text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
five stages have been revealed in the ulcer development : tissue necrobiosis and necrosis ( 1-3 days ) , rejection of the necrotic masses ( 3-5 days ) , outgrowth of the connective tissue in the fundus of the ulcer ( 5-13 days ) , reduction of the connective tissue and completion of epithelization ( 13-40 days ) , the ... | nichd_parent_of | {
"id": "C0041582",
"name": "ulcer",
"pos": [
38,
43
]
} | {
"id": "C0236053",
"name": "mucosal",
"pos": [
320,
327
]
} |
the associations regarding other cancers ( i.e. , hodgkin 's disease , non-hodgkin 's lymphoma , multiple myeloma , soft-tissue sarcoma , and cancers of the stomach , brain , and prostate ) are even less clear . | nichd_parent_of | {
"id": "C0006826",
"name": "cancers",
"pos": [
33,
40
]
} | {
"id": "C1261473",
"name": "soft-tissue",
"pos": [
116,
127
]
} |
five sera ( 2 scleroderma , 1 morphea , 12 rheumatoid arthritis , 1 systemic lupus erythematosus ) markedly suppressed 3h-thymidine incorporation into both endothelial cells and fibroblasts ( to greater than 3 sd below the mean of the control group ) . | nichd_parent_of | {
"id": "C0011644",
"name": "scleroderma",
"pos": [
14,
25
]
} | {
"id": "C0036420",
"name": "morphea",
"pos": [
30,
37
]
} |
of the 903 cancers found in t2 , primary liver cancer accounted for 45.4 % , oesophageal cancer 19.8 % , cancer of the respiratory system 11.2 % and bladder cancer 2.7 % . | nichd_parent_of | {
"id": "C0006826",
"name": "cancers",
"pos": [
11,
18
]
} | {
"id": "C0024620",
"name": "primary liver cancer",
"pos": [
33,
53
]
} |
failure of single-drug treatment was associated especially with the presence of additional neuropsychiatric handicaps but also with partial or mixed seizures , symptomatic epilepsy , and a higher number and frequency of tonic-clonic or partial seizures before treatment . | nichd_parent_of | {
"id": "C0036572",
"name": "seizures",
"pos": [
149,
157
]
} | {
"id": "C0751495",
"name": "partial seizures",
"pos": [
236,
252
]
} |
although the presence of a malodorous vaginal discharge and the finding of clue cells on microscopy ( in the absence of trichomonas vaginalis ) are sufficient for the diagnosis , a positive amine test and a vaginal ph of more than 5.0 are useful confirmatory tests . | nichd_parent_of | {
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} | {
"id": "C0011900",
"name": "diagnosis",
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} |
the following review describes the evolution of an effective therapy for shock consisting of steroid in combination with antibiotic and discusses its relevance and application for humans in severe sepsis or septic shock . | nichd_parent_of | {
"id": "C0036974",
"name": "shock",
"pos": [
73,
78
]
} | {
"id": "C0036983",
"name": "septic shock",
"pos": [
207,
219
]
} |
compared to the cleft lip group , the infants with isolated cleft palate showed the following characteristics : short anterior cranial base , short maxilla , reduced posterior maxillary height , reduced dimensions of the mandible -- especially mandibular length -- , narrow naso- and oropharyngeal airway . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
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109
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} | {
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"name": "length",
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solid phase absorption studies as well as competitive binding in fluid phase indicate that the antibodies formed are almost always specific for determinants shared by the endogenous human molecule . | nichd_parent_of | {
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"name": "fluid",
"pos": [
65,
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} | {
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"name": "antibodies",
"pos": [
95,
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]
} |
in order to elucidate immunological aberrations responsible for the increased iga synthesis in such patients , quantitative and qualitative analysis was performed on t alpha cells which have been recently identified as possessing iga specific helper activity on human b cells . | nichd_parent_of | {
"id": "C0205556",
"name": "qualitative",
"pos": [
128,
139
]
} | {
"id": "C0205396",
"name": "identified",
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} |
