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<Instruct>: Given the context 'The development of tolerance to the muscular rigidity produced by morphine was studied in rats.', select the correct biomedical concept corresponding to 'morphine'. Answer using one of the provided options. | <Options>: A: morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy- (aka normorphine)
B: morphine dinicotinate (aka nicomorphine)
C: morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (6as-(6aalpha,7alpha,8beta,9aalpha))- (aka mersyndol)
D: morpholep (aka morfolep)
E: morphinan-3,6-diol, 7,8-didehydro-4,5-e... | H |
<Instruct>: Given the context 'Saline-pretreated controls given a test dose of morphine (20 mg/kg i.p.)', select the correct biomedical concept corresponding to 'morphine'. Answer using one of the provided options. | <Options>: A: morphine derivatives
B: morpholep (aka morfolep)
C: morphine-7,8-oxide, (5alpha,6alpha)-isomer (aka morphine-7,8-oxide)
D: morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)- (aka nalorphine)
E: morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (6as-(6aalpha,7alpha,8... | I |
<Instruct>: Given the context 'Rats treated for 11 days with morphine and withdrawn for 36-40 h showed differences in the development of tolerance: about half of the animals showed a rigidity after the test dose of morphine that was not significantly less than in the controls and were akinetic (A group).', select the c... | <Options>: A: morphine-7,8-oxide, (5alpha,6alpha)-isomer (aka morphine-7,8-oxide)
B: morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)- (aka nalorphine)
C: morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy- (aka normorphine)
D: morphine chloride (aka morphine)
E: morphinan-6-ol, 7,8-dide... | D |
<Instruct>: Given the context 'Rats treated for 11 days with morphine and withdrawn for 36-40 h showed differences in the development of tolerance: about half of the animals showed a rigidity after the test dose of morphine that was not significantly less than in the controls and were akinetic (A group).', select the c... | <Options>: A: morphines (aka morphine derivatives)
B: morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)- (aka nalorphine)
C: morphine chloride (aka morphine)
D: morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (6as-(6aalpha,7alpha,8beta,9aalpha))- (aka mersyndol)
E: morphine din... | C |
<Instruct>: Given the context 'In a further series of experiments, haloperidol (0.2 mg/kg i.p.) was used in order to block the dopaminergic activation and to estimate the real degree of the tolerance to the rigidity without any dopaminergic interference.', select the correct biomedical concept corresponding to 'haloper... | <Options>: A: n-4-tert-butyl benzyl haloperidol (aka n-(4-tert-butylbenzyl)haloperidol)
B: 4-(4-(4-chloro-3-(trifluoromethyl)phenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone (aka clofluperol)
C: reduced haloperidol (aka 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol)
D: n-n-bu... | H |
<Instruct>: Given the context 'Haloperidol enhanced the rigidity in the A group.', select the correct biomedical concept corresponding to 'haloperidol'. Answer using one of the provided options. | <Options>: A: n-(4-tert-butylbenzyl)haloperidol
B: thioketal haloperidol
C: 4-(4-(4-chloro-3-(trifluoromethyl)phenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone (aka clofluperol)
D: n-n-butyl haloperidol iodide
E: sila-haloperidol
F: haloperidol
G: reduced haloperidol (aka 4-(4-(4-chlorophenyl)-4-hydroxy-1-... | F |
<Instruct>: Given the context 'The results suggest that rigidity, which is assumed to be due to an action of morphine in the striatum, can be antagonized by another process leading to dopaminergic activation in the striatum.', select the correct biomedical concept corresponding to 'morphine'. Answer using one of the pr... | <Options>: A: n methylmorphine (aka codeine)
B: morphine-7,8-oxide, (5alpha,6alpha)-isomer (aka morphine-7,8-oxide)
C: morphine chloride (aka morphine)
D: morphidex (aka en 3231)
E: morphine derivatives
F: morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy- (aka normorphine)
G: morphinan-3,6-diol, 7,8-didehydro-4,5-... | C |
<Instruct>: Given the context 'Compression neuropathy of the radial nerve due to pentazocine-induced fibrous myopathy.', select the correct biomedical concept corresponding to 'pentazocine'. Answer using one of the provided options. | <Options>: A: 1-benzazocin-8-ol, 2-phenyl- (aka hypodematine)
B: lactate, pentazocine (aka pentazocine)
C: phenethylazocine (aka phenazocine)
D: 1,2,3,4,5,6-hexahydro-3,11-dimethyl-2,6-methano- 3-benzazocin-8-ol (aka 2,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphan)
E: bunazocine (aka bunazosin)
F: apo-terazosin (aka ter... | B |
<Instruct>: Given the context 'Fibrous myopathy is a common, well-known side effect of repeated pentazocine injection.', select the correct biomedical concept corresponding to 'pentazocine'. Answer using one of the provided options. | <Options>: A: quadazocine
B: bunazocine (aka bunazosin)
C: 1,2,3,4,5,6-hexahydro-3,11-dimethyl-2,6-methano- 3-benzazocin-8-ol (aka 2,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphan)
D: hydrochloride, pentazocine (aka pentazocine)
E: phenazocine
F: zenazocine
G: 1-benzazocin-8-ol, 2-phenyl- (aka hypodematine)
H: tonazocine... | D |
<Instruct>: Given the context 'However, compression neuropathy due to fibrotic muscle affected by pentazocine-induced myopathy has not previously been reported.', select the correct biomedical concept corresponding to 'pentazocine'. Answer using one of the provided options. | <Options>: A: pentazocine glucuronide
B: bunazocine (aka bunazosin)
C: zenazocine
D: 1,2,3,4,5,6-hexahydro-3,11-dimethyl-2,6-methano- 3-benzazocin-8-ol (aka 2,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphan)
E: lactate, pentazocine (aka pentazocine)
F: tonazocine
G: 1-benzazocin-8-ol, 2-phenyl- (aka hypodematine)
H: phene... | E |
<Instruct>: Given the context 'In a 37-year-old woman with documented pentazocine-induced fibrous myopathy of triceps and deltoid muscles bilaterally and a three-week history of right wrist drop, electrodiagnostic examination showed a severe but partial lesion of the right radial nerve distal to the branches to the tri... | <Options>: A: phenethylazocine (aka phenazocine)
B: tonazocine
C: zenazocine
D: pentazocine
E: quadazocine
F: 1-benzazocin-8-ol, 2-phenyl- (aka hypodematine)
G: terazosin hexal (aka terazosin)
H: pentazocine glucuronide
I: 1,2,3,4,5,6-hexahydro-3,11-dimethyl-2,6-methano- 3-benzazocin-8-ol (aka 2,9 alpha-dimethyl-2'-hyd... | D |
<Instruct>: Given the context 'Recurrent reversible acute renal failure from amphotericin.', select the correct biomedical concept corresponding to 'amphotericin'. Answer using one of the provided options. | <Options>: A: amphotericin b, 5,8,9-trideoxy-7,10-dihydroxy-5-oxo- (aka mycoheptin)
B: amphotericin b aglycone (aka amphoteronolide b)
C: n-fructosyl-amphotericin b (aka n-fructosylamphotericin b)
D: amphotericin b lipid complex (aka liposomal amphotericin b)
E: pame amphotericin b ester (aka n-(1-piperidinepropionyl)a... | G |
<Instruct>: Given the context 'A patient with cryptogenic cirrhosis and disseminated sporotrichosis developed acute renal failure immediately following the administration of amphotericin B on four separate occasions.', select the correct biomedical concept corresponding to 'amphotericin b'. Answer using one of the prov... | <Options>: A: amphotericin b 2-morpholinoethyl amide diaspartate
