text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
As this case report shows , drug-induced immune thrombocytopenia may present another possible mechanism for bleeding in SSRI-treated patients . | {
"id": "C0019080",
"pos": [
108,
116
],
"name": "bleeding"
} | {
"id": "C0272290",
"pos": [
28,
64
],
"name": "drug-induced immune thrombocytopenia"
} | 0NA |
Biofouling of membranes caused by the bacterial load in water reduces the quality of drinking water and has become a major problem . | {
"id": "C0033213",
"pos": [
123,
130
],
"name": "problem"
} | {
"id": "C0043047",
"pos": [
56,
61
],
"name": "water"
} | 0NA |
We found that bone conduction ultrasound irradiation at 50 kHz and 83 kHz on the guinea pig inner ear for six hours leads to hair cell damage . | {
"id": "C0010957",
"pos": [
135,
141
],
"name": "damage"
} | {
"id": "C0022889",
"pos": [
92,
101
],
"name": "inner ear"
} | 0NA |
However , the P216 G mutant was severely compromised in folding into a catalytically competent enzyme . | {
"id": "C0205082",
"pos": [
32,
40
],
"name": "severely"
} | {
"id": "C0185026",
"pos": [
56,
63
],
"name": "folding"
} | 0NA |
The most common mode of injury was grinding ( 88 % ) . | {
"id": "C3263722",
"pos": [
24,
30
],
"name": "injury"
} | {
"id": "C0185051",
"pos": [
35,
43
],
"name": "grinding"
} | 0NA |
A high index of suspicion is warranted in any patient presenting with hemoptysis and a recent past history of subacute bacterial endocarditis , intravascular interventions , known aortic aneurysm , and/or immunocompromised state . | {
"id": "C0014121",
"pos": [
119,
141
],
"name": "bacterial endocarditis"
} | {
"id": "C0003486",
"pos": [
180,
195
],
"name": "aortic aneurysm"
} | 0NA |
At the time of first-episode psychosis presentation , it is crucial that clinicians select the most effective treatment option as immediate intervention offers the best chance for containing the illness . | {
"id": "C0221423",
"pos": [
195,
202
],
"name": "illness"
} | {
"id": "C0184661",
"pos": [
140,
152
],
"name": "intervention"
} | 0NA |
As a possible underlying physiological mechanism , we identified the movement of the ventricular muscle band which possibly sealed the perforation side due to transverse and circumferential muscle contractions . | {
"id": "C1140999",
"pos": [
197,
209
],
"name": "contractions"
} | {
"id": "C0026649",
"pos": [
69,
77
],
"name": "movement"
} | 0NA |
Rats were sacrificed 24h after the last session of exercise portion of the liver was excised , immediately washed in ice-cold saline , and frozen in liquid nitrogen for extraction of ABCA1 mRNA . | {
"id": "C0023884",
"pos": [
75,
80
],
"name": "liver"
} | {
"id": "C0185115",
"pos": [
169,
179
],
"name": "extraction"
} | 0NA |
Serum etoposide levels were obtained at 2 and 4 hours after infusion . | {
"id": "C0015133",
"pos": [
6,
15
],
"name": "etoposide"
} | {
"id": "C0574032",
"pos": [
60,
68
],
"name": "infusion"
} | 0NA |
In this case report , we describe an adult patient with end-stage renal disease in whom the hepatic vein was the only available access to implant a single-lead permanent cardiac pacemaker . | {
"id": "C0019155",
"pos": [
92,
104
],
"name": "hepatic vein"
} | {
"id": "C0021102",
"pos": [
138,
145
],
"name": "implant"
} | 0NA |
These included splenomegaly , lymphadenopathy , hepatomegaly , multifocal hepatitis , anemia , altered trafficking of B cells and CD8 T cells , loss of NK cells , and a 10-fold increase in bone marrow ( BM ) cells bearing the phenotype of hemopoietic stem cells . | {
"id": "C0005953",
"pos": [
189,
200
],
"name": "bone marrow"
} | {
"id": "C0497156",
"pos": [
30,
45
],
"name": "lymphadenopathy"
} | 0NA |
Eighteen patients who underwent resection of oral cavity squamous cell carcinoma were reviewed . | {
"id": "C0015252",
"pos": [
32,
41
],
"name": "resection"
} | {
"id": "C0007137",
"pos": [
57,
80
],
"name": "squamous cell carcinoma"
} | 0NA |
