query stringlengths 53 140 | positive listlengths 1 5 | negative listlengths 1 4 | system stringlengths 64 1.31k |
|---|---|---|---|
What is the biomedical concept corresponding to 'hypertensive'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"systolic hypertension",
"primary hypertensions",
"pre hypertension"
] | Given the context 'In unanesthetized, spontaneously hypertensive rats the decrease in blood pressure and heart rate produced by intravenous clonidine, 5 to 20 micrograms/kg, was inhibited or reversed by nalozone, 0.2 to 2 mg/kg.', answer the user's query. |
What is the biomedical concept corresponding to 'hypotensive'? | [
"hypotension",
"vascular hypotension",
"hypotension, vascular",
"low blood pressure",
"blood pressure, low"
] | [
"transfusion reactions, hypotensive",
"hypovolemics",
"postural hypotension",
"transfusion reaction, hypotensive"
] | Given the context 'The hypotensive effect of 100 mg/kg alpha-methyldopa was also partially reversed by naloxone.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertensive'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"systolic hypertension",
"primary hypertensions",
"pre hypertension"
] | Given the context 'In brain membranes from spontaneously hypertensive rats clonidine, 10(-8) to 10(-5) M, did not influence stereoselective binding of [3H]-naloxone (8 nM), and naloxone, 10(-8) to 10(-4) M, did not influence clonidine-suppressible binding of [3H]-dihydroergocryptine (1 nM).', answer the user's query. |
What is the biomedical concept corresponding to 'hypertensive'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"systolic hypertension",
"primary hypertensions",
"pre hypertension"
] | Given the context 'These findings indicate that in spontaneously hypertensive rats the effects of central alpha-adrenoceptor stimulation involve activation of opiate receptors.', answer the user's query. |
What is the biomedical concept corresponding to 'cardiac asystole'? | [
"asystole",
"asystoles",
"arrest, cardiac",
"arrest, heart",
"cardiac arrest"
] | [
"parasystole",
"arrest, sudden cardiac",
"cardiac arrest, sudden",
"sudden cardiac arrest"
] | Given the context 'Lidocaine-induced cardiac asystole.', answer the user's query. |
What is the biomedical concept corresponding to 'depression'? | [
"depressive disorders",
"depressive disorder",
"disorders, depressive",
"disorder, depressive",
"depressive syndromes"
] | [
"clinical depression",
"major depressive disorders",
"major depressive disorder",
"depressive disorders, major"
] | Given the context 'Intravenous administration of a single 50-mg bolus of lidocaine in a 67-year-old man resulted in profound depression of the activity of the sinoatrial and atrioventricular nodal pacemakers.', answer the user's query. |
What is the biomedical concept corresponding to 'bradyarrhythmias'? | [
"bradyarrhythmias",
"bradyarrhythmia",
"bradycardias",
"bradycardia"
] | [
"block, heart",
"blocks, heart",
"heart block",
"atrioventricular blocks"
] | Given the context 'The patient had no apparent associated conditions which might have predisposed him to the development of bradyarrhythmias; and, thus, this probably represented a true idiosyncrasy to lidocaine.', answer the user's query. |
What is the biomedical concept corresponding to 'fasciculations'? | [
"fasciculations",
"fasciculation",
"fasciculations, muscular",
"muscular fasciculations",
"fasciculation, muscular"
] | [
"spasms, muscle",
"muscle spasms",
"syndrome, cramp-fasciculation",
"syndromes, cramp-fasciculation"
] | Given the context 'Suxamethonium infusion rate and observed fasciculations.', answer the user's query. |
What is the biomedical concept corresponding to 'tetanic'? | [
"tetany",
"tetanies"
] | [
"tetanus",
"spasms",
"muscular spasms",
"aches"
] | Given the context 'The infusion was discontinued either when there was no muscular response to tetanic stimulation of the ulnar nerve or when Sch 120 mg was exceeded.', answer the user's query. |
What is the biomedical concept corresponding to 'fasciculations'? | [
"fasciculations",
"fasciculation",
"fasciculations, muscular",
"muscular fasciculations",
"fasciculation, muscular"
] | [
"spasms, muscle",
"muscle spasms",
"syndrome, cramp-fasciculation",
"syndromes, cramp-fasciculation"
] | Given the context 'Fasciculations in six areas of the body were scored from 0 to 3 and summated as a total fasciculation score.', answer the user's query. |
What is the biomedical concept corresponding to 'fasciculation'? | [
"fasciculation",
"fasciculations",
"fasciculations, muscular",
"fasciculation, muscular",
"muscular fasciculations"
] | [
"spasms, muscle",
"muscle spasms",
"muscle tremors",
"spasm, muscle"
] | Given the context 'Fasciculations in six areas of the body were scored from 0 to 3 and summated as a total fasciculation score.', answer the user's query. |
What is the biomedical concept corresponding to 'fasciculation'? | [
"fasciculation",
"fasciculations",
"fasciculations, muscular",
"fasciculation, muscular",
"muscular fasciculations"
] | [
"spasms, muscle",
"muscle spasms",
"muscle tremors",
"spasm, muscle"
] | Given the context 'The times to first fasciculation, twitch suppression and tetanus suppression were inversely related to the infusion rates.', answer the user's query. |
What is the biomedical concept corresponding to 'twitch'? | [
"tetany",
"tetanies"
] | [
"spasms",
"aches",
"spasms, muscle",
