instruction stringlengths 158 1.42k | input stringlengths 46 1.96k | response stringclasses 11 values |
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<Instruct>: Given the context 'Naloxone reverses the antihypertensive effect of clonidine.', select the correct biomedical concept corresponding to 'naloxone'. Answer using one of the provided options. | <Options>: A: naloxone mb (aka n-methylnaloxone)
B: naloxone-3-o-methyl-oxime
C: naloxone-6-hydrazone (aka naloxazone)
D: naloxone, buprenorphine (aka buprenorphine, naloxone drug combination)
E: naloxone, (5 beta,9 alpha,13 alpha,14 alpha)-isomer (aka naloxone)
F: nalorphine
G: None of the above. | E |
<Instruct>: Given the context 'Naloxone reverses the antihypertensive effect of clonidine.', select the correct biomedical concept corresponding to 'clonidine'. Answer using one of the provided options. | <Options>: A: 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline (aka lofexidine)
B: 2-(n-allyl-n-(2,6-dichlorophenyl)amino)-2-imidazoline (aka alinidine)
C: hpaa-clonidine (aka hydroxyphenacetyl aminoclonidine)
D: 1h-imidazol-2-amine, n-(2,6-dichlorophenyl)-4,5-dihydro- (aka clonidine)
E: 2,6-dimethyl clonidine (aka 2,6-dimethylclonidine)
F: clonidine para-isothiocyanate (aka clonidine 4-isothiocyanate)
G: 2-(2,6-dichlorophenyloxy)-2-imidazoline
H: clonixin
I: clds (aka clonidine-displacing substance)
J: None of the above. | D |
<Instruct>: Given the context 'In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by intravenous clonidine, 5 to 20 micrograms/kg, was inhibited or reversed by nalozone, 0.2 to 2 mg/kg.', select the correct biomedical concept corresponding to 'clonidine'. Answer using one of the provided options. | <Options>: A: 2,6-dimethyl clonidine (aka 2,6-dimethylclonidine)
B: 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline (aka lofexidine)
C: 2-(2,6-dichlorophenyloxy)-2-imidazoline
D: hpaa-clonidine (aka hydroxyphenacetyl aminoclonidine)
E: clonidine para-isothiocyanate (aka clonidine 4-isothiocyanate)
F: clonixin
G: clonidine-displacing substance
H: clonidine monohydrochloride (aka clonidine)
I: 2-(n-allyl-n-(2,6-dichlorophenyl)amino)-2-imidazoline (aka alinidine)
J: None of the above. | H |
<Instruct>: Given the context 'The hypotensive effect of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone.', select the correct biomedical concept corresponding to 'alpha-methyldopa'. Answer using one of the provided options. | <Options>: A: alpha methyldopa (aka methyldopa)
B: 3-o-methyldopamine (aka 3-methoxytyramine)
C: 3-o-methyl-methyldopa (aka 3-o-methylmethyldopa)
D: poe methyldopa (aka methyldopa pivaloyloxyethyl ester)
E: 3-o-methyl-alpha-methyldopamine
F: 3-o-methyldopa (aka 3-methoxytyrosine)
G: alpha-methyldopamine, (r)-isomer (aka alpha-methyldopamine)
H: methyldopamine (aka deoxyepinephrine)
I: None of the above. | A |
<Instruct>: Given the context 'The hypotensive effect of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone.', select the correct biomedical concept corresponding to 'naloxone'. Answer using one of the provided options. | <Options>: A: nalorphine
B: naloxone-3-o-methyl-oxime
C: naloxone hydrochloride (aka naloxone)
D: naloxone-6-hydrazone (aka naloxazone)
E: naloxone, buprenorphine (aka buprenorphine, naloxone drug combination)
F: naloxone mb (aka n-methylnaloxone)
G: None of the above. | C |
<Instruct>: Given the context 'Naloxone alone did not affect either blood pressure or heart rate.', select the correct biomedical concept corresponding to 'naloxone'. Answer using one of the provided options. | <Options>: A: nalorphine
B: naloxone hydrochloride dihydride (aka naloxone)
C: naloxone-3-o-methyl-oxime
D: naloxone, buprenorphine (aka buprenorphine, naloxone drug combination)
E: naloxone mb (aka n-methylnaloxone)
F: naloxone-6-hydrazone (aka naloxazone)
G: None of the above. | B |
<Instruct>: Given the context 'In brain membranes from spontaneously hypertensive rats clonidine, 10(-8) to 10(-5) M, did not influence stereoselective binding of [3H]-naloxone (8 nM), and naloxone, 10(-8) to 10(-4) M, did not influence clonidine-suppressible binding of [3H]-dihydroergocryptine (1 nM).', select the correct biomedical concept corresponding to 'clonidine'. Answer using one of the provided options. | <Options>: A: 2-(n-allyl-n-(2,6-dichlorophenyl)amino)-2-imidazoline (aka alinidine)
B: 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline (aka lofexidine)
C: clonidine dihydrochloride (aka clonidine)
D: clonixin
E: 2-(2,6-dichlorophenyloxy)-2-imidazoline
F: clds (aka clonidine-displacing substance)
G: 2,6-dimethyl clonidine (aka 2,6-dimethylclonidine)
H: clonidine para-isothiocyanate (aka clonidine 4-isothiocyanate)
I: hpaa-clonidine (aka hydroxyphenacetyl aminoclonidine)
J: None of the above. | C |
<Instruct>: Given the context 'In brain membranes from spontaneously hypertensive rats clonidine, 10(-8) to 10(-5) M, did not influence stereoselective binding of [3H]-naloxone (8 nM), and naloxone, 10(-8) to 10(-4) M, did not influence clonidine-suppressible binding of [3H]-dihydroergocryptine (1 nM).', select the correct biomedical concept corresponding to 'naloxone'. Answer using one of the provided options. | <Options>: A: naloxone, buprenorphine (aka buprenorphine, naloxone drug combination)
B: naloxone-6-hydrazone (aka naloxazone)
C: nalorphine
D: naloxone methobromide (aka n-methylnaloxone)
E: naloxone-3-o-methyl-oxime
F: naloxone, (5 beta,9 alpha,13 alpha,14 alpha)-isomer (aka naloxone)
G: None of the above. | F |
<Instruct>: Given the context 'In brain membranes from spontaneously hypertensive rats clonidine, 10(-8) to 10(-5) M, did not influence stereoselective binding of [3H]-naloxone (8 nM), and naloxone, 10(-8) to 10(-4) M, did not influence clonidine-suppressible binding of [3H]-dihydroergocryptine (1 nM).', select the correct biomedical concept corresponding to 'clonidine'. Answer using one of the provided options. | <Options>: A: clonidine monohydrochloride (aka clonidine)
B: 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline (aka lofexidine)
C: clonixin
D: hpaa-clonidine (aka hydroxyphenacetyl aminoclonidine)
E: 2-(2,6-dichlorophenyloxy)-2-imidazoline
F: 2,6-dimethyl clonidine (aka 2,6-dimethylclonidine)
G: 2-(n-allyl-n-(2,6-dichlorophenyl)amino)-2-imidazoline (aka alinidine)
H: clds (aka clonidine-displacing substance)
I: 4-isothiocyanato clonidine (aka clonidine 4-isothiocyanate)
J: None of the above. | A |
<Instruct>: Given the context 'As naloxone and clonidine do not appear to interact with the same receptor site, the observed functional antagonism suggests the release of an endogenous opiate by clonidine or alpha-methyldopa and the possible role of the opiate in the central control of sympathetic tone.', select the correct biomedical concept corresponding to 'naloxone'. Answer using one of the provided options. | <Options>: A: nalorphine
B: naloxone-6-hydrazone (aka naloxazone)
C: naloxone methiodide (aka n-methylnaloxone)
D: naloxone-3-o-methyl-oxime
E: naloxone, buprenorphine (aka buprenorphine, naloxone drug combination)
F: naloxone
G: None of the above. | F |
<Instruct>: Given the context 'As naloxone and clonidine do not appear to interact with the same receptor site, the observed functional antagonism suggests the release of an endogenous opiate by clonidine or alpha-methyldopa and the possible role of the opiate in the central control of sympathetic tone.', select the correct biomedical concept corresponding to 'clonidine'. Answer using one of the provided options. | <Options>: A: 2-(n-allyl-n-(2,6-dichlorophenyl)amino)-2-imidazoline (aka alinidine)
B: hydrochloride, clonidine (aka clonidine)
C: 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline (aka lofexidine)
D: 4-isothiocyanato clonidine (aka clonidine 4-isothiocyanate)
E: 2,6-dimethyl clonidine (aka 2,6-dimethylclonidine)
F: hpaa-clonidine (aka hydroxyphenacetyl aminoclonidine)
G: 2-(2,6-dichlorophenyloxy)-2-imidazoline
H: clonixin
I: clonidine-displacing substance
J: None of the above. | B |
<Instruct>: Given the context 'As naloxone and clonidine do not appear to interact with the same receptor site, the observed functional antagonism suggests the release of an endogenous opiate by clonidine or alpha-methyldopa and the possible role of the opiate in the central control of sympathetic tone.', select the correct biomedical concept corresponding to 'clonidine'. Answer using one of the provided options. | <Options>: A: 2-(2,6-dichlorophenyloxy)-2-imidazoline