When in the third or fourth position , nanofibers are formed exclusively above 10 μM. We propose that moving the Isoleucine away from the tail enhances its ability to promote β-sheet formation instead of folding back into the palmitoyl core . | {
"id": "C0185026",
"pos": [
204,
211
],
"name": "folding"
} | {
"id": "C0022192",
"pos": [
113,
123
],
"name": "Isoleucine"
} | 0NA |
The mean presenting visual acuity in the better eye was 0.76 + /- 0.53 logMAR ( logarithm of the minimum angle of resolution ) units . | {
"id": "C0015392",
"pos": [
48,
51
],
"name": "eye"
} | {
"id": "C0042812",
"pos": [
20,
33
],
"name": "visual acuity"
} | 0NA |
A diet drawn up according to the proposed guidelines could decrease the incidence of breast , colon-rectal , prostate and bronchogenic cancer . | {
"id": "C0006141",
"pos": [
85,
91
],
"name": "breast"
} | {
"id": "C0033572",
"pos": [
109,
117
],
"name": "prostate"
} | 0NA |
Hemonectin ( HN ) is a bone marrow ( BM ) protein that promotes specific attachment of immature granulocytes and their precursors within the BM . | {
"id": "C0185023",
"pos": [
73,
83
],
"name": "attachment"
} | {
"id": "C0005953",
"pos": [
23,
34
],
"name": "bone marrow"
} | 0NA |
Free flap reconstruction of head and neck defects is a rapidly changing field . | {
"id": "C0018670",
"pos": [
28,
32
],
"name": "head"
} | {
"id": "C0027530",
"pos": [
37,
41
],
"name": "neck"
} | 0NA |
Although the nervous system is not considered a primary target of the underlying molecular defect , recently , increasing attention has been focused on neurological manifestations of EDS . | {
"id": "C0027763",
"pos": [
13,
27
],
"name": "nervous system"
} | {
"id": "C0013720",
"pos": [
183,
186
],
"name": "EDS"
} | 0NA |
The infection also plays an important role in the initiation and/or progression of gastric atrophy and intestinal metaplasia , which may eventually lead to the development of distal gastric cancer . | {
"id": "C0017154",
"pos": [
83,
98
],
"name": "gastric atrophy"
} | {
"id": "C0009450",
"pos": [
4,
13
],
"name": "infection"
} | 0NA |
After achievement of a partial remission ( FVIII activity 28 % ) by combined immunosuppressive therapy ( prednisone , cyclophosphamide , plasmapheresis and immunoadsorption ) , subsequently , two relapses occurred following steroid tapering . | {
"id": "C0038317",
"pos": [
224,
231
],
"name": "steroid"
} | {
"id": "C0010583",
"pos": [
118,
134
],
"name": "cyclophosphamide"
} | 0NA |
The study subjects were 152 patients with gastric cancer who underwent distal gastrectomy with lymphadenectomy between 2002 and 2007 . | {
"id": "C0024203",
"pos": [
95,
110
],
"name": "lymphadenectomy"
} | {
"id": "C0192440",
"pos": [
71,
89
],
"name": "distal gastrectomy"
} | 0NA |
Bivariate models showed a significant association of malaria risk with elevation , annual maximum temperature , rainfall and potential evapotranspiration ( PET ) . | {
"id": "C0024530",
"pos": [
53,
60
],
"name": "malaria"
} | {
"id": "C0005903",
"pos": [
98,
109
],
"name": "temperature"
} | 15interprets |
Third ventricle leptin infusion inhibited food intake and caused weight loss . | {
"id": "C0574032",
"pos": [
23,
31
],
"name": "infusion"
} | {
"id": "C0013470",
"pos": [
42,
53
],
"name": "food intake"
} | 0NA |
Patients with chronic respiratory failure , especially COPD , suffer from a multi-systemic disease with organic , behavioral and social consequences that impact largely beyond the respiratory system . | {
"id": "C0035237",
"pos": [
180,
198
],
"name": "respiratory system"
} | {
"id": "C0264492",
"pos": [
14,
41
],
"name": "chronic respiratory failure"
} | 11finding_site_of |
Among prisoners screening positive on the AUDIT , expectations of post-release drinking and ATS use are potential targets for intervention to reduce future hazardous drinking . | {
"id": "C0184661",
"pos": [
126,
138
],
"name": "intervention"
} | {
"id": "C0199230",
"pos": [
16,
25
],
"name": "screening"
} | 0NA |
