is probably far too often due to artefacts and should not be the basis for a diagnosis .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 27, 34 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 253, 262 ] }
[ on the subject of primitive benign hemangiomas and the structure of embryonal angiomatosis of the heart ] .
nichd_parent_of
{ "id": "C0018916", "name": "benign hemangiomas", "pos": [ 30, 48 ] }
{ "id": "C0002992", "name": "angiomatosis", "pos": [ 80, 92 ] }
[ occurrence of some orthopedic diseases in childhood and adolescence from the viewpoint of the orthopedic service ] .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 44, 53 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 58, 69 ] }
[ some indices of nitrogen metabolism in experimental infarct and secondary necrosis of the cardiac muscle ] .
nichd_parent_of
{ "id": "C0021308", "name": "infarct", "pos": [ 54, 61 ] }
{ "id": "C0027051", "name": "necrosis", "pos": [ 76, 84 ] }
[ irradiation of the diencephalon and hypophysis in the therapy of hemorrhagic and angiopathic retinal diseases . i. diabetic retinopathy ] .
nichd_parent_of
{ "id": "C0035309", "name": "retinal diseases", "pos": [ 95, 111 ] }
{ "id": "C0011884", "name": "diabetic retinopathy", "pos": [ 117, 137 ] }
[ human cell lines with chromosome aberrations ( trisomy , monosomy and triploid cells ) , karyotype stability and longevity ] .
nichd_parent_of
{ "id": "C0008625", "name": "chromosome aberrations", "pos": [ 24, 46 ] }
{ "id": "C0333693", "name": "triploid", "pos": [ 72, 80 ] }
[ soluretic effect of proscillaridine . study on normal subjects and on cardiopathic patients during heart failure ] .
nichd_parent_of
{ "id": "C0018799", "name": "cardiopathic", "pos": [ 72, 84 ] }
{ "id": "C0018801", "name": "heart failure", "pos": [ 101, 114 ] }
[ special abdominal pain syndromes accompanied by sicca 's syndrome ( sjogren 's syndrome ) , pseudo bartter 's syndrome , chronic cholestatic viral hepatitis ( pseudo primary biliary cirrhosis ) , massive gastric hemorrhage and icterus combined ] .
nichd_parent_of
{ "id": "C0039082", "name": "syndromes", "pos": [ 25, 34 ] }
{ "id": "C0004775", "name": "bartter 's syndrome", "pos": [ 101, 120 ] }
on the regulation of cerebral blood flow in diseases of the brain with special regard to the `` '' luxury perfusion syndrome '' '' of brain tissue , i.e . a syndrome characterized by relative hyperemia or absolute hyperemia of the brain tissue .
nichd_parent_of
{ "id": "C0006111", "name": "diseases of the brain", "pos": [ 44, 65 ] }
{ "id": "C0085584", "name": "syndrom", "pos": [ 116, 123 ] }
[ hepatitis in monkeys after inoculation with adenoviruses from patients with viral hepatitis . i. determination of enzymatic activity during the course of the disease ] .
nichd_parent_of
{ "id": "C0019158", "name": "hepatitis", "pos": [ 2, 11 ] }
{ "id": "C0042721", "name": "viral hepatitis", "pos": [ 78, 93 ] }
[ differential therapy of coronary insufficiency depending on the form of the disease , its stage and the dominating syndrome ] .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 78, 85 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 117, 125 ] }
[ abnormalities of the internal organs in old age . i. abnormalities of the nervous system and of the digestive apparatus ] .
nichd_parent_of
{ "id": "C0000768", "name": "abnormalities", "pos": [ 2, 15 ] }
{ "id": "C0497552", "name": "abnormalities of the", "pos": [ 55, 75 ] }
[ hepatitis in monkeys following inoculation with adenovirus from humans with viral hepatitis . ii . histopathological findings ] .
nichd_parent_of
{ "id": "C0019158", "name": "hepatitis", "pos": [ 2, 11 ] }
{ "id": "C0042721", "name": "viral hepatitis", "pos": [ 78, 93 ] }
finally , the described techniques lend themselves easily to any sizable peripheral aneurysm and are simpler and safer than other surgical modalities such as total extirpation and bypass procedures .
nichd_parent_of
{ "id": "C0543467", "name": "surgical", "pos": [ 130, 138 ] }
{ "id": "C0015250", "name": "total", "pos": [ 158, 163 ] }
the anit-k1 together with the anti-a and anti-b also present in the fluid , is compared with antibodies present in the patient 's serum .
