query
stringlengths 53
129
| positive
listlengths 1
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| negative
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| system
stringlengths 70
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|---|---|---|---|
What is the biomedical concept corresponding to 'lysophospholipid-specific lysophospholipase'?
|
[
"lysophospholipase 1 (homo sapiens)"
] |
[
"lysophospholipase 2 (homo sapiens)",
"lysophospholipase like 1 (homo sapiens)",
"lysophospholipase-like 1 (xenopus tropicalis)",
"patatin like domain 7, lysophospholipase (homo sapiens)",
"lysophospholipase 2 (xenopus tropicalis)",
"lysophospholipase 1 (xenopus tropicalis)",
"patatin like domain 6, lysophospholipase (homo sapiens)",
"lysophospholipase 2 l homeolog (xenopus laevis)",
"lysophospholipase like 1 (danio rerio)"
] |
Given the context 'Herein we report the cDNA cloning of a human brain 25 kDa lysophospholipid-specific lysophospholipase (hLysoPLA).', answer the user's query.
|
What is the biomedical concept corresponding to 'hlysopla'?
|
[
"lysophospholipase 1 (homo sapiens)"
] |
[
"plosl (homo sapiens)",
"lysopld (homo sapiens)",
"spgyla (homo sapiens)",
"lpsa (homo sapiens)",
"spo (homo sapiens) (lactoperoxidase (homo sapiens))",
"hpo (homo sapiens)",
"ospl (homo sapiens)",
"potocki-lupski syndrome (homo sapiens)",
"splash (homo sapiens)"
] |
Given the context 'Herein we report the cDNA cloning of a human brain 25 kDa lysophospholipid-specific lysophospholipase (hLysoPLA).', answer the user's query.
|
What is the biomedical concept corresponding to 'hlysopla'?
|
[
"lysophospholipase 1 (homo sapiens)"
] |
[
"plosl (homo sapiens)",
"lysopld (homo sapiens)",
"spgyla (homo sapiens)",
"lpsa (homo sapiens)",
"spo (homo sapiens) (lactoperoxidase (homo sapiens))",
"hpo (homo sapiens)",
"ospl (homo sapiens)",
"potocki-lupski syndrome (homo sapiens)",
"splash (homo sapiens)"
] |
Given the context 'The hLysoPLA hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms, and exhibits apparent cooperativity and surface dilution kinetics, but not interfacial activation.', answer the user's query.
|
What is the biomedical concept corresponding to 'hlysopla'?
|
[
"lysophospholipase 1 (homo sapiens)"
] |
[
"plosl (homo sapiens)",
"lysopld (homo sapiens)",
"spgyla (homo sapiens)",
"lpsa (homo sapiens)",
"spo (homo sapiens) (lactoperoxidase (homo sapiens))",
"hpo (homo sapiens)",
"ospl (homo sapiens)",
"potocki-lupski syndrome (homo sapiens)",
"splash (homo sapiens)"
] |
Given the context 'Detailed kinetic analysis indicates that the hLysoPLA binds first to the micellar surface and then to the substrate presented on the surface.', answer the user's query.
|
What is the biomedical concept corresponding to 'hlysopla'?
|
[
"lysophospholipase 1 (homo sapiens)"
] |
[
"plosl (homo sapiens)",
"lysopld (homo sapiens)",
"spgyla (homo sapiens)",
"lpsa (homo sapiens)",
"spo (homo sapiens) (lactoperoxidase (homo sapiens))",
"hpo (homo sapiens)",
"ospl (homo sapiens)",
"potocki-lupski syndrome (homo sapiens)",
"splash (homo sapiens)"
] |
Given the context 'The kinetic parameters associated with this surface dilution kinetic model are reported, and it is concluded that hLysoPLA has a single substrate binding site and a surface recognition site.', answer the user's query.
|
What is the biomedical concept corresponding to 'hlysopla'?
|
[
"lysophospholipase 1 (homo sapiens)"
] |
[
"plosl (homo sapiens)",
"lysopld (homo sapiens)",
"spgyla (homo sapiens)",
"lpsa (homo sapiens)",
"spo (homo sapiens) (lactoperoxidase (homo sapiens))",
"hpo (homo sapiens)",
"ospl (homo sapiens)",
"potocki-lupski syndrome (homo sapiens)",
"splash (homo sapiens)"
] |
Given the context 'In contrast to many non-specific lipolytic enzymes that exhibit lysophospholipase activity, hLysoPLA hydrolyzes only lysophospholipids and has no other significant enzymatic activity.', answer the user's query.
|
What is the biomedical concept corresponding to 'hlysopla'?
|
[
"lysophospholipase 1 (homo sapiens)"
] |
[
"plosl (homo sapiens)",
"lysopld (homo sapiens)",
"spgyla (homo sapiens)",
"lpsa (homo sapiens)",
"spo (homo sapiens) (lactoperoxidase (homo sapiens))",
"hpo (homo sapiens)",
"ospl (homo sapiens)",
"potocki-lupski syndrome (homo sapiens)",
"splash (homo sapiens)"
] |
Given the context 'Of special interest, hLysoPLA does not act on plasmenylcholine.', answer the user's query.
|
What is the biomedical concept corresponding to 'brm'?
|
[
"brm (homo sapiens)"
] |
[
"brm (mus musculus)",
"brm (drosophila melanogaster)",
"brt (mus musculus)",
"br (mus musculus)",
"brx1, biogenesis of ribosomes (mus musculus)",
"brm1 (mus musculus)",
"brp (mus musculus)",
"mbr (homo sapiens)",
"brms1 like transcriptional repressor (bos taurus)"
] |
Given the context 'Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
', answer the user's query.
|
What is the biomedical concept corresponding to 'ssx1'?
|
[
"ssx family member 1 (homo sapiens)",
"ssx1 (homo sapiens)"
] |
[
"slx1 homolog a, structure-specific endonuclease subunit (xenopus tropicalis)",
"ssg1 (xenopus laevis) (coiled-coil domain containing 80 s homeolog (xenopus laevis))",
"srpx1 (xenopus laevis) (sushi repeat containing protein x-linked s homeolog (xenopus laevis))",
"ssx1 (saccharomyces cerevisiae s288c)",
"ssx3 (homo sapiens)",
"ssxp1 (homo sapiens)",
"ssx5 (homo sapiens)",
"structure-specific endonuclease subunit slx1 homolog (caenorhabditis elegans)"
] |
Given the context 'The t(X;18)(p11.2;q11.2) chromosomal translocation commonly found in synovial sarcomas fuses the SYT gene on chromosome 18 to either of two similar genes, SSX1 or SSX2, on the X chromosome.', answer the user's query.
|
What is the biomedical concept corresponding to 'ssx2'?
|
[
"ssx2 (homo sapiens)",
"ssx family member 2 (homo sapiens)",
"ssx (homo sapiens) (ssx family member 2 (homo sapiens))"
] |
[
"ssx family member 2b (homo sapiens)",
"ssx (homo sapiens) (ssx family member 2b (homo sapiens))",
"ssxp2 (homo sapiens)",
"ssx2b (homo sapiens)",
"protein ssuh2 homolog (xenopus laevis)",
"ssx2 (saccharomyces cerevisiae s288c)",
"sox-2 (xenopus laevis) (sry-box 2 s homeolog (xenopus laevis))"
] |
Given the context 'The t(X;18)(p11.2;q11.2) chromosomal translocation commonly found in synovial sarcomas fuses the SYT gene on chromosome 18 to either of two similar genes, SSX1 or SSX2, on the X chromosome.', answer the user's query.