B: n-methyl-d-glucamine amphotericin b (aka amphoglucamine)
C: n-methyl-n-d-fructosyl amphotericin b methyl ester (aka n-methyl-n-fructopyranosylamphotericin b methyl ester)
D: amphotericin b, 5,8,9-trideoxy-7,10-dihydroxy-5-oxo- (aka mycoheptin)
E: pame ... | H |
<Instruct>: Given the context 'We propose that amphotericin, in the setting of reduced effective arterial volume, may activate tubuloglomerular feedback, thereby contributing to acute renal failure.', select the correct biomedical concept corresponding to 'amphotericin'. Answer using one of the provided options. | <Options>: A: amphotericin b
B: amphotericin b 2-morpholinoethyl amide diaspartate
C: amphotericin b, 5,8,9-trideoxy-7,10-dihydroxy-5-oxo- (aka mycoheptin)
D: amphotericin b-deoxycholate (aka amphotericin b, deoxycholate drug combination)
E: amphotericin b3-dimethylaminopropylamide (aka amphotericin b3-(n'-dimethylamin... | A |
<Instruct>: Given the context 'Pneumonitis with pleural and pericardial effusion and neuropathy during amiodarone therapy.', select the correct biomedical concept corresponding to 'amiodarone'. Answer using one of the provided options. | <Options>: A: di-n-desethylamiodarone
B: desethylamiodarone
C: n-desbutyldronedarone
D: amiodarone hydrochloride (aka amiodarone)
E: mono-n-desethylamiodarone
F: 2,3-dehydrodeoxamuscarone
G: malarone (aka atovaquone, proguanil drug combination)
H: des-oxo-amiodarone (aka desoxoamiodrone)
I: 4'-(methylamino)avarone
J: a... | D |
<Instruct>: Given the context 'A patient with sinuatrial disease and implanted pacemaker was treated with amiodarone (maximum dose 1000 mg, maintenance dose 800 mg daily) for 10 months, for control of supraventricular tachyarrhythmias.', select the correct biomedical concept corresponding to 'amiodarone'. Answer using ... | <Options>: A: rytmarone (aka amiodarone)
B: 4'-(methylamino)avarone
C: di-n-desethylamiodarone
D: n-desethylamiodarone (aka desethylamiodarone)
E: de-ketoamiodarone (aka desoxoamiodrone)
F: 2,3-dehydrodeoxamuscarone
G: malarone (aka atovaquone, proguanil drug combination)
H: avarone
I: n-desbutyldronedarone
J: 3-(methy... | A |
<Instruct>: Given the context 'Immediate but gradual improvement followed withdrawal of amiodarone and treatment with prednisolone.', select the correct biomedical concept corresponding to 'amiodarone'. Answer using one of the provided options. | <Options>: A: deethylamiodarone (aka desethylamiodarone)
B: 3-(methylamino)avarone
C: malarone (aka atovaquone, proguanil drug combination)
D: 2,3-dehydrodeoxamuscarone
E: avarone
F: deoxoamiodarone (aka desoxoamiodrone)
G: n-desbutyldronedarone
H: 4'-(methylamino)avarone
I: di-n-desethylamiodarone
J: rytmarone (aka am... | J |
<Instruct>: Given the context 'Immediate but gradual improvement followed withdrawal of amiodarone and treatment with prednisolone.', select the correct biomedical concept corresponding to 'prednisolone'. Answer using one of the provided options. | <Options>: A: deltasone (aka prednisone)
B: deltacortene
C: pregna-1,4-diene-3,11-dione, 17,20,21-trihydroxy- (aka 20-dihydroprednisone)
D: pred (aka prednylidene)
E: delta-cd (aka delta-cyclodextrin)
F: pred forte (aka prednisolone acetate)
G: prednisolone farnesylate
H: prednisolone 21-glucoside
I: pregna-1,4-diene-3... | I |
<Instruct>: Given the context 'Review of this and previously reported cases indicates the need for early diagnosis of amiodarone pneumonitis, immediate withdrawal of amiodarone, and prompt but continued steroid therapy to ensure full recovery.', select the correct biomedical concept corresponding to 'amiodarone'. Answe... | <Options>: A: 2,3-dehydrodeoxamuscarone
B: 4'-(methylamino)avarone
C: desethylamiodarone
D: 3-(methylamino)avarone
E: avarone
F: de-ketoamiodarone (aka desoxoamiodrone)
G: n-desbutyldronedarone
H: cordarone (aka amiodarone)
I: malarone (aka atovaquone, proguanil drug combination)
J: di-n-desethylamiodarone
K: None of t... | H |
<Instruct>: Given the context 'Review of this and previously reported cases indicates the need for early diagnosis of amiodarone pneumonitis, immediate withdrawal of amiodarone, and prompt but continued steroid therapy to ensure full recovery.', select the correct biomedical concept corresponding to 'amiodarone'. Answe... | <Options>: A: 4'-(methylamino)avarone
B: mono-n-desethylamiodarone
C: desethylamiodarone
D: 2,3-dehydrodeoxamuscarone
E: 3-(methylamino)avarone
F: malarone (aka atovaquone, proguanil drug combination)
G: avarone
H: n-desbutyldronedarone
I: rytmarone (aka amiodarone)
J: di-n-desethylamiodarone
K: None of the above. | I |
<Instruct>: Given the context 'Review of this and previously reported cases indicates the need for early diagnosis of amiodarone pneumonitis, immediate withdrawal of amiodarone, and prompt but continued steroid therapy to ensure full recovery.', select the correct biomedical concept corresponding to 'steroid'. Answer u... | <Options>: A: neuroactive steroid (aka neurosteroids)
B: steroid (aka steroids)
C: steroids, plant (aka phytosterols)
D: anabolic steroids (aka anabolic androgenic steroids)
E: corticosteroid (aka adrenal cortex hormones)
F: aeon steroid (aka androst-16-en-3-one)
G: steroid hormone, sex (aka gonadal steroid hormones)
H... | B |
<Instruct>: Given the context 'Indomethacin-induced renal insufficiency: recurrence on rechallenge.', select the correct biomedical concept corresponding to 'indomethacin'. Answer using one of the provided options. | <Options>: A: indocin (aka indomethacin)
B: no-indomethacin (aka n-acetylcysteine-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetic acid 4-(nitrooxy)butyl ester)
C: indomethacin-im (aka 1-(4-chlorobenzoyl)-3-(2-(1h-imidazol-1-yl)-2-oxoethyl)-5-methoxy-2-methyl-1h-indole)
D: desmethyl-indomethacin (aka 5-hydroxy... | A |
<Instruct>: Given the context 'We have reported a case of acute oliguric renal failure with hyperkalemia in a patient with cirrhosis, ascites, and cor pulmonale after indomethacin therapy.', select the correct biomedical concept corresponding to 'indomethacin'. Answer using one of the provided options. | <Options>: A: indomethacin triethylene ester
B: desmethyl-indomethacin (aka 5-hydroxyindomethacin)
C: no-indomethacin (aka n-acetylcysteine-1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1h-indole-3-acetic acid 4-(nitrooxy)butyl ester)
D: (des-4-chlorobenzoyl)indomethacin (aka 5-methoxy-methylindoleacetic acid)
E: indomethacin... | I |
<Instruct>: Given the context 'Prompt restoration of renal function followed drug withdrawal, while re-exposure to a single dose of indomethacin caused recurrence of acute reversible oliguria.', select the correct biomedical concept corresponding to 'indomethacin'. Answer using one of the provided options. | <Options>: A: indomethacin-im (aka 1-(4-chlorobenzoyl)-3-(2-(1h-imidazol-1-yl)-2-oxoethyl)-5-methoxy-2-methyl-1h-indole)
B: 1h-indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-(dimethylamino)-2-methyl- (aka 1-(4-chlorobenzoyl)-5-dimethylamino-2-methylindole acetic acid)
C: indometacin (aka indomethacin)
D: indomethacin ethy... | C |
<Instruct>: Given the context 'Our case supports the hypothesis that endogenous renal prostaglandins play a role in the maintenance of renal blood flow when circulating plasma volume is diminished.', select the correct biomedical concept corresponding to 'prostaglandins'. Answer using one of the provided options. | <Options>: A: pgg (aka prostaglandins g)
B: prostaglandins f
C: prostaglandins i
D: analogues, prostaglandin a (aka prostaglandins a, synthetic)
E: prostaglandin analogs (aka prostaglandins, synthetic)
F: prostaglandins h