evidence is presented that chronic delinquents , compared with nonchronic or nondelinquent individuals , tend to have been children who were antisocial in more than 1 setting , who displayed a higher variety of antisocial behaviors , and who showed an early onset of such behaviors . | nichd_parent_of | {
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"name": "individuals",
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} | {
"id": "C0008059",
"name": "children",
"pos": [
123,
131
]
} |
the measuring response is disturbed by the fluctuating concentrations of interfering substances that are present in body fluids . | nichd_parent_of | {
"id": "C0439861",
"name": "substances",
"pos": [
85,
95
]
} | {
"id": "C0005889",
"name": "body fluids",
"pos": [
116,
127
]
} |
at all ages , and for both sexes , the mean weight , length or height , and head circumference values for the two extreme groups differed significantly from the afd group ( p less than 0.001 ) . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
53,
59
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
76,
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]
} |
at each age weight , length or height , and head circumference measures in the sfd and lfd groups were distributed around the appropriate sex afd mean values . | nichd_parent_of | {
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"name": "length",
"pos": [
21,
27
]
} | {
"id": "C0262499",
"name": "head circumference",
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]
} |
trajectories of individual sfd and lfd children illustrate the great diversity of growth patterns within and between groups . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
16,
26
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
39,
47
]
} |
it may be assumed that this is one of those pictures of disease developing in the limiting area of the maturation zone ranging from the lymphoplasmacytoid cell type to the finally differentiated plasma cells and their systemic neoplasia . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
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63
]
} | {
"id": "C0027651",
"name": "neoplasia",
"pos": [
227,
236
]
} |
[ special features of the therapy of hematologic diseases in old age . 1. aging of the immune system and its effect on hemopoiesis . 2. anemia ] . | nichd_parent_of | {
"id": "C0018939",
"name": "hematologic diseases",
"pos": [
37,
57
]
} | {
"id": "C0002871",
"name": "anemia",
"pos": [
136,
142
]
} |
histologically , the tumor cells from the suprasellar mass and the third-ventricular hemorrhage were diagnostic of a pituitary adenoma . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
21,
26
]
} | {
"id": "C0577559",
"name": "mass",
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54,
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]
} |
histologically , the tumor cells from the suprasellar mass and the third-ventricular hemorrhage were diagnostic of a pituitary adenoma . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
21,
26
]
} | {
"id": "C0032000",
"name": "of",
"pos": [
112,
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]
} |
the choice of drugs was based on the finding in our institute that the majority of infections are caused by gram-negative rods , particularly pseudomonas , with high percentage of strains resistant to gentamycin and tobramycin . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
37,
44
]
} | {
"id": "C3714514",
"name": "infections",
"pos": [
83,
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} |
black bears ( ursus americanus ) from 3 geographic areas of california were tested for antibodies against agents of 6 zoonotic diseases : toxoplasmosis ( indirect hemagglutination ) , q fever ( microagglutination ) , trichinosis ( latex particle agglutination ) , botulism ( passive hemagglutination ) , leptospirosis ( ... | nichd_parent_of | {
"id": "C0043528",
"name": "zoonotic diseases",
"pos": [
118,
135
]
} | {
"id": "C0034362",
"name": "q fever",
"pos": [
184,
191
]
} |
black bears ( ursus americanus ) from 3 geographic areas of california were tested for antibodies against agents of 6 zoonotic diseases : toxoplasmosis ( indirect hemagglutination ) , q fever ( microagglutination ) , trichinosis ( latex particle agglutination ) , botulism ( passive hemagglutination ) , leptospirosis ( ... | nichd_parent_of | {
"id": "C0043528",
"name": "zoonotic diseases",
"pos": [
118,
135
]
} | {
"id": "C0040896",
"name": "trichinosis",
"pos": [
217,
228
]
} |