Bladder volume and bladder wall thickness were log-transformed to achieve approximate normality and homogeneity of variance . | {
"id": "C0005682",
"pos": [
0,
7
],
"name": "Bladder"
} | {
"id": "C0458421",
"pos": [
19,
31
],
"name": "bladder wall"
} | 0NA |
Overnight electroencephalogram was recorded while participants were presented with tones during stage 2 NREM sleep to elicit KCs . | {
"id": "C0022575",
"pos": [
125,
128
],
"name": "KCs"
} | {
"id": "C0013819",
"pos": [
10,
30
],
"name": "electroencephalogram"
} | 0NA |
This study supports the findings that continent women with significant sphincter defects on ultrasound evaluation may be considered for restorative proctocolectomy . | {
"id": "C0041618",
"pos": [
92,
102
],
"name": "ultrasound"
} | {
"id": "C0429956",
"pos": [
38,
47
],
"name": "continent"
} | 0NA |
Most pediatric pituitary adenomas present after the onset of puberty and present with frequent headaches , changes in visual acuity and , in females , menstrual dysfunction . | {
"id": "C0032000",
"pos": [
15,
33
],
"name": "pituitary adenomas"
} | {
"id": "C0042812",
"pos": [
118,
131
],
"name": "visual acuity"
} | 0NA |
Pre-clinical studies suggest mitigating effect of dietary flavonoid quercetin against cancer and other diseases . | {
"id": "C0006826",
"pos": [
86,
92
],
"name": "cancer"
} | {
"id": "C0012634",
"pos": [
103,
111
],
"name": "diseases"
} | 0NA |
Serum troponins are sensitive markers used to diagnose acute coronary syndrome in association with signs and symptoms of chest pain and EKG changes . | {
"id": "C0020517",
"pos": [
20,
29
],
"name": "sensitive"
} | {
"id": "C0008031",
"pos": [
121,
131
],
"name": "chest pain"
} | 0NA |
APS treatment reduced cell accumulation , swelling and arthritic index of the joints and serum concentrations of TNF-α and IL1-β in a dose-dependent manner in AA rats . | {
"id": "C0022417",
"pos": [
78,
84
],
"name": "joints"
} | {
"id": "C0013604",
"pos": [
42,
50
],
"name": "swelling"
} | 0NA |
Group II underwent computer-controlled bipolar electrosurgery ; vascular and mesocolon section was completed by using the 10-mm Ligasure device alone . | {
"id": "C0005847",
"pos": [
64,
72
],
"name": "vascular"
} | {
"id": "C0025483",
"pos": [
77,
86
],
"name": "mesocolon"
} | 0NA |
The combined use of the three assay systems classified 258 ( 25.4 % ) , 278 ( 27.4 % ) , and 263 ( 25.9 % ) of 1015 strains tested as positive for SEA , SEB , and SEC , respectively . | {
"id": "C1446409",
"pos": [
134,
142
],
"name": "positive"
} | {
"id": "C0080194",
"pos": [
116,
123
],
"name": "strains"
} | 0NA |
To test the robustness of the model a Rank Order Stability Assessment was performed that showed that even if fluoxetine and/or amitriptyline were given away free , a scenario starting with venlafaxine would still be the least costly treatment over a 6-month period . | {
"id": "C0016365",
"pos": [
109,
119
],
"name": "fluoxetine"
} | {
"id": "C0025344",
"pos": [
258,
264
],
"name": "period"
} | 0NA |
Input impedance of a rigid-wall polyethylene tube ( Zt ) was measured when the tube was filled with various mixtures of carrier gases ( air , 100 % oxygen , 50 % oxygen+50 % nitrogen ) to which different concentrations of volatile anaesthetic inhalation agents ( halothane , isoflurane , sevoflurane , and desflurane ) had been added . | {
"id": "C0063252",
"pos": [
306,
316
],
"name": "desflurane"
} | {
"id": "C0175730",
"pos": [
79,
83
],
"name": "tube"
} | 0NA |
Minimal incision approach to osteotomy of the hallux results in less trauma and eliminates the need for internal fixation . | {
"id": "C0029468",
"pos": [
29,
38
],
"name": "osteotomy"
} | {
"id": "C0016642",
"pos": [
104,
121
],
"name": "internal fixation"
} | 0NA |
Although there have been significant advancements in device technologies , anticoagulation protocols , and multidisciplinary team management , bleeding and thrombosis are the most common adverse effects . | {
"id": "C0019080",
"pos": [
143,
151
],
"name": "bleeding"
} | {
"id": "C0040053",
