instruction stringlengths 161 2.29k | input stringlengths 137 955 | response stringclasses 11
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<Instruct>: Given the context 'This method specifically amplifies sequences between Alu repeats from human DNA in somatic cell hybrids and yeast artificial chromosomes (YACs, 4).', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: mycoderma cerevisiae (aka saccharomyces cerevisiae)
B: candida/saccharomycetales (aka candida/saccharomycales clade)
C: torulaspora
D: saccharomycetes sp. (saccharomycete sp.) (aka saccharomycetes sp.)
E: hemiascomycetes (aka saccharomycetes)
F: saccharomyceta
G: pichiomycetes
H: zygotorulaspora
I: saccha... | A |
<Instruct>: Given the context 'Two new human specific Alu primers were used to generate DNA probes from a series of irradiation-reduced hybrids containing multiple human X chromosome fragments of 1-2000 kb on a hamster chromosome background (5; P.N.G., unpublished).', select the correct biomedical concept corresponding... | <Options>: A: primate (aka primates)
B: great apes (aka hominidae)
C: homo sapiens (human) (aka homo sapiens)
D: genus
E: homininae (homo/pan/gorilla group) (aka homininae)
F: macrobiotus sapiens
G: humans (aka homo)
H: neanderthal man (aka homo sapiens neanderthalensis)
I: anthropoides
J: mammals (aka mammalia)
K: Non... | C |
<Instruct>: Given the context 'Two new human specific Alu primers were used to generate DNA probes from a series of irradiation-reduced hybrids containing multiple human X chromosome fragments of 1-2000 kb on a hamster chromosome background (5; P.N.G., unpublished).', select the correct biomedical concept corresponding... | <Options>: A: macrobiotus sapiens
B: neanderthal man (aka homo sapiens neanderthalensis)
C: humans (aka homo)
D: kingdom
E: genus
F: mammals (aka mammalia)
G: homo sapiens (human) (aka homo sapiens)
H: hominoidea (apes (aka hominoidea))
I: hominidae (great apes) (aka hominidae)
J: homininae (homo/pan/gorilla group) (ak... | G |
<Instruct>: Given the context 'The Alu-PCR products were hybridized as a pool of probes to X-specific cosmid and YAC libraries, after
competitive reassociation with an excess of human DNA to both the library filters and radioactively labelled Alu-PCR products.', select the correct biomedical concept corresponding to... | <Options>: A: anthropoides
B: homo (humans) (aka homo)
C: genus
D: kingdom
E: mammals (aka mammalia)
F: homininae (homo/pan/gorilla group) (aka homininae)
G: neandertal man (aka homo sapiens neanderthalensis)
H: homo sapiens (human) (aka homo sapiens)
I: primate (aka primates)
J: macrobiotus sapiens
K: None of the abov... | H |
<Instruct>: Given the context 'METHODS
Two human Alu sequence primers were generated which were shown to be human specific; 3144 from the 3' end of Alu: 5'-GAGCGAGACTCCGTCTCAAA-3' and 2729 from the 5' end of Alu: 5'-GTGGATCACCTGAGGTCAGGAGTTC-3'.', select the correct biomedical concept corresponding to 'human'. Answe... | <Options>: A: anthropoides
B: gymnopleurus humanus
C: human (aka homo sapiens)
D: homininae (homo/pan/gorilla group) (aka homininae)
E: homo (humans) (aka homo)
F: primate (aka primates)
G: kingdom
H: hominidae (great apes) (aka hominidae)
I: macrobiotus sapiens
J: homo sapiens neanderthalensis (homo neanderthalensis) ... | C |
<Instruct>: Given the context 'METHODS
Two human Alu sequence primers were generated which were shown to be human specific; 3144 from the 3' end of Alu: 5'-GAGCGAGACTCCGTCTCAAA-3' and 2729 from the 5' end of Alu: 5'-GTGGATCACCTGAGGTCAGGAGTTC-3'.', select the correct biomedical concept corresponding to 'human'. Answe... | <Options>: A: great apes (aka hominidae)
B: human (aka homo sapiens)
C: homininae (homo/pan/gorilla group) (aka homininae)
D: macrobiotus sapiens
E: primate (aka primates)
F: gymnopleurus humanus
G: anthropoides
H: humans (aka homo)
I: kingdom
J: mammals (aka mammalia)
K: None of the above. | B |
<Instruct>: Given the context 'Chinese hamster DNA and no DNA PCR reactions were done to control for non-human products (data not shown).