|
What is the biomedical concept corresponding to 'snf2'?
|
[
"snf2l2 (homo sapiens)"
] |
[
"snf2 (saccharomyces cerevisiae s288c)",
"swi/snf catalytic subunit snf2 (saccharomyces cerevisiae s288c)",
"snf2h (homo sapiens)",
"snf7-2 (homo sapiens)",
"snf2-beta (homo sapiens)",
"snf2l (homo sapiens)",
"swi2 (saccharomyces cerevisiae s288c)",
"smarcf2 (homo sapiens)",
"snf1 (saccharomyces cerevisiae s288c)"
] |
Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', answer the user's query.
|
What is the biomedical concept corresponding to 'brm'?
|
[
"brm (homo sapiens)"
] |
[
"brm (mus musculus)",
"brm (drosophila melanogaster)",
"brt (mus musculus)",
"br (mus musculus)",
"brx1, biogenesis of ribosomes (mus musculus)",
"brm1 (mus musculus)",
"brp (mus musculus)",
"mbr (homo sapiens)",
"brms1 like transcriptional repressor (bos taurus)"
] |
Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', answer the user's query.
|
What is the biomedical concept corresponding to 'delta-isoforms of the multifunctional ca2+/calmodulin-dependent protein kinase'?
|
[
"calcium/calmodulin dependent protein kinase ii delta (homo sapiens)",
"camk2d (homo sapiens)"
] |
[
"protein kinase c, delta (mus musculus)",
"protein kinase c delta (drosophila melanogaster)",
"calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis)",
"calcium/calmodulin-dependent protein kinase ii, delta (mus musculus)",
"calcium/calmodulin dependent protein kinase ii delta (gallus gallus)",
"protein kinase c delta (xenopus tropicalis)",
"protein kinase c delta (homo sapiens)",
"casein kinase 1 delta (homo sapiens)"
] |
Given the context 'Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium.
', answer the user's query.
|
What is the biomedical concept corresponding to 'camkii isoforms delta2, delta3, delta4, delta8, and delta9'?
|
[
"calcium/calmodulin dependent protein kinase ii delta (homo sapiens)",
"camk2d (homo sapiens)"
] |
[
"calcium/calmodulin-dependent protein kinase ii, delta (mus musculus)",
"camkiid (drosophila melanogaster)",
"calcium/calmodulin dependent protein kinase ii delta (gallus gallus)",
"camkii (xenopus tropicalis) (calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis))",
"calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis)",
"camkiinalpha (homo sapiens)",
"cki-delta (homo sapiens)",
"protein kinase c, delta (mus musculus)"
] |
Given the context 'In this study, we investigated the spectrum of CaMKII isoforms delta2, delta3, delta4, delta8, and delta9 in human striated muscle tissue.', answer the user's query.
|
What is the biomedical concept corresponding to 'glyceraldehyde-3-phosphate dehydrogenase'?
|
[
"glyceraldehyde-3-phosphate dehydrogenase (homo sapiens)",
"gapdh (homo sapiens) (glyceraldehyde-3-phosphate dehydrogenase (homo sapiens))"
] |
[
"glyceraldehyde-3-phosphate dehydrogenase (xenopus tropicalis)",
"glyceraldehyde-3-phosphate dehydrogenase pseudogene (homo sapiens)",
"glyceraldehyde-3-phosphate dehydrogenase (sus scrofa)",
"glyceraldehyde 3-phosphate dehydrogenase (glycine max)",
"glyceraldehyde-3-phosphate dehydrogenase (gallus gallus)",
"glyceraldehyde 3 phosphate dehydrogenase 1 (drosophila melanogaster)",
"phosphoglycerate dehydrogenase (homo sapiens)",
"glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (homo sapiens)"
] |
Given the context 'relative to the expression of glyceraldehyde-3-phosphate dehydrogenase in diseased hearts (101. 6+/-11.0% versus 64.9+/-9.9% in the nonfailing group; P < 0.05, n=6).', answer the user's query.
|
What is the biomedical concept corresponding to 'delta-camkii'?
|
[
"calcium/calmodulin dependent protein kinase ii delta (homo sapiens)",
"camk2d (homo sapiens)"
] |
[
"camkiid (drosophila melanogaster)",
"camkii (xenopus tropicalis) (calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis))",
"calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis)",
"calcium/calmodulin-dependent protein kinase ii, delta (mus musculus)",
"[d]-camkii (mus musculus)",
"camkii (drosophila melanogaster)",
"camk2 (xenopus tropicalis) (calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis))",
"calcium/calmodulin dependent protein kinase ii delta (gallus gallus)"
] |
Given the context 'At the protein level, by using a subclass-specific antibody, we observed a similar increase of a delta-CaMKII-specific signal (7.2+/-1.0 versus 3.8+/-0.7 optical density units in the nonfailing group; P < 0.05, n=4 through 6).', answer the user's query.
|
What is the biomedical concept corresponding to 'delta-camkii'?
|
[
"calcium/calmodulin dependent protein kinase ii delta (homo sapiens)",
"camk2d (homo sapiens)"
] |
[
"camkiid (drosophila melanogaster)",
"camkii (xenopus tropicalis) (calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis))",
"calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis)",
"calcium/calmodulin-dependent protein kinase ii, delta (mus musculus)",
"[d]-camkii (mus musculus)",
"camkii (drosophila melanogaster)",
"camk2 (xenopus tropicalis) (calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis))",
"calcium/calmodulin dependent protein kinase ii delta (gallus gallus)"
] |
Given the context 'Our data characterize for the first time the delta-CaMKII isoform expression pattern in human hearts and demonstrate changes in this expression pattern in heart failure.', answer the user's query.
|
What is the biomedical concept corresponding to 'insulin receptor related receptor'?
|
[
"insulin receptor related receptor (homo sapiens)"
] |
[
"insr (homo sapiens)",
"insulin receptor (homo sapiens)",
"insulin receptor-related receptor (mus musculus)",
"insulin receptor-related receptor (rattus norvegicus)",
"igfr (homo sapiens)",
"igf2r (homo sapiens)",
"insulin receptor related receptor (sus scrofa)",
"insulin receptor related receptor (xenopus tropicalis)",
"igfir (homo sapiens)"
] |
Given the context 'Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.
', answer the user's query.
|
What is the biomedical concept corresponding to 'insulin receptor related receptor'?
|
[
"insulin receptor related receptor (homo sapiens)"
] |
[
"insr (homo sapiens)",
"insulin receptor (homo sapiens)",
"insulin receptor-related receptor (mus musculus)",
"insulin receptor-related receptor (rattus norvegicus)",
"igfr (homo sapiens)",
"igf2r (homo sapiens)",
"insulin receptor related receptor (sus scrofa)",
"insulin receptor related receptor (xenopus tropicalis)",
"igfir (homo sapiens)"
] |
Given the context 'The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor with intrinsic tyrosine kinase activity.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor with intrinsic tyrosine kinase activity.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'The IRR shares large homology with the insulin and the insulin-like growth factor-1 (IGF-I) receptor with regard to amino acid sequence and protein structure.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'So far, only a partial human sequence containing the complete 3' end has been reported, although the full-length human IRR cDNA had been used for transfection studies and functional analysis of the receptor.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'We have isolated a full-length human IRR cDNA and report on the 5' translated and untranslated region of the human IRR gene.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'We have isolated a full-length human IRR cDNA and report on the 5' translated and untranslated region of the human IRR gene.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'The full length IRR sequence contains 4150 bases and shares a high degree of homology with the guinea pig IRR cDNA sequence and rat IRR sequences that had been reported earlier on by others.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'Sequencing of the IRR cDNA revealed that the human IRR cDNA contains 341 bases corresponding to the IRR 5' end in addition to the bases that had been reported on before.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'Sequencing of the IRR cDNA revealed that the human IRR cDNA contains 341 bases corresponding to the IRR 5' end in addition to the bases that had been reported on before.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'Sequencing of the IRR cDNA revealed that the human IRR cDNA contains 341 bases corresponding to the IRR 5' end in addition to the bases that had been reported on before.', answer the user's query.
