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<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; type i interferon; cd8alpha] <Options>: A: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) B: cd8a (rattus norvegicus) (aka cd8 subunit alpha) C: interferon, alpha 1 (rattus norvegicus) (aka interferon, alpha 1) D: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha) E: ifnb1 (homo sapiens) (aka interferon beta 1) F: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) G: icsbp (mus musculus) (aka interferon regulatory factor 8) H: cd8b1 (mus musculus) (aka cd8 subunit beta 1) I: interferon alpha 1 (mus musculus) (aka interferon alpha 1) J: ilbp (mus musculus) (aka fatty acid binding protein 6) K: cd8alpha (homo sapiens) (aka cd8 subunit alpha) L: ilbp (homo sapiens) (aka fatty acid binding protein 6) M: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) N: interferon alpha 1 (homo sapiens) (aka interferon alpha 1) O: ifnb1 (mus musculus) (aka interferon beta 1, fibroblast) P: None of the above.
[G; O; D]
<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; type i interferon; cd8alpha] <Options>: A: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) B: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) C: cd8a (rattus norvegicus) (aka cd8 subunit alpha) D: icsbp (mus musculus) (aka interferon regulatory factor 8) E: interferon, type 1, cluster (homo sapiens) (aka interferon, type 1, cluster) F: cd8b1 (mus musculus) (aka cd8 subunit beta 1) G: illbp (mus musculus) (aka fatty acid binding protein 6) H: ilbp (homo sapiens) (aka fatty acid binding protein 6) I: ifnb1 (homo sapiens) (aka interferon beta 1) J: interferon alpha 1 (mus musculus) (aka interferon alpha 1) K: ifnb1 (mus musculus) (aka interferon beta 1, fibroblast) L: cd8a (homo sapiens) (aka cd8 subunit alpha) M: interferon, alpha 1 (rattus norvegicus) (aka interferon, alpha 1) N: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) O: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha) P: None of the above.
[D; K; O]
<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; type i interferon; cd8alpha] <Options>: A: icsbp1 (mus musculus) (aka interferon regulatory factor 8) B: interferon alpha 1 (mus musculus) (aka interferon alpha 1) C: ifnb1 (homo sapiens) (aka interferon beta 1) D: ilbp (mus musculus) (aka fatty acid binding protein 6) E: cd8a (rattus norvegicus) (aka cd8 subunit alpha) F: ilbp (homo sapiens) (aka fatty acid binding protein 6) G: ifng (homo sapiens) (aka interferon gamma) H: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha) I: ifn1@ (homo sapiens) (aka interferon, type 1, cluster) J: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) K: cd8b1 (mus musculus) (aka cd8 subunit beta 1) L: cd8a (homo sapiens) (aka cd8 subunit alpha) M: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) N: ifnb1 (mus musculus) (aka interferon beta 1, fibroblast) O: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) P: None of the above.
[A; N; H]
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [interferon (ifn) consensus sequence-binding protein; icsbp; transcription factor] <Options>: A: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) B: tcf1 (homo sapiens) (aka hnf1 homeobox a) C: sine oculis binding protein (mus musculus) (aka sine oculis binding protein) D: ilbp (mus musculus) (aka fatty acid binding protein 6) E: ns1bp (homo sapiens) (aka influenza virus ns1a binding protein) F: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) G: runx2 (homo sapiens) (aka runx family transcription factor 2) H: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) I: tcf (homo sapiens) (aka hepatocyte nuclear factor 4 alpha) J: tcf-1 (homo sapiens) (transcription factor 7 (homo sapiens)) (aka transcription factor 7) K: ilbp (homo sapiens) (aka fatty acid binding protein 6) L: icsbp (mus musculus) (aka interferon regulatory factor 8) M: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) N: tff1 (homo sapiens) (aka trefoil factor 1) O: None of the above.
[L; L; O]
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [interferon (ifn) consensus sequence-binding protein; icsbp; transcription factor] <Options>: A: trans-acting transcription factor 1 (mus musculus) (aka trans-acting transcription factor 1) B: ns1bp (homo sapiens) (aka influenza virus ns1a binding protein) C: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) D: illbp (mus musculus) (aka fatty acid binding protein 6) E: tcf1 (mus musculus) (transcription factor 7, t cell specific (mus musculus)) (aka transcription factor 7, t cell specific) F: tff1 (mus musculus) (aka trefoil factor 1) G: tcf (homo sapiens) (aka hepatocyte nuclear factor 4 alpha) H: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) I: ilbp (homo sapiens) (aka fatty acid binding protein 6) J: runx2 (homo sapiens) (aka runx family transcription factor 2) K: sine oculis binding protein (mus musculus) (aka sine oculis binding protein) L: icsbp (mus musculus) (aka interferon regulatory factor 8) M: None of the above.
[L; L; M]
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [interferon (ifn) consensus sequence-binding protein; icsbp; transcription factor] <Options>: A: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) B: ilbp (homo sapiens) (aka fatty acid binding protein 6) C: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) D: icsbp1 (mus musculus) (aka interferon regulatory factor 8) E: ns1bp (homo sapiens) (aka influenza virus ns1a binding protein) F: tcf1 (mus musculus) (hnf1 homeobox a (mus musculus)) (aka hnf1 homeobox a) G: ilbp (mus musculus) (aka fatty acid binding protein 6) H: runx2 (homo sapiens) (aka runx family transcription factor 2) I: tcf-1 (homo sapiens) (transcription factor 7 (homo sapiens)) (aka transcription factor 7) J: cold inducible rna binding protein (mus musculus) (aka cold inducible rna binding protein) K: tff1 (mus musculus) (aka trefoil factor 1) L: sine oculis binding protein (mus musculus) (aka sine oculis binding protein) M: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) N: icsbp (mus musculus) (aka interferon regulatory factor 8) O: trans-acting transcription factor 1 (mus musculus) (aka trans-acting transcription factor 1) P: None of the above.
[N; D; P]
<Instruct>: Given the context 'In this study, we have characterized the phenotype and activation pattern of subsets of dendritic cells (DCs) in ICSBP(-/-) mice.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp] <Options>: A: ilbp (homo sapiens) (aka fatty acid binding protein 6) B: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) C: icsbp1 (mus musculus) (aka interferon regulatory factor 8) D: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) E: ilbp (mus musculus) (aka fatty acid binding protein 6) F: None of the above.
[C]
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ifn; icsbp; cd11c; b220] <Options>: A: ilbp (mus musculus) (aka fatty acid binding protein 6) B: cd20 (mus musculus) (aka membrane-spanning 4-domains, subfamily a, member 1) C: cd79a (mus musculus) (aka cd79a antigen (immunoglobulin-associated alpha)) D: cd64 (mus musculus) (aka fc receptor, igg, high affinity i) E: cd103 (homo sapiens) (aka integrin subunit alpha e) F: ifn1@ (homo sapiens) (aka interferon, type 1, cluster) G: ifna@ (homo sapiens) (aka interferon alpha 1) H: cd11c (mus musculus) (aka integrin alpha x) I: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) J: ilbp (homo sapiens) (aka fatty acid binding protein 6) K: cd45 (mus musculus) (aka protein tyrosine phosphatase receptor type c) L: ifng (homo sapiens) (aka interferon gamma) M: cd79a (homo sapiens) (aka cd79a molecule) N: cd45 (homo sapiens) (aka protein tyrosine phosphatase receptor type c) O: cd11c (homo sapiens) (aka integrin subunit alpha x) P: cd11b (homo sapiens) (aka integrin subunit alpha m) Q: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) R: icsbp (mus musculus) (aka interferon regulatory factor 8) S: ifnaa (mus musculus) (aka interferon alpha 15) T: ifng (mus musculus) (aka interferon gamma) U: None of the above.
[T; R; H; K]
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ifn; icsbp; cd11c; b220] <Options>: A: cd79a (homo sapiens) (aka cd79a molecule) B: ifna (homo sapiens) (interferon, type 1, cluster (homo sapiens)) (aka interferon, type 1, cluster) C: ifn-alpha (homo sapiens) (aka interferon alpha 1) D: cd20 (mus musculus) (aka membrane-spanning 4-domains, subfamily a, member 1) E: icsbp (homo sapiens) (aka interferon regulatory factor 8) F: b220 (mus musculus) (aka protein tyrosine phosphatase receptor type c) G: icsbp1 (mus musculus) (aka interferon regulatory factor 8) H: cd11b (homo sapiens) (aka integrin subunit alpha m) I: illbp (mus musculus) (aka fatty acid binding protein 6) J: cd45 (homo sapiens) (aka protein tyrosine phosphatase receptor type c) K: cd64 (mus musculus) (aka fc receptor, igg, high affinity i) L: ilbp (homo sapiens) (aka fatty acid binding protein 6) M: ifng (mus musculus) (aka interferon gamma) N: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) O: ifng (homo sapiens) (aka interferon gamma) P: cd79a (mus musculus) (aka cd79a antigen (immunoglobulin-associated alpha)) Q: ifnaa (mus musculus) (aka interferon alpha 15) R: cd11c (mus musculus) (aka integrin alpha x) S: cd1 (mus musculus) (cd1 antigen complex (mus musculus)) (aka cd1 antigen complex) T: cd11b (mus musculus) (aka integrin alpha m) U: None of the above.
[M; G; R; F]
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ifn; icsbp; cd11c; b220] <Options>: A: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) B: cd45r (homo sapiens) (aka protein tyrosine phosphatase receptor type c) C: icsbp (mus musculus) (aka interferon regulatory factor 8) D: cd1 (homo sapiens) (cd1a molecule (homo sapiens)) (aka cd1a molecule) E: cd103 (mus musculus) (aka integrin alpha e, epithelial-associated) F: cd79a antigen (immunoglobulin-associated alpha) (mus musculus) (aka cd79a antigen (immunoglobulin-associated alpha)) G: cd14 (mus musculus) (aka cd14 antigen) H: ilbp (mus musculus) (aka fatty acid binding protein 6) I: cd11c (mus musculus) (aka integrin alpha x) J: ifng (homo sapiens) (aka interferon gamma) K: ifnaa (mus musculus) (aka interferon alpha 15) L: cd11c (homo sapiens) (aka integrin subunit alpha x) M: ilbp (homo sapiens) (aka fatty acid binding protein 6) N: ifna (mus musculus) (aka interferon alpha complex region) O: cd45 (mus musculus) (aka protein tyrosine phosphatase receptor type c) P: ifng (mus musculus) (aka interferon gamma) Q: cd20 (mus musculus) (aka membrane-spanning 4-domains, subfamily a, member 1) R: cd79a (homo sapiens) (aka cd79a molecule) S: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) T: ifn (homo sapiens) (aka interferon alpha 1) U: None of the above.
