text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
the content and distribution of hemosiderin in the liver , spleen and lungs of stillborn children , newborns and infants were determined histologically by perl 's method ( prussian blue reaction ) . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
89,
97
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
113,
120
]
} |
after decades of morphological , biochemical , experimental , epidemiological and clinical studies it is still not possible to throw light on the pathogenesis of coronary disease , in particular on that of the heart attack . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
142,
145
]
} | {
"id": "C0027051",
"name": "heart attack",
"pos": [
210,
222
]
} |
in the remaining 2 cases one was misdiagnosed as a small cell carcinoma and the other one raised suspicion of malignancy ( pap-iii-finding ) , but no definitive diagnosis could be made . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
131,
138
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
161,
170
]
} |
the postoperative rate of unilateral nerve palsy recurrence has been reduced from 4.47 to 2.20 per cent , whereas other complications remained unchanged , such as postoperative bleeding and thyreotoxicosis . | nichd_parent_of | {
"id": "C0009566",
"name": "complications",
"pos": [
120,
133
]
} | {
"id": "C0032788",
"name": "postoperative bleeding",
"pos": [
163,
185
]
} |
with the use of a system of serological reactions ( phar ) on the basis of erythrocytic diagnosticums in neurosurgical patients ( 58 with tumors of the brain , 11 with tumors of the spinal cord , 112 with tumor-like diseases of the brain , 50 with lesions of the spinal cord marked by a tumor-like course ) and in a cont... | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
216,
224
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
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588
]
} |
in the present investigation we have attempted to clarify the importance of the experimental procedure when evaluating the influence of anaesthetics on the secretion of prl and lh in male rats . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
93,
102
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
108,
118
]
} |
however , as there are a number of recurring , consistent chromosomal abnormalities in neoplasia , patients with aids should also be evaluated for chromosomal aberrations , especially in light of the increased number of secondary malignancies being described in such patients . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasia",
"pos": [
87,
96
]
} | {
"id": "C0006826",
"name": "malignancies",
"pos": [
230,
242
]
} |
both women and men had a significant increase in the mortality of subarachnoidal hemorrhages , and a significant fall in the mortality of intracerebral hemorrhages . | nichd_parent_of | {
"id": "C0019080",
"name": "hemorrhages",
"pos": [
81,
92
]
} | {
"id": "C2937358",
"name": "intracerebral hemorrhages",
"pos": [
138,
163
]
} |
two types of langerhans ' cells were found , one is positive for ferritin and alpha-2-macroglobulin in diffuse histiocytosis-x cells , and another is negative for them in both eosinophilic granulomas . | nichd_parent_of | {
"id": "C0019621",
"name": "histiocytosis-x",
"pos": [
111,
126
]
} | {
"id": "C0014461",
"name": "eosinophilic",
"pos": [
176,
188
]
} |
diffuse histiocytosis-x cell resembled the transformed type of langerhans cell more than eosinophilic granuloma cells in cellular differentiation . | nichd_parent_of | {
"id": "C0019621",
"name": "histiocytosis-x",
"pos": [
8,
23
]
} | {
"id": "C0014461",
"name": "eosinophilic granuloma",
"pos": [
89,
111
]
} |
a similarly hypersensitive reaction to the foreign maternal protein which may enter the foetal circulation is suggested as the cause of hydrocephalus in some of the cases of congenital hydrocephalus . | nichd_parent_of | {
"id": "C0020255",
"name": "hydrocephalus",
"pos": [
136,
149
]
} | {
"id": "C0020256",
"name": "congenital hydrocephalus",
"pos": [
174,
198
]
} |
the advantages of this method are as follows : simple procedure , quick operation , sufficient stability and easy removal of the implants particularly in elderly patients . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
54,
63
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
72,
81
]
} |
we suggest laser photocoagulation as the palliative treatment of choice for dysphagia due to oesophagogastric tumour in the frail elderly patient even when the malignancy is at an advanced stage . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
