Dash00/nlm-gene-reranking · Datasets at Hugging Face

query stringlengths 53 153	positive listlengths 1 7	negative listlengths 3 9	system stringlengths 50 956
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', answer the user's query.
What is the biomedical concept corresponding to 'type i interferon'?	[ "ifnb1 (mus musculus)" ]	[ "ifn (homo sapiens)", "interferon alpha 1 (mus musculus)", "ifn1@ (homo sapiens)", "ifna (mus musculus)", "ifnb1 (homo sapiens)", "interferon, alpha 1 (rattus norvegicus)", "ifng (homo sapiens)", "interferon, type 1, cluster (homo sapiens)", "interferon alpha 1 (homo sapiens)" ]	Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', answer the user's query.
What is the biomedical concept corresponding to 'cd8alpha'?	[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]	[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]	Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', answer the user's query.
What is the biomedical concept corresponding to 'interferon (ifn) consensus sequence-binding protein'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "icsbp1 (rattus norvegicus)", "h-icsbp (homo sapiens)", "cold inducible rna binding protein (mus musculus)", "sine oculis binding protein (mus musculus)", "ns1bp (homo sapiens)" ]	Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'In this study, we have characterized the phenotype and activation pattern of subsets of dendritic cells (DCs) in ICSBP(-/-) mice.', answer the user's query.
What is the biomedical concept corresponding to 'ifn'?	[ "ifng (mus musculus)" ]	[ "ifn (homo sapiens)", "ifng (homo sapiens)", "ifn-alpha (homo sapiens)", "ifna (mus musculus)", "ifna@ (homo sapiens)", "ifna (homo sapiens) (interferon, type 1, cluster (homo sapiens))", "ifnaa (mus musculus)", "ifn1@ (homo sapiens)", "interferon kappa (homo sapiens)" ]	Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.
What is the biomedical concept corresponding to 'cd11c'?	[ "cd11c (mus musculus)" ]	[ "cd11c (homo sapiens)", "cd11b (mus musculus)", "cd103 (mus musculus)", "cd11b (homo sapiens)", "cd14 (mus musculus)", "cd103 (homo sapiens)", "cd1 (homo sapiens) (cd1a molecule (homo sapiens))", "cd64 (mus musculus)", "cd1 (mus musculus) (cd1 antigen complex (mus musculus))" ]	Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.
What is the biomedical concept corresponding to 'b220'?	[ "b220 (mus musculus)", "cd45 (mus musculus)", "cd45r (mus musculus)" ]	[ "b220 (homo sapiens)", "cd45 (homo sapiens)", "cd45r (homo sapiens)", "cd79a (mus musculus)", "cd79a (homo sapiens)", "cd20 (mus musculus)", "cd79a antigen (immunoglobulin-associated alpha) (mus musculus)" ]	Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.
What is the biomedical concept corresponding to 'ly6c'?	[ "ly6c (mus musculus)", "ly6c1 (mus musculus)" ]	[ "ly6c (rattus norvegicus)", "ly6-c antigen (rattus norvegicus)", "cd1c molecule (homo sapiens)", "cd1c (homo sapiens)", "ly6 (mus musculus)", "ly6g (mus musculus)", "ly67 (mus musculus)", "ly-c (mus musculus)" ]	Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.
What is the biomedical concept corresponding to 'cd11b'?	[ "cd11b (mus musculus)", "cd11b/cd18 (mus musculus)", "mac1 (mus musculus)" ]	[ "cd11b (homo sapiens)", "cd11b (rattus norvegicus)", "cd11b (danio rerio)", "mac-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens))", "cd61 (mus musculus)", "cd61 (homo sapiens)", "cd11b (ovis aries)" ]	Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.
What is the biomedical concept corresponding to 'cd11c'?	[ "cd11c (mus musculus)" ]	[ "cd11c (homo sapiens)", "cd11b (mus musculus)", "cd103 (mus musculus)", "cd11b (homo sapiens)", "cd14 (mus musculus)", "cd103 (homo sapiens)", "cd1 (homo sapiens) (cd1a molecule (homo sapiens))", "cd64 (mus musculus)", "cd1 (mus musculus) (cd1 antigen complex (mus musculus))" ]	Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', answer the user's query.
What is the biomedical concept corresponding to 'type i ifns'?	[ "ifnb1 (mus musculus)" ]	[ "ifn (homo sapiens)", "ifng (homo sapiens)", "ifna (mus musculus)", "stat1 (homo sapiens)", "ifnb1 (homo sapiens)", "ifng (mus musculus)", "stat1 (mus musculus)", "ifn1@ (homo sapiens)", "interferon, type 1, cluster (homo sapiens)" ]	Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', answer the user's query.
What is the biomedical concept corresponding to 'cd8alpha'?	[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]	[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]	Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', answer the user's query.
What is the biomedical concept corresponding to 'cd8alpha'?	[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]	[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]	Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', answer the user's query.
What is the biomedical concept corresponding to 'cd8alpha'?	[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]	[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]	Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', answer the user's query.
What is the biomedical concept corresponding to 'intercellular adhesion molecule [icam]-1'?	[ "icam1 (mus musculus)", "icam-1 (mus musculus)", "intercellular adhesion molecule 1 (mus musculus)" ]	[ "icam1 (homo sapiens)", "intercellular adhesion molecule 1 (homo sapiens)", "icam1 (rattus norvegicus)", "cd51 (homo sapiens)", "cd51 (mus musculus)", "intercellular adhesion molecule 1 (rattus norvegicus)", "icam (rattus norvegicus)" ]	Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.
What is the biomedical concept corresponding to 'cd40'?	[ "cd40 (mus musculus)", "cd40 antigen (mus musculus)", "p50 (mus musculus) (cd40 antigen (mus musculus))" ]	[ "cd40 (homo sapiens)", "cd40 molecule (homo sapiens)", "p50 (homo sapiens) (cd40 molecule (homo sapiens))", "cd40 (rattus norvegicus)", "cd40 molecule (rattus norvegicus)", "cd40l (homo sapiens)", "cd40l (mus musculus)" ]	Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.