[P; C; I; O]
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ifn; icsbp; cd11c; b220] <Options>: A: illbp (mus musculus) (aka fatty acid binding protein 6) B: cd79a (homo sapiens) (aka cd79a molecule) C: cd45r (mus musculus) (aka protein tyrosine phosphatase receptor type c) D: ifnaa (mus musculus) (aka interferon alpha 15) E: cd11c (mus musculus) (aka integrin alpha x) F: ifn-alpha (homo sapiens) (aka interferon alpha 1) G: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) H: ifng (homo sapiens) (aka interferon gamma) I: cd103 (mus musculus) (aka integrin alpha e, epithelial-associated) J: ilbp (homo sapiens) (aka fatty acid binding protein 6) K: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) L: interferon kappa (homo sapiens) (aka interferon kappa) M: cd14 (mus musculus) (aka cd14 antigen) N: cd79a (mus musculus) (aka cd79a antigen (immunoglobulin-associated alpha)) O: icsbp (mus musculus) (aka interferon regulatory factor 8) P: ifng (mus musculus) (aka interferon gamma) Q: cd20 (mus musculus) (aka membrane-spanning 4-domains, subfamily a, member 1) R: cd45 (homo sapiens) (aka protein tyrosine phosphatase receptor type c) S: cd11b (homo sapiens) (aka integrin subunit alpha m) T: cd1 (mus musculus) (cd1 antigen complex (mus musculus)) (aka cd1 antigen complex) U: None of the above.
[P; O; E; C]
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ly6c; cd11b] <Options>: A: cd11b (danio rerio) (aka integrin, alpha m (complement component 3 receptor 3 subunit), tandem duplicate 1) B: mac-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2) C: ly-c (mus musculus) (aka cd8 subunit beta 1) D: cd11b (homo sapiens) (aka integrin subunit alpha m) E: ly6 (mus musculus) (aka lymphocyte antigen 6 complex) F: ly67 (mus musculus) (aka lymphocyte antigen 6 family member e) G: ly6-c antigen (rattus norvegicus) (aka ly6-c antigen) H: ly6c (mus musculus) (aka lymphocyte antigen 6 family member c1) I: cd11b/cd18 (mus musculus) (aka integrin alpha m) J: cd11b (rattus norvegicus) (aka integrin subunit alpha m) K: None of the above.
[H; I]
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ly6c; cd11b] <Options>: A: ly6-c antigen (rattus norvegicus) (aka ly6-c antigen) B: cd11b (rattus norvegicus) (aka integrin subunit alpha m) C: ly6 (mus musculus) (aka lymphocyte antigen 6 complex) D: cd61 (homo sapiens) (aka integrin subunit beta 3) E: ly-c (mus musculus) (aka cd8 subunit beta 1) F: cd11b (ovis aries) (aka integrin subunit alpha m) G: mac-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2) H: ly6c1 (mus musculus) (aka lymphocyte antigen 6 family member c1) I: ly6g (mus musculus) (aka lymphocyte antigen 6 family member g) J: cd11b/cd18 (mus musculus) (aka integrin alpha m) K: None of the above.
[H; J]
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [cd11c; icsbp; type i ifns] <Options>: A: ifnb1 (homo sapiens) (aka interferon beta 1) B: cd11c (homo sapiens) (aka integrin subunit alpha x) C: interferon, type 1, cluster (homo sapiens) (aka interferon, type 1, cluster) D: cd103 (mus musculus) (aka integrin alpha e, epithelial-associated) E: cd103 (homo sapiens) (aka integrin subunit alpha e) F: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) G: ifnb1 (mus musculus) (aka interferon beta 1, fibroblast) H: ilbp (homo sapiens) (aka fatty acid binding protein 6) I: ilbp (mus musculus) (aka fatty acid binding protein 6) J: ifn (homo sapiens) (aka interferon alpha 1) K: icsbp (mus musculus) (aka interferon regulatory factor 8) L: cd64 (mus musculus) (aka fc receptor, igg, high affinity i) M: stat1 (mus musculus) (aka signal transducer and activator of transcription 1) N: cd11c (mus musculus) (aka integrin alpha x) O: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) P: None of the above.
[N; K; G]
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [cd11c; icsbp; type i ifns] <Options>: A: cd11b (homo sapiens) (aka integrin subunit alpha m) B: cd11c (mus musculus) (aka integrin alpha x) C: cd1 (homo sapiens) (cd1a molecule (homo sapiens)) (aka cd1a molecule) D: ifn1@ (homo sapiens) (aka interferon, type 1, cluster) E: ifng (homo sapiens) (aka interferon gamma) F: stat1 (mus musculus) (aka signal transducer and activator of transcription 1) G: ilbp (homo sapiens) (aka fatty acid binding protein 6) H: cd11c (homo sapiens) (aka integrin subunit alpha x) I: ifn (homo sapiens) (aka interferon alpha 1) J: icsbp (mus musculus) (aka interferon regulatory factor 8) K: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) L: ilbp (mus musculus) (aka fatty acid binding protein 6) M: ifnb1 (mus musculus) (aka interferon beta 1, fibroblast) N: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) O: cd103 (homo sapiens) (aka integrin subunit alpha e) P: None of the above.
[B; J; M]
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [cd11c; icsbp; type i ifns] <Options>: A: cd11c (homo sapiens) (aka integrin subunit alpha x) B: cd14 (mus musculus) (aka cd14 antigen) C: ifn (homo sapiens) (aka interferon alpha 1) D: stat1 (mus musculus) (aka signal transducer and activator of transcription 1) E: ilbp (mus musculus) (aka fatty acid binding protein 6) F: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) G: cd11c (mus musculus) (aka integrin alpha x) H: ifnb1 (mus musculus) (aka interferon beta 1, fibroblast) I: cd103 (mus musculus) (aka integrin alpha e, epithelial-associated) J: cd1 (mus musculus) (cd1 antigen complex (mus musculus)) (aka cd1 antigen complex) K: ifnb1 (homo sapiens) (aka interferon beta 1) L: ifna (mus musculus) (aka interferon alpha complex region) M: icsbp (mus musculus) (aka interferon regulatory factor 8) N: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) O: ilbp (homo sapiens) (aka fatty acid binding protein 6) P: None of the above.
[G; M; H]
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; cd8alpha] <Options>: A: icsbp (mus musculus) (aka interferon regulatory factor 8) B: ilbp (homo sapiens) (aka fatty acid binding protein 6) C: cd8 (homo sapiens) (aka cd8 subunit alpha) D: cd8a (mus musculus) (aka cd8 subunit alpha) E: cd8b1 (mus musculus) (aka cd8 subunit beta 1) F: ilbp (mus musculus) (aka fatty acid binding protein 6) G: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) H: icsbp (homo sapiens) (aka interferon regulatory factor 8) I: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) J: cd8 subunit alpha (rattus norvegicus) (aka cd8 subunit alpha) K: None of the above.
[A; D]
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; cd8alpha] <Options>: A: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) B: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) C: cd8b1 (mus musculus) (aka cd8 subunit beta 1) D: ilbp (homo sapiens) (aka fatty acid binding protein 6) E: ilbp (mus musculus) (aka fatty acid binding protein 6) F: icsbp (mus musculus) (aka interferon regulatory factor 8) G: icsbp (homo sapiens) (aka interferon regulatory factor 8) H: cd8 subunit alpha (rattus norvegicus) (aka cd8 subunit alpha) I: cd8 (homo sapiens) (aka cd8 subunit alpha) J: None of the above.
[F; J]
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; cd8alpha] <Options>: A: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha) B: cd8b1 (mus musculus) (aka cd8 subunit beta 1) C: ilbp (mus musculus) (aka fatty acid binding protein 6) D: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) E: icsbp (homo sapiens) (aka interferon regulatory factor 8) F: cd8 (homo sapiens) (aka cd8 subunit alpha) G: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) H: ilbp (homo sapiens) (aka fatty acid binding protein 6) I: cd8 subunit alpha (rattus norvegicus) (aka cd8 subunit alpha) J: icsbp1 (mus musculus) (aka interferon regulatory factor 8) K: None of the above.
[J; A]
<Instruct>: Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; cd8alpha] <Options>: A: illbp (mus musculus) (aka fatty acid binding protein 6) B: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha) C: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) D: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) E: cd8a (homo sapiens) (aka cd8 subunit alpha) F: cd8 subunit alpha (rattus norvegicus) (aka cd8 subunit alpha) G: cd8b1 (mus musculus) (aka cd8 subunit beta 1) H: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) I: ilbp (homo sapiens) (aka fatty acid binding protein 6) J: icsbp (mus musculus) (aka interferon regulatory factor 8) K: None of the above.
[J; B]
<Instruct>: Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; cd8alpha] <Options>: A: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) B: cd8alpha (homo sapiens) (aka cd8 subunit alpha) C: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) D: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) E: ilbp (homo sapiens) (aka fatty acid binding protein 6) F: cd8a (rattus norvegicus) (aka cd8 subunit alpha) G: cd8b1 (mus musculus) (aka cd8 subunit beta 1) H: ilbp (mus musculus) (aka fatty acid binding protein 6) I: icsbp (mus musculus) (aka interferon regulatory factor 8) J: cd8a (mus musculus) (aka cd8 subunit alpha) K: None of the above.
[I; J]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [intercellular adhesion molecule [icam]-1; cd40; cd80; cd86] <Options>: A: p50 (homo sapiens) (cd40 molecule (homo sapiens)) (aka cd40 molecule) B: cd40l (homo sapiens) (aka cd40 ligand) C: cd80 molecule (homo sapiens) (aka cd80 molecule) D: cd86 molecule (rattus norvegicus) (aka cd86 molecule) E: cd86 (mus musculus) (aka cd86 antigen) F: cd51 (mus musculus) (aka integrin alpha v) G: cd86 expression in activated macrophages (mus musculus) (aka cd86 expression in activated macrophages) H: icam (rattus norvegicus) (aka intercellular adhesion molecule 1) I: cd51 (homo sapiens) (aka integrin subunit alpha v) J: cd86 (homo sapiens) (aka cd86 molecule) K: cd40l (mus musculus) (aka cd40 ligand) L: cd80 molecule (rattus norvegicus) (aka cd80 molecule) M: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) N: cd80 (homo sapiens) (aka cd80 molecule) O: cd40 antigen (mus musculus) (aka cd40 antigen) P: cd80 (mus musculus) (aka cd80 antigen) Q: cd40 molecule (rattus norvegicus) (aka cd40 molecule) R: icam-1 (mus musculus) (aka intercellular adhesion molecule 1) S: None of the above.
[R; O; P; E]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [intercellular adhesion molecule [icam]-1; cd40; cd80; cd86] <Options>: A: cd86 (mus musculus) (aka cd86 antigen) B: cd80 molecule (rattus norvegicus) (aka cd80 molecule) C: cd40l (mus musculus) (aka cd40 ligand) D: cd80 molecule (homo sapiens) (aka cd80 molecule) E: p50 (homo sapiens) (cd40 molecule (homo sapiens)) (aka cd40 molecule) F: cd86 expression in activated macrophages (mus musculus) (aka cd86 expression in activated macrophages) G: cd51 (homo sapiens) (aka integrin subunit alpha v) H: cd40 molecule (rattus norvegicus) (aka cd40 molecule) I: cd80 (mus musculus) (aka cd80 antigen) J: cd80 (homo sapiens) (aka cd80 molecule) K: cd40l (homo sapiens) (aka cd40 ligand) L: cd86 molecule (rattus norvegicus) (aka cd86 molecule) M: cd86 (homo sapiens) (aka cd86 molecule) N: icam (rattus norvegicus) (aka intercellular adhesion molecule 1) O: cd40 antigen (mus musculus) (aka cd40 antigen) P: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) Q: cd51 (mus musculus) (aka integrin alpha v) R: None of the above.