110,
116
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
160,
170
]
} |
the possible involvement of this molecule in the pathogenesis of chronic erosive arthritis has been investigated using an animal model , antigen-induced arthritis in the rabbit , which closely resembles rheumatoid arthritis . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
81,
90
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
203,
223
]
} |
in contrast , release of myosin light chains was not significantly changed by recanalization of the infarct-related artery compared with that in nonreperfused myocardial infarction . | nichd_parent_of | {
"id": "C0021308",
"name": "infarct",
"pos": [
100,
107
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
159,
180
]
} |
ninety-five patients suspected of having multiple sclerosis ( ms ) were evaluated by medical history and neurologic examination . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
72,
81
]
} | {
"id": "C0027853",
"name": "neurologic examination",
"pos": [
105,
127
]
} |
in addition , the availability of distribution curves in children based on repeated observations , and using phase v of korotkoff sound for the diastolic blood pressures , would be particularly helpful during the transition period from childhood to adolescence . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
236,
245
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
249,
260
]
} |
our observation suggest that aml with t ( 6 ; 9 ) ( p23 ; q34 ) is characterized by myelodysplasia , basophilia , and a variety of blast cell morphologies ( m1 , m2 , m4 ) with a greater proportion of the cases than previously appreciated being examples of acute myelomonocytic leukemia ( aml-m4 ) . | nichd_parent_of | {
"id": "C0023467",
"name": "aml",
"pos": [
29,
32
]
} | {
"id": "C0023479",
"name": "aml-m4",
"pos": [
289,
295
]
} |
to evaluate the usefulness of clinical and routine laboratory findings in the diagnosis of hypothyroidism in patients with esrd , we compared 6 patients with documented primary hypothyroidism who had serum thyrotrophin ( tsh ) levels above 20 microu/ml with 12 euthyroid patients . | nichd_parent_of | {
"id": "C0020676",
"name": "hypothyroidism",
"pos": [
91,
105
]
} | {
"id": "C0700502",
"name": "primary hypothyroidism",
"pos": [
169,
191
]
} |
29 gn patients with normal renal function ( 17 membranoproliferative gn , 12 iga gn ) were randomly assigned to receive 100 mg/day of diclofenac or placebo for at least 2 months . | nichd_parent_of | {
"id": "C0017658",
"name": "gn",
"pos": [
3,
5
]
} | {
"id": "C0017662",
"name": "membranoproliferative gn",
"pos": [
47,
71
]
} |
29 gn patients with normal renal function ( 17 membranoproliferative gn , 12 iga gn ) were randomly assigned to receive 100 mg/day of diclofenac or placebo for at least 2 months . | nichd_parent_of | {
"id": "C0017658",
"name": "gn",
"pos": [
3,
5
]
} | {
"id": "C0017661",
"name": "iga gn",
"pos": [
77,
83
]
} |
there was not a statistically significant difference ( p less than 0.53 ) in pregnancy complications or in late complications between the two groups although oligohydramnios and abdominal pregnancies occurred more often in the study group ( p less than 0.029 and less than 0.011 ) . | nichd_parent_of | {
"id": "C0032962",
"name": "pregnancy complications",
"pos": [
77,
100
]
} | {
"id": "C0079924",
"name": "oligohydramnios",
"pos": [
158,
173
]
} |
we interviewed 603 elderly hispanic women residing in los angeles to evaluate the usefulness of cultural factors as predictors of preventive health behavior ( e.g. , physical examination , screening for breast cancer ) more rigorously . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
69,
77
]
} | {
"id": "C0031809",
"name": "physical examination",
"pos": [
166,
186
]
} |
it is emphasized that only the finding of rocha-lima 's inclusions on light-microscopic studies and/or the demonstration of bartonella organisms in the lesions by electron-microscopic studies can objectively establish a diagnosis in a given lesion . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
31,
38
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
220,
229
]
} |
fetal growth retardation and an increased incidence of the complications of pre-eclampsia and neonatal hyperbilirubinemia at high altitude suggested that altitude may aggravate complications of pregnancy and prenatal life . | nichd_parent_of | {
"id": "C0009566",
"name": "complications",