What is the biomedical concept corresponding to 'cd80'?	[ "cd80 (mus musculus)", "cd80 antigen (mus musculus)" ]	[ "cd80 (homo sapiens)", "cd80 molecule (homo sapiens)", "cd80 (rattus norvegicus)", "cd80 molecule (rattus norvegicus)", "cd86 (mus musculus)", "cd86 (homo sapiens)", "b7 (mus musculus) (cd86 antigen (mus musculus))", "cd86 antigen (mus musculus)" ]	Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.
What is the biomedical concept corresponding to 'cd86'?	[ "cd86 (mus musculus)", "cd86 antigen (mus musculus)", "b7 (mus musculus) (cd86 antigen (mus musculus))" ]	[ "cd86 (homo sapiens)", "cd86 molecule (homo sapiens)", "cd86 (rattus norvegicus)", "cd86 molecule (rattus norvegicus)", "cd86 expression in activated macrophages (mus musculus)", "cd80 (mus musculus)", "cd80 (homo sapiens)" ]	Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.
What is the biomedical concept corresponding to 'ccr7'?	[ "ccr7 (mus musculus)", "c-c motif chemokine receptor 7 (mus musculus)" ]	[ "ccr7 (homo sapiens)", "ccr7 (rattus norvegicus)", "ccr7 (danio rerio)", "c-c motif chemokine receptor 7 (homo sapiens)", "ccr2 (homo sapiens)", "ccr2 (mus musculus)", "cxcr7 (homo sapiens)", "cxcr7 (mus musculus)" ]	Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.
What is the biomedical concept corresponding to 'ccr2'?	[ "ccr2 (mus musculus)", "ccr2b (mus musculus)", "c-c motif chemokine receptor 2 (mus musculus)" ]	[ "ccr2 (homo sapiens)", "ccr2 (rattus norvegicus)", "ccr2b (homo sapiens)", "ccr5 (homo sapiens)", "ccr5 (mus musculus)", "c-c motif chemokine receptor 2 (homo sapiens)", "ccr2 (danio rerio)" ]	Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.
What is the biomedical concept corresponding to 'ccr6'?	[ "ccr6 (mus musculus)", "ccr-6 (mus musculus)", "c-c motif chemokine receptor 6 (mus musculus)" ]	[ "ccr6 (homo sapiens)", "ccr-6 (homo sapiens)", "ccr6 (rattus norvegicus)", "c-c motif chemokine receptor 6 (homo sapiens)", "c-c motif chemokine receptor 6 (rattus norvegicus)", "c-x-c motif chemokine receptor 6 (mus musculus)", "cxcr6 (homo sapiens)" ]	Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.
What is the biomedical concept corresponding to 'toll-like receptor (tlr)3'?	[ "toll-like receptor 3 (mus musculus)", "tlr3 (mus musculus)" ]	[ "toll like receptor 3 (homo sapiens)", "toll-like receptor 3 (rattus norvegicus)", "tlr3 (homo sapiens)", "toll-3 (drosophila melanogaster)", "toll3 (drosophila melanogaster)", "tlr3 (rattus norvegicus)", "toll-like receptor 3 (danio rerio)", "toll-like receptor 3 (dermatophagoides pteronyssinus)" ]	Given the context 'In addition, these cells were unable to undergo full phenotypic activation upon in vitro culture in presence of maturation stimuli such as lipopolysaccharide or poly (I:C), which paralleled with lack of Toll-like receptor (TLR)3 mRNA expression.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'Finally, cytokine expression pattern was also altered in ICSBP(-/-)', answer the user's query.
What is the biomedical concept corresponding to 'interleukin (il)-12p40'?	[ "il-12p40 (mus musculus)", "p40 (mus musculus) (interleukin 12b (mus musculus))", "il12p40 (mus musculus)", "interleukin 12b (mus musculus)", "il-12b (mus musculus)" ]	[ "interleukin 12b (homo sapiens)", "il-12b (homo sapiens)", "interleukin 12a (mus musculus)", "interleukin 12a (homo sapiens)", "il-12a (homo sapiens)" ]	Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', answer the user's query.
What is the biomedical concept corresponding to 'il-15'?	[ "interleukin 15 (mus musculus)", "il-15 (mus musculus)", "il15 (mus musculus)" ]	[ "interleukin 15 (homo sapiens)", "il-15 (homo sapiens)", "interleukin 15 (rattus norvegicus)", "il15 (homo sapiens)", "interleukin 15 (ovis aries)", "il5 (homo sapiens)", "interleukin 15 (cricetulus griseus)" ]	Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', answer the user's query.
What is the biomedical concept corresponding to 'il-4'?	[ "interleukin 4 (mus musculus)", "il-4 (mus musculus)", "il4 (mus musculus)" ]	[ "interleukin 4 (homo sapiens)", "il-4 (homo sapiens)", "il4 (homo sapiens)", "interleukin 4 (rattus norvegicus)", "interleukin 4 (ovis aries)", "il-4 (ovis aries)", "il4 (ovis aries)" ]	Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.
What is the biomedical concept corresponding to 'cd8alpha'?	[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]	[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]	Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.
What is the biomedical concept corresponding to 'icsbp'?	[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]	[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]	Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.
What is the biomedical concept corresponding to 'sarco(endo)plasmic reticulum ca2+-atpase-2'?	[ "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "serca2 (homo sapiens)", "atp2a2 (homo sapiens)" ]	[ "atpase plasma membrane ca2+ transporting 2 (homo sapiens)", "atpase secretory pathway ca2+ transporting 2 (homo sapiens)", "serca2 (mus musculus)", "serca2 (rattus norvegicus)", "atpase, ca++ transporting, plasma membrane 2 (mus musculus)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (rattus norvegicus)", "atpase secretory pathway ca2+ transporting 2 (rattus norvegicus)" ]	Given the context 'Sarco(endo)plasmic reticulum Ca2+-ATPase-2 gene: structure and transcriptional regulation of the human gene.', answer the user's query.
What is the biomedical concept corresponding to 'serca1, 2, and 3'?	[ "serca1 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1 (homo sapiens)" ]	[ "serca1 (mus musculus)", "serca3 (homo sapiens)", "serca1 (rattus norvegicus)", "serca3 (mus musculus)", "serca2 (homo sapiens)", "serca3 (rattus norvegicus)", "serca2 (mus musculus)", "serca2a (mus musculus)" ]	Given the context 'The sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) belong to a family of active calcium transport enzymes encoded by the SERCA1, 2, and 3 genes.', answer the user's query.