black bears ( ursus americanus ) from 3 geographic areas of california were tested for antibodies against agents of 6 zoonotic diseases : toxoplasmosis ( indirect hemagglutination ) , q fever ( microagglutination ) , trichinosis ( latex particle agglutination ) , botulism ( passive hemagglutination ) , leptospirosis ( ... | nichd_parent_of | {
"id": "C0043528",
"name": "zoonotic diseases",
"pos": [
118,
135
]
} | {
"id": "C0032064",
"name": "plague",
"pos": [
348,
354
]
} |
these findings suggest that increased metaphase/prophase ratios observed in many tumors are due to increases in duration of metaphase rather than to shorter prophases , and that increased mitotic indices commonly observed in malignant tumors and sometimes used as an index of growth rate are at least in part due to the ... | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
81,
87
]
} | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
225,
241
]
} |
when comparing cochleas of different total length , the best predictor of cf at a given location is the distance from base or apex expressed as a percentage of the total length . | nichd_parent_of | {
"id": "C1521970",
"name": "cf",
"pos": [
74,
76
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
170,
176
]
} |
( 1 ) uterine artery ligation on one side on day 18.5 induced large individual variations in fetal and placental weight as well as in placental blood flow . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
68,
78
]
} | {
"id": "C0015965",
"name": "fetal",
"pos": [
93,
98
]
} |
a sensitive method for detecting cells coated with antibodies with human monoclonal rheumatoid factor produced in vitro . | nichd_parent_of | {
"id": "C0003241",
"name": "antibodies",
"pos": [
51,
61
]
} | {
"id": "C0035448",
"name": "rheumatoid factor",
"pos": [
84,
101
]
} |
it is pointed out that blocks of the peripheral as well as the central nervous system should be considered early rather than late in these disease syndromes in order to prevent central fixation . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
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146
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
147,
156
]
} |
ninety-three patients had been hospitalised for early stroke appropriate to the occlusion , and seven for transient ischaemic attacks . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
54,
60
]
} | {
"id": "C0007787",
"name": "transient ischaemic",
"pos": [
106,
125
]
} |
alternatively , the membrane surface of mature oocytes may be altered by the interaction with the substances present in the junctional fluid . | nichd_parent_of | {
"id": "C0439861",
"name": "substances",
"pos": [
98,
108
]
} | {
"id": "C0005889",
"name": "fluid",
"pos": [
135,
140
]
} |
forty-eight percent were for parenchymal tumors , 44 % for mediastinal masses , and 8 % for pleural disease . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
41,
47
]
} | {
"id": "C0240318",
"name": "mediastinal masses",
"pos": [
59,
77
]
} |
the significance of ultrasound examinations in early stages of pregnancy is illustrated by the detection of four severe congenital malformations within the first trimester and one malformation syndrome within the first part of the second trimester of pregnancy . | nichd_parent_of | {
"id": "C0000768",
"name": "congenital malformations",
"pos": [
120,
144
]
} | {
"id": "C1302790",
"name": "malformation syndrome",
"pos": [
180,
201
]
} |
such a finding , on its own , is insufficient justification for recommending a diagnostic tissue biopsy . | nichd_parent_of | {
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"name": "finding",
"pos": [
7,
14
]
} | {
"id": "C0011900",
"name": "diagnostic",
"pos": [
79,
89
]
} |
we found elevated levels of antibody to the streptococcal exotoxin antideoxyribonuclease-b in psoriatic arthritis patients in comparison to patients with psoriasis without arthritis , rheumatoid arthritis , other forms of dermatitis , and normal controls . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
104,
113
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
184,
204
]
} |
we studied 3 groups of hearts : 1 ) fifteen specimens obtained from patients who had no heart disease , 2 ) nine specimens from patients who had expired from cyanotic congenital heart disease , and 3 ) ten specimens from patients who had expired from acute rheumatic heart disease with carditis and severe heart failure ... | nichd_parent_of | {
"id": "C0018799",
"name": "heart disease",
"pos": [
88,
101
]
} | {
"id": "C0018801",
"name": "heart failure",
"pos": [
306,
319
]
} |
