text
stringlengths
57
1.72k
relation
stringclasses
125 values
h
dict
t
dict
subcapsulary cataracts present a unique feature as in these lenses the cortical water content is enhanced while the fresh lens weight is significantly reduced .
nichd_parent_of
{ "id": "C1521970", "name": "feature", "pos": [ 40, 47 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 127, 133 ] }
the headache may be nonspecific or mimic common nontraumatic headache disorders such as tension , migraine , and cluster .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 4, 12 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 98, 106 ] }
treatable lesions , such as tumour , hydrocephalus , subdural haematoma , porencephaly and hygroma were identified in 22.5 % of cases .
nichd_parent_of
{ "id": "C0027651", "name": "tumour", "pos": [ 28, 34 ] }
{ "id": "C0206620", "name": "hygroma", "pos": [ 91, 98 ] }
rhythms recorded were : ( a ) hemodynamically stable tachyarrhythmias ( supraventricular tachycardia and sustained monomorphic ventricular tachycardia ) -- 21 episodes ;
nichd_parent_of
{ "id": "C0080203", "name": "tachyarrhythmias", "pos": [ 53, 69 ] }
{ "id": "C0039240", "name": "supraventricular tachycardia", "pos": [ 72, 100 ] }
and ( b ) hemodynamically unstable ventricular arrhythmias causing syncope ( hypotensive ventricular tachycardia and ventricular fibrillation ) -- 16 episodes .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 35, 58 ] }
{ "id": "C0042514", "name": "ventricular tachycardia", "pos": [ 89, 112 ] }
and ( b ) hemodynamically unstable ventricular arrhythmias causing syncope ( hypotensive ventricular tachycardia and ventricular fibrillation ) -- 16 episodes .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 35, 58 ] }
{ "id": "C0042510", "name": "ventricular fibrillation", "pos": [ 117, 141 ] }
very few studies have epidemiologically looked at the various types of anxiety and their prevalence in childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 103, 112 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 117, 128 ] }
studies also need to focus on the impact of nonspecific variables such as family communication disorders , dysfunction in both parents , and also the effects of protective variables within individual children and the family .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 189, 199 ] }
{ "id": "C0008059", "name": "children", "pos": [ 200, 208 ] }
a family psychiatry approach to mood disorders brings together genetic and family history studies with epidemiologic patterns of individuals at risk to understand the child 's predicament .
nichd_parent_of
{ "id": "C0027361", "name": "individuals", "pos": [ 129, 140 ] }
{ "id": "C0008059", "name": "child 's", "pos": [ 167, 175 ] }
severity of renal disease varied from microscopic haematuria which has a good prognosis to acute oliguric renal failure which carries a high mortality .
nichd_parent_of
{ "id": "C0022658", "name": "renal disease", "pos": [ 12, 25 ] }
{ "id": "C0022660", "name": "acute", "pos": [ 91, 96 ] }
amiodarone , a newly marketed type iii antiarrhythmic , is indicated in the treatment of life-threatening ventricular dysrhythmias , including sustained ventricular tachycardia and ventricular fibrillation .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular dysrhythmias", "pos": [ 106, 130 ] }
{ "id": "C0042510", "name": "ventricular fibrillation", "pos": [ 181, 205 ] }
a number of studies have indicated that an endogenous brain protein , prp , is associated with transmissible agents causing spongiform encephalopathies such as scrapie , kuru , and creutzfeldt-jakob disease .
nichd_parent_of
{ "id": "C0162534", "name": "spongiform encephalopathies", "pos": [ 124, 151 ] }
{ "id": "C0022336", "name": "creutzfeldt-jakob disease", "pos": [ 181, 206 ] }
in their classificatory system , functional mental disorders would be dichotomized into psychoses and neuroses with the former further divided into schizophrenic , atypical and manic-depressive psychoses , and the latter divided into seven subcategories , i.e. , anxiety neurosis , hysteria , depressive neurosis , phobi...