What is the biomedical concept corresponding to 'serca2'?	[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]	[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]	Given the context 'In this study, we describe the complete structure of the human SERCA2 gene and its 5 -regulatory region.', answer the user's query.
What is the biomedical concept corresponding to 'serca2a'?	[ "serca2 (homo sapiens)", "atp2a2 (homo sapiens)" ]	[ "serca2a (mus musculus)", "serca2 (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "atp2a (homo sapiens)", "sercaii (rattus norvegicus)", "atp2a1 (homo sapiens)", "serca1 (homo sapiens)" ]	Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', answer the user's query.
What is the biomedical concept corresponding to 'serca2b'?	[ "serca2 (homo sapiens)", "atp2b (homo sapiens)" ]	[ "serca2b (mus musculus)", "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "sercaii (rattus norvegicus)", "serca3b (mus musculus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]	Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', answer the user's query.
What is the biomedical concept corresponding to 'serca2'?	[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]	[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]	Given the context 'The sequence of the proximal 225-bp regulatory region of the SERCA2 genes is 80% G+C-rich and is conserved among human, rabbit, rat, and mouse species.', answer the user's query.
What is the biomedical concept corresponding to 'sp1'?	[ "sp1 transcription factor (homo sapiens)", "sp1 (homo sapiens) (sp1 transcription factor (homo sapiens))" ]	[ "sp1 (mus musculus)", "sp1 (arabidopsis thaliana)", "sp1 transcription factor (rattus norvegicus)", "sp1 (rattus norvegicus)", "sp1 (xenopus laevis)", "h-sp1 (homo sapiens)", "sp1 (danio rerio)", "sp1 (cricetulus griseus)" ]	Given the context 'It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE).', answer the user's query.
What is the biomedical concept corresponding to 'gata-4, -5, -6'?	[ "gata6 (rattus norvegicus)", "gata binding protein 6 (rattus norvegicus)" ]	[ "gata-6 (mus musculus)", "gata6 (mus musculus)", "gata6 (homo sapiens)", "gata-4 (mus musculus)", "gata binding protein 6 (homo sapiens)", "gata5 (rattus norvegicus)", "gata5 (mus musculus)", "gata binding protein 6 (mus musculus)" ]	Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.
What is the biomedical concept corresponding to 'nkx-2.5'?	[ "nkx-2.5 (mus musculus)" ]	[ "nkx-5.2 (mus musculus)", "nkx-2.3 (mus musculus)", "nkx-5.1 (mus musculus)", "nkx-2.2 (mus musculus)", "nkx-5.1 (homo sapiens)", "nkx-2.5 (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis))", "nkx-1.2 (mus musculus)", "nkx-2.5 (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis))", "nkx-2.6 (mus musculus)" ]	Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.
What is the biomedical concept corresponding to 'csx'?	[ "csx (mus musculus)" ]	[ "csx (homo sapiens)", "csx (rattus norvegicus)", "csx1 (homo sapiens)", "csx (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis))", "csx (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis))", "csx3 (homo sapiens)", "scx (homo sapiens)", "scx (cricetulus griseus)", "csx2 (homo sapiens)" ]	Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.
What is the biomedical concept corresponding to 'otf-1'?	[ "otf1 (homo sapiens)" ]	[ "otf-1 (mus musculus)", "otf1 (mus musculus)", "otf-1 (xenopus laevis)", "obf-1 (mus musculus)", "pou1f1 (mus musculus)", "pou domain, class 1, transcription factor 1 (mus musculus)", "oligodendrocyte transcription factor 1 (mus musculus)", "pou1f1 (rattus norvegicus)", "pou1f1 (homo sapiens)" ]	Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.
What is the biomedical concept corresponding to 'srf'?	[ "srf (homo sapiens)", "serum response factor (homo sapiens)" ]	[ "srf (mus musculus)", "srf (rattus norvegicus)", "srf1 (homo sapiens)", "srf (xenopus laevis)", "serum response factor (mus musculus)", "srf (danio rerio)", "srf-1 (homo sapiens)", "serum response factor (rattus norvegicus)" ]	Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.
What is the biomedical concept corresponding to 'ap-2'?	[ "ap-2 (homo sapiens)", "transcription factor ap-2 alpha (homo sapiens)" ]	[ "ap-2 (mus musculus)", "transcription factor ap-2 (drosophila melanogaster)", "ap2 (mus musculus) (transcription factor ap-2, alpha (mus musculus))", "ap-2 (drosophila melanogaster) (transcription factor ap-2 (drosophila melanogaster))", "transcription factor ap-2, alpha (mus musculus)", "ap-2 (a) (mus musculus)", "ap-2(beta) (mus musculus)", "transcription factor ap-2 alpha (rattus norvegicus)" ]	Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.
What is the biomedical concept corresponding to 'serca2'?	[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]	[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]	Given the context 'Upstream from position -1.5 kb, there is no significant homology among the SERCA2 genes cloned.', answer the user's query.
What is the biomedical concept corresponding to 'serca2'?	[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]	[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]	Given the context 'In this study, we report the cloning of 2.4 kb of 5-regulatory region and demonstrate that the proximal promoter region is sufficient for expression in cardiac myocytes, and the region from -225 to -1232 bp contains regulatory DNA elements which down-regulate the expression of the SERCA2 gene in neonatal cardiomyocytes.', answer the user's query.
What is the biomedical concept corresponding to 'nfkappab'?	[ "nfkappab (homo sapiens)", "nf-kappab (homo sapiens)", "nf-kappabeta (homo sapiens)", "nf-kb (homo sapiens)", "nuclear factor kappa b subunit 1 (homo sapiens)" ]	[ "nf-kappab (mus musculus)", "nfkb (rattus norvegicus)", "p65 nf-kappa b (mus musculus)", "p65 nfkb (mus musculus)", "rela proto-oncogene, nf-kb subunit (homo sapiens)" ]	Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', answer the user's query.