only trace to ++ amounts ( on a scale of ++++ ) were found in 20 patients : 4/9 with post-streptococcal acute glomerulonephritis ( gn ) , 5/30 with gn associated with systemic lupus erythematosus , 3/20 with membranous gn , 1/4 with goodpasture 's syndrome , 2/18 with recurrent microhematuria and focal gn , 1/5 with he... | nichd_parent_of | {
"id": "C0017658",
"name": "gn",
"pos": [
131,
133
]
} | {
"id": "C0017665",
"name": "membranous gn",
"pos": [
208,
221
]
} |
only trace to ++ amounts ( on a scale of ++++ ) were found in 20 patients : 4/9 with post-streptococcal acute glomerulonephritis ( gn ) , 5/30 with gn associated with systemic lupus erythematosus , 3/20 with membranous gn , 1/4 with goodpasture 's syndrome , 2/18 with recurrent microhematuria and focal gn , 1/5 with he... | nichd_parent_of | {
"id": "C0017658",
"name": "gn",
"pos": [
131,
133
]
} | {
"id": "C0017661",
"name": "focal gn",
"pos": [
298,
306
]
} |
in addition , a literature survey of this disorder is presented as well as a program for adequate diagnostic evaluation of a patient with a urinary tract disorder . | nichd_parent_of | {
"id": "C0012634",
"name": "disorder",
"pos": [
42,
50
]
} | {
"id": "C0042075",
"name": "urinary tract disorder",
"pos": [
140,
162
]
} |
based on this pathogenesis the following terminology is recommended for central retinal vascular occlusion : ( a ) ischemic retinopathy is due to occlusion of the central retinal artery . | nichd_parent_of | {
"id": "C0035309",
"name": "retinopathy",
"pos": [
124,
135
]
} | {
"id": "C0007688",
"name": "occlusion",
"pos": [
146,
155
]
} |
it is concluded that the measurement of prebeta-beta-lipoportein in cord serum allows the identification of children with familial type ii hyperlipoproteinemia , if infants with transient neonatal hypertriglyceridemia and hypercholesterolemia are excluded . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
108,
116
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
165,
172
]
} |
this procedure was applied to the synthesis of 2',3'-0-isopropylideneguanosine ( xvi ) from the riboside of 5- ( n'-benzoyl-s-methylthiocarbamoyl ) amino-4-imidazolecarboxamide ( ix ) , providing a new route to xvi . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
5,
14
]
} | {
"id": "C0013153",
"name": "route",
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202,
207
]
} |
the two diseases most often confused with this syndrome are rheumatic fever and juvenile rheumatoid arthritis . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
8,
16
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
47,
55
]
} |
it is suggested that localized hypoxia may result in cellular changes that release substances , e.g. , potassium , to the interstitial space where they mobilize fluid and enhance lymph flow . | nichd_parent_of | {
"id": "C0439861",
"name": "substances",
"pos": [
83,
93
]
} | {
"id": "C0005889",
"name": "fluid",
"pos": [
161,
166
]
} |
the tumour is rare , but it is a relevant differential diagnosis in young patients with a hepatic mass . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
4,
10
]
} | {
"id": "C0240225",
"name": "hepatic mass",
"pos": [
90,
102
]
} |
98 arrhythmias were successfully treated in this group , the best results being obtained in ventricular arrhythmias : 16 out of 26 patients with ventricular fibrillation were successfully defibrillated ( 61 % ) , while 47 out of 53 episodes ( 89 % ) of frequent premature ventricular beats and all 9 episodes of ventricu... | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmias",
"pos": [
3,
14
]
} | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
92,
115
]
} |
98 arrhythmias were successfully treated in this group , the best results being obtained in ventricular arrhythmias : 16 out of 26 patients with ventricular fibrillation were successfully defibrillated ( 61 % ) , while 47 out of 53 episodes ( 89 % ) of frequent premature ventricular beats and all 9 episodes of ventricu... | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
92,
115
]
} | {
"id": "C0042510",
"name": "ventricular fibrillation",
"pos": [
145,
169
]
} |
twenty-one forequarter amputations were performed at our institute during a 15 year period for soft tissue sarcoma , osteosarcoma , recurrent malignant melanoma and epidermoid carcinoma . | nichd_parent_of | {
"id": "C1261473",
"name": "soft tissue sarcoma",
"pos": [
95,
114
]
} | {
"id": "C0029463",
"name": "osteosarcoma",
"pos": [
117,
129
]
} |
individual growth curves , grouped according to the weight-for-dates of the newborn child , show a trend towards longer biparietal diameters in the larger fetuses . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