nichd_parent_of
{ "id": "C0004936", "name": "psychoses", "pos": [ 88, 97 ] }
{ "id": "C0005586", "name": "manic-depressive", "pos": [ 177, 193 ] }
presenting clinical signs significantly associated with adverse outcome ( death or sequelae ) were profound coma , signs of decerebration , absence of corneal reflexes , convulsions at the time of admission and age under three years .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 11, 25 ] }
{ "id": "C0011065", "name": "death", "pos": [ 74, 79 ] }
laboratory findings of prognostic significance were hypoglycaemia , leucocytosis , hyperparasitaemia , elevated plasma concentrations of alanine and 5'-nucleotidase , and elevated plasma or cerebrospinal fluid lactate .
nichd_parent_of
{ "id": "C0587081", "name": "laboratory findings", "pos": [ 0, 19 ] }
{ "id": "C0020615", "name": "hypoglycaemia", "pos": [ 52, 65 ] }
manometry is the most useful method to differentiate hirschsprung 's disease from other conditions , such as extremely short segment aganglionosis , colonic stenosis , and idiopathic megacolon .
nichd_parent_of
{ "id": "C0019569", "name": "hirschsprung 's disease", "pos": [ 53, 76 ] }
{ "id": "C0345237", "name": "short segment aganglionosis", "pos": [ 119, 146 ] }
in 62.5 % of cases ( 25/40 ) tuberculous disease was not recognised in the clinic , the presenting symptomatology was attributed in nearly half the cases to neoplastic disease .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 41, 48 ] }
{ "id": "C0027651", "name": "neoplastic disease", "pos": [ 157, 175 ] }
in order to avoid a diagnostic oversight , sarcoid heart disease should be considered in any patient with unexplained heart block , cardiac arrhythmia , or heart failure .
nichd_parent_of
{ "id": "C0018799", "name": "heart disease", "pos": [ 51, 64 ] }
{ "id": "C0018801", "name": "heart failure", "pos": [ 156, 169 ] }
with increasing doses the rate of occurrence of infectious complications increased in patients given corticosteroids as well as in patients given placebo , a finding suggesting that not only the corticosteroid but also the underlying disease state account for the steroid-associated infectious complications observed in ...
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 158, 165 ] }
{ "id": "C0009566", "name": "complications", "pos": [ 294, 307 ] }
because infections arise from both the endogenous microbial flora and newly acquired organisms and because the pathogens include bacteria , fungi , viruses , and/or parasites and affect a number of different body sites , it has been difficult to conceive of a single or simple method of controlling these multiple infect...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 85, 94 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 111, 120 ] }
because infections arise from both the endogenous microbial flora and newly acquired organisms and because the pathogens include bacteria , fungi , viruses , and/or parasites and affect a number of different body sites , it has been difficult to conceive of a single or simple method of controlling these multiple infect...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 85, 94 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 129, 137 ] }
because infections arise from both the endogenous microbial flora and newly acquired organisms and because the pathogens include bacteria , fungi , viruses , and/or parasites and affect a number of different body sites , it has been difficult to conceive of a single or simple method of controlling these multiple infect...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 85, 94 ] }
{ "id": "C0016832", "name": "fungi", "pos": [ 140, 145 ] }
because infections arise from both the endogenous microbial flora and newly acquired organisms and because the pathogens include bacteria , fungi , viruses , and/or parasites and affect a number of different body sites , it has been difficult to conceive of a single or simple method of controlling these multiple infect...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 85, 94 ] }
{ "id": "C0042776", "name": "viruses", "pos": [ 148, 155 ] }
because infections arise from both the endogenous microbial flora and newly acquired organisms and because the pathogens include bacteria , fungi , viruses , and/or parasites and affect a number of different body sites , it has been difficult to conceive of a single or simple method of controlling these multiple infect...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 85, 94 ] }
{ "id": "C0030498", "name": "parasites", "pos": [ 165, 174 ] }
the emergence of gram-positive organisms as frequent pathogens in neutropenic patients has raised concern regarding empiric gram-positive therapy .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 31, 40 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 53, 62 ] }
the relevance of these general principles to selected examples of cns infections ( i.e. , gram-negative aerobic bacillary meningitis and subacute encephalopathy associated with aids ) is emphasized .
nichd_parent_of
{ "id": "C0007684", "name": "of cns", "pos": [ 63, 69 ] }
{ "id": "C0025289", "name": "meningitis", "pos": [ 122, 132 ] }
if all authors are in agreement on the early symptoms ( leukorrhea , haemorrhages , pelvic pain ) , the lack of diagnosis before the procedure , the lack of information regarding the staging and the grading , as well as the surgical and radiation treatment , there is , above all , controversy regarding the use of chemo...