B: hpaa-clonidine (aka hydroxyphenacetyl aminoclonidine)
C: 2,6-dimethyl clonidine (aka 2,6-dimethylclonidine)
D: 2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline (aka lofexidine)
E: clonixin
F: clonidine para-isothiocyanate (aka clonidine 4-isothiocyanate)
G: 2-(n-allyl-n-(2,6-dichlorophenyl)amino)-2-imidazoline (aka alinidine)
H: clonidine hydrochloride (aka clonidine)
I: clds (aka clonidine-displacing substance)
J: None of the above. | H |
<Instruct>: Given the context 'As naloxone and clonidine do not appear to interact with the same receptor site, the observed functional antagonism suggests the release of an endogenous opiate by clonidine or alpha-methyldopa and the possible role of the opiate in the central control of sympathetic tone.', select the correct biomedical concept corresponding to 'alpha-methyldopa'. Answer using one of the provided options. | <Options>: A: 3-o-methylmethyldopa
B: 3-o-methyldopamine (aka 3-methoxytyramine)
C: methyldopamine (aka deoxyepinephrine)
D: poe methyldopa (aka methyldopa pivaloyloxyethyl ester)
E: 3-o-methyldopa (aka 3-methoxytyrosine)
F: alpha-methyldopamine
G: 3-o-methyl-alpha-methyldopamine
H: alpha methyl l dopa (aka methyldopa)
I: None of the above. | H |
<Instruct>: Given the context 'Lidocaine-induced cardiac asystole.', select the correct biomedical concept corresponding to 'lidocaine'. Answer using one of the provided options. | <Options>: A: leocaine
B: lidan
C: o-(2-diethylaminoethyl)-2',6'-mandeloxylidide
D: 2-2etn-2mephacn (aka lidocaine)
E: lidol (aka meperidine)
F: 2-chloro-n-(2,6-diethylphenyl)acetamide
G: lidemol (aka fluocinonide)
H: 2-(dimethylamino)-n-(2,6-dimethylphenyl)acetamide
I: n-(2-diethylaminoethyl)-2',6'-mandeloxylidide
J: n-(beta-phenylethyl)lidocaine (aka tonicaine)
K: None of the above. | D |
<Instruct>: Given the context 'Intravenous administration of a single 50-mg bolus of lidocaine in a 67-year-old man resulted in profound depression of the activity of the sinoatrial and atrioventricular nodal pacemakers.', select the correct biomedical concept corresponding to 'lidocaine'. Answer using one of the provided options. | <Options>: A: lidocaine monoacetate (aka lidocaine)
B: lidemol (aka fluocinonide)
C: 2-chloro-n-(2,6-diethylphenyl)acetamide
D: lidan
E: n-(2-diethylaminoethyl)-2',6'-mandeloxylidide
F: lidofenin
G: 2-(dimethylamino)-n-(2,6-dimethylphenyl)acetamide
H: o-(2-diethylaminoethyl)-2',6'-mandeloxylidide
I: n-(beta-phenylethyl)lidocaine (aka tonicaine)
J: acetamide, 2-(diethylamino)-n-(2,4,6-trimethylphenyl)- (aka trimecaine)
K: None of the above. | A |
<Instruct>: Given the context 'The patient had no apparent associated conditions which might have predisposed him to the development of bradyarrhythmias; and, thus, this probably represented a true idiosyncrasy to lidocaine.', select the correct biomedical concept corresponding to 'lidocaine'. Answer using one of the provided options. | <Options>: A: lidol (aka meperidine)
B: 2-chloro-n-(2,6-diethylphenyl)acetamide
C: o-(2-diethylaminoethyl)-2',6'-mandeloxylidide
D: n-(2-diethylaminoethyl)-2',6'-mandeloxylidide
E: methyl-lidocaine (aka n-methyllidocaine)
F: 2-(dimethylamino)-n-(2,6-dimethylphenyl)acetamide
G: lidemol (aka fluocinonide)
H: acetamide, 2-(diethylamino)-n-(2,4,6-trimethylphenyl)- (aka trimecaine)
I: leocaine
J: lidocaine
K: None of the above. | J |
<Instruct>: Given the context 'Suxamethonium infusion rate and observed fasciculations.', select the correct biomedical concept corresponding to 'suxamethonium'. Answer using one of the provided options. | <Options>: A: benzohexonium
B: suxethonium bromide (aka suxethonium)
C: n,n-di-(beta-steaorylethyl)-n,n-dimethylammonium
D: bromide, suxamethonium (aka succinylcholine)
E: isometamidium (aka isometamidium chloride)
F: decamethonium dihydroxide (aka decamethonium)
G: hexadecamethonium
H: trimethylselenonium
I: hexamethonium
J: None of the above. | D |
<Instruct>: Given the context 'Suxamethonium chloride (Sch) was administered i.v. to 36 adult males at six rates: 0.25 mg s-1 to 20 mg s-1.', select the correct biomedical concept corresponding to 'suxamethonium chloride'. Answer using one of the provided options. | <Options>: A: suxethonium bromide (aka suxethonium)
B: (2-(3,4-dimethoxyphenyl)ethyl)dimethylselenonium chloride (aka (2-(3,4-dimethoxyphenyl)ethyl)dimethylselenonium)
C: methionylmethylsulfonium chloride
D: n,n-di-(beta-steaorylethyl)-n,n-dimethylammonium chloride (aka n,n-di-(beta-steaorylethyl)-n,n-dimethylammonium)
E: methylmethioninesulfonium chloride (aka vitamin u)
F: methylbenzethonium chloride
G: chloride, benzethonium (aka benzethonium)
H: suxamethonium (aka succinylcholine)
I: furtrethonium chloride (aka furtrethonium)
J: benzoxonium chloride
K: None of the above. | H |
<Instruct>: Given the context 'Suxamethonium chloride (Sch) was administered i.v. to 36 adult males at six rates: 0.25 mg s-1 to 20 mg s-1.', select the correct biomedical concept corresponding to 'sch'. Answer using one of the provided options. | <Options>: A: sch-a compound
B: schisanartane
C: sch 1000 (aka ipratropium)
D: schiartane
E: schorl
F: sch-p (aka stilbazochrome-p)
G: schmitterite
H: schisanhenol
I: sch 036
J: sch bt2 (aka 2-furan-2-yl-7-3-(4-(4-(4-methylpiperazine-1-sulfonyl)phenylethyl)-7h-pyrazolo(4,3-e)(1,2,4)triazolo-(1,5-c)pyrimdin-5-ylamine))
K: None of the above. | K |
<Instruct>: Given the context 'The infusion was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when Sch 120 mg was exceeded.', select the correct biomedical concept corresponding to 'sch'. Answer using one of the provided options. | <Options>: A: schorl
B: schumannificine
C: sch-p (aka stilbazochrome-p)
D: sch6
E: schisanartane
F: schinol (aka masticadienolic acid)
G: sch bt2 (aka 2-furan-2-yl-7-3-(4-(4-(4-methylpiperazine-1-sulfonyl)phenylethyl)-7h-pyrazolo(4,3-e)(1,2,4)triazolo-(1,5-c)pyrimdin-5-ylamine))
H: sangc (aka s-acetyl-n-glycylcysteamine)
I: sch 036
J: schiartane
K: None of the above. | K |
<Instruct>: Given the context 'Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine).', select the correct biomedical concept corresponding to 'galanthamine hydrobromide'. Answer using one of the provided options. | <Options>: A: galanthamine (aka galantamine)
B: aniline hydrobromide (aka aniline)
C: apohemanthamine
D: higenamine hydrobromide, (+-)-isomer (aka higenamine)
E: nigeglanine hydrobromide (aka nigeglanine)
F: norgalanthamine
G: benzylamine hydrobromide (aka benzylamine)
H: 2-aminotetralin hydrobromide (aka 2-aminotetralin)
I: adtn hydrobromide (aka adtn)
J: amaryllidaceae alkaloids, galanthamine-type (aka amaryllidaceae alkaloids)
K: None of the above. | A |
<Instruct>: Given the context 'Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine).', select the correct biomedical concept corresponding to 'scopolamine'. Answer using one of the provided options. | <Options>: A: methiodide, hyoscine (aka n-methylscopolamine)
B: hyoscine n-oxide
C: transderm scop (aka scopolamine)
D: scopathricin
E: scopolamines (aka scopolamine derivatives)
F: scopolin
G: scopadulin
H: diacetyl scopadol (aka diacetylscopadol)
I: scopolan (aka butylscopolammonium bromide)
J: scoparasin b
K: None of the above. | C |
<Instruct>: Given the context 'Galanthamine hydrobromide, a longer acting anticholinesterase drug, in the treatment of the central effects of scopolamine (Hyoscine).', select the correct biomedical concept corresponding to 'hyoscine'. Answer using one of the provided options. | <Options>: A: hyoscine n-oxide hydrobromide (aka hyoscine n-oxide)
B: protoneodioscin
C: methobromide, hyoscine (aka n-methylscopolamine)
D: hyoscine (aka scopolamine)
E: epimeloscine (aka meloscine)
F: scopolamines (aka scopolamine derivatives)
G: scopolan (aka butylscopolammonium bromide)
H: None of the above. | D |
<Instruct>: Given the context 'Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage.', select the correct biomedical concept corresponding to 'galanthamine hydrobromide'. Answer using one of the provided options. | <Options>: A: 2-aminotetralin hydrobromide (aka 2-aminotetralin)
B: galanthaminone
C: galanthamine (aka galantamine)