[R; O; I; A]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [intercellular adhesion molecule [icam]-1; cd40; cd80; cd86] <Options>: A: intercellular adhesion molecule 1 (rattus norvegicus) (aka intercellular adhesion molecule 1) B: cd40l (homo sapiens) (aka cd40 ligand) C: p50 (homo sapiens) (cd40 molecule (homo sapiens)) (aka cd40 molecule) D: cd86 molecule (homo sapiens) (aka cd86 molecule) E: icam-1 (mus musculus) (aka intercellular adhesion molecule 1) F: cd51 (mus musculus) (aka integrin alpha v) G: cd80 (mus musculus) (aka cd80 antigen) H: cd80 antigen (mus musculus) (aka cd80 antigen) I: cd86 (homo sapiens) (aka cd86 molecule) J: cd80 (rattus norvegicus) (aka cd80 molecule) K: cd86 antigen (mus musculus) (aka cd86 antigen) L: cd80 (homo sapiens) (aka cd80 molecule) M: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) N: cd51 (homo sapiens) (aka integrin subunit alpha v) O: cd86 (rattus norvegicus) (aka cd86 molecule) P: cd40l (mus musculus) (aka cd40 ligand) Q: cd40 (rattus norvegicus) (aka cd40 molecule) R: p50 (mus musculus) (cd40 antigen (mus musculus)) (aka cd40 antigen) S: None of the above.
[E; R; H; K]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [intercellular adhesion molecule [icam]-1; cd40; cd80; cd86] <Options>: A: cd80 (rattus norvegicus) (aka cd80 molecule) B: cd80 molecule (homo sapiens) (aka cd80 molecule) C: cd40 (mus musculus) (aka cd40 antigen) D: cd86 (homo sapiens) (aka cd86 molecule) E: cd86 molecule (rattus norvegicus) (aka cd86 molecule) F: cd86 expression in activated macrophages (mus musculus) (aka cd86 expression in activated macrophages) G: b7 (mus musculus) (cd86 antigen (mus musculus)) (aka cd86 antigen) H: cd51 (homo sapiens) (aka integrin subunit alpha v) I: cd40l (mus musculus) (aka cd40 ligand) J: icam (rattus norvegicus) (aka intercellular adhesion molecule 1) K: cd80 antigen (mus musculus) (aka cd80 antigen) L: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) M: icam1 (mus musculus) (aka intercellular adhesion molecule 1) N: cd86 (mus musculus) (aka cd86 antigen) O: cd40l (homo sapiens) (aka cd40 ligand) P: cd80 (mus musculus) (aka cd80 antigen) Q: cd40 (rattus norvegicus) (aka cd40 molecule) R: cd51 (mus musculus) (aka integrin alpha v) S: p50 (homo sapiens) (cd40 molecule (homo sapiens)) (aka cd40 molecule) T: None of the above.
[M; C; K; N]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [intercellular adhesion molecule [icam]-1; cd40; cd80; cd86] <Options>: A: icam (rattus norvegicus) (aka intercellular adhesion molecule 1) B: cd40 (homo sapiens) (aka cd40 molecule) C: cd86 antigen (mus musculus) (aka cd86 antigen) D: cd40l (mus musculus) (aka cd40 ligand) E: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) F: cd86 (rattus norvegicus) (aka cd86 molecule) G: cd40l (homo sapiens) (aka cd40 ligand) H: cd40 (mus musculus) (aka cd40 antigen) I: b7 (mus musculus) (cd86 antigen (mus musculus)) (aka cd86 antigen) J: cd51 (mus musculus) (aka integrin alpha v) K: cd51 (homo sapiens) (aka integrin subunit alpha v) L: cd86 (homo sapiens) (aka cd86 molecule) M: cd80 antigen (mus musculus) (aka cd80 antigen) N: cd40 molecule (rattus norvegicus) (aka cd40 molecule) O: cd80 (rattus norvegicus) (aka cd80 molecule) P: cd80 (homo sapiens) (aka cd80 molecule) Q: intercellular adhesion molecule 1 (mus musculus) (aka intercellular adhesion molecule 1) R: cd80 (mus musculus) (aka cd80 antigen) S: None of the above.
[Q; H; M; C]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr7; ccr2; ccr6] <Options>: A: ccr2 (danio rerio) (aka chemokine (c-c motif) receptor 2) B: c-x-c motif chemokine receptor 6 (mus musculus) (aka c-x-c motif chemokine receptor 6) C: ccr6 (rattus norvegicus) (aka c-c motif chemokine receptor 6) D: c-c motif chemokine receptor 7 (homo sapiens) (aka c-c motif chemokine receptor 7) E: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2) F: ccr-6 (mus musculus) (aka c-c motif chemokine receptor 6) G: c-c motif chemokine receptor 7 (mus musculus) (aka c-c motif chemokine receptor 7) H: cxcr6 (homo sapiens) (aka c-x-c motif chemokine receptor 6) I: ccr5 (mus musculus) (aka c-c motif chemokine receptor 5) J: ccr2b (mus musculus) (aka c-c motif chemokine receptor 2) K: ccr7 (danio rerio) (aka chemokine (c-c motif) receptor 7) L: ccr7 (rattus norvegicus) (aka c-c motif chemokine receptor 7) M: cxcr7 (mus musculus) (aka atypical chemokine receptor 3) N: ccr2 (rattus norvegicus) (aka c-c motif chemokine receptor 2) O: ccr6 (homo sapiens) (aka c-c motif chemokine receptor 6) P: None of the above.
[G; J; F]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr7; ccr2; ccr6] <Options>: A: c-x-c motif chemokine receptor 6 (mus musculus) (aka c-x-c motif chemokine receptor 6) B: ccr2 (rattus norvegicus) (aka c-c motif chemokine receptor 2) C: ccr6 (rattus norvegicus) (aka c-c motif chemokine receptor 6) D: ccr2 (mus musculus) (aka c-c motif chemokine receptor 2) E: c-c motif chemokine receptor 7 (mus musculus) (aka c-c motif chemokine receptor 7) F: c-c motif chemokine receptor 6 (mus musculus) (aka c-c motif chemokine receptor 6) G: ccr5 (homo sapiens) (aka c-c motif chemokine receptor 5) H: ccr2 (danio rerio) (aka chemokine (c-c motif) receptor 2) I: ccr2b (mus musculus) (aka c-c motif chemokine receptor 2) J: c-c motif chemokine receptor 6 (homo sapiens) (aka c-c motif chemokine receptor 6) K: cxcr6 (homo sapiens) (aka c-x-c motif chemokine receptor 6) L: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2) M: cxcr7 (homo sapiens) (aka atypical chemokine receptor 3) N: ccr7 (rattus norvegicus) (aka c-c motif chemokine receptor 7) O: ccr7 (danio rerio) (aka chemokine (c-c motif) receptor 7) P: None of the above.
[E; I; F]
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr7; ccr2; ccr6] <Options>: A: ccr2 (homo sapiens) (aka c-c motif chemokine receptor 2) B: c-c motif chemokine receptor 2 (homo sapiens) (aka c-c motif chemokine receptor 2) C: c-x-c motif chemokine receptor 6 (mus musculus) (aka c-x-c motif chemokine receptor 6) D: ccr7 (danio rerio) (aka chemokine (c-c motif) receptor 7) E: cxcr7 (homo sapiens) (aka atypical chemokine receptor 3) F: cxcr6 (homo sapiens) (aka c-x-c motif chemokine receptor 6) G: c-c motif chemokine receptor 6 (homo sapiens) (aka c-c motif chemokine receptor 6) H: c-c motif chemokine receptor 6 (rattus norvegicus) (aka c-c motif chemokine receptor 6) I: ccr2 (mus musculus) (aka c-c motif chemokine receptor 2) J: ccr7 (mus musculus) (aka c-c motif chemokine receptor 7) K: c-c motif chemokine receptor 6 (mus musculus) (aka c-c motif chemokine receptor 6) L: ccr2 (rattus norvegicus) (aka c-c motif chemokine receptor 2) M: ccr5 (mus musculus) (aka c-c motif chemokine receptor 5) N: ccr5 (homo sapiens) (aka c-c motif chemokine receptor 5) O: None of the above.
[J; I; K]
<Instruct>: Given the context 'In addition, these cells were unable to undergo full phenotypic activation upon in vitro culture in presence of maturation stimuli such as lipopolysaccharide or poly (I:C), which paralleled with lack of Toll-like receptor (TLR)3 mRNA expression.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [toll-like receptor (tlr)3] <Options>: A: toll-like receptor 3 (dermatophagoides pteronyssinus) (aka toll-like receptor 3) B: tlr3 (homo sapiens) (aka toll like receptor 3) C: toll3 (drosophila melanogaster) (aka mstprox) D: toll-like receptor 3 (mus musculus) (aka toll-like receptor 3) E: tlr3 (rattus norvegicus) (aka toll-like receptor 3) F: None of the above.
[D]
<Instruct>: Given the context 'Finally, cytokine expression pattern was also altered in ICSBP(-/-)', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp] <Options>: A: illbp (mus musculus) (aka fatty acid binding protein 6) B: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) C: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) D: ilbp (homo sapiens) (aka fatty acid binding protein 6) E: icsbp (mus musculus) (aka interferon regulatory factor 8) F: None of the above.
[E]
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [interleukin (il)-12p40; il-15; il-4] <Options>: A: il15 (homo sapiens) (aka interleukin 15) B: interleukin 12b (homo sapiens) (aka interleukin 12b) C: interleukin 12a (mus musculus) (aka interleukin 12a) D: il5 (homo sapiens) (aka interleukin 5) E: il-12a (homo sapiens) (aka interleukin 12a) F: il15 (mus musculus) (aka interleukin 15) G: interleukin 15 (cricetulus griseus) (aka interleukin 15) H: il-4 (mus musculus) (aka interleukin 4) I: il-4 (homo sapiens) (aka interleukin 4) J: interleukin 4 (ovis aries) (aka interleukin 4) K: p40 (mus musculus) (interleukin 12b (mus musculus)) (aka interleukin 12b) L: interleukin 4 (rattus norvegicus) (aka interleukin 4) M: interleukin 15 (ovis aries) (aka interleukin 15) N: None of the above.
[K; F; H]
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [interleukin (il)-12p40; il-15; il-4] <Options>: A: interleukin 12a (mus musculus) (aka interleukin 12a) B: il4 (ovis aries) (aka interleukin 4) C: interleukin 4 (rattus norvegicus) (aka interleukin 4) D: interleukin 15 (rattus norvegicus) (aka interleukin 15) E: il4 (homo sapiens) (aka interleukin 4) F: il-12a (homo sapiens) (aka interleukin 12a) G: interleukin 15 (homo sapiens) (aka interleukin 15) H: interleukin 12b (homo sapiens) (aka interleukin 12b) I: il5 (homo sapiens) (aka interleukin 5) J: il12p40 (mus musculus) (aka interleukin 12b) K: interleukin 15 (ovis aries) (aka interleukin 15) L: interleukin 15 (mus musculus) (aka interleukin 15) M: il4 (mus musculus) (aka interleukin 4) N: None of the above.