', select the correct biomedical concept corresponding to 'chinese hamster'. Answer using one of the provided options. | <Options>: A: chinese hamsters (aka cricetulus griseus)
B: common hamster (aka cricetus cricetus)
C: hamster sp. (aka cricetinae gen. sp.)
D: syrian golden hamster (aka mesocricetus auratus)
E: gansu hamster (aka cansumys canus)
F: turkish hamster (aka mesocricetus brandti)
G: grey hamster (aka nothocricetulus migrator... | A |
<Instruct>: Given the context 'Chinese hamster DNA and no DNA PCR reactions were done to control for non-human products (data not shown).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: macrobiotus sapiens
B: kingdom
C: hominidae (great apes) (aka hominidae)
D: anthropoides
E: homininae (homo/pan/gorilla group) (aka homininae)
F: mammals (aka mammalia)
G: primate (aka primates)
H: homo sapiens (human) (aka homo sapiens)
I: gymnopleurus humanus
J: genus
K: None of the above. | H |
<Instruct>: Given the context 'The radioactively labelled pool of fragments was prehybridized with 37.5 ,^g of total human DNA and 12.5 tsg of hamster DNA immobilized on a cellulose support matrix, prepared as previously described (7).', select the correct biomedical concept corresponding to 'human'. Answer using one o... | <Options>: A: kingdom
B: mammals (aka mammalia)
C: primate (aka primates)
D: anthropoides
E: homo sapiens (human) (aka homo sapiens)
F: gymnopleurus humanus
G: great apes (aka hominidae)
H: macrobiotus sapiens
I: homininae (homo/pan/gorilla group) (aka homininae)
J: ape (aka hominoidea) (aka hominoidea)
K: None of the ... | E |
<Instruct>: Given the context 'I I
Figur 2a and 2b: Hybridization of Alu-PCR products generated with Alu primer 3144 from irradiation hybrid 48 to duplicate copies of 22 x22cm filters containing 9216 human X chromosome cosmids (8).', select the correct biomedical concept corresponding to 'human'. Answer using one of... | <Options>: A: macrobiotus sapiens
B: hominoidea (apes (aka hominoidea))
C: homo sapiens neanderthalensis (homo neanderthalensis) (aka homo sapiens neanderthalensis)
D: kingdom
E: gymnopleurus humanus
F: homo sapiens (human) (aka homo sapiens)
G: anthropoides
H: mammals (aka mammalia)
I: humans (aka homo)
J: genus
K: No... | F |
<Instruct>: Given the context 'Figure 1: A schematic diagram of the human X chromosome alongside the approximate cytogenetic location of fragments identified in nine irradiation hybrids (numbers across the top).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: hominoidea (apes (aka hominoidea))
B: genus
C: gymnopleurus humanus
D: anthropoides
E: homo sapiens (human) (aka homo sapiens)
F: homo (humans) (aka homo)
G: hominidae (great apes) (aka hominidae)
H: neandertal man (aka homo sapiens neanderthalensis)
I: homininae (homo/pan/gorilla group) (aka homininae)
J... | E |
<Instruct>: Given the context 'The human X fragments were identified by hybridization of 27 known DNA markers (indicated by a black line; P.N.G, unpublished) or by cosmids in common with unique X chromosome probes in the reference library database (open boxes and Table 1).', select the correct biomedical concept corres... | <Options>: A: homo sapiens neanderthalensis (homo neanderthalensis) (aka homo sapiens neanderthalensis)
B: gymnopleurus humanus
C: great apes (aka hominidae)
D: genus
E: mammals (aka mammalia)
F: anthropoides
G: human (aka homo sapiens)
H: hominoidea (apes (aka hominoidea))
I: primate (aka primates)
J: humans (aka homo... | G |