G: prostanoids (aka prostaglandins)
H: prostaglandins a
I: None of the above. | G |
<Instruct>: Given the context 'Comparison of the subjective effects and plasma concentrations following oral and i.m. administration of flunitrazepam in volunteers.', select the correct biomedical concept corresponding to 'flunitrazepam'. Answer using one of the provided options. | <Options>: A: flurazepam
B: norflutoprazepam
C: flunitrazepam-neuraxpharm (aka flunitrazepam)
D: norflunitrazepam (aka n-desmethylflunitrazepam)
E: 3-methylflunitrazepam (aka ro 11-6893)
F: flutoprazepam
G: 7-amino-flunitrazepam (aka 7-aminoflunitrazepam)
H: None of the above. | C |
<Instruct>: Given the context 'Flunitrazepam 0.5, 1.0 or 2.0 mg was given by the oral or i.m. routes to groups of volunteers and its effects compared.', select the correct biomedical concept corresponding to 'flunitrazepam'. Answer using one of the provided options. | <Options>: A: 7-amino-flunitrazepam (aka 7-aminoflunitrazepam)
B: flunitrazepam neuraxpharm (aka flunitrazepam)
C: desmethylflunitrazepam (aka n-desmethylflunitrazepam)
D: flurazepam
E: flutoprazepam
F: norflutoprazepam
G: 3-methylflunitrazepam (aka ro 11-6893)
H: None of the above. | B |
<Instruct>: Given the context 'There was pain on i.m. injection of flunitrazepam significantly more often than with isotonic saline.', select the correct biomedical concept corresponding to 'flunitrazepam'. Answer using one of the provided options. | <Options>: A: desmethylflunitrazepam (aka n-desmethylflunitrazepam)
B: norflutoprazepam
C: 3-methylflunitrazepam (aka ro 11-6893)
D: flutoprazepam
E: flunizep von ct (aka flunitrazepam)
F: 7-aminoflunitrazepam
G: flurazepam
H: None of the above. | E |
<Instruct>: Given the context 'Changes in heart size during long-term timolol treatment after myocardial infarction.', select the correct biomedical concept corresponding to 'timolol'. Answer using one of the provided options. | <Options>: A: butyryl timolol
B: 1-((1,1-dimethylethyl)amino)-3-(2,3-dimethylphenoxy)-2-propanol (aka xibenolol)
C: adimolol
D: 1,5-naphthalenediol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)- (aka 4,8-dihydroxypropranolol)
E: canolol (aka 4-vinyl-2,6-dimethoxyphenol)
F: 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)ami... | H |
<Instruct>: Given the context 'The effect of long-term timolol treatment on heart size after myocardial infarction was evaluated by X-ray in a double-blind study including 241 patients (placebo 126, timolol 115).', select the correct biomedical concept corresponding to 'timolol'. Answer using one of the provided option... | <Options>: A: (s)-3-tert-butylamino-1-(4-(2-hydroxyethyl)phenoxy)-2-propanol (aka l 653328)
B: 2-propanol, 1-(2-bicyclo(2.2.1)hept-2-ylphenoxy)-3-((1-methylethyl)amino)- (aka bornaprolol)
C: 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)- (aka terbutaline)
D: timoptic (aka timolol)
E: 1-((1,1-dimethyl... | D |
<Instruct>: Given the context 'The effect of long-term timolol treatment on heart size after myocardial infarction was evaluated by X-ray in a double-blind study including 241 patients (placebo 126, timolol 115).', select the correct biomedical concept corresponding to 'timolol'. Answer using one of the provided option... | <Options>: A: 2-propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)- (aka penbutolol)
B: 1-((1,1-dimethylethyl)amino)-3-(2,3-dimethylphenoxy)-2-propanol (aka xibenolol)
C: (s)-1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadazol-3-yl)oxy)-2-propanol (aka timolol)
D: butofilolol, (+-)-isomer (a... | C |
<Instruct>: Given the context 'The timolol-treated patients showed a small but significant increase in heart size from baseline in contrast to a decrease in the placebo group.', select the correct biomedical concept corresponding to 'timolol'. Answer using one of the provided options. | <Options>: A: adimolol
B: butofilolol
C: canolol (aka 4-vinyl-2,6-dimethoxyphenol)
D: (s)-3-tert-butylamino-1-(4-(2-hydroxyethyl)phenoxy)-2-propanol (aka l 653328)
E: timolol butyryl ester (aka butyryl timolol)
F: timolol
G: 2-propanol, 1-(2-bicyclo(2.2.1)hept-2-ylphenoxy)-3-((1-methylethyl)amino)- (aka bornaprolol)
H:... | F |
<Instruct>: Given the context 'These differences may be caused by timolol-induced bradycardia and a compensatory increase in end-diastolic volume.', select the correct biomedical concept corresponding to 'timolol'. Answer using one of the provided options. | <Options>: A: 1,5-naphthalenediol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)- (aka 4,8-dihydroxypropranolol)
B: canolol (aka 4-vinyl-2,6-dimethoxyphenol)
C: 1-((1,1-dimethylethyl)amino)-3-(2,3-dimethylphenoxy)-2-propanol (aka xibenolol)
D: (s)-3-tert-butylamino-1-(4-(2-hydroxyethyl)phenoxy)-2-propanol (aka l 653328... | H |
<Instruct>: Given the context 'The timolol-related increase in heart size was observed only in patients with normal and borderline heart size.', select the correct biomedical concept corresponding to 'timolol'. Answer using one of the provided options. | <Options>: A: (s)-3-tert-butylamino-1-(4-(2-hydroxyethyl)phenoxy)-2-propanol (aka l 653328)
B: adimolol
C: timolol maleate (aka timolol)
D: butofilolol, (+-)-isomer (aka butofilolol)
E: 2-propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)- (aka penbutolol)
F: canolol (aka 4-vinyl-2,6-dimethoxyphenol)
G: ti... | C |
<Instruct>: Given the context 'After re-infarction, heart size increased in the placebo group and remained unchanged in the timolol group.', select the correct biomedical concept corresponding to 'timolol'. Answer using one of the provided options. | <Options>: A: timolol butyryl ester (aka butyryl timolol)
B: 1,5-naphthalenediol, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)- (aka 4,8-dihydroxypropranolol)
C: 1,3-benzenediol, 5-(2-((1,1-dimethylethyl)amino)-1-hydroxyethyl)- (aka terbutaline)
D: 2-propanol, 1-(2-cyclopentylphenoxy)-3-((1,1-dimethylethyl)amino)- (ak... | J |
<Instruct>: Given the context 'Vitamin D3 toxicity in dairy cows.', select the correct biomedical concept corresponding to 'vitamin d3'. Answer using one of the provided options. | <Options>: A: provitamin d(3) (aka 7-dehydrocholesterol)
B: dihydroxy-vitamin d3
C: 25 hydroxyvitamin d 3 (aka calcifediol)
D: vitamin d2 (aka ergocalciferols)
E: d3 compound
F: 1,25 dihydroxyvitamin d3 (aka calcitriol)
G: previtamin d3 (aka previtamin d(3))
H: cholecalciferols (aka cholecalciferol)
I: dhdh-vitamin d3 ... | H |
<Instruct>: Given the context 'Large parenteral doses of vitamin D3 (15 to 17.5 x 10(6) IU vitamin D3) were associated with prolonged hypercalcemia, hyperphosphatemia, and large increases of vitamin D3 and its metabolites in the blood plasma of nonlactating nonpregnant and pregnant Jersey cows.', select the correct bio... | <Options>: A: d3 compound
B: previtamin d3 (aka previtamin d(3))
C: dihydroxy-vitamin d3
D: d3, 1,25-dihydroxyvitamin (aka calcitriol)
E: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
F: provitamin d(3) (aka 7-dehydrocholesterol)
G: 25-hydroxyvitamin d 3 (aka calcifediol)
H: cholecalciferol
I: vitam... | H |
<Instruct>: Given the context 'Large parenteral doses of vitamin D3 (15 to 17.5 x 10(6) IU vitamin D3) were associated with prolonged hypercalcemia, hyperphosphatemia, and large increases of vitamin D3 and its metabolites in the blood plasma of nonlactating nonpregnant and pregnant Jersey cows.', select the correct bio... | <Options>: A: provitamin d(3) (aka 7-dehydrocholesterol)
B: 9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol, (1alpha,3beta,5z,7e)- (aka calcitriol)
C: 25-hydroxyvitamin d 3 (aka calcifediol)