"pos": [
156,
166
],
"name": "thrombosis"
} | 0NA |
The lower epithelium was significantly more responsive to aromatic amino acids ( L-tryptophan , L-tyrosine , L-DOPA , and L-phenylalanine ) , L-leucine , and L-asparagine than the upper . | {
"id": "C0023570",
"pos": [
109,
115
],
"name": "L-DOPA"
} | {
"id": "C0041485",
"pos": [
96,
106
],
"name": "L-tyrosine"
} | 0NA |
Diagnostic laparoscopy confirmed a thickened terminal ileum causing small bowel obstruction . | {
"id": "C0020885",
"pos": [
54,
59
],
"name": "ileum"
} | {
"id": "C0031150",
"pos": [
0,
22
],
"name": "Diagnostic laparoscopy"
} | 0NA |
During machine perfusion lactates decreased , vascular flow was stable , and bile production restored , and the graft was considered suitable for transplantation . | {
"id": "C0005388",
"pos": [
77,
81
],
"name": "bile"
} | {
"id": "C0040732",
"pos": [
146,
161
],
"name": "transplantation"
} | 0NA |
This provisional report on 101 postpartum patients indicates that Filshie clip application to the fallopian tubes is a satisfactory method for postpartum sterilization . | {
"id": "C0015560",
"pos": [
98,
113
],
"name": "fallopian tubes"
} | {
"id": "C0185125",
"pos": [
79,
90
],
"name": "application"
} | 0NA |
For instance , styrylbenzoazole derivative BF-227 , currently used as an amyloid imaging probe of positron emission tomography in Alzheimer disease , is useful also for the diagnosis of Gerstmann-Sträussler-Scheinker syndrome . | {
"id": "C0002395",
"pos": [
130,
147
],
"name": "Alzheimer disease"
} | {
"id": "C0017495",
"pos": [
186,
225
],
"name": "Gerstmann-Sträussler-Scheinker syndrome"
} | 0NA |
Cordycepin exhibits various bio-activities , including anticancer , antibacterial , antiviral and immune regulation activities , and is a significant focus of research . | {
"id": "C0003451",
"pos": [
84,
93
],
"name": "antiviral"
} | {
"id": "C0056331",
"pos": [
0,
10
],
"name": "Cordycepin"
} | 0NA |
This rare disease is often only discovered incidentally as a consequence of mechanical complications and not well reported in the international literature , compared to intussusception due to an isolated lipoma . | {
"id": "C0023798",
"pos": [
204,
210
],
"name": "lipoma"
} | {
"id": "C0012634",
"pos": [
10,
17
],
"name": "disease"
} | 0NA |
1 . After a resting period of up to 6 months cells of Nitrobacter agilis grow with acetate , formate , and pyruvate as carbon and energy source . | {
"id": "C0000975",
"pos": [
83,
90
],
"name": "acetate"
} | {
"id": "C0007009",
"pos": [
119,
125
],
"name": "carbon"
} | 0NA |
Congenital midline cervical cleft is a rare anomaly that typically presents in the neonatal period as a thin suprasternal vertical band of erythematous skin with a nipple-like projection superiorly , which may exude fluid . | {
"id": "C0332447",
"pos": [
44,
51
],
"name": "anomaly"
} | {
"id": "C0444099",
"pos": [
152,
156
],
"name": "skin"
} | 0NA |
Each site provided either the comprehensive postacute stroke intervention or standard care according to the randomisation assignment . | {
"id": "C0184661",
"pos": [
61,
73
],
"name": "intervention"
} | {
"id": "C0038454",
"pos": [
54,
60
],
"name": "stroke"
} | 0NA |
Females ( adjPRR = 1.47 , 95 % CI 1.38 - 1.56 ) , non-Hispanic blacks ( adjPRR = 2.03 , 95 % CI 1.82 - 2.27 ) , single ( adjPRR = 1.15 , 95 % CI 1.07 - 1.25 ) , divorced ( adjPRR = 1.28 , 95 % CI 1.15 - 1.41 ) , and unemployed patients ( adjPRR = 1.13 , 95 % CI 1.05 - 1.21 ) had significantly higher rates of HSV-2 infection . | {
"id": "C0041674",
"pos": [
232,
242
],
"name": "unemployed"
} | {
"id": "C0009450",
"pos": [
336,
345
],
"name": "infection"
} | 0NA |
Patients who underwent delayed reconstruction reported higher scores on satisfaction with breasts , outcome , and nipples . | {
"id": "C0006141",
"pos": [
90,
97
],
"name": "breasts"
} | {
"id": "C0028109",
"pos": [
114,
121
],
"name": "nipples"
} | 0NA |