D: nigeglanine hydrobromide (aka nigeglanine)
E: norgalanthamine
F: haemanthamine (aka hemanthamine)
G: apohaemanthamine (aka apohemanthamine)
H: apogalanthamine
I: higenamine hydrobromide, (+-)-isomer (aka higenamine)
J: galanthamine type amaryllidaceae alkaloids (aka amaryllidaceae alkaloids)
K: None of the above. | C |
<Instruct>: Given the context 'Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage.', select the correct biomedical concept corresponding to 'scopolamine'. Answer using one of the provided options. | <Options>: A: diacetyl scopadol (aka diacetylscopadol)
B: hyoscine n-oxide
C: scopathricin
D: scoparasin b
E: scopolan (aka butylscopolammonium bromide)
F: scopadulin
G: scopolin
H: scopace (aka scopolamine)
I: derivatives, scopolamine (aka scopolamine derivatives)
J: methiodide, hyoscine (aka n-methylscopolamine)
K: None of the above. | H |
<Instruct>: Given the context 'Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage.', select the correct biomedical concept corresponding to 'hyoscine'. Answer using one of the provided options. | <Options>: A: scopolamine cooper (aka scopolamine)
B: n-butylbromide, hyoscine (aka butylscopolammonium bromide)
C: methobromide, hyoscine (aka n-methylscopolamine)
D: protoneodioscin
E: scopolamines (aka scopolamine derivatives)
F: hyoscine n-oxide
G: epimeloscine (aka meloscine)
H: None of the above. | A |
<Instruct>: Given the context 'It is longer acting than physostigmine and is used in anaesthesia to reverse the non-depolarizing neuromuscular block.', select the correct biomedical concept corresponding to 'physostigmine'. Answer using one of the provided options. | <Options>: A: physostigmine-n-oxide
B: physacoztomatin
C: physalemin (aka physalaemin)
D: prostigmine (aka neostigmine)
E: norneostigmine
F: quilostigmine
G: 1-methylphysostigmine
H: physostigmine methiodide
I: physovenine
J: physostigmine
K: None of the above. | J |
<Instruct>: Given the context 'However, studies into the dose necessary to combating scopolamine intoxication are indicated.', select the correct biomedical concept corresponding to 'scopolamine'. Answer using one of the provided options. | <Options>: A: scopolin
B: scopolamines (aka scopolamine derivatives)
C: scopathricin
D: scopolamine hydrobromide (aka scopolamine)
E: hyoscine n-oxide stereoisomer (aka hyoscine n-oxide)
F: diacetyl scopadol (aka diacetylscopadol)
G: scoparasin b
H: methiodide, hyoscine (aka n-methylscopolamine)
I: scopadulin
J: scopolan (aka butylscopolammonium bromide)
K: None of the above. | D |
<Instruct>: Given the context 'Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium compounds
B: lithium-9
C: lithium-3
D: lithium-8
E: lithium gluconate (aka gluconic acid)
F: lithium-6
G: lithium chloride (licl) (aka lithium chloride)
H: lithium citrate
I: bicarbonate, lithium (aka lithium carbonate)
J: lithium
K: None of the above. | J |
<Instruct>: Given the context 'Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium-4
B: lithium-9
C: lithium chloride (licl) (aka lithium chloride)
D: lithium-3
E: bicarbonate, lithium (aka lithium carbonate)
F: lithium-5
G: lithium 7 (aka lithium)
H: lithium sulfide
I: lithium compounds
J: lithium-6
K: None of the above. | G |
<Instruct>: Given the context 'Newborn female Wistar rats were fed a lithium-containing diet (50 mmol/kg) for 8 weeks and then randomized to normal diet, HP diet (40 vs. 19%), NX or HP+NX for another 8 weeks.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium-8
B: lithium citrate
C: lithium-11
D: lithium-4
E: lithium-3
F: lithium-5
G: lithium
H: compounds, lithium (aka lithium compounds)
I: lithium sulfide
J: lithium gluconate (aka gluconic acid)
K: None of the above. | G |
<Instruct>: Given the context 'Corresponding non-lithium pretreated groups were generated.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium-9
B: lithium citrate
C: lithium-8
D: chloride, lithium (aka lithium chloride)
E: lithium-11
F: lithium-3
G: lithium-7 (aka lithium)
H: lithium-4
I: carbonate, lithium (aka lithium carbonate)
J: lithium compounds
K: None of the above. | G |
<Instruct>: Given the context 'When comparing all lithium treated versus non-lithium-treated groups, lithium caused a reduction in glomerular filtration rate (GFR) without significant changes in effective renal plasma flow (as determined by a marker secreted into the proximal tubules) or lithium clearance.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium gluconate (aka gluconic acid)
B: lithium-6
C: lithium sulfide
D: lithium-5
E: lithium-8
F: lithium-3
G: lithium-9
H: lithium-7 (aka lithium)
I: lithium chloride
J: lithium citrate
K: None of the above. | H |
<Instruct>: Given the context 'When comparing all lithium treated versus non-lithium-treated groups, lithium caused a reduction in glomerular filtration rate (GFR) without significant changes in effective renal plasma flow (as determined by a marker secreted into the proximal tubules) or lithium clearance.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium
B: lithium-8
C: lithium-6
D: lithium sulfide
E: bicarbonate, lithium (aka lithium carbonate)
F: lithium-4
G: lithium-11
H: lithium gluconate (aka gluconic acid)
I: chloride, lithium (aka lithium chloride)
J: lithium-9
K: None of the above. | A |
<Instruct>: Given the context 'When comparing all lithium treated versus non-lithium-treated groups, lithium caused a reduction in glomerular filtration rate (GFR) without significant changes in effective renal plasma flow (as determined by a marker secreted into the proximal tubules) or lithium clearance.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium-7 (aka lithium)
B: lithium chloride (licl) (aka lithium chloride)
C: lithium-6
D: lithium-9
E: lithium-11
F: lithium-4
G: carbonate, lithium (aka lithium carbonate)
H: lithium-5
I: lithium-8
J: lithium-3
K: None of the above. | A |
<Instruct>: Given the context 'When comparing all lithium treated versus non-lithium-treated groups, lithium caused a reduction in glomerular filtration rate (GFR) without significant changes in effective renal plasma flow (as determined by a marker secreted into the proximal tubules) or lithium clearance.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium-9
B: lithium chloride (licl) (aka lithium chloride)
C: lithium gluconate (aka gluconic acid)
D: carbonate, lithium (aka lithium carbonate)
E: lithium-8
F: lithium sulfide
G: lithium-4
H: lithium-11
I: lithium-7 (aka lithium)
J: lithium-3
K: None of the above. | I |
<Instruct>: Given the context 'Consequently, lithium pretreatment caused a fall in filtration fraction and an increase in fractional Li excretion.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium chloride (licl) (aka lithium chloride)
B: lithium-6
C: compounds, lithium (aka lithium compounds)
D: lithium
E: lithium citrate
F: lithium gluconate (aka gluconic acid)
G: lithium-4
H: lithium-5
I: carbonate, lithium (aka lithium carbonate)
J: lithium sulfide
K: None of the above. | D |
<Instruct>: Given the context 'Consequently, lithium pretreatment caused a fall in filtration fraction and an increase in fractional Li excretion.', select the correct biomedical concept corresponding to 'li'. Answer using one of the provided options. | <Options>: A: liogen (aka fluphenazine depot)
B: lithium
C: li2zro3 (aka lithium zirconate)
D: liyan
E: li(x)coo2 (aka lithium cobalt oxide)
F: li2s compound (aka lithium sulfide)
G: chloride, lithium (aka lithium chloride)
H: litreol (aka 3-(pentadec-10-enyl)catechol)
I: liotrix (aka thyroxine, triiodothyronine drug combination)
J: lithium-4
K: None of the above. | B |
<Instruct>: Given the context 'Lithium also caused proteinuria and systolic hypertension in absence of glomerulosclerosis.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium-4
B: lithium
C: lithium gluconate (aka gluconic acid)
D: lithium sulfide
E: lithium-8
F: lithium-3
G: lithium-5
H: lithium-6
I: chloride, lithium (aka lithium chloride)
J: bicarbonate, lithium (aka lithium carbonate)
K: None of the above. | B |
<Instruct>: Given the context 'HP failed to accentuante progression of renal failure and in fact tended to increase GFR and decrease plasma creatinine levels in lithium pretreated rats.', select the correct biomedical concept corresponding to 'creatinine'. Answer using one of the provided options. | <Options>: A: creat whole extract (aka andrographis paniculata extract)