"pos": [
59,
72
]
} | {
"id": "C0032962",
"name": "complications of pregnancy",
"pos": [
177,
203
]
} |
the most common organisms recovered in addition to the primary pathogen was alpha hemolytic streptococci . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
16,
25
]
} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
63,
71
]
} |
the etiology of the edema is uncertain , but concurrent hyponatremia and cerebral edema were present in this patient , as in 2 previously reported cases , suggesting that neurogenic pulmonary edema caused by water intoxication may be a contributing factor in pathogenesis . | nichd_parent_of | {
"id": "C0013604",
"name": "edema",
"pos": [
20,
25
]
} | {
"id": "C0006114",
"name": "cerebral edema",
"pos": [
73,
87
]
} |
there were 159 tumors with the potential for producing various ectopic hormones as well as biologically active amines , including 112 oat cell carcinomas , 37 carcinoid tumors , 4 paragangliomas , 2 pancreatic islet cell tumors , 2 medullary thyroid carcinomas , 1 pituitary adenoma , and 1 pinealocytoma . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
15,
21
]
} | {
"id": "C0032000",
"name": "pituitary adenoma",
"pos": [
265,
282
]
} |
the initial presentation of scleroderma ( systemic sclerosis ) with a manifestation involving only the breast has not been reported in the literature . | nichd_parent_of | {
"id": "C0011644",
"name": "scleroderma",
"pos": [
28,
39
]
} | {
"id": "C0036421",
"name": "systemic sclerosis",
"pos": [
42,
60
]
} |
in migraine the csf is normal or may show an isolated increase in protein content ( with the exception of the very rare familial hemiplegic migraine ) . | nichd_parent_of | {
"id": "C0149931",
"name": "migraine",
"pos": [
3,
11
]
} | {
"id": "C0338484",
"name": "familial hemiplegic migraine",
"pos": [
120,
148
]
} |
the indication for re-operation must in part reflect the nature of surgical practice but in this general surgical unit the most common complications requiring re-laparotomy were sepsis , small bowel obstruction and wound dehiscence . | nichd_parent_of | {
"id": "C0009566",
"name": "complications",
"pos": [
135,
148
]
} | {
"id": "C0259768",
"name": "wound dehiscence",
"pos": [
215,
231
]
} |
when tumors were classified according to histological type , intratumoral 5-fu concentration was not always correlated with degeneration of cancer cells . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
5,
11
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
140,
146
]
} |
the primary tumors included thymic neoplasms ( 17 % ) , neurogenic tumors ( 14 % ) , lymphoma ( 16 % ) , germ cell tumors ( 11 % ) , and a miscellaneous group . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
12,
18
]
} | {
"id": "C0205851",
"name": "germ cell tumors",
"pos": [
105,
121
]
} |
the majority of tumors 58 % cases present themselves as bulky masses exceeding 6 cm of diameter . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
16,
22
]
} | {
"id": "C0577559",
"name": "masses",
"pos": [
62,
68
]
} |
the nf proteins are good markers for pheochromocytoma , and their presence is of basic tumor biologic interest and of potential diagnostic value in other neuroendocrine neoplasms . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
87,
92
]
} | {
"id": "C0206754",
"name": "neuroendocrine neoplasms",
"pos": [
154,
178
]
} |
acceptable observer reliability was achieved for ten clinical signs that were factor-analyzed to suggest three dimensions of motor performance : ambulation , tremor , and animation . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
53,
67
]
} | {
"id": "C0040822",
"name": "tremor",
"pos": [
158,
164
]
} |
the combination of initial muscular inflammation and enlargement , subsequent fibrosis and restricted extraocular motility , and histologic evidence of these changes creates a useful model of orbital myositis . | nichd_parent_of | {
"id": "C0027121",
"name": "muscular inflammation",
"pos": [
27,
48
]
} | {
"id": "C2350476",
"name": "orbital myositis",
"pos": [
192,
208
]
} |
seven of the dogs developed clinical signs of the disease , died and were subjected to a post-mortem examination , while the eighth dog remained normal . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
28,
42
]
} | {
"id": "C0011065",
"name": "died",
"pos": [
60,
64
]
} |
the preferential induction of the gst isoenzymes involved in the detoxification of activated b [ a ] p metabolites indicates that the anti-neoplastic activity of bha against b [ a ] p-induced neoplasia in mouse lung [ wattenberg ( 1973 ) j. natl . cancer inst . 50 , 1541-1544 ] may be due to the enhanced detoxification... | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasia",