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 68, 73 ] }
{ "id": "C0003241", "name": "antibodies", "pos": [ 93, 103 ] }
in studying autoimmune processes in patients with disordered brain circulation previous diseases should be taken into consideration ( brain trauma , epilepsy , strokes ) .
nichd_parent_of
{ "id": "C0006111", "name": "brain", "pos": [ 61, 66 ] }
{ "id": "C0014544", "name": "epilepsy", "pos": [ 149, 157 ] }
scandinavian psychiatrists acknowledge endogenous psychoses which are neither schizophrenic nor manic-depressive , i.e. , above all the `` '' reactive psychoses '' '' and the `` '' schizophreniform psychoses '' '' , both of which differ from schizophrenia in their features as well as in their good prognoses .
nichd_parent_of
{ "id": "C0004936", "name": "psychoses", "pos": [ 50, 59 ] }
{ "id": "C0005586", "name": "manic-depressive", "pos": [ 96, 112 ] }
in animals in group i , transient major arrhythmias , including complete heart block and ventricular tachycardia , occurred immediately after impact .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 40, 51 ] }
{ "id": "C0151517", "name": "complete heart block", "pos": [ 64, 84 ] }
creatinine per minute excretion rates in individual voidings varied as much as 300-500 percent of the 24-hour value for several children .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 41, 51 ] }
{ "id": "C0008059", "name": "children", "pos": [ 128, 136 ] }
the creatinine height index when calculated from timed individual voidings during a 24-hour period varied for some children from 0.5 to more than 1.5 times published norms .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 55, 65 ] }
{ "id": "C0008059", "name": "children", "pos": [ 115, 123 ] }
it is pointed out that the listeria organism is commonly mistaken for erysipelothrix and diphtheroids and that a battery of tests should be employed before one disregards these microorganisms as `` '' contaminants '' '' .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 36, 44 ] }
{ "id": "C0445623", "name": "microorganisms", "pos": [ 177, 191 ] }
it is important to recognize the multiplicity of diagnoses on individual elementary school children , as well as the differentiation of early organics from late functional primary causes .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 62, 72 ] }
{ "id": "C0008059", "name": "children", "pos": [ 91, 99 ] }
the long-term survival in the ulcerogenic tumor syndrome approximated 50 per cent , with 40 per cent of those having proved malignancy living five years .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 42, 47 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 124, 134 ] }
malignant human neoplasms ( eg , melanoma , basal cell epithelioma , squamous cell carcinoma , lymphoma ) produced striking neovascularization ;
nichd_parent_of
{ "id": "C0006826", "name": "malignant", "pos": [ 0, 9 ] }
{ "id": "C0025202", "name": "melanoma", "pos": [ 33, 41 ] }
malignant human neoplasms ( eg , melanoma , basal cell epithelioma , squamous cell carcinoma , lymphoma ) produced striking neovascularization ;
nichd_parent_of
{ "id": "C0006826", "name": "malignant", "pos": [ 0, 9 ] }
{ "id": "C0024299", "name": "lymphoma", "pos": [ 95, 103 ] }
we conclude that patients harboring occipital avms may , indeed , have visual phenomena and headache that should not be confused with migraine because either a history of generalized seizure or bruits on examination will probably be present .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 92, 100 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 134, 142 ] }
a validatory study of quantitative single plane left ventricular cineangiography is presented , using human left ventricular casts ranging in size from 1.6 to 135 ml .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 22, 34 ] }
{ "id": "C1514721", "name": "ranging", "pos": [ 131, 138 ] }
this organism belongs to group 3 of the genus , and members of this group have not heretofore been shown to be pathogenic for mice even under experimental conditions .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 5, 13 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 111, 121 ] }
the mean lethal dose ( ld50 ) of the organism for 20-25 g mice by the i.p . route is about 1 times 10-8 bacteria/mouse .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 37, 45 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 104, 112 ] }
the incidence of rats developing one or more mammary carcinomas in each treated group was compared to that ovserved in simultaneously treated groups receiving only the carcinogen , steroid , or no treatment whatsoever , with weekly observation of all rats until palpably growing tumors were biopsied and proven carcinoma...