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 133, 142 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 224, 232 ] }
[ artificial induction of labor at term for medical reasons . comparison of 2 technics for labor induction , oxytocin + early artificial rupture of the membranes versus prostaglandin e2 vaginal gel . open randomized controlled study ] .
nichd_parent_of
{ "id": "C0259787", "name": "labor induction", "pos": [ 91, 106 ] }
{ "id": "C0177273", "name": "artificial rupture of", "pos": [ 126, 147 ] }
it can be concluded that the incidence of specific types of injuries - as exemplified with fractures of any localization and fractures in the rib cage - increases with advancing age .
nichd_parent_of
{ "id": "C0016658", "name": "fractures", "pos": [ 91, 100 ] }
{ "id": "C0035522", "name": "fractures", "pos": [ 125, 134 ] }
six days after the initial presentation of this infection she developed evidence of tropical pyomyositis ( tp ) .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 48, 57 ] }
{ "id": "C0041188", "name": "tropical pyomyositis", "pos": [ 84, 104 ] }
comparison with the basic population reveals statistically significant excessive mortality from gastro-intestinal disease including the subgroups benign ulcer disease and cirrhosis of the liver and accidents including the subgroup of suicide .
nichd_parent_of
{ "id": "C0017178", "name": "gastro-intestinal disease", "pos": [ 96, 121 ] }
{ "id": "C0023890", "name": "cirrhosis of", "pos": [ 171, 183 ] }
[ feasibility and relevance of tumor volumetry for stage classification and assessment of remission of germ cell tumors ] .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 31, 36 ] }
{ "id": "C0205851", "name": "of", "pos": [ 100, 102 ] }
there was no significant difference between the urethra-origin and bladder-origin tccs in the number of tumors that caused clinical signs , metastasized , or that contributed to the death of the dog .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 123, 137 ] }
{ "id": "C0011065", "name": "death", "pos": [ 182, 187 ] }
the results of the cytological and histological examination of 348 canine lesions , localised in various organs , were compared with respect to the tumourous or non-tumour nature of the lesions and the malignancy or benignancy of tumours .
nichd_parent_of
{ "id": "C0027651", "name": "tumour", "pos": [ 148, 154 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 202, 212 ] }
one benign tumor ( fibroleiomyoma ) and two malignant tumors ( transitional cell carcinoma and anaplastic spindle cell sarcoma ) were diagnosed .
nichd_parent_of
{ "id": "C0006826", "name": "malignant tumors", "pos": [ 44, 60 ] }
{ "id": "C0007138", "name": "transitional cell carcinoma", "pos": [ 63, 90 ] }
we present the pathologic changes of the rash , erythema migrans , as well as the neurologic , cardiac , and arthritic changes of the disease .
nichd_parent_of
{ "id": "C0015230", "name": "rash", "pos": [ 41, 45 ] }
{ "id": "C0014740", "name": "erythema migrans", "pos": [ 48, 64 ] }
the paper contains results of investigations on statistical developmental interrelations between the weight of brain , heart , lungs , liver , spleen , kidneys , adrenal glands and thymus , and the total length , the crown-rump length and the body weight , and the circumference of head , shoulders , chest and abdomen o...