B: creosol
C: hydrotalcit-ratiopharm (aka hydrotalcite)
D: creatol
E: r(acc) (aka adenylyl-(3'-5')-cytidylyl-(3'-5')-cytidine)
F: 5,7-dihydroxytryptamine creatinine
G: creatine
H: creatinine sulfate salt (aka creatinine)
I: creatinol phosphate
J: triolandren
K: None of the above. | H |
<Instruct>: Given the context 'HP failed to accentuante progression of renal failure and in fact tended to increase GFR and decrease plasma creatinine levels in lithium pretreated rats.', select the correct biomedical concept corresponding to 'lithium'. Answer using one of the provided options. | <Options>: A: lithium-5
B: lithium citrate
C: lithium-4
D: lithium 7 (aka lithium)
E: lithium-3
F: lithium-9
G: lithium-8
H: lithium-11
I: compounds, lithium (aka lithium compounds)
J: lithium gluconate (aka gluconic acid)
K: None of the above. | D |
<Instruct>: Given the context 'NX+HP caused a further rise in blood pressure in Li-pretreated rats.', select the correct biomedical concept corresponding to 'li'. Answer using one of the provided options. | <Options>: A: lithium chloride
B: lithium-8
C: liyan
D: liotrix (aka thyroxine, triiodothyronine drug combination)
E: li-3 radioisotope (aka lithium-3)
F: li2zro3 (aka lithium zirconate)
G: li(x)coo2 (aka lithium cobalt oxide)
H: liogen (aka fluphenazine depot)
I: lithium-4
J: lithium
K: None of the above. | J |
<Instruct>: Given the context 'The results indicate that Li-induced nephropathy, even when the GFR is only modestly reduced, is associated with proteinuria and arterial systolic hypertension.', select the correct biomedical concept corresponding to 'li'. Answer using one of the provided options. | <Options>: A: lithium-8
B: liogen (aka fluphenazine depot)
C: lithium 7 (aka lithium)
D: lithium-3
E: lithium chloride (licl) (aka lithium chloride)
F: litreol (aka 3-(pentadec-10-enyl)catechol)
G: lithium-9
H: li2zro3 (aka lithium zirconate)
I: liyan
J: li-4 radioisotope (aka lithium-4)
K: None of the above. | C |
<Instruct>: Given the context 'Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive properties similar to cyclosporin.', select the correct biomedical concept corresponding to 'fusidic acid'. Answer using one of the provided options. | <Options>: A: fusicoccin-a (aka fusicoccin)
B: acid, fusaric (aka fusaric acid)
C: fuscin
D: fusidin (aka fusidic acid)
E: fusicoccin s
F: fusicoccin r
G: fusidin h
H: fusaminic acid
I: fusaricide
J: fuscinarin
K: None of the above. | D |
<Instruct>: Given the context 'Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive properties similar to cyclosporin.', select the correct biomedical concept corresponding to 'cyclosporin'. Answer using one of the provided options. | <Options>: A: 9-(n-methyl-l-isoleucine)-cyclosporin a (aka (melle-4)cyclosporin)
B: cyclosporin o
C: cyclosporin c
D: cyclosporin d
E: csh cyclosporin (aka cyclosporin h)
F: cyclosporine a (aka cyclosporine)
G: cyclosporin-like substance
H: cyclosporin f
I: cyclosporin a, 2-(o-(2-hydroxyethyl)-d-serine)- (aka sdz imm 125)
J: cyclosporin g
K: None of the above. | F |
<Instruct>: Given the context 'Fusidic acid is an antibiotic with T-cell specific immunosuppressive effects similar to those of cyclosporin.', select the correct biomedical concept corresponding to 'cyclosporin'. Answer using one of the provided options. | <Options>: A: cyclosporin f
B: cyclosporin g
C: 9-(n-methyl-l-isoleucine)-cyclosporin a (aka (melle-4)cyclosporin)
D: cyclosporines (aka cyclosporins)
E: cyclosporin d
F: cyclosporine a (aka cyclosporine)
G: d-serine(8)-cyclosporin (aka cyclosporin, serine(8)-)
H: cyclosporin a, 2-(o-(2-hydroxyethyl)-d-serine)- (aka sdz imm 125)
I: cyclosporin c
J: csh cyclosporin (aka cyclosporin h)
K: None of the above. | F |
<Instruct>: Given the context 'Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics and tolerability of fusidic acid treatment in chronic active, therapy-resistant patients.', select the correct biomedical concept corresponding to 'fusidic acid'. Answer using one of the provided options. | <Options>: A: fusaminic acid
B: fusaricide
C: fusicoccin h
D: fuscinarin
E: fuscine
F: fusaricidin a
G: fuscin
H: fusicoccin s
I: fusidin h
J: fusidin (aka fusidic acid)
K: None of the above. | J |
<Instruct>: Given the context 'Fusidic acid was administered orally in a dose of 500 mg t.d.s.', select the correct biomedical concept corresponding to 'fusidic acid'. Answer using one of the provided options. | <Options>: A: fusafungin
B: fusicoccin r
C: fuscinarin
D: fusaricide
E: fusaric acid
F: fuscin
G: fusidic acid
H: fuscine
I: fusidin h
J: fusicoccin-a (aka fusicoccin)
K: None of the above. | G |
<Instruct>: Given the context 'Five of 8 patients (63%) improved during fusidic acid treatment: 3 at two weeks and 2 after four weeks.', select the correct biomedical concept corresponding to 'fusidic acid'. Answer using one of the provided options. | <Options>: A: fusicoccin
B: fusidin h
C: acid, fusidic (aka fusidic acid)
D: acid, fusaric (aka fusaric acid)
E: fuscine
F: fusafungin
G: fusicoccin s
H: fusicoccin r
I: fusarinolic acid
J: fusaricidin a
K: None of the above. | C |
<Instruct>: Given the context 'The results of this pilot study suggest that fusidic acid may be of benefit in selected chronic active Crohn's disease patients in whom conventional treatment is ineffective.', select the correct biomedical concept corresponding to 'fusidic acid'. Answer using one of the provided options. | <Options>: A: acid, fusaric (aka fusaric acid)
B: fusicoccin r
C: fusidin (aka fusidic acid)
D: fuscin
E: fusicoccin s
F: fusicoccin
G: fuscine
H: (s)-(+)-fusarinolic acid (aka fusarinolic acid)
I: fusafungin
J: fusaricide
K: None of the above. | C |
<Instruct>: Given the context 'Because there seems to exist a scientific rationale for the use of fusidic acid at the cytokine level in inflammatory bowel disease, we suggest that the role of this treatment should be further investigated.', select the correct biomedical concept corresponding to 'fusidic acid'. Answer using one of the provided options. | <Options>: A: fusicoccin h
B: fusaricide
C: fusaminic acid
D: fuscin
E: fusicoccin s
F: fusidic acid
G: fusicoccin r
H: fuscine
I: fusidin h
J: fusicoccin-a (aka fusicoccin)
K: None of the above. | F |
<Instruct>: Given the context 'Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers.', select the correct biomedical concept corresponding to 'cocaine'. Answer using one of the provided options. | <Options>: A: cocotac (aka cocotrimethylammonium chloride)
B: hydrochloride, cocaine (aka cocaine)
C: cocaine n-oxide
D: oil, coconut (aka coconut oil)
E: cocaine methiodide
F: coc compound (aka cholesteryl oleoyl carbonate)
G: cocaine - dipicrylaminate (aka cocaine, dipicrylaminate drug combination)
H: cocaine benzoyl thioester
I: coconut betaine (aka cocobetaine)
J: cocus i (aka 7,8-dihydroxy-2',4',5'-trimethoxyisoflavan)
K: None of the above. | B |
<Instruct>: Given the context 'The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls.', select the correct biomedical concept corresponding to 'cocaine'. Answer using one of the provided options. | <Options>: A: cocobetaine
B: cocaine benzoyl thioester
C: crack cocaine
D: cocus i (aka 7,8-dihydroxy-2',4',5'-trimethoxyisoflavan)
E: hydrochloride, cocaine (aka cocaine)
F: coc compound (aka cholesteryl oleoyl carbonate)
G: cocaine-dipicrylaminate (aka cocaine, dipicrylaminate drug combination)
H: cocaine methiodide
I: cocaine n-oxide
J: n-cyanomethylmethamphetamine
K: None of the above. | E |
<Instruct>: Given the context 'Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block.', select the correct biomedical concept corresponding to 'cocaine'. Answer using one of the provided options. | <Options>: A: cocotac (aka cocotrimethylammonium chloride)
B: cocobetaine
C: coc compound (aka cholesteryl oleoyl carbonate)
D: cocaine n-oxide
E: cocaine hydrochloride (aka cocaine)
F: cocaine methiodide
G: coconut oil
H: cocaine benzoyl thioester
I: cocus i (aka 7,8-dihydroxy-2',4',5'-trimethoxyisoflavan)
J: cocaine, crack (aka crack cocaine)
K: None of the above. | E |
<Instruct>: Given the context 'Sulpiride-induced tardive dystonia.', select the correct biomedical concept corresponding to 'sulpiride'. Answer using one of the provided options. | <Options>: A: sulprim (aka trimethoprim, sulfamethoxazole drug combination)