0,
10
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
84,
89
]
} |
though individual growth rates in height can not be closely predicted from the width of the band in normal children and adolescents , in certain clinical conditions the band width may be a useful guide as to whether or not growth is proceeding normally . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
7,
17
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
107,
115
]
} |
the differential diagnosis of cataracts in childhood encompasses a broad and fascinating range of diseases and syndromes . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
98,
106
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
111,
120
]
} |
the association of disseminated lymphoreticular neoplasms with sjogren 's syndrome has been recognized , and the malignancy is usually widespread at the time of diagnosis . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
48,
57
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
113,
123
]
} |
recommended therapeutic doses of either drug did not prevent characteristic mh changes in oxygen consumption , cardiac output , lactate , k+ , ph , catecholamines , or temperature . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
61,
75
]
} | {
"id": "C0039476",
"name": "temperature",
"pos": [
168,
179
]
} |
in 81 cases of toxoplasmosis in patients with neoplasia , collagen-vascular disorders , and organ allografts , the clinical manifestations were highly variable but neurologic syndromes consistent with diffuse encephalopathy , meningoencephalitis , or cerebral mass lesions predominated . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasia",
"pos": [
46,
55
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
260,
264
]
} |
categorizing these two diseases along with fundus albipunctatus as flecked retina syndrome should be continued on the basis of the somewhat similar morphologic appearance of the lesions , rather than because of similar results on functional testing . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
23,
31
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
82,
90
]
} |
in this study we have used experimental models to assess the value of serum antibody , urinary antibody , rheumatoid factor , and the histochemical examination of renal tissue as diagnostic parameters . | nichd_parent_of | {
"id": "C0003241",
"name": "antibody",
"pos": [
76,
84
]
} | {
"id": "C0035448",
"name": "rheumatoid factor",
"pos": [
106,
123
]
} |
in more distant relatives there were 6 with congenital heart disease , including 2 with ventricular septal defects and 2 with fallot 's tetralogy . | nichd_parent_of | {
"id": "C0152021",
"name": "congenital heart disease",
"pos": [
44,
68
]
} | {
"id": "C0039685",
"name": "fallot 's tetralogy",
"pos": [
126,
145
]
} |
a list is given of classes of potential carrier , who should be tested for hepatitis b antigen ( hbag ) , and a procedure is outlined for minimizing the risk to staff engaged on surgical operations on hepatitis carriers . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
112,
121
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
178,
186
]
} |
it is sometimes associated with chronic obstructive pulmonary disease , but has been described most often in patients with gastrointestinal disorders including duodenal and gastric ulceration , small bowel obstruction , regional enteritis and gastrointestinal malignancy . | nichd_parent_of | {
"id": "C0017178",
"name": "gastrointestinal",
"pos": [
123,
139
]
} | {
"id": "C0010346",
"name": "regional enteritis",
"pos": [
220,
238
]
} |
2,3-dihydroxybenzoic acid ( 2,3-dhb ) , a recently identified , orally effective iron-chelating drug , inhibited membrane peroxidation in vitro in h2o2-stressed erythrocytes from patients with beta-thalassaemia major , beta-thalassaemia intermedia , haemoglobin koln disease and sickle cell disease . | nichd_parent_of | {
"id": "C0019045",
"name": "haemoglobin",
"pos": [
250,
261
]
} | {
"id": "C0002895",
"name": "sickle cell disease",
"pos": [
279,
298
]
} |
it has been suggested that the megaloblastic anaemia in pernicious anaemia is due to inadequate intracellular concentration of monoglutamyl folates other than methyltetrahydrofolate caused by diminished conversion of methyltetrahydrofolate to tetrahydrofolate ( methylfolate trap ) . | nichd_parent_of | {
"id": "C0002888",
"name": "megaloblastic anaemia",
"pos": [
31,
52
]
} | {
"id": "C0002892",
"name": "anaemia",
"pos": [
67,
74
]
} |