D: dihydroxy-vitamin d3
E: previtamin d(3)
F: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
G: d3 compound
H... | I |
<Instruct>: Given the context 'Large parenteral doses of vitamin D3 (15 to 17.5 x 10(6) IU vitamin D3) were associated with prolonged hypercalcemia, hyperphosphatemia, and large increases of vitamin D3 and its metabolites in the blood plasma of nonlactating nonpregnant and pregnant Jersey cows.', select the correct bio... | <Options>: A: 25-hydroxyvitamin d3 (aka calcifediol)
B: calciferols (aka ergocalciferols)
C: 1,25 dihydroxyvitamin d3 (aka calcitriol)
D: d3 compound
E: previtamin d3 (aka previtamin d(3))
F: vitamin d 3 (aka cholecalciferol)
G: dihydroxy-vitamin d3
H: provitamin d(3) (aka 7-dehydrocholesterol)
I: dhdh-vitamin d3 (aka ... | F |
<Instruct>: Given the context 'Calcium concentrations 1 day postpartum were higher in cows treated with vitamin D3 about 32 days prepartum (8.8 mg/100 ml) than in control cows (5.5 mg/100 ml).', select the correct biomedical concept corresponding to 'calcium'. Answer using one of the provided options. | <Options>: A: calcium carbide
B: phosphates, calcium (aka calcium phosphates)
C: calcium radioisotopes
D: calcium chloride
E: calcium-50
F: calcium-49
G: calic
H: compounds, calcium (aka calcium compounds)
I: calcium
J: calcium, dietary
K: None of the above. | I |
<Instruct>: Given the context 'Calcium concentrations 1 day postpartum were higher in cows treated with vitamin D3 about 32 days prepartum (8.8 mg/100 ml) than in control cows (5.5 mg/100 ml).', select the correct biomedical concept corresponding to 'vitamin d3'. Answer using one of the provided options. | <Options>: A: 1,25 dihydroxyvitamin d3 (aka calcitriol)
B: previtamin d3 (aka previtamin d(3))
C: cholecalciferols (aka cholecalciferol)
D: dihydroxy-vitamin d3
E: d3 compound
F: 25 hydroxyvitamin d 3 (aka calcifediol)
G: provitamin d(3) (aka 7-dehydrocholesterol)
H: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-ho... | C |
<Instruct>: Given the context 'None of the cows treated with vitamin D3 showed signs of milk fever during the peripartal period; however, 22% of the control cows developed clinical signs of milk fever during this period.', select the correct biomedical concept corresponding to 'vitamin d3'. Answer using one of the prov... | <Options>: A: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
B: calciferols (aka ergocalciferols)
C: d3 compound
D: 25 hydroxyvitamin d 3 (aka calcifediol)
E: previtamin d3 (aka previtamin d(3))
F: provitamin d(3) (aka 7-dehydrocholesterol)
G: 1,25 dihydroxyvitamin d3 (aka calcitriol)
H: cholecalcife... | H |
<Instruct>: Given the context 'Signs of vitamin D3 toxicity were not observed in nonlactating nonpregnant cows; however, pregnant cows commonly developed severe signs of vitamin D3 toxicity and 10 of 17 cows died.', select the correct biomedical concept corresponding to 'vitamin d3'. Answer using one of the provided op... | <Options>: A: provitamin d(3) (aka 7-dehydrocholesterol)
B: 25-hydroxyvitamin d 3 (aka calcifediol)
C: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
D: dihydroxy-vitamin d3
E: vitamin d2 (aka ergocalciferols)
F: previtamin d(3)
G: 1,25 dihydroxyvitamin d3 (aka calcitriol)
H: d3 compound
I: cholecalc... | I |
<Instruct>: Given the context 'Signs of vitamin D3 toxicity were not observed in nonlactating nonpregnant cows; however, pregnant cows commonly developed severe signs of vitamin D3 toxicity and 10 of 17 cows died.', select the correct biomedical concept corresponding to 'vitamin d3'. Answer using one of the provided op... | <Options>: A: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
B: vitamin d3 (aka cholecalciferol)
C: 9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol, (1alpha,3beta,5z,7e)- (aka calcitriol)
D: provitamin d(3) (aka 7-dehydrocholesterol)
E: vitamin d2 (aka ergocalciferols)
F: previtamin d3 (aka previtam... | B |
<Instruct>: Given the context 'Because of the extreme toxicity of vitamin D3 in pregnant Jersey cows and the low margin of safety between doses of vitamin D3 that prevent milk fever and doses that induce milk fever, we concluded that vitamin D3 cannot be used practically to prevent milk fever when injected several week... | <Options>: A: previtamin d3 (aka previtamin d(3))
B: vitamin d2 (aka ergocalciferols)
C: dihydroxy-vitamin d3
D: d3 compound
E: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
F: vitamin d3 (aka cholecalciferol)
G: provitamin d(3) (aka 7-dehydrocholesterol)
H: 25 hydroxyvitamin d3 (aka calcifediol)
I:... | F |
<Instruct>: Given the context 'Because of the extreme toxicity of vitamin D3 in pregnant Jersey cows and the low margin of safety between doses of vitamin D3 that prevent milk fever and doses that induce milk fever, we concluded that vitamin D3 cannot be used practically to prevent milk fever when injected several week... | <Options>: A: previtamin d3 (aka previtamin d(3))
B: vitamin d 2 (aka ergocalciferols)
C: 25 hydroxyvitamin d 3 (aka calcifediol)
D: cholecalciferol
E: dihydroxy-vitamin d3
F: d3 compound
G: provitamin d(3) (aka 7-dehydrocholesterol)
H: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
I: 1,25 dihydroxy... | D |
<Instruct>: Given the context 'Because of the extreme toxicity of vitamin D3 in pregnant Jersey cows and the low margin of safety between doses of vitamin D3 that prevent milk fever and doses that induce milk fever, we concluded that vitamin D3 cannot be used practically to prevent milk fever when injected several week... | <Options>: A: 9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol, (1alpha,3beta,5z,7e)- (aka calcitriol)
B: 25 hydroxyvitamin d3 (aka calcifediol)
C: dhdh-vitamin d3 (aka 22-dehydro-1,25-dihydroxy-24-homovitamin d3)
D: previtamin d(3)
E: vitamin d3 (aka cholecalciferol)
F: dihydroxy-vitamin d3
G: provitamin d(3) (aka 7-d... | E |
<Instruct>: Given the context 'Peripheral neuropathy due to nutritional deficiency of thiamine and riboflavin was common (10.1%) and presented mainly as sensory and sensori-motor neuropathy.', select the correct biomedical concept corresponding to 'thiamine'. Answer using one of the provided options. | <Options>: A: monophosphate, thiamine (aka thiamine monophosphate)
B: s-(beta-p-methylpropiophenone)thiamine (aka mb 3)
C: thiamine
D: vitamin bt (aka carnitine)
E: pyrophosphate, thiamine (aka thiamine pyrophosphate)
F: thiamine thiazolone
G: s-(beta-p-methoxypropiophenone)thiamine
H: thiamine disulphide (aka thiamine... | C |
<Instruct>: Given the context 'Peripheral neuropathy due to nutritional deficiency of thiamine and riboflavin was common (10.1%) and presented mainly as sensory and sensori-motor neuropathy.', select the correct biomedical concept corresponding to 'riboflavin'. Answer using one of the provided options. | <Options>: A: riboflavinal (aka vitamin b2 aldehyde)
B: cm-riboflavin (aka 3-carboxymethylriboflavin)
C: riboflavin, alpha7-hydroxy- (aka 7-hydroxymethylriboflavin)
D: riboflavin
E: riboflavin, 8-demethyl-8-mercapto- (aka 8-mercaptoriboflavin)
F: riboflavin, alpha8-((2-amino-2-carboxyethyl)thio)-, (r)- (aka s-cysteinyl... | D |
<Instruct>: Given the context 'Isoniazid was the most frequent agent in drug-induced neuropathy.', select the correct biomedical concept corresponding to 'isoniazid'. Answer using one of the provided options. | <Options>: A: cupric isoniazid (aka cupric isonicotinohydrazide)
B: nicotinic acid hydrazide
C: nicotine hydrazide
D: isoniazid methanesulfonate (aka methaniazide)
E: pyridine-2-carboxaldehyde isonicotinoyl hydrazone