[J; L; M]
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [interleukin (il)-12p40; il-15; il-4] <Options>: A: il5 (homo sapiens) (aka interleukin 5) B: interleukin 4 (rattus norvegicus) (aka interleukin 4) C: il-15 (mus musculus) (aka interleukin 15) D: interleukin 12a (mus musculus) (aka interleukin 12a) E: interleukin 4 (homo sapiens) (aka interleukin 4) F: il-12p40 (mus musculus) (aka interleukin 12b) G: il-12b (homo sapiens) (aka interleukin 12b) H: il-12a (homo sapiens) (aka interleukin 12a) I: interleukin 4 (mus musculus) (aka interleukin 4) J: il4 (ovis aries) (aka interleukin 4) K: interleukin 15 (rattus norvegicus) (aka interleukin 15) L: interleukin 15 (homo sapiens) (aka interleukin 15) M: interleukin 15 (cricetulus griseus) (aka interleukin 15) N: None of the above.
[F; C; I]
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; cd8alpha] <Options>: A: h-icsbp (homo sapiens) (aka interferon regulatory factor 8) B: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha) C: icsbp1 (rattus norvegicus) (aka interferon regulatory factor 8) D: cd8 (homo sapiens) (aka cd8 subunit alpha) E: ilbp (homo sapiens) (aka fatty acid binding protein 6) F: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) G: cd8b1 (mus musculus) (aka cd8 subunit beta 1) H: illbp (mus musculus) (aka fatty acid binding protein 6) I: cd8a (rattus norvegicus) (aka cd8 subunit alpha) J: icsbp (mus musculus) (aka interferon regulatory factor 8) K: None of the above.
[J; B]
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [icsbp; cd8alpha] <Options>: A: illbp (mus musculus) (aka fatty acid binding protein 6) B: ilbp (homo sapiens) (aka fatty acid binding protein 6) C: cd8a (mus musculus) (aka cd8 subunit alpha) D: icsbp (mus musculus) (aka interferon regulatory factor 8) E: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta) F: cd8 subunit alpha (rattus norvegicus) (aka cd8 subunit alpha) G: icsbp (rattus norvegicus) (aka interferon regulatory factor 8) H: icsbp1 (homo sapiens) (aka interferon regulatory factor 8) I: cd8b1 (mus musculus) (aka cd8 subunit beta 1) J: cd8alpha (homo sapiens) (aka cd8 subunit alpha) K: None of the above.
[D; C]
<Instruct>: Given the context 'Sarco(endo)plasmic reticulum Ca2+-ATPase-2 gene: structure and transcriptional regulation of the human gene.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [sarco(endo)plasmic reticulum ca2+-atpase-2] <Options>: A: atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) B: atpase plasma membrane ca2+ transporting 2 (homo sapiens) (aka atpase plasma membrane ca2+ transporting 2) C: serca2 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) D: atpase, ca++ transporting, plasma membrane 2 (mus musculus) (aka atpase, ca++ transporting, plasma membrane 2) E: atpase secretory pathway ca2+ transporting 2 (rattus norvegicus) (aka atpase secretory pathway ca2+ transporting 2) F: None of the above.
[A]
<Instruct>: Given the context 'The sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) belong to a family of active calcium transport enzymes encoded by the SERCA1, 2, and 3 genes.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [serca1, 2, and 3] <Options>: A: serca2 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) B: atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) C: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3) D: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) E: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1) F: None of the above.
[B]
<Instruct>: Given the context 'In this study, we describe the complete structure of the human SERCA2 gene and its 5 -regulatory region.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [serca2] <Options>: A: atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) B: atp2a (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) C: serca2a (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) D: sercaii (rattus norvegicus) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) E: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b) F: None of the above.
[A]
<Instruct>: Given the context 'The hSERCA2 gene is located in chromosome 12 position q24.1 in Contig NT_009770.8, spans 70 kb, and is organized in 21 exons intervened by 20 introns.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [hserca2] <Options>: A: ces2a (rattus norvegicus) (aka carboxylesterase 2a) B: smarca2 (rattus norvegicus) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2) C: smarca2 (mus musculus) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2) D: ces2a (mus musculus) (aka carboxylesterase 2a) E: repa2 (homo sapiens) (aka replication protein a2) F: None of the above.
[F]
<Instruct>: Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [serca2a; serca2b] <Options>: A: serca2 (rattus norvegicus) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) B: serca3b (mus musculus) (aka atpase, ca++ transporting, ubiquitous) C: serca2a (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) D: atp2a (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) E: sercaii (rattus norvegicus) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) F: atp2b (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) G: atp2a2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) H: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b) I: serca2 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) J: None of the above.
[G; F]
<Instruct>: Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [serca2a; serca2b] <Options>: A: atp2a (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) B: atp2b (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) C: serca2 (rattus norvegicus) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) D: atp2a2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) E: serca3b (mus musculus) (aka atpase, ca++ transporting, ubiquitous) F: serca2a (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) G: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) H: serca2 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) I: None of the above.
[D; B]
<Instruct>: Given the context 'The sequence of the proximal 225-bp regulatory region of the SERCA2 genes is 80% G+C-rich and is conserved among human, rabbit, rat, and mouse species.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [serca2] <Options>: A: atp2a (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) B: serca2 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) C: atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) D: serca2 (rattus norvegicus) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) E: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b) F: None of the above.
[C]
<Instruct>: Given the context 'It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE).', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [sp1] <Options>: A: h-sp1 (homo sapiens) (aka synaptophysin like 1) B: sp1 (rattus norvegicus) (aka sp1 transcription factor) C: sp1 (cricetulus griseus) (aka sp1 transcription factor) D: sp1 (homo sapiens) (sp1 transcription factor (homo sapiens)) (aka sp1 transcription factor) E: sp1 (xenopus laevis) (aka sp1 transcription factor l homeolog) F: None of the above.
[D]
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gata-4, -5, -6; nkx-2.5; csx; otf-1] <Options>: A: otf1 (homo sapiens) (aka pou class 2 homeobox 1) B: csx (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog) C: csx3 (homo sapiens) (aka nk2 homeobox 3) D: scx (homo sapiens) (aka scleraxis bhlh transcription factor) E: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis)) (aka nk2 homeobox 5 s homeolog) F: pou1f1 (homo sapiens) (aka pou class 1 homeobox 1) G: nkx-5.1 (homo sapiens) (aka h6 family homeobox 3) H: nkx-2.3 (mus musculus) (aka nk2 homeobox 3) I: oligodendrocyte transcription factor 1 (mus musculus) (aka oligodendrocyte transcription factor 1) J: csx (mus musculus) (aka nk2 homeobox 5) K: gata5 (mus musculus) (aka gata binding protein 5) L: csx (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis)) (aka nk2 homeobox 5 s homeolog) M: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog) N: gata5 (rattus norvegicus) (aka gata binding protein 5) O: gata-4 (mus musculus) (aka gata binding protein 4) P: gata binding protein 6 (mus musculus) (aka gata binding protein 6) Q: nkx-2.5 (mus musculus) (aka nk2 homeobox 5) R: obf-1 (mus musculus) (aka pou domain, class 2, associating factor 1) S: otf1 (mus musculus) (aka pou domain, class 2, transcription factor 1) T: gata binding protein 6 (rattus norvegicus) (aka gata binding protein 6) U: None of the above.
[T; Q; J; A]
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gata-4, -5, -6; nkx-2.5; csx; otf-1] <Options>: A: oligodendrocyte transcription factor 1 (mus musculus) (aka oligodendrocyte transcription factor 1) B: csx (mus musculus) (aka nk2 homeobox 5) C: gata binding protein 6 (mus musculus) (aka gata binding protein 6) D: scx (homo sapiens) (aka scleraxis bhlh transcription factor) E: otf1 (mus musculus) (aka pou domain, class 2, transcription factor 1) F: nkx-2.3 (mus musculus) (aka nk2 homeobox 3) G: obf-1 (mus musculus) (aka pou domain, class 2, associating factor 1) H: nkx-2.5 (mus musculus) (aka nk2 homeobox 5) I: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis)) (aka nk2 homeobox 5 s homeolog) J: csx (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis)) (aka nk2 homeobox 5 s homeolog) K: csx3 (homo sapiens) (aka nk2 homeobox 3) L: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog) M: gata5 (mus musculus) (aka gata binding protein 5) N: nkx-5.1 (homo sapiens) (aka h6 family homeobox 3) O: gata binding protein 6 (rattus norvegicus) (aka gata binding protein 6) P: csx (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog) Q: gata5 (rattus norvegicus) (aka gata binding protein 5) R: pou1f1 (homo sapiens) (aka pou class 1 homeobox 1) S: gata-4 (mus musculus) (aka gata binding protein 4) T: None of the above.
[O; H; B; T]
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gata-4, -5, -6; nkx-2.5; csx; otf-1] <Options>: A: csx (homo sapiens) (aka nk2 homeobox 5) B: gata5 (mus musculus) (aka gata binding protein 5) C: csx3 (homo sapiens) (aka nk2 homeobox 3) D: nkx-2.5 (mus musculus) (aka nk2 homeobox 5) E: nkx-2.6 (mus musculus) (aka nk2 homeobox 6) F: gata6 (homo sapiens) (aka gata binding protein 6) G: csx (mus musculus) (aka nk2 homeobox 5) H: otf-1 (xenopus laevis) (aka pou class 2 homeobox 1 l homeolog) I: obf-1 (mus musculus) (aka pou domain, class 2, associating factor 1) J: nkx-2.2 (mus musculus) (aka nk2 homeobox 2) K: gata6 (rattus norvegicus) (aka gata binding protein 6) L: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog) M: gata6 (mus musculus) (aka gata binding protein 6) N: scx (cricetulus griseus) (aka scleraxis bhlh transcription factor) O: nkx-5.2 (mus musculus) (aka h6 homeobox 2) P: pou1f1 (homo sapiens) (aka pou class 1 homeobox 1) Q: otf1 (mus musculus) (aka pou domain, class 2, transcription factor 1) R: otf1 (homo sapiens) (aka pou class 2 homeobox 1) S: gata5 (rattus norvegicus) (aka gata binding protein 5) T: scx (homo sapiens) (aka scleraxis bhlh transcription factor) U: None of the above.