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 204, 210 ] }
{ "id": "C0262499", "name": "circumference", "pos": [ 265, 278 ] }
the purpose of this article is to define the place of dermatological autoimmune conditions ( vitiligo , alopecia areata , pemphigus , bullous pemphigoid , dermatitis herpetiformis ) among the mas and to stress the clinical aspects that may aid dermatologists in the care of their patients .
nichd_parent_of
{ "id": "C0037274", "name": "dermatological", "pos": [ 54, 68 ] }
{ "id": "C0042900", "name": "vitiligo", "pos": [ 93, 101 ] }
the purpose of this article is to define the place of dermatological autoimmune conditions ( vitiligo , alopecia areata , pemphigus , bullous pemphigoid , dermatitis herpetiformis ) among the mas and to stress the clinical aspects that may aid dermatologists in the care of their patients .
nichd_parent_of
{ "id": "C0037274", "name": "dermatological", "pos": [ 54, 68 ] }
{ "id": "C0002170", "name": "alopecia areata", "pos": [ 104, 119 ] }
results were less conclusive in patients with meniere 's disease or central neurologic disorders ( multiple sclerosis or heredito-degenerative diseases ) .
nichd_parent_of
{ "id": "C0007682", "name": "central neurologic disorders", "pos": [ 68, 96 ] }
{ "id": "C0026769", "name": "multiple", "pos": [ 99, 107 ] }
the retinal circulation in cases of retinal detachment was studied in eight eyes with rhegmatogenous retinal detachment .
nichd_parent_of
{ "id": "C0035305", "name": "retinal", "pos": [ 4, 11 ] }
{ "id": "C0271055", "name": "rhegmatogenous retinal detachment", "pos": [ 86, 119 ] }
other malignancies that respond to treatment with interferon alfa are malignant melanoma , ovarian carcinoma , and renal cell carcinoma .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 6, 18 ] }
{ "id": "C0025202", "name": "malignant melanoma", "pos": [ 70, 88 ] }
other malignancies that respond to treatment with interferon alfa are malignant melanoma , ovarian carcinoma , and renal cell carcinoma .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 6, 18 ] }
{ "id": "C0007134", "name": "renal cell carcinoma", "pos": [ 115, 135 ] }
more than 50 percent of apnea patients exhibit arterial hypertension , and up to 50 percent of hypertensive patients experience sleep apnea .
nichd_parent_of
{ "id": "C0003578", "name": "apnea", "pos": [ 24, 29 ] }
{ "id": "C0037315", "name": "sleep apnea", "pos": [ 128, 139 ] }
patients with abnormal doppler waveforms had a significantly shorter gestation , infants with lower birth weights , and a higher incidence of adverse pregnancy outcome as determined by meconium , cesarean section for fetal distress , low 1- and 5-minute apgar scores , and days in the neonatal intensive care unit , comp...
nichd_parent_of
{ "id": "C0032972", "name": "of", "pos": [ 139, 141 ] }
{ "id": "C0007876", "name": "cesarean section", "pos": [ 196, 212 ] }
to examine this possibility , and to determine changes with labor , we examined interconversions of prostaglandin e2 to prostaglandin f2 alpha , 13,14-dihydro-15-ketoprostaglandin e2 and 13,14-dihydro-15-ketoprostaglandin f2 alpha by dispersed cells of decidua , chorion , and amnion obtained from patients at term elect...
nichd_parent_of
{ "id": "C0022864", "name": "labor", "pos": [ 60, 65 ] }
{ "id": "C0474461", "name": "spontaneous labor", "pos": [ 350, 367 ] }
the purpose of this study was to assess the accuracy of a quantitative , range-gated , two-dimensional doppler echocardiography method for measurement of blood flow in the fetal lamb descending aorta .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 58, 70 ] }
{ "id": "C1514721", "name": "range", "pos": [ 73, 78 ] }
neither prematurity rate nor weight , length , head circumference , and chest circumference ( considered individually , or as a whole ) showed a significant pattern by type of parental consanguinity .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 38, 44 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 47, 65 ] }
a poor tolerance ( conduction disorders , aggravated arrhythmia ) was noted in 7 patients ( 44 p. cent of the cases ) .
nichd_parent_of
{ "id": "C0264886", "name": "conduction disorders", "pos": [ 19, 39 ] }
{ "id": "C0003811", "name": "arrhythmia", "pos": [ 53, 63 ] }
the model may be useful in defining appropriate populations of organisms for release , methods of release or application , characteristics of a release site that influence containment or dispersal , and in developing an appropriate sampling methodology for monitoring the dispersal of organisms such as genetically engin...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 63, 72 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 326, 334 ] }
proportions were normal in 24 patients with classical congenital adrenal hyperplasia who had received steroid treatment since birth , but one of three patients with non-classical ( late onset ) congenital adrenal hyperplasia had a disproportionately large trunk .