B: sulprofos
C: sulperazon (aka sulperazone)
D: sulcona
E: sulnate
F: sulisatin sodium (aka sulisatin)
G: n-(((s)-1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide (aka levosulpiride)
H: sulpivert (aka sulpiride)
I: suleparoid
J: sulpyrine (aka dipyrone)
K: None of the above. | H |
<Instruct>: Given the context 'Sulpiride is a selective D2-receptor antagonist with antipsychotic and antidepressant properties.', select the correct biomedical concept corresponding to 'sulpiride'. Answer using one of the provided options. | <Options>: A: sulisatin
B: n-(((s)-1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide (aka levosulpiride)
C: sulnate
D: sulperazon (aka sulperazone)
E: sulprofos
F: sultopride (aka amisulpride)
G: sulpyrin (aka dipyrone)
H: sulproston (aka sulprostone)
I: sulcona
J: sulpivert (aka sulpiride)
K: None of the above. | J |
<Instruct>: Given the context 'Sulpiride is a selective D2-receptor antagonist with antipsychotic and antidepressant properties.', select the correct biomedical concept corresponding to 'antidepressant'. Answer using one of the provided options. | <Options>: A: antipsychotic agent (aka antipsychotic agents)
B: medication, antidepressant (aka antidepressive agents)
C: antidepressants, atypical (aka antidepressive agents, second-generation)
D: antidementia agent (aka nootropic agents)
E: None of the above. | B |
<Instruct>: Given the context 'Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally.', select the correct biomedical concept corresponding to 'sulpiride'. Answer using one of the provided options. | <Options>: A: sulpivert (aka sulpiride)
B: sulprim (aka trimethoprim, sulfamethoxazole drug combination)
C: sultopride (aka amisulpride)
D: sulprofos
E: sulproston (aka sulprostone)
F: sulnate
G: sulisatin sodium (aka sulisatin)
H: suleparoid
I: sulperazon (aka sulperazone)
J: sulpyrine (aka dipyrone)
K: None of the above. | A |
<Instruct>: Given the context 'We studied a 37-year-old man who developed persistent segmental dystonia within 2 months after starting sulpiride therapy.', select the correct biomedical concept corresponding to 'sulpiride'. Answer using one of the provided options. | <Options>: A: sulnate
B: sulcona
C: sultopride hydrochloride (aka amisulpride)
D: sulprim (aka trimethoprim, sulfamethoxazole drug combination)
E: sulprofos
F: sulp (aka sulpiride)
G: sulperazon (aka sulperazone)
H: sulpyrin (aka dipyrone)
I: sulproston (aka sulprostone)
J: n-(((s)-1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide (aka levosulpiride)
K: None of the above. | F |
<Instruct>: Given the context 'We could not find any previous reports of sulpiride-induced tardive dystonia.', select the correct biomedical concept corresponding to 'sulpiride'. Answer using one of the provided options. | <Options>: A: sulcona
B: sulprim (aka trimethoprim, sulfamethoxazole drug combination)
C: sulpyrine (aka dipyrone)
D: sulprofos
E: sulisatin sodium (aka sulisatin)
F: sulperide (aka sulpiride)
G: sulperazon (aka sulperazone)
H: sultopride hydrochloride (aka amisulpride)
I: n-(((s)-1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide (aka levosulpiride)
J: sulproston (aka sulprostone)
K: None of the above. | F |
<Instruct>: Given the context 'Ocular and auditory toxicity in hemodialyzed patients receiving desferrioxamine.', select the correct biomedical concept corresponding to 'desferrioxamine'. Answer using one of the provided options. | <Options>: A: desferrioxamine e
B: desferrioxamine b mesylate (aka deferoxamine)
C: n-hydroxydesferrioxamine b
D: cu(ii)-desferrioxamine (aka copper-desferal complex)
E: desferri-ferricrocin
F: zinc-desferrioxamine
G: deferrioxamine e
H: n-desferriferrichrome
I: mangan-desferrioxamin
J: desferriferrithiocin
K: None of the above. | B |
<Instruct>: Given the context 'During an 18-month period of study 41 hemodialyzed patients receiving desferrioxamine (10-40 mg/kg BW/3 times weekly) for the first time were monitored for detection of audiovisual toxicity.', select the correct biomedical concept corresponding to 'desferrioxamine'. Answer using one of the provided options. | <Options>: A: desferriferrithiocin
B: desferriferricrocin (aka desferri-ferricrocin)
C: zinc-desferrioxamine
D: n-hydroxydesferrioxamine b
E: desferrioxamine e
F: desferioximine (aka deferoxamine)
G: deferrioxamine e
H: cu(ii)-desferrioxamine (aka copper-desferal complex)
I: n-desferriferrichrome
J: mangan-desferrioxamin
K: None of the above. | F |
<Instruct>: Given the context 'Desferrioxamine withdrawal resulted in a complete recovery of visual function in 1 patient and partial recovery in 3, and a complete reversal of hearing loss in 3 patients and partial recovery in 3.', select the correct biomedical concept corresponding to 'desferrioxamine'. Answer using one of the provided options. | <Options>: A: n-hydroxydesferrioxamine b
B: zinc-desferrioxamine
C: n-desferriferrichrome
D: cu(ii)-desferrioxamine (aka copper-desferal complex)
E: mangan-desferrioxamin
F: desferrioxamine b (aka deferoxamine)
G: desferrioxamine e
H: deferrioxamine e
I: desferriferricrocin (aka desferri-ferricrocin)
J: desferriferrithiocin
K: None of the above. | F |
<Instruct>: Given the context 'This toxicity appeared in patients receiving the higher doses of desferrioxamine or coincided with the normalization of ferritin or aluminium serum levels.', select the correct biomedical concept corresponding to 'desferrioxamine'. Answer using one of the provided options. | <Options>: A: desferrioxamine e
B: desferrioxamine b mesylate (aka deferoxamine)
C: cu(ii)-desferrioxamine (aka copper-desferal complex)
D: desferri-ferricrocin
E: zinc-desferrioxamine
F: desferriferrithiocin
G: mangan-desferrioxamin
H: n-hydroxydesferrioxamine b
I: n-desferriferrichrome
J: deferrioxamine e
K: None of the above. | B |
<Instruct>: Given the context 'The data indicate that audiovisual toxicity is not an infrequent complication in hemodialyzed patients receiving desferrioxamine.', select the correct biomedical concept corresponding to 'desferrioxamine'. Answer using one of the provided options. | <Options>: A: n-hydroxy-desferrioxamine b (aka n-hydroxydesferrioxamine b)
B: desferal (aka deferoxamine)
C: n-desferriferrichrome
D: mangan-desferrioxamin
E: cu(ii)-desferrioxamine (aka copper-desferal complex)
F: desferriferrithiocin
G: deferrioxamine e
H: desferrioxamine e
I: desferriferricrocin (aka desferri-ferricrocin)
J: zinc-desferrioxamine
K: None of the above. | B |
<Instruct>: Given the context 'Myasthenia gravis presenting as weakness after magnesium administration.', select the correct biomedical concept corresponding to 'magnesium'. Answer using one of the provided options. | <Options>: A: magnesite (aka magnesium carbonate)
B: chloride, magnesium (aka magnesium chloride)
C: magnesium-25
D: magnesium compounds
E: bis(glycinato)magnesium (aka magnesium diglycinate)
F: magnesium diasporal (aka levulinic acid)
G: magnesium phosphate
H: magnesium-30
I: magnesium
J: magnesium oxide (mgo) (aka magnesium oxide)
K: None of the above. | I |
<Instruct>: Given the context 'We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia.', select the correct biomedical concept corresponding to 'magnesium'. Answer using one of the provided options. | <Options>: A: magnesium alba
B: magnesium-30
C: bis(glycinato)magnesium (aka magnesium diglycinate)
D: magnesium phosphate
E: magnesia (aka magnesium oxide)
F: magnesium chloride (mgcl2) (aka magnesium chloride)
G: magnesium compounds
H: magnesium-25
I: magnesium
J: manganese
K: None of the above. | I |
<Instruct>: Given the context 'The serum magnesium concentration was 3.0 mEq/L, which is usually well tolerated.', select the correct biomedical concept corresponding to 'magnesium'. Answer using one of the provided options. | <Options>: A: bis(glycinato)magnesium (aka magnesium diglycinate)
B: magnesium
C: magnesium-28
D: chloride, magnesium (aka magnesium chloride)
E: oxide, magnesium (aka magnesium oxide)
F: magnesium alba
G: magnesium-25
H: manganese
I: magnesium-30
J: magnesite (mg(co3)) (aka magnesium carbonate)
K: None of the above. | B |