In some patients with breast cancer , hypercalcemia results from treatment with estrogens , antiestrogens , androgens , or progestins . | {
"id": "C0014939",
"pos": [
80,
89
],
"name": "estrogens"
} | {
"id": "C0033306",
"pos": [
123,
133
],
"name": "progestins"
} | 0NA |
Terfenadine and astemizole , two antihistamines of the second generation , are in vitro potent blockers of potassium channels ( K+ ) . | {
"id": "C0019590",
"pos": [
33,
47
],
"name": "antihistamines"
} | {
"id": "C0085173",
"pos": [
0,
11
],
"name": "Terfenadine"
} | 0NA |
Interestingly , cetuximab , a drug used in treatment of certain cancers , acts an inhibitor of the EGF receptor and causes hypomagnesemia which may be due to the inhibition of EGF signaling . | {
"id": "C0013227",
"pos": [
30,
34
],
"name": "drug"
} | {
"id": "C0006826",
"pos": [
64,
71
],
"name": "cancers"
} | 0NA |
Based on these findings and those of the literature , it is suggested that cases of systemic listeriosis be treated with a combination of a beta-lactam antibiotic , preferably ampicillin , with an appropriate aminoglycoside , such as gentamicin . | {
"id": "C0026458",
"pos": [
140,
162
],
"name": "beta-lactam antibiotic"
} | {
"id": "C0002680",
"pos": [
176,
186
],
"name": "ampicillin"
} | 0NA |
After stimulation with insulin or IGF-I , bovine fibroblasts ( 3 X 10(5 ) cells ) secreted approximately 30 ng/24 h 42,000/38,000 Mr IGFBP . | {
"id": "C1292856",
"pos": [
6,
17
],
"name": "stimulation"
} | {
"id": "C0021641",
"pos": [
23,
30
],
"name": "insulin"
} | 0NA |
A 75-year-old woman with dementia presented with per rectal bleeding , rectal prolapse and lower abdominal pain . | {
"id": "C0011265",
"pos": [
25,
33
],
"name": "dementia"
} | {
"id": "C0018932",
"pos": [
53,
68
],
"name": "rectal bleeding"
} | 0NA |
Some of the compounds investigated here showed effective hCA inhibitory activity , and might be used as leads for generating novel carbonic anhydrase inhibitors which are valuable drug candidates for the treatment of glaucoma , epilepsy , gastric and duodenal ulcers , neurological disorders , and osteoporosis . | {
"id": "C0029456",
"pos": [
298,
310
],
"name": "osteoporosis"
} | {
"id": "C0017601",
"pos": [
217,
225
],
"name": "glaucoma"
} | 0NA |
The anti-fibrotic effects were possibly through the stimulation of MMP-13 from myofibroblasts , and the enhanced accumulation of non-myofibroblastic BM cells and macrophages in the pancreas . | {
"id": "C0030274",
"pos": [
181,
189
],
"name": "pancreas"
} | {
"id": "C1292856",
"pos": [
52,
63
],
"name": "stimulation"
} | 0NA |
The most common mechanism of injury for this area of the knee involves a combined hyperextension and varus force that is frequently of high energy . | {
"id": "C3263722",
"pos": [
29,
35
],
"name": "injury"
} | {
"id": "C0231451",
"pos": [
82,
96
],
"name": "hyperextension"
} | 0NA |
We started follow-up 1-year after ulcer diagnosis to avoid detection bias and calculated absolute risks of cancer and standardized incidence ratios ( SIRs ) . | {
"id": "C0041582",
"pos": [
34,
39
],
"name": "ulcer"
} | {
"id": "C0006826",
"pos": [
107,
113
],
"name": "cancer"
} | 0NA |
Atypical antipsychotic agents included aripiprazole , clozapine , olanzapine , quetiapine , risperidone , and ziprasidone . | {
"id": "C0171023",
"pos": [
66,
76
],
"name": "olanzapine"
} | {
"id": "C0123091",
"pos": [
79,
89
],
"name": "quetiapine"
} | 0NA |
Coagulation was minimally activated during the passage of blood from the vein to the chamber as shown by fibrinopeptide A levels of 3.7 ng/ml after 5-minute perfusions . | {
"id": "C0005767",
"pos": [
58,
63
],
"name": "blood"
} | {
"id": "C0042449",
"pos": [
73,
77
],
"name": "vein"
} | 0NA |
Among biological methods for As-contaminated water treatment , microbial As(III)-oxidation is one of the most promising approaches since it can be coupled to commonly used adsorption removal technologies , without requiring the addition of chemicals and producing toxic by-products . | {
"id": "C0015252",
"pos": [
183,
190
],