F: isoniazid, pyrazinamide, rifampin drug combination
G: isoniazide 4-aminosalicylate (aka pasiniazide)... | I |
<Instruct>: Given the context 'A double-blind study of the efficacy and safety of dothiepin hydrochloride in the treatment of major depressive disorder.', select the correct biomedical concept corresponding to 'dothiepin hydrochloride'. Answer using one of the provided options. | <Options>: A: hydrochloride, doxepin (aka doxepin)
B: dothiepin
C: n,n-dimethyldibenzo(b,f)thiepin-10-methylamine (aka gp 41299)
D: piperazine, 1-dibenzo(b,f)thiepin-10-yl-4-methyl- (aka 10-(4-methylpiperazino)dibenzo(b,f)thiepin)
E: technepine
F: dibenzepin hydrochloride (aka dibenzepin)
G: dothiepin s-oxide (aka doth... | B |
<Instruct>: Given the context 'In a 6-week double-blind parallel treatment study, dothiepin and amitriptyline were compared to placebo in the treatment of 33 depressed outpatients.', select the correct biomedical concept corresponding to 'dothiepin'. Answer using one of the provided options. | <Options>: A: n,n-dimethyldibenzo(b,f)thiepin-10-methylamine (aka gp 41299)
B: dothiepin
C: dibenzo(c,e)azepine
D: 10,11-dihydro-5h-dibenzo(b,f)azepine
E: dibenzepin
F: 10-(4-methylpiperazino)dibenzo(b,f)thiepin
G: kristepin (aka clopamide, dihydroergotoxine, reserpine drug combination)
H: 5,7-dihydro-6h-dibenz-(b,d)az... | B |
<Instruct>: Given the context 'In a 6-week double-blind parallel treatment study, dothiepin and amitriptyline were compared to placebo in the treatment of 33 depressed outpatients.', select the correct biomedical concept corresponding to 'amitriptyline'. Answer using one of the provided options. | <Options>: A: n-phenylethyl amitriptyline
B: n-trimethyl-3-(5h-dibenzo-(a,d)-cyclohepten-5-yl)propylamine (aka dimethylprotriptyline)
C: nu nortriptyline (aka nortriptyline)
D: amitriptylinoxide (aka amitriptyline n-oxide)
E: amitriptylin beta (aka amitriptyline)
F: None of the above. | E |
<Instruct>: Given the context 'Dothiepin and amitriptyline were equally effective in alleviating the symptoms of depressive illness, and both were significantly superior to placebo.', select the correct biomedical concept corresponding to 'dothiepin'. Answer using one of the provided options. | <Options>: A: dothiepin s-oxide monosuccinate (aka dothiepin sulfoxide)
B: dibenzo(c,e)azepine
C: 3-(piperazinyl)-1-9h-dibenz(c,f)triazolo(4,5-a)azepin (aka pitrazepin)
D: technepine
E: 10,11-dihydro-5h-dibenzo(b,f)azepine
F: kristepin (aka clopamide, dihydroergotoxine, reserpine drug combination)
G: n,n-dimethyldibenz... | J |
<Instruct>: Given the context 'Dothiepin and amitriptyline were equally effective in alleviating the symptoms of depressive illness, and both were significantly superior to placebo.', select the correct biomedical concept corresponding to 'amitriptyline'. Answer using one of the provided options. | <Options>: A: n-phenylethyl amitriptyline
B: novo-nortriptyline (aka nortriptyline)
C: n-trimethyl-3-(5h-dibenzo-(a,d)-cyclohepten-5-yl)propylamine (aka dimethylprotriptyline)
D: desitin, amitriptylin (aka amitriptyline)
E: amitriptyline n-oxide
F: None of the above. | D |
<Instruct>: Given the context 'The overall incidence of side effects and the frequency and severity of blurred vision, dry mouth, and drowsiness were significantly less with dothiepin than with amitriptyline.', select the correct biomedical concept corresponding to 'dothiepin'. Answer using one of the provided options. | <Options>: A: n,n-dimethyldibenzo(b,f)thiepin-10-methylamine (aka gp 41299)
B: 10,11-dihydro-5h-dibenzo(b,f)azepine
C: kristepin (aka clopamide, dihydroergotoxine, reserpine drug combination)
D: hydrochloride, dothiepin (aka dothiepin)
E: piperazine, 1-dibenzo(b,f)thiepin-10-yl-4-methyl- (aka 10-(4-methylpiperazino)dib... | D |
<Instruct>: Given the context 'The overall incidence of side effects and the frequency and severity of blurred vision, dry mouth, and drowsiness were significantly less with dothiepin than with amitriptyline.', select the correct biomedical concept corresponding to 'amitriptyline'. Answer using one of the provided opti... | <Options>: A: n-phenylethyl amitriptyline
B: n-trimethyl-3-(5h-dibenzo-(a,d)-cyclohepten-5-yl)propylamine (aka dimethylprotriptyline)
C: amitriptylin desitin (aka amitriptyline)
D: amitriptylinoxide (aka amitriptyline n-oxide)
E: apo-nortriptyline (aka nortriptyline)
F: None of the above. | C |
<Instruct>: Given the context 'Dothiepin also produced fewer CNS and cardiovascular effects.', select the correct biomedical concept corresponding to 'dothiepin'. Answer using one of the provided options. | <Options>: A: dosulepin (aka dothiepin)
B: dibenzepin
C: kristepin (aka clopamide, dihydroergotoxine, reserpine drug combination)
D: 10-(4-methylpiperazino)dibenzo(b,f)thiepin
E: 5,7-dihydro-6h-dibenz-(b,d)azepin-6-one
F: n,n-dimethyldibenzo(b,f)thiepin-10-methylamine (aka gp 41299)
G: dothiepin s-oxide (aka dothiepin ... | A |
<Instruct>: Given the context 'Dothiepin thus was found to be an effective antidepressant drug associated with fewer side effects than amitriptyline in the treatment of depressed outpatients.', select the correct biomedical concept corresponding to 'dothiepin'. Answer using one of the provided options. | <Options>: A: dothistromin
B: dothiepin s-oxide (aka dothiepin sulfoxide)
C: 3-(piperazinyl)-1-9h-dibenz(c,f)triazolo(4,5-a)azepin (aka pitrazepin)
D: technepine
E: dibenzo(c,e)azepine
F: n,n-dimethyldibenzo(b,f)thiepin-10-methylamine (aka gp 41299)
G: 10,11-dihydro-5h-dibenzo(b,f)azepine
H: 10-(4-methylpiperazino)dibe... | I |
<Instruct>: Given the context 'Dothiepin thus was found to be an effective antidepressant drug associated with fewer side effects than amitriptyline in the treatment of depressed outpatients.', select the correct biomedical concept corresponding to 'antidepressant'. Answer using one of the provided options. | <Options>: A: medication, antipsychotic (aka antipsychotic agents)
B: antidepressants, atypical (aka antidepressive agents, second-generation)
C: medication, antidepressant (aka antidepressive agents)
D: antidementia agents (aka nootropic agents)
E: None of the above. | C |
<Instruct>: Given the context 'Dothiepin thus was found to be an effective antidepressant drug associated with fewer side effects than amitriptyline in the treatment of depressed outpatients.', select the correct biomedical concept corresponding to 'amitriptyline'. Answer using one of the provided options. | <Options>: A: n-trimethyl-3-(5h-dibenzo-(a,d)-cyclohepten-5-yl)propylamine (aka dimethylprotriptyline)
B: n-phenylethyl amitriptyline
C: amitriptyline n-oxide
D: amitriptyline
E: novo-nortriptyline (aka nortriptyline)
F: None of the above. | D |
<Instruct>: Given the context 'Behavioral effects of diazepam and propranolol in patients with panic disorder and agoraphobia.', select the correct biomedical concept corresponding to 'diazepam'. Answer using one of the provided options. | <Options>: A: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl- (aka oxazepam)
B: 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 7-chloro-1-methyl-5-phenyl- (aka clobazam)
C: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1h-pyrrol-2-yl)- (aka ro 5-3335)
D: diazepam
E: 2h-1,4-benzodiazepin-2-one, 7-chl... | D |
<Instruct>: Given the context 'Behavioral effects of diazepam and propranolol in patients with panic disorder and agoraphobia.', select the correct biomedical concept corresponding to 'propranolol'. Answer using one of the provided options. | <Options>: A: chloranolol (aka tobanum)
B: palmitoyl propranolol
C: propanolol (aka propranolol)