these observations support ineffective utilization of methyltetrahydrofolate as the major cause of megaloblastic anaemia in pernicious anaemia , but indicate that the degree and location of block varied in different patients , and in different precursor cells of a single patient . | nichd_parent_of | {
"id": "C0002888",
"name": "megaloblastic anaemia",
"pos": [
99,
120
]
} | {
"id": "C0002892",
"name": "pernicious anaemia",
"pos": [
124,
142
]
} |
csf production was found to be variable and was related to the morphologic subtype of aml -- cells from patients with monocytic leukemia produced normal or large quantities of csf , while ( with one exception ) those from patients with myeloblastic leukemia produced little or no csf . | nichd_parent_of | {
"id": "C0023467",
"name": "aml",
"pos": [
86,
89
]
} | {
"id": "C0023479",
"name": "myeloblastic leukemia",
"pos": [
236,
257
]
} |
lymphocytes from normal subjects , from patients having other types of sarcoma , and patients having carcinomas rarely responded to the soluble osteosarcoma antigens . | nichd_parent_of | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
71,
78
]
} | {
"id": "C0029463",
"name": "osteosarcoma",
"pos": [
144,
156
]
} |
there was a 4 % incidence of new tumors in 101 organ homograft recipient- who had had pre-existing cancers . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
33,
39
]
} | {
"id": "C0006826",
"name": "cancers",
"pos": [
99,
106
]
} |
this index was significantly correlated with infarct size index ( isi ) and the strength and significance of the correlation increased when patients with previous , remote myocardial infarction were excluded . | nichd_parent_of | {
"id": "C0021308",
"name": "infarct",
"pos": [
45,
52
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
172,
193
]
} |
it was suggested that several behaviorial factors could be important in allowing mild local symptoms of infection to develop into pid . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
104,
113
]
} | {
"id": "C0242172",
"name": "pid",
"pos": [
130,
133
]
} |
to understand why congenital dislocated hip ( cdh ) was diagnosed late ( mean age : nine months ) in children admitted to the children 's hospital of philadelphia ( chop ) , 714 consecutive chop admissions , aged zero to two years , and 947 consecutive newborns delivered at the hospital , university of pennsylvania ( h... | nichd_parent_of | {
"id": "C0008059",
"name": "children 's",
"pos": [
126,
137
]
} | {
"id": "C0021289",
"name": "newborns",
"pos": [
253,
261
]
} |
malnourished rats presented some of the features commonly found in human protein-energy malnutrition , such as failure to gain weight , hypoalbuminaemia , fatty infiltration of the liver and intolerance of oral and intravenous glucose loads . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
40,
48
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
127,
133
]
} |
clinical signs which began on day 17 were ataxia , dysmetria , blindness , convulsions , paresis , and death . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0011065",
"name": "death",
"pos": [
103,
108
]
} |
petit mal absences in childhood are often followed by grand mal seizures in adolescence and a coexistence of both types of seizures is not uncommon at all . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
22,
31
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
76,
87
]
} |
it is suggested , on the basis of the severity of the clinical symptoms , and on the pathological changes in the rectum , that the organism in this case is likely to have been the cause of the enterocolitis and thus to have been a pathogen rather than a commensal . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
131,
139
]
} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
231,
239
]
} |
hemorrhages which are triggered by a coagulation defect ( consumption coagulopathy ) may be aggravated by the additional loss of coagulation factors . | nichd_parent_of | {
"id": "C0005779",
"name": "coagulation",
"pos": [
37,
48
]
} | {
"id": "C0012739",
"name": "consumption coagulopathy",
"pos": [
58,
82
]
} |
successful operations were performed in 25 children , but in a 12-day old infant the disease was diagnosed only at autopsy . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
43,
51
]
} | {
"id": "C0021270",
"name": "infant",
"pos": [
74,
80
]
} |
643 ano-rectal electromanometric investigations were carried out in 438 children with different ano-rectal diseases including myelomeningocele , hirschsprung 's disease , anal atresia and chronic constipation , as well as in healthy premature , new-born and older infants . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
