query stringlengths 53 129 | positive listlengths 1 8 | negative listlengths 10 10 | system stringlengths 70 592 |
|---|---|---|---|
What is the biomedical concept corresponding to 'rha'? | [
"rha (homo sapiens)"
] | [
"rhr (homo sapiens)",
"rhd (homo sapiens)",
"rhs (homo sapiens)",
"rhag (homo sapiens)",
"rhce (homo sapiens)",
"rhc (homo sapiens)",
"rhii (homo sapiens)",
"rha (drosophila melanogaster)",
"rh associated glycoprotein (homo sapiens)",
"rh30a (homo sapiens)"
] | Given the context 'The region of BRCA1 which interacts with RHA and, thus, the holoenzyme complex, corresponds to subregions of the BRCT domain of BRCA1 (ref. 9).', answer the user's query. |
What is the biomedical concept corresponding to 'brca1'? | [
"brca1 (homo sapiens)",
"brca1 dna repair associated (homo sapiens)",
"brcai (homo sapiens)",
"brcc1 (homo sapiens) (brca1 dna repair associated (homo sapiens))"
] | [
"breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans)",
"pseudo-brca1 (homo sapiens)",
"brcaa1 (homo sapiens)",
"brca1 associated protein (homo sapiens)",
"brca1p1 (homo sapiens)",
"brca1 pseudogene 1 (homo sapiens)",
"brisc and brca1 a co... | Given the context 'The region of BRCA1 which interacts with RHA and, thus, the holoenzyme complex, corresponds to subregions of the BRCT domain of BRCA1 (ref. 9).', answer the user's query. |
What is the biomedical concept corresponding to 'rha'? | [
"rha (homo sapiens)"
] | [
"rhr (homo sapiens)",
"rhd (homo sapiens)",
"rhs (homo sapiens)",
"rhag (homo sapiens)",
"rhce (homo sapiens)",
"rhc (homo sapiens)",
"rhii (homo sapiens)",
"rha (drosophila melanogaster)",
"rh associated glycoprotein (homo sapiens)",
"rh30a (homo sapiens)"
] | Given the context 'This interaction was shown to occur in yeast nuclei, and expression in human cells of a truncated RHA molecule which retains binding to BRCA1 inhibited transcriptional activation mediated by the BRCA1 carboxy terminus.', answer the user's query. |
What is the biomedical concept corresponding to 'brca1'? | [
"brca1 (homo sapiens)",
"brca1 dna repair associated (homo sapiens)",
"brcai (homo sapiens)",
"brcc1 (homo sapiens) (brca1 dna repair associated (homo sapiens))"
] | [
"breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans)",
"pseudo-brca1 (homo sapiens)",
"brcaa1 (homo sapiens)",
"brca1 associated protein (homo sapiens)",
"brca1p1 (homo sapiens)",
"brca1 pseudogene 1 (homo sapiens)",
"brisc and brca1 a co... | Given the context 'This interaction was shown to occur in yeast nuclei, and expression in human cells of a truncated RHA molecule which retains binding to BRCA1 inhibited transcriptional activation mediated by the BRCA1 carboxy terminus.', answer the user's query. |
What is the biomedical concept corresponding to 'brca1'? | [
"brca1 (homo sapiens)",
"brca1 dna repair associated (homo sapiens)",
"brcai (homo sapiens)",
"brcc1 (homo sapiens) (brca1 dna repair associated (homo sapiens))"
] | [
"breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans)",
"pseudo-brca1 (homo sapiens)",
"brcaa1 (homo sapiens)",
"brca1 associated protein (homo sapiens)",
"brca1p1 (homo sapiens)",
"brca1 pseudogene 1 (homo sapiens)",
"brisc and brca1 a co... | Given the context 'This interaction was shown to occur in yeast nuclei, and expression in human cells of a truncated RHA molecule which retains binding to BRCA1 inhibited transcriptional activation mediated by the BRCA1 carboxy terminus.', answer the user's query. |
What is the biomedical concept corresponding to 'brca1'? | [
"brca1 (homo sapiens)",
"brca1 dna repair associated (homo sapiens)",
"brcai (homo sapiens)",
"brcc1 (homo sapiens) (brca1 dna repair associated (homo sapiens))"
] | [
"breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans)",
"pseudo-brca1 (homo sapiens)",
"brcaa1 (homo sapiens)",
"brca1 associated protein (homo sapiens)",
"brca1p1 (homo sapiens)",
"brca1 pseudogene 1 (homo sapiens)",
"brisc and brca1 a co... | Given the context 'These data are the first to identify a specific protein interaction with the BRCA1 C-terminal domain and are consistent with the model that BRCA1 functions as a transcriptional coactivator.', answer the user's query. |
What is the biomedical concept corresponding to 'brca1'? | [
"brca1 (homo sapiens)",
"brca1 dna repair associated (homo sapiens)",
"brcai (homo sapiens)",
"brcc1 (homo sapiens) (brca1 dna repair associated (homo sapiens))"
] | [
"breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans)",
"pseudo-brca1 (homo sapiens)",
"brcaa1 (homo sapiens)",
"brca1 associated protein (homo sapiens)",
"brca1p1 (homo sapiens)",
"brca1 pseudogene 1 (homo sapiens)",
"brisc and brca1 a co... | Given the context 'These data are the first to identify a specific protein interaction with the BRCA1 C-terminal domain and are consistent with the model that BRCA1 functions as a transcriptional coactivator.', answer the user's query. |
What is the biomedical concept corresponding to 'cnga3'? | [
"cnga3 (homo sapiens)",
"cyclic nucleotide gated channel subunit alpha 3 (homo sapiens)"
] | [
"cnga4 (homo sapiens)",
"cnga3.l (xenopus laevis)",
"cnga2 (homo sapiens)",
"cyclic nucleotide gated channel alpha 3 (mus musculus)",
"cng3 (xenopus laevis) (cyclic nucleotide gated channel alpha 3 l homeolog (xenopus laevis))",
"cnga3 (bos taurus) (cyclic nucleotide gated channel subunit alpha 3 (bos tau... | Given the context 'Recently, a suitable candidate gene, CNGA3, encoding the alpha-subunit of the cone photoreceptor cGMP-gated cation channel, a key component of the phototransduction pathway, has been cloned and assigned to human chromosome 2q11 (refs 3,4).', answer the user's query. |
What is the biomedical concept corresponding to 'cnga3'? | [
"cnga3 (homo sapiens)",
"cyclic nucleotide gated channel subunit alpha 3 (homo sapiens)"
] | [
"cnga4 (homo sapiens)",
"cnga3.l (xenopus laevis)",
"cnga2 (homo sapiens)",
"cyclic nucleotide gated channel alpha 3 (mus musculus)",
"cng3 (xenopus laevis) (cyclic nucleotide gated channel alpha 3 l homeolog (xenopus laevis))",
"cnga3 (bos taurus) (cyclic nucleotide gated channel subunit alpha 3 (bos tau... | Given the context 'We report the identification of missense mutations in CNGA3 in five families with RM.', answer the user's query. |
What is the biomedical concept corresponding to 'csnb2'? | [
"csnb2 (homo sapiens)",
"csnb2a (homo sapiens)",
"csnbx2 (homo sapiens)"
] | [
"csnb2b (homo sapiens)",
"csnb1b (homo sapiens)",
"csnb1 (homo sapiens)",
"csnb1a (homo sapiens)",
"csnb1c (homo sapiens)",
"csnb3 (homo sapiens)",
"csnb1g (homo sapiens)",
"csnb1i (homo sapiens)",
"csnb1d (homo sapiens)",
"csnb1h (homo sapiens)"
] | Given the context 'The locus for the incomplete form of X-linked congenital stationary night blindness (CSNB2) maps to a 1.1-Mb region in Xp11.23 between markers DXS722 and DXS255.', answer the user's query. |
What is the biomedical concept corresponding to 'cacna1f'? | [
"cacna1f (homo sapiens)"
] | [
"cacna1h (homo sapiens)",
"cacna1g (homo sapiens)",
"cacna1f (rattus norvegicus)",
"cacna1a.l (xenopus laevis) (calcium channel, voltage-dependent, p/q type, alpha 1a subunit l homeolog (xenopus laevis))",
"cacna1c (homo sapiens)",
"cacna1f (danio rerio)",
"cacna1a.l (xenopus laevis) (calcium channel, v... | Given the context 'We identified a retina-specific calcium channel alpha1-subunit gene (CACNA1F) in this region, consisting of 48 exons encoding 1966 amino acids and showing high homology to L-type calcium channel alpha1-subunits.', answer the user's query. |
What is the biomedical concept corresponding to 'csnb2'? | [
"csnb2 (homo sapiens)",
"csnb2a (homo sapiens)",
"csnbx2 (homo sapiens)"
] | [
"csnb2b (homo sapiens)",
"csnb1b (homo sapiens)",
"csnb1 (homo sapiens)",
"csnb1a (homo sapiens)",
"csnb1c (homo sapiens)",
"csnb3 (homo sapiens)",
"csnb1g (homo sapiens)",
"csnb1i (homo sapiens)",
"csnb1d (homo sapiens)",
"csnb1h (homo sapiens)"
] | Given the context 'Mutation analysis in 13 families with CSNB2 revealed nine different mutations in 10 families, including three nonsense and one frameshift mutation.', answer the user's query. |
What is the biomedical concept corresponding to 'csnb2'? | [
"csnb2 (homo sapiens)",
"csnb2a (homo sapiens)",
"csnbx2 (homo sapiens)"
] | [
"csnb2b (homo sapiens)",
"csnb1b (homo sapiens)",
"csnb1 (homo sapiens)",
"csnb1a (homo sapiens)",
"csnb1c (homo sapiens)",
"csnb3 (homo sapiens)",
"csnb1g (homo sapiens)",
"csnb1i (homo sapiens)",
"csnb1d (homo sapiens)",
"csnb1h (homo sapiens)"
] | Given the context 'These data indicate that aberrations in a voltage-gated calcium channel, presumably causing a decrease in neurotransmitter release from photoreceptor presynaptic terminals, are a frequent cause of CSNB2.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'ZW10 helps recruit dynactin and dynein to the kinetochore.
', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"l(1)zw10 (drosophila melanogaster)"
] | [
"zw10 (homo sapiens)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"zw12 (drosophila melanogaster)",
"zw9 (drosophila melanogaster)",
"zw8 (drosophila mel... | Given the context 'Mutations in the Drosophila melanogaster zw10 gene, which encodes a conserved, essential kinetochore component, abolish the ability of dynein to localize to kinetochores.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'Several similarities between the behavior of ZW10 protein and dynein further support a role for ZW10 in the recruitment of dynein to the kinetochore: (a) in response to bipolar tension across the chromosomes, both proteins mostly leave the kinetochore at metaphase, when their association with the spindle becomes apparent; (b) ZW10 and dynein both bind to functional neocentromeres of structurally acentric minichromosomes; and (c) the localization of both ZW10 and dynein to the kinetochore is abolished in cells mutant for the gene rough deal.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'Several similarities between the behavior of ZW10 protein and dynein further support a role for ZW10 in the recruitment of dynein to the kinetochore: (a) in response to bipolar tension across the chromosomes, both proteins mostly leave the kinetochore at metaphase, when their association with the spindle becomes apparent; (b) ZW10 and dynein both bind to functional neocentromeres of structurally acentric minichromosomes; and (c) the localization of both ZW10 and dynein to the kinetochore is abolished in cells mutant for the gene rough deal.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'Several similarities between the behavior of ZW10 protein and dynein further support a role for ZW10 in the recruitment of dynein to the kinetochore: (a) in response to bipolar tension across the chromosomes, both proteins mostly leave the kinetochore at metaphase, when their association with the spindle becomes apparent; (b) ZW10 and dynein both bind to functional neocentromeres of structurally acentric minichromosomes; and (c) the localization of both ZW10 and dynein to the kinetochore is abolished in cells mutant for the gene rough deal.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'Several similarities between the behavior of ZW10 protein and dynein further support a role for ZW10 in the recruitment of dynein to the kinetochore: (a) in response to bipolar tension across the chromosomes, both proteins mostly leave the kinetochore at metaphase, when their association with the spindle becomes apparent; (b) ZW10 and dynein both bind to functional neocentromeres of structurally acentric minichromosomes; and (c) the localization of both ZW10 and dynein to the kinetochore is abolished in cells mutant for the gene rough deal.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'ZW10's role in the recruitment of dynein to the kinetochore is likely to be reasonably direct, because dynamitin, the p50 subunit of the dynactin complex, interacts with ZW10 in a yeast two-hybrid screen.', answer the user's query. |
What is the biomedical concept corresponding to 'dynamitin'? | [
"dynamitin (homo sapiens)",
"dynactin subunit 2 (homo sapiens)"
] | [
"dynamitin (drosophila melanogaster)",
"dynamitin (xenopus laevis) (dynactin subunit 2 s homeolog (xenopus laevis))",
"dynamitin (xenopus laevis) (dynactin subunit 2 l homeolog (xenopus laevis))",
"p50/dynamitin (drosophila melanogaster)",
"dynamitin (danio rerio)",
"dynamitin (xenopus tropicalis)",
"dy... | Given the context 'ZW10's role in the recruitment of dynein to the kinetochore is likely to be reasonably direct, because dynamitin, the p50 subunit of the dynactin complex, interacts with ZW10 in a yeast two-hybrid screen.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'ZW10's role in the recruitment of dynein to the kinetochore is likely to be reasonably direct, because dynamitin, the p50 subunit of the dynactin complex, interacts with ZW10 in a yeast two-hybrid screen.', answer the user's query. |
What is the biomedical concept corresponding to 'zw10'? | [
"zw10 (homo sapiens)"
] | [
"zw10 (drosophila melanogaster)",
"zw-10 (drosophila melanogaster)",
"zw11 (drosophila melanogaster)",
"zw10 (xenopus laevis) (zw10 kinetochore protein s homeolog (xenopus laevis))",
"zw10 (xenopus laevis) (zw10 kinetochore protein l homeolog (xenopus laevis))",
"l(1)zw10 (drosophila melanogaster)",
"zw... | Given the context 'Since in zw10 mutants no defects in chromosome behavior are observed before anaphase onset, our results suggest that dynein at the kinetochore is essential for neither microtubule capture nor congression to the metaphase plate.', answer the user's query. |
What is the biomedical concept corresponding to 'ifn-inducible nucleoprotein ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi15 (homo sapiens)",
"ifi6 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi11 (homo sapiens)",
"ifi60 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi30 (homo sapiens)",
"ifi4 (homo sapiens)"
] | Given the context 'The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations.
IFI 16 is an interferon-inducible nucleoprotein expressed by human monocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations.