"tetanus"
] | Given the context 'The times to first fasciculation, twitch suppression and tetanus suppression were inversely related to the infusion rates.', answer the user's query. |
What is the biomedical concept corresponding to 'tetanus'? | [
"tetanies",
"tetany",
"neonatal tetanies",
"tetanies, neonatal"
] | [
"tetanus",
"infections, clostridium tetani",
"infection, clostridium tetani",
"clostridium tetani infection"
] | Given the context 'The times to first fasciculation, twitch suppression and tetanus suppression were inversely related to the infusion rates.', answer the user's query. |
What is the biomedical concept corresponding to 'fasciculations'? | [
"fasciculations",
"fasciculation",
"fasciculations, muscular",
"muscular fasciculations",
"fasciculation, muscular"
] | [
"spasms, muscle",
"muscle spasms",
"syndrome, cramp-fasciculation",
"syndromes, cramp-fasciculation"
] | Given the context 'Fasciculations in the six areas and the total fasciculation score were related directly to the rate of infusion.', answer the user's query. |
What is the biomedical concept corresponding to 'fasciculation'? | [
"fasciculation",
"fasciculations",
"fasciculations, muscular",
"fasciculation, muscular",
"muscular fasciculations"
] | [
"spasms, muscle",
"muscle spasms",
"muscle tremors",
"spasm, muscle"
] | Given the context 'Fasciculations in the six areas and the total fasciculation score were related directly to the rate of infusion.', answer the user's query. |
What is the biomedical concept corresponding to 'fasciculation'? | [
"fasciculation",
"fasciculations",
"fasciculations, muscular",
"fasciculation, muscular",
"muscular fasciculations"
] | [
"spasms, muscle",
"muscle spasms",
"muscle tremors",
"spasm, muscle"
] | Given the context 'Total fasciculation scores in the 30-mg bolus group and the 5-mg s-1 and 20-mg s-1 infusion groups were not significantly different.', answer the user's query. |
What is the biomedical concept corresponding to 'overdosage'? | [
"overdose, drug",
"drug overdose",
"overdoses, drug",
"drug overdoses"
] | [
"overuse, medication",
"overuses, medication",
"medication overuse",
"overuse, prescription drug"
] | Given the context 'Galanthamine hydrobromide, an anticholinesterase drug capable of penetrating the blood-brain barrier, was used in a patient demonstrating central effects of scopolamine (hyoscine) overdosage.', answer the user's query. |
What is the biomedical concept corresponding to 'chronic renal failure'? | [
"chronic renal failure",
"renal failure, chronic",
"chronic kidney failure",
"kidney failure, chronic",
"esrd (kidney failure, chronic)"
] | [
"disease, chronic renal",
"chronic renal disease",
"renal disease, chronic",
"diseases, chronic renal"
] | Given the context 'Effects of uninephrectomy and high protein feeding on lithium-induced chronic renal failure in rats.', answer the user's query. |
What is the biomedical concept corresponding to 'nephropathy'? | [
"diseases, kidney",
"kidney diseases",
"disease, kidney",
"kidney disease"
] | [
"nephrosis",
"nephritis",
"glomerulonephritis",
"diabetic nephropathy"
] | Given the context 'Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure.', answer the user's query. |
What is the biomedical concept corresponding to 'renal failure'? | [
"renal failure",
"failure, renal",
"renal failures",
"kidney failure",
"failures, renal"
] | [
"acute renal failure",
"renal failure, acute",
"acute renal failures",
"renal failures, acute"
] | Given the context 'Rats with lithium-induced nephropathy were subjected to high protein (HP) feeding, uninephrectomy (NX) or a combination of these, in an attempt to induce glomerular hyperfiltration and further progression of renal failure.', answer the user's query. |
What is the biomedical concept corresponding to 'proteinuria'? | [
"proteinuria",
"proteinurias"
] | [
"albuminuria",
"albuminurias",
"nephrotic syndromes",
"nephrotic syndrome"
] | Given the context 'Lithium also caused proteinuria and systolic hypertension in absence of glomerulosclerosis.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertension'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"primary hypertensions",
"hypertension, primary",
"hypertensions, primary"
] | Given the context 'Lithium also caused proteinuria and systolic hypertension in absence of glomerulosclerosis.', answer the user's query. |
What is the biomedical concept corresponding to 'glomerulosclerosis'? | [
"glomerulonephritides",
"glomerulonephritis"
] | [
"diseases, kidney",
"disease, kidney",
"focal glomerulosclerosis",
"kidney diseases"
] | Given the context 'Lithium also caused proteinuria and systolic hypertension in absence of glomerulosclerosis.', answer the user's query. |
What is the biomedical concept corresponding to 'renal failure'? | [
"renal failure",
"failure, renal",
"renal failures",
"kidney failure",
"failures, renal"
] | [
"acute renal failure",
"renal failure, acute",
"acute renal failures",
"renal failures, acute"
] | Given the context 'HP failed to accentuante progression of renal failure and in fact tended to increase GFR and decrease plasma creatinine levels in lithium pretreated rats.', answer the user's query. |
What is the biomedical concept corresponding to 'nephropathy'? | [
"diseases, kidney",
"kidney diseases",
"disease, kidney",
"kidney disease"
] | [
"nephrosis",
"nephritis",
"glomerulonephritis",