nichd_parent_of
{ "id": "C0001627", "name": "congenital", "pos": [ 54, 64 ] }
{ "id": "C0342467", "name": "late onset", "pos": [ 181, 191 ] }
this method may be useful for statistical purposes as well as for individual care of hearing impaired school children , especially for children who need educational care but can not consult the otological clinics for some reason .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 66, 76 ] }
{ "id": "C0008059", "name": "children", "pos": [ 135, 143 ] }
a new conception of the pathogenesis of cholesteatoma is proposed based on clinical results of anterior tympanotomy , a procedure developed in order to prevent recurrence of cholesteatoma following retraction pocket formation after canal-up operation .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 120, 129 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 241, 250 ] }
some other rare bone tumours and tumorous conditions ( reticulosarcoma , aneurysmal bone cyst , monostotic rib eosinophilic granuloma , osteoid osteoma and lymphangioma ) are also described .
nichd_parent_of
{ "id": "C0027651", "name": "tumorous", "pos": [ 33, 41 ] }
{ "id": "C0024221", "name": "lymphangioma", "pos": [ 156, 168 ] }
a very old population of a rural area of southern italy with a mean age of 87 years was investigated in order to evaluate serum lipid levels and their possible association with health conditions , such as mental status , social behaviour and physical autonomy .
nichd_parent_of
{ "id": "C0220825", "name": "evaluate", "pos": [ 113, 121 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 242, 250 ] }
plasmapheresis can be technically difficult to perform in small children and infants , but should be considered .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 64, 72 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 77, 84 ] }
to study the effect of various valvular heart diseases on the quantitative histology of myocardium , 38 human hearts with valvular lesions were examined ( 11 aortic stenoses , nine mitral stenoses , nine mitral incompetence and nine combined aortic and mitral valve lesions ) .
nichd_parent_of
{ "id": "C0018824", "name": "the", "pos": [ 9, 12 ] }
{ "id": "C0003507", "name": "aortic stenoses", "pos": [ 158, 173 ] }
to study the effect of various valvular heart diseases on the quantitative histology of myocardium , 38 human hearts with valvular lesions were examined ( 11 aortic stenoses , nine mitral stenoses , nine mitral incompetence and nine combined aortic and mitral valve lesions ) .
nichd_parent_of
{ "id": "C0018824", "name": "the", "pos": [ 9, 12 ] }
{ "id": "C0026269", "name": "mitral stenoses", "pos": [ 181, 196 ] }
to study the effect of various valvular heart diseases on the quantitative histology of myocardium , 38 human hearts with valvular lesions were examined ( 11 aortic stenoses , nine mitral stenoses , nine mitral incompetence and nine combined aortic and mitral valve lesions ) .
nichd_parent_of
{ "id": "C0018824", "name": "the", "pos": [ 9, 12 ] }
{ "id": "C0026266", "name": "mitral incompetence", "pos": [ 204, 223 ] }
3 ) no germinomatous components are seen in neonatal teratomas though they are frequently observed in childhood teratomas .
nichd_parent_of
{ "id": "C0039538", "name": "teratomas", "pos": [ 53, 62 ] }
{ "id": "C2347762", "name": "childhood teratomas", "pos": [ 102, 121 ] }
systemic and/or local activation of the ras is seen in many pathological conditions of the cardiovascular system ( e.g . hypertension and congestive heart failure ) .
nichd_parent_of
{ "id": "C0007222", "name": "conditions of the cardiovascular system", "pos": [ 73, 112 ] }
{ "id": "C0020538", "name": "hypertension", "pos": [ 121, 133 ] }
high serum interleukin-2 levels in acute myeloid leukaemia ( aml ) are associated with fab m4 and m5 subtypes .