"pos": [
192,
201
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
248,
254
]
} |
during the eighteenth biennial examination , we evaluated the cohort members for oa of the knee by use of medical history , physical examination , and anteroposterior ( standing ) radiograph of the knees . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
48,
57
]
} | {
"id": "C0031809",
"name": "physical examination",
"pos": [
124,
144
]
} |
the effect of initial apgar score on the birthweight-specific survival of the very low-birthweight infant . | nichd_parent_of | {
"id": "C0005612",
"name": "birthweight",
"pos": [
41,
52
]
} | {
"id": "C0282666",
"name": "birthweight",
"pos": [
87,
98
]
} |
gestational age ( ga ) and birthweight ( bw ) specific neonatal survival statistics were generated to examine the possible effect of one-minute apgar score on outcome in very low birthweight ( vlbw ) infants . | nichd_parent_of | {
"id": "C0005612",
"name": "birthweight",
"pos": [
27,
38
]
} | {
"id": "C0282666",
"name": "very low birthweight",
"pos": [
170,
190
]
} |
the actuarial survival for all patients was 53 % at 6 years , with 79 % survival for nonsevere aplastic anemia ( nsaa ) and 36 % for severe aplastic anemia ( saa ) . | nichd_parent_of | {
"id": "C0002874",
"name": "aplastic anemia",
"pos": [
95,
110
]
} | {
"id": "C1883018",
"name": "severe aplastic anemia",
"pos": [
133,
155
]
} |
of those convicted of indecent assault on persons under 16 and of gross indecency with children , 48 % had a previous history of psychiatric disorder . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
42,
49
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
87,
95
]
} |
if disease in the femoral triangle extended above the inguinal ligament the tumour 's operability was seriously questioned . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
3,
10
]
} | {
"id": "C0027651",
"name": "tumour 's",
"pos": [
76,
85
]
} |
these findings suggest that the humoral response to r. equi whole-cell antigens is unimportant in protection against disease , which is consistent with the behavior of the organism as a facultative intracellular pathogen . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
172,
180
]
} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
212,
220
]
} |
clinical signs of pyrexia , depression , frequent swallowing , facial fasciculations , chorea , excessive salivation , mild tympanites , labored breathing and focal pruritus were followed by death macroscopic lesions were severe focal facial trauma , petechiae in cervicothoracic ganglia and dilated esophaguses . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0015967",
"name": "pyrexia",
"pos": [
18,
25
]
} |
clinical signs of pyrexia , depression , frequent swallowing , facial fasciculations , chorea , excessive salivation , mild tympanites , labored breathing and focal pruritus were followed by death macroscopic lesions were severe focal facial trauma , petechiae in cervicothoracic ganglia and dilated esophaguses . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0553668",
"name": "labored breathing",
"pos": [
137,
154
]
} |
clinical signs of pyrexia , depression , frequent swallowing , facial fasciculations , chorea , excessive salivation , mild tympanites , labored breathing and focal pruritus were followed by death macroscopic lesions were severe focal facial trauma , petechiae in cervicothoracic ganglia and dilated esophaguses . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0033774",
"name": "pruritus",
"pos": [
165,
173
]
} |
clinical signs of pyrexia , depression , frequent swallowing , facial fasciculations , chorea , excessive salivation , mild tympanites , labored breathing and focal pruritus were followed by death macroscopic lesions were severe focal facial trauma , petechiae in cervicothoracic ganglia and dilated esophaguses . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0011065",
"name": "death",
"pos": [
191,
196
]
} |
in 49 of 52 cases in which the procedure had been performed more than 2 years previously , the patients were happy they had had the operation . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
31,
40
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
132,
141
]
} |