"name": "removal"
} | {
"id": "C0220806",
"pos": [
240,
249
],
"name": "chemicals"
} | 0NA |
This result was confirmed by field trapping ; removal of (Z , E)-9,12-tetradecadienal from quaternary blends completely suppressed the male catches . | {
"id": "C0015252",
"pos": [
46,
53
],
"name": "removal"
} | {
"id": "C0596011",
"pos": [
140,
147
],
"name": "catches"
} | 0NA |
Acute E2 treatment resulted in increased CRE-DNA binding in the frontal cortex but not in amygdala , hippocampus , or cerebellum . | {
"id": "C0007765",
"pos": [
118,
128
],
"name": "cerebellum"
} | {
"id": "C0016733",
"pos": [
64,
78
],
"name": "frontal cortex"
} | 0NA |
A well-trained transplant team must carry out the potential donor , the liver grafts manipulation and the graft receptor , in the condition of a competitive medical system . | {
"id": "C0040732",
"pos": [
15,
25
],
"name": "transplant"
} | {
"id": "C0012634",
"pos": [
130,
139
],
"name": "condition"
} | 0NA |
In univariate analysis the prognostic factors identified for local progression-free survival were histology ( p = 0.008 ) , FIGO stage ( p < 0.001 ) , initial hemoglobin ( Hgb ) level ( p = 0.001 ) , total radiation dose ( p = 0.039 ) , use of brachytherapy ( p = 0.001 ) and of chemotherapy ( p = 0.037 ) and enlarged paraaortic nodes ( p = 0.016 ) . | {
"id": "C0006098",
"pos": [
244,
257
],
"name": "brachytherapy"
} | {
"id": "C0013216",
"pos": [
279,
291
],
"name": "chemotherapy"
} | 0NA |
Our results are promising regarding the distinction between tumour and healthy surrounding tissue , and indicate that presurgical mapping of basal cell carcinoma and squamous cell carcinoma is possible . | {
"id": "C0027651",
"pos": [
60,
66
],
"name": "tumour"
} | {
"id": "C0040300",
"pos": [
91,
97
],
"name": "tissue"
} | 0NA |
Moreover , medications introduced before the increased pre-marketing regulations and post-marketing monitoring systems instituted after the thalidomide tragedy have little relevance when considering the present drug safety picture because the circumstances under which they were introduced were completely different . | {
"id": "C0013227",
"pos": [
11,
22
],
"name": "medications"
} | {
"id": "C0039736",
"pos": [
140,
151
],
"name": "thalidomide"
} | 0NA |
AFC blockade is therefore probably only relevant in the suppression of ( primary ? ) IgM responses by large doses of tolerogen . | {
"id": "C0020861",
"pos": [
85,
88
],
"name": "IgM"
} | {
"id": "C0221103",
"pos": [
56,
67
],
"name": "suppression"
} | 0NA |
It may not only contribute to a better understanding of the neoplastic process but also provide a base for safer assessment of cancer risk during surveillance for early detection of esophageal adenocarcinoma . | {
"id": "C0031809",
"pos": [
113,
123
],
"name": "assessment"
} | {
"id": "C0279628",
"pos": [
182,
207
],
"name": "esophageal adenocarcinoma"
} | 0NA |
After proved contact with a hepatitis patient , infection can be prevented by timely treatment with hyperimmune serum . | {
"id": "C0009450",
"pos": [
48,
57
],
"name": "infection"
} | {
"id": "C0019158",
"pos": [
28,
37
],
"name": "hepatitis"
} | 0NA |
The objective was to study the effects of a hearing aid use intervention on neurocognitive and psychosocial functioning in individuals with SNHL aged ≥55 years . | {
"id": "C0018784",
"pos": [
140,
144
],
"name": "SNHL"
} | {
"id": "C0018767",
"pos": [
44,
51
],
"name": "hearing"
} | 15interprets |
These results indicate that a debulking procedure and locoregional treatment of peritoneal metastases is associated with an increased level of 5-FU in the tumours . | {
"id": "C0027651",
"pos": [
155,
162
],
"name": "tumours"
} | {
"id": "C0016360",
"pos": [
143,
147
],
"name": "5-FU"
} | 0NA |
ADP from activated platelets is recognized as major factor in thrombus formation and is a potent stimulator of oxygen-free radical release from neutrophils . | {
"id": "C0001459",
"pos": [
0,
3
],
"name": "ADP"
} | {
"id": "C0175727",
"pos": [
97,
107
],