<Instruct>: Given the context 'The magnesium was stopped and she recovered over a few days.', select the correct biomedical concept corresponding to 'magnesium'. Answer using one of the provided options. | <Options>: A: magnesium phosphate
B: magnesium
C: magnesium alba
D: magnesium-30
E: magnesium-28
F: chloride, magnesium (aka magnesium chloride)
G: magnesite (mg(co3)) (aka magnesium carbonate)
H: magnesium compounds
I: bis(glycinato)magnesium (aka magnesium diglycinate)
J: magnesia (aka magnesium oxide)
K: None of the above. | B |
<Instruct>: Given the context 'Her acetylcholine receptor antibody level was markedly elevated.', select the correct biomedical concept corresponding to 'acetylcholine'. Answer using one of the provided options. | <Options>: A: acetylcholine mustard
B: acetylethylcholine (aka acetylmonoethylcholine)
C: acetylcholine agent (aka cholinergic agents)
D: alpha-methylcholine acetate (aka alpha-methylcholine)
E: agonists, acetylcholine (aka cholinergic agonists)
F: bromide, acetylcholine (aka acetylcholine)
G: None of the above. | F |
<Instruct>: Given the context 'Although paralysis after magnesium administration has been described in patients with known myasthenia gravis, it has not previously been reported to be the initial or only manifestation of the disease.', select the correct biomedical concept corresponding to 'magnesium'. Answer using one of the provided options. | <Options>: A: magnesium alba
B: magnesium phosphate
C: magnesium chloride (mgcl2) (aka magnesium chloride)
D: manganese
E: magnesium-25
F: magnesite (aka magnesium carbonate)
G: magnesium
H: magnesium diasporal (aka levulinic acid)
I: magnesium-30
J: bis(glycinato)magnesium (aka magnesium diglycinate)
K: None of the above. | G |
<Instruct>: Given the context 'Patients who are unusually sensitive to the neuromuscular effects of magnesium should be suspected of having an underlying disorder of neuromuscular transmission.', select the correct biomedical concept corresponding to 'magnesium'. Answer using one of the provided options. | <Options>: A: magnesium chloride (mgcl2) (aka magnesium chloride)
B: magnesite (aka magnesium carbonate)
C: magnesium-30
D: magnesium-25
E: magnesium phosphate
F: magnesium alba
G: magnesium diasporal (aka levulinic acid)
H: manganese
I: magnesium
J: bis(glycinato)magnesium (aka magnesium diglycinate)
K: None of the above. | I |
<Instruct>: Given the context 'Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide.', select the correct biomedical concept corresponding to 'chloroacetaldehyde'. Answer using one of the provided options. | <Options>: A: lactaldehyde
B: p-chlorobenzaldehyde (aka 4-chlorobenzaldehyde)
C: acetylformaldehyde (aka pyruvaldehyde)
D: malealdehyde
E: 2-chlorobenzaldehyde
F: 3-chlorolactaldehyde, (+-)-isomer (aka 3-chlorolactaldehyde)
G: 3-chloro-anisaldehyde (aka 3-chloroanisaldehyde)
H: methoxyacetaldehyde (aka 2-methoxyacetaldehyde)
I: chloroacetaldehyde
J: dichloroacetaldehyde
K: None of the above. | I |
<Instruct>: Given the context 'Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide.', select the correct biomedical concept corresponding to 'cyclophosphamide'. Answer using one of the provided options. | <Options>: A: cyclophosphamide-mustard (aka aldophosphamide)
B: 2h-1,3,2-oxazaphosphorin-4-ol, 3-(2-chloroethyl)-2-((2-chloroethyl)amino)tetrahydro-, 2-oxide (aka 4-hydroxyifosfamide)
C: cytophosphane (aka cyclophosphamide)
D: 2h-1,3,2-oxazaphosphorin-2-amine, n,3-bis(2-chloroethyl)tetrahydro-, 2-oxide (aka ifosfamide)
E: trans-5-chlorocyclophosphamide (aka 5-chlorocyclophosphamide)
F: 2h-1,3,2-oxazaphosphorin-2-amine, n,n-bis(2-chloroethyl)tetrahydro-3-hydroxy-, 2-oxide (aka 3-hydroxycyclophosphamide)
G: 2h-1,3,2-oxazaphosphorin-2-amine, n,n-bis(2-chloroethyl)-5,6-dihydro-, 2-oxide (aka iminophosphamide)
H: carboxycyclophosphamide (aka carboxyphosphamide)
I: d4-cyclophosphamide
J: 4-hydroxyperoxy-cyclophosphamide (aka 4-hydroxyperoxycyclophosphamide)
K: None of the above. | C |
<Instruct>: Given the context 'Chloroacetaldehyde and its contribution to urotoxicity during treatment with cyclophosphamide or ifosfamide.', select the correct biomedical concept corresponding to 'ifosfamide'. Answer using one of the provided options. | <Options>: A: ifosforamide mustard (aka isophosphamide mustard)
B: 4-hydroxyifosfamide
C: 2h-1,3,2-oxazaphosphorin-2-amine, n,n-bis(2-chloroethyl)tetrahydro-3-hydroxy-, 2-oxide (aka 3-hydroxycyclophosphamide)
D: glucosyl-ifosfamide mustard (aka beta-d-glucosylisophosphoramide mustard)
E: 2h-1,3,2-oxazaphosphorin-2-amine, n,n-bis(2-chloroethyl)-5,6-dihydro-, 2-oxide (aka iminophosphamide)
F: isofosfamide (aka ifosfamide)
G: ifosfamide bromide mustard (aka isophosphamide bromide mustard)
H: iodocyclophosphamide
I: None of the above. | F |
<Instruct>: Given the context 'Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis.', select the correct biomedical concept corresponding to 'chloroacetaldehyde'. Answer using one of the provided options. | <Options>: A: propiolaldehyde
B: 3-chloro-anisaldehyde (aka 3-chloroanisaldehyde)
C: dichloroacetaldehyde
D: lactaldehyde
E: p-chlorobenzaldehyde (aka 4-chlorobenzaldehyde)
F: glycolaldehyde
G: methoxyacetaldehyde (aka 2-methoxyacetaldehyde)
H: chloroacetaldehyde hydrate (aka chloroacetaldehyde)
I: malealdehyde
J: 2-chlorobenzaldehyde
K: None of the above. | H |
<Instruct>: Given the context 'Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis.', select the correct biomedical concept corresponding to 'caa'. Answer using one of the provided options. | <Options>: A: caapv (aka benzyloxycarbonylalanyl-alanyl-prolyl-valine-trifluoromethyl ketone)
B: ace regimen (aka ace protocol 2)
C: cara protocol
D: ace protocol 1
E: ceca protocol
F: caaaq (aka 6-(n-carbobenzoxy-alanyl-alanyl-alanylamido)quinoline)
G: amyloid ad-ap (aka amyloid beta-peptides)
H: cac protocol
I: cag regimen (aka cag protocol)
J: cca protocol
K: None of the above. | K |
<Instruct>: Given the context 'Based on clinical data, indicating that chloroacetaldehyde (CAA) is an important metabolite of oxazaphosphorine cytostatics, an experimental study was carried out in order to elucidate the role of CAA in the development of hemorrhagic cystitis.', select the correct biomedical concept corresponding to 'caa'. Answer using one of the provided options. | <Options>: A: ad-ap, amyloid (aka amyloid beta-peptides)
B: cac protocol
C: camca (aka carbobenzoxyargininamide-7-yl-4-methylcoumarin)
D: caatrp (aka cyclo-acetoacetyl-l-tryptophan)
E: ace protocol 1
F: cag protocol
G: caapv (aka benzyloxycarbonylalanyl-alanyl-prolyl-valine-trifluoromethyl ketone)
H: cara protocol
I: ace regimen (aka ace protocol 2)
J: ceca protocol
K: None of the above. | K |
<Instruct>: Given the context 'The data demonstrate that CAA after i.v. administration does not contribute to bladder damage.', select the correct biomedical concept corresponding to 'caa'. Answer using one of the provided options. | <Options>: A: ceca protocol
B: caatrp (aka cyclo-acetoacetyl-l-tryptophan)
C: maaac (aka n-(2-methoxy-6-azidoacridin-9-yl)-n'-(4-azidobenzoyl)cystamine)
D: ace regimen (aka ace protocol 2)
E: caaaq (aka 6-(n-carbobenzoxy-alanyl-alanyl-alanylamido)quinoline)
F: cca protocol
G: ace protocol 1
H: cac protocol
I: cara protocol
J: camca (aka carbobenzoxyargininamide-7-yl-4-methylcoumarin)
K: None of the above. | K |
<Instruct>: Given the context 'When instilled directly into the bladder, CAA exerts urotoxic effects, it is, however, susceptible to detoxification with mesna.', select the correct biomedical concept corresponding to 'caa'. Answer using one of the provided options. | <Options>: A: caapv (aka benzyloxycarbonylalanyl-alanyl-prolyl-valine-trifluoromethyl ketone)
B: caaaq (aka 6-(n-carbobenzoxy-alanyl-alanyl-alanylamido)quinoline)
C: caatrp (aka cyclo-acetoacetyl-l-tryptophan)
D: ceca protocol
E: beta amyloid (aka amyloid beta-peptides)
F: cara protocol
G: ca protocol (aka ac protocol)
H: ace protocol 1
I: maaac (aka n-(2-methoxy-6-azidoacridin-9-yl)-n'-(4-azidobenzoyl)cystamine)
J: cca protocol
K: None of the above. | K |
<Instruct>: Given the context 'When instilled directly into the bladder, CAA exerts urotoxic effects, it is, however, susceptible to detoxification with mesna.', select the correct biomedical concept corresponding to 'mesna'. Answer using one of the provided options. | <Options>: A: mes-acr (aka 9-mesityl-10-methylacridinium)