among patients with grade 3 sarcomas , rhabdomyosarcoma ( five of 14 ) , vascular sarcoma ( two of five ) , and epithelioid sarcoma ( four of five ) were associated with a higher incidence of lymph node involvement than synovial sarcomas ( zero of four ) , fibrosarcomas ( zero of 16 ) , malignant fibrohistiocytomas ( o... | nichd_parent_of | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
28,
35
]
} | {
"id": "C0016057",
"name": "fibrosarcomas",
"pos": [
338,
351
]
} |
two patients died of disseminated disease 8 months and 1 year , respectively , after the diagnosis and the third was free of tumor after 18 months . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
34,
41
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
125,
130
]
} |
in these studies soft tissue sarcoma cases have been identified from either deaths with malignant neoplasms of the connective tissue ( icd-8 171 ) as the underlying cause of death , from incident cancer cases with the same topography code , or from incident cases of extraskeletal sarcomas , excluding lympho and reticul... | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
196,
202
]
} | {
"id": "C1261473",
"name": "sarcomas",
"pos": [
321,
329
]
} |
we propose that aberrant expression of marker genes in tumors may be related to their proximity in the human genome to oncogenes expressed during the development of malignancy , and we suggest ways to test this hypothesis of concerted abnormal gene expression in mammalian tumor cells . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
55,
61
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
165,
175
]
} |
after supplying introductory data on the diffusion of the disease , risk factors and statistical aspects , the authors report data on 137 cases of large bowel carcinomatous neoplasms observed and treated over the period 1978-1984 , complete with tables summarising the neoplastic localizations aid the types of operation... | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
58,
65
]
} | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
173,
182
]
} |
in patients with mitral regurgitation spurting from the posteromedial area of the valve , the inferior wall was involved in infarction without exception and in some of these patients , the posteromedial papillary muscle was also found to be affected by myocardial infarction ; | nichd_parent_of | {
"id": "C0021308",
"name": "infarction",
"pos": [
124,
134
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
253,
274
]
} |
dna restriction fragment length polymorphisms ( rflps ) are used for diagnosis of genetic disease in families known to be affected by specific disorders , but rflps can be also useful for the differential diagnosis of hereditary disease . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
143,
152
]
} | {
"id": "C0019247",
"name": "hereditary disease",
"pos": [
218,
236
]
} |
ct showed a better sensitivity than conventional x-ray analysis in the evaluation of the articular space alterations in psoriatic and colitic arthritis as well as in detecting erosions and ankylosis of sacroiliac joints in patients with ankylosing spondylitis or psoriatic arthritis . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
142,
151
]
} | {
"id": "C0003872",
"name": "psoriatic arthritis",
"pos": [
263,
282
]
} |
we have reported that sera from a majority of patients with non-insulin-dependent diabetes mellitus ( niddm ) inhibit insulin-stimulated lipogenesis ( 3-3h-glucose conversion to 3h-lipid ) in rat adipocytes to a greater extent than control sera or sera from patients with insulin-dependent diabetes mellitus ( iddm ) . | nichd_parent_of | {
"id": "C0011849",
"name": "non-insulin-dependent diabetes mellitus",
"pos": [
60,
99
]
} | {
"id": "C0011854",
"name": "insulin-dependent diabetes",
"pos": [
272,
298
]
} |
scdm is etiologically heterogeneous , it has dissimilar etiologies as compared to iddm , and it is unlikely that viral infections play a causal role . | nichd_parent_of | {
"id": "C0011849",
"name": "scdm",
"pos": [
0,
4
]
} | {
"id": "C0011854",
"name": "iddm",
"pos": [
82,
86
]
} |
for these reasons , it is concluded that the finding of a similar seasonal incidence in scdm and iddm suggests that the seasonal incidence of iddm most likely represents the effects of , as yet undefined , stresses which precipitate the diabetic state in humans and dogs with pre-existent islet dysfunction of varying ca... | nichd_parent_of | {
"id": "C0011849",
"name": "scdm",
"pos": [
88,
92
]
} | {
"id": "C0011854",
"name": "iddm",
"pos": [
142,
146
]
} |