[K; D; G; R]
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gata-4, -5, -6; nkx-2.5; csx; otf-1] <Options>: A: pou domain, class 1, transcription factor 1 (mus musculus) (aka pou domain, class 1, transcription factor 1) B: csx (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog) C: otf1 (homo sapiens) (aka pou class 2 homeobox 1) D: csx (rattus norvegicus) (aka nk2 homeobox 5) E: pou1f1 (rattus norvegicus) (aka pou class 1 homeobox 1) F: gata binding protein 6 (mus musculus) (aka gata binding protein 6) G: nkx-2.2 (mus musculus) (aka nk2 homeobox 2) H: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis)) (aka nk2 homeobox 5 s homeolog) I: csx (mus musculus) (aka nk2 homeobox 5) J: gata binding protein 6 (rattus norvegicus) (aka gata binding protein 6) K: nkx-2.3 (mus musculus) (aka nk2 homeobox 3) L: otf-1 (xenopus laevis) (aka pou class 2 homeobox 1 l homeolog) M: scx (homo sapiens) (aka scleraxis bhlh transcription factor) N: nkx-2.5 (mus musculus) (aka nk2 homeobox 5) O: obf-1 (mus musculus) (aka pou domain, class 2, associating factor 1) P: gata-4 (mus musculus) (aka gata binding protein 4) Q: nkx-5.1 (homo sapiens) (aka h6 family homeobox 3) R: gata5 (rattus norvegicus) (aka gata binding protein 5) S: csx2 (homo sapiens) (aka nk2 homeobox 6) T: gata5 (mus musculus) (aka gata binding protein 5) U: None of the above.
[J; N; I; C]
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gata-4, -5, -6; nkx-2.5; csx; otf-1] <Options>: A: csx (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog) B: otf1 (homo sapiens) (aka pou class 2 homeobox 1) C: gata6 (rattus norvegicus) (aka gata binding protein 6) D: nkx-5.1 (mus musculus) (aka h6 homeobox 3) E: otf-1 (xenopus laevis) (aka pou class 2 homeobox 1 l homeolog) F: pou domain, class 1, transcription factor 1 (mus musculus) (aka pou domain, class 1, transcription factor 1) G: gata6 (homo sapiens) (aka gata binding protein 6) H: pou1f1 (rattus norvegicus) (aka pou class 1 homeobox 1) I: nkx-2.5 (mus musculus) (aka nk2 homeobox 5) J: nkx-2.6 (mus musculus) (aka nk2 homeobox 6) K: csx2 (homo sapiens) (aka nk2 homeobox 6) L: csx (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis)) (aka nk2 homeobox 5 s homeolog) M: nkx-1.2 (mus musculus) (aka nk1 homeobox 2) N: csx (mus musculus) (aka nk2 homeobox 5) O: csx3 (homo sapiens) (aka nk2 homeobox 3) P: gata-6 (mus musculus) (aka gata binding protein 6) Q: otf1 (mus musculus) (aka pou domain, class 2, transcription factor 1) R: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis)) (aka nk2 homeobox 5 s homeolog) S: gata5 (rattus norvegicus) (aka gata binding protein 5) T: gata-4 (mus musculus) (aka gata binding protein 4) U: None of the above.
[C; I; N; B]
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [srf; ap-2] <Options>: A: transcription factor ap-2 (drosophila melanogaster) (aka transcription factor ap-2) B: srf (xenopus laevis) (aka serum response factor l homeolog) C: transcription factor ap-2 alpha (rattus norvegicus) (aka transcription factor ap-2 alpha) D: srf (danio rerio) (aka serum response factor a) E: srf (rattus norvegicus) (aka serum response factor) F: srf1 (homo sapiens) (aka spermatogenesis associated 6) G: ap-2 (mus musculus) (aka transcription factor ap-2, alpha) H: ap-2(beta) (mus musculus) (aka transcription factor ap-2 beta) I: srf (homo sapiens) (aka serum response factor) J: transcription factor ap-2 alpha (homo sapiens) (aka transcription factor ap-2 alpha) K: None of the above.
[I; J]
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [srf; ap-2] <Options>: A: transcription factor ap-2 alpha (rattus norvegicus) (aka transcription factor ap-2 alpha) B: serum response factor (homo sapiens) (aka serum response factor) C: transcription factor ap-2 alpha (homo sapiens) (aka transcription factor ap-2 alpha) D: ap-2(beta) (mus musculus) (aka transcription factor ap-2 beta) E: transcription factor ap-2 (drosophila melanogaster) (aka transcription factor ap-2) F: srf (xenopus laevis) (aka serum response factor l homeolog) G: transcription factor ap-2, alpha (mus musculus) (aka transcription factor ap-2, alpha) H: srf1 (homo sapiens) (aka spermatogenesis associated 6) I: serum response factor (mus musculus) (aka serum response factor) J: srf (danio rerio) (aka serum response factor a) K: None of the above.
[B; C]
<Instruct>: Given the context 'Upstream from position -1.5 kb, there is no significant homology among the SERCA2 genes cloned.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [serca2] <Options>: A: sercaii (rattus norvegicus) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) B: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b) C: serca2b (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) D: atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) E: atp2a (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) F: None of the above.
[D]
<Instruct>: Given the context 'In this study, we report the cloning of 2.4 kb of 5-regulatory region and demonstrate that the proximal promoter region is sufficient for expression in cardiac myocytes, and the region from -225 to -1232 bp contains regulatory DNA elements which down-regulate the expression of the SERCA2 gene in neonatal cardiomyocytes.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [serca2] <Options>: A: serca2 (rattus norvegicus) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) B: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b) C: serca2b (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2) D: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2) E: atp2a (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1) F: None of the above.
[D]
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [nfkappab; rage; receptor for advanced glycation end products] <Options>: A: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit) B: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) C: rage (rattus norvegicus) (mok protein kinase (rattus norvegicus)) (aka mok protein kinase) D: nf-kappab (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells 1, p105) E: p65 nf-kappa b (mus musculus) (aka v-rel reticuloendotheliosis viral oncogene homolog a (avian)) F: advanced glycosylation end-product specific receptor (homo sapiens) (aka advanced glycosylation end-product specific receptor) G: rage-1 (homo sapiens) (aka mok protein kinase) H: nfkb (rattus norvegicus) (aka rela proto-oncogene, nf-kb subunit) I: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) J: rage1 (mus musculus) (aka mok protein kinase) K: advanced glycosylation end product-specific receptor (rattus norvegicus) (aka advanced glycosylation end product-specific receptor) L: nuclear factor kappa b subunit 1 (homo sapiens) (aka nuclear factor kappa b subunit 1) M: rage1 (homo sapiens) (aka mok protein kinase) N: None of the above.
[L; B; F]
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [nfkappab; rage; receptor for advanced glycation end products] <Options>: A: rage (mus musculus) (mok protein kinase (mus musculus)) (aka mok protein kinase) B: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) C: advanced glycosylation end product-specific receptor (mus musculus) (aka advanced glycosylation end product-specific receptor) D: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) E: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit) F: p65 nf-kappa b (mus musculus) (aka v-rel reticuloendotheliosis viral oncogene homolog a (avian)) G: rage1 (homo sapiens) (aka mok protein kinase) H: rage1 (mus musculus) (aka mok protein kinase) I: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor) J: nfkb (rattus norvegicus) (aka rela proto-oncogene, nf-kb subunit) K: ager (homo sapiens) (aka advanced glycosylation end-product specific receptor) L: nfkappab (homo sapiens) (aka nuclear factor kappa b subunit 1) M: nf-kappab (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells 1, p105) N: rage (rattus norvegicus) (mok protein kinase (rattus norvegicus)) (aka mok protein kinase) O: None of the above.
[L; B; K]
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [nfkappab; rage; receptor for advanced glycation end products] <Options>: A: nf-kappab (homo sapiens) (aka nuclear factor kappa b subunit 1) B: rage1 (mus musculus) (aka mok protein kinase) C: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit) D: rage (rattus norvegicus) (mok protein kinase (rattus norvegicus)) (aka mok protein kinase) E: rage1 (homo sapiens) (aka mok protein kinase) F: nf-kappab (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells 1, p105) G: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor) H: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) I: nfkb (rattus norvegicus) (aka rela proto-oncogene, nf-kb subunit) J: ager (homo sapiens) (aka advanced glycosylation end-product specific receptor) K: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) L: p65 nfkb (mus musculus) (aka v-rel reticuloendotheliosis viral oncogene homolog a (avian)) M: ager (mus musculus) (aka advanced glycosylation end product-specific receptor) N: None of the above.
[A; H; J]
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [rage; s100a8; s100a9] <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9) B: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8) C: gfr (homo sapiens) (aka rap guanine nucleotide exchange factor 5) D: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) E: s100a8 (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) F: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) G: rage1 (mus musculus) (aka mok protein kinase) H: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) I: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) J: rage (rattus norvegicus) (mok protein kinase (rattus norvegicus)) (aka mok protein kinase) K: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) L: None of the above.
[I; B; A]
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [rage; s100a8; s100a9] <Options>: A: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) B: gfr (homo sapiens) (aka rap guanine nucleotide exchange factor 5) C: rage1 (mus musculus) (aka mok protein kinase) D: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) E: s100a9 (homo sapiens) (aka s100 calcium binding protein a9) F: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) G: rage (rattus norvegicus) (mok protein kinase (rattus norvegicus)) (aka mok protein kinase) H: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) I: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) J: s100a8 (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) K: None of the above.
[D; K; E]
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [rage; s100a8; s100a9] <Options>: A: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) B: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) C: rage (rattus norvegicus) (mok protein kinase (rattus norvegicus)) (aka mok protein kinase) D: p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8) E: s100-a9 (homo sapiens) (aka s100 calcium binding protein a9) F: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) G: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor) H: gfr (homo sapiens) (aka rap guanine nucleotide exchange factor 5) I: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) J: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) K: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) L: None of the above.
[F; D; E]
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [rage; s100a8; s100a9] <Options>: A: rage (homo sapiens) (mok protein kinase (homo sapiens)) (aka mok protein kinase) B: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) C: s100a8 (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) D: gfr (homo sapiens) (aka rap guanine nucleotide exchange factor 5) E: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) F: s100-a9 (homo sapiens) (aka s100 calcium binding protein a9) G: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor) H: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) I: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) J: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8) K: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) L: None of the above.
[I; J; F]
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [nfkappab] <Options>: A: nf-kappab (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells 1, p105) B: nfkb (rattus norvegicus) (aka rela proto-oncogene, nf-kb subunit) C: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit) D: nfkappab (homo sapiens) (aka nuclear factor kappa b subunit 1) E: p65 nfkb (mus musculus) (aka v-rel reticuloendotheliosis viral oncogene homolog a (avian)) F: None of the above.
[D]
<Instruct>: Given the context 'Human umbilical vein endothelial cells (HUVEC) were preincubated for 72 h with AGE-albumin or unmodified albumin for control, whereas AGE-albumin induction resulted in an upregulation of RAGE.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [rage] <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor) B: gfr (homo sapiens) (aka rap guanine nucleotide exchange factor 5) C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor) D: rage (rattus norvegicus) (mok protein kinase (rattus norvegicus)) (aka mok protein kinase) E: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor) F: None of the above.
[C]
<Instruct>: Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9] <Options>: A: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) B: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) C: s100-a8 (homo sapiens) (aka s100 calcium binding protein a8) D: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) E: mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) F: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) G: None of the above.