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 279, 285 ] }
{ "id": "C0006826", "name": "carcinomatous", "pos": [ 311, 324 ] }
public health officials appear to have largely ignored the problem of salpingitis in patients attending public vd clinics and have not been notably successful in making the public aware of the nature of the early manifestations of salpingitis , of the need to seek early treatment in order to preserve fertility , and of...
nichd_parent_of
{ "id": "C0036916", "name": "vd", "pos": [ 111, 113 ] }
{ "id": "C0018081", "name": "gonococcal", "pos": [ 369, 379 ] }
investigations of infectious diseases in general , and pelvic inflammatory disease in particular , must increasingly enter the mainstream of research in the future if this disease is to be effectively treated and/or prevented in gynecologic patients .
nichd_parent_of
{ "id": "C0009450", "name": "infectious diseases", "pos": [ 18, 37 ] }
{ "id": "C0242172", "name": "pelvic", "pos": [ 55, 61 ] }
in a 68-year-old female patient glossopharyngeal neuralgia of unknown origin occurred accompained by cardiac arrhythmias ( bradycardia to asystole ) and loss of consciousness .
nichd_parent_of
{ "id": "C0003811", "name": "cardiac arrhythmias", "pos": [ 101, 120 ] }
{ "id": "C0428977", "name": "bradycardia", "pos": [ 123, 134 ] }
cardinal clinical signs are retrosternal pain , marked shock with dyspnoea and tachycardia or rapidly progressive cardiac failure .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 9, 23 ] }
{ "id": "C0013404", "name": "dyspnoea", "pos": [ 66, 74 ] }
these findings suggest a delayed peripheral neuropathy indicative of a trophic deprivation and further illustrate a motor nerve terminal deficit as the initial function alteration in dfp neuropathy .
nichd_parent_of
{ "id": "C0031117", "name": "peripheral", "pos": [ 33, 43 ] }
{ "id": "C0442874", "name": "neuropathy", "pos": [ 187, 197 ] }
the cellular infiltrate of the proximal jejunum has been compared between 20 subjects without gastrointestinal disease , 20 subjects with ulcerative colitis , and 26 subjects with crohn 's disease .
nichd_parent_of
{ "id": "C0017178", "name": "gastrointestinal disease", "pos": [ 94, 118 ] }
{ "id": "C0010346", "name": "crohn 's disease", "pos": [ 180, 196 ] }
the dogs were euthanatized after 10 to 15 days of progressive clinical signs , including muscular weakness , subcutaneous edema , anorexia , depression , dyspnea , and eventual coma .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 62, 76 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 130, 138 ] }
the dogs were euthanatized after 10 to 15 days of progressive clinical signs , including muscular weakness , subcutaneous edema , anorexia , depression , dyspnea , and eventual coma .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 62, 76 ] }
{ "id": "C0013404", "name": "dyspnea", "pos": [ 154, 161 ] }
the main features of the system , such as ion and nucleotide requirements , temperature , dependence , inhibitors sensitivity , and ability to reinitiate , were studied .
nichd_parent_of
{ "id": "C1521970", "name": "features", "pos": [ 9, 17 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 76, 87 ] }
however , evaluation of individual patterns of growth during the follow-up period revealed that children who received small doses of alternate-day treatment ( mean dose of prednisone , 9 mg . q.o.d . ; range , 2.5 to 14 mg. ) had acceleration of growth , whereas children who received larger treatment doses ( mean dose ...
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 24, 34 ] }
{ "id": "C0008059", "name": "children", "pos": [ 263, 271 ] }
in this study an enzymatic colorimetric method was used to assay serum dbh activity in 196 individuals of whom 169 were either the parents or children in 29 families .
nichd_parent_of
{ "id": "C0027361", "name": "individuals", "pos": [ 91, 102 ] }
{ "id": "C0008059", "name": "children", "pos": [ 142, 150 ] }
thus , the described procedure might be employed to evaluate morphine substitution and hence potential physical dependence liability of unknown narcotic-like analgesics .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 21, 30 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 52, 60 ] }
the most frequent findings in the heart with collagen diseases were pericarditis , fibrous scarring of the heart muscle , focal inflammation and vasculitis is similar to periarteritis nodosa or endoarteritis obliterans .
nichd_parent_of
{ "id": "C0042384", "name": "vasculitis", "pos": [ 145, 155 ] }
{ "id": "C0031036", "name": "periarteritis nodosa", "pos": [ 170, 190 ] }
a considerable proportion of patients with extensive infarction in their history were found to suffer from chronic left ventricle incompetence with recurrent attacks of cardiac asthma .