D: o-isovaleryl propranolol
E: propranolol mustard
F: propranolol laurate
G: propranolol cr
H: butyryl propranolol
I: propranolol fd
J: 2-propanol, 1-((1-methylethyl)amino)-3-(2-propylphenoxy)- (aka dihydroalprenolol)
K: No... | C |
<Instruct>: Given the context 'The effects of oral doses of diazepam (single dose of 10 mg and a median dose of 30 mg/day for 2 weeks) and propranolol (single dose of 80 mg and a median dose of 240 mg/day for 2 weeks) on psychological performance of patients with panic disorders and agoraphobia were investigated in a d... | <Options>: A: carbamic acid, dimethyl-, 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl ester (aka camazepam)
B: 2h-1,4-benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-1-methyl- (aka 2-chlorodiazepam)
C: diazepam
D: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1h-pyrrol-2-yl)-... | C |
<Instruct>: Given the context 'The effects of oral doses of diazepam (single dose of 10 mg and a median dose of 30 mg/day for 2 weeks) and propranolol (single dose of 80 mg and a median dose of 240 mg/day for 2 weeks) on psychological performance of patients with panic disorders and agoraphobia were investigated in a d... | <Options>: A: propranolol-fd (aka propranolol fd)
B: propanolol (aka propranolol)
C: propranolol laurate
D: o-isovaleryl propranolol
E: adamanolol
F: propranolol glycol
G: propranolol mustard
H: chloranolol (aka tobanum)
I: palmitoyl propranolol
J: propranolol cr
K: None of the above. | B |
<Instruct>: Given the context 'Both drugs impaired immediate free recall but the decrease was greater for diazepam than propranolol.', select the correct biomedical concept corresponding to 'diazepam'. Answer using one of the provided options. | <Options>: A: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl- (aka temazepam)
B: carbamic acid, dimethyl-, 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl ester (aka camazepam)
C: 1h-1,4-benzodiazepine, 7-chloro-2,3-dihydro-1-methyl-5-phenyl- (aka medazepam)
D: 7-chl... | D |
<Instruct>: Given the context 'Both drugs impaired immediate free recall but the decrease was greater for diazepam than propranolol.', select the correct biomedical concept corresponding to 'propranolol'. Answer using one of the provided options. | <Options>: A: propranolol glycol
B: propranolol mustard
C: adamanolol
D: dimethylpropranolol (aka pranolium)
E: propanolol (aka propranolol)
F: o-isovaleryl propranolol
G: palmitoyl propranolol
H: propranolol laurate
I: chloranolol (aka tobanum)
J: propranolol-fd (aka propranolol fd)
K: None of the above. | E |
<Instruct>: Given the context 'Patients tapped faster after propranolol than diazepam and they were more sedated after diazepam than propranolol.', select the correct biomedical concept corresponding to 'propranolol'. Answer using one of the provided options. | <Options>: A: o-isovaleryl propranolol
B: 1-isopropylamino-3-(1-naphthylamino)-2-propanol (aka bdgj)
C: 2-propanol, 1-((1-methylethyl)amino)-3-(2-propylphenoxy)- (aka dihydroalprenolol)
D: propranolol mustard
E: 2-propanol, 1-((1-methylethyl)amino)-3-(1-naphthalenyloxy)- (aka propranolol)
F: propranolol cr
G: adamanolo... | E |
<Instruct>: Given the context 'Patients tapped faster after propranolol than diazepam and they were more sedated after diazepam than propranolol.', select the correct biomedical concept corresponding to 'diazepam'. Answer using one of the provided options. | <Options>: A: carbamic acid, dimethyl-, 7-chloro-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl ester (aka camazepam)
B: 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 7-chloro-1-methyl-5-phenyl- (aka clobazam)
C: diazepam
D: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1h-pyrrol-2-yl)- (aka ro 5-3335)
E... | C |
<Instruct>: Given the context 'Patients tapped faster after propranolol than diazepam and they were more sedated after diazepam than propranolol.', select the correct biomedical concept corresponding to 'diazepam'. Answer using one of the provided options. | <Options>: A: diazepam
B: 1h-1,5-benzodiazepine-2,4(3h,5h)-dione, 7-chloro-1-methyl-5-phenyl- (aka clobazam)
C: clotiazepam
D: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl- (aka temazepam)
E: 2h-1,4-benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(1h-pyrrol-2-yl)- (aka ro 5-3335)
F: 4h-1,4-b... | A |
<Instruct>: Given the context 'Patients tapped faster after propranolol than diazepam and they were more sedated after diazepam than propranolol.', select the correct biomedical concept corresponding to 'propranolol'. Answer using one of the provided options. | <Options>: A: o-isovaleryl propranolol
B: propranolol cr
C: propranolol
D: adamanolol
E: propranolol mustard
F: butyryl propranolol
G: dimethylpropranolol (aka pranolium)
H: propranolol laurate
I: propranolol glycol
J: chloranolol (aka tobanum)
K: None of the above. | C |
<Instruct>: Given the context 'Effect of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induced epithelial proliferation in the urinary bladder and forestomach of the rat.', select the correct biomedical concept corresponding to 'aspirin'. Answer using one of the provided options. | <Options>: A: 4-(acetylamino)benzeneacetic acid
B: acetylsalicylic anhydride
C: aspirin like agent (aka anti-inflammatory agents, non-steroidal)
D: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
E: nosh-aspirin (aka 4-(3-thioxo-3h-1,2-dithiol-5-yl)phenyl 2-((4... | J |
<Instruct>: Given the context 'Effect of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induced epithelial proliferation in the urinary bladder and forestomach of the rat.', select the correct biomedical concept corresponding to 'n-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide'. Answer using one of the provided... | <Options>: A: n'-formyl-2-(5-nitrothiophen-2-yl)benzothiazole-6-carbohydrazide
B: n-4-(5-nitro-2-furyl)-2-thiazolylformamide (aka fanft)
C: 4-(5-nitro-2-furyl)thiazole
D: 1-(((5-nitro-2-furyl)methylene)amino)-1,2,4-triazole
E: 2-furanacetamide, alpha-((5-nitro-2-furanyl)methylene)- (aka furylfuramide)
F: formic acid 2-... | B |
<Instruct>: Given the context 'The co-administration of aspirin with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT) to rats resulted in a reduced incidence of FANFT-induced bladder carcinomas but a concomitant induction of forestomach tumors.', select the correct biomedical concept corresponding to 'aspirin'. An... | <Options>: A: acetylsalicylic anhydride
B: nosh-aspirin (aka 4-(3-thioxo-3h-1,2-dithiol-5-yl)phenyl 2-((4-(nitrooxy)butanoyl)oxy)benzoate)
C: 2-(acetoxymethyl)benzoic acid
D: 4-(acetylamino)benzeneacetic acid
E: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
F... | J |
<Instruct>: Given the context 'The co-administration of aspirin with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT) to rats resulted in a reduced incidence of FANFT-induced bladder carcinomas but a concomitant induction of forestomach tumors.', select the correct biomedical concept corresponding to 'n-[4-(5-nitr... | <Options>: A: 4-(5-nitro-2-furfurylidenamino)-4h-1,2,4-triazole (aka furazonal)
B: 2-furanacetamide, alpha-((5-nitro-2-thienyl)methylene)-, (z)- (aka 3-(5-nitro-2-thienyl)-2-(2-furyl)acrylamide)
C: n-(4-(5-nitro-2-furyl)-2-thiazolyl)acetamide (aka furothiazole)
D: n-(5-nitrofurfurylidene)-5-nitrofuran-2-(n'-acetyl)carb... | J |
<Instruct>: Given the context 'The co-administration of aspirin with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT) to rats resulted in a reduced incidence of FANFT-induced bladder carcinomas but a concomitant induction of forestomach tumors.', select the correct biomedical concept corresponding to 'fanft'. Answ... | <Options>: A: ara-fump (aka 5-fluorouracil arabinonucleoside 5'-phosphate)