|
What is the biomedical concept corresponding to 'irr'?
|
[
"irr (homo sapiens)",
"insulin receptor related receptor (homo sapiens)",
"insrr (homo sapiens)"
] |
[
"insr (homo sapiens)",
"ifngr1 (homo sapiens)",
"ifngr (homo sapiens)",
"il1r3 (homo sapiens)",
"ifnr (homo sapiens)",
"il1r (homo sapiens)",
"ip10-r (homo sapiens)"
] |
Given the context 'The full length cDNA for the human IRR can now be used for functional expression studies and to elucidate the nature of the ligand for this receptor type.', answer the user's query.
|
What is the biomedical concept corresponding to 'npt1'?
|
[
"npt1 (homo sapiens)",
"npt-1 (homo sapiens)"
] |
[
"solute carrier family 1 member 1 (homo sapiens)",
"npat (homo sapiens)",
"npt2 (homo sapiens)",
"slc1 (homo sapiens)",
"slc-1 (homo sapiens)",
"nrt1 (homo sapiens)",
"solute carrier family 1 member 2 (homo sapiens)",
"solute carrier family 11 member 1 (homo sapiens)"
] |
Given the context 'The deduced amino acids sequence shows an overall homology of 48% with the human renal NPT1 protein.', answer the user's query.
|
What is the biomedical concept corresponding to 'tgf-beta 1'?
|
[
"transforming growth factor beta 1 (homo sapiens)",
"tgf-beta1 (homo sapiens)",
"tgfb1 (homo sapiens)",
"tgfbeta (homo sapiens)",
"tgfb (homo sapiens)"
] |
[
"transforming growth factor beta receptor 1 (homo sapiens)",
"transforming growth factor beta 1 (bos taurus)",
"interferon beta 1 (homo sapiens)",
"transforming growth factor beta 1 (xenopus tropicalis)",
"il1-beta (homo sapiens)"
] |
Given the context 'Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6.
', answer the user's query.
|
What is the biomedical concept corresponding to 'c-c chemokine receptor 6'?
|
[
"c-c motif chemokine receptor 6 (homo sapiens)",
"cc-ckr-6 (homo sapiens)",
"c-c ckr-6 (homo sapiens)",
"cmkbr6 (homo sapiens)",
"ccr-6 (homo sapiens)"
] |
[
"c-x-c motif chemokine receptor 6 (homo sapiens)",
"c-c motif chemokine receptor 7 (homo sapiens)",
"cc-ckr-8 (homo sapiens)",
"c-c motif chemokine receptor 8 (homo sapiens)",
"cxcr6 (homo sapiens)"
] |
Given the context 'Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6.
', answer the user's query.
|
What is the biomedical concept corresponding to 'ccr6'?
|
[
"ccr-6 (homo sapiens)",
"cc-ckr-6 (homo sapiens)",
"ccr6 (homo sapiens)",
"c-c ckr-6 (homo sapiens)",
"cmkbr6 (homo sapiens)",
"c-c motif chemokine receptor 6 (homo sapiens)"
] |
[
"cc-ckr-8 (homo sapiens)",
"c-x-c motif chemokine receptor 6 (homo sapiens)",
"ccr-8 (homo sapiens)",
"cxcr6 (homo sapiens)"
] |
Given the context 'Although CD34+ progenitor-derived immature dendritic cells (DCs) express CCR6, several recent studies reported that monocyte-derived immature DCs do not do so.', answer the user's query.
|
What is the biomedical concept corresponding to 'gm-csf'?
|
[
"colony stimulating factor 2 (homo sapiens)",
"gmcsf (homo sapiens)",
"csf2 (homo sapiens)",
"csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))"
] |
[
"colony stimulating factor 1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)",
"csf-1 (homo sapiens)",
"multi-csf (homo sapiens)",
"csf1 (homo sapiens)",
"gm-csf (mus musculus)"
] |
Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', answer the user's query.
|
What is the biomedical concept corresponding to 'il-4'?
|
[
"interleukin 4 (homo sapiens)",
"il-4 (homo sapiens)",
"il4 (homo sapiens)"
] |
[
"il-4 (bos taurus)",
"interleukin 4 (bos taurus)",
"il4 (bos taurus)",
"bolf1 (human gammaherpesvirus 4)",
"bdlf4 (human gammaherpesvirus 4)",
"bllf1 (human gammaherpesvirus 4)",
"interleukin 5 (homo sapiens)"
] |
Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', answer the user's query.
|
What is the biomedical concept corresponding to 'tgf-beta 1'?
|
[
"transforming growth factor beta 1 (homo sapiens)",
"tgf-beta1 (homo sapiens)",
"tgfb1 (homo sapiens)",
"tgfbeta (homo sapiens)",
"tgfb (homo sapiens)"
] |
[
"transforming growth factor beta receptor 1 (homo sapiens)",
"transforming growth factor beta 1 (bos taurus)",
"interferon beta 1 (homo sapiens)",
"transforming growth factor beta 1 (xenopus tropicalis)",
"il1-beta (homo sapiens)"
] |
Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', answer the user's query.
|
What is the biomedical concept corresponding to 'larc'?
|
[
"larc (homo sapiens)"
] |
[
"larc (xenopus tropicalis)",
"larc (mus musculus)",
"lnccrla (homo sapiens)",
"lncsrlr (homo sapiens)",
"lar (homo sapiens)",
"lncarsr (homo sapiens)",
"lard (homo sapiens)",
"lnc-rhl (homo sapiens)",
"lar1 (homo sapiens)"
] |
Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', answer the user's query.
|
What is the biomedical concept corresponding to 'macrophage inflammatory protein-3 alpha'?
|
[
"mip-3-alpha (homo sapiens)",
"mip-3a (homo sapiens)",
"mip3a (homo sapiens)"
] |
[
"mip-3 (homo sapiens)",
"c-c motif chemokine ligand 3 (homo sapiens)",
"c-x-c motif chemokine ligand 3 (homo sapiens)",
"ccl3 (homo sapiens)",
"mcp-3 (homo sapiens)",
"mip3 (homo sapiens)",
"mip-1-alpha (homo sapiens)"
] |
Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', answer the user's query.
|
What is the biomedical concept corresponding to 'larc'?
|
[
"larc (homo sapiens)"
] |
[
"larc (xenopus tropicalis)",
"larc (mus musculus)",
"lnccrla (homo sapiens)",
"lncsrlr (homo sapiens)",
"lar (homo sapiens)",
"lncarsr (homo sapiens)",
"lard (homo sapiens)",
"lnc-rhl (homo sapiens)",
"lar1 (homo sapiens)"
] |
Given the context 'These immature DCs expressed one class of high-affinity binding sites for LARC, and expressed both CCR6 mRNA and protein.', answer the user's query.
|
What is the biomedical concept corresponding to 'ccr6'?