nichd_parent_of
{ "id": "C0021308", "name": "infarction", "pos": [ 53, 63 ] }
{ "id": "C0027051", "name": "attacks", "pos": [ 158, 165 ] }
the earlier a child contracts the infection the more common are uncharacteristic clinical signs like loss of appetite , a raised temperature , parenchymatous icterus and , finally signs of involvement of the central nervous system .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 81, 95 ] }
{ "id": "C0003123", "name": "loss of", "pos": [ 101, 108 ] }
the earlier a child contracts the infection the more common are uncharacteristic clinical signs like loss of appetite , a raised temperature , parenchymatous icterus and , finally signs of involvement of the central nervous system .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 81, 95 ] }
{ "id": "C0015967", "name": "raised temperature", "pos": [ 122, 140 ] }
the differential diagnostical plan requires a series of clinical examinations for the clarification of these pathological conditions , which often comprise more than one disease or one syndrome .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 170, 177 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 185, 193 ] }
[ medico-social aspects of the post-infarct state . clinical , functional , psychological and return-to-work studies of 100 patients with myocardial infarct treated in the coronary unit ] .
nichd_parent_of
{ "id": "C0021308", "name": "infarct", "pos": [ 36, 43 ] }
{ "id": "C0027051", "name": "myocardial infarct", "pos": [ 138, 156 ] }
most neoplasms respond well to conventional cancer therapy , but high-grade malignancies may necessitate reduction or cessation of immunosuppressive therapy as well .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasms", "pos": [ 5, 14 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 44, 50 ] }
using a random selection procedure , 100 patients were evaluated in order to determine the value of prophylactic antibiotics in cesarean section .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 25, 34 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 55, 64 ] }
considerable variation in the evaluation of the individual nurses was observed , which could be partly explained in the categories `` '' administrative work '' '' and `` '' child-oriented activities '' '' by the relative status of the nurses .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 48, 58 ] }
{ "id": "C0008059", "name": "`` '' ch", "pos": [ 167, 175 ] }
in contrast to individuals with either hemolytic anemia without hemoglobinopathy or sickle cell anemia who had beta mrna to alpha mrna ratios of approximately one , a patient with hb s-beta-thalassemia had a ratio of beta mrna to alpha mrna of 0.75 while two subjects with homozygous beta-thalassemia had severe deficien...
nichd_parent_of
{ "id": "C0019045", "name": "hemoglobinopathy", "pos": [ 64, 80 ] }
{ "id": "C0002895", "name": "sickle cell anemia", "pos": [ 84, 102 ] }
cr is shown to be increased in men who have had back pain within 24 hours of testing and no difference was found between men who had had back pain in the past and those who denied ever having had back pain .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 53, 57 ] }
{ "id": "C0004604", "name": "back pain", "pos": [ 196, 205 ] }
the increase in thalassemia syndromes due to population migration over the past 10 years has resulted in the finding of rare types in switzerland : 8 patients with hbs-beta-thalassemia , 2 with hbc-beta-thalassemia , 3 cases of hbh-alpha-thalassemia and 2 cases of hb bart's-alpha-thalassemia are reported .
nichd_parent_of
{ "id": "C0039730", "name": "thalassemia syndromes", "pos": [ 16, 37 ] }
{ "id": "C0005283", "name": "beta-thalassemia", "pos": [ 198, 214 ] }
the increase in thalassemia syndromes due to population migration over the past 10 years has resulted in the finding of rare types in switzerland : 8 patients with hbs-beta-thalassemia , 2 with hbc-beta-thalassemia , 3 cases of hbh-alpha-thalassemia and 2 cases of hb bart's-alpha-thalassemia are reported .
nichd_parent_of
{ "id": "C0039730", "name": "thalassemia syndromes", "pos": [ 16, 37 ] }
{ "id": "C0002312", "name": "alpha-thalassemia", "pos": [ 275, 292 ] }
the bacteriologic , epidemiologic , clinical , and diagnostic findings and management of the scalded skin syndrome ( sss ) in 42 children are reported sss may present in one of three ways : ( 1 ) ritter 's disease in infants , characterized by an acute , generalized bullous dermatitis simulating the appearance of scald...
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 129, 137 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 217, 224 ] }
if another pathologic condition exists , making ultimate hysterectomy likely , it is the procedure of choice for sterilization , avoiding risks , costs , and the inconvenience of another operation .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 89, 98 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 187, 196 ] }
the pulmonary arteriogram proved a safe procedure in the elderly and should be used before therapy is initiated for suspected pulmonary embolism .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 40, 49 ] }
{ "id": "C0087111", "name": "therapy", "pos": [ 91, 98 ] }
the application of this idea to surgical treatment of congenital heart disease has culminated in atriopulmonary bypass for tricuspid atresia , an operation that relieves cyanosis and creates a functionally normal circulation , but which may have late risk due to arrhythmias or valve failure .
nichd_parent_of
{ "id": "C0152021", "name": "of congenital heart disease", "pos": [ 51, 78 ] }
{ "id": "C0243002", "name": "tricuspid atresia", "pos": [ 123, 140 ] }