B: anft
C: flths (aka fluorescein thiosemicarbazide)
D: fan regimen
E: fana cpd (aka 2'-deoxy-2'-fluoro-beta-d-arabinonucleic acid)
F: fansidar (aka fanasil, pyrimethamine drug combination)
G: fanapt (aka iloperidone)
H: ft005 (aka ft 005)
I: fa... | J |
<Instruct>: Given the context 'The co-administration of aspirin with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT) to rats resulted in a reduced incidence of FANFT-induced bladder carcinomas but a concomitant induction of forestomach tumors.', select the correct biomedical concept corresponding to 'fanft'. Answ... | <Options>: A: fanasil (aka sulfadoxine)
B: fana cpd (aka 2'-deoxy-2'-fluoro-beta-d-arabinonucleic acid)
C: fanapt (aka iloperidone)
D: fttaos (aka fluorotelomer thioether amido sulfonate)
E: satfpt (aka succinimidyl 2-(4-azido-2,3,5,6-tetrafluorophenyl)thiazole-4-carboxylate)
F: ara-fump (aka 5-fluorouracil arabinonucl... | G |
<Instruct>: Given the context 'An autoradiographic study was performed on male F-344 rats fed diet containing FANFT at a level of 0.2% and/or aspirin at a level of 0.5% to evaluate the effect of aspirin on the increased cell proliferation induced by FANFT in the forestomach and bladder.', select the correct biomedical ... | <Options>: A: fanasil (aka sulfadoxine)
B: faman (aka n-fluoroacetylmannosamine)
C: flths (aka fluorescein thiosemicarbazide)
D: fanft
E: flsua (aka n-2-fluorenylsuccinamic acid)
F: fefau (aka 5-(2-fluoroethyl)-2'-fluoroarabinofuranosyluracil)
G: fana cpd (aka 2'-deoxy-2'-fluoro-beta-d-arabinonucleic acid)
H: fttaos (a... | D |
<Instruct>: Given the context 'An autoradiographic study was performed on male F-344 rats fed diet containing FANFT at a level of 0.2% and/or aspirin at a level of 0.5% to evaluate the effect of aspirin on the increased cell proliferation induced by FANFT in the forestomach and bladder.', select the correct biomedical ... | <Options>: A: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
B: nosh-aspirin (aka 4-(3-thioxo-3h-1,2-dithiol-5-yl)phenyl 2-((4-(nitrooxy)butanoyl)oxy)benzoate)
C: 4-acetylbenzoic acid
D: benzoic acid, 2-(acetyloxy)- (aka aspirin)
E: 2-(acetoxymethyl)benzoic ac... | D |
<Instruct>: Given the context 'An autoradiographic study was performed on male F-344 rats fed diet containing FANFT at a level of 0.2% and/or aspirin at a level of 0.5% to evaluate the effect of aspirin on the increased cell proliferation induced by FANFT in the forestomach and bladder.', select the correct biomedical ... | <Options>: A: 2-(acetoxymethyl)benzoic acid
B: acetylsalicylsalicylic acid
C: 4-(acetylamino)benzeneacetic acid
D: aspirin
E: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
F: 2-acetoxymethylbenzoate
G: 4-acetylbenzoic acid
H: acetyl-p-aminobenzoic acid (aka a... | D |
<Instruct>: Given the context 'An autoradiographic study was performed on male F-344 rats fed diet containing FANFT at a level of 0.2% and/or aspirin at a level of 0.5% to evaluate the effect of aspirin on the increased cell proliferation induced by FANFT in the forestomach and bladder.', select the correct biomedical ... | <Options>: A: fanft
B: fansidar (aka fanasil, pyrimethamine drug combination)
C: fansimef (aka mefloquine-sulfadoxine-pyrimethamine)
D: fugan fang
E: ft005 (aka ft 005)
F: satfpt (aka succinimidyl 2-(4-azido-2,3,5,6-tetrafluorophenyl)thiazole-4-carboxylate)
G: flsua (aka n-2-fluorenylsuccinamic acid)
H: anft
I: faman (... | A |
<Instruct>: Given the context 'FANFT-induced cell proliferation in the bladder was significantly suppressed by aspirin co-administration after 4 weeks but not after 12 weeks.', select the correct biomedical concept corresponding to 'fanft'. Answer using one of the provided options. | <Options>: A: fttaos (aka fluorotelomer thioether amido sulfonate)
B: ara-fump (aka 5-fluorouracil arabinonucleoside 5'-phosphate)
C: fanasil (aka sulfadoxine)
D: faman (aka n-fluoroacetylmannosamine)
E: anft
F: ffpeaht (aka 2-(n-n-3-fluoropropyl-n-(4-fluorophenyl)ethylamino)-5-hydroxytetralin)
G: fansidar (aka fanasil... | H |
<Instruct>: Given the context 'FANFT-induced cell proliferation in the bladder was significantly suppressed by aspirin co-administration after 4 weeks but not after 12 weeks.', select the correct biomedical concept corresponding to 'aspirin'. Answer using one of the provided options. | <Options>: A: acetylsalicylsalicylic acid
B: acetyl-p-aminobenzoic acid (aka acedoben)
C: 2-(acetoxymethyl)benzoic acid
D: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
E: aspirin-like agent (aka anti-inflammatory agents, non-steroidal)
F: hs-aspirin (aka 4-(... | G |
<Instruct>: Given the context 'In the forestomach, and also in the liver, aspirin did not affect the FANFT-induced increase in labeling index.', select the correct biomedical concept corresponding to 'aspirin'. Answer using one of the provided options. | <Options>: A: nosh-aspirin (aka 4-(3-thioxo-3h-1,2-dithiol-5-yl)phenyl 2-((4-(nitrooxy)butanoyl)oxy)benzoate)
B: 4-(acetylamino)benzeneacetic acid
C: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
D: acetylsalicylsalicylic acid
E: 2-(acetyloxy)benzoic acid (ak... | E |
<Instruct>: Given the context 'In the forestomach, and also in the liver, aspirin did not affect the FANFT-induced increase in labeling index.', select the correct biomedical concept corresponding to 'fanft'. Answer using one of the provided options. | <Options>: A: fanft
B: fan regimen
C: faman (aka n-fluoroacetylmannosamine)
D: fanaxal (aka alfentanil)
E: ft005 (aka ft 005)
F: anft
G: fanapt (aka iloperidone)
H: flths (aka fluorescein thiosemicarbazide)
I: ara-fump (aka 5-fluorouracil arabinonucleoside 5'-phosphate)
J: fantac
K: None of the above. | A |
<Instruct>: Given the context 'The present results are consistent with the carcinogenicity experiment suggesting that different mechanisms are involved in FANFT carcinogenesis in the bladder and forestomach, and that aspirin's effect on FANFT in the forestomach is not due to an irritant effect associated with increased... | <Options>: A: ara-fump (aka 5-fluorouracil arabinonucleoside 5'-phosphate)
B: fugan fang
C: anft
D: fanft
E: ffpeaht (aka 2-(n-n-3-fluoropropyl-n-(4-fluorophenyl)ethylamino)-5-hydroxytetralin)
F: satfpt (aka succinimidyl 2-(4-azido-2,3,5,6-tetrafluorophenyl)thiazole-4-carboxylate)
G: fanasil (aka sulfadoxine)
H: fantac... | D |
<Instruct>: Given the context 'The present results are consistent with the carcinogenicity experiment suggesting that different mechanisms are involved in FANFT carcinogenesis in the bladder and forestomach, and that aspirin's effect on FANFT in the forestomach is not due to an irritant effect associated with increased... | <Options>: A: hs-aspirin (aka 4-(5-thioxo-5h-1,2-dithiol-3-yl)-phenyl 2-acetoxybenzoate)
B: acetylsalicylic anhydride
C: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
D: aspirin like agent (aka anti-inflammatory agents, non-steroidal)
E: acetylsalicylsalicyli... | F |
<Instruct>: Given the context 'The present results are consistent with the carcinogenicity experiment suggesting that different mechanisms are involved in FANFT carcinogenesis in the bladder and forestomach, and that aspirin's effect on FANFT in the forestomach is not due to an irritant effect associated with increased... | <Options>: A: flths (aka fluorescein thiosemicarbazide)
B: fana cpd (aka 2'-deoxy-2'-fluoro-beta-d-arabinonucleic acid)
C: fansidar (aka fanasil, pyrimethamine drug combination)