What is the biomedical concept corresponding to 'rage'?	[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]	[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]	Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', answer the user's query.
What is the biomedical concept corresponding to 'receptor for advanced glycation end products'?	[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))", "advanced glycosylation end-product specific receptor (homo sapiens)", "ager (homo sapiens)" ]	[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "advanced glycosylation end product-specific receptor (mus musculus)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "ager (mus musculus)", "advanced glycosylation end product-specific receptor (rattus norvegicus)", "rage1 (homo sapiens)", "rage1 (mus musculus)" ]	Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', answer the user's query.
What is the biomedical concept corresponding to 'rage'?	[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]	[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]	Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.
What is the biomedical concept corresponding to 's100a8'?	[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]	[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]	Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.
What is the biomedical concept corresponding to 's100a9'?	[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]	[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]	Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.
What is the biomedical concept corresponding to 'rage'?	[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]	[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]	Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.
What is the biomedical concept corresponding to 'nfkappab'?	[ "nfkappab (homo sapiens)", "nf-kappab (homo sapiens)", "nf-kappabeta (homo sapiens)", "nf-kb (homo sapiens)", "nuclear factor kappa b subunit 1 (homo sapiens)" ]	[ "nf-kappab (mus musculus)", "nfkb (rattus norvegicus)", "p65 nf-kappa b (mus musculus)", "p65 nfkb (mus musculus)", "rela proto-oncogene, nf-kb subunit (homo sapiens)" ]	Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.
What is the biomedical concept corresponding to 'rage'?	[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]	[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]	Given the context 'Human umbilical vein endothelial cells (HUVEC) were preincubated for 72 h with AGE-albumin or unmodified albumin for control, whereas AGE-albumin induction resulted in an upregulation of RAGE.', answer the user's query.
What is the biomedical concept corresponding to 's100a8'?	[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]	[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]	Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', answer the user's query.
What is the biomedical concept corresponding to 's100a9'?	[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]	[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]	Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', answer the user's query.
What is the biomedical concept corresponding to 's100a8'?	[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]	[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]	Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.
What is the biomedical concept corresponding to 's100a9'?	[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]	[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]	Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.
What is the biomedical concept corresponding to 'il-6'?	[ "interleukin 6 (homo sapiens)", "il-6 (homo sapiens)", "il6 (homo sapiens)" ]	[ "interleukin 6 (mus musculus)", "il-6 (mus musculus)", "interleukin 6 (rattus norvegicus)", "il6 (mus musculus)", "il6 (rattus norvegicus)", "interleukin 6 (ovis aries)", "nf-il6 (mus musculus)" ]	Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.
What is the biomedical concept corresponding to 'icam-1'?	[ "icam1 (homo sapiens)", "intercellular adhesion molecule 1 (homo sapiens)" ]	[ "icam1 (mus musculus)", "icam-1 (mus musculus)", "intercellular adhesion molecule 1 (mus musculus)", "icam1 (rattus norvegicus)", "cd51 (homo sapiens)", "vcam-1 (mus musculus)", "cd51 (mus musculus)", "vcam1 (homo sapiens)" ]	Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.
What is the biomedical concept corresponding to 'vcam-1'?	[ "vcam1 (homo sapiens)", "vascular cell adhesion molecule 1 (homo sapiens)" ]	[ "vcam1 (mus musculus)", "vcam-1 (mus musculus)", "vcam1 (rattus norvegicus)", "vascular cell adhesion molecule 1 (mus musculus)", "vcam-1 (ovis aries)", "platelet/endothelial cell adhesion molecule 1 (mus musculus)", "platelet and endothelial cell adhesion molecule 1 (homo sapiens)", "icam-1 (mus musculus)" ]	Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.
What is the biomedical concept corresponding to 'mcp1'?	[ "mcp1 (homo sapiens)", "mcp-1 (homo sapiens)" ]	[ "mcp1 (mus musculus)", "mcp-1 (mus musculus) (c-c motif chemokine ligand 2 (mus musculus))", "ccl1 (homo sapiens)", "mcp-1 (mus musculus) (mast cell protease 1 (mus musculus))", "mcp-1 (rattus norvegicus)", "ccl1 (mus musculus)", "mcp1 (saccharomyces cerevisiae s288c)", "mcp1 (ovis aries)" ]	Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.
What is the biomedical concept corresponding to 's100a8'?	[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]	[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]	Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.
What is the biomedical concept corresponding to 's100a9'?	[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]	[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]	Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.