[C; E]
<Instruct>: Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9] <Options>: A: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) B: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) C: s100-a8 (homo sapiens) (aka s100 calcium binding protein a8) D: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) E: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) F: None of the above.
[C; F]
<Instruct>: Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9] <Options>: A: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) B: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) C: p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) D: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) E: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) F: s100a8 (homo sapiens) (aka s100 calcium binding protein a8) G: None of the above.
[F; C]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; il-6; icam-1] <Options>: A: cd51 (mus musculus) (aka integrin alpha v) B: s100a8 (homo sapiens) (aka s100 calcium binding protein a8) C: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) D: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9) E: cd51 (homo sapiens) (aka integrin subunit alpha v) F: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) G: il6 (mus musculus) (aka interleukin 6) H: il-6 (homo sapiens) (aka interleukin 6) I: interleukin 6 (ovis aries) (aka interleukin 6) J: vcam1 (homo sapiens) (aka vascular cell adhesion molecule 1) K: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) L: nf-il6 (mus musculus) (aka ccaat/enhancer binding protein beta) M: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) N: icam1 (mus musculus) (aka intercellular adhesion molecule 1) O: il6 (rattus norvegicus) (aka interleukin 6) P: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) Q: None of the above.
[B; D; H; P]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; il-6; icam-1] <Options>: A: nf-il6 (mus musculus) (aka ccaat/enhancer binding protein beta) B: vcam-1 (mus musculus) (aka vascular cell adhesion molecule 1) C: icam1 (homo sapiens) (aka intercellular adhesion molecule 1) D: icam1 (rattus norvegicus) (aka intercellular adhesion molecule 1) E: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) F: il6 (rattus norvegicus) (aka interleukin 6) G: cd51 (homo sapiens) (aka integrin subunit alpha v) H: il6 (mus musculus) (aka interleukin 6) I: interleukin 6 (ovis aries) (aka interleukin 6) J: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) K: il-6 (homo sapiens) (aka interleukin 6) L: icam1 (mus musculus) (aka intercellular adhesion molecule 1) M: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) N: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8) O: p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) P: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) Q: None of the above.
[N; O; K; C]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; il-6; icam-1] <Options>: A: icam1 (mus musculus) (aka intercellular adhesion molecule 1) B: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) C: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) D: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) E: cd51 (homo sapiens) (aka integrin subunit alpha v) F: il6 (rattus norvegicus) (aka interleukin 6) G: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8) H: p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) I: il6 (mus musculus) (aka interleukin 6) J: il-6 (homo sapiens) (aka interleukin 6) K: interleukin 6 (ovis aries) (aka interleukin 6) L: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) M: nf-il6 (mus musculus) (aka ccaat/enhancer binding protein beta) N: icam1 (rattus norvegicus) (aka intercellular adhesion molecule 1) O: vcam-1 (mus musculus) (aka vascular cell adhesion molecule 1) P: None of the above.
[G; H; J; P]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; il-6; icam-1] <Options>: A: cd51 (mus musculus) (aka integrin alpha v) B: s100 calcium binding protein a9 (calgranulin b) (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) C: icam1 (rattus norvegicus) (aka intercellular adhesion molecule 1) D: il6 (homo sapiens) (aka interleukin 6) E: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) F: vcam-1 (mus musculus) (aka vascular cell adhesion molecule 1) G: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) H: p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) I: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) J: il6 (mus musculus) (aka interleukin 6) K: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) L: cd51 (homo sapiens) (aka integrin subunit alpha v) M: nf-il6 (mus musculus) (aka ccaat/enhancer binding protein beta) N: interleukin 6 (ovis aries) (aka interleukin 6) O: s100a8 (homo sapiens) (aka s100 calcium binding protein a8) P: interleukin 6 (rattus norvegicus) (aka interleukin 6) Q: None of the above.
[O; H; D; I]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; il-6; icam-1] <Options>: A: vcam1 (homo sapiens) (aka vascular cell adhesion molecule 1) B: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) C: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) D: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1) E: icam1 (rattus norvegicus) (aka intercellular adhesion molecule 1) F: s100-a9 (homo sapiens) (aka s100 calcium binding protein a9) G: nf-il6 (mus musculus) (aka ccaat/enhancer binding protein beta) H: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) I: il-6 (mus musculus) (aka interleukin 6) J: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8) K: interleukin 6 (ovis aries) (aka interleukin 6) L: s100a8 (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) M: il6 (homo sapiens) (aka interleukin 6) N: il6 (rattus norvegicus) (aka interleukin 6) O: cd51 (mus musculus) (aka integrin alpha v) P: vcam-1 (mus musculus) (aka vascular cell adhesion molecule 1) Q: None of the above.
[J; F; M; D]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [vcam-1; mcp1] <Options>: A: mcp1 (ovis aries) (aka mast cell proteinase-1) B: icam-1 (mus musculus) (aka intercellular adhesion molecule 1) C: vcam-1 (mus musculus) (aka vascular cell adhesion molecule 1) D: platelet/endothelial cell adhesion molecule 1 (mus musculus) (aka platelet/endothelial cell adhesion molecule 1) E: mcp-1 (mus musculus) (c-c motif chemokine ligand 2 (mus musculus)) (aka c-c motif chemokine ligand 2) F: vascular cell adhesion molecule 1 (homo sapiens) (aka vascular cell adhesion molecule 1) G: ccl1 (homo sapiens) (aka c-c motif chemokine ligand 1) H: mcp1 (homo sapiens) (aka c-c motif chemokine ligand 2) I: ccl1 (mus musculus) (aka c-c motif chemokine ligand 1) J: vcam-1 (ovis aries) (aka vascular cell adhesion protein 1) K: None of the above.
[F; H]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [vcam-1; mcp1] <Options>: A: platelet/endothelial cell adhesion molecule 1 (mus musculus) (aka platelet/endothelial cell adhesion molecule 1) B: vcam-1 (ovis aries) (aka vascular cell adhesion protein 1) C: ccl1 (homo sapiens) (aka c-c motif chemokine ligand 1) D: mcp-1 (mus musculus) (c-c motif chemokine ligand 2 (mus musculus)) (aka c-c motif chemokine ligand 2) E: icam-1 (mus musculus) (aka intercellular adhesion molecule 1) F: mcp1 (homo sapiens) (aka c-c motif chemokine ligand 2) G: vcam-1 (mus musculus) (aka vascular cell adhesion molecule 1) H: ccl1 (mus musculus) (aka c-c motif chemokine ligand 1) I: mcp1 (ovis aries) (aka mast cell proteinase-1) J: None of the above.
[J; F]
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [vcam-1; mcp1] <Options>: A: vcam-1 (mus musculus) (aka vascular cell adhesion molecule 1) B: mcp-1 (mus musculus) (c-c motif chemokine ligand 2 (mus musculus)) (aka c-c motif chemokine ligand 2) C: mcp-1 (homo sapiens) (aka c-c motif chemokine ligand 2) D: vcam1 (rattus norvegicus) (aka vascular cell adhesion molecule 1) E: vcam-1 (ovis aries) (aka vascular cell adhesion protein 1) F: platelet/endothelial cell adhesion molecule 1 (mus musculus) (aka platelet/endothelial cell adhesion molecule 1) G: mcp1 (saccharomyces cerevisiae s288c) (aka mcp1p) H: ccl1 (homo sapiens) (aka c-c motif chemokine ligand 1) I: vascular cell adhesion molecule 1 (homo sapiens) (aka vascular cell adhesion molecule 1) J: ccl1 (mus musculus) (aka c-c motif chemokine ligand 1) K: None of the above.
[I; C]
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; s100a1; s100b] <Options>: A: s100 protein, beta polypeptide, neural (mus musculus) (aka s100 protein, beta polypeptide, neural) B: cal (mus musculus) (s100 calcium binding protein a11 (mus musculus)) (aka s100 calcium binding protein a11) C: s100a1 (rattus norvegicus) (s100 calcium binding protein a1 (rattus norvegicus)) (aka s100 calcium binding protein a1) D: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) E: s100a8 (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) F: s100a11 (homo sapiens) (aka s100 calcium binding protein a11) G: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8) H: s100 calcium binding protein a1 (mus musculus) (aka s100 calcium binding protein a1) I: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9) J: s100b (rattus norvegicus) (aka s100 calcium binding protein b) K: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) L: s100a (homo sapiens) (aka s100 calcium binding protein a1) M: s100 calcium binding protein b (homo sapiens) (aka s100 calcium binding protein b) N: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) O: s100 (mus musculus) (aka s100 calcium binding protein a1) P: None of the above.
[G; I; L; M]
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; s100a1; s100b] <Options>: A: cal (mus musculus) (s100 calcium binding protein a11 (mus musculus)) (aka s100 calcium binding protein a11) B: s100 protein, beta polypeptide, neural (mus musculus) (aka s100 protein, beta polypeptide, neural) C: s100 calcium binding protein a1 (mus musculus) (aka s100 calcium binding protein a1) D: s100a1 (homo sapiens) (aka s100 calcium binding protein a1) E: s100b (rattus norvegicus) (aka s100 calcium binding protein b) F: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) G: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) H: s100a1 (rattus norvegicus) (s100 calcium binding protein a1 (rattus norvegicus)) (aka s100 calcium binding protein a1) I: s100 (mus musculus) (aka s100 calcium binding protein a1) J: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) K: mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8) L: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) M: p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) N: s100beta (homo sapiens) (aka s100 calcium binding protein b) O: s100a11 (homo sapiens) (aka s100 calcium binding protein a11) P: None of the above.
[K; M; D; N]
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; s100a1; s100b] <Options>: A: s100beta (homo sapiens) (aka s100 calcium binding protein b) B: cal (mus musculus) (s100 calcium binding protein a11 (mus musculus)) (aka s100 calcium binding protein a11) C: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) D: s100 protein, beta polypeptide, neural (mus musculus) (aka s100 protein, beta polypeptide, neural) E: mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8) F: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) G: s100a1 (rattus norvegicus) (s100 calcium binding protein a1 (rattus norvegicus)) (aka s100 calcium binding protein a1) H: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) I: s100 calcium binding protein a1 (mus musculus) (aka s100 calcium binding protein a1) J: s100a11 (homo sapiens) (aka s100 calcium binding protein a11) K: s100a1 (homo sapiens) (aka s100 calcium binding protein a1) L: s100 (mus musculus) (aka s100 calcium binding protein a1) M: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) N: s100b (rattus norvegicus) (aka s100 calcium binding protein b) O: None of the above.
[E; O; K; A]
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; s100a1; s100b] <Options>: A: s100a (mus musculus) (aka s100 calcium binding protein a1) B: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) C: s100a1 (rattus norvegicus) (s100 calcium binding protein a1 (rattus norvegicus)) (aka s100 calcium binding protein a1) D: s100-b (homo sapiens) (aka s100 calcium binding protein b) E: cal (mus musculus) (s100 calcium binding protein a11 (mus musculus)) (aka s100 calcium binding protein a11) F: s100b (mus musculus) (aka s100 protein, beta polypeptide, neural) G: s100a9 (homo sapiens) (aka s100 calcium binding protein a9) H: s100a11 (homo sapiens) (aka s100 calcium binding protein a11) I: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) J: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) K: s100 (mus musculus) (aka s100 calcium binding protein a1) L: s100 (homo sapiens) (s100 calcium binding protein a1 (homo sapiens)) (aka s100 calcium binding protein a1) M: s100 calcium binding protein b (rattus norvegicus) (aka s100 calcium binding protein b) N: s100a8 (homo sapiens) (aka s100 calcium binding protein a8) O: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) P: None of the above.