"name": "stimulator"
} | 0NA |
One chemical mechanism that is consistent with the reversibility of block and the observed lack of effect of 8-Br-cGMP on conduction is the formation of a nitrosothiol through reaction of NO with a sulfhydryl group . | {
"id": "C0028778",
"pos": [
68,
73
],
"name": "block"
} | {
"id": "C0220806",
"pos": [
4,
12
],
"name": "chemical"
} | 0NA |
The brain also expresses CYP epoxygenases that convert AA to the vasodilator epoxyeicosatrienoic acids ( EETs ) , the production of which increases in ischemia and provide protection against ischemia-induced tissue damage . | {
"id": "C0006104",
"pos": [
4,
9
],
"name": "brain"
} | {
"id": "C0022116",
"pos": [
151,
159
],
"name": "ischemia"
} | 0NA |
For nicotine , alcohol , and cannabis , familial environmental factors were critical in influencing use in early adolescence and gradually declined in importance through young adulthood . | {
"id": "C0028040",
"pos": [
4,
12
],
"name": "nicotine"
} | {
"id": "C0001962",
"pos": [
15,
22
],
"name": "alcohol"
} | 0NA |
Patients were found to have elevated levels of IL-8 in BAL fluid compared to control subjects ( p < 0.01 ) . | {
"id": "C0005889",
"pos": [
59,
64
],
"name": "fluid"
} | {
"id": "C0012383",
"pos": [
55,
58
],
"name": "BAL"
} | 0NA |
Bayesian analysis allows calculation of the probability of a particular hypothesis , either disease or carrier status , based on family information and/or genetic test results . | {
"id": "C0012634",
"pos": [
92,
99
],
"name": "disease"
} | {
"id": "C0679560",
"pos": [
155,
167
],
"name": "genetic test"
} | 0NA |
This research proves cost-effectiveness of the use of aspirin in the primary prevention of MI in targeted population , since the assessed ICERs are quite under the recommended threshold by WHO which is one gross domestic product ( GDP ) per capita ( $ 5315.1 for Iran in 2015 ) . | {
"id": "C0018340",
"pos": [
231,
234
],
"name": "GDP"
} | {
"id": "C0004057",
"pos": [
54,
61
],
"name": "aspirin"
} | 0NA |
In an attempt to identify dorsal root ganglion ( DRG ) neurons that use glutamic acid as a neurotransmitter , [3H]D-aspartate ( [3H]D-Asp ) was chosen as a marker , since it is a metabolically inert amino acid known to be taken up by the same affinity mechanism as L-aspartate and L-glutamate . | {
"id": "C0002520",
"pos": [
199,
209
],
"name": "amino acid"
} | {
"id": "C0220839",
"pos": [
281,
292
],
"name": "L-glutamate"
} | 0NA |
Magnetic resonance ( MR ) imaging-based temperature monitoring has gained interest for use in general hyperthermia treatment of tumors . | {
"id": "C0015967",
"pos": [
102,
114
],
"name": "hyperthermia"
} | {
"id": "C0005903",
"pos": [
40,
51
],
"name": "temperature"
} | 15interprets |
The present study , therefore , indicates that the most common pathogenesis of RDC has a basic condition of avascular necrosis in the femoral head in the elderly , in addition , the accompanying rapid destruction appears to be related to an immunological abnormality . | {
"id": "C0015813",
"pos": [
134,
146
],
"name": "femoral head"
} | {
"id": "C0027543",
"pos": [
108,
126
],
"name": "avascular necrosis"
} | 0NA |
Taken together , our meta-analysis had suggested an increased risk role of XRCC3 241MM genotype in bladder cancer among all subjects , and the effect of T241 M polymorphism on bladder susceptibility should be studied with a larger , stratified population . | {
"id": "C0005682",
"pos": [
176,
183
],
"name": "bladder"
} | {
"id": "C0005684",
"pos": [
99,
113
],
"name": "bladder cancer"
} | 11finding_site_of |
Intravitreal injections of two different antisense phosphorothioate oligodeoxynucleotides prior to the onset of proliferative retinopathy reduced new blood vessel growth a mean of 25 and 31 % compared with controls . | {
"id": "C0005847",
"pos": [
150,
162
],
"name": "blood vessel"
} | {
"id": "C0339467",
"pos": [
112,
137
],
"name": "proliferative retinopathy"
} | 0NA |