What is the biomedical concept corresponding to 's100a1'?	[ "s100a1 (homo sapiens)", "s100a (homo sapiens)", "s100 calcium binding protein a1 (homo sapiens)", "s100 (homo sapiens) (s100 calcium binding protein a1 (homo sapiens))" ]	[ "s100a1 (mus musculus)", "s100a1 (rattus norvegicus) (s100 calcium binding protein a1 (rattus norvegicus))", "s100 calcium binding protein a1 (mus musculus)", "cal (mus musculus) (s100 calcium binding protein a11 (mus musculus))", "s100a (mus musculus)", "s100a11 (homo sapiens)" ]	Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.
What is the biomedical concept corresponding to 's100b'?	[ "s100b (homo sapiens)", "s100-b (homo sapiens)", "s100beta (homo sapiens)", "s100 (homo sapiens) (s100 calcium binding protein b (homo sapiens))", "s100 calcium binding protein b (homo sapiens)" ]	[ "s100b (mus musculus)", "s100b (rattus norvegicus)", "s100 protein, beta polypeptide, neural (mus musculus)", "s100 calcium binding protein b (rattus norvegicus)", "s100 (mus musculus)" ]	Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.
What is the biomedical concept corresponding to 's100a8'?	[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]	[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]	Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', answer the user's query.
What is the biomedical concept corresponding to 's100a9'?	[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]	[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]	Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', answer the user's query.
What is the biomedical concept corresponding to 'p38'?	[ "p38alpha (homo sapiens)", "p38 (homo sapiens) (mitogen-activated protein kinase 14 (homo sapiens))" ]	[ "p38alpha (mus musculus)", "p38 (homo sapiens) (mitogen-activated protein kinase 1 (homo sapiens))", "p38 (rattus norvegicus)", "p38 (mus musculus) (mitogen-activated protein kinase 14 (mus musculus))", "p38a (mus musculus)", "p38alpha (rattus norvegicus)", "p38-alpha (mus musculus)", "p38mapk (mus musculus)" ]	Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', answer the user's query.
What is the biomedical concept corresponding to 's100a8'?	[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]	[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]	Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', answer the user's query.
What is the biomedical concept corresponding to 's100a9'?	[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]	[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]	Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', answer the user's query.
What is the biomedical concept corresponding to 's100a8'?	[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]	[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]	Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', answer the user's query.
What is the biomedical concept corresponding to 's100a9'?	[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]	[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]	Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', answer the user's query.
What is the biomedical concept corresponding to 'growth hormone'?	[ "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)", "gh1 (homo sapiens)" ]	[ "growth hormone (mus musculus)", "gh (mus musculus)", "gh (rattus norvegicus)", "growth hormone 1 (rattus norvegicus)", "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "growth hormone 2 (homo sapiens)", "growth hormone (ovis aries)" ]	Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', answer the user's query.
What is the biomedical concept corresponding to 'gh1'?	[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]	[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]	Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', answer the user's query.
What is the biomedical concept corresponding to 'gh1'?	[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]	[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]	Given the context 'OBJECTIVE: GH1 gene presents a complex map of single nucleotide polymorphisms (SNPs) in the entire promoter, coding and noncoding regions.', answer the user's query.
What is the biomedical concept corresponding to 'gh1'?	[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]	[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]	Given the context 'The aim of the study was to establish the complete map of GH1 gene SNPs in our control normal population and to analyse its association with adult height.', answer the user's query.
What is the biomedical concept corresponding to 'gh1'?	[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]	[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]	Given the context 'DESIGN, SUBJECTS AND MEASUREMENTS: A systematic GH1 gene analysis was designed in a control population of 307 adults of both sexes with height normally distributed within normal range for the same population: -2 standard deviation scores (SDS) to +2 SDS.', answer the user's query.
What is the biomedical concept corresponding to 'gh1'?	[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]	[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]	Given the context 'This study established the GH1 gene sequence variation map in a normal adult height control population confirming the high density of SNPs in a relatively small gene.', answer the user's query.
What is the biomedical concept corresponding to 'gh1'?	[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]	[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]	Given the context 'Systematic GH1 gene analysis in patients with growth delay and suspected GH deficiency/insufficiency will clarify whether different SNP frequencies and/or the presence of different sequence changes may be associated with phenotypes in them.', answer the user's query.