72,
80
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
264,
271
]
} |
postive rheumatoid factor tests were found in 117 patients with rheumatoid arthritis and in 595 patients with other diseases , exclusive of connective tissue diseases . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
116,
124
]
} | {
"id": "C0009782",
"name": "connective tissue diseases",
"pos": [
140,
166
]
} |
this assumed pathology is divided half in pancreatic causes ( neoplasm , pancreatitis , pseudocysts ) and half in hepatobiliary causes ( metastatic cancer of the liver , cancer of the hilus , cirrhosis , hydatid cyst , alveolar echinococcosis or angioma ) . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasm",
"pos": [
62,
70
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
170,
176
]
} |
this assumed pathology is divided half in pancreatic causes ( neoplasm , pancreatitis , pseudocysts ) and half in hepatobiliary causes ( metastatic cancer of the liver , cancer of the hilus , cirrhosis , hydatid cyst , alveolar echinococcosis or angioma ) . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasm",
"pos": [
62,
70
]
} | {
"id": "C0018916",
"name": "angioma",
"pos": [
246,
253
]
} |
of 41 patients with clinical findings consistent with a diagnosis of ekc and three patients with pharyngoconjunctional fever , 43 were positive by immunofluorescence . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
20,
37
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
56,
65
]
} |
when the organism was inoculated as a suspension in saline , infection infrequently occurred as small ring abscesses of short duration around a few sites of inoculation . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
61,
70
]
} | {
"id": "C0000833",
"name": "abscesses",
"pos": [
107,
116
]
} |
when the organism was inoculated as a suspension in a solution of gastric mucin , infection was usually observed as severe hypopyon-keratitis with formation of a huge ring abscess . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
82,
91
]
} | {
"id": "C0000833",
"name": "abscess",
"pos": [
172,
179
]
} |
the ability of the procedure to identify histoplasma spp . was evaluated by testing 96 unknown mycelial cultures that grossly or microscopically resembled histoplasma spp . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
19,
28
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
63,
72
]
} |
incorporation is completely prevented if the organisms are reacted wiith fresh serum from animals immunized with gamma-irradiated parasites ; | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
45,
54
]
} | {
"id": "C0030498",
"name": "parasites",
"pos": [
130,
139
]
} |
a method is described for the resolution and individual quantitation of cortisol , cortisone , 11-deoxycortisol and corticosterone in foetal sheep plasma . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
45,
55
]
} | {
"id": "C0015965",
"name": "foetal",
"pos": [
134,
140
]
} |
there were 13 malignant tumours in the series : five fibrosarcomas , five liposarcomas , two rhabdomyosarcomas and one undifferentiated ( pleomorphic ) sarcoma . | nichd_parent_of | {
"id": "C0006826",
"name": "malignant tumours",
"pos": [
14,
31
]
} | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
152,
159
]
} |
this procedure has been duplicated for clinical patients with reasonably good results , restoring function in otherwise untenable prosthetic situations whic had been refractory to other types of prosthetic and surgical treatment . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
5,
14
]
} | {
"id": "C0543467",
"name": "surgical treatment",
"pos": [
210,
228
]
} |
another argument for the usefulness of this test for genetic analysis was the fact that , though mouse mammary tumor virus ( mumtv ) of the gr strain was introduced into balb/c and tmas mice by foster-nursing , ant treatment did not lead to emt . | nichd_parent_of | {
"id": "C0022885",
"name": "test",
"pos": [
44,
48
]
} | {
"id": "C0679560",
"name": "genetic analysis",
"pos": [
53,
69
]
} |
the histologic type ( descending range in malignancy : sarcomas greater than simple carcinomas greater than complex carcinomas ) , mode of growth ( highly infiltrating greater than moderately infiltrating greater than expansive ) , clinical stage of complex carcinomas ( large tumors and/or tumors involving the skin or ... | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