|
[
"ccr-6 (homo sapiens)",
"cc-ckr-6 (homo sapiens)",
"ccr6 (homo sapiens)",
"c-c ckr-6 (homo sapiens)",
"cmkbr6 (homo sapiens)",
"c-c motif chemokine receptor 6 (homo sapiens)"
] |
[
"cc-ckr-8 (homo sapiens)",
"c-x-c motif chemokine receptor 6 (homo sapiens)",
"ccr-8 (homo sapiens)",
"cxcr6 (homo sapiens)"
] |
Given the context 'These immature DCs expressed one class of high-affinity binding sites for LARC, and expressed both CCR6 mRNA and protein.', answer the user's query.
|
What is the biomedical concept corresponding to 'larc'?
|
[
"larc (homo sapiens)"
] |
[
"larc (xenopus tropicalis)",
"larc (mus musculus)",
"lnccrla (homo sapiens)",
"lncsrlr (homo sapiens)",
"lar (homo sapiens)",
"lncarsr (homo sapiens)",
"lard (homo sapiens)",
"lnc-rhl (homo sapiens)",
"lar1 (homo sapiens)"
] |
Given the context 'Therefore, LARC-CCR6 interaction presumably also contributes to the regulation of trafficking of monocyte-derived DCs, and utilization of TGF-beta can potentially provide a ready source of CCR6+ monocyte-derived DCs for therapeutic purposes.', answer the user's query.
|
What is the biomedical concept corresponding to 'ccr6'?
|
[
"ccr-6 (homo sapiens)",
"cc-ckr-6 (homo sapiens)",
"ccr6 (homo sapiens)",
"c-c ckr-6 (homo sapiens)",
"cmkbr6 (homo sapiens)",
"c-c motif chemokine receptor 6 (homo sapiens)"
] |
[
"cc-ckr-8 (homo sapiens)",
"c-x-c motif chemokine receptor 6 (homo sapiens)",
"ccr-8 (homo sapiens)",
"cxcr6 (homo sapiens)"
] |
Given the context 'Therefore, LARC-CCR6 interaction presumably also contributes to the regulation of trafficking of monocyte-derived DCs, and utilization of TGF-beta can potentially provide a ready source of CCR6+ monocyte-derived DCs for therapeutic purposes.', answer the user's query.
|
What is the biomedical concept corresponding to 'ccr6'?
|
[
"ccr-6 (homo sapiens)",
"cc-ckr-6 (homo sapiens)",
"ccr6 (homo sapiens)",
"c-c ckr-6 (homo sapiens)",
"cmkbr6 (homo sapiens)",
"c-c motif chemokine receptor 6 (homo sapiens)"
] |
[
"cc-ckr-8 (homo sapiens)",
"c-x-c motif chemokine receptor 6 (homo sapiens)",
"ccr-8 (homo sapiens)",
"cxcr6 (homo sapiens)"
] |
Given the context 'Therefore, LARC-CCR6 interaction presumably also contributes to the regulation of trafficking of monocyte-derived DCs, and utilization of TGF-beta can potentially provide a ready source of CCR6+ monocyte-derived DCs for therapeutic purposes.', answer the user's query.
|
What is the biomedical concept corresponding to 'pknalpha'?
|
[
"pkn-alpha (homo sapiens)",
"pkn (homo sapiens)",
"pkn1 (homo sapiens)"
] |
[
"pku-alpha (homo sapiens)",
"pkn-alpha (xenopus laevis)",
"pkn-alpha (xenopus tropicalis)",
"pkn2 (homo sapiens)",
"pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster))",
"prkn (homo sapiens)",
"prkr (homo sapiens)"
] |
Given the context 'Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
', answer the user's query.
|
What is the biomedical concept corresponding to 'pknalpha'?
|
[
"pkn-alpha (homo sapiens)",
"pkn (homo sapiens)",
"pkn1 (homo sapiens)"
] |
[
"pku-alpha (homo sapiens)",
"pkn-alpha (xenopus laevis)",
"pkn-alpha (xenopus tropicalis)",
"pkn2 (homo sapiens)",
"pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster))",
"prkn (homo sapiens)",
"prkr (homo sapiens)"
] |
Given the context 'PKNbeta had high sequence homology with PKNalpha, originally isolated PKN, especially in the repeats of charged amino acid-rich region with leucine-zipper like sequences (CZ region/HR1), in the carboxyl-terminal catalytic domain, and in approximately 130 amino acid stretch (D region/HR2), located between CZ region/HR1 and the catalytic domain.', answer the user's query.
|
What is the biomedical concept corresponding to 'pknalpha'?
|
[
"pkn-alpha (homo sapiens)",
"pkn (homo sapiens)",
"pkn1 (homo sapiens)"
] |
[
"pku-alpha (homo sapiens)",
"pkn-alpha (xenopus laevis)",
"pkn-alpha (xenopus tropicalis)",
"pkn2 (homo sapiens)",
"pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster))",
"prkn (homo sapiens)",
"prkr (homo sapiens)"
] |
Given the context 'However, the amino acid sequence of PKNbeta differed from that of PKNalpha in the region immediately amino-terminal to the catalytic domain, which contained two distinct proline-rich sequences consistent with the class II consensus sequence, PXXPXR, for binding to SH3 domain.', answer the user's query.
|
What is the biomedical concept corresponding to 'pknalpha'?
|
[
"pkn-alpha (homo sapiens)",
"pkn (homo sapiens)",
"pkn1 (homo sapiens)"
] |
[
"pku-alpha (homo sapiens)",
"pkn-alpha (xenopus laevis)",
"pkn-alpha (xenopus tropicalis)",
"pkn2 (homo sapiens)",
"pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster))",
"prkn (homo sapiens)",
"prkr (homo sapiens)"
] |
Given the context 'Distribution of PKNbeta differed from that of PKNalpha in the following two respects: (1) Northern blotting indicated that PKNbeta mRNA could not be detected in human adult tissues, but was expressed abundantly in human cancer cell lines; (2) immunochemical analysis indicated that PKNbeta localized in nucleus and perinuclear Golgi apparatus, and was almost absent in cytoplasmic region in NIH3T3 cells.', answer the user's query.
|
What is the biomedical concept corresponding to 'pknalpha'?
|
[
"pkn-alpha (homo sapiens)",
"pkn (homo sapiens)",
"pkn1 (homo sapiens)"
] |
[
"pku-alpha (homo sapiens)",
"pkn-alpha (xenopus laevis)",
"pkn-alpha (xenopus tropicalis)",
"pkn2 (homo sapiens)",
"pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster))",
"prkn (homo sapiens)",
"prkr (homo sapiens)"
] |
Given the context 'Recombinant PKNbeta expressed in COS7 cells displayed autophosphorylation and peptide kinase activity, but was found to be significantly less responsive to arachidonic acid than PKNalpha.', answer the user's query.
|
What is the biomedical concept corresponding to 'ndp'?
|
[
"ndp (homo sapiens)",
"norrin cystine knot growth factor ndp (homo sapiens)"
] |
[
"ndn (homo sapiens)",
"ndnf (homo sapiens)",
"ndpp (homo sapiens)",
"ndp (rattus norvegicus)",
"ndc1 transmembrane nucleoporin (homo sapiens)",
"ndp (xenopus tropicalis)",
"naked cuticle homolog 1 (xenopus tropicalis)",
"ndpkd (homo sapiens)"
] |
Given the context 'Coats' disease of the retina (unilateral retinal telangiectasis) caused by somatic mutation in the NDP gene: a role for norrin in retinal angiogenesis.