[N; G; L; D]
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; s100a1; s100b] <Options>: A: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) B: s100 calcium binding protein b (homo sapiens) (aka s100 calcium binding protein b) C: s100a1 (rattus norvegicus) (s100 calcium binding protein a1 (rattus norvegicus)) (aka s100 calcium binding protein a1) D: s100a (mus musculus) (aka s100 calcium binding protein a1) E: s100b (rattus norvegicus) (aka s100 calcium binding protein b) F: s100 protein, beta polypeptide, neural (mus musculus) (aka s100 protein, beta polypeptide, neural) G: s100a11 (homo sapiens) (aka s100 calcium binding protein a11) H: s100a8 (homo sapiens) (aka s100 calcium binding protein a8) I: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) J: s100 (mus musculus) (aka s100 calcium binding protein a1) K: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9) L: s100a (homo sapiens) (aka s100 calcium binding protein a1) M: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) N: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) O: cal (mus musculus) (s100 calcium binding protein a11 (mus musculus)) (aka s100 calcium binding protein a11) P: None of the above.
[H; K; L; B]
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; p38] <Options>: A: mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8) B: p38mapk (mus musculus) (aka mitogen-activated protein kinase 14) C: p38 (homo sapiens) (mitogen-activated protein kinase 1 (homo sapiens)) (aka mitogen-activated protein kinase 1) D: mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) E: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) F: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) G: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) H: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) I: p38 (rattus norvegicus) (aka mitogen activated protein kinase 14) J: p38 (homo sapiens) (mitogen-activated protein kinase 14 (homo sapiens)) (aka mitogen-activated protein kinase 14) K: None of the above.
[A; D; J]
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; p38] <Options>: A: p38a (mus musculus) (aka mitogen-activated protein kinase 14) B: p38 (rattus norvegicus) (aka mitogen activated protein kinase 14) C: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) D: p38 (homo sapiens) (mitogen-activated protein kinase 1 (homo sapiens)) (aka mitogen-activated protein kinase 1) E: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) F: p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8) G: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) H: p38alpha (homo sapiens) (aka mitogen-activated protein kinase 14) I: s100-a9 (homo sapiens) (aka s100 calcium binding protein a9) J: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) K: None of the above.
[F; I; H]
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9; p38] <Options>: A: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) B: s100a8 (homo sapiens) (aka s100 calcium binding protein a8) C: s100 calcium binding protein a9 (calgranulin b) (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) D: p38alpha (rattus norvegicus) (aka mitogen activated protein kinase 14) E: mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens)) (aka s100 calcium binding protein a9) F: p38 (homo sapiens) (mitogen-activated protein kinase 14 (homo sapiens)) (aka mitogen-activated protein kinase 14) G: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) H: p38 (homo sapiens) (mitogen-activated protein kinase 1 (homo sapiens)) (aka mitogen-activated protein kinase 1) I: p38-alpha (mus musculus) (aka mitogen-activated protein kinase 14) J: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) K: None of the above.
[B; E; F]
<Instruct>: Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9] <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9) B: p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8) C: s100 calcium binding protein a8 (rattus norvegicus) (aka s100 calcium binding protein a8) D: s100a8 (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) E: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) F: p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus)) (aka s100 calcium binding protein a9 (calgranulin b)) G: None of the above.
[B; A]
<Instruct>: Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9] <Options>: A: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) B: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) C: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9) D: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8) E: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) F: s100 calcium binding protein a8 (calgranulin a) (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) G: None of the above.
[D; C]
<Instruct>: Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9] <Options>: A: s100-a8 (homo sapiens) (aka s100 calcium binding protein a8) B: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) C: s100a9 (homo sapiens) (aka s100 calcium binding protein a9) D: s100 calcium binding protein a9 (rattus norvegicus) (aka s100 calcium binding protein a9) E: s100a9 (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) F: p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus)) (aka s100 calcium binding protein a8 (calgranulin a)) G: None of the above.
[A; C]
<Instruct>: Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [s100a8; s100a9] <Options>: A: s100a8 (rattus norvegicus) (aka s100 calcium binding protein a8) B: s100 calcium binding protein a9 (calgranulin b) (mus musculus) (aka s100 calcium binding protein a9 (calgranulin b)) C: p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8) D: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9) E: s100a9 (rattus norvegicus) (aka s100 calcium binding protein a9) F: s100a8 (mus musculus) (aka s100 calcium binding protein a8 (calgranulin a)) G: None of the above.
[C; D]
<Instruct>: Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [growth hormone; gh1] <Options>: A: gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus)) (aka growth hormone 1) B: gh (mus musculus) (aka growth hormone) C: growth hormone (ovis aries) (aka growth hormone) D: gh1 (homo sapiens) (aka growth hormone 1) E: gh1b1 (mus musculus) (aka growth hormone) F: gh1 (ovis aries) (aka growth hormone) G: gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus)) (aka gonadotropin releasing hormone receptor) H: growth hormone 1 (rattus norvegicus) (aka growth hormone 1) I: growth hormone 1 (homo sapiens) (aka growth hormone 1) J: growth hormone 2 (homo sapiens) (aka growth hormone 2) K: None of the above.
[D; I]
<Instruct>: Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [growth hormone; gh1] <Options>: A: gh (mus musculus) (aka growth hormone) B: gh (rattus norvegicus) (aka growth hormone 1) C: gh1 (cricetulus griseus) (aka growth hormone 1) D: gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus)) (aka gonadotropin releasing hormone receptor) E: growth hormone 2 (homo sapiens) (aka growth hormone 2) F: gh1 (danio rerio) (aka growth hormone 1) G: growth hormone (ovis aries) (aka growth hormone) H: gh1 (homo sapiens) (aka growth hormone 1) I: None of the above.
[H; H]
<Instruct>: Given the context 'OBJECTIVE: GH1 gene presents a complex map of single nucleotide polymorphisms (SNPs) in the entire promoter, coding and noncoding regions.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gh1] <Options>: A: gh (mus musculus) (aka growth hormone) B: growth hormone 1 (homo sapiens) (aka growth hormone 1) C: gh1 (danio rerio) (aka growth hormone 1) D: gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus)) (aka gonadotropin releasing hormone receptor) E: gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus)) (aka growth hormone 1) F: None of the above.
[B]
<Instruct>: Given the context 'OBJECTIVE: GH1 gene presents a complex map of single nucleotide polymorphisms (SNPs) in the entire promoter, coding and noncoding regions.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gh1] <Options>: A: gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus)) (aka growth hormone 1) B: gh1 (danio rerio) (aka growth hormone 1) C: gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus)) (aka gonadotropin releasing hormone receptor) D: gh (mus musculus) (aka growth hormone) E: None of the above.
[E]
<Instruct>: Given the context 'The aim of the study was to establish the complete map of GH1 gene SNPs in our control normal population and to analyse its association with adult height.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gh1] <Options>: A: gh1 (ovis aries) (aka growth hormone) B: gh1 (danio rerio) (aka growth hormone 1) C: gh1 (cricetulus griseus) (aka growth hormone 1) D: gh (homo sapiens) (growth hormone 1 (homo sapiens)) (aka growth hormone 1) E: gh (mus musculus) (aka growth hormone) F: None of the above.
[D]
<Instruct>: Given the context 'DESIGN, SUBJECTS AND MEASUREMENTS: A systematic GH1 gene analysis was designed in a control population of 307 adults of both sexes with height normally distributed within normal range for the same population: -2 standard deviation scores (SDS) to +2 SDS.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gh1] <Options>: A: gh1 (danio rerio) (aka growth hormone 1) B: gh1 (cricetulus griseus) (aka growth hormone 1) C: gh (homo sapiens) (growth hormone 1 (homo sapiens)) (aka growth hormone 1) D: gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus)) (aka growth hormone 1) E: gh1 (ovis aries) (aka growth hormone) F: None of the above.
[C]
<Instruct>: Given the context 'This study established the GH1 gene sequence variation map in a normal adult height control population confirming the high density of SNPs in a relatively small gene.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gh1] <Options>: A: gh1 (ovis aries) (aka growth hormone) B: growth hormone 1 (homo sapiens) (aka growth hormone 1) C: gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus)) (aka gonadotropin releasing hormone receptor) D: gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus)) (aka growth hormone 1) E: gh (mus musculus) (aka growth hormone) F: None of the above.
[B]
<Instruct>: Given the context 'Systematic GH1 gene analysis in patients with growth delay and suspected GH deficiency/insufficiency will clarify whether different SNP frequencies and/or the presence of different sequence changes may be associated with phenotypes in them.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [gh1] <Options>: A: growth hormone 1 (homo sapiens) (aka growth hormone 1) B: gh1 (cricetulus griseus) (aka growth hormone 1) C: gh1 (ovis aries) (aka growth hormone) D: gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus)) (aka growth hormone 1) E: gh (mus musculus) (aka growth hormone) F: None of the above.
[A]
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr2; ccr5; cox1; cox2] <Options>: A: cox (homo sapiens) (cytochrome c oxidase subunit 5a (homo sapiens)) (aka cytochrome c oxidase subunit 5a) B: ccr2 (homo sapiens) (aka c-c motif chemokine receptor 2) C: cox2 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 2) D: ccr5 (homo sapiens) (aka c-c motif chemokine receptor 5) E: cox2 (rattus norvegicus) (cytochrome c oxidase ii, mitochondrial (rattus norvegicus)) (aka cytochrome c oxidase ii, mitochondrial) F: cox1 (homo sapiens) (mitochondrially encoded cytochrome c oxidase i (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase i) G: cox1 (rattus norvegicus) (cytochrome c oxidase i, mitochondrial (rattus norvegicus)) (aka cytochrome c oxidase i, mitochondrial) H: ccr2 (danio rerio) (aka chemokine (c-c motif) receptor 2) I: c-c motif chemokine receptor 2 (mus musculus) (aka c-c motif chemokine receptor 2) J: ccr5 (mus musculus) (aka c-c motif chemokine receptor 5) K: cox2 (homo sapiens) (mitochondrially encoded cytochrome c oxidase ii (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase ii) L: cox-1 (mus musculus) (aka prostaglandin-endoperoxide synthase 1) M: c-c motif chemokine receptor 5 (rattus norvegicus) (aka c-c motif chemokine receptor 5) N: cox-2 (mus musculus) (aka prostaglandin-endoperoxide synthase 2) O: cox1 (homo sapiens) (prostaglandin-endoperoxide synthase 1 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 1) P: ccr2 (mus musculus) (aka c-c motif chemokine receptor 2) Q: cox2 (homo sapiens) (prostaglandin-endoperoxide synthase 2 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 2) R: None of the above.