D: fanasil (aka sulfadoxine)
E: fanft
F: ft005 (aka ft 005)
G: satfpt (aka succinimidyl 2-(4-azido-2,3,5,6-tetrafluorophenyl)thiazole-4-carbox... | E |
<Instruct>: Given the context 'Also, there appears to be an adaptation by the rats to the chronic ingestion of aspirin.', select the correct biomedical concept corresponding to 'aspirin'. Answer using one of the provided options. | <Options>: A: 4-(acetylamino)benzeneacetic acid
B: 2-(acetoxymethyl)benzoic acid
C: no-aspirin (aka n-acetyl-s-(alpha-methyl-4-(2-methylpropyl)benzeneacetyl)cysteine 4-(nitrooxy)butyl ester)
D: benzoic acid, 2-(acetyloxy)-, anhydride (aka acetylsalicylic anhydride)
E: aspirin-like agent (aka anti-inflammatory agents, n... | H |
<Instruct>: Given the context 'Provocation of postural hypotension by nitroglycerin in diabetic autonomic neuropathy?', select the correct biomedical concept corresponding to 'nitroglycerin'. Answer using one of the provided options. | <Options>: A: nitro-dur (aka nitroglycerin)
B: glycerin-1-nitrate (aka glycerol-1-nitrate)
C: nitropress (aka nitroprusside)
D: 1,2-glyceryl dinitrate (aka dinitroglycerol)
E: 2,2',2''- nitrilotrisethanol, trinitrate (ester) (aka trolnitrate)
F: pentaerythrityl trinitrate (aka pentrinitrol)
G: None of the above. | A |
<Instruct>: Given the context 'The effect of nitroglycerin on heart rate and systolic blood pressure was compared in 5 normal subjects, 12 diabetic subjects without autonomic neuropathy, and 5 diabetic subjects with autonomic neuropathy.', select the correct biomedical concept corresponding to 'nitroglycerin'. Answer u... | <Options>: A: glycerin-1-nitrate (aka glycerol-1-nitrate)
B: 2,2',2''- nitrilotrisethanol, trinitrate (ester) (aka trolnitrate)
C: trinitrin (aka nitroglycerin)
D: pentaerythrityl trinitrate (aka pentrinitrol)
E: glyceryl-1,3-dinitrate (aka dinitroglycerol)
F: nitropress (aka nitroprusside)
G: None of the above. | C |
<Instruct>: Given the context 'The magnitude and time course of the increase in heart rate and the decrease in systolic blood pressure after nitroglycerin were similar in the normal and diabetic subjects without autonomic neuropathy, whereas a lesser increase in heart rate and a greater decrease in systolic blood press... | <Options>: A: nitropress (aka nitroprusside)
B: nitro dur (aka nitroglycerin)
C: 2,2',2''- nitrilotrisethanol, trinitrate (ester) (aka trolnitrate)
D: glycerin-1-nitrate (aka glycerol-1-nitrate)
E: glyceryl-1,3-dinitrate (aka dinitroglycerol)
F: pentaerythrityl trinitrate (aka pentrinitrol)
G: None of the above. | B |
<Instruct>: Given the context 'Characterization of estrogen-induced adenohypophyseal tumors in the Fischer 344 rat.', select the correct biomedical concept corresponding to 'estrogen'. Answer using one of the provided options. | <Options>: A: contraceptive agents, estrogen (aka contraceptives, oral, hormonal)
B: estrogenic compounds (aka estrogens)
C: estrogen, synthetic (aka estradiol congeners)
D: de estrogen (aka 17-(n,n'-diethylethylenediamine)-1,3,5(10)-estratrien-3-ol)
E: None of the above. | B |
<Instruct>: Given the context 'Pituitary tumors were induced in F344 female rats by chronic treatment with diethylstilbestrol (DES, 8-10 mg) implanted subcutaneously in silastic capsules.', select the correct biomedical concept corresponding to 'diethylstilbestrol'. Answer using one of the provided options. | <Options>: A: diethylstilbestrol monomethyl ether, (e)-isomer (aka diethylstilbestrol monomethyl ether)
B: pseudodiethylstilbestrol
C: alpha,alpha-dihydroxydiethylstilbestrol
D: 3'-methoxy-e-diethylstilbestrol
E: diethylstilbestrol dimethyl ether (aka dimestrol)
F: diethylstilbestrol
G: 3,3'-diethylstilbestrol (aka 3,3... | F |
<Instruct>: Given the context 'Pituitary tumors were induced in F344 female rats by chronic treatment with diethylstilbestrol (DES, 8-10 mg) implanted subcutaneously in silastic capsules.', select the correct biomedical concept corresponding to 'des'. Answer using one of the provided options. | <Options>: A: diethylstilbestrol dimethyl ether (aka dimestrol)
B: diethylstilbestrol epoxide, (trans)-isomer (aka diethylstilbestrol epoxide)
C: stilbestrol (aka diethylstilbestrol)
D: alpha,alpha-dihydroxydiethylstilbestrol
E: 3,4,4'-trihydroxy-alpha,alpha'-diethylstilbene
F: 3,3'-dihydroxy-alpha,beta-diethylstilbene... | C |
<Instruct>: Given the context 'Over a range of 1-150 days of DES treatment, pairs of control and DES-treated rats were sacrificed, and their pituitaries dissociated enzymatically into single-cell preparations.', select the correct biomedical concept corresponding to 'des'. Answer using one of the provided options. | <Options>: A: alpha,alpha'-diethyl-4,4'-dimethoxystilbene (aka dimestrol)
B: desogen (contraceptive) (aka oviol)
C: 3,4'-dihydroxy-alpha,beta-diethylstilbene
D: 3,4,4'-trihydroxy-alpha,alpha'-diethylstilbene
E: diethylstilbestrol
F: pseudo-des (aka pseudodiethylstilbestrol)
G: diethylstilbestrol alpha,alpha'-epoxide (a... | E |
<Instruct>: Given the context 'Over a range of 1-150 days of DES treatment, pairs of control and DES-treated rats were sacrificed, and their pituitaries dissociated enzymatically into single-cell preparations.', select the correct biomedical concept corresponding to 'des'. Answer using one of the provided options. | <Options>: A: des dimethyl ether (aka dimestrol)
B: 3,4'-dihydroxy-alpha,beta-diethylstilbene
C: pseudo-des (aka pseudodiethylstilbestrol)
D: diethylstilbestrol epoxide, (cis)-isomer (aka diethylstilbestrol epoxide)
E: desogen (contraceptive) (aka oviol)
F: diethylstilbestrol
G: 3,4,4'-trihydroxy-alpha,alpha'-diethylst... | F |
<Instruct>: Given the context 'The cell populations were examined regarding total cell recovery correlated with gland weight, intracellular prolactin (PRL) content and subsequent release in primary culture, immunocytochemical PRL staining, density and/or size alterations via separation on Ficoll-Hypaque and by unit gra... | <Options>: A: lumiflavin
B: acriflavine hydrochloride (aka acriflavine chloride)
C: acriflavine
D: 9(10h)-acridinone, 1,3-dihydroxy-2,5,6-trimethoxy-10-methyl- (aka atalafoline)
E: methyl-ethyl-monohydro-lumiflavin
F: tetramethylacriflavine
G: acriquinoline b
H: acridinium, 10-methyl- (aka n-methylacridine)
I: armepavi... | C |
<Instruct>: Given the context 'Total cell yields from DES-treated pituitaries increased from 1.3 times control yields at 8 days of treatment to 58.9 times control values by day 150.', select the correct biomedical concept corresponding to 'des'. Answer using one of the provided options. | <Options>: A: alpha,alpha'-diethyl-4,4'-dimethoxystilbene (aka dimestrol)
B: 3,4,4'-trihydroxy-alpha,alpha'-diethylstilbene
C: diethylstilbestrol vicinal diol (aka alpha,alpha-dihydroxydiethylstilbestrol)
D: diethylstilbestrol epoxide
E: 3,4'-dihydroxy-alpha,beta-diethylstilbene
F: desogen (contraceptive) (aka oviol)
G... | H |
<Instruct>: Given the context 'Intracellular PRL content ranged from 1.9 to 9.4 times control levels, and PRL release in vitro was significantly and consistently higher than controls, after at least 8 days of DES exposure.', select the correct biomedical concept corresponding to 'des'. Answer using one of the provided ... | <Options>: A: diethylstilbestrol epoxide, (trans)-isomer (aka diethylstilbestrol epoxide)
B: 3,4'-dihydroxy-alpha,beta-diethylstilbene
C: pseudo-des (aka pseudodiethylstilbestrol)
D: diethylstilbestrol vicinal diol (aka alpha,alpha-dihydroxydiethylstilbestrol)
E: des dimethyl ether (aka dimestrol)
F: 3,4,4'-trihydroxy-... | H |
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