nichd_parent_of
{ "id": "C0023467", "name": "acute myeloid leukaemia", "pos": [ 35, 58 ] }
{ "id": "C0023479", "name": "fab m4", "pos": [ 87, 93 ] }
a correlation analysis between bmr and other biological and physical characteristics revealed bodyweight and gestation as the only variables related to bmr and oxygen consumption .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 69, 84 ] }
{ "id": "C0005910", "name": "bodyweight", "pos": [ 94, 104 ] }
341 incident cases of stroke , 253 of acute myocardial infarction , 220 of ischaemic heart disease , and 317 of other heart disease were reported among respondents without a reported history of angina , myocardial infarction , or stroke .
nichd_parent_of
{ "id": "C0018799", "name": "of", "pos": [ 19, 21 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 203, 224 ] }
the etiologies of cardiac disease leading to transplantation in this series were : cardiomyopathy in 19/31 patients ( 61 % ) , ischemic heart disease in 7/31 ( 23 % ) , valvular disease in 2/31 ( 6 % ) , life threatening arrythmias in 2/31 ( 6 % ) and primary cardiac tumor in 1/31 ( 3 % ) .
nichd_parent_of
{ "id": "C0018799", "name": "the", "pos": [ 0, 3 ] }
{ "id": "C0878544", "name": "cardiomyopathy", "pos": [ 83, 97 ] }
in order to ascertain the value of this investigation in penetrating abdominal trauma , we conducted a prospective study , over a 4-month period , involving 35 patients with stab wounds to the abdomen whose initial clinical examination was equivocal .
nichd_parent_of
{ "id": "C0220825", "name": "investigation", "pos": [ 40, 53 ] }
{ "id": "C0031809", "name": "clinical examination", "pos": [ 215, 235 ] }
since both aerobic and anaerobic organisms may be involved in wound infections , and because antibiotic sensitivity of many of these pathogens is unpredictable , broad-spectrum antimicrobial therapy is often warranted initially .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 33, 42 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 133, 142 ] }
surgical resections were performed ( lobectomy for the brain abscess , partial resection for the renal abscess followed , after extension of the infection , by right nephrectomy ) combined with therapy with itraconazole , a new antimycotic agent .
nichd_parent_of
{ "id": "C0000833", "name": "abscess", "pos": [ 61, 68 ] }
{ "id": "C0151465", "name": "renal abscess", "pos": [ 97, 110 ] }
the type ii collagen induced arthritis animal model ( cia ) provides opportunities to study the nature of autoimmune reactions leading to arthritis and is also a useful model for rheumatoid arthritis ( ra ) .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 29, 38 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 179, 199 ] }
the database , maintained at the university of minnesota 's nutrition coordinating center ( ncc ) , has been used to calculate dietary intake data for a wide range of diet-disease related investigations including studies on cardiovascular disease , hypertension , cancer , gastroenterology , and osteoporosis .
nichd_parent_of
{ "id": "C0007222", "name": "cardiovascular disease", "pos": [ 224, 246 ] }
{ "id": "C0020538", "name": "hypertension", "pos": [ 249, 261 ] }
tass was designed to address the use of the drug in the prevention of stroke in patients who had been diagnosed as having had one or more transient ischemic attacks ( tias ) , using aspirin as a positive control .
nichd_parent_of
{ "id": "C0038454", "name": "tass", "pos": [ 0, 4 ] }
{ "id": "C0007787", "name": "transient ischemic attacks", "pos": [ 138, 164 ] }
a total of 344 specimens were negative for any organisms while a further 140 were only positive for parasites which have been implicated as being pathogenic , including ascaris lumbricoides , hymenolepis nana , trichomonas hominis and blastocysts hominis were considered to be at least potentially pathogenic and capable...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 47, 56 ] }
{ "id": "C0030498", "name": "parasites", "pos": [ 100, 109 ] }
a total of 344 specimens were negative for any organisms while a further 140 were only positive for parasites which have been implicated as being pathogenic , including ascaris lumbricoides , hymenolepis nana , trichomonas hominis and blastocysts hominis were considered to be at least potentially pathogenic and capable...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 47, 56 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 298, 308 ] }
greater sensitivity was achieved using fluid-phase antibody ( as culture supernatants ) in the assay than was obtained with pre-sensitized red cells .