[B; D; O; Q]
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr2; ccr5; cox1; cox2] <Options>: A: cox-2 (rattus norvegicus) (aka prostaglandin-endoperoxide synthase 2) B: cox1 (homo sapiens) (prostaglandin-endoperoxide synthase 1 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 1) C: cox1 (caenorhabditis elegans) (aka cytochrome c oxidase subunit i) D: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2) E: cox2 (mus musculus) (cytochrome c oxidase ii, mitochondrial (mus musculus)) (aka cytochrome c oxidase ii, mitochondrial) F: cox2 (homo sapiens) (prostaglandin-endoperoxide synthase 2 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 2) G: cox2 (rattus norvegicus) (cytochrome c oxidase ii, mitochondrial (rattus norvegicus)) (aka cytochrome c oxidase ii, mitochondrial) H: ccr2 (danio rerio) (aka chemokine (c-c motif) receptor 2) I: cox1 (homo sapiens) (mitochondrially encoded cytochrome c oxidase i (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase i) J: ccr5 (ovis aries) (aka c-c motif chemokine receptor 5) K: cox1 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 1) L: ccr5 (homo sapiens) (aka c-c motif chemokine receptor 5) M: ccr5 (rattus norvegicus) (aka c-c motif chemokine receptor 5) N: cox2 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 2) O: ccr2 (homo sapiens) (aka c-c motif chemokine receptor 2) P: cox (homo sapiens) (cytochrome c oxidase subunit 5a (homo sapiens)) (aka cytochrome c oxidase subunit 5a) Q: ccr5 (mus musculus) (aka c-c motif chemokine receptor 5) R: ccr2 (rattus norvegicus) (aka c-c motif chemokine receptor 2) S: None of the above.
[D; L; B; F]
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr2; ccr5; cox1; cox2] <Options>: A: c-c motif chemokine receptor 5 (homo sapiens) (aka c-c motif chemokine receptor 5) B: cox (homo sapiens) (cytochrome c oxidase subunit 5a (homo sapiens)) (aka cytochrome c oxidase subunit 5a) C: ccr5 (homo sapiens) (aka c-c motif chemokine receptor 5) D: cox1 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 1) E: cox2 (homo sapiens) (prostaglandin-endoperoxide synthase 2 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 2) F: cox1 (homo sapiens) (prostaglandin-endoperoxide synthase 1 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 1) G: cox1 (mus musculus) (cytochrome c oxidase i, mitochondrial (mus musculus)) (aka cytochrome c oxidase i, mitochondrial) H: ccr5 (ovis aries) (aka c-c motif chemokine receptor 5) I: ccr5 (mus musculus) (aka c-c motif chemokine receptor 5) J: ccr2 (danio rerio) (aka chemokine (c-c motif) receptor 2) K: cox-2 (mus musculus) (aka prostaglandin-endoperoxide synthase 2) L: cox2 (rattus norvegicus) (prostaglandin-endoperoxide synthase 2 (rattus norvegicus)) (aka prostaglandin-endoperoxide synthase 2) M: cox2 (homo sapiens) (mitochondrially encoded cytochrome c oxidase ii (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase ii) N: ccr5 (rattus norvegicus) (aka c-c motif chemokine receptor 5) O: ccr2 (rattus norvegicus) (aka c-c motif chemokine receptor 2) P: ccr2 (homo sapiens) (aka c-c motif chemokine receptor 2) Q: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2) R: c-c motif chemokine receptor 5 (mus musculus) (aka c-c motif chemokine receptor 5) S: cox1 (homo sapiens) (mitochondrially encoded cytochrome c oxidase i (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase i) T: cox2 (mus musculus) (cytochrome c oxidase ii, mitochondrial (mus musculus)) (aka cytochrome c oxidase ii, mitochondrial) U: None of the above.
[Q; A; F; E]
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr2; ccr5; cox1; cox2] <Options>: A: cox2 (homo sapiens) (mitochondrially encoded cytochrome c oxidase ii (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase ii) B: cox2 (rattus norvegicus) (cytochrome c oxidase ii, mitochondrial (rattus norvegicus)) (aka cytochrome c oxidase ii, mitochondrial) C: ccr2 (danio rerio) (aka chemokine (c-c motif) receptor 2) D: ccr5 (homo sapiens) (aka c-c motif chemokine receptor 5) E: cox2 (rattus norvegicus) (prostaglandin-endoperoxide synthase 2 (rattus norvegicus)) (aka prostaglandin-endoperoxide synthase 2) F: cox1 (rattus norvegicus) (cytochrome c oxidase i, mitochondrial (rattus norvegicus)) (aka cytochrome c oxidase i, mitochondrial) G: cox1 (homo sapiens) (prostaglandin-endoperoxide synthase 1 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 1) H: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2) I: c-c motif chemokine receptor 5 (homo sapiens) (aka c-c motif chemokine receptor 5) J: ccr5 (rattus norvegicus) (aka c-c motif chemokine receptor 5) K: ccr2 (rattus norvegicus) (aka c-c motif chemokine receptor 2) L: ccr5 (mus musculus) (aka c-c motif chemokine receptor 5) M: cox2 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 2) N: cox (homo sapiens) (cytochrome c oxidase subunit 5a (homo sapiens)) (aka cytochrome c oxidase subunit 5a) O: cox1 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 1) P: cox1 (rattus norvegicus) (prostaglandin-endoperoxide synthase 1 (rattus norvegicus)) (aka prostaglandin-endoperoxide synthase 1) Q: ccr5 (ovis aries) (aka c-c motif chemokine receptor 5) R: cox-2 (homo sapiens) (prostaglandin-endoperoxide synthase 2 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 2) S: None of the above.
[H; I; G; R]
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [ccr2; ccr5; cox1; cox2] <Options>: A: ccr5 (ovis aries) (aka c-c motif chemokine receptor 5) B: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2) C: ccr5 (rattus norvegicus) (aka c-c motif chemokine receptor 5) D: cox2 (rattus norvegicus) (cytochrome c oxidase ii, mitochondrial (rattus norvegicus)) (aka cytochrome c oxidase ii, mitochondrial) E: ccr2 (danio rerio) (aka chemokine (c-c motif) receptor 2) F: cox2 (homo sapiens) (mitochondrially encoded cytochrome c oxidase ii (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase ii) G: ccr5 (homo sapiens) (aka c-c motif chemokine receptor 5) H: cox2 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 2) I: cox (homo sapiens) (cytochrome c oxidase subunit 5a (homo sapiens)) (aka cytochrome c oxidase subunit 5a) J: cox1 (rattus norvegicus) (prostaglandin-endoperoxide synthase 1 (rattus norvegicus)) (aka prostaglandin-endoperoxide synthase 1) K: cox1 (saccharomyces cerevisiae s288c) (aka cytochrome c oxidase subunit 1) L: ccr5 (mus musculus) (aka c-c motif chemokine receptor 5) M: cox1 (rattus norvegicus) (cytochrome c oxidase i, mitochondrial (rattus norvegicus)) (aka cytochrome c oxidase i, mitochondrial) N: cox-2 (homo sapiens) (prostaglandin-endoperoxide synthase 2 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 2) O: cox2 (rattus norvegicus) (prostaglandin-endoperoxide synthase 2 (rattus norvegicus)) (aka prostaglandin-endoperoxide synthase 2) P: ccr2 (rattus norvegicus) (aka c-c motif chemokine receptor 2) Q: c-c motif chemokine receptor 5 (homo sapiens) (aka c-c motif chemokine receptor 5) R: None of the above.
[B; Q; R; N]
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [crp; csf1; csf2; ifng] <Options>: A: colony stimulating factor 1 (rattus norvegicus) (aka colony stimulating factor 1) B: crp1 (mus musculus) (ccaat/enhancer binding protein epsilon (mus musculus)) (aka ccaat/enhancer binding protein epsilon) C: csf2 (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage)) D: colony stimulating factor 2 (ovis aries) (aka colony stimulating factor 2) E: csf-1 (homo sapiens) (aka colony stimulating factor 1) F: ifngm (homo sapiens) (aka interferon production regulator) G: colony stimulating factor 2 (rattus norvegicus) (aka colony stimulating factor 2) H: ifng (cricetulus griseus) (aka interferon gamma) I: crp (mus musculus) (cysteine rich protein 2 (mus musculus)) (aka cysteine rich protein 2) J: sdf1 (homo sapiens) (aka c-x-c motif chemokine ligand 12) K: csf1 (ovis aries) (aka colony stimulating factor 1) L: csf2 (homo sapiens) (aka colony stimulating factor 2) M: crp (homo sapiens) (c-reactive protein (homo sapiens)) (aka c-reactive protein) N: ifng (rattus norvegicus) (aka interferon gamma) O: csf2 (cricetulus griseus) (aka colony stimulating factor 2) P: ifn (homo sapiens) (aka interferon alpha 1) Q: csf1 (saccharomyces cerevisiae s288c) (aka csf1p) R: crp (rattus norvegicus) (c-reactive protein (rattus norvegicus)) (aka c-reactive protein) S: interferon gamma (homo sapiens) (aka interferon gamma) T: crp1 (homo sapiens) (ccaat enhancer binding protein epsilon (homo sapiens)) (aka ccaat enhancer binding protein epsilon) U: None of the above.
[M; E; L; S]
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept for each mention using the provided options. In the answer, list the correct options, one for each mention, separated by semicolon.
<Mentions>: [crp; csf1; csf2; ifng] <Options>: A: crp (homo sapiens) (c-reactive protein (homo sapiens)) (aka c-reactive protein) B: csf2 (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage)) C: crp (homo sapiens) (cysteine and glycine rich protein 1 (homo sapiens)) (aka cysteine and glycine rich protein 1) D: crp (arabidopsis thaliana) (aka rna polymerase ii transcription mediator) E: csf2 (homo sapiens) (aka colony stimulating factor 2) F: crp (mus musculus) (cysteine rich protein 2 (mus musculus)) (aka cysteine rich protein 2) G: ifng (ovis aries) (aka interferon gamma) H: csf1 (homo sapiens) (aka colony stimulating factor 1) I: csf2 (rattus norvegicus) (aka colony stimulating factor 2) J: csf1 (saccharomyces cerevisiae s288c) (aka csf1p) K: crp (rattus norvegicus) (c-reactive protein (rattus norvegicus)) (aka c-reactive protein) L: colony stimulating factor 2 (ovis aries) (aka colony stimulating factor 2) M: ifng (mus musculus) (aka interferon gamma) N: ifng2 (rattus norvegicus) (aka interferon gamma) O: csf1 (ovis aries) (aka colony stimulating factor 1) P: ifn (homo sapiens) (aka interferon alpha 1) Q: sdf1 (homo sapiens) (aka c-x-c motif chemokine ligand 12) R: csf1 (mus musculus) (aka colony stimulating factor 1 (macrophage)) S: ifng (homo sapiens) (aka interferon gamma) T: csf2 (cricetulus griseus) (aka colony stimulating factor 2) U: None of the above.
[A; H; E; S]
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