"diabetic nephropathy"
] | Given the context 'The results indicate that Li-induced nephropathy, even when the GFR is only modestly reduced, is associated with proteinuria and arterial systolic hypertension.', answer the user's query. |
What is the biomedical concept corresponding to 'proteinuria'? | [
"proteinuria",
"proteinurias"
] | [
"albuminuria",
"albuminurias",
"nephrotic syndromes",
"nephrotic syndrome"
] | Given the context 'The results indicate that Li-induced nephropathy, even when the GFR is only modestly reduced, is associated with proteinuria and arterial systolic hypertension.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertension'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"primary hypertensions",
"hypertension, primary",
"hypertensions, primary"
] | Given the context 'The results indicate that Li-induced nephropathy, even when the GFR is only modestly reduced, is associated with proteinuria and arterial systolic hypertension.', answer the user's query. |
What is the biomedical concept corresponding to 'chronic renal failure'? | [
"chronic renal failure",
"renal failure, chronic",
"chronic kidney failure",
"kidney failure, chronic",
"esrd (kidney failure, chronic)"
] | [
"disease, chronic renal",
"chronic renal disease",
"renal disease, chronic",
"diseases, chronic renal"
] | Given the context 'In this model of chronic renal failure the decline in GFR is not accompanied by a corresponding fall in effective renal plasma flow, which may be the functional expression of the formation of nonfiltrating atubular glomeruli.', answer the user's query. |
What is the biomedical concept corresponding to 'crohn's disease'? | [
"crohn's disease",
"crohns disease",
"crohn disease",
"crohn's enteritis",
"regional enteritis"
] | [
"bowel diseases, inflammatory",
"inflammatory bowel disease (crohn disease) 1",
"inflammatory bowel disease",
"inflammatory bowel diseases"
] | Given the context 'Treatment of Crohn's disease with fusidic acid: an antibiotic with immunosuppressive properties similar to cyclosporin.', answer the user's query. |
What is the biomedical concept corresponding to 'crohn's disease'? | [
"crohn's disease",
"crohns disease",
"crohn disease",
"crohn's enteritis",
"regional enteritis"
] | [
"bowel diseases, inflammatory",
"inflammatory bowel disease (crohn disease) 1",
"inflammatory bowel disease",
"inflammatory bowel diseases"
] | Given the context 'Because of the need for the development of new treatments for Crohn's disease, a pilot study was undertaken to estimate the pharmacodynamics and tolerability of fusidic acid treatment in chronic active, therapy-resistant patients.', answer the user's query. |
What is the biomedical concept corresponding to 'crohn's disease'? | [
"crohn's disease",
"crohns disease",
"crohn disease",
"crohn's enteritis",
"regional enteritis"
] | [
"bowel diseases, inflammatory",
"inflammatory bowel disease (crohn disease) 1",
"inflammatory bowel disease",
"inflammatory bowel diseases"
] | Given the context 'Eight Crohn's disease patients were included.', answer the user's query. |
What is the biomedical concept corresponding to 'nausea'? | [
"nausea"
] | [
"postoperative nausea",
"nausea, postoperative",
"aches",
"dizziness"
] | Given the context 'There were no serious clinical side effects, but dose reduction was required in two patients because of nausea.', answer the user's query. |
What is the biomedical concept corresponding to 'crohn's disease'? | [
"crohn's disease",
"crohns disease",
"crohn disease",
"crohn's enteritis",
"regional enteritis"
] | [
"bowel diseases, inflammatory",
"inflammatory bowel disease (crohn disease) 1",
"inflammatory bowel disease",
"inflammatory bowel diseases"
] | Given the context 'The results of this pilot study suggest that fusidic acid may be of benefit in selected chronic active Crohn's disease patients in whom conventional treatment is ineffective.', answer the user's query. |
What is the biomedical concept corresponding to 'inflammatory bowel disease'? | [
"bowel diseases, inflammatory",
"inflammatory bowel diseases",
"inflammatory bowel disease",
"ibd1 (inflammatory bowel diseases)"
] | [
"diseases, intestinal",
"disease, intestinal",
"intestinal diseases",
"enteritis"
] | Given the context 'Because there seems to exist a scientific rationale for the use of fusidic acid at the cytokine level in inflammatory bowel disease, we suggest that the role of this treatment should be further investigated.', answer the user's query. |
What is the biomedical concept corresponding to 'myocardial injury'? | [
"disease, myocardial",
"diseases, myocardial",
"myocardial diseases",
"myocardial disease",
"cardiomyopathies"
] | [
"injury, heart",
"myocardial failure",
"heart injury",
"cardiac diseases"
] | Given the context 'Electrocardiographic evidence of myocardial injury in psychiatrically hospitalized cocaine abusers.', answer the user's query. |
What is the biomedical concept corresponding to 'schizophrenic'? | [
"schizophrenic disorder",
"schizophrenic disorders",
"disorder, schizophrenic",
"disorders, schizophrenic",
"schizophrenias"
] | [
"drug psychoses",
"psychoses, drug",
"psychosis",
"psychotic disorder"
] | Given the context 'The electrocardiograms (ECG) of 99 cocaine-abusing patients were compared with the ECGs of 50 schizophrenic controls.', answer the user's query. |
What is the biomedical concept corresponding to 'myocardial injury'? | [
"disease, myocardial",
"diseases, myocardial",
"myocardial diseases",
"myocardial disease",
"cardiomyopathies"
] | [
"injury, heart",
"myocardial failure",
"heart injury",
"cardiac diseases"
] | Given the context 'Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block.', answer the user's query. |
What is the biomedical concept corresponding to 'myocardial infarction'? | [
"infarction, myocardial",
"myocardial infarction",
"myocardial infarctions",
"infarctions, myocardial",
"myocardial infarct"
] | [
"infarction",
"disease, myocardial",
"infarctions",
"myocardial disease"
] | Given the context 'Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block.', answer the user's query. |
What is the biomedical concept corresponding to 'ischemia'? | [
"ischemia",
"ischemias"
] | [
"heart diseases, ischemic",
"diseases, ischemic heart",
"heart disease, ischemic",
"disease, ischemic heart"
] | Given the context 'Eleven of the cocaine abusers and none of the controls had ECG evidence of significant myocardial injury defined as myocardial infarction, ischemia, and bundle branch block.', answer the user's query. |
What is the biomedical concept corresponding to 'tardive dystonia'? | [
"dystonia",
"dystonia, muscle",
"dystonia, limb",
"muscle dystonia",
"limb dystonia"
] | [
"tardive dystonia",
"tardive dystonias",
"dystonia disorder",
"dystonia disorders"
] | Given the context 'Sulpiride-induced tardive dystonia.', answer the user's query. |
What is the biomedical concept corresponding to 'tardive dyskinesia'? | [
"dyskinesia, drug-induced",
"drug-induced dyskinesia",
"dyskinesias, drug-induced",
"drug-induced dyskinesias",
"dyskinesia, medication-induced"
] | [
"tardive dyskinesias",
"tardive dyskinesia",
"dyskinesias, tardive",
"dyskinesia, tardive"
] | Given the context 'Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally.', answer the user's query. |
What is the biomedical concept corresponding to 'parkinsonism'? | [
"parkinsonism, symptomatic",
"symptomatic parkinsonism",
"parkinson disease, symptomatic",
"symptomatic parkinson disease"
] | [
"parkinsonism",
"parkinson's disease",
"parkinson disease",
"parkinsonian diseases"
] | Given the context 'Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally.', answer the user's query. |
What is the biomedical concept corresponding to 'dystonia'? | [
"dystonia",
"dystonia, muscle",
"muscle dystonia",
"dystonia, limb",
"limb dystonia"
] | [
"dystonia disorder",
"dystonia disorders",
"drug-induced dyskinesia",
"drug-induced dyskinesias"
] | Given the context 'We studied a 37-year-old man who developed persistent segmental dystonia within 2 months after starting sulpiride therapy.', answer the user's query. |
What is the biomedical concept corresponding to 'tardive dystonia'? | [
"dystonia",
"dystonia, muscle",
"dystonia, limb",
"muscle dystonia",
"limb dystonia"
] | [
"tardive dystonia",
"tardive dystonias",
"dystonia disorder",
"dystonia disorders"
] | Given the context 'We could not find any previous reports of sulpiride-induced tardive dystonia.', answer the user's query. |
What is the biomedical concept corresponding to 'visual toxicity'? | [
"disorders, visual",
"visual disorders",
"disorder, visual",
"visual disorder",
"vision disorders"
] | [
"reduced vision",
"diminished vision",
"vision, reduced",
"eye disorders"
] | Given the context 'Visual toxicity was of retinal origin and was characterized by a tritan-type dyschromatopsy, sometimes associated with a loss of visual acuity and pigmentary retinal deposits.', answer the user's query. |
What is the biomedical concept corresponding to 'a loss of visual acuity'? | [
"disabilities, vision",
"disability, vision",
"vision disorder",
"visual disorder",
"vision disorders"
] | [
"reduced vision",
"diminished vision",
"vision, reduced",
"vision, diminished"
] | Given the context 'Visual toxicity was of retinal origin and was characterized by a tritan-type dyschromatopsy, sometimes associated with a loss of visual acuity and pigmentary retinal deposits.', answer the user's query. |
What is the biomedical concept corresponding to 'auditory toxicity'? | [
"hearing disorders",
"hearing disorder"
] | [
"auditory toxicity",
"hearing impairment",
"hearing loss",
"loss, hearing"
] | Given the context 'Auditory toxicity was characterized by a mid- to high-frequency neurosensorial hearing loss and the lesion was of the cochlear type.', answer the user's query. |
What is the biomedical concept corresponding to 'neurosensorial hearing loss'? | [
"deafnesses, neurosensory",
"neurosensory deafnesses",
"neurosensory deafness",
"deafness, neurosensory",
"deafness neurosensory"
] | [
"loss, hearing",
"hearing loss",
"hearing disorder",
"hearing disorders"
] | Given the context 'Auditory toxicity was characterized by a mid- to high-frequency neurosensorial hearing loss and the lesion was of the cochlear type.', answer the user's query. |
What is the biomedical concept corresponding to 'hearing loss'? | [
"loss, hearing",
"hearing loss",
"hearing impairment"
] | [
"hearing disorder",
"hearing disorders",
"hearing loss, functional",
"functional hearing loss"
] | Given the context 'Desferrioxamine withdrawal resulted in a complete recovery of visual function in 1 patient and partial recovery in 3, and a complete reversal of hearing loss in 3 patients and partial recovery in 3.', answer the user's query. |
What is the biomedical concept corresponding to 'toxicity'? | [
"toxicity, drug",
"drug toxicity",
"toxicities, drug",
"drug toxicities",
"side effects of drugs"
] | [
"poisonings",
"poisoning",
"diseases",
"diseases (disease)"
] | Given the context 'This toxicity appeared in patients receiving the higher doses of desferrioxamine or coincided with the normalization of ferritin or aluminium serum levels.', answer the user's query. |
What is the biomedical concept corresponding to 'myasthenia gravis'? | [
"myasthenia gravis",
"myasthenia gravis, generalized",
"generalized myasthenia gravis",
"musk myasthenia gravis"
] | [
"myasthenia gravis, experimental",
"experimental myasthenia gravis",
"neurasthenia",
"myasthenias, experimental"
] | Given the context 'Myasthenia gravis presenting as weakness after magnesium administration.', answer the user's query. |
What is the biomedical concept corresponding to 'neuromuscular disease'? | [
"neuromuscular diseases",
"neuromuscular disease"
] | [
"signs and symptoms, neuromuscular",
"muscular diseases",
"muscular disease",
"neuromuscular signs and symptoms"
] | Given the context 'We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia.', answer the user's query. |
What is the biomedical concept corresponding to 'quadriplegic'? | [
"quadriplegias",
"quadriplegia",
"quadripareses",
"quadriparesis",
"paralysis, spinal, quadriplegic"
] | [
"paraplegias",
"paraplegia",
"infantile cerebral palsy, quadriplegic",
"hemiplegia"
] | Given the context 'We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia.', answer the user's query. |
What is the biomedical concept corresponding to 'preeclampsia'? | [
"preeclampsia",
"pee (pre-eclampsia)",
"pre-eclampsia",
"pre eclampsia",
"preeclampsia eclampsia 1"
] | [
"eclampsia",
"eclampsias",
"preeclamptic toxemia",
"prom (pregnancy)"
] | Given the context 'We studied a patient with no prior history of neuromuscular disease who became virtually quadriplegic after parenteral magnesium administration for preeclampsia.', answer the user's query. |
What is the biomedical concept corresponding to 'postsynaptic neuromuscular blockade'? | [
"neuromuscular diseases",
"neuromuscular disease"
] | [
"signs and symptoms, neuromuscular",
"neuromuscular signs and symptoms",
"neuromuscular junction disorders",
"neuromuscular manifestations"
] | Given the context 'While she was weak, 2-Hz repetitive stimulation revealed a decrement without significant facilitation at rapid rates or after exercise, suggesting postsynaptic neuromuscular blockade.', answer the user's query. |
What is the biomedical concept corresponding to 'paralysis'? | [
"paralysis",
"paralyses",
"palsies",
"palsy"
] | [
"paresis",
"pareses",
"general paralysis",
"paralysis, general"
] | Given the context 'Although paralysis after magnesium administration has been described in patients with known myasthenia gravis, it has not previously been reported to be the initial or only manifestation of the disease.', answer the user's query. |
What is the biomedical concept corresponding to 'myasthenia gravis'? | [
"myasthenia gravis",
"myasthenia gravis, generalized",
"generalized myasthenia gravis",
"musk myasthenia gravis"
] | [
"myasthenia gravis, experimental",
"experimental myasthenia gravis",
"neurasthenia",
"myasthenias, experimental"
] | Given the context 'Although paralysis after magnesium administration has been described in patients with known myasthenia gravis, it has not previously been reported to be the initial or only manifestation of the disease.', answer the user's query. |
What is the biomedical concept corresponding to 'disorder of neuromuscular transmission'? | [
"neuromuscular transmission disorder",
"neuromuscular transmission disorders",
"neuromuscular junction disorders",
"neuromuscular junction disorder",
"neuromuscular junction diseases"
] | [
"neuromuscular diseases",
"neuromuscular disease",
"signs and symptoms, neuromuscular",
"neuromuscular signs and symptoms"
] | Given the context 'Patients who are unusually sensitive to the neuromuscular effects of magnesium should be suspected of having an underlying disorder of neuromuscular transmission.', answer the user's query. |
What is the biomedical concept corresponding to 'bladder damage'? | [
"bladder diseases",
"bladder disease",
"urinary bladder diseases",
"urinary bladder disease"
] | [
"urinary tract diseases",
"urinary tract disease",
"diseases, urinary tract",
"disease, urinary tract"
] | Given the context 'The data demonstrate that CAA after i.v. administration does not contribute to bladder damage.', answer the user's query. |
What is the biomedical concept corresponding to 'pain'? | [
"pain",
"ache (pain)",
"aches"
] | [
"pain disorder",
"pain, acute",
"nociceptive pain",
"acute pain"
] | Given the context 'Source of pain and primitive dysfunction in migraine: an identical site?', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'Source of pain and primitive dysfunction in migraine: an identical site?', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'Twenty common migraine patients received a one sided frontotemporal application of nitroglycerin (10 patients) or placebo ointment (10 patients) in a double blind study.', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'Early onset migraine attacks were induced by nitroglycerin in seven out of 10 patients versus no patient in the placebo group.', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'Subsequently 20 migraine patients, who developed an early onset attack with frontotemporal nitroglycerin, received the drug in a second induction test at other body areas.', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'No early onset migraine was observed.', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'Thus the migraine-inducing effect of nitroglycerin seems to depend on direct stimulation of the habitual site of pain, suggesting that the frontotemporal region is of crucial importance in the development of a migraine crisis.', answer the user's query. |
What is the biomedical concept corresponding to 'pain'? | [
"pain",
"ache (pain)",
"aches"
] | [
"pain disorder",
"pain, acute",
"nociceptive pain",
"acute pain"
] | Given the context 'Thus the migraine-inducing effect of nitroglycerin seems to depend on direct stimulation of the habitual site of pain, suggesting that the frontotemporal region is of crucial importance in the development of a migraine crisis.', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'Thus the migraine-inducing effect of nitroglycerin seems to depend on direct stimulation of the habitual site of pain, suggesting that the frontotemporal region is of crucial importance in the development of a migraine crisis.', answer the user's query. |
What is the biomedical concept corresponding to 'migraine'? | [
"migraines",
"migraine (migraine disorders)",
"disorders, migraine",
"disorder, migraine",
"migraine disorders"
] | [
"common migraines",
"common migraine",
"migraines, common",
"headache"
] | Given the context 'This is not consistent with a CNS origin of migraine attack.', answer the user's query. |
What is the biomedical concept corresponding to 'hepatitis'? | [
"hepatitis, drug-induced",
"drug-induced hepatitis",
"hepatitis, drug induced",
"toxic hepatitis",
"hepatitis, toxic"
] | [
"hepatitis",
"diseases, liver",
"hepatitis, viral, human",
"disease, liver"
] | Given the context 'Clotiazepam-induced acute hepatitis.', answer the user's query. |
What is the biomedical concept corresponding to 'hepatitis'? | [
"hepatitis, drug-induced",
"drug-induced hepatitis",
"hepatitis, drug induced",
"toxic hepatitis",
"hepatitis, toxic"
] | [
"hepatitis",
"diseases, liver",
"hepatitis, viral, human",
"disease, liver"
] | Given the context 'We report the case of a patient who developed acute hepatitis with extensive hepatocellular necrosis, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative.', answer the user's query. |
What is the biomedical concept corresponding to 'extensive hepatocellular necrosis'? | [
"massive hepatic necrosis",
"hepatic necrosis, massive",
"drug-induced hepatic necrosis",
"necrosis, drug-induced hepatic",
"hepatic necrosis, drug-induced"
] | [
"toxic hepatitis",
"end stage liver disease",
"hepatitis, toxic",
"leigh's disease"
] | Given the context 'We report the case of a patient who developed acute hepatitis with extensive hepatocellular necrosis, 7 months after the onset of administration of clotiazepam, a thienodiazepine derivative.', answer the user's query. |
What is the biomedical concept corresponding to 'hepatitis'? | [
"hepatitis, drug-induced",
"drug-induced hepatitis",
"hepatitis, drug induced",
"toxic hepatitis",
"hepatitis, toxic"
] | [
"hepatitis",
"diseases, liver",
"hepatitis, viral, human",
"disease, liver"
] | Given the context 'The administration of several benzodiazepines, chemically related to clotiazepam, did not interfere with recovery and did not induce any relapse of hepatitis.', answer the user's query. |
What is the biomedical concept corresponding to 'hepatitis'? | [
"hepatitis, drug-induced",
"drug-induced hepatitis",
"hepatitis, drug induced",
"toxic hepatitis",
"hepatitis, toxic"
] | [
"hepatitis",
"diseases, liver",
"hepatitis, viral, human",
"disease, liver"
] | Given the context 'This observation shows that clotiazepam can induce acute hepatitis and suggests that there is no cross hepatotoxicity between clotiazepam and several benzodiazepines.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertension'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"primary hypertensions",
"hypertension, primary",
"hypertensions, primary"
] | Given the context 'Arterial hypertension as a complication of prolonged ketoconazole treatment.', answer the user's query. |
What is the biomedical concept corresponding to 'cushing's syndrome'? | [
"syndrome, cushing's",
"syndrome, cushing",
"cushing's syndrome",
"cushing syndrome",
"hypercortisolism"
] | [
"disease, cushing",
"cushing's disease",
"cushing disease",
"cushing syndrome, pituitary"
] | Given the context 'Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained hypertension.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertension'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"primary hypertensions",
"hypertension, primary",
"hypertensions, primary"
] | Given the context 'Two of 14 patients with Cushing's syndrome treated on a long-term basis with ketoconazole developed sustained hypertension.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertension'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"primary hypertensions",
"hypertension, primary",
"hypertensions, primary"
] | Given the context 'In both cases normal plasma and urinary free cortisol levels had been achieved following ketoconazole therapy, yet continuous blood pressure monitoring demonstrated hypertension 31 (patient 1) and 52 weeks (patient 2) after treatment.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertension'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"primary hypertensions",
"hypertension, primary",
"hypertensions, primary"
] | Given the context 'Our findings show that long-term treatment with high doses of ketoconazole may induce enzyme blockade leading to mineralocorticoid-related hypertension.', answer the user's query. |
What is the biomedical concept corresponding to 'intravascular coagulation'? | [
"coagulations, disseminated intravascular",
"coagulation, disseminated intravascular",
"disseminated coagulations, intravascular",
"intravascular disseminated coagulations",
"intravascular disseminated coagulation"
] | [
"coagulation disorders, blood",
"coagulation disorder, blood",
"blood coagulation disorders",
"blood coagulation disorder"
] | Given the context 'Effects of an inhibitor of angiotensin converting enzyme (Captopril) on pulmonary and renal insufficiency due to intravascular coagulation in the rat.', answer the user's query. |
What is the biomedical concept corresponding to 'intravascular coagulation'? | [
"coagulations, disseminated intravascular",
"coagulation, disseminated intravascular",
"disseminated coagulations, intravascular",
"intravascular disseminated coagulations",
"intravascular disseminated coagulation"
] | [
"coagulation disorders, blood",
"coagulation disorder, blood",
"blood coagulation disorders",
"blood coagulation disorder"
] | Given the context 'Induction of intravascular coagulation and inhibition of fibrinolysis by injection of thrombin and tranexamic acid (AMCA) in the rat gives rise to pulmonary and renal insufficiency resembling that occurring after trauma or sepsis in man.', answer the user's query. |
What is the biomedical concept corresponding to 'trauma'? | [
"traumas",
"trauma",
"injuries",
"trauma, physical",
"physical trauma"
] | [
"trauma, psychological",
"injuries, accident",
"surgical injuries",
"psychological trauma"
] | Given the context 'Induction of intravascular coagulation and inhibition of fibrinolysis by injection of thrombin and tranexamic acid (AMCA) in the rat gives rise to pulmonary and renal insufficiency resembling that occurring after trauma or sepsis in man.', answer the user's query. |
What is the biomedical concept corresponding to 'sepsis'? | [
"sepsis",
"septicemias",
"septicemia",
"severe sepsis",
"sepsis, severe"
] | [
"syndrome, sepsis",
"sepsis syndrome",
"syndromes, sepsis",
"sepsis syndromes"
] | Given the context 'Induction of intravascular coagulation and inhibition of fibrinolysis by injection of thrombin and tranexamic acid (AMCA) in the rat gives rise to pulmonary and renal insufficiency resembling that occurring after trauma or sepsis in man.', answer the user's query. |
What is the biomedical concept corresponding to 'renal damage'? | [
"diseases, kidney",
"kidney diseases",
"disease, kidney",
"kidney disease"
] | [
"acute renal injury",
"renal injury, acute",
"acute renal injuries",
"renal injuries, acute"
] | Given the context 'Renal damage as reflected by an increase in serum urea and in kidney weight was prevented by Captopril.', answer the user's query. |
What is the biomedical concept corresponding to 'kidney damage'? | [
"diseases, kidney",
"disease, kidney",
"kidney diseases",
"kidney disease"
] | [
"kidney injury, acute",
"kidney injuries, acute",
"acute kidney injuries",
"acute kidney injury"
] | Given the context 'Captopril may, by the same mechanism, reduce the increase in glomerular filtration that is known to occur after an injection of thrombin, thereby diminishing the aggregation of fibrin monomers in the glomeruli, with the result that less fibrin will be deposited and thus less kidney damage will be produced.', answer the user's query. |
What is the biomedical concept corresponding to 'hypotension'? | [
"hypotension",
"vascular hypotension",
"hypotension, vascular",
"low blood pressure",
"blood pressure, low"
] | [
"postural hypotension",
"hypotension, postural",
"vascular depression",
"hypotension, orthostatic"
] | Given the context 'A randomized comparison of labetalol and nitroprusside for induced hypotension.', answer the user's query. |
What is the biomedical concept corresponding to 'hypotension'? | [
"hypotension",
"vascular hypotension",
"hypotension, vascular",
"low blood pressure",
"blood pressure, low"
] | [
"postural hypotension",
"hypotension, postural",
"vascular depression",
"hypotension, orthostatic"
] | Given the context 'In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures.', answer the user's query. |
What is the biomedical concept corresponding to 'hypotension'? | [
"hypotension",
"vascular hypotension",
"hypotension, vascular",
"low blood pressure",
"blood pressure, low"
] | [
"postural hypotension",
"hypotension, postural",
"vascular depression",
"hypotension, orthostatic"
] | Given the context 'In a randomized study, labetalol-induced hypotension and nitroprusside-induced hypotension were compared in 20 patients (10 in each group) scheduled for major orthopedic procedures.', answer the user's query. |
What is the biomedical concept corresponding to 'reductions in mean arterial blood pressure'? | [
"low blood pressure",
"blood pressure, low",
"hypotension",
"vascular hypotension",
"hypotension, vascular"
] | [
"vascular depression",
"postural hypotension",
"depression, vascular",
"hypotension, postural"
] | Given the context 'Each patient was subjected to an identical anesthetic protocol and similar drug-induced reductions in mean arterial blood pressure (BP) (50 to 55 mmHg).', answer the user's query. |
What is the biomedical concept corresponding to 'increase in heart rate and cardiac output'? | [
"cardiac output, high",
"cardiac outputs, high",
"high cardiac outputs",
"high cardiac output"
] | [
"hyperemias",
"hypertrophies, cardiac",
"heart hypertrophy",
"hypertrophies, heart"
] | Given the context 'Nitroprusside infusion was associated with a significant (p less than 0.05) increase in heart rate and cardiac output; rebound hypertension was observed in three patients after discontinuation of nitroprusside.', answer the user's query. |
What is the biomedical concept corresponding to 'hypertension'? | [
"hypertension",
"high blood pressure",
"high blood pressures",
"blood pressure, high",
"blood pressures, high"
] | [
"primary hypertension",
"primary hypertensions",
"hypertension, primary",
"hypertensions, primary"
] | Given the context 'Nitroprusside infusion was associated with a significant (p less than 0.05) increase in heart rate and cardiac output; rebound hypertension was observed in three patients after discontinuation of nitroprusside.', answer the user's query. |
What is the biomedical concept corresponding to 'toxicity'? | [
"toxicity, drug",
"drug toxicity",
"toxicities, drug",
"drug toxicities",
"side effects of drugs"
] | [
"poisonings",
"poisoning",
"diseases",
"diseases (disease)"
] | Given the context 'Chronic carbamazepine treatment in the rat: efficacy, toxicity, and effect on plasma and tissue folate concentrations.', answer the user's query. |
What is the biomedical concept corresponding to 'seizures'? | [
"seizures",
"seizure",
"convulsions",
"convulsion",
"convulsive seizures"
] | [
"seizure disorders",
"seizure disorder",
"epilepsies",
"epilepsy"
] | Given the context 'In the course of developing this model, a common vehicle, propylene glycol, by itself in high doses, was found to exhibit protective properties against induced seizures and inhibited weight gain.', answer the user's query. |
What is the biomedical concept corresponding to 'weight gain'? | [
"gain, weight",
"weight gain",
"weight gains",
"gains, weight"
] | [
"body weight change",
"body weight changes",
"weight change, body",
"changes, body weight"
] | Given the context 'In the course of developing this model, a common vehicle, propylene glycol, by itself in high doses, was found to exhibit protective properties against induced seizures and inhibited weight gain.', answer the user's query. |
What is the biomedical concept corresponding to 'seizures'? | [
"seizures",
"seizure",
"convulsions",
"convulsion",
"convulsive seizures"
] | [
"seizure disorders",
"seizure disorder",
"epilepsies",
"epilepsy"
] | Given the context 'Seizures induced by hexafluorodiethyl ether (HFDE) were also found to be a more sensitive measure of protection by CBZ than seizures induced by maximal electroshock (MES).', answer the user's query. |
What is the biomedical concept corresponding to 'seizures'? | [
"seizures",
"seizure",
"convulsions",
"convulsion",
"convulsive seizures"
] | [
"seizure disorders",
"seizure disorder",
"epilepsies",
"epilepsy"
] | Given the context 'Seizures induced by hexafluorodiethyl ether (HFDE) were also found to be a more sensitive measure of protection by CBZ than seizures induced by maximal electroshock (MES).', answer the user's query. |
What is the biomedical concept corresponding to 'seizures'? | [
"seizures",
"seizure",
"convulsions",
"convulsion",
"convulsive seizures"
] | [
"seizure disorders",
"seizure disorder",
"epilepsies",
"epilepsy"
] | Given the context 'Oral administration of CBZ as an aqueous suspension every 8 h at a dose of 250 mg/kg was continuously protective against HFDE-induced seizures and was minimally toxic as measured by weight gain over 8 weeks of treatment.', answer the user's query. |
What is the biomedical concept corresponding to 'weight gain'? | [
"gain, weight",
"weight gain",
"weight gains",
"gains, weight"
] | [
"body weight change",
"body weight changes",
"weight change, body",
"changes, body weight"
] | Given the context 'Oral administration of CBZ as an aqueous suspension every 8 h at a dose of 250 mg/kg was continuously protective against HFDE-induced seizures and was minimally toxic as measured by weight gain over 8 weeks of treatment.', answer the user's query. |
What is the biomedical concept corresponding to 'tachycardia'? | [
"tachycardia",
"tachycardias",
"tachyarrhythmias",
"tachyarrhythmia"
] | [
"tachycardia, supraventricular",
"tachycardia, ventricular",
"tachycardias, supraventricular",
"ventricular tachycardia"
] | Given the context 'Mean arterial pressure (as a percentage of control +/- SEM) during randomized infusions of 0.03, 0.1, 0.3, or 1.0 microgram/kg/min was 99 +/- 1, 95 +/- 1 (p less than 0.05), 93 +/- 1 (p less than 0.01), or 79 +/- 6% (p less than 0.001), respectively, but no tachycardia and no augmentation of the norepinephrine release rate (up to 0.3 microgram/kg/min) were observed, which is in contrast to comparable hypotension induced by hydralazine or nitroglycerin.', answer the user's query. |
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