the limulus test on lumbar csf was positive in 67 % of cases with other gram-negative bacillary meningitis , in 33 % of cases with gram-negative bacillary abscess or ventriculitis , in none of the cases with gram-positive , mycobacterial , treponemal , fungal , or viral meningitis , and in 1 % of cases with either norm... | nichd_parent_of | {
"id": "C0025289",
"name": "meningitis",
"pos": [
96,
106
]
} | {
"id": "C0025297",
"name": "viral meningitis",
"pos": [
265,
281
]
} |
in this series , clinical characteristics were : bronchial obstruction when the tumor protrudes into the lumen and infection , first in the bronchus ( bronchitis or bronchiectasis ) then in the parenchyma ( acute , recurrent or chronic pneumonia , tension abscess ) . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
115,
124
]
} | {
"id": "C0000833",
"name": "abscess",
"pos": [
256,
263
]
} |
thiazolidine-4-carboxylic acid ( tc ) ( a precursor of intracellular cysteine ) was administered to rats at 50 mg/kg and at 400 mg/kg by an i.p . route and at 800 mg/kg per os , and the levels of glutathione ( gsh ) in gastric mucosa , gastric wall and liver were determined . | nichd_parent_of | {
"id": "C0013153",
"name": "route",
"pos": [
146,
151
]
} | {
"id": "C1527415",
"name": "per os",
"pos": [
169,
175
]
} |
acquired immunodeficiency syndrome ( hiv ) , although not necessarily a gynecologic infection , is included herein because of its sexually transmitted disease potential , and a perspective on protection for the emergency department worker is given . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
84,
93
]
} | {
"id": "C0036916",
"name": "sexually transmitted disease",
"pos": [
130,
158
]
} |
the purpose of the present study was to evaluate the relationship between several physical fitness parameters and eyesight divided into 3 grades in visually handicapped boys and young male adults , and to investigate the effect of mild exercise training on physical and psychic symptoms as well as cardiorespiratory fitn... | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
40,
48
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
257,
265
]
} |
females heterozygous for the x-linked urea cycle disorder , ornithine transcarbamylase ( otc ) deficiency have a significant risk of developing hyperammonaemia . | nichd_parent_of | {
"id": "C0154246",
"name": "urea cycle disorder",
"pos": [
38,
57
]
} | {
"id": "C0268542",
"name": "ornithine",
"pos": [
60,
69
]
} |
vp-16 in advanced soft tissue sarcoma : a phase ii study of the eortc soft tissue and bone sarcoma group . | nichd_parent_of | {
"id": "C1261473",
"name": "soft tissue sarcoma",
"pos": [
18,
37
]
} | {
"id": "C0029463",
"name": "bone sarcoma",
"pos": [
86,
98
]
} |
use of the b5 test in conjunction with erythrocyte sedimentation rate ( esr ) gave an increased specificity for active disease in that 87 % ( 35/40 ) of those who were b5-positive together with a raised esr had active disease : of those patients who were both b5-negative and had normal esr , 9 out of 108 ( 8 % ) had ac... | nichd_parent_of | {
"id": "C0022885",
"name": "test",
"pos": [
14,
18
]
} | {
"id": "C1176468",
"name": "erythrocyte sedimentation rate",
"pos": [
39,
69
]
} |
these findings suggest a role for the b5 test , combined with the esr , in the monitoring of patients with malignant lymphoma . | nichd_parent_of | {
"id": "C0022885",
"name": "test",
"pos": [
41,
45
]
} | {
"id": "C1176468",
"name": "esr",
"pos": [
66,
69
]
} |
thirty quinolizidinyl derivatives , together with two dialkylaminoalkyl analogues , were tested at concentration up to 160 mg/l for antimicrobial activity against 17 microrganisms , including gram-positive and gram-negative strains , mycobac , tuberculosis , trichom , vaginalis , fungi and yeasts . | nichd_parent_of | {
"id": "C0016832",
"name": "fungi",
"pos": [
281,
286
]
} | {
"id": "C0043393",
"name": "yeasts",
"pos": [
291,
297
]
} |
concerning the gram-negative bacteria , activity is found only against escherichia coli and is random and usually slight , as is that against fungi , yeasts and protozoa . | nichd_parent_of | {
"id": "C0016832",
"name": "fungi",
"pos": [
142,
147
]
} | {
"id": "C0043393",
"name": "yeasts",
"pos": [
150,
156
]
} |
diabetic glomerulosclerosis was present in all 13 patients , but 9 patients had a non-diabetic renal disease superimposed ( mesangioproliferative glomerulonephritis ( n = 5 ) , membranous glomerulonephritis ( n = 3 ) and sarcoidosis ( n = 1 ) . | nichd_parent_of | {
"id": "C0017658",
"name": "glomerulonephritis",
"pos": [
146,
164
]
} | {