What is the biomedical concept corresponding to 'ccr2'?	[ "ccr2 (homo sapiens)", "ccr2b (homo sapiens)", "c-c motif chemokine receptor 2 (homo sapiens)" ]	[ "ccr2 (mus musculus)", "ccr2 (rattus norvegicus)", "ccr2b (mus musculus)", "ccr5 (homo sapiens)", "c-c motif chemokine receptor 2 (mus musculus)", "ccr5 (mus musculus)", "ccr2 (danio rerio)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'ccr5'?	[ "ccr5 (homo sapiens)", "c-c motif chemokine receptor 5 (homo sapiens)" ]	[ "ccr5 (mus musculus)", "ccr5 (rattus norvegicus)", "ccr2 (mus musculus)", "ccr2 (homo sapiens)", "ccr5 (ovis aries)", "ccr2 (rattus norvegicus)", "c-c motif chemokine receptor 5 (mus musculus)", "c-c motif chemokine receptor 5 (rattus norvegicus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'cox1'?	[ "cox1 (homo sapiens) (prostaglandin-endoperoxide synthase 1 (homo sapiens))" ]	[ "cox1 (homo sapiens) (mitochondrially encoded cytochrome c oxidase i (homo sapiens))", "cox1 (mus musculus) (prostaglandin-endoperoxide synthase 1 (mus musculus))", "cox1 (mus musculus) (cytochrome c oxidase i, mitochondrial (mus musculus))", "cox1 (saccharomyces cerevisiae s288c)", "cox1 (rattus norvegicus) (prostaglandin-endoperoxide synthase 1 (rattus norvegicus))", "cox-1 (mus musculus)", "cox1 (rattus norvegicus) (cytochrome c oxidase i, mitochondrial (rattus norvegicus))", "cox1 (caenorhabditis elegans)", "cox (homo sapiens) (cytochrome c oxidase subunit 5a (homo sapiens))" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'cox2'?	[ "cox2 (homo sapiens) (prostaglandin-endoperoxide synthase 2 (homo sapiens))", "cox-2 (homo sapiens) (prostaglandin-endoperoxide synthase 2 (homo sapiens))" ]	[ "cox2 (mus musculus) (prostaglandin-endoperoxide synthase 2 (mus musculus))", "cox2 (homo sapiens) (mitochondrially encoded cytochrome c oxidase ii (homo sapiens))", "cox2 (mus musculus) (cytochrome c oxidase ii, mitochondrial (mus musculus))", "cox2 (rattus norvegicus) (prostaglandin-endoperoxide synthase 2 (rattus norvegicus))", "cox-2 (mus musculus)", "cox2 (saccharomyces cerevisiae s288c)", "cox2 (rattus norvegicus) (cytochrome c oxidase ii, mitochondrial (rattus norvegicus))", "cox-2 (rattus norvegicus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'crp'?	[ "crp (homo sapiens) (c-reactive protein (homo sapiens))", "c-reactive protein (homo sapiens)" ]	[ "crp (mus musculus) (c-reactive protein, pentraxin-related (mus musculus))", "crp (homo sapiens) (cysteine and glycine rich protein 1 (homo sapiens))", "crp (mus musculus) (cysteine rich protein 2 (mus musculus))", "crp (rattus norvegicus) (c-reactive protein (rattus norvegicus))", "crp (arabidopsis thaliana)", "crp1 (homo sapiens) (ccaat enhancer binding protein epsilon (homo sapiens))", "crp1 (mus musculus) (ccaat/enhancer binding protein epsilon (mus musculus))", "crp (rattus norvegicus) (proline rich 4 (rattus norvegicus))" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'csf1'?	[ "csf1 (homo sapiens)", "csf-1 (homo sapiens)", "colony stimulating factor 1 (homo sapiens)" ]	[ "csf1 (mus musculus)", "csf1 (rattus norvegicus)", "colony stimulating factor 1 (macrophage) (mus musculus)", "csf1 (saccharomyces cerevisiae s288c)", "colony stimulating factor 1 (rattus norvegicus)", "sdf1 (homo sapiens)", "csf1 (ovis aries)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'csf2'?	[ "csf2 (homo sapiens)", "colony stimulating factor 2 (homo sapiens)", "csf (homo sapiens) (colony stimulating factor 2 (homo sapiens))" ]	[ "csf2 (mus musculus)", "csf2 (rattus norvegicus)", "colony stimulating factor 2 (granulocyte-macrophage) (mus musculus)", "colony stimulating factor 2 (rattus norvegicus)", "csf2 (ovis aries)", "csf2 (cricetulus griseus)", "colony stimulating factor 2 (ovis aries)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'ifng'?	[ "ifng (homo sapiens)", "interferon gamma (homo sapiens)" ]	[ "ifng (mus musculus)", "ifng (rattus norvegicus)", "ifng (ovis aries)", "interferon gamma (mus musculus)", "ifn (homo sapiens)", "ifngm (homo sapiens)", "ifng (cricetulus griseus)", "ifng2 (rattus norvegicus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'il1a'?	[ "il1a (homo sapiens)", "il1-alpha (homo sapiens)", "interleukin 1 alpha (homo sapiens)", "il-1a (homo sapiens)", "il-1 alpha (homo sapiens)" ]	[ "il1a (mus musculus)", "il1a (rattus norvegicus)", "interleukin 1 alpha (mus musculus)", "il1a (ovis aries)", "il-1a (mus musculus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'il1b'?	[ "il1b (homo sapiens)", "il1beta (homo sapiens)", "il1-beta (homo sapiens)", "interleukin 1 beta (homo sapiens)" ]	[ "il1b (mus musculus)", "il1b (rattus norvegicus)", "interleukin 1 beta (mus musculus)", "il-1beta (mus musculus)", "interleukin 1 beta (rattus norvegicus)", "il-1b (mus musculus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'il2'?	[ "il2 (homo sapiens)", "interleukin 2 (homo sapiens)", "il-2 (homo sapiens)" ]	[ "il2 (mus musculus)", "interleukin 2 (mus musculus)", "il2 (rattus norvegicus)", "il-2 (mus musculus)", "interleukin 2 (rattus norvegicus)", "il22 (homo sapiens)", "il22 (mus musculus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'il4'?	[ "il4 (homo sapiens)", "interleukin 4 (homo sapiens)", "il-4 (homo sapiens)" ]	[ "il4 (mus musculus)", "interleukin 4 (mus musculus)", "il-4 (mus musculus)", "il4 (rattus norvegicus)", "interleukin 4 (rattus norvegicus)", "il4 (ovis aries)", "interleukin 4 (ovis aries)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'il6'?	[ "il6 (homo sapiens)", "interleukin 6 (homo sapiens)", "il-6 (homo sapiens)" ]	[ "il6 (mus musculus)", "il6 (rattus norvegicus)", "interleukin 6 (mus musculus)", "nf-il6 (homo sapiens)", "nf-il6 (mus musculus)", "il-6 (mus musculus)", "interleukin 6 (rattus norvegicus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.
What is the biomedical concept corresponding to 'il8'?	[ "il8 (homo sapiens)", "cxcl8 (homo sapiens)" ]	[ "il8 (mus musculus)", "il8 (ovis aries)", "il8 (danio rerio)", "il8 (canis lupus familiaris)", "il7 (homo sapiens)", "il7 (mus musculus)", "ccl8 (homo sapiens)", "ccl8 (mus musculus)" ]	Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', answer the user's query.