B: mesmar
C: mesylate (aka mesylates)
D: mesc thiol (aka n-(2-mercaptoethyl)spermine 5-carboxamide)
E: mes cpd (aka mono-2-(methacryloyloxy)ethyl succinate)
F: mesna cell (aka mesna)
G: mesihc (aka 2-methoxy-sila-hexocyclium)
H: mesna-albumin (aka 2-mercaptoethanesulfonic acid albumin)
I: mes compound (aka 2-(n-morpholino)ethanesulfonic acid)
J: mes(o)spn (aka methanesulfinothioic acid s-1-propenyl ester)
K: None of the above. | F |
<Instruct>: Given the context 'Twenty common migraine patients received a one sided frontotemporal application of nitroglycerin (10 patients) or placebo ointment (10 patients) in a double blind study.', select the correct biomedical concept corresponding to 'nitroglycerin'. Answer using one of the provided options. | <Options>: A: glycerin-1-nitrate (aka glycerol-1-nitrate)
B: glyceryl dinitrate (aka dinitroglycerol)
C: nitropress (aka nitroprusside)
D: triethanolamine trinitrate (aka trolnitrate)
E: pentaerythrityl trinitrate (aka pentrinitrol)
F: trinitrate, glyceryl (aka nitroglycerin)
G: None of the above. | F |
<Instruct>: Given the context 'Early onset migraine attacks were induced by nitroglycerin in seven out of 10 patients versus no patient in the placebo group.', select the correct biomedical concept corresponding to 'nitroglycerin'. Answer using one of the provided options. | <Options>: A: nitropress (aka nitroprusside)
B: glycerin-1-nitrate (aka glycerol-1-nitrate)
C: nitroglyn (aka nitroglycerin)
D: pentaerythrityl trinitrate (aka pentrinitrol)
E: 1,2-glyceryl dinitrate (aka dinitroglycerol)
F: triethanolamine trinitrate (aka trolnitrate)
G: None of the above. | C |
<Instruct>: Given the context 'Subsequently 20 migraine patients, who developed an early onset attack with frontotemporal nitroglycerin, received the drug in a second induction test at other body areas.', select the correct biomedical concept corresponding to 'nitroglycerin'. Answer using one of the provided options. | <Options>: A: glyceryl-1,3-dinitrate (aka dinitroglycerol)
B: trinitrate, glyceryl (aka nitroglycerin)
C: 2,2',2''- nitrilotrisethanol, trinitrate (ester) (aka trolnitrate)
D: pentaerythrityl trinitrate (aka pentrinitrol)
E: glycerin-1-nitrate (aka glycerol-1-nitrate)
F: nitropress (aka nitroprusside)
G: None of the above. | B |
<Instruct>: Given the context 'Thus the migraine-inducing effect of nitroglycerin seems to depend on direct stimulation of the habitual site of pain, suggesting that the frontotemporal region is of crucial importance in the development of a migraine crisis.', select the correct biomedical concept corresponding to 'nitroglycerin'. Answer using one of the provided options. | <Options>: A: nitropress (aka nitroprusside)
B: trinitrate, glyceryl (aka nitroglycerin)
C: glycerin-1-nitrate (aka glycerol-1-nitrate)
D: 2,2',2''- nitrilotrisethanol, trinitrate (ester) (aka trolnitrate)
E: pentaerythrityl trinitrate (aka pentrinitrol)
F: 1,2-glyceryl dinitrate (aka dinitroglycerol)
G: None of the above. | B |
<Instruct>: Given the context 'Clotiazepam-induced acute hepatitis.', select the correct biomedical concept corresponding to 'clotiazepam'. Answer using one of the provided options. | <Options>: A: 7-chloro-2,3-dihydro-n-methyl-2-oxo-5- phenyl-lh-1-benzodiazepin-1-acetamide (aka ro 5-5807)
B: 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro- (aka chlordesmethyldiazepam)
C: 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl- (aka 2-chlorodiazepam)
D: nordiazepam (aka nordazepam)
E: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-one (aka diazepam)
F: clotiazepam
G: 1h-1,4-benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl- (aka medazepam)
H: 1-methyl-4-carbamoyl-5-phenyl-7-chloro-1,3,4,5-tetrahydro-2h-1,4-benzodiazepine-2-one (aka uxepam)
I: 7 chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-3-(morpholino)methylene-2h-1,4-benzodiazepin-2-one (aka ax-a411-bs)
J: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one (aka lormetazepam)
K: None of the above. | F |
<Instruct>: Given the context 'We report the case of a patient who developed acute hepatitis with extensive hepatocellular necrosis, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative.', select the correct biomedical concept corresponding to 'clotiazepam'. Answer using one of the provided options. | <Options>: A: 4h-1,4-benzodiazepine-4-carboxamide, 7-chloro-1,2,3,5-tetrahydro-1-methyl-2-oxo-5-phenyl-, (+-)- (aka 4-carbamoyl-4,5-dihydrodiazepam)
B: 7 chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-3-(morpholino)methylene-2h-1,4-benzodiazepin-2-one (aka ax-a411-bs)
C: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl- (aka nordazepam)
D: 1h-1,4-benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl- (aka medazepam)
E: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one (aka lormetazepam)
F: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-one (aka diazepam)
G: 7-chloro-2,3-dihydro-n-methyl-2-oxo-5- phenyl-lh-1-benzodiazepin-1-acetamide (aka ro 5-5807)
H: 7-chloro 5-(2-chlorophenyl)-1,3-dihydro-2h-(1,4)-benzodiazepine-2-thione
I: 1-phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3h-1,5-benzodiazepine (aka clobazam)
J: clotiazepam
K: None of the above. | J |
<Instruct>: Given the context 'We report the case of a patient who developed acute hepatitis with extensive hepatocellular necrosis, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative.', select the correct biomedical concept corresponding to 'thienodiazepine'. Answer using one of the provided options. | <Options>: A: rac-5-diphenylacetyl-2,2,4-trimethyl-2,3,4,5-tetrahydro-1,5-benzothiazepine
B: 5-((4-((2-methylphenyl)carbonylamino)phenyl)carbonyl)-4,10-dhydro-5h-thieno(3,2-c)(1)benzazepine
C: benzindenoazepine
D: 2,3,4,5-tetrahydro-7-methoxy-4-methyl-1,4-benzothiazepine (aka s-107 compound)
E: tetrahydrodaidzein
F: thienodiazepine substance
G: kenazepine
H: 1,5-benzothiazepine
I: 3,4,5,6-tetrahydroazepine (aka 3,4,5,6-tetrahydro-2h-azepine)
J: 5-(3-(2-(3-methylphenoxy)ethylamine)propionyl)-2,3,4,5-tetrahydro-1,5-benzothiazepine (aka kt2 230)
K: None of the above. | F |
<Instruct>: Given the context 'Clotiazepam withdrawal was followed by prompt recovery.', select the correct biomedical concept corresponding to 'clotiazepam'. Answer using one of the provided options. | <Options>: A: 1-methyl-4-carbamoyl-5-phenyl-7-chloro-1,3,4,5-tetrahydro-2h-1,4-benzodiazepine-2-one (aka uxepam)
B: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-one (aka diazepam)
C: 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl- (aka 2-chlorodiazepam)
D: 2h-1,4-benzodiazepin-2-one, 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro- (aka flurazepam)
E: 7-chloro-5-(2-chlorophenyl) 1,3-dihydro-2h-1,4-benzodiazepin-2-one (aka chlordesmethyldiazepam)
F: camazepam
G: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl- (aka nordazepam)
H: 4h-1,4-benzodiazepine-4-carboxamide, 7-chloro-1,2,3,5-tetrahydro-1-methyl-2-oxo-5-phenyl-, (+-)- (aka 4-carbamoyl-4,5-dihydrodiazepam)
I: 7 chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-3-(morpholino)methylene-2h-1,4-benzodiazepin-2-one (aka ax-a411-bs)
J: clotiazepam
K: None of the above. | J |
<Instruct>: Given the context 'The administration of several benzodiazepines, chemically related to clotiazepam, did not interfere with recovery and did not induce any relapse of hepatitis.', select the correct biomedical concept corresponding to 'benzodiazepines'. Answer using one of the provided options. | <Options>: A: desmethylmedazepam
B: d-n-benzodiazepine-dione (aka 7,8-dichloro-6-nitro-1h-1,5-benzodiazepine-2,4-(3h,5h)-dione)
C: 1,4-diazepane
D: 1,4-benzodiazepine-2,5-dione (aka bz-423)
E: 1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepine-2-one (aka bda 250)
F: benzodiazepinones
G: benzodiazepines
H: 4,5-dihydro-2,3-dimethyl-4-phenyl-3h-1,3-benzodiazepine
I: n-desmethylquazepam
J: 1,5-benzodiazepin-2-one
K: None of the above. | G |
<Instruct>: Given the context 'The administration of several benzodiazepines, chemically related to clotiazepam, did not interfere with recovery and did not induce any relapse of hepatitis.', select the correct biomedical concept corresponding to 'clotiazepam'. Answer using one of the provided options. | <Options>: A: 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro- (aka chlordesmethyldiazepam)