"id": "C0017665",
"name": "membranous glomerulonephritis",
"pos": [
177,
206
]
} |
we analyse our recent experience with this procedure in three patients and we describe the main advantages and the wide surgical indications with reference to the rastelli procedure . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
43,
52
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
120,
128
]
} |
laparoscopy has a significant yield in patients with a negative ct and is the procedure of choice in evaluating these patients . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
78,
87
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
101,
111
]
} |
twenty-eight subjects were normal and 59 patients were affected by carotid occlusive disease , vascular retinopathies with and without macular involvement , and connective tissue diseases treated with antimalarial drugs . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
85,
92
]
} | {
"id": "C0009782",
"name": "connective tissue diseases",
"pos": [
161,
187
]
} |
to evaluate the usefulness of the test result the following population groups were studied : 1376 patients undergoing medical examination for gonorrhoea ( 386 had gonorrhoea ) , 1384 healthy people aged 15-65 , 54 patients with meningococcal disease , 30 children with respiratory tract infection , and 254 patients with... | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
191,
197
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
255,
263
]
} |
the numbers of viable s. mutans organisms in dental plaque and whole saliva decreased after each series of immunizations , which correlated with increased levels of iga antibodies in saliva , suggesting that iga antibodies in saliva were responsible for the reduced adherence of this bacterium . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
32,
41
]
} | {
"id": "C0004611",
"name": "bacterium",
"pos": [
284,
293
]
} |
the total number of sertoli cells per individual increased significantly from a median of 260 x 10 ( 6 ) ( 130-520 ) during the late foetal period to 1500 x 10 ( 6 ) ( 850-2900 ) in individuals from 3 months to 10 years of age . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
38,
48
]
} | {
"id": "C0015965",
"name": "foetal",
"pos": [
133,
139
]
} |
each surgeon received semiannual reports of 1 ) overall infection rate by site , 2 ) number of surgical wound infections by wound class and type of procedure , 3 ) pathogens for each deep and incisional infection , and 4 ) quarterly wound infection rates by wound class . | nichd_parent_of | {
"id": "C3714514",
"name": "infections",
"pos": [
110,
120
]
} | {
"id": "C0043241",
"name": "wound",
"pos": [
258,
263
]
} |
where childhood diseases tended to occur nearer adolescence , ms frequency in that population was high . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
6,
15
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
48,
59
]
} |
the possible association of ms with some viral infections supposed to be cause/s of ms ( measles , herpes virus type 1 and 2 , mononucleosis ) ; | nichd_parent_of | {
"id": "C0042769",
"name": "viral infections",
"pos": [
41,
57
]
} | {
"id": "C0021345",
"name": "mononucleosis",
"pos": [
127,
140
]
} |
clinical signs included epiphora , facial swelling , dyspnea , unilateral serosanguineous nasal discharge , or an external mass . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0013404",
"name": "dyspnea",
"pos": [
53,
60
]
} |
intermittent severe pigmenturia concomitant with weakness , lethargy , and anorexia were the major clinical signs and commonly were related to exercise or other stressful situations that caused panting or barking ( hyperventilation ) . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
99,
113
]
} | {
"id": "C0020578",
"name": "hyperventilation",
"pos": [
215,
231
]
} |
the various features delineated , including the length of the carboxypeptidase y-sensitive region , the extracellular location of the trypsin-sensitive site , the location of the sites of phosphorylation and glycosylation all constrain the receptor to a rhodopsin-like structure with multiple membrane spanning segments ... | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
12,
20
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
48,
54
]
} |
at birth measurements of weight , length and head circumference were under the 3rd percentile for 13/86 ( 15 % ) , 9/86 ( 10.5 % ) and 9/86 ( 10.5 % ) respectively . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
34,
40
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