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 39, 44 ] }
{ "id": "C0003241", "name": "antibody", "pos": [ 51, 59 ] }
on individual occasions it was possible to show a significant association of the presence of lt-etec between the fingerprints of children and their stools , fingerprints of mothers and children , and weaning food and the stools of the child consuming the food .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 3, 13 ] }
{ "id": "C0008059", "name": "child", "pos": [ 235, 240 ] }
the study shows that p. aeruginosa-infected cf patients may harbour the organisms also in the intestinal tract , and may spread the bacteria into toilets .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 72, 81 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 132, 140 ] }
the distribution and frequency of aphidicolin-induced common fragile sites were studied in epstein-barr virus-transformed b lymphocytes from eight normal individuals , and in bone marrow cells from six children in remission from malignant blood diseases .
nichd_parent_of
{ "id": "C0027361", "name": "individuals", "pos": [ 154, 165 ] }
{ "id": "C0008059", "name": "children", "pos": [ 202, 210 ] }
as it is not possible to base malaria vaccines on the use of killed or attenuated organisms , the vaccines which are being developed are subunit vaccines in which the immunogens consist of defined parasite antigens or antigenic fragments .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 82, 91 ] }
{ "id": "C0030498", "name": "parasite", "pos": [ 197, 205 ] }
hepatitis b surface antigen ( hbsag ) induced an immune complex-type hypersensitivity which developed at 5-6 hr after the challenge and could be transferred by anti-hbs antisera , in addition to the delayed-type hypersensitivity in b10.br mice .
nichd_parent_of
{ "id": "C0020517", "name": "hypersensitivity", "pos": [ 69, 85 ] }
{ "id": "C0020522", "name": "delayed-type", "pos": [ 199, 211 ] }
our results indicate that local combined treatments with il-1 and il-2 can induce potent , host-dependent ( t cell-mediated ) anti-tumor effects against highly malignant tumors .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 131, 136 ] }
{ "id": "C0006826", "name": "malignant", "pos": [ 160, 169 ] }
in order to determine whether a deregulation in the rap transcription levels could be involved per se in the multistep carcinogenic process , we chose to analyze tumors for which the ras mutation rate was previously reported to be extremely rare or unknown , i.e. , non-hodgkin 's lymphomas , certain types of carcinoma ...
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 162, 168 ] }
{ "id": "C0027766", "name": "tumors of the nervous system", "pos": [ 378, 406 ] }
this density has a median of about three cancers per 100 gy and has a 95 % probability interval from 0.8 to 11 bone cancers per 100 gy .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 41, 48 ] }
{ "id": "C0279530", "name": "bone cancers", "pos": [ 111, 123 ] }
the severity of the urinary tract infection ( risk of renal scars ) is best correlated with its estimated degree of tissue penetration clinically ( fever , general condition ) and on laboratory tests ( sedimentation rate , c-reactive protein ) .
nichd_parent_of
{ "id": "C0022885", "name": "laboratory tests", "pos": [ 183, 199 ] }
{ "id": "C1176468", "name": "sedimentation rate", "pos": [ 202, 220 ] }
beta-lactamase activity was usually present in the sputum sol phase and originated from organisms not usually considered to be the major pathogen .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 88, 97 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 137, 145 ] }
the hip study had 25 per cent fewer breast cancer deaths at 18 years in women under age 50 at the start of the trial , but because only 12 patients under age 50 had mammographically detectable tumors ( out of 89 cancers diagnosed in the screened group ) , most of the benefit must be due to physical examinations or incr...
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 193, 199 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 212, 219 ] }
by means of the superselective pulmonary arteriography , vascular wall irregularities and tumor stain were frequently observed in the cases of malignancies .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 90, 95 ] }
{ "id": "C0006826", "name": "malignancies", "pos": [ 143, 155 ] }
to provide a more detailed assessment of the growth of twins , the individual second trimester growth patterns of six fetal parameters [ hc , ac , fdl , thc , head cube ( a ) and abdominal cube ( b ) ] were studied in fourteen sets of normal twins ( six monozygotic and eight dizygotic ) and sixteen normal singletons us...