B: 1-methyl-4-carbamoyl-5-phenyl-7-chloro-1,3,4,5-tetrahydro-2h-1,4-benzodiazepine-2-one (aka uxepam)
C: 2h-1,4-benzodiazepin-2-one, 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro- (aka flurazepam)
D: 7 chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-3-(morpholino)methylene-2h-1,4-benzodiazepin-2-one (aka ax-a411-bs)
E: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-phenyl- (aka nordazepam)
F: clotiazepam
G: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-one (aka diazepam)
H: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one (aka lormetazepam)
I: 7-chloro 5-(2-chlorophenyl)-1,3-dihydro-2h-(1,4)-benzodiazepine-2-thione
J: 1h-1,4-benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl- (aka medazepam)
K: None of the above. | F |
<Instruct>: Given the context 'This observation shows that clotiazepam can induce acute hepatitis and suggests that there is no cross hepatotoxicity between clotiazepam and several benzodiazepines.', select the correct biomedical concept corresponding to 'clotiazepam'. Answer using one of the provided options. | <Options>: A: 1-methyl-4-carbamoyl-5-phenyl-7-chloro-1,3,4,5-tetrahydro-2h-1,4-benzodiazepine-2-one (aka uxepam)
B: 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2h-1,4-benzodiazepin-2-one (aka diazepam)
C: clotiazepam
D: 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro- (aka chlordesmethyldiazepam)
E: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one (aka lormetazepam)
F: carbamic acid, dimethyl-, 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl ester (aka camazepam)
G: 2h-1,4-benzodiazepin-2-one, 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro- (aka flurazepam)
H: 7 chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl-3-(morpholino)methylene-2h-1,4-benzodiazepin-2-one (aka ax-a411-bs)
I: 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 7-chloro-1-methyl-5-phenyl- (aka clobazam)
J: 4h-1,4-benzodiazepine-4-carboxamide, 7-chloro-1,2,3,5-tetrahydro-1-methyl-2-oxo-5-phenyl-, (+-)- (aka 4-carbamoyl-4,5-dihydrodiazepam)
K: None of the above. | C |
<Instruct>: Given the context 'This observation shows that clotiazepam can induce acute hepatitis and suggests that there is no cross hepatotoxicity between clotiazepam and several benzodiazepines.', select the correct biomedical concept corresponding to 'clotiazepam'. Answer using one of the provided options. | <Options>: A: 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1-methyl-2h-1,4-benzodiazepin-2-one (aka lormetazepam)
B: 2'-chloronordiazepam (aka chlordesmethyldiazepam)
C: 1-phenyl-5-methyl-8-chloro-1,2,4,5- tetrahydro-2,4-diketo-3h-1,5-benzodiazepine (aka clobazam)
D: 1h-1,4-benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl- (aka medazepam)
E: clotiazepam
F: 2h-1,4-benzodiazepin-2-one, 7-chloro-1-(2-(diethylamino)ethyl)-5-(2-fluorophenyl)-1,3-dihydro- (aka flurazepam)
G: 4h-1,4-benzodiazepine-4-carboxamide, 7-chloro-1,2,3,5-tetrahydro-1-methyl-2-oxo-5-phenyl-, (+-)- (aka 4-carbamoyl-4,5-dihydrodiazepam)
H: nordiazepam (aka nordazepam)
I: 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl- (aka 2-chlorodiazepam)
J: 1-methyl-4-carbamoyl-5-phenyl-7-chloro-1,3,4,5-tetrahydro-2h-1,4-benzodiazepine-2-one (aka uxepam)
K: None of the above. | E |
<Instruct>: Given the context 'This observation shows that clotiazepam can induce acute hepatitis and suggests that there is no cross hepatotoxicity between clotiazepam and several benzodiazepines.', select the correct biomedical concept corresponding to 'benzodiazepines'. Answer using one of the provided options. | <Options>: A: benzodiazepine (aka benzodiazepines)
B: 1,4-benzodiazepine-2,5-dione (aka bz-423)
C: triazolo(4,3-d)benzodiazepine
D: 4,5-dihydro-2,3-dimethyl-4-phenyl-3h-1,3-benzodiazepine
E: desmethylmedazepam
F: nordazepam
G: n-desmethylquazepam
H: benzopyrano(4,3-c)-1,5-benzodiazepine
I: 1,5-benzodiazepin-2-one
J: benzodiazepinones
K: None of the above. | A |
<Instruct>: Given the context 'Arterial hypertension as a complication of prolonged ketoconazole treatment.', select the correct biomedical concept corresponding to 'ketoconazole'. Answer using one of the provided options. | <Options>: A: ketoconazole
B: ketoscilium (aka fentonium)
C: ketoace (aka compound 20)
D: azaconazole
E: ketostix (aka nitroprusside)
F: ketocef (aka cefuroxime)
G: ketonox (aka methyl ethyl ketone peroxide)
H: ketogin (aka ketobemidone, n,n-dimethyl-3,3-diphenyl-1-methylallylamine drug combination)
I: ketothiazole (aka alpha-ketothiazole)
J: 4-ketoniridazole
K: None of the above. | A |
<Instruct>: Given the context 'Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained hypertension.', select the correct biomedical concept corresponding to 'ketoconazole'. Answer using one of the provided options. | <Options>: A: ketoconazole
B: ketogin (aka ketobemidone, n,n-dimethyl-3,3-diphenyl-1-methylallylamine drug combination)
C: ketocef (aka cefuroxime)
D: oleoylketoconazole (aka ketoconazole oleate)
E: ketocyclazocine (aka ketazocine)
F: azaconazole
G: ketoscilium (aka fentonium)
H: 5-ketoclomazone
I: oxyconazole (aka oxiconazole)
J: ketostix (aka nitroprusside)
K: None of the above. | A |
<Instruct>: Given the context 'In both cases normal plasma and urinary free cortisol levels had been achieved following ketoconazole therapy, yet continuous blood pressure monitoring demonstrated hypertension 31 (patient 1) and 52 weeks (patient 2) after treatment.', select the correct biomedical concept corresponding to 'cortisol'. Answer using one of the provided options. | <Options>: A: cortisol-17 acid
B: pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (+-)- (aka timodine)
C: 5-dihydrocortisone
D: hah-cortisol (aka heparin adipic hydrazide-cortisol)
E: a-hyrocort (aka hydrocortisone hemisuccinate)
F: pregn-4-ene-3,20-dione, 11,18,21-trihydroxy-, (11beta)- (aka 18-hydroxycorticosterone)
G: hydrocortisone, (11 alpha)-isomer (aka hydrocortisone)
H: pregn-4-en-3-one, 11,20,21-trihydroxy-, (11beta)- (aka 20-dihydrocorticosterone)
I: 20-dihydrocortisone (aka 4-pregnene-17 alpha,20 beta,21-triol-3,11-dione)
J: tetrahydrocortisone
K: None of the above. | G |
<Instruct>: Given the context 'In both cases normal plasma and urinary free cortisol levels had been achieved following ketoconazole therapy, yet continuous blood pressure monitoring demonstrated hypertension 31 (patient 1) and 52 weeks (patient 2) after treatment.', select the correct biomedical concept corresponding to 'ketoconazole'. Answer using one of the provided options. | <Options>: A: azaconazole
B: oxyconazole (aka oxiconazole)
C: ketoscilium (aka fentonium)
D: ketoconazole oleate
E: ketothiazole (aka alpha-ketothiazole)
F: 4-ketoniridazole
G: ketonox (aka methyl ethyl ketone peroxide)
H: 5-ketoclomazone
I: deacetylated ketoconazole (aka deacylketoconazole)
J: ketoconazole
K: None of the above. | J |
<Instruct>: Given the context 'In patient 1, plasma levels of deoxycorticosterone and 11-deoxycortisol were elevated.', select the correct biomedical concept corresponding to 'deoxycorticosterone'. Answer using one of the provided options. | <Options>: A: 6-hydroxy-11-deoxycorticosterone
B: 11-deoxycortisol (aka cortodoxone)
C: 21-deoxycortisone
D: desoxycorticosterone
E: 5 alpha-dihydro-11-deoxycorticosterone (aka hydroxydione)
F: 11-deoxycorticosterone-1-ene
G: 5-dihydrodeoxycorticosterone
H: 11-dehydrocorticosterone
I: 21-deoxycortisol, (9beta,10alpha,11alpha)-isomer (aka 21-deoxycortisol)
J: 3 alpha,5 beta-tetrahydrodeoxycorticosterone (aka tetrahydrodeoxycorticosterone)
K: None of the above. | D |
<Instruct>: Given the context 'In patient 1, plasma levels of deoxycorticosterone and 11-deoxycortisol were elevated.', select the correct biomedical concept corresponding to '11-deoxycortisol'. Answer using one of the provided options. | <Options>: A: tetrahydro-11-dehydrocorticosterone
B: 20-dihydro-11-deoxycortisol (aka 17,20,21-trihydroxy-4-pregnen-3-one)
C: deoxycorticosterone (aka desoxycorticosterone)
D: 5 alpha-dihydro-11-deoxycorticosterone (aka hydroxydione)
E: delta(1)-11-oxa-11-deoxycortisol
F: 11-deoxycorticosterone-1-ene
G: 11-dehydrocorticosterone
H: 11 desoxycortisone (aka cortodoxone)
I: 6-hydroxy-11-deoxycorticosterone
J: 21-deoxycortisol
K: None of the above. | H |
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