45,
63
]
} |
by 2 years of age , weight , length and head circumference were under the 3rd percentile in 23/83 ( 27.7 % ) , 26/83 ( 31.3 % ) and 4/83 ( 4.8 % ) respectively . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
29,
35
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
40,
58
]
} |
measures of phase delays as a function of interelectrode distance supported the development of a 'two-compartmental ' model of eeg coherence in which different features of coherence are produced by different length fiber systems . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
160,
168
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
208,
214
]
} |
for each patient , these seizures had the same clinical and electrographic onset as their partial seizures . | nichd_parent_of | {
"id": "C0036572",
"name": "seizures",
"pos": [
25,
33
]
} | {
"id": "C0751495",
"name": "partial seizures",
"pos": [
90,
106
]
} |
persons with epilepsy demonstrate more emotional and psychiatric problems than normal individuals and more difficulties than other patient groups having nonneurological disorders , but have about the same incidence of these problems as persons with other neurological disorders . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
169,
178
]
} | {
"id": "C0027765",
"name": "neurological disorders",
"pos": [
255,
277
]
} |
mapping experiments , in which 60 to 98 electrograms were simultaneously recorded during spontaneous ventricular arrhythmias demonstrated that ventricular tachycardia is due to macro-re-entry with the re-entrant pathway having a wavelength of the order of 6 cm . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
101,
124
]
} | {
"id": "C0042514",
"name": "ventricular tachycardia",
"pos": [
143,
166
]
} |
group a , 836 patients without a previous mi showing exercise-induced myocardial ischaemia associated with st-segment depression -- group b , 72 patients without a previous mi and exercise-induced st-segment elevation -- group c , 50 patients survivors of a recent ( 1 month ) mi and exercise-induced st-segment depressi... | nichd_parent_of | {
"id": "C0021308",
"name": "mi",
"pos": [
42,
44
]
} | {
"id": "C0027051",
"name": "mi",
"pos": [
361,
363
]
} |
furthermore va in groups b and c were more frequently complex ( couplets , triplets , ventricular tachycardia and fibrillation ) . | nichd_parent_of | {
"id": "C0085612",
"name": "va",
"pos": [
12,
14
]
} | {
"id": "C0042514",
"name": "ventricular tachycardia",
"pos": [
86,
109
]
} |
twenty-one patients from group 1 showed life threatening arrhythmias ( ventricular tachycardia , ventricular fibrillation , third degree av block or asystole ) during ami ; | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmias",
"pos": [
57,
68
]
} | {
"id": "C0151517",
"name": "third degree av",
"pos": [
124,
139
]
} |
we understand lcmi as a procedure that helps to evaluate the disease stage , to plan therapeutics , to provide a prognosis factor . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
24,
33
]
} | {
"id": "C0220825",
"name": "evaluate",
"pos": [
48,
56
]
} |
total frequency of neoplasms and that of malignant tumors in the younger age group amounted to 78 or 42 % , and in the older age age group to 66 and 31 % respectively , while in the corresponding age groups the figures were as follows : 48 or 7 % ( p less than 0.05 ) . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
19,
28
]
} | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
41,
57
]
} |
it is now clear that complex arrhythmias in the presence of advanced heart disease ( e.g. , myocardial infarction ) signify an increased risk ( two- to fourfold ) . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
44,
47
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
92,
113
]
} |
this supports the notion that both groups present a similar maturational process within the auditory pathways and brainstem , and that arousal is not related to differences in behavioural response to ambient noise during sleep . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioural",
"pos": [
176,
187
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
221,
226
]
} |
among males , however , kaposi 's sarcoma makes up 15 % of all male malignancy and malignant melanoma another 7 % , giving a contrasting picture to developed nations . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
68,
78
]
} | {
"id": "C0025202",
"name": "malignant melanoma",
"pos": [
83,
101
]
} |
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