What is the biomedical concept corresponding to 'type i interferon'?

[ "ifnb1 (mus musculus)" ]

[ "ifn (homo sapiens)", "interferon alpha 1 (mus musculus)", "ifn1@ (homo sapiens)", "ifna (mus musculus)", "ifnb1 (homo sapiens)", "interferon, alpha 1 (rattus norvegicus)", "ifng (homo sapiens)", "interferon, type 1, cluster (homo sapiens)", "interferon alpha 1 (homo sapiens)" ]

Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', answer the user's query.

What is the biomedical concept corresponding to 'cd8alpha'?

[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]

[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]

Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', answer the user's query.

What is the biomedical concept corresponding to 'interferon (ifn) consensus sequence-binding protein'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "icsbp1 (rattus norvegicus)", "h-icsbp (homo sapiens)", "cold inducible rna binding protein (mus musculus)", "sine oculis binding protein (mus musculus)", "ns1bp (homo sapiens)" ]

Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'In this study, we have characterized the phenotype and activation pattern of subsets of dendritic cells (DCs) in ICSBP(-/-) mice.', answer the user's query.

What is the biomedical concept corresponding to 'ifn'?

[ "ifng (mus musculus)" ]

[ "ifn (homo sapiens)", "ifng (homo sapiens)", "ifn-alpha (homo sapiens)", "ifna (mus musculus)", "ifna@ (homo sapiens)", "ifna (homo sapiens) (interferon, type 1, cluster (homo sapiens))", "ifnaa (mus musculus)", "ifn1@ (homo sapiens)", "interferon kappa (homo sapiens)" ]

Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.

What is the biomedical concept corresponding to 'cd11c'?

[ "cd11c (mus musculus)" ]

[ "cd11c (homo sapiens)", "cd11b (mus musculus)", "cd103 (mus musculus)", "cd11b (homo sapiens)", "cd14 (mus musculus)", "cd103 (homo sapiens)", "cd1 (homo sapiens) (cd1a molecule (homo sapiens))", "cd64 (mus musculus)", "cd1 (mus musculus) (cd1 antigen complex (mus musculus))" ]

Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.

What is the biomedical concept corresponding to 'b220'?

[ "b220 (mus musculus)", "cd45 (mus musculus)", "cd45r (mus musculus)" ]

[ "b220 (homo sapiens)", "cd45 (homo sapiens)", "cd45r (homo sapiens)", "cd79a (mus musculus)", "cd79a (homo sapiens)", "cd20 (mus musculus)", "cd79a antigen (immunoglobulin-associated alpha) (mus musculus)" ]

Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.