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 67, 77 ] }
{ "id": "C0015965", "name": "fetal", "pos": [ 118, 123 ] }
in 40 febrile neutropenic episodes during the induction and consolidation chemotherapy of acute leukaemia in riyadh , 51 % of organisms causing septicaemia were gram-negative , 26 % gram-positive , 8 % anaerobes and 15 % fungi .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 126, 135 ] }
{ "id": "C0016832", "name": "fungi", "pos": [ 221, 226 ] }
this article discusses the behavior , nursing management , family education and pharmacologic interventions for the patient exhibiting agitated and aggressive behavior .
nichd_parent_of
{ "id": "C0004927", "name": "behavior", "pos": [ 27, 35 ] }
{ "id": "C0006147", "name": "nursing", "pos": [ 38, 45 ] }
this article contains a brief discussion of the various modalities of aneurysm wrapping in its early years , product options available today , characteristics and manifestations of intracranial aneurysms and a synopsis of the surgical procedure .
nichd_parent_of
{ "id": "C0002940", "name": "aneurysm", "pos": [ 70, 78 ] }
{ "id": "C0007766", "name": "intracranial aneurysms", "pos": [ 181, 203 ] }
the tam provided information giving clues to the prosodic features of rhythm and length of sounds .
nichd_parent_of
{ "id": "C1521970", "name": "features", "pos": [ 58, 66 ] }
{ "id": "C1444754", "name": "length", "pos": [ 81, 87 ] }
the persistently infected ( p.i . ) cultures were characterized by the following properties : virus infection was limited to a minority of cells , small amounts of infectious virus were produced together with low levels of interferon ( ifn ) and the cultures were resistant to superinfection by homologous virus and vesi...
nichd_parent_of
{ "id": "C0042769", "name": "infectious virus", "pos": [ 164, 180 ] }
{ "id": "C0021400", "name": "influenza", "pos": [ 356, 365 ] }
a primary goal was to develop procedures and methods to evaluate the emissions of organic mutagens resulting from incomplete combustion of municipal waste .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 30, 40 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 56, 64 ] }
his clinical findings are reported in this article along with a brief history and discussion of the diagnosis and prevention of legionnaire 's disease .
nichd_parent_of
{ "id": "C0037088", "name": "clinical", "pos": [ 4, 12 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 100, 109 ] }
drugs that lower pressure will prevent heart failure and arteriolar complications such as renal failure or strokes caused by lacunar infarction or brain haemorrhage due to rupture of microaneurysms .
nichd_parent_of
{ "id": "C0038454", "name": "strokes", "pos": [ 107, 114 ] }
{ "id": "C0553692", "name": "brain haemorrhage", "pos": [ 147, 164 ] }
clinical recognition and differentiation of these disorders along with appropriate use of objective , noninvasive isotopic and venographic studies should lead to accurate diagnosis and management of these venous syndromes .
nichd_parent_of
{ "id": "C0012634", "name": "disorders", "pos": [ 50, 59 ] }
{ "id": "C0039082", "name": "syndromes", "pos": [ 212, 221 ] }
herpes simplex virus type-1 ( hsv-1 ) was identified by immunological staining using virus-specific monoclonal antibodies in the epithelial cells of such ulcers from two patients with malignant lymphoma ( ml ) , three with acute myeloblastic leukemia ( aml ) , one with refractomy anemia with excess blasts , two with ch...
nichd_parent_of
{ "id": "C0002871", "name": "anemia", "pos": [ 281, 287 ] }
{ "id": "C0002874", "name": "aplastic anemia", "pos": [ 415, 430 ] }
previous failure to identify these organisms may reflect their poor growth on agar not supplemented with lipid and their resemblance to bacteria considered to be commensals and non-pathogenic .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 35, 44 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 136, 144 ] }
previous failure to identify these organisms may reflect their poor growth on agar not supplemented with lipid and their resemblance to bacteria considered to be commensals and non-pathogenic .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 35, 44 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 181, 191 ] }
disorders of electrolytes such as hypokalemia and hyponatremia were seen in 45.5 % of the aged .
nichd_parent_of
{ "id": "C1704431", "name": "disorders of electrolytes", "pos": [ 0, 25 ] }
{ "id": "C0020621", "name": "hypokalemia", "pos": [ 34, 45 ] }