42,
52
]
} | {
"id": "C1261473",
"name": "sarcomas",
"pos": [
55,
63
]
} |
in addition , endotoxin-treated swine developed signs of disseminated intravascular coagulation , with renal cortical infarcts in 44 % , and coronary arterial thrombi in 28 % including one transmural myocardial infarction . | nichd_parent_of | {
"id": "C0021308",
"name": "infarcts",
"pos": [
118,
126
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
200,
221
]
} |
this procedure had several advantages as compared to treatments with nonionic or ionic detergents : ( i ) the solubilized enzyme was stable at 4 c , ( ii ) more than 80 % of the replicase could be solubilized without loss of total enzyme activity , ( iii ) the replicase was rather selectively released resulting in a tw... | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
5,
14
]
} | {
"id": "C0087111",
"name": "treatments",
"pos": [
53,
63
]
} |
almost all obstetric departments have abandoned their central milk-kitchens and provide fluid nourishment except where they are connected with the central milk-kitchen of a paediatric department . | nichd_parent_of | {
"id": "C0005889",
"name": "fluid",
"pos": [
88,
93
]
} | {
"id": "C0026131",
"name": "milk",
"pos": [
155,
159
]
} |
2 batches of baboon infected with tuberculosis were subjected to serial tests with human and bovine tuberculin , while erythrocyte sedimentation rates were estimated concurrently . | nichd_parent_of | {
"id": "C0022885",
"name": "tests",
"pos": [
72,
77
]
} | {
"id": "C1176468",
"name": "erythrocyte sedimentation rates",
"pos": [
119,
150
]
} |
after further development of the disease , tuberculin tests remained positive while sedimentation rates were raised by 10-30 mm per hour . | nichd_parent_of | {
"id": "C0022885",
"name": "tests",
"pos": [
54,
59
]
} | {
"id": "C1176468",
"name": "sedimentation rates",
"pos": [
84,
103
]
} |
wide surgical exposure , total tumor removal and anatomic and functional reconstruction are the goals of tumor management . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical",
"pos": [
5,
13
]
} | {
"id": "C0015250",
"name": "total",
"pos": [
25,
30
]
} |
after recalling the latest finding on the pathological anatomy , physiopathology , symptomatology , diagnosis and surgical therapy of hepatic echinococcus with intrahepatic bile duct fistulas , the personal series and that of the palermo surgical pathology school is illustrated . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
27,
34
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
100,
109
]
} |
there were 21 boot top fractures , 20 spiral fractures of the tibial shaft , eight malleolar fractures , and one fracture of the lateral tuberosity of the tibia . | nichd_parent_of | {
"id": "C0016658",
"name": "fractures",
"pos": [
23,
32
]
} | {
"id": "C0040185",
"name": "fractures",
"pos": [
93,
102
]
} |
among boot top fractures cases , boys younger than 20 years predominated much more than among patients with other fractures of the tibial shaft . | nichd_parent_of | {
"id": "C0016658",
"name": "fractures",
"pos": [
15,
24
]
} | {
"id": "C0040185",
"name": "fractures",
"pos": [
114,
123
]
} |
the factors were : career desirability , professional attitude , professional behavior , achievement personality , conducive home situation , economic value of work , and satisfaction with nursing . | nichd_parent_of | {
"id": "C0004927",
"name": "behavior",
"pos": [
78,
86
]
} | {
"id": "C0006147",
"name": "nursing",
"pos": [
189,
196
]
} |
when the seven factors were correlated with employment status while controlling financial need and age of youngest child at home , highest correlation scores resulted for professional behavior , career desirability , and , in the case of those with financial need , on the economic value of nursing . | nichd_parent_of | {
"id": "C0004927",
"name": "behavior",
"pos": [
184,
192
]
} | {
"id": "C0006147",
"name": "nursing",
"pos": [
291,
298
]
} |
the influence of n1-substituents both on the so2 electronic features and on the coupling between the para amino group and the phenyl ring was discussed . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
60,
68
]
} | {
"id": "C0030563",
"name": "para",
"pos": [
101,
105
]
} |
nine of this group of 53 patients had both anaemia and an increased mcv -- the macrocytic anaemia of hypothyroidism . | nichd_parent_of | {
"id": "C0002871",
"name": "anaemia",
"pos": [
43,
50
]
} | {
"id": "C0002886",
"name": "macrocytic",
"pos": [
79,
89
]
} |
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