', answer the user's query.
|
What is the biomedical concept corresponding to 'norrin'?
|
[
"norrin cystine knot growth factor ndp (homo sapiens)"
] |
[
"norrin cystine knot growth factor ndp (rattus norvegicus)",
"norp (rattus norvegicus)",
"norbin (rattus norvegicus)",
"neuritin 1-like (rattus norvegicus)",
"connectin (rattus norvegicus)",
"nrn (rattus norvegicus)",
"nynrin (rattus norvegicus)",
"nor-2 (rattus norvegicus)",
"ninein-like (rattus norvegicus)"
] |
Given the context 'Coats' disease of the retina (unilateral retinal telangiectasis) caused by somatic mutation in the NDP gene: a role for norrin in retinal angiogenesis.
', answer the user's query.
|
What is the biomedical concept corresponding to 'ndp'?
|
[
"ndp (homo sapiens)",
"norrin cystine knot growth factor ndp (homo sapiens)"
] |
[
"ndn (homo sapiens)",
"ndnf (homo sapiens)",
"ndpp (homo sapiens)",
"ndp (rattus norvegicus)",
"ndc1 transmembrane nucleoporin (homo sapiens)",
"ndp (xenopus tropicalis)",
"naked cuticle homolog 1 (xenopus tropicalis)",
"ndpkd (homo sapiens)"
] |
Given the context 'Both carried a missense mutation within the NDP gene on chromosome Xp11.2.', answer the user's query.
|
What is the biomedical concept corresponding to 'ndp'?
|
[
"ndp (homo sapiens)",
"norrin cystine knot growth factor ndp (homo sapiens)"
] |
[
"ndn (homo sapiens)",
"ndnf (homo sapiens)",
"ndpp (homo sapiens)",
"ndp (rattus norvegicus)",
"ndc1 transmembrane nucleoporin (homo sapiens)",
"ndp (xenopus tropicalis)",
"naked cuticle homolog 1 (xenopus tropicalis)",
"ndpkd (homo sapiens)"
] |
Given the context 'Subsequently analysis of the retinas of nine enucleated eyes from males with Coats' disease demonstrated in one a somatic mutation in the NDP gene which was not present within non-retinal tissue.', answer the user's query.
|
What is the biomedical concept corresponding to 'ndp'?
|
[
"ndp (homo sapiens)",
"norrin cystine knot growth factor ndp (homo sapiens)"
] |
[
"ndn (homo sapiens)",
"ndnf (homo sapiens)",
"ndpp (homo sapiens)",
"ndp (rattus norvegicus)",
"ndc1 transmembrane nucleoporin (homo sapiens)",
"ndp (xenopus tropicalis)",
"naked cuticle homolog 1 (xenopus tropicalis)",
"ndpkd (homo sapiens)"
] |
Given the context 'We suggest that Coats' telangiectasis is secondary to somatic mutation in the NDP gene which results in a deficiency of norrin (the protein product of the NDP gene) within the developing retina.', answer the user's query.
|
What is the biomedical concept corresponding to 'norrin'?
|
[
"norrin cystine knot growth factor ndp (homo sapiens)"
] |
[
"norrin cystine knot growth factor ndp (rattus norvegicus)",
"norp (rattus norvegicus)",
"norbin (rattus norvegicus)",
"neuritin 1-like (rattus norvegicus)",
"connectin (rattus norvegicus)",
"nrn (rattus norvegicus)",
"nynrin (rattus norvegicus)",
"nor-2 (rattus norvegicus)",
"ninein-like (rattus norvegicus)"
] |
Given the context 'We suggest that Coats' telangiectasis is secondary to somatic mutation in the NDP gene which results in a deficiency of norrin (the protein product of the NDP gene) within the developing retina.', answer the user's query.
|
What is the biomedical concept corresponding to 'ndp'?
|
[
"ndp (homo sapiens)",
"norrin cystine knot growth factor ndp (homo sapiens)"
] |
[
"ndn (homo sapiens)",
"ndnf (homo sapiens)",
"ndpp (homo sapiens)",
"ndp (rattus norvegicus)",
"ndc1 transmembrane nucleoporin (homo sapiens)",
"ndp (xenopus tropicalis)",
"naked cuticle homolog 1 (xenopus tropicalis)",
"ndpkd (homo sapiens)"
] |
Given the context 'We suggest that Coats' telangiectasis is secondary to somatic mutation in the NDP gene which results in a deficiency of norrin (the protein product of the NDP gene) within the developing retina.', answer the user's query.
|
What is the biomedical concept corresponding to 'luteinizing hormone beta-subunit'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))"
] |
[
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"lutropin subunit beta (bos taurus)",
"follicle stimulating hormone subunit beta (homo sapiens)",
"thyroid stimulating hormone subunit beta (homo sapiens)",
"chorionic gonadotropin subunit beta 1 (homo sapiens)",
"tsh-beta (homo sapiens)",
"lhb (homo sapiens) (chorionic gonadotropin subunit beta 3 (homo sapiens))"
] |
Given the context 'A common polymorphic allele of the human luteinizing hormone beta-subunit gene: additional mutations and differential function of the promoter sequence.
', answer the user's query.
|
What is the biomedical concept corresponding to 'luteinizing hormone (lh) beta-subunit'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"luteinizing hormone subunit beta (sus scrofa)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (bos taurus)",
"lhb (homo sapiens) (chorionic gonadotropin subunit beta 3 (homo sapiens))",
"follicle stimulating hormone subunit beta (homo sapiens)",
"thyroid stimulating hormone subunit beta (homo sapiens)",
"chorionic gonadotropin subunit beta 1 (homo sapiens)"
] |
Given the context 'A common genetic variant (V) of the human luteinizing hormone (LH) beta-subunit gene was recently discovered.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'The V-LH molecules have higher bioactivity in vitro, but shorter half-life in circulation, which apparently is related to the alterations of LH function observed in individuals homo- and heterozygous for the V-LHbeta allele.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'We have now studied whether additional mutations in the V-LHbeta promoter sequence could contribute to the altered physiology of the LH variant molecules.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'The 661 bp 5'-flanking region of the V-LHbeta gene, retrieved from human genomic DNA by PCR, contained eight single-nucleotide changes, as compared with the wild-type (wt) LHbeta promoter.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'The 661 bp 5'-flanking region of the V-LHbeta gene, retrieved from human genomic DNA by PCR, contained eight single-nucleotide changes, as compared with the wild-type (wt) LHbeta promoter.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'Reporter constructs with various lengths of the wt- and V-LH promoter sequences, driving the firefly luciferase reporter gene, were transfected into an immortalized mouse pituitary cell line, LbetaT(2), known to express the endogenous LHbeta gene, and into a non-endocrine human embryonic kidney cell line, HEK 293.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'Basal expression levels of the V-LHbeta promoter constructs were on average 36% higher in LbetaT(2)cells ( P < 0.001; n = 29), and 40% higher in HEK 293 cells ( P < 0.001; n = 16), as compared with the respective wt sequences.', answer the user's query.
|
What is the biomedical concept corresponding to 'gonado- tropin-releasing hormone'?
|
[
"lhrh (homo sapiens)",
"gnrh (homo sapiens)",
"gonadotropin releasing hormone 1 (homo sapiens)"
] |
[
"growth hormone releasing hormone (homo sapiens)",
"growth hormone releasing hormone (xenopus tropicalis)",
"lhrh (xenopus tropicalis)",
"growth hormone releasing hormone (rattus norvegicus)",
"gonadotropin releasing hormone 1 (xenopus tropicalis)",
"gnrh (xenopus tropicalis)",
"hypocretin (orexin) neuropeptide precursor (xenopus tropicalis)"
] |
Given the context 'Numerous qualitative and quantitative differences were found between the two cell lines in responses of the two promoter sequences to stimulation with 12- O -tetradecanoylphorbol-13-acetate, forskolin, 8-bromo-cAMP, progesterone and gonado- tropin-releasing hormone.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'In conclusion, the V-LHbeta promoter has higher basal activity, and differs in response to hormonal stimulation, as compared with the wt-LHbeta promoter.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'In conclusion, the V-LHbeta promoter has higher basal activity, and differs in response to hormonal stimulation, as compared with the wt-LHbeta promoter.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'The altered promoter function of the V-LHbeta gene provides evidence for differences in regulation of the wt- and V-LHbeta genes, which may contribute to the differences observed in pituitary-gonadal function between carriers of the two LHbeta alleles.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'The altered promoter function of the V-LHbeta gene provides evidence for differences in regulation of the wt- and V-LHbeta genes, which may contribute to the differences observed in pituitary-gonadal function between carriers of the two LHbeta alleles.', answer the user's query.
|
What is the biomedical concept corresponding to 'lhbeta'?
|
[
"luteinizing hormone subunit beta (homo sapiens)",
"lhb (homo sapiens) (luteinizing hormone subunit beta (homo sapiens))",
"lsh-beta (homo sapiens)"
] |
[
"lutropin subunit beta-like (xenopus laevis)",
"lutropin subunit beta-like (xenopus tropicalis)",
"lutropin subunit beta (bos taurus)",
"luteinizing hormone subunit beta (sus scrofa)",
"luteinizing hormone subunit beta (oryctolagus cuniculus)",
"luteinizing hormone subunit beta (bos taurus)",
"luteinizing hormone subunit beta (xenopus tropicalis)"
] |
Given the context 'The altered promoter function of the V-LHbeta gene provides evidence for differences in regulation of the wt- and V-LHbeta genes, which may contribute to the differences observed in pituitary-gonadal function between carriers of the two LHbeta alleles.', answer the user's query.
|
What is the biomedical concept corresponding to 'hydroxypyruvate reductase'?
|
[
"glyoxylate and hydroxypyruvate reductase (homo sapiens)"
] |
[
"hydroxypyruvate reductase (arabidopsis thaliana)",
"glyoxylate and hydroxypyruvate reductase (bos taurus)",
"glyoxylate and hydroxypyruvate reductase (rattus norvegicus)",
"glyoxylate reductase (escherichia coli str. k-12 substr. mg1655)",
"glyoxylate reductase 1 homolog (xenopus tropicalis)",
"glyoxylate/hydroxypyruvate reductase a (escherichia coli str. k-12 substr. mg1655)",
"hdhpr (homo sapiens)",
"hydroxypyruvate reductase 3 (arabidopsis thaliana)",
"grhpr (xenopus tropicalis) (glyoxylate reductase/hydroxypyruvate reductase, gene 1 (xenopus tropicalis))"
] |
Given the context 'The gene encoding hydroxypyruvate reductase (GRHPR) is mutated in patients with primary hyperoxaluria type II.
', answer the user's query.
|
What is the biomedical concept corresponding to 'grhpr'?
|
[
"grhpr (homo sapiens)"
] |
[
"growth hormone releasing hormone receptor (homo sapiens)",
"ghrhr (homo sapiens)",
"ghrfr (homo sapiens)",
"prolactin releasing hormone receptor (homo sapiens)",
"gonadotropin releasing hormone receptor (homo sapiens)",
"grhr (homo sapiens)",
"grpr (homo sapiens)",
"grr1 (glycine max)",
"gr (homo sapiens)"
] |
Given the context 'The gene encoding hydroxypyruvate reductase (GRHPR) is mutated in patients with primary hyperoxaluria type II.
', answer the user's query.
|
What is the biomedical concept corresponding to 'glyoxylate reductase'?
|
[
"glyoxylate and hydroxypyruvate reductase (homo sapiens)"
] |
[
"glyoxylate reductase 1 homolog (xenopus tropicalis)",
"glyoxylate reductase 1 homolog (homo sapiens)",
"glyoxylate reductase (escherichia coli str. k-12 substr. mg1655)",
"glyoxylate reductase 1 (arabidopsis thaliana)",
"glyoxylate reductase 1 homolog (rattus norvegicus)",
"glyoxylate reductase 1 homolog (bos taurus)",
"glyoxylate reductase 1 homolog (sus scrofa)",
"reductase (glycine max)",
"glyoxylate/succinic semialdehyde reductase 1 (glycine max)"
] |
Given the context 'We identified a glyoxylate reductase/hydroxypyruvate reductase (GRHPR) cDNA clone from a human liver expressed sequence tag (EST) library.', answer the user's query.
|
What is the biomedical concept corresponding to 'hydroxypyruvate reductase'?
|
[
"glyoxylate and hydroxypyruvate reductase (homo sapiens)"
] |
[
"hydroxypyruvate reductase (arabidopsis thaliana)",
"glyoxylate and hydroxypyruvate reductase (bos taurus)",
"glyoxylate and hydroxypyruvate reductase (rattus norvegicus)",
"glyoxylate reductase (escherichia coli str. k-12 substr. mg1655)",
"glyoxylate reductase 1 homolog (xenopus tropicalis)",
"glyoxylate/hydroxypyruvate reductase a (escherichia coli str. k-12 substr. mg1655)",
"hdhpr (homo sapiens)",
"hydroxypyruvate reductase 3 (arabidopsis thaliana)",
"grhpr (xenopus tropicalis) (glyoxylate reductase/hydroxypyruvate reductase, gene 1 (xenopus tropicalis))"
] |
Given the context 'We identified a glyoxylate reductase/hydroxypyruvate reductase (GRHPR) cDNA clone from a human liver expressed sequence tag (EST) library.', answer the user's query.
|
What is the biomedical concept corresponding to 'grhpr'?
|
[
"grhpr (homo sapiens)"
] |
[
"growth hormone releasing hormone receptor (homo sapiens)",
"ghrhr (homo sapiens)",
"ghrfr (homo sapiens)",
"prolactin releasing hormone receptor (homo sapiens)",
"gonadotropin releasing hormone receptor (homo sapiens)",
"grhr (homo sapiens)",
"grpr (homo sapiens)",
"grr1 (glycine max)",
"gr (homo sapiens)"
] |
Given the context 'We identified a glyoxylate reductase/hydroxypyruvate reductase (GRHPR) cDNA clone from a human liver expressed sequence tag (EST) library.', answer the user's query.
|
What is the biomedical concept corresponding to 'glyoxylate reductase'?
|
[
"glyoxylate and hydroxypyruvate reductase (homo sapiens)"
] |
[
"glyoxylate reductase 1 homolog (xenopus tropicalis)",
"glyoxylate reductase 1 homolog (homo sapiens)",
"glyoxylate reductase (escherichia coli str. k-12 substr. mg1655)",
"glyoxylate reductase 1 (arabidopsis thaliana)",
"glyoxylate reductase 1 homolog (rattus norvegicus)",
"glyoxylate reductase 1 homolog (bos taurus)",
"glyoxylate reductase 1 homolog (sus scrofa)",
"reductase (glycine max)",
"glyoxylate/succinic semialdehyde reductase 1 (glycine max)"
] |
Given the context 'Transient transfection of the cDNA clone into COS cells verified that it encoded an enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities.', answer the user's query.
|
What is the biomedical concept corresponding to 'grhpr'?
|
[
"grhpr (homo sapiens)"
] |
[
"growth hormone releasing hormone receptor (homo sapiens)",
"ghrhr (homo sapiens)",
"ghrfr (homo sapiens)",
"prolactin releasing hormone receptor (homo sapiens)",
"gonadotropin releasing hormone receptor (homo sapiens)",
"grhr (homo sapiens)",
"grpr (homo sapiens)",
"grr1 (glycine max)",
"gr (homo sapiens)"
] |
Given the context 'The genomic structure of the human GRHPR gene was determined and contains nine exons and eight introns and spans approximately 9 kb pericentromeric on chromosome 9.', answer the user's query.
|
What is the biomedical concept corresponding to 'grhpr'?
|
[
"grhpr (homo sapiens)"
] |
[
"growth hormone releasing hormone receptor (homo sapiens)",
"ghrhr (homo sapiens)",
"ghrfr (homo sapiens)",
"prolactin releasing hormone receptor (homo sapiens)",
"gonadotropin releasing hormone receptor (homo sapiens)",
"grhr (homo sapiens)",
"grpr (homo sapiens)",
"grr1 (glycine max)",
"gr (homo sapiens)"
] |
Given the context 'Four PH2 patients representing two pairs of siblings from two unrelated families were analyzed for mutations in GRHPR by single strand conformation polymorphism analysis.', answer the user's query.
|
What is the biomedical concept corresponding to 'grhpr'?
|
[
"grhpr (homo sapiens)"
] |
[
"growth hormone releasing hormone receptor (homo sapiens)",
"ghrhr (homo sapiens)",
"ghrfr (homo sapiens)",
"prolactin releasing hormone receptor (homo sapiens)",
"gonadotropin releasing hormone receptor (homo sapiens)",
"grhr (homo sapiens)",
"grpr (homo sapiens)",
"grr1 (glycine max)",
"gr (homo sapiens)"
] |
Given the context 'The cDNA that we have identified represents the first characterization of an animal GRHPR sequence.', answer the user's query.
|
What is the biomedical concept corresponding to 'ectodysplasin'?
|
[
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))",
"hed (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"ectodysplasin a (xenopus tropicalis)",
"ectodysplasin a (sus scrofa)",
"ectodysplasin a (danio rerio)",
"ed3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"ectodysplasin a receptor (xenopus tropicalis)",
"ectodysplasin a (bos taurus)"
] |
Given the context 'Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and co-localizes with cytoskeletal structures at lateral and apical surfaces of cells.
', answer the user's query.
|
What is the biomedical concept corresponding to 'eda'?
|
[
"eda (homo sapiens)",
"eda1 (homo sapiens)",
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"eda3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"edd (arabidopsis thaliana)",
"eda1 (arabidopsis thaliana)",
"eda1 (xenopus laevis) (ectodysplasin a s homeolog (xenopus laevis))",
"eda1r (homo sapiens)"
] |
Given the context 'Anhidrotic ectodermal dysplasia (EDA) is a human genetic disorder of impaired ectodermal appendage development.', answer the user's query.
|
What is the biomedical concept corresponding to 'eda'?
|
[
"eda (homo sapiens)",
"eda1 (homo sapiens)",
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"eda3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"edd (arabidopsis thaliana)",
"eda1 (arabidopsis thaliana)",
"eda1 (xenopus laevis) (ectodysplasin a s homeolog (xenopus laevis))",
"eda1r (homo sapiens)"
] |
Given the context 'The EDA gene encodes isoforms of a novel transmembrane protein, ectodysplasin.', answer the user's query.
|
What is the biomedical concept corresponding to 'ectodysplasin'?
|
[
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))",
"hed (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"ectodysplasin a (xenopus tropicalis)",
"ectodysplasin a (sus scrofa)",
"ectodysplasin a (danio rerio)",
"ed3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"ectodysplasin a receptor (xenopus tropicalis)",
"ectodysplasin a (bos taurus)"
] |
Given the context 'The EDA gene encodes isoforms of a novel transmembrane protein, ectodysplasin.', answer the user's query.
|
What is the biomedical concept corresponding to 'ectodysplasin'?
|
[
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))",
"hed (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"ectodysplasin a (xenopus tropicalis)",
"ectodysplasin a (sus scrofa)",
"ectodysplasin a (danio rerio)",
"ed3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"ectodysplasin a receptor (xenopus tropicalis)",
"ectodysplasin a (bos taurus)"
] |
Given the context 'In order to understand better the function of the ectodysplasin protein molecule and its domains, we have studied the processing and localization of wild-type and mutated isoforms in transfected human fetal kidney 293 and monkey kidney COS-1 cells.', answer the user's query.
|
What is the biomedical concept corresponding to 'ectodysplasin'?
|
[
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))",
"hed (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"ectodysplasin a (xenopus tropicalis)",
"ectodysplasin a (sus scrofa)",
"ectodysplasin a (danio rerio)",
"ed3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"ectodysplasin a receptor (xenopus tropicalis)",
"ectodysplasin a (bos taurus)"
] |
Given the context 'Similar to other members of collagenous membrane proteins and members of TNF-related ligands, ectodysplasin is a type II membrane protein and it forms trimers.', answer the user's query.
|
What is the biomedical concept corresponding to 'ectodysplasin'?
|
[
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))",
"hed (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"ectodysplasin a (xenopus tropicalis)",
"ectodysplasin a (sus scrofa)",
"ectodysplasin a (danio rerio)",
"ed3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"ectodysplasin a receptor (xenopus tropicalis)",
"ectodysplasin a (bos taurus)"
] |
Given the context 'The membrane localization of ectodysplasin is asymmetrical: it is found on the apical and lateral surfaces of the cells where it co-localizes with cytoskeletal structures.', answer the user's query.
|
What is the biomedical concept corresponding to 'ectodysplasin'?
|
[
"ectodysplasin a (homo sapiens)",
"ectd1 (homo sapiens) (ectodysplasin a (homo sapiens))",
"hed (homo sapiens) (ectodysplasin a (homo sapiens))"
] |
[
"ectodysplasin a receptor (homo sapiens)",
"ectodysplasin a (xenopus tropicalis)",
"ectodysplasin a (sus scrofa)",
"ectodysplasin a (danio rerio)",
"ed3 (homo sapiens) (ectodysplasin a receptor (homo sapiens))",
"ectodysplasin a receptor (xenopus tropicalis)",
"ectodysplasin a (bos taurus)"
] |
Given the context 'Our results suggest that ectodysplasin is a new member in the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcl-2'?
|
[
"bcl-2 (homo sapiens)",
"bcl2 (homo sapiens)",
"bcl2 apoptosis regulator (homo sapiens)"
] |
[
"bcl2-l-2 (homo sapiens)",
"bcl2l2 (homo sapiens)",
"bcl2 like 2 (homo sapiens)",
"bcl-b (homo sapiens)",
"bcl2l (homo sapiens)",
"bcl2 interacting protein 2 (homo sapiens)",
"ccnb2 (homo sapiens)"
] |
Given the context 'Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.
Bcl-2 is the best characterized inhibitor of apoptosis, although the molecular basis of this action is not fully understood.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcl-2'?
|
[
"bcl-2 (homo sapiens)",
"bcl2 (homo sapiens)",
"bcl2 apoptosis regulator (homo sapiens)"
] |
[
"bcl2-l-2 (homo sapiens)",
"bcl2l2 (homo sapiens)",
"bcl2 like 2 (homo sapiens)",
"bcl-b (homo sapiens)",
"bcl2l (homo sapiens)",
"bcl2 interacting protein 2 (homo sapiens)",
"ccnb2 (homo sapiens)"
] |
Given the context 'Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.