IFI 16 is an interferon-inducible nucleoprotein expressed by human monocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'IFI 16 and a related mouse protein, p202, control cellular proliferation by binding and modulating the functions of cell cycle regulatory factors including p53 and the retinoblastoma gene product, pRb.', answer the user's query. |
What is the biomedical concept corresponding to 'p53'? | [
"p53 (homo sapiens)",
"tumor protein p53 (homo sapiens)",
"tp53 (homo sapiens)"
] | [
"p53 (xenopus laevis) (tumor protein p53 s homeolog (xenopus laevis))",
"p53 (xenopus laevis) (tumor protein p53 l homeolog (xenopus laevis))",
"p532 (homo sapiens)",
"cellular tumor antigen p53-like (gallus gallus)",
"tumor protein p53 s homeolog (xenopus laevis)",
"p53n (homo sapiens)",
"cellular tumo... | Given the context 'IFI 16 and a related mouse protein, p202, control cellular proliferation by binding and modulating the functions of cell cycle regulatory factors including p53 and the retinoblastoma gene product, pRb.', answer the user's query. |
What is the biomedical concept corresponding to 'retinoblastoma gene product, prb'? | [
"prb (homo sapiens)",
"p105-rb (homo sapiens)"
] | [
"prb1 (xenopus laevis) (retinoblastoma-like 1 s homeolog (xenopus laevis))",
"rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster))",
"rb (drosophila melanogaster) (retinoblastoma-family protein 2 (drosophila melanogaster))",
"prb (drosophila melanogaster)",
"prb2 (homo sapi... | Given the context 'IFI 16 and a related mouse protein, p202, control cellular proliferation by binding and modulating the functions of cell cycle regulatory factors including p53 and the retinoblastoma gene product, pRb.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'In this study, we examined IFI 16 expression in myeloid precursor cells cultured in vitro in colony-forming assays using granulocyte (G-) and granulocyte-macrophage (GM-) colony-stimulating factor (CSF).', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'IFI 16 was expressed in 100% of CD34+ cells isolated from human bone marrow.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 molecule (gallus gallus)",
"cd340 (homo sapiens)",
"cd34 molecule (rattus norvegicus)",
"cd349 (homo sapiens)",
"cd34 antigen (mus musculus)",
"cd34 (gallus gallus)",
"cd34 (mus musculus)",
"cd34 (sus scrofa)",
"cd34 molecule (sus scrofa)"
] | Given the context 'IFI 16 was expressed in 100% of CD34+ cells isolated from human bone marrow.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 molecule (gallus gallus)",
"cd340 (homo sapiens)",
"cd34 molecule (rattus norvegicus)",
"cd349 (homo sapiens)",
"cd34 antigen (mus musculus)",
"cd34 (gallus gallus)",
"cd34 (mus musculus)",
"cd34 (sus scrofa)",
"cd34 molecule (sus scrofa)"
] | Given the context 'When the CD34+ cells were induced to differentiate, two sub-populations of cells were identified by two-color cytofluorography: the CD14+ (monocytoid) cells all expressed IFI 16, whereas the CD14- (polymorphonuclear precursor) cells did not.', answer the user's query. |
What is the biomedical concept corresponding to 'cd14'? | [
"cd14 molecule (homo sapiens)",
"cd14 (homo sapiens) (cd14 molecule (homo sapiens))"
] | [
"cd14 molecule (gallus gallus)",
"cd14 antigen (mus musculus)",
"cd14 (homo sapiens) (nadh:ubiquinone oxidoreductase subunit a2 (homo sapiens))",
"cd14 (mus musculus)",
"cd14 (oryctolagus cuniculus)",
"cd14 molecule (oryctolagus cuniculus)",
"cd142 (homo sapiens)",
"cd14 (gallus gallus)",
"cd141 (ho... | Given the context 'When the CD34+ cells were induced to differentiate, two sub-populations of cells were identified by two-color cytofluorography: the CD14+ (monocytoid) cells all expressed IFI 16, whereas the CD14- (polymorphonuclear precursor) cells did not.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'When the CD34+ cells were induced to differentiate, two sub-populations of cells were identified by two-color cytofluorography: the CD14+ (monocytoid) cells all expressed IFI 16, whereas the CD14- (polymorphonuclear precursor) cells did not.', answer the user's query. |
What is the biomedical concept corresponding to 'cd14'? | [
"cd14 molecule (homo sapiens)",
"cd14 (homo sapiens) (cd14 molecule (homo sapiens))"
] | [
"cd14 molecule (gallus gallus)",
"cd14 antigen (mus musculus)",
"cd14 (homo sapiens) (nadh:ubiquinone oxidoreductase subunit a2 (homo sapiens))",
"cd14 (mus musculus)",
"cd14 (oryctolagus cuniculus)",
"cd14 molecule (oryctolagus cuniculus)",
"cd142 (homo sapiens)",
"cd14 (gallus gallus)",
"cd141 (ho... | Given the context 'When the CD34+ cells were induced to differentiate, two sub-populations of cells were identified by two-color cytofluorography: the CD14+ (monocytoid) cells all expressed IFI 16, whereas the CD14- (polymorphonuclear precursor) cells did not.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'The strongest expression of IFI 16 was in the cells staining brightest for CD14, whereas depletion of CD14+ monocytoid cells from mixed monocytic/granulocytic cultures largely abolished IFI 16-stained cells.', answer the user's query. |
What is the biomedical concept corresponding to 'cd14'? | [
"cd14 molecule (homo sapiens)",
"cd14 (homo sapiens) (cd14 molecule (homo sapiens))"
] | [
"cd14 molecule (gallus gallus)",
"cd14 antigen (mus musculus)",
"cd14 (homo sapiens) (nadh:ubiquinone oxidoreductase subunit a2 (homo sapiens))",
"cd14 (mus musculus)",
"cd14 (oryctolagus cuniculus)",
"cd14 molecule (oryctolagus cuniculus)",
"cd142 (homo sapiens)",
"cd14 (gallus gallus)",
"cd141 (ho... | Given the context 'The strongest expression of IFI 16 was in the cells staining brightest for CD14, whereas depletion of CD14+ monocytoid cells from mixed monocytic/granulocytic cultures largely abolished IFI 16-stained cells.', answer the user's query. |
What is the biomedical concept corresponding to 'cd14'? | [
"cd14 molecule (homo sapiens)",
"cd14 (homo sapiens) (cd14 molecule (homo sapiens))"
] | [
"cd14 molecule (gallus gallus)",
"cd14 antigen (mus musculus)",
"cd14 (homo sapiens) (nadh:ubiquinone oxidoreductase subunit a2 (homo sapiens))",
"cd14 (mus musculus)",
"cd14 (oryctolagus cuniculus)",
"cd14 molecule (oryctolagus cuniculus)",
"cd142 (homo sapiens)",
"cd14 (gallus gallus)",
"cd141 (ho... | Given the context 'The strongest expression of IFI 16 was in the cells staining brightest for CD14, whereas depletion of CD14+ monocytoid cells from mixed monocytic/granulocytic cultures largely abolished IFI 16-stained cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'The strongest expression of IFI 16 was in the cells staining brightest for CD14, whereas depletion of CD14+ monocytoid cells from mixed monocytic/granulocytic cultures largely abolished IFI 16-stained cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'Furthermore, in eight independent colony-forming assays, the number of IFI 16+ cells correlated closely with the numbers of monocyte precursors identified morphologically (R2 = 0.99), but was unrelated to the numbers of myelocytes, promyelocytes, and metamyelocytes; nor was IFI 16 expressed by erythroid or eosinophil precursors.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'Furthermore, in eight independent colony-forming assays, the number of IFI 16+ cells correlated closely with the numbers of monocyte precursors identified morphologically (R2 = 0.99), but was unrelated to the numbers of myelocytes, promyelocytes, and metamyelocytes; nor was IFI 16 expressed by erythroid or eosinophil precursors.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'We conclude that IFI 16 is expressed in CD34+ and monocytoid daughter cells, but is rapidly and markedly down-regulated at the corresponding stages of polymorphonuclear and erythroid development.', answer the user's query. |
What is the biomedical concept corresponding to 'cd34'? | [
"cd34 molecule (homo sapiens)",
"cd34 (homo sapiens) (cd34 molecule (homo sapiens))"
] | [
"cd344 (homo sapiens)",
"cd34 molecule (gallus gallus)",
"cd340 (homo sapiens)",
"cd34 molecule (rattus norvegicus)",
"cd349 (homo sapiens)",
"cd34 antigen (mus musculus)",
"cd34 (gallus gallus)",
"cd34 (mus musculus)",
"cd34 (sus scrofa)",
"cd34 molecule (sus scrofa)"
] | Given the context 'We conclude that IFI 16 is expressed in CD34+ and monocytoid daughter cells, but is rapidly and markedly down-regulated at the corresponding stages of polymorphonuclear and erythroid development.', answer the user's query. |
What is the biomedical concept corresponding to 'ifi 16'? | [
"ifi16 (homo sapiens)",
"interferon gamma inducible protein 16 (homo sapiens)"
] | [
"ifi17 (homo sapiens)",
"ifi16 (mus musculus)",
"ifi6 (homo sapiens)",
"ifi15 (homo sapiens)",
"ifi27 (homo sapiens)",
"ifi10 (homo sapiens)",
"ifi16 (sus scrofa)",
"ifi4 (homo sapiens)",
"ifi27 (mus musculus) (interferon, alpha-inducible protein 27 (mus musculus))",
"ifi11 (homo sapiens)"
] | Given the context 'This differential expression of IFI 16 in myeloid precursor subpopulations and its perceived molecular properties are consistent with a possible role in regulating myelopoiesis.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'A novel candidate oncogene, MCT-1, is involved in cell cycle progression.
', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'We termed this novel gene with multiple copies in a T-cell malignancy as MCT-1.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'MCT-1 was localized to the long arm of chromosome Xq22-24 by flourescence in situ hybridization analysis.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclin h'? | [
"cyclin h (homo sapiens)",
"p34 (homo sapiens) (cyclin h (homo sapiens))",
"p37 (homo sapiens) (cyclin h (homo sapiens))",
"ccnh (homo sapiens)",
"cak (homo sapiens) (cyclin h (homo sapiens))"
] | [
"cyclin h (drosophila melanogaster)",
"cyclin-h (caenorhabditis elegans)",
"cyclin c (homo sapiens)",
"cyclin f (homo sapiens)",
"cyclin g (drosophila melanogaster)",
"cyclin h (gallus gallus)",
"cyclinc (drosophila melanogaster)",
"cycline (drosophila melanogaster)",
"cyclin h (mus musculus)",
"c... | Given the context 'Although there was no significant homology at the primary sequence level, there was a limited degree of amino acid homology with a domain of cyclin H that appears to specify protein-protein complexes.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'This relationship between MCT-1 and cyclin H implied a potential role for MCT-1 in cell cycle regulation.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclin h'? | [
"cyclin h (homo sapiens)",
"p34 (homo sapiens) (cyclin h (homo sapiens))",
"p37 (homo sapiens) (cyclin h (homo sapiens))",
"ccnh (homo sapiens)",
"cak (homo sapiens) (cyclin h (homo sapiens))"
] | [
"cyclin h (drosophila melanogaster)",
"cyclin-h (caenorhabditis elegans)",
"cyclin c (homo sapiens)",
"cyclin f (homo sapiens)",
"cyclin g (drosophila melanogaster)",
"cyclin h (gallus gallus)",
"cyclinc (drosophila melanogaster)",
"cycline (drosophila melanogaster)",
"cyclin h (mus musculus)",
"c... | Given the context 'This relationship between MCT-1 and cyclin H implied a potential role for MCT-1 in cell cycle regulation.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'This relationship between MCT-1 and cyclin H implied a potential role for MCT-1 in cell cycle regulation.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'Overexpression of MCT-1 increased the proliferative rate of cells by decreasing the length of the G1 phase without a reciprocal increase in the S and G2-M phases.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'Therefore, we investigated the transforming ability of MCT-1 overexpression using soft agar growth assays and demonstrated that only MCT-1-overexpressing cells were able to establish colonies.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'Therefore, we investigated the transforming ability of MCT-1 overexpression using soft agar growth assays and demonstrated that only MCT-1-overexpressing cells were able to establish colonies.', answer the user's query. |
What is the biomedical concept corresponding to 'mct-1'? | [
"mct-1 (homo sapiens)"
] | [
"mct-1 (drosophila melanogaster)",
"mct1 (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"mct1 (mus musculus) (solute carrier family 16 (monocarboxylic acid transporters), member 1 (mus musculus))",
"mct (homo sapiens) (solute carrier family 16 member 1 (homo sapiens))",
"slc16a1 (homo s... | Given the context 'Taken together, MCT-1 is a novel candidate oncogene with homology to a protein-protein binding domain of cyclin H.', answer the user's query. |
What is the biomedical concept corresponding to 'cyclin h'? | [
"cyclin h (homo sapiens)",
"p34 (homo sapiens) (cyclin h (homo sapiens))",
"p37 (homo sapiens) (cyclin h (homo sapiens))",
"ccnh (homo sapiens)",
"cak (homo sapiens) (cyclin h (homo sapiens))"
] | [
"cyclin h (drosophila melanogaster)",
"cyclin-h (caenorhabditis elegans)",
"cyclin c (homo sapiens)",
"cyclin f (homo sapiens)",
"cyclin g (drosophila melanogaster)",
"cyclin h (gallus gallus)",
"cyclinc (drosophila melanogaster)",
"cycline (drosophila melanogaster)",
"cyclin h (mus musculus)",
"c... | Given the context 'Taken together, MCT-1 is a novel candidate oncogene with homology to a protein-protein binding domain of cyclin H.', answer the user's query. |
What is the biomedical concept corresponding to 'akr1c3'? | [
"akr1c3 (homo sapiens)",
"aldo-keto reductase family 1 member c3 (homo sapiens)"
] | [
"akr1c1 (homo sapiens)",
"akr1c2 (homo sapiens)",
"akr1c4 (homo sapiens)",
"akr1r1b7 (homo sapiens)",
"akr1c-pseudo (homo sapiens)",
"akr1b1 (homo sapiens)",
"akr1e2 (homo sapiens)",
"akr1c8 (homo sapiens)",
"akr1cl1 (homo sapiens)",
"akr1b12 (homo sapiens)"
] | Given the context 'Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity.
', answer the user's query. |
What is the biomedical concept corresponding to 'akr1c3'? | [
"akr1c3 (homo sapiens)",
"aldo-keto reductase family 1 member c3 (homo sapiens)"
] | [
"akr1c1 (homo sapiens)",
"akr1c2 (homo sapiens)",
"akr1c4 (homo sapiens)",
"akr1r1b7 (homo sapiens)",
"akr1c-pseudo (homo sapiens)",
"akr1b1 (homo sapiens)",
"akr1e2 (homo sapiens)",
"akr1c8 (homo sapiens)",
"akr1cl1 (homo sapiens)",
"akr1b12 (homo sapiens)"
] | Given the context 'The properties of AKR1C3 have not been fully characterized compared to the other isoforms.', answer the user's query. |
What is the biomedical concept corresponding to 'akr1c3'? | [
"akr1c3 (homo sapiens)",
"aldo-keto reductase family 1 member c3 (homo sapiens)"
] | [
"akr1c1 (homo sapiens)",
"akr1c2 (homo sapiens)",
"akr1c4 (homo sapiens)",
"akr1r1b7 (homo sapiens)",
"akr1c-pseudo (homo sapiens)",
"akr1b1 (homo sapiens)",
"akr1e2 (homo sapiens)",
"akr1c8 (homo sapiens)",
"akr1cl1 (homo sapiens)",
"akr1b12 (homo sapiens)"
] | Given the context 'In addition, a cDNA that shows more than 99% homology with AKR1C3 cDNA has been cloned from human myeloblasts.', answer the user's query. |
What is the biomedical concept corresponding to 'akr1c3'? | [
"akr1c3 (homo sapiens)",
"aldo-keto reductase family 1 member c3 (homo sapiens)"
] | [
"akr1c1 (homo sapiens)",
"akr1c2 (homo sapiens)",
"akr1c4 (homo sapiens)",
"akr1r1b7 (homo sapiens)",
"akr1c-pseudo (homo sapiens)",
"akr1b1 (homo sapiens)",
"akr1e2 (homo sapiens)",
"akr1c8 (homo sapiens)",
"akr1cl1 (homo sapiens)",
"akr1b12 (homo sapiens)"
] | Given the context 'The recombinant AKR1C3 prepared by site-directed mutagenesis of DBDH also showed the same properties as the wild-type DBDH.', answer the user's query. |
What is the biomedical concept corresponding to 'akr1c3'? | [
"akr1c3 (homo sapiens)",
"aldo-keto reductase family 1 member c3 (homo sapiens)"
] | [
"akr1c1 (homo sapiens)",
"akr1c2 (homo sapiens)",
"akr1c4 (homo sapiens)",
"akr1r1b7 (homo sapiens)",
"akr1c-pseudo (homo sapiens)",
"akr1b1 (homo sapiens)",
"akr1e2 (homo sapiens)",
"akr1c8 (homo sapiens)",
"akr1cl1 (homo sapiens)",
"akr1b12 (homo sapiens)"
] | Given the context 'Analyses of expression of mRNAs for DBDH and AKR1C3 by reverse transcription-PCR indicated that only one mRNA species for DBDH is expressed in 33 human specimens of liver, kidney, lung, brain, heart, spleen, adrenal gland, small intestine, placenta, prostate, and testis.', answer the user's query. |
What is the biomedical concept corresponding to 'akr1c3'? | [
"akr1c3 (homo sapiens)",
"aldo-keto reductase family 1 member c3 (homo sapiens)"
] | [
"akr1c1 (homo sapiens)",
"akr1c2 (homo sapiens)",
"akr1c4 (homo sapiens)",
"akr1r1b7 (homo sapiens)",
"akr1c-pseudo (homo sapiens)",
"akr1b1 (homo sapiens)",
"akr1e2 (homo sapiens)",
"akr1c8 (homo sapiens)",
"akr1cl1 (homo sapiens)",
"akr1b12 (homo sapiens)"
] | Given the context 'These results suggest that AKR1C3 acts as prostaglandin D2 11-ketoreductase, and that its principal gene in the human has a coding region represented by DBDH cDNA.', answer the user's query. |
What is the biomedical concept corresponding to 'hakr e'? | [
"hakrb (homo sapiens)",
"hakre (homo sapiens)"
] | [
"hakrc (homo sapiens)",
"hakra (homo sapiens)",
"hakrd (homo sapiens)",
"ackr3 (homo sapiens)",
"ackr6 (homo sapiens)",
"ackr2 (homo sapiens)",
"ackr1 (homo sapiens)",
"ackr4 (homo sapiens)",
"hdkr (homo sapiens)",
"hakrd (xenopus laevis) (aldo-keto reductase family 1, member c2 l homeolog (xenopu... | Given the context 'In this study, we have identified a previously unclassified aldoketoreductase family member (termed HAKR e) that is expressed in HL60 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'hakr e'? | [
"hakrb (homo sapiens)",
"hakre (homo sapiens)"
] | [
"hakrc (homo sapiens)",
"hakra (homo sapiens)",
"hakrd (homo sapiens)",
"ackr3 (homo sapiens)",
"ackr6 (homo sapiens)",
"ackr2 (homo sapiens)",
"ackr1 (homo sapiens)",
"ackr4 (homo sapiens)",
"hdkr (homo sapiens)",
"hakrd (xenopus laevis) (aldo-keto reductase family 1, member c2 l homeolog (xenopu... | Given the context 'HAKR e is dramatically and transiently up-regulated in HL60 cells within 24 h of exposure to ATRA, further supporting the proposition that a member(s) of this family of enzymes play(s) a role in controlling cell growth and/or differentiation.', answer the user's query. |
What is the biomedical concept corresponding to 'bradykinin'? | [
"bk (homo sapiens)",
"bdk (homo sapiens) (kininogen 1 (homo sapiens))",
"kininogen 1 (homo sapiens)"
] | [
"bradykinin (xenopus laevis) (bradykinin receptor b2 s homeolog (xenopus laevis))",
"bradykinin (xenopus tropicalis)",
"bradykinin (xenopus laevis) (bradykinin receptor b2 l homeolog (xenopus laevis))",
"kinin (drosophila melanogaster)",
"kallikrein b1 (rattus norvegicus)",
"kallikrein b1 (bos taurus)",
... | Given the context 'G protein-coupled receptors such as the receptors for bradykinin are present in low copy numbers in most natural cells.', answer the user's query. |
What is the biomedical concept corresponding to 'b1 receptor'? | [
"b1r (homo sapiens)",
"bradykinin receptor b1 (homo sapiens)",
"b1bkr (homo sapiens)",
"bkb1r (homo sapiens)"
] | [
"b1ar (homo sapiens)",
"bradykinin receptor b1 (bos taurus)",
"b-r1 (homo sapiens)",
"b2r (homo sapiens)",
"b1r (mus musculus)",
"bradykinin receptor b1 (gallus gallus)",
"adhesion g protein-coupled receptor b1 (bos taurus)",
"b1ar (rattus norvegicus)",
"bradykinin receptor b1 (danio rerio)",
"adh... | Given the context 'The B1 receptor failed to undergo ligand-induced phosphorylation.', answer the user's query. |
What is the biomedical concept corresponding to 'b2 receptor'? | [
"b2r (homo sapiens)",
"bradykinin receptor b2 (homo sapiens)",
"bdkrb2 (homo sapiens)"
] | [
"b2ar (homo sapiens)",
"b2r (sus scrofa)",
"bradykinin receptor b2 (bos taurus)",
"b1r (homo sapiens)",
"bradykinin receptor b2 (gallus gallus)",
"b2r (mus musculus)",
"adhesion g protein-coupled receptor b2 (bos taurus)",
"bradykinin receptor b1 (homo sapiens)",
"b2 (mus musculus) (bradykinin recep... | Given the context 'However the B2 receptor showed selective phosphorylation of a minor 38 kDa band and lack of phosphorylation of a dominant 33 kDa band, indicating that only a fraction of the receptor protein is functionally linked to the kinase pathway.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'Isolation of hMRE11B: failure to complement yeast mre11 defects due to species-specific protein interactions.
', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'We present the isolation of hMRE11B cDNA from a human HeLa cell cDNA library as an MRE11 homolog.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'Compared to the previously identified hMRE11, hMRE11B contains an additional 84bp sequence that results in a 28 amino-acid insertion close to the C-terminus.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'The expression pattern of hMRE11B in different tissues shows the presence of two mRNA species of approx.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'Overexpression of hMRE11B does not complement the alkylation sensitivity of the mre11 null and temperature-sensitive mutant strains.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'First, both Northern and Western analyses rule out the lack of hMRE11B transcription and/or translation in yeast.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'Second, we demonstrate that hMre11B, like the yeast Mre11 protein, dimerizes in vivo in a yeast two-hybrid system.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'This dimerization requires the C-terminal one-third of hMre11B protein, which includes the 28 amino acids absent in hMre11.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', answer the user's query. |
What is the biomedical concept corresponding to 'xrs2'? | [
"xrs2 (saccharomyces cerevisiae s288c)"
] | [
"xrg2 (homo sapiens)",
"xr2c (drosophila melanogaster)",
"xrp2 (homo sapiens)",
"xrn2 (drosophila melanogaster)",
"x-ray repair cross complementing 2 (drosophila melanogaster)",
"x-ray repair cross complementing 2 (homo sapiens)",
"xrn2 (homo sapiens)",
"xrn-2 (caenorhabditis elegans)",
"dna repair ... | Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', answer the user's query. |
What is the biomedical concept corresponding to 'xrs2'? | [
"xrs2 (saccharomyces cerevisiae s288c)"
] | [
"xrg2 (homo sapiens)",
"xr2c (drosophila melanogaster)",
"xrp2 (homo sapiens)",
"xrn2 (drosophila melanogaster)",
"x-ray repair cross complementing 2 (drosophila melanogaster)",
"x-ray repair cross complementing 2 (homo sapiens)",
"xrn2 (homo sapiens)",
"xrn-2 (caenorhabditis elegans)",
"dna repair ... | Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'We rule out the hypothesis that the lack of interaction and, in turn of complementation, is due to the absence of sequence homology at the C-terminal domain of hMre11B compared to the yeast Mre11.', answer the user's query. |
What is the biomedical concept corresponding to 'hmre11b'? | [
"hmre11b (homo sapiens)"
] | [
"olfactory receptor family 11 subfamily h member 4b (mus musculus)",
"olfactory receptor family 11 subfamily h member 2 (homo sapiens)",
"olfactory receptor family 11 subfamily h member 6 (mus musculus)",
"olfactory receptor family 11 subfamily h member 4 (mus musculus)",
"olfactory receptor family 11 subfa... | Given the context 'Instead, we propose that the C-terminus of hMre11B participates in protein-protein interaction and functions in a species-specific manner.', answer the user's query. |
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