What is the biomedical concept corresponding to 'ly6c'?

[ "ly6c (mus musculus)", "ly6c1 (mus musculus)" ]

[ "ly6c (rattus norvegicus)", "ly6-c antigen (rattus norvegicus)", "cd1c molecule (homo sapiens)", "cd1c (homo sapiens)", "ly6 (mus musculus)", "ly6g (mus musculus)", "ly67 (mus musculus)", "ly-c (mus musculus)" ]

Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.

What is the biomedical concept corresponding to 'cd11b'?

[ "cd11b (mus musculus)", "cd11b/cd18 (mus musculus)", "mac1 (mus musculus)" ]

[ "cd11b (homo sapiens)", "cd11b (rattus norvegicus)", "cd11b (danio rerio)", "mac-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens))", "cd61 (mus musculus)", "cd61 (homo sapiens)", "cd11b (ovis aries)" ]

Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', answer the user's query.

What is the biomedical concept corresponding to 'cd11c'?

[ "cd11c (mus musculus)" ]

[ "cd11c (homo sapiens)", "cd11b (mus musculus)", "cd103 (mus musculus)", "cd11b (homo sapiens)", "cd14 (mus musculus)", "cd103 (homo sapiens)", "cd1 (homo sapiens) (cd1a molecule (homo sapiens))", "cd64 (mus musculus)", "cd1 (mus musculus) (cd1 antigen complex (mus musculus))" ]

Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', answer the user's query.

What is the biomedical concept corresponding to 'type i ifns'?

[ "ifnb1 (mus musculus)" ]

[ "ifn (homo sapiens)", "ifng (homo sapiens)", "ifna (mus musculus)", "stat1 (homo sapiens)", "ifnb1 (homo sapiens)", "ifng (mus musculus)", "stat1 (mus musculus)", "ifn1@ (homo sapiens)", "interferon, type 1, cluster (homo sapiens)" ]

Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', answer the user's query.

What is the biomedical concept corresponding to 'cd8alpha'?

[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]

[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]

Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', answer the user's query.

What is the biomedical concept corresponding to 'cd8alpha'?

[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]

[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]

Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', answer the user's query.

What is the biomedical concept corresponding to 'cd8alpha'?

[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]

[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]

Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', answer the user's query.

What is the biomedical concept corresponding to 'intercellular adhesion molecule [icam]-1'?

[ "icam1 (mus musculus)", "icam-1 (mus musculus)", "intercellular adhesion molecule 1 (mus musculus)" ]

[ "icam1 (homo sapiens)", "intercellular adhesion molecule 1 (homo sapiens)", "icam1 (rattus norvegicus)", "cd51 (homo sapiens)", "cd51 (mus musculus)", "intercellular adhesion molecule 1 (rattus norvegicus)", "icam (rattus norvegicus)" ]

Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.

What is the biomedical concept corresponding to 'cd40'?

[ "cd40 (mus musculus)", "cd40 antigen (mus musculus)", "p50 (mus musculus) (cd40 antigen (mus musculus))" ]

[ "cd40 (homo sapiens)", "cd40 molecule (homo sapiens)", "p50 (homo sapiens) (cd40 molecule (homo sapiens))", "cd40 (rattus norvegicus)", "cd40 molecule (rattus norvegicus)", "cd40l (homo sapiens)", "cd40l (mus musculus)" ]

Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.

What is the biomedical concept corresponding to 'cd80'?

[ "cd80 (mus musculus)", "cd80 antigen (mus musculus)" ]

[ "cd80 (homo sapiens)", "cd80 molecule (homo sapiens)", "cd80 (rattus norvegicus)", "cd80 molecule (rattus norvegicus)", "cd86 (mus musculus)", "cd86 (homo sapiens)", "b7 (mus musculus) (cd86 antigen (mus musculus))", "cd86 antigen (mus musculus)" ]

Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.

What is the biomedical concept corresponding to 'cd86'?

[ "cd86 (mus musculus)", "cd86 antigen (mus musculus)", "b7 (mus musculus) (cd86 antigen (mus musculus))" ]

[ "cd86 (homo sapiens)", "cd86 molecule (homo sapiens)", "cd86 (rattus norvegicus)", "cd86 molecule (rattus norvegicus)", "cd86 expression in activated macrophages (mus musculus)", "cd80 (mus musculus)", "cd80 (homo sapiens)" ]

Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.

What is the biomedical concept corresponding to 'ccr7'?

[ "ccr7 (mus musculus)", "c-c motif chemokine receptor 7 (mus musculus)" ]

[ "ccr7 (homo sapiens)", "ccr7 (rattus norvegicus)", "ccr7 (danio rerio)", "c-c motif chemokine receptor 7 (homo sapiens)", "ccr2 (homo sapiens)", "ccr2 (mus musculus)", "cxcr7 (homo sapiens)", "cxcr7 (mus musculus)" ]

Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.

What is the biomedical concept corresponding to 'ccr2'?

[ "ccr2 (mus musculus)", "ccr2b (mus musculus)", "c-c motif chemokine receptor 2 (mus musculus)" ]

[ "ccr2 (homo sapiens)", "ccr2 (rattus norvegicus)", "ccr2b (homo sