instruction stringlengths 155 1.76k | input stringlengths 253 769 | response stringclasses 1 value |
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<Instruct>: Given the context 'Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects
Abstract
Background
Congenital cardiovascular diseases are the most common form of birth defects in humans.', select the correct biomedical concept corresponding to 'humans'. Answer using one of the provided options. | <Options>: A: nocardiopsis sp. yim 92628
B: tapinoma nigerrimum
C: salmonella enterica subsp. enterica serovar anatum str. atcc baa-1592 (salmonella enterica subsp. enterica serovar anatum strain atcc baa-1592) (aka salmonella enterica subsp. enterica serovar anatum str. atcc baa-1592)
D: leucoagaricus sp. vellinga 2457
E: phlomis cypria var. occidentalis
F: calathus opaculus
G: leucoagaricus sp. vellinga 2561
H: atheriniformes sp. bold:aac9977
I: phlomis cypria
J: viola sp. 'ash vale blue'
K: None of the above. | K |
<Instruct>: Given the context 'Results
We deleted the TGF-β type I receptor Alk5 specifically in the mouse neural crest cell lineage.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: uncultured organism meddcm-oct-s08-c1656
B: influenza b virus (b/india/d0811473/2008)
C: gateway binary vector r4pgwb404
D: bacterium enrichment culture clone alo1_glfrudd03gfxmd
E: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
F: arthrobacter sp. rhf50
G: gateway binary vector r4pgwb401
H: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
I: gomphina melanegis (aka macridiscus melanaegis)
J: arthrobacter sp. rhf34
K: None of the above. | K |
<Instruct>: Given the context 'Mice deficient in TGF-β2 display fourth aortic arch artery defects [7], while neural crest cell specific abrogation of TGF-β type II receptor (Tgfbr2) results in interruption of the aortic arch and PTA [8,9].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb401
B: uncultured organism meddcm-oct-s08-c1656
C: trebouxia corticola
D: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
E: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
F: bacterium enrichment culture clone alo1_glfrudd03g65nh
G: bacterium enrichment culture clone alo1_glfrudd03gfyx0
H: gomphina melanegis (aka macridiscus melanaegis)
I: arthrobacter sp. rhf34
J: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
K: None of the above. | K |
<Instruct>: Given the context 'To determine, whether ALK5 would also mediate unique non-redundant signaling events in cardiac neural crest cells, we focused on cardiac and pharyngeal phenotypes of mouse embryos lacking Alk5 specifically in neural crest cells.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo132-2/2011/jp
B: arthrobacter sp. rhf50
C: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
D: arthrobacter sp. rhf34
E: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
F: uncultured organism meddcm-oct-s08-c1656
G: norovirus hu/gii/miyagi/geo130-3/2011/jp
H: influenza b virus (b/india/d0811473/2008)
I: paenibacillus sp. pksw2
J: bacterium enrichment culture clone alo1_glfrudd03g65nh
K: None of the above. | K |
<Instruct>: Given the context 'Results
Persistent truncus arteriosus and abnormal large vessels in mice lacking Alk5 in cardiac NCCs
To inactivate Alk5 in cardiac NCCs, mice homozygous for the floxed Alk5 allele (Alk5Flox/Flox)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfyx0
B: uncultured organism meddcm-oct-s08-c1656
C: bacterium enrichment culture clone alo1_glfrudd03gfxt0
D: gateway binary vector r4pgwb404
E: bacterium enrichment culture clone alo1_glfrudd03g65nh
F: norovirus hu/gii/miyagi/geo130-3/2011/jp
G: arthrobacter sp. rhf34
H: paenibacillus sp. pksw2
I: gateway binary vector r4pgwb401
J: arthrobacter sp. rhf50
K: None of the above. | K |
<Instruct>: Given the context 'Results
Persistent truncus arteriosus and abnormal large vessels in mice lacking Alk5 in cardiac NCCs
To inactivate Alk5 in cardiac NCCs, mice homozygous for the floxed Alk5 allele (Alk5Flox/Flox)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo130-3/2011/jp
B: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
C: plethodon shermani stejneger, 1906 (aka plethodon shermani)
D: bacterium enrichment culture clone alo1_glfrudd03gfxt0
E: arthrobacter sp. rhf34
F: trebouxia corticola
G: arthrobacter sp. rhf50
H: bacterium enrichment culture clone alo1_glfrudd03gfxmd
I: gateway binary vector r4pgwb401
J: influenza b virus (b/india/d0811473/2008)
K: None of the above. | K |
<Instruct>: Given the context '[21] were crossed with transgenic Wnt1-Cre mice [22], which were also heterozygous for the Alk5 knockout allele (Alk5KO) allele.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo131-1/2011/jp
B: bacterium enrichment culture clone alo1_glfrudd03gfyx0
C: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
D: gateway binary vector r4pgwb401
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: arthrobacter sp. rhf34
G: bacterium enrichment culture clone alo1_glfrudd03g65nh
H: uncultured organism meddcm-oct-s08-c1656
I: arthrobacter sp. rhf50
J: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
K: None of the above. | K |
<Instruct>: Given the context 'The resulting mice heterozygous for the Alk5Flox and Alk5KO alleles, which also carried the Wnt1-Cre transgene, had the Alk5 gene specifically inactivated in NCCs (herein termed Alk5/Wnt1-Cre), while the littermates with remaining allelic combinations were phenotypically normal and served as controls (Alk5Flox/+, Alk5KO/+; Wnt1-Cre).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo131-1/2011/jp
B: arthrobacter sp. rhf34
C: gateway binary vector r4pgwb401
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: bacterium enrichment culture clone alo1_glfrudd03gfxt0
F: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
G: gateway binary vector r4pgwb404
H: gomphina melanegis (aka macridiscus melanaegis)
I: bacterium enrichment culture clone alo1_glfrudd03gfxmd
J: arthrobacter sp. rhf50
K: None of the above. | K |
<Instruct>: Given the context 'Briefly, Alk5Flox/Flox mice were crossed with the ROSA26 Cre reporter mice, and subsequently Alk5Flox/Flox;R26R(+/+)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: arthrobacter sp. rhf34
B: arthrobacter sp. rhf50
C: gomphina melanaegis (aka macridiscus melanaegis)
D: plethodon shermani stejneger, 1906 (aka plethodon shermani)
E: gateway binary vector r4pgwb404
F: norovirus hu/gii/miyagi/geo130-3/2011/jp
G: bacterium enrichment culture clone alo1_glfrudd03g65nh
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: gateway binary vector r4pgwb401
J: bacterium enrichment culture clone alo1_glfrudd03gfxt0
K: None of the above. | K |
<Instruct>: Given the context 'Briefly, Alk5Flox/Flox mice were crossed with the ROSA26 Cre reporter mice, and subsequently Alk5Flox/Flox;R26R(+/+)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
B: bacterium enrichment culture clone alo1_glfrudd03g65nh
C: arthrobacter sp. rhf34
D: gomphina melanaegis (aka macridiscus melanaegis)
E: gateway binary vector r4pgwb404
F: norovirus hu/gii/miyagi/geo131-1/2011/jp
G: trebouxia corticola
H: uncultured organism meddcm-oct-s08-c1656
I: norovirus hu/gii/miyagi/geo130-3/2011/jp
J: bacterium enrichment culture clone alo1_glfrudd03gfyx0
K: None of the above. | K |
<Instruct>: Given the context 'While Tgfbr2/Wnt1-Cre mutants as well as mice deficient in Tgf-β2 display the PTA type A4 (truncus arteriosus with interrupted aortic arch', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: paenibacillus sp. pksw2
B: bacterium enrichment culture clone alo1_glfrudd03g65nh
C: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: gateway binary vector r4pgwb401
F: influenza b virus (b/india/d0811473/2008)
G: bacterium enrichment culture clone alo1_glfrudd03gfyx0
H: norovirus hu/gii/miyagi/geo130-3/2011/jp
I: norovirus hu/gii/miyagi/geo131-1/2011/jp
J: gomphina melanegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'Although relevant Gdfs 8, 9 11 and 15 are not expressed in the developing heart, nor do the mice deficient in these Gdfs display developmental cardiac defects, we cannot exclude the possibility that circulating GDFs, perhaps in concert with TGF-βs may contribute to NCC survival during cardiac and pharyngeal morphogenesis.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfyx0
B: bacterium enrichment culture clone alo1_glfrudd03g65nh
C: arthrobacter sp. rhf34
D: gateway binary vector r4pgwb404
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: gateway binary vector r4pgwb401
G: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
H: gomphina melanaegis (aka macridiscus melanaegis)
I: bacterium enrichment culture clone alo1_glfrudd03gfxt0
J: arthrobacter sp. rhf50
K: None of the above. | K |
<Instruct>: Given the context 'Moreover, a recent in vivo study suggested that mice lacking Tgfbr2 in CNCCs display defective NCC differentiation into αSMA-positive cells in the AP septum [9], although this result was later disputed by another study', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb401
B: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
C: bacterium enrichment culture clone alo1_glfrudd03gfxmd
D: gateway binary vector r4pgwb404
E: gomphina melanegis (aka macridiscus melanaegis)
F: influenza b virus (b/india/d0811473/2008)
G: bacterium enrichment culture clone alo1_glfrudd03gfyx0
H: norovirus hu/gii/miyagi/geo130-3/2011/jp
I: paenibacillus sp. pksw2
J: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
K: None of the above. | K |
<Instruct>: Given the context 'Since we could not detect appropriate rotation of the OFT in neural crest-specific mutants of Alk5 or Alk2, it appears that cells derived from the NC, as well as those from the SHF, are mutually required for proper OFT rotation in mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: trebouxia corticola
B: gateway binary vector r4pgwb401
C: gomphina melanaegis (aka macridiscus melanaegis)
D: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
E: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: plethodon shermani stejneger, 1906 (aka plethodon shermani)
H: paenibacillus sp. pksw2
I: bacterium enrichment culture clone alo1_glfrudd03gfyx0
J: norovirus hu/gii/miyagi/geo131-1/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Conclusion
In this study, we have deleted the TGF-β type I receptor (Alk5) gene specifically in the mouse neural crest (NC) cell lineage.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: uncultured organism meddcm-oct-s08-c1656
B: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
C: norovirus hu/gii/miyagi/geo132-2/2011/jp
D: gomphina melanaegis (aka macridiscus melanaegis)
E: influenza b virus (b/india/d0811473/2008)
F: gateway binary vector r4pgwb401
G: gateway binary vector r4pgwb404
H: trebouxia corticola
I: arthrobacter sp. rhf50
J: norovirus hu/gii/miyagi/geo131-1/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Methods
Alk5/Wnt1Cre mice
Alk5 (and Alk2) mutant and control embryos were generated by mating Alk5ko/+(Alk2ko/+)/Wnt1-Cre male mice with females homozygous for the Alk5flox (Alk2flox) allele and the R26R reporter[12,19].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: uncultured organism meddcm-oct-s08-c1656
B: gomphina melanegis (aka macridiscus melanaegis)
C: bacterium enrichment culture clone alo1_glfrudd03gfxmd
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: bacterium enrichment culture clone alo1_glfrudd03gfyx0
F: influenza b virus (b/india/d0811473/2008)
G: gateway binary vector r4pgwb401
H: gateway binary vector r4pgwb404
I: norovirus hu/gii/miyagi/geo130-3/2011/jp
J: bacterium enrichment culture clone alo1_glfrudd03gfxt0
K: None of the above. | K |
<Instruct>: Given the context 'Methods
Alk5/Wnt1Cre mice
Alk5 (and Alk2) mutant and control embryos were generated by mating Alk5ko/+(Alk2ko/+)/Wnt1-Cre male mice with females homozygous for the Alk5flox (Alk2flox) allele and the R26R reporter[12,19].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
B: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
C: plethodon shermani stejneger, 1906 (aka plethodon shermani)
D: bacterium enrichment culture clone alo1_glfrudd03gfxt0
E: bacterium enrichment culture clone alo1_glfrudd03gfxmd
F: influenza b virus (b/india/d0811473/2008)
G: gateway binary vector r4pgwb401
H: paenibacillus sp. pksw2
I: bacterium enrichment culture clone alo1_glfrudd03g65nh
J: gomphina melanegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'Wnt1-Cre mice were kindly provided by A. McMahon (Harvard University) and R26R reporter mice were obtained from the Jackson laboratories.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfxmd
B: gateway binary vector r4pgwb404
C: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
D: gomphina melanaegis (aka macridiscus melanaegis)
E: bacterium enrichment culture clone alo1_glfrudd03gfyx0
F: norovirus hu/gii/miyagi/geo131-1/2011/jp
G: bacterium enrichment culture clone alo1_glfrudd03g65nh
H: arthrobacter sp. rhf50
I: bacterium enrichment culture clone alo1_glfrudd03gfxt0
J: gateway binary vector r4pgwb401
K: None of the above. | K |
<Instruct>: Given the context 'Wnt1-Cre mice were kindly provided by A. McMahon (Harvard University) and R26R reporter mice were obtained from the Jackson laboratories.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: plethodon shermani stejneger, 1906 (aka plethodon shermani)
B: uncultured organism meddcm-oct-s08-c1656
C: trebouxia corticola
D: paenibacillus sp. pksw2
E: bacterium enrichment culture clone alo1_glfrudd03gfxt0
F: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
G: arthrobacter sp. rhf34
H: influenza b virus (b/india/d0811473/2008)
I: gateway binary vector r4pgwb401
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'All studies were carried out at the Animal Care Facility of the Saban Research Institute of Childrens Hospital Los Angeles in accordance with institutional guidelines.
', select the correct biomedical concept corresponding to 'animal'. Answer using one of the provided options. | <Options>: A: coleoptera sp. bold:aao4649
B: viola sp. 'ash vale blue'
C: bathysiphon sp. isolate 3987
D: coleoptera sp. bold:aao4638
E: lepidoptera sp. bold:aae2369
F: bodomorpha sp. hfcc 927
G: coleoptera sp. bold:aao4639
H: coleoptera sp. bold:aao4621
I: elphidium cf. williamsoni
J: passiflora ciliata (passiflora foetida var. ciliata (aiton) mast.) (aka passiflora ciliata)
K: None of the above. | K |
<Instruct>: Given the context 'Timed mataings
Mice were mated during the dark period of the controlled light cycle; presence of vaginal plugs was designated as day 0 hour 0.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfyx0
B: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
C: bacterium enrichment culture clone alo1_glfrudd03gfxt0
D: bacterium enrichment culture clone alo1_glfrudd03g65nh
E: gateway binary vector r4pgwb401
F: uncultured organism meddcm-oct-s08-c1656
G: gateway binary vector r4pgwb404
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: norovirus hu/gii/miyagi/geo131-1/2011/jp
J: bacterium enrichment culture clone alo1_glfrudd03gfxmd
K: None of the above. | K |
<Instruct>: Given the context 'Authors' contributions
J.W. did most of the mouse dissections and analyses, A.N. did some of the histological analyses, J.L. generated the Alk5FXFXmice, M.D. did some of the expression analyses, H.M.S. participated in design and provided the Tgfbr2 mutant embryos and V.K. generated the Alk2FXFX mice, designed and supervised the experiments and wrote the manuscript.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo132-2/2011/jp
B: uncultured organism meddcm-oct-s08-c1656
C: gomphina melanaegis (aka macridiscus melanaegis)
D: bacterium enrichment culture clone alo1_glfrudd03gfxmd
E: bacterium enrichment culture clone alo1_glfrudd03gfxt0
F: trebouxia corticola
G: gateway binary vector r4pgwb404
H: gateway binary vector r4pgwb401
I: norovirus hu/gii/miyagi/geo131-1/2011/jp
J: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
K: None of the above. | K |
<Instruct>: Given the context 'Authors' contributions
J.W. did most of the mouse dissections and analyses, A.N. did some of the histological analyses, J.L. generated the Alk5FXFXmice, M.D. did some of the expression analyses, H.M.S. participated in design and provided the Tgfbr2 mutant embryos and V.K. generated the Alk2FXFX mice, designed and supervised the experiments and wrote the manuscript.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb404
B: norovirus hu/gii/miyagi/geo131-1/2011/jp
C: norovirus hu/gii/miyagi/geo130-3/2011/jp
D: arthrobacter sp. rhf34
E: gateway binary vector r4pgwb401
F: arthrobacter sp. rhf50
G: trebouxia corticola
H: bacterium enrichment culture clone alo1_glfrudd03gfyx0
I: bacterium enrichment culture clone alo1_glfrudd03gfxt0
J: plethodon shermani stejneger, 1906 (aka plethodon shermani)
K: None of the above. | K |
<Instruct>: Given the context 'Acknowledgements
We thank A. McMahon for providing the Wnt1-Cre mouse line, N. Manley for the PTH probe and B. Choudhary for Tgfbr2/Wnt1-Cre embryos.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03g65nh
B: gomphina melanegis (aka macridiscus melanaegis)
C: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
D: bacterium enrichment culture clone alo1_glfrudd03gfyx0
E: arthrobacter sp. rhf34
F: paenibacillus sp. pksw2
G: norovirus hu/gii/miyagi/geo130-3/2011/jp
H: arthrobacter sp. rhf50
I: norovirus hu/gii/miyagi/geo132-2/2011/jp
J: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
K: None of the above. | K |
<Instruct>: Given the context 'RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses
Abstract
In recent years, tremendous insight has been gained on p53 regulation by targeting mutations at the p53 locus using homologous recombination in ES cells to generate mutant mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: uncultured organism meddcm-oct-s08-c1656
B: norovirus hu/gii/miyagi/geo130-3/2011/jp
C: bacterium enrichment culture clone alo1_glfrudd03gfyx0
D: trebouxia corticola
E: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: paenibacillus sp. pksw2
H: bacterium enrichment culture clone alo1_glfrudd03gfxmd
I: bacterium enrichment culture clone alo1_glfrudd03g65nh
J: arthrobacter sp. rhf34
K: None of the above. | K |
<Instruct>: Given the context 'Our approach enables efficient targeting in ES cells to facilitate the production of mutant mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: plethodon shermani stejneger, 1906 (aka plethodon shermani)
B: arthrobacter sp. rhf50
C: trebouxia corticola
D: bacterium enrichment culture clone alo1_glfrudd03g65nh
E: paenibacillus sp. pksw2
F: norovirus hu/gii/miyagi/geo131-1/2011/jp
G: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
H: bacterium enrichment culture clone alo1_glfrudd03gfxmd
I: gateway binary vector r4pgwb401
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'RMCE-ASAP combines inverted heterologous recombinase target sites, a positive/negative selection marker that preserves the germline capacity of ES cells, and the power of mouse genetics.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfxt0
B: norovirus hu/gii/miyagi/geo130-3/2011/jp
C: trebouxia corticola
D: gateway binary vector r4pgwb404
E: gateway binary vector r4pgwb401
F: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
G: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
H: influenza b virus (b/india/d0811473/2008)
I: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
J: uncultured organism meddcm-oct-s08-c1656
K: None of the above. | K |
<Instruct>: Given the context 'In recent years, some of these models were tested in vivo by targeting subtle mutations at the p53 locus using homologous recombination in embryonic stem (ES) cells to generate mutant mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
B: paenibacillus sp. pksw2
C: arthrobacter sp. rhf50
D: norovirus hu/gii/miyagi/geo131-1/2011/jp
E: bacterium enrichment culture clone alo1_glfrudd03gfxt0
F: plethodon shermani stejneger, 1906 (aka plethodon shermani)
G: bacterium enrichment culture clone alo1_glfrudd03gfxmd
H: norovirus hu/gii/miyagi/geo130-3/2011/jp
I: gateway binary vector r4pgwb404
J: gomphina melanegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'However, using homologous recombination in ES cells to generate mutant mice is an inefficient, slow and expensive method because (i) homologous recombination typically occurs at low frequency in ES cells, requiring sophisticated selection schemes and screening of hundreds of clones to identify the desired mutant; (ii) large (15–20 kb) plasmids, often difficult to clone, are required to increase targeting efficiency and (iii) breeding mice to homozygosity and housing a mouse colony generate further delays and costs.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gomphina melanaegis (aka macridiscus melanaegis)
B: norovirus hu/gii/miyagi/geo131-1/2011/jp
C: uncultured organism meddcm-oct-s08-c1656
D: gateway binary vector r4pgwb404
E: bacterium enrichment culture clone alo1_glfrudd03gfxt0
F: bacterium enrichment culture clone alo1_glfrudd03gfyx0
G: arthrobacter sp. rhf34
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: paenibacillus sp. pksw2
J: influenza b virus (b/india/d0811473/2008)
K: None of the above. | K |
<Instruct>: Given the context 'However, using homologous recombination in ES cells to generate mutant mice is an inefficient, slow and expensive method because (i) homologous recombination typically occurs at low frequency in ES cells, requiring sophisticated selection schemes and screening of hundreds of clones to identify the desired mutant; (ii) large (15–20 kb) plasmids, often difficult to clone, are required to increase targeting efficiency and (iii) breeding mice to homozygosity and housing a mouse colony generate further delays and costs.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
B: uncultured organism meddcm-oct-s08-c1656
C: influenza b virus (b/india/d0811473/2008)
D: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
E: gomphina melanegis (aka macridiscus melanaegis)
F: bacterium enrichment culture clone alo1_glfrudd03gfyx0
G: norovirus hu/gii/miyagi/geo130-3/2011/jp
H: paenibacillus sp. pksw2
I: arthrobacter sp. rhf34
J: bacterium enrichment culture clone alo1_glfrudd03gfxt0
K: None of the above. | K |
<Instruct>: Given the context 'However, using homologous recombination in ES cells to generate mutant mice is an inefficient, slow and expensive method because (i) homologous recombination typically occurs at low frequency in ES cells, requiring sophisticated selection schemes and screening of hundreds of clones to identify the desired mutant; (ii) large (15–20 kb) plasmids, often difficult to clone, are required to increase targeting efficiency and (iii) breeding mice to homozygosity and housing a mouse colony generate further delays and costs.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
B: gomphina melanegis (aka macridiscus melanaegis)
C: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
D: bacterium enrichment culture clone alo1_glfrudd03g65nh
E: bacterium enrichment culture clone alo1_glfrudd03gfyx0
F: arthrobacter sp. rhf50
G: norovirus hu/gii/miyagi/geo132-2/2011/jp
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: norovirus hu/gii/miyagi/geo130-3/2011/jp
J: arthrobacter sp. rhf34
K: None of the above. | K |
<Instruct>: Given the context 'Indeed, siRNAs in fibroblasts often provide a faster read-out than equivalent gene knock-outs in animals (6).', select the correct biomedical concept corresponding to 'animals'. Answer using one of the provided options. | <Options>: A: viola suavis
B: bathysiphon sp. isolate 3987
C: lepidoptera sp. bold:aae2369
D: parmelia austerodes (aka hypogymnia austerodes)
E: hypogymnia antarctica (parmelia antarctica) (aka hypogymnia antarctica)
F: lepidoptera sp. bold:aae2368
G: passiflora foetida var. ciliata (aiton) mast. (aka passiflora ciliata)
H: opetiinae
I: viola sp. 'ash vale blue'
J: ahnfeltiales
K: None of the above. | K |
<Instruct>: Given the context 'Previously, technical difficulties have prevented RMCE from being applied routinely to generate mutant mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
B: paenibacillus sp. pksw2
C: gateway binary vector r4pgwb401
D: trebouxia corticola
E: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
F: plethodon shermani stejneger, 1906 (aka plethodon shermani)
G: bacterium enrichment culture clone alo1_glfrudd03gfxmd
H: bacterium enrichment culture clone alo1_glfrudd03g65nh
I: arthrobacter sp. rhf50
J: uncultured organism meddcm-oct-s08-c1656
K: None of the above. | K |
<Instruct>: Given the context 'Only a few mutant mice generated by RMCE in ES cells have been reported, but the RMCE systematically introduced a selectable marker (15–17), or, when tested without an incoming marker, proved inefficient (12).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb401
B: uncultured organism meddcm-oct-s08-c1656
C: norovirus hu/gii/miyagi/geo131-1/2011/jp
D: influenza b virus (b/india/d0811473/2008)
E: trebouxia corticola
F: paenibacillus sp. pksw2
G: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
H: gomphina melanaegis (aka macridiscus melanaegis)
I: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
J: bacterium enrichment culture clone alo1_glfrudd03gfxmd
K: None of the above. | K |
<Instruct>: Given the context 'A recent report disclosed an additional problem: the Hygromycin–Thymidine Kinase fusion gene used most frequently for positive/negative selection in RMCE, leads to mouse sterility, so that exchanges can only be performed in ES cells (16).
', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: influenza b virus (b/india/d0811473/2008)
B: gomphina melanaegis (aka macridiscus melanaegis)
C: bacterium enrichment culture clone alo1_glfrudd03gfxt0
D: trebouxia corticola
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: paenibacillus sp. pksw2
G: gateway binary vector r4pgwb404
H: bacterium enrichment culture clone alo1_glfrudd03gfxmd
I: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
J: arthrobacter sp. rhf34
K: None of the above. | K |
<Instruct>: Given the context 'The RMCE strategy presented here relies on the integrated use of inverted heterologous loxP sites, a positive/negative selection marker that preserves the germline capacity of ES cells, and the power of mouse genetics to expedite phenotypic analyses.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: uncultured organism meddcm-oct-s08-c1656
B: gateway binary vector r4pgwb401
C: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
D: trebouxia corticola
E: bacterium enrichment culture clone alo1_glfrudd03gfxt0
F: gomphina melanaegis (aka macridiscus melanaegis)
G: norovirus hu/gii/miyagi/geo131-1/2011/jp
H: influenza b virus (b/india/d0811473/2008)
I: gateway binary vector r4pgwb404
J: paenibacillus sp. pksw2
K: None of the above. | K |
<Instruct>: Given the context 'We show that our approach enables efficient targeting of marker-free mutations at the p53 locus in ES cells to generate mutant mice, but more importantly, it is Adapted for targeting in Somatic cells to Accelerate Phenotyping (ASAP).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfxmd
B: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
C: gateway binary vector r4pgwb401
D: gateway binary vector r4pgwb404
E: bacterium enrichment culture clone alo1_glfrudd03g65nh
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: arthrobacter sp. rhf34
H: trebouxia corticola
I: paenibacillus sp. pksw2
J: influenza b virus (b/india/d0811473/2008)
K: None of the above. | K |
<Instruct>: Given the context 'Performing RMCE in ES cells
A total of 8 × 105 p53RMCE/+ ES cells were grown without puromycin for 12 h, electroporated with 15 μg CMV-Cre plasmid (pOG231) and 200 μg of the exchange construct, and plated in T25 flasks at 105 cells per flask.', select the correct biomedical concept corresponding to 'cmv'. Answer using one of the provided options. | <Options>: A: wild marrow (aka cucurbita pepo var. texana)
B: bacterium enrichment culture clone alo1_glfrudd03fys4z
C: influenza a virus (a/cambodia/nhrca0004/2009(h3n2)) (aka influenza a virus (a/cambodia/nhrcc00004/2009(h3n2)))
D: pachyanthus monopleurus urb. (aka pachyanthus monopleurus)
E: bacterium enrichment culture clone alo1_glfrudd03fys9i
F: lepidoptera sp. bold:aaq3463
G: burkholderia sp. iiia_4a
H: delftia sp. pp4_s6
I: spinycheek lanternfish (aka benthosema fibulatum)
J: influenza a virus (a/american wigeon/california/8141/2008(h6n1))
K: None of the above. | K |
<Instruct>: Given the context 'Secondary antibodies used include peroxidase-conjugated goat anti-mouse IgG and anti-rabbit IgG (Pierce).', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: trebouxia corticola
B: arthrobacter sp. rhf34
C: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
D: influenza b virus (b/india/d0811473/2008)
E: bacterium enrichment culture clone alo1_glfrudd03gfyx0
F: norovirus hu/gii/miyagi/geo132-2/2011/jp
G: uncultured organism meddcm-oct-s08-c1656
H: gomphina melanaegis (aka macridiscus melanaegis)
I: norovirus hu/gii/miyagi/geo131-1/2011/jp
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Secondary antibodies used include peroxidase-conjugated goat anti-mouse IgG and anti-rabbit IgG (Pierce).', select the correct biomedical concept corresponding to 'rabbit'. Answer using one of the provided options. | <Options>: A: bacillus sp. zk4786
B: lophodermium gramineum (hysterium arundinaceum var. gramineum) (aka lophodermium gramineum)
C: sechellophryne
D: comamonas sp. 4d-w-18
E: thysanoptera sp. bold:aan9111
F: codium intertextum (codium intertextum f.s. collins & hervey) (aka codium intertextum)
G: cryptonanus sp. ssl-2010
H: mycobacterium moriokaense (mycobacterium moriokaense tsukamura et al. 1986) (aka mycobacterium moriokaense)
I: alteromonadales bacterium hot4b6
J: mortierella sp. tdmort1
K: None of the above. | K |
<Instruct>: Given the context 'Secondary antibodies used include peroxidase-conjugated goat anti-mouse IgG and anti-rabbit IgG (Pierce).', select the correct biomedical concept corresponding to 'goat'. Answer using one of the provided options. | <Options>: A: japanese palolo (aka tylorrhynchus heterochaetus)
B: euryalida sp. bold:aac7432
C: sapovirus llobregat river/site5_2/mar2009/es
D: euryalida sp. bold:aac7433
E: haplotaxida sp. bold:aaa2168
F: streptomyces lavendulocolor (kuchaeva et al. 1961) pridham 1970 (aka streptomyces lavendulocolor)
G: enhydrobacter sp. itcr12
H: pollanisus sp. anic5
I: halocyprida sp. bold:aaj6916
J: avian sarcoma virus (strain 17) (aka avian sarcoma virus 17)
K: None of the above. | K |
<Instruct>: Given the context 'This, together with the observation that p53 levels decrease during mouse embryogenesis (19), suggested an explanation for the observed lack of pregnancies: we speculate that the high levels of p53GFP in the ES cells injected into blastocysts might have prevented normal embryonic development once these cells began to differentiate and the p53 pathway became functional.
', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: arthrobacter sp. rhf34
B: gateway binary vector r4pgwb404
C: bacterium enrichment culture clone alo1_glfrudd03gfxt0
D: bacterium enrichment culture clone alo1_glfrudd03gfxmd
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
G: norovirus hu/gii/miyagi/geo132-2/2011/jp
H: gomphina melanegis (aka macridiscus melanaegis)
I: bacterium enrichment culture clone alo1_glfrudd03gfyx0
J: paenibacillus sp. pksw2
K: None of the above. | K |
<Instruct>: Given the context 'We next determined whether p53+/ΔPGFP ES cells could generate chimeric mice and transmit the modified allele through the germline.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo130-3/2011/jp
B: bacterium enrichment culture clone alo1_glfrudd03gfyx0
C: bacterium enrichment culture clone alo1_glfrudd03g65nh
D: plethodon shermani stejneger, 1906 (aka plethodon shermani)
E: gateway binary vector r4pgwb401
F: trebouxia corticola
G: influenza b virus (b/india/d0811473/2008)
H: gomphina melanegis (aka macridiscus melanaegis)
I: bacterium enrichment culture clone alo1_glfrudd03gfxmd
J: arthrobacter sp. rhf50
K: None of the above. | K |
<Instruct>: Given the context 'Two p53+/ΔPGFP ES cell clones were injected into blastocysts and highly chimeric (>80%) mice were obtained.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb404
B: arthrobacter sp. rhf34
C: bacterium enrichment culture clone alo1_glfrudd03g65nh
D: influenza b virus (b/india/d0811473/2008)
E: bacterium enrichment culture clone alo1_glfrudd03gfxmd
F: norovirus hu/gii/miyagi/geo130-3/2011/jp
G: norovirus hu/gii/miyagi/geo131-1/2011/jp
H: gomphina melanegis (aka macridiscus melanaegis)
I: arthrobacter sp. rhf50
J: paenibacillus sp. pksw2
K: None of the above. | K |
<Instruct>: Given the context 'Heterozygote pups were recovered from the mating the chimeras with WT mice (Figure 3C).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: arthrobacter sp. rhf50
B: bacterium enrichment culture clone alo1_glfrudd03gfxt0
C: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: plethodon shermani stejneger, 1906 (aka plethodon shermani)
F: bacterium enrichment culture clone alo1_glfrudd03gfyx0
G: gateway binary vector r4pgwb404
H: influenza b virus (b/india/d0811473/2008)
I: arthrobacter sp. rhf34
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'We first verified that the RMCE-ready p53 locus (p53RMCE) could be transmitted through the germline by mating p53RMCE/+ chimeras with p53+/− mice (20) (Figure 4).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: paenibacillus sp. pksw2
B: gateway binary vector r4pgwb404
C: bacterium enrichment culture clone alo1_glfrudd03g65nh
D: norovirus hu/gii/miyagi/geo130-3/2011/jp
E: norovirus hu/gii/miyagi/geo131-1/2011/jp
F: arthrobacter sp. rhf50
G: influenza b virus (b/india/d0811473/2008)
H: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
I: trebouxia corticola
J: arthrobacter sp. rhf34
K: None of the above. | K |
<Instruct>: Given the context 'These data report the development and implementation of an improved RMCE approach that enables efficient allele modification in ES cells to generate mice and in heterozygous MEFs to accelerate phenotypic analyses.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb404
B: norovirus hu/gii/miyagi/geo131-1/2011/jp
C: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
D: influenza b virus (b/india/d0811473/2008)
E: gomphina melanegis (aka macridiscus melanaegis)
F: arthrobacter sp. rhf34
G: trebouxia corticola
H: plethodon shermani stejneger, 1906 (aka plethodon shermani)
I: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
J: bacterium enrichment culture clone alo1_glfrudd03gfxmd
K: None of the above. | K |
<Instruct>: Given the context 'These characteristics should make RMCE-ASAP a robust and general technology for analysis of mammalian genes under conditions that preserve normal control mechanisms in different tissues.', select the correct biomedical concept corresponding to 'mammalian'. Answer using one of the provided options. | <Options>: A: xenopus sp. amnh17260 (xenopus sp. gvdk150-09) (aka xenopus sp. amnh17260)
B: fusarium sp. s33
C: euploea tulliolus
D: viola suavis
E: xylophanes germen
F: lepidoptera sp. bold:aae2369
G: xenopus sp. amnh17261 (xenopus sp. gvdk151-09) (aka xenopus sp. amnh17261)
H: mytilina ventralis var. brevispina (aka mytilina ventralis brevispina)
I: viola sp. 'ash vale blue'
J: ahnfeltiales
K: None of the above. | K |
<Instruct>: Given the context 'An exchange is performed in these cells by co-transfecting a Cre expression plasmid and a marker-free plasmid with a floxed mutant GOI (green box: mutated exon), to produce a mutant mouse (path A).', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo132-2/2011/jp
B: bacterium enrichment culture clone alo1_glfrudd03gfxmd
C: paenibacillus sp. pksw2
D: gateway binary vector r4pgwb401
E: arthrobacter sp. rhf34
F: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
G: bacterium enrichment culture clone alo1_glfrudd03gfxt0
H: arthrobacter sp. rhf50
I: trebouxia corticola
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Importantly RMCE-ASAP incorporates two major improvements over classical RMCE (path B): (i) the positive/negative selection cassette does not prevent germline transmission, so that RMCE-ready mice can be obtained; (ii) the selection cassette does not replace, but rather lies downstream of the GOI.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo131-1/2011/jp
B: paenibacillus sp. pksw2
C: gateway binary vector r4pgwb401
D: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
E: bacterium enrichment culture clone alo1_glfrudd03gfyx0
F: arthrobacter sp. rhf34
G: plethodon shermani stejneger, 1906 (aka plethodon shermani)
H: gateway binary vector r4pgwb404
I: norovirus hu/gii/miyagi/geo130-3/2011/jp
J: bacterium enrichment culture clone alo1_glfrudd03gfxt0
K: None of the above. | K |
<Instruct>: Given the context 'Hence, after breeding the RMCE-ready mouse with mice heterozygotes for the GOI, somatic cells with an RMCE-ready locus and a WT or KO allele can be recovered [e.g. RMCE/+ and RMCE/− mouse embryonic fibroblasts (MEFs)].', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb404
B: gateway binary vector r4pgwb401
C: trebouxia corticola
D: paenibacillus sp. pksw2
E: bacterium enrichment culture clone alo1_glfrudd03gfxt0
F: norovirus hu/gii/miyagi/geo131-1/2011/jp
G: gomphina melanegis (aka macridiscus melanaegis)
H: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
I: arthrobacter sp. rhf34
J: uncultured organism meddcm-oct-s08-c1656
K: None of the above. | K |
<Instruct>: Given the context 'Hence, after breeding the RMCE-ready mouse with mice heterozygotes for the GOI, somatic cells with an RMCE-ready locus and a WT or KO allele can be recovered [e.g. RMCE/+ and RMCE/− mouse embryonic fibroblasts (MEFs)].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: uncultured organism meddcm-oct-s08-c1656
B: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
C: bacterium enrichment culture clone alo1_glfrudd03gfxmd
D: gateway binary vector r4pgwb404
E: gateway binary vector r4pgwb401
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: trebouxia corticola
H: gomphina melanegis (aka macridiscus melanaegis)
I: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
J: influenza b virus (b/india/d0811473/2008)
K: None of the above. | K |
<Instruct>: Given the context 'Hence, after breeding the RMCE-ready mouse with mice heterozygotes for the GOI, somatic cells with an RMCE-ready locus and a WT or KO allele can be recovered [e.g. RMCE/+ and RMCE/− mouse embryonic fibroblasts (MEFs)].', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
B: bacterium enrichment culture clone alo1_glfrudd03gfxt0
C: gateway binary vector r4pgwb401
D: gateway binary vector r4pgwb404
E: uncultured organism meddcm-oct-s08-c1656
F: bacterium enrichment culture clone alo1_glfrudd03gfxmd
G: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
H: norovirus hu/gii/miyagi/geo131-1/2011/jp
I: bacterium enrichment culture clone alo1_glfrudd03g65nh
J: bacterium enrichment culture clone alo1_glfrudd03gfyx0
K: None of the above. | K |
<Instruct>: Given the context 'DNA of seven littermates (U42–U48), obtained from mating a p53ΔPGFP chimera with a WT mouse, was analyzed by PCR with primers d and e (see B), with DNA from WT, p53+/ΔP and p53ΔP/ΔP MEFs (5) as controls.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: paenibacillus sp. pksw2
B: bacterium enrichment culture clone alo1_glfrudd03g65nh
C: uncultured organism meddcm-oct-s08-c1656
D: trebouxia corticola
E: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
F: bacterium enrichment culture clone alo1_glfrudd03gfxmd
G: bacterium enrichment culture clone alo1_glfrudd03gfxt0
H: influenza b virus (b/india/d0811473/2008)
I: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
J: bacterium enrichment culture clone alo1_glfrudd03gfyx0
K: None of the above. | K |
<Instruct>: Given the context 'U45, a p53+/ΔPGFP mouse, demonstrated transmission of the mutation.
', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: arthrobacter sp. rhf34
B: influenza b virus (b/india/d0811473/2008)
C: arthrobacter sp. rhf50
D: bacterium enrichment culture clone alo1_glfrudd03gfyx0
E: bacterium enrichment culture clone alo1_glfrudd03g65nh
F: gateway binary vector r4pgwb404
G: gateway binary vector r4pgwb401
H: bacterium enrichment culture clone alo1_glfrudd03gfxt0
I: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
J: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
K: None of the above. | K |
<Instruct>: Given the context 'p53RMCE/+ ES cells were injected into blastocysts to generate chimeric mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo131-1/2011/jp
B: norovirus hu/gii/miyagi/geo130-3/2011/jp
C: plethodon shermani stejneger, 1906 (aka plethodon shermani)
D: bacterium enrichment culture clone alo1_glfrudd03gfxt0
E: bacterium enrichment culture clone alo1_glfrudd03gfxmd
F: paenibacillus sp. pksw2
G: trebouxia corticola
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: arthrobacter sp. rhf50
J: bacterium enrichment culture clone alo1_glfrudd03g65nh
K: None of the above. | K |
<Instruct>: Given the context 'Chimeras (>80%) were then mated with p53+/− mice (Taconic) and MEFs were prepared.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: trebouxia corticola
B: gomphina melanegis (aka macridiscus melanaegis)
C: norovirus hu/gii/miyagi/geo131-1/2011/jp
D: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
E: influenza b virus (b/india/d0811473/2008)
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: arthrobacter sp. rhf50
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: uncultured organism meddcm-oct-s08-c1656
J: bacterium enrichment culture clone alo1_glfrudd03g65nh
K: None of the above. | K |
<Instruct>: Given the context 'Each of these three MEF clones was further analyzed (bottom) with primers f and g (left lanes) and h and i (right lanes), routinely used to genotype p53+/− mice (sequences in Materials and Methods).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo131-1/2011/jp
B: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
C: bacterium enrichment culture clone alo1_glfrudd03g65nh
D: influenza b virus (b/india/d0811473/2008)
E: gateway binary vector r4pgwb404
F: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
G: gateway binary vector r4pgwb401
H: uncultured organism meddcm-oct-s08-c1656
I: trebouxia corticola
J: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
K: None of the above. | K |
<Instruct>: Given the context 'Intraocular pressure in genetically distinct mice: an update and strain survey
Abstract
Background
Little is known about genetic factors affecting intraocular pressure (IOP) in mice and other mammals.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo131-1/2011/jp
B: gateway binary vector r4pgwb404
C: bacterium enrichment culture clone alo1_glfrudd03gfyx0
D: trebouxia corticola
E: influenza b virus (b/india/d0811473/2008)
F: bacterium enrichment culture clone alo1_glfrudd03g65nh
G: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
H: paenibacillus sp. pksw2
I: norovirus hu/gii/miyagi/geo130-3/2011/jp
J: arthrobacter sp. rhf50
K: None of the above. | K |
<Instruct>: Given the context 'Intraocular pressure in genetically distinct mice: an update and strain survey
Abstract
Background
Little is known about genetic factors affecting intraocular pressure (IOP) in mice and other mammals.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03g65nh
B: uncultured organism meddcm-oct-s08-c1656
C: bacterium enrichment culture clone alo1_glfrudd03gfyx0
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: gateway binary vector r4pgwb404
G: plethodon shermani stejneger, 1906 (aka plethodon shermani)
H: bacterium enrichment culture clone alo1_glfrudd03gfxt0
I: norovirus hu/gii/miyagi/geo131-1/2011/jp
J: trebouxia corticola
K: None of the above. | K |
<Instruct>: Given the context 'Intraocular pressure in genetically distinct mice: an update and strain survey
Abstract
Background
Little is known about genetic factors affecting intraocular pressure (IOP) in mice and other mammals.', select the correct biomedical concept corresponding to 'mammals'. Answer using one of the provided options. | <Options>: A: viola sp. 'ash vale blue'
B: lepidoptera sp. bold:aae2376
C: brunsvigia gregaria
D: bathysiphon sp. isolate 3987
E: ahnfeltiales
F: ajuga pygmaea
G: ajuga nipponensis
H: euploea tulliolus
I: xenopus sp. amnh17260 (xenopus sp. gvdk150-09) (aka xenopus sp. amnh17260)
J: globobulimina turgida
K: None of the above. | K |
<Instruct>: Given the context 'The purpose of this study was to determine the IOPs of genetically distinct mouse strains, assess the effects of factors such as age, sex and time of day on IOP in specific strain backgrounds, and to assess the effects of specific candidate gene mutations on IOP.
', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
B: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
C: norovirus hu/gii/miyagi/geo130-3/2011/jp
D: norovirus hu/gii/miyagi/geo131-1/2011/jp
E: bacterium enrichment culture clone alo1_glfrudd03g65nh
F: uncultured organism meddcm-oct-s08-c1656
G: gateway binary vector r4pgwb404
H: gomphina melanaegis (aka macridiscus melanaegis)
I: bacterium enrichment culture clone alo1_glfrudd03gfxmd
J: gateway binary vector r4pgwb401
K: None of the above. | K |
<Instruct>: Given the context 'Results
Based on over 30 studied mouse strains, average IOP ranges from approximately 10 to 20 mmHg.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfxmd
B: bacterium enrichment culture clone alo1_glfrudd03gfyx0
C: arthrobacter sp. rhf34
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: norovirus hu/gii/miyagi/geo132-2/2011/jp
F: gomphina melanaegis (aka macridiscus melanaegis)
G: norovirus hu/gii/miyagi/geo130-3/2011/jp
H: arthrobacter sp. rhf50
I: gateway binary vector r4pgwb401
J: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
K: None of the above. | K |
<Instruct>: Given the context 'Albino C57BL/6J mice homozygous for a tyrosinase mutation (Tyrc-2J) have higher IOPs than their pigmented counterparts.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: influenza b virus (b/india/d0811473/2008)
B: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
C: bacterium enrichment culture clone alo1_glfrudd03gfxt0
D: gomphina melanaegis (aka macridiscus melanaegis)
E: gateway binary vector r4pgwb401
F: trebouxia corticola
G: bacterium enrichment culture clone alo1_glfrudd03gfyx0
H: norovirus hu/gii/miyagi/geo130-3/2011/jp
I: uncultured organism meddcm-oct-s08-c1656
J: paenibacillus sp. pksw2
K: None of the above. | K |
<Instruct>: Given the context 'Conclusions
Genetically distinct mouse strains housed in the same environment have a broad range of IOPs.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: gomphina melanaegis (aka macridiscus melanaegis)
B: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
C: gateway binary vector r4pgwb401
D: influenza b virus (b/india/d0811473/2008)
E: norovirus hu/gii/miyagi/geo131-1/2011/jp
F: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
G: gateway binary vector r4pgwb404
H: bacterium enrichment culture clone alo1_glfrudd03gfxt0
I: uncultured organism meddcm-oct-s08-c1656
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Age, time of day, obesity and diabetes have effects on mouse IOP similar to those in humans and other species.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03g65nh
B: norovirus hu/gii/miyagi/geo132-2/2011/jp
C: gateway binary vector r4pgwb401
D: gomphina melanaegis (aka macridiscus melanaegis)
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: gateway binary vector r4pgwb404
G: bacterium enrichment culture clone alo1_glfrudd03gfxmd
H: bacterium enrichment culture clone alo1_glfrudd03gfxt0
I: norovirus hu/gii/miyagi/geo131-1/2011/jp
J: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
K: None of the above. | K |
<Instruct>: Given the context 'Age, time of day, obesity and diabetes have effects on mouse IOP similar to those in humans and other species.', select the correct biomedical concept corresponding to 'species'. Answer using one of the provided options. | <Options>: A: coleoptera sp. bold:aao4624
B: coleoptera sp. bold:aao4649
C: coleoptera sp. bold:aao4647
D: coleoptera sp. bold:aao4642
E: coleoptera sp. bold:aao4671
F: viola sp. 'ash vale blue'
G: viola suavis
H: coleoptera sp. bold:aao4638
I: coleoptera sp. bold:aao4637
J: lepidoptera sp. bold:aae2373
K: None of the above. | K |
<Instruct>: Given the context 'Age, time of day, obesity and diabetes have effects on mouse IOP similar to those in humans and other species.', select the correct biomedical concept corresponding to 'humans'. Answer using one of the provided options. | <Options>: A: nocardiopsis sp. yim 92628
B: atheriniformes sp. bold:aaa6813
C: tapinoma nigerrimum
D: viola sp. 'ash vale blue'
E: nocardiopsis sp. yim 92626
F: leucoagaricus sp. vellinga 2561
G: phlomis cypria var. cypria
H: plebeia frontalis (plebeia frontalis (friese, 1911)) (aka plebeia frontalis)
I: fusarium sp. s33
J: ajuga pygmaea
K: None of the above. | K |
<Instruct>: Given the context 'These studies demonstrate that mice are a practical and powerful experimental system to study the genetics of IOP regulation and disease processes that raise IOP to harmful levels.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: arthrobacter sp. rhf50
B: uncultured organism meddcm-oct-s08-c1656
C: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
D: norovirus hu/gii/miyagi/geo130-3/2011/jp
E: bacterium enrichment culture clone alo1_glfrudd03gfxmd
F: influenza b virus (b/india/d0811473/2008)
G: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
H: gateway binary vector r4pgwb401
I: paenibacillus sp. pksw2
J: gomphina melanaegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'Identifying such loci allows screening for individuals with an increased risk of developing glaucoma', select the correct biomedical concept corresponding to 'individuals'. Answer using one of the provided options. | <Options>: A: sphingomonas astaxanthinifaciens
B: fusarium sp. s33
C: xylophanes cyrene
D: coleoptera sp. bold:aao4638
E: ajuga nipponensis
F: hypogymnia antarctica (parmelia antarctica) (aka hypogymnia antarctica)
G: coleoptera sp. bold:aao4649
H: xylophanes germen
I: coleoptera sp. bold:aao4621
J: schefflera pubigera (schefflera bengalensis) (aka schefflera pubigera)
K: None of the above. | K |
<Instruct>: Given the context 'Identifying genes contributing to elevated IOP and glaucoma is only the first step, however, and animal models will provide systems for subsequent hypothesis testing and experimental dissection of pathogenesis.
', select the correct biomedical concept corresponding to 'animal'. Answer using one of the provided options. | <Options>: A: passiflora ciliata (passiflora foetida var. ciliata (aiton) mast.) (aka passiflora ciliata)
B: hypogymnia antarctica (parmelia antarctica) (aka hypogymnia antarctica)
C: bacterium btn 14g-3
D: coleoptera sp. bold:aao4638
E: viola suavis
F: parmelia austerodes (aka hypogymnia austerodes)
G: ahnfeltiales
H: bathysiphon sp. isolate 3987
I: coleoptera sp. bold:aao4639
J: viola sp. 'ash vale blue'
K: None of the above. | K |
<Instruct>: Given the context 'Due to conservation in mammalian physiology and the powerful tools of mouse genetics, mice are a very important experimental system for probing the functions (both in health and disease) of many genes recently identified by sequencing the human genome [12].', select the correct biomedical concept corresponding to 'mammalian'. Answer using one of the provided options. | <Options>: A: mytilina ventralis var. brevispina (aka mytilina ventralis brevispina)
B: viola sp. 'ash vale blue'
C: ajuga nipponensis
D: miliolidae sp. isolate 3955
E: xylophanes germen
F: lepidoptera sp. bold:aae2373
G: lepidoptera sp. bold:aae2368
H: globobulimina turgida
I: ahnfeltiales
J: euploea tulliolus
K: None of the above. | K |
<Instruct>: Given the context 'Due to conservation in mammalian physiology and the powerful tools of mouse genetics, mice are a very important experimental system for probing the functions (both in health and disease) of many genes recently identified by sequencing the human genome [12].', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo130-3/2011/jp
B: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
C: gateway binary vector r4pgwb401
D: paenibacillus sp. pksw2
E: arthrobacter sp. rhf50
F: arthrobacter sp. rhf34
G: bacterium enrichment culture clone alo1_glfrudd03gfxt0
H: uncultured organism meddcm-oct-s08-c1656
I: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
J: influenza b virus (b/india/d0811473/2008)
K: None of the above. | K |
<Instruct>: Given the context 'Due to conservation in mammalian physiology and the powerful tools of mouse genetics, mice are a very important experimental system for probing the functions (both in health and disease) of many genes recently identified by sequencing the human genome [12].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: uncultured organism meddcm-oct-s08-c1656
B: arthrobacter sp. rhf50
C: arthrobacter sp. rhf34
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
F: gateway binary vector r4pgwb401
G: influenza b virus (b/india/d0811473/2008)
H: trebouxia corticola
I: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
J: gomphina melanaegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'Due to conservation in mammalian physiology and the powerful tools of mouse genetics, mice are a very important experimental system for probing the functions (both in health and disease) of many genes recently identified by sequencing the human genome [12].', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: ajuga nipponensis
B: coleoptera sp. bold:aao4628
C: fusarium sp. s33
D: leucoagaricus sp. vellinga 2457
E: ajuga pygmaea
F: sphingomonas astaxanthinifaciens
G: phlomis cypria
H: nocardiopsis sp. yim 92628
I: rhodococcus sp. hj-dn6
J: atheriniformes sp. bold:aaa6813
K: None of the above. | K |
<Instruct>: Given the context 'We have focused on developing the mouse system for IOP and glaucoma studies [13-19].', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfyx0
B: norovirus hu/gii/miyagi/geo130-3/2011/jp
C: gateway binary vector r4pgwb404
D: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
E: gomphina melanaegis (aka macridiscus melanaegis)
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: arthrobacter sp. rhf34
H: gateway binary vector r4pgwb401
I: paenibacillus sp. pksw2
J: trebouxia corticola
K: None of the above. | K |
<Instruct>: Given the context 'Mice are expected to be extremely helpful in characterizing genes and mechanisms that affect IOP or the susceptibility of the optic nerve and retina to glaucomatous damage [20].
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gomphina melanegis (aka macridiscus melanaegis)
B: arthrobacter sp. rhf50
C: bacterium enrichment culture clone alo1_glfrudd03g65nh
D: arthrobacter sp. rhf34
E: gateway binary vector r4pgwb404
F: trebouxia corticola
G: bacterium enrichment culture clone alo1_glfrudd03gfxt0
H: norovirus hu/gii/miyagi/geo131-1/2011/jp
I: gateway binary vector r4pgwb401
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Very little is known about the magnitude of IOP of various mouse strains or IOP fluctuation in mice with time or other factors.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
B: bacterium enrichment culture clone alo1_glfrudd03gfyx0
C: bacterium enrichment culture clone alo1_glfrudd03g65nh
D: norovirus hu/gii/miyagi/geo131-1/2011/jp
E: norovirus hu/gii/miyagi/geo132-2/2011/jp
F: paenibacillus sp. pksw2
G: arthrobacter sp. rhf50
H: gateway binary vector r4pgwb404
I: influenza b virus (b/india/d0811473/2008)
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Very little is known about the magnitude of IOP of various mouse strains or IOP fluctuation in mice with time or other factors.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb401
B: gateway binary vector r4pgwb404
C: uncultured organism meddcm-oct-s08-c1656
D: bacterium enrichment culture clone alo1_glfrudd03gfxt0
E: gomphina melanaegis (aka macridiscus melanaegis)
F: norovirus hu/gii/miyagi/geo130-3/2011/jp
G: arthrobacter sp. rhf34
H: norovirus hu/gii/miyagi/geo131-1/2011/jp
I: plethodon shermani stejneger, 1906 (aka plethodon shermani)
J: trebouxia corticola
K: None of the above. | K |
<Instruct>: Given the context 'Previously, we developed a method to measure IOP in mice and reported initial findings on the magnitude of mouse IOP [13].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03g65nh
B: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
C: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
D: uncultured organism meddcm-oct-s08-c1656
E: bacterium enrichment culture clone alo1_glfrudd03gfxmd
F: trebouxia corticola
G: arthrobacter sp. rhf34
H: norovirus hu/gii/miyagi/geo130-3/2011/jp
I: arthrobacter sp. rhf50
J: influenza b virus (b/india/d0811473/2008)
K: None of the above. | K |
<Instruct>: Given the context 'Previously, we developed a method to measure IOP in mice and reported initial findings on the magnitude of mouse IOP [13].', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: paenibacillus sp. pksw2
B: trebouxia corticola
C: norovirus hu/gii/miyagi/geo131-1/2011/jp
D: arthrobacter sp. rhf50
E: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
F: gateway binary vector r4pgwb404
G: influenza b virus (b/india/d0811473/2008)
H: bacterium enrichment culture clone alo1_glfrudd03gfyx0
I: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
J: bacterium enrichment culture clone alo1_glfrudd03gfxmd
K: None of the above. | K |
<Instruct>: Given the context 'The initial experiments demonstrated that in our hands careful ocular cannulation has a very minor effect on IOP (average of -0.3 mmHg, mode -0.5 mmHg) and demonstrated significant differences in intraocular pressure levels between four mouse strains.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
B: gomphina melanegis (aka macridiscus melanaegis)
C: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
D: norovirus hu/gii/miyagi/geo130-3/2011/jp
E: bacterium enrichment culture clone alo1_glfrudd03gfyx0
F: influenza b virus (b/india/d0811473/2008)
G: arthrobacter sp. rhf50
H: gateway binary vector r4pgwb404
I: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
J: bacterium enrichment culture clone alo1_glfrudd03gfxt0
K: None of the above. | K |
<Instruct>: Given the context 'Results
A broad range of IOPs between strains
Figure 1 shows the average IOP of a number of inbred mouse strains that were housed in the same environmental conditions.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
B: arthrobacter sp. rhf34
C: gateway binary vector r4pgwb401
D: paenibacillus sp. pksw2
E: arthrobacter sp. rhf50
F: norovirus hu/gii/miyagi/geo130-3/2011/jp
G: norovirus hu/gii/miyagi/geo132-2/2011/jp
H: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
I: bacterium enrichment culture clone alo1_glfrudd03gfxmd
J: gomphina melanaegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'Figure 1
An almost two-fold range of IOP between genetically distinct mouse strains.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
B: gateway binary vector r4pgwb401
C: arthrobacter sp. rhf50
D: trebouxia corticola
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: gomphina melanegis (aka macridiscus melanaegis)
G: influenza b virus (b/india/d0811473/2008)
H: bacterium enrichment culture clone alo1_glfrudd03gfxt0
I: bacterium enrichment culture clone alo1_glfrudd03gfxmd
J: norovirus hu/gii/miyagi/geo131-1/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Twelve to 25 mice were analyzed for each strain (typically 18 to 20), except for RIIIS/J (7 mice).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb404
B: arthrobacter sp. rhf34
C: paenibacillus sp. pksw2
D: bacterium enrichment culture clone alo1_glfrudd03gfxmd
E: bacterium enrichment culture clone alo1_glfrudd03g65nh
F: trebouxia corticola
G: norovirus hu/gii/miyagi/geo130-3/2011/jp
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: bacterium enrichment culture clone alo1_glfrudd03gfxt0
J: bacterium enrichment culture clone alo1_glfrudd03gfyx0
K: None of the above. | K |
<Instruct>: Given the context 'Twelve to 25 mice were analyzed for each strain (typically 18 to 20), except for RIIIS/J (7 mice).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: arthrobacter sp. rhf50
B: norovirus hu/gii/miyagi/geo131-1/2011/jp
C: paenibacillus sp. pksw2
D: bacterium enrichment culture clone alo1_glfrudd03gfyx0
E: influenza b virus (b/india/d0811473/2008)
F: gomphina melanegis (aka macridiscus melanaegis)
G: bacterium enrichment culture clone alo1_glfrudd03gfxt0
H: uncultured organism meddcm-oct-s08-c1656
I: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
J: gateway binary vector r4pgwb401
K: None of the above. | K |
<Instruct>: Given the context 'Mice of most strains were 6 to 12 months old, except for SEC/1ReJ and SB/Le that were 2 to 3 months old.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb404
B: norovirus hu/gii/miyagi/geo130-3/2011/jp
C: arthrobacter sp. rhf34
D: bacterium enrichment culture clone alo1_glfrudd03g65nh
E: uncultured organism meddcm-oct-s08-c1656
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: bacterium enrichment culture clone alo1_glfrudd03gfxmd
H: influenza b virus (b/india/d0811473/2008)
I: trebouxia corticola
J: paenibacillus sp. pksw2
K: None of the above. | K |
<Instruct>: Given the context 'Approximately half of the CE/J and one third of the BUB/BnJ mice were 16 months old and were pooled with the younger mice, as the IOPs of both ages were the same.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gateway binary vector r4pgwb404
B: bacterium enrichment culture clone alo1_glfrudd03g65nh
C: paenibacillus sp. pksw2
D: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: gomphina melanaegis (aka macridiscus melanaegis)
G: gateway binary vector r4pgwb401
H: arthrobacter sp. rhf50
I: norovirus hu/gii/miyagi/geo131-1/2011/jp
J: trebouxia corticola
K: None of the above. | K |
<Instruct>: Given the context 'Approximately half of the CE/J and one third of the BUB/BnJ mice were 16 months old and were pooled with the younger mice, as the IOPs of both ages were the same.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo130-3/2011/jp
B: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
C: bacterium enrichment culture clone alo1_glfrudd03gfxt0
D: gateway binary vector r4pgwb401
E: norovirus hu/gii/miyagi/geo131-1/2011/jp
F: trebouxia corticola
G: gateway binary vector r4pgwb404
H: arthrobacter sp. rhf34
I: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
J: gomphina melanaegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'For example, the iridocorneal angle and aqueous humor drainage structures are open to the anterior chamber and have normal morphology in both BALB/cJ and CBA/CaJ mice (Figure 2).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: arthrobacter sp. rhf50
B: norovirus hu/gii/miyagi/geo131-1/2011/jp
C: paenibacillus sp. pksw2
D: gateway binary vector r4pgwb404
E: norovirus hu/gii/miyagi/geo130-3/2011/jp
F: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
G: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
H: influenza b virus (b/india/d0811473/2008)
I: gomphina melanaegis (aka macridiscus melanaegis)
J: trebouxia corticola
K: None of the above. | K |
<Instruct>: Given the context 'More than 20% of CBA/CaJ mice had IOPs of over 21 mmHg, which increases risk for glaucoma in humans.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: gomphina melanaegis (aka macridiscus melanaegis)
B: arthrobacter sp. rhf34
C: norovirus hu/gii/miyagi/geo131-1/2011/jp
D: trebouxia corticola
E: plethodon shermani (plethodon shermani stejneger, 1906) (aka plethodon shermani)
F: bacterium enrichment culture clone alo1_glfrudd03gfxt0
G: bacterium enrichment culture clone alo1_glfrudd03gfxmd
H: norovirus hu/gii/miyagi/geo130-3/2011/jp
I: influenza b virus (b/india/d0811473/2008)
J: gateway binary vector r4pgwb401
K: None of the above. | K |
<Instruct>: Given the context 'More than 20% of CBA/CaJ mice had IOPs of over 21 mmHg, which increases risk for glaucoma in humans.', select the correct biomedical concept corresponding to 'humans'. Answer using one of the provided options. | <Options>: A: nocardiopsis sp. yim 92626
B: nocardiopsis sp. yim 92628
C: phlomis cypria
D: salmonella enterica subsp. enterica serovar anatum str. atcc baa-1592 (salmonella enterica subsp. enterica serovar anatum strain atcc baa-1592) (aka salmonella enterica subsp. enterica serovar anatum str. atcc baa-1592)
E: viola sp. 'ash vale blue'
F: atheriniformes sp. bold:aac9977
G: leucoagaricus sp. vellinga 2457
H: fusarium sp. s33
I: atheriniformes sp. bold:aac9978
J: ajuga nipponensis
K: None of the above. | K |
<Instruct>: Given the context 'We aged a small group of these mice (n = 4) to 2 years and histologically analyzed their optic nerves and retinas but they did not develop glaucoma.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: paenibacillus sp. pksw2
B: influenza b virus (b/india/d0811473/2008)
C: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
D: bacterium enrichment culture clone alo1_glfrudd03gfxmd
E: arthrobacter sp. rhf34
F: plethodon shermani stejneger, 1906 (aka plethodon shermani)
G: arthrobacter sp. rhf50
H: gomphina melanaegis (aka macridiscus melanaegis)
I: bacterium enrichment culture clone alo1_glfrudd03gfyx0
J: norovirus hu/gii/miyagi/geo130-3/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'Pigment filled macrophages that resemble human clump cells were often located in the angle of CBA/CaJ mice but were never sufficient to block drainage.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: fusarium sp. s33
B: leucoagaricus sp. vellinga 2457
C: viola sp. 'ash vale blue'
D: rhodococcus sp. hj-dn6
E: ajuga nipponensis
F: nocardiopsis sp. yim 92626
G: plebeia frontalis (plebeia frontalis (friese, 1911)) (aka plebeia frontalis)
H: atheriniformes sp. bold:aac9977
I: coleoptera sp. bold:aao4621
J: mesochorus nhm670937
K: None of the above. | K |
<Instruct>: Given the context 'Pigment filled macrophages that resemble human clump cells were often located in the angle of CBA/CaJ mice but were never sufficient to block drainage.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfxmd
B: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
C: trebouxia corticola
D: uncultured organism meddcm-oct-s08-c1656
E: arthrobacter sp. rhf50
F: gateway binary vector r4pgwb404
G: arthrobacter sp. rhf34
H: gateway binary vector r4pgwb401
I: influenza b virus (b/india/d0811473/2008)
J: gomphina melanegis (aka macridiscus melanaegis)
K: None of the above. | K |
<Instruct>: Given the context 'For incidence, the numerator indicates the number of mice or eyes affected and the denominator indicates the total number analyzed.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: norovirus hu/gii/miyagi/geo130-3/2011/jp
B: gateway binary vector r4pgwb404
C: paenibacillus sp. pksw2
D: influenza b virus (b/india/d0811473/2008)
E: bacterium enrichment culture clone alo1_glfrudd03gfxmd
F: uncultured organism meddcm-oct-s08-c1656
G: norovirus hu/gii/miyagi/geo131-1/2011/jp
H: arthrobacter sp. rhf50
I: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
J: bacterium enrichment culture clone alo1_glfrudd03gfxt0
K: None of the above. | K |
<Instruct>: Given the context 'The mice were 6 to 12 months old at the time of analysis and were not studied at other ages unless indicated.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: plethodon shermani stejneger, 1906 (aka plethodon shermani)
B: bacterium enrichment culture clone alo1_glfrudd03gfxmd
C: paenibacillus sp. pksw2
D: norovirus hu/gii/miyagi/geo131-1/2011/jp
E: uncultured organism meddcm-oct-s08-c1656
F: gomphina melanegis (aka macridiscus melanaegis)
G: arthrobacter sp. rhf50
H: norovirus hu/gii/miyagi/geo130-3/2011/jp
I: bacterium enrichment culture clone alo1_glfrudd03gfxt0
J: trebouxia corticola
K: None of the above. | K |
<Instruct>: Given the context 'Average IOP for age matched mice of the same strain assessed at different times typically differed by no more than 1.5 mmHg, and the differences were usually smaller.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: trebouxia corticola
B: influenza b virus (b/india/d0811473/2008)
C: gateway binary vector r4pgwb401
D: plethodon shermani stejneger, 1906 (aka plethodon shermani)
E: bacterium enrichment culture clone alo1_glfrudd03gfyx0
F: norovirus hu/gii/miyagi/geo130-3/2011/jp
G: paenibacillus sp. pksw2
H: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
I: arthrobacter sp. rhf50
J: bacterium enrichment culture clone alo1_glfrudd03gfxmd
K: None of the above. | K |
<Instruct>: Given the context 'The sex [Male (M) or Female (F)], age (months), and number of mice (n) analyzed for the CBA strains are listed starting with the earliest measurement and ending with the latest: CBA/CaJ, F, n = 22, age 6–7; M, n = 11, age 2; CBA/CaHN, F, n = 16, age 3; M, n = 8, age 3.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
B: influenza a virus (a/mallard/wisconsin/13os2800/2013(h11n9))
C: bacterium enrichment culture clone alo1_glfrudd03gfxt0
D: norovirus hu/gii/miyagi/geo130-3/2011/jp
E: trebouxia corticola
F: bacterium enrichment culture clone alo1_glfrudd03gfyx0
G: arthrobacter sp. rhf50
H: influenza b virus (b/india/d0811473/2008)
I: plethodon shermani stejneger, 1906 (aka plethodon shermani)
J: norovirus hu/gii/miyagi/geo131-1/2011/jp
K: None of the above. | K |
<Instruct>: Given the context 'The number of mice analyzed at each time follows: BALB/cJ 8, 10, 11, 15, 18 and 14, C57BL/6J 10, 14, 21,40,40 and 42.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: bacterium enrichment culture clone alo1_glfrudd03gfxmd
B: bacterium enrichment culture clone alo1_glfrudd03g65nh
C: sheeppox virus ins-1 (sheeppox virus <strain ins-1>) (aka sheeppox virus ins-1)
D: gateway binary vector r4pgwb404
E: uncultured organism meddcm-oct-s08-c1656
F: arthrobacter sp. rhf50
G: arthrobacter sp. rhf34
H: norovirus hu/gii/miyagi/geo131-1/2011/jp
I: trebouxia corticola
J: gomphina melanegis (aka macridiscus melanaegis)
K: None of the above. | K |
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