Right parotid gland biopsy showed abundant IgG4-positive plasma cells . | {
"id": "C0005558",
"pos": [
20,
26
],
"name": "biopsy"
} | {
"id": "C0227456",
"pos": [
0,
19
],
"name": "Right parotid gland"
} | 0NA |
The follow-up for 3 - 12 months revealed that all the flaps and skin grafts had a good appearance with no contracture of the skin . | {
"id": "C0037297",
"pos": [
64,
75
],
"name": "skin grafts"
} | {
"id": "C0038925",
"pos": [
54,
59
],
"name": "flaps"
} | 0NA |
Our results suggested that CP-99 994 could improve emesis induced by cisplatin by regulating gastric motility and gastric related neuronal activity in the DMNV . | {
"id": "C0008838",
"pos": [
71,
80
],
"name": "cisplatin"
} | {
"id": "C0042963",
"pos": [
53,
59
],
"name": "emesis"
} | 0NA |
Twenty ( 50 % ) enthesophytes were located above the PF , 16 ( 40 % ) between the fascia and abductor digiti minimi , flexor digitorum brevis and abductor hallucis muscles , and only one ( 3 % ) was located within the PF . | {
"id": "C0015641",
"pos": [
82,
88
],
"name": "fascia"
} | {
"id": "C0000741",
"pos": [
93,
115
],
"name": "abductor digiti minimi"
} | 0NA |
Emphasis was focused on total glucagon and gastrointestinal glucagon ( GLI ) concentrations , but measurements of these parameters were supplemented by determinations of glucose and triglyceride . | {
"id": "C0041004",
"pos": [
182,
194
],
"name": "triglyceride"
} | {
"id": "C0017725",
"pos": [
170,
177
],
"name": "glucose"
} | 0NA |
The centrality of communicating in human life means that communication difficulties are experienced at a deeply personal level and have significant implications for identity . | {
"id": "C1299586",
"pos": [
71,
83
],
"name": "difficulties"
} | {
"id": "C0424215",
"pos": [
165,
173
],
"name": "identity"
} | 0NA |
Rather , specific articles that selectively address the question of nephrotoxicity related to the osmolar content of contrast media were used for discussion . | {
"id": "C0557061",
"pos": [
146,
156
],
"name": "discussion"
} | {
"id": "C0009924",
"pos": [
117,
131
],
"name": "contrast media"
} | 0NA |
Many neurons in macaque lateral intraparietal cortex ( LIP ) maintain elevated activity induced by visual or auditory targets during tasks in which monkeys are required to withhold one or more planned eye movements . | {
"id": "C0023759",
"pos": [
55,
58
],
"name": "LIP"
} | {
"id": "C0026649",
"pos": [
205,
214
],
"name": "movements"
} | 0NA |
This study aimed to evaluate the diagnostic utilities of the automated connective tissues disease screening assay , CTD screen , in patients with systemic rheumatic diseases . | {
"id": "C0009780",
"pos": [
71,
89
],
"name": "connective tissues"
} | {
"id": "C0035435",
"pos": [
155,
173
],
"name": "rheumatic diseases"
} | 0NA |
Scepticism and critical attitudes towards immunisation have prevailed since the introduction of the smallpox vaccine . | {
"id": "C0020971",
"pos": [
42,
54
],
"name": "immunisation"
} | {
"id": "C0042210",
"pos": [
109,
116
],
"name": "vaccine"
} | 0NA |
In quadrant 1 the amplitudes of the amblyopic eyes and fellow eyes were significantly different at the time of diagnosis ( p = 0.005 ) , whereas after occlusion treatment there was no significant difference ( p = 0.888 ) . | {
"id": "C0001168",
"pos": [
155,
164
],
"name": "occlusion"
} | {
"id": "C0015392",
"pos": [
62,
66
],
"name": "eyes"
} | 0NA |
Variant 1 , with abnormal glycosylation , had reduced heparin affinity and severely affected reactivity with the target proteases . | {
"id": "C0205161",
"pos": [
19,
27
],
"name": "abnormal"
} | {
"id": "C0019134",
"pos": [
56,
63
],
"name": "heparin"
} | 0NA |
Fibrillation ( 76 % ) , detachment ( 50 % ) , rupture ( 35 % ) , and ossification ( 21 % ) of the glenoid labrum were the most frequent alterations in our autopsy material . | {
"id": "C0004398",
"pos": [
155,
162
],
"name": "autopsy"
} | {
"id": "C0029433",
"pos": [
69,
81
],
"name": "ossification"
} | 0NA |
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