<Instruct>: Given the context 'denatured and sheared total human DNA in 50% formamide, 4XSSC, 0.05 M sodium phosphate pH 7.2, 0.001 M EDTA, 10% dextran sulphate, 1.0% SDS, 50 isg/ml denatured salmon sperm DNA and OxDenhardt's solution.', select the correct biomedical concept corresponding to 'human'. Answer using one o... | <Options>: A: homo (humans) (aka homo)
B: great apes (aka hominidae)
C: primate (aka primates)
D: gymnopleurus humanus
E: macrobiotus sapiens
F: kingdom
G: homo sapiens neanderthalensis (homo neanderthalensis) (aka homo sapiens neanderthalensis)
H: human (aka homo sapiens)
I: genus
J: homininae (homo/pan/gorilla group)... | H |
<Instruct>: Given the context 'The radioactively labelled Alu-PCR products were denatured and added to fresh
hybridization solution without human DNA competitor at 1 x 106
cpm/ml and hybridized at 42?C for 16 hours.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided... | <Options>: A: genus
B: macrobiotus sapiens
C: primate (aka primates)
D: gymnopleurus humanus
E: homo (humans) (aka homo)
F: homo sapiens (human) (aka homo sapiens)
G: kingdom
H: mammals (aka mammalia)
I: anthropoides
J: homininae (homo/pan/gorilla group) (aka homininae)
K: None of the above. | F |
<Instruct>: Given the context 'For each hybridization, two sets of duplicate cosmid filters were used from the ICRF reference library system (8), each containing 9216 flow-sorted human X chromosome cosmid clones or approximately 2 chromosome equivalents on a 22 x 22 cm filter (9).', select the correct biomedical concep... | <Options>: A: gymnopleurus humanus
B: homo (humans) (aka homo)
C: mammals (aka mammalia)
D: primate (aka primates)
E: genus
F: human (aka homo sapiens)
G: great apes (aka hominidae)
H: anthropoides
I: apes (aka hominoidea) (aka hominoidea)
J: homininae (homo/pan/gorilla group) (aka homininae)
K: None of the above. | F |
<Instruct>: Given the context 'RESULTS
A panel of 195 X chromosome irradiation hybrids was constructed (50,000 rads) and characterized by DNA hybridization using 27 X chromosome markers and flourescence in situ hybridization using total human DNA as probe (Benham et al., 1989; P.N.G., unpublished).', select the corr... | <Options>: A: mammals (aka mammalia)
B: humans (aka homo)
C: homininae (homo/pan/gorilla group) (aka homininae)
D: genus
E: homo sapiens (human) (aka homo sapiens)
F: primate (aka primates)
G: hominoidea (apes (aka hominoidea))
H: kingdom
I: great apes (aka hominidae)
J: anthropoides
K: None of the above. | E |
<Instruct>: Given the context 'All nine hybrids were used in PCR reactions with 3'-Alu primer 3144 and two were used with 5'-Alu
Figure 3: Hybridization of Alu-PCR products generated with Alu primer 3144 from irradiation hybrid 54 to a filter containing 420 YAC clones from the human X chromosome.', select the correc... | <Options>: A: homo sapiens neanderthalensis (homo neanderthalensis) (aka homo sapiens neanderthalensis)
B: mammals (aka mammalia)
C: hominidae (great apes) (aka hominidae)
D: anthropoides
E: primate (aka primates)
F: macrobiotus sapiens
G: kingdom
H: ape (aka hominoidea) (aka hominoidea)
I: homo sapiens (human) (aka ho... | I |
<Instruct>: Given the context 'Example hybridizations to a human X chromosome cosmid filter in Fig 2 shows the intensity and reliability of positive clones identified on duplicate filters with Alu-PCR products from the same irradiation hybrid (48) and the independence of clones identified with Alu-PCR products from a d... | <Options>: A: gymnopleurus humanus
B: hominoidea (apes (aka hominoidea))