Bcl-2 is the best characterized inhibitor of apoptosis, although the molecular basis of this action is not fully understood.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcl-2'?
|
[
"bcl-2 (homo sapiens)",
"bcl2 (homo sapiens)",
"bcl2 apoptosis regulator (homo sapiens)"
] |
[
"bcl2-l-2 (homo sapiens)",
"bcl2l2 (homo sapiens)",
"bcl2 like 2 (homo sapiens)",
"bcl-b (homo sapiens)",
"bcl2l (homo sapiens)",
"bcl2 interacting protein 2 (homo sapiens)",
"ccnb2 (homo sapiens)"
] |
Given the context 'Co-immunoprecipitation analysis confirmed that Bis interacted with Bcl-2 in vivo.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcl-2'?
|
[
"bcl-2 (homo sapiens)",
"bcl2 (homo sapiens)",
"bcl2 apoptosis regulator (homo sapiens)"
] |
[
"bcl2-l-2 (homo sapiens)",
"bcl2l2 (homo sapiens)",
"bcl2 like 2 (homo sapiens)",
"bcl-b (homo sapiens)",
"bcl2l (homo sapiens)",
"bcl2 interacting protein 2 (homo sapiens)",
"ccnb2 (homo sapiens)"
] |
Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', answer the user's query.
|
What is the biomedical concept corresponding to 'bax'?
|
[
"bax (homo sapiens)",
"bcl2 associated x, apoptosis regulator (homo sapiens)"
] |
[
"bak1 (homo sapiens)",
"bak-like (homo sapiens)",
"bcl-x (homo sapiens)",
"bak (homo sapiens)",
"bak-2 (homo sapiens)",
"bcl2 apoptosis regulator (homo sapiens)",
"bax (escherichia coli str. k-12 substr. mg1655)",
"bak2 (homo sapiens)"
] |
Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', answer the user's query.
|
What is the biomedical concept corresponding to 'fas'?
|
[
"fas cell surface death receptor (homo sapiens)",
"fas (homo sapiens) (fas cell surface death receptor (homo sapiens))"
] |
[
"fasas (homo sapiens)",
"fas activated serine/threonine kinase (homo sapiens)",
"fast (homo sapiens) (fas activated serine/threonine kinase (homo sapiens))",
"fasn (homo sapiens)",
"fas-as (homo sapiens)",
"fasps (homo sapiens)",
"fas (homo sapiens) (fatty acid synthase (homo sapiens))",
"fas (gallus gallus)"
] |
Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcl-2'?
|
[
"bcl-2 (homo sapiens)",
"bcl2 (homo sapiens)",
"bcl2 apoptosis regulator (homo sapiens)"
] |
[
"bcl2-l-2 (homo sapiens)",
"bcl2l2 (homo sapiens)",
"bcl2 like 2 (homo sapiens)",
"bcl-b (homo sapiens)",
"bcl2l (homo sapiens)",
"bcl2 interacting protein 2 (homo sapiens)",
"ccnb2 (homo sapiens)"
] |
Given the context 'These results suggest that Bis is a novel modulator of cellular anti-apoptotic activity that functions through its interaction with Bcl-2.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcar1'?
|
[
"bcar1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (homo sapiens)"
] |
[
"bcar1 (bos taurus)",
"bcar1p1 (homo sapiens)",
"bca1 (homo sapiens)",
"bcar1 pseudogene 1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (bos taurus)",
"bca-1 (homo sapiens)",
"bcar2 (homo sapiens)",
"bcar1 (xenopus tropicalis)"
] |
Given the context 'BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.
BACKGROUND: Treatment of breast cancer with the antiestrogen tamoxifen is effective in approximately one half of the patients with estrogen receptor-positive disease, but tumors recur frequently because of the development of metastases that are resistant to tamoxifen.', answer the user's query.
|
What is the biomedical concept corresponding to 'p130cas'?
|
[
"p130cas (homo sapiens)"
] |
[
"p130cas (xenopus tropicalis)",
"p130cas (xenopus laevis) (bcar1, cas family scaffold protein s homeolog (xenopus laevis))",
"p130cas (sus scrofa)",
"p130cas (rattus norvegicus)",
"p130cas (drosophila melanogaster)",
"p130cas (xenopus laevis) (bcar1, cas family scaffold protein l homeolog (xenopus laevis))",
"p120cas (homo sapiens)",
"dcas (drosophila melanogaster) (p130cas (drosophila melanogaster))",
"p120cas (xenopus tropicalis)"
] |
Given the context 'BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.
BACKGROUND: Treatment of breast cancer with the antiestrogen tamoxifen is effective in approximately one half of the patients with estrogen receptor-positive disease, but tumors recur frequently because of the development of metastases that are resistant to tamoxifen.', answer the user's query.
|
What is the biomedical concept corresponding to 'breast cancer antiestrogen resistance 1'?
|
[
"bcar1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (homo sapiens)"
] |
[
"breast cancer associated esr1 regulating natural antisense transcript 1 (homo sapiens)",
"breast cancer anti-estrogen resistance 1 (mus musculus)",
"brcaa1 (homo sapiens)",
"bcar1 (sus scrofa)",
"breast cancer anti-estrogen resistance 4 (homo sapiens)",
"bcar1 (bos taurus)",
"bcar3 antisense rna 1 (homo sapiens)",
"bcan antisense rna 1 (homo sapiens)"
] |
Given the context 'In this study, we isolated and characterized the crucial gene at the breast cancer antiestrogen resistance 1 (BCAR1) locus.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcar1'?
|
[
"bcar1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (homo sapiens)"
] |
[
"bcar1 (bos taurus)",
"bcar1p1 (homo sapiens)",
"bca1 (homo sapiens)",
"bcar1 pseudogene 1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (bos taurus)",
"bca-1 (homo sapiens)",
"bcar2 (homo sapiens)",
"bcar1 (xenopus tropicalis)"
] |
Given the context 'In this study, we isolated and characterized the crucial gene at the breast cancer antiestrogen resistance 1 (BCAR1) locus.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcar1'?
|
[
"bcar1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (homo sapiens)"
] |
[
"bcar1 (bos taurus)",
"bcar1p1 (homo sapiens)",
"bca1 (homo sapiens)",
"bcar1 pseudogene 1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (bos taurus)",
"bca-1 (homo sapiens)",
"bcar2 (homo sapiens)",
"bcar1 (xenopus tropicalis)"
] |
Given the context 'Transfer of the BCAR1 locus from retrovirus-mutated, antiestrogen-resistant cells to estrogen-dependent ZR-75-1 cells by cell fusion conferred an antiestrogen-resistant phenotype on the recipient cells.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcar1'?
|
[
"bcar1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (homo sapiens)"
] |
[
"bcar1 (bos taurus)",
"bcar1p1 (homo sapiens)",
"bca1 (homo sapiens)",
"bcar1 pseudogene 1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (bos taurus)",
"bca-1 (homo sapiens)",
"bcar2 (homo sapiens)",
"bcar1 (xenopus tropicalis)"
] |
Given the context 'The complete coding sequence of BCAR1 was isolated by use of exon-trapping and complementary DNA (cDNA) library screening.', answer the user's query.
|
What is the biomedical concept corresponding to 'bcar1'?
|
[
"bcar1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (homo sapiens)"
] |
[
"bcar1 (bos taurus)",
"bcar1p1 (homo sapiens)",
"bca1 (homo sapiens)",
"bcar1 pseudogene 1 (homo sapiens)",
"bcar1 scaffold protein, cas family member (bos taurus)",
"bca-1 (homo sapiens)",
"bcar2 (homo sapiens)",
"bcar1 (xenopus tropicalis)"
] |
Given the context 'Sequence analysis of human BCAR1 cDNA predicted a protein of 870 amino acids that was strongly homologous to rat p130Cas-adapter protein.', answer the user's query.
|
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