C: mammals (aka mammalia)
D: human (aka homo sapiens)
E: primate (aka primates)
F: neanderthal man (aka homo sapiens neanderthalensis)
G: homininae (homo/pan/gorilla group) (aka homininae)
H: anthropoides
I: hominidae (great apes) (aka hominidae)
... | D |
<Instruct>: Given the context 'Fig 3 shows a single positive YAC clone after hybridization of Alu-PCR products from irradiation hybrid 54 to a filter containing about 420 YAC clones specific for the human X chromosome.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provide... | <Options>: A: humans (aka homo)
B: kingdom
C: macrobiotus sapiens
D: mammals (aka mammalia)
E: human (aka homo sapiens)
F: homininae (homo/pan/gorilla group) (aka homininae)
G: neanderthal man (aka homo sapiens neanderthalensis)
H: hominidae (great apes) (aka hominidae)
I: anthropoides
J: gymnopleurus humanus
K: None o... | E |
<Instruct>: Given the context 'Since only 27 probes from the X chromosome were used to initially characterize the hybrids and the length of individual human fragments in the irradiation hybrids is about 1000-5000 kb, many regions could have been undetected in the original analysis.', select the correct biomedical conce... | <Options>: A: genus
B: apes (aka hominoidea) (aka hominoidea)
C: kingdom
D: gymnopleurus humanus
E: mammals (aka mammalia)
F: human (aka homo sapiens)
G: hominidae (great apes) (aka hominidae)
H: homininae (homo/pan/gorilla group) (aka homininae)
I: humans (aka homo)
J: macrobiotus sapiens
K: None of the above. | F |
<Instruct>: Given the context 'However, since the exact length of the human DNA fragments for each hybrid and the spacing of Alu-PCR products along the chromosome is not known, it is difficult to directly correlate the number of target cosmids to the DNA content of the hybrids.
', select the correct biomedical conce... | <Options>: A: homo (humans) (aka homo)
B: hominidae (great apes) (aka hominidae)
C: mammals (aka mammalia)
D: macrobiotus sapiens
E: apes (aka hominoidea) (aka hominoidea)
F: homo sapiens (human) (aka homo sapiens)
G: kingdom
H: gymnopleurus humanus
I: homininae (homo/pan/gorilla group) (aka homininae)
J: genus
K: None... | F |
<Instruct>: Given the context 'The dissection of a total genomic YAC library by this method may be more efficient than generating chromosome specific YAC libraries from somatic cell hybrids (usually a haploid human chromosome on a diploid or greater rodent background) or flow-sorted chromosomes, because of the low tran... | <Options>: A: gymnopleurus humanus
B: great apes (aka hominidae)
C: humans (aka homo)
D: anthropoides
E: homininae (homo/pan/gorilla group) (aka homininae)
F: genus
G: neandertal man (aka homo sapiens neanderthalensis)
H: mammals (aka mammalia)
I: ape (aka hominoidea) (aka hominoidea)
J: homo sapiens (human) (aka homo ... | J |
<Instruct>: Given the context 'The dissection of a total genomic YAC library by this method may be more efficient than generating chromosome specific YAC libraries from somatic cell hybrids (usually a haploid human chromosome on a diploid or greater rodent background) or flow-sorted chromosomes, because of the low tran... | <Options>: A: saccharomyceta
B: zygotorulaspora
C: baker's yeast (aka saccharomyces cerevisiae)
D: pichiomycetes
E: saccharomycotina (budding yeasts & others) (aka saccharomycotina)
F: candida/saccharomycetales (aka candida/saccharomycales clade)
G: torulaspora
H: saccharomyces cerevisiae or paradoxus (aka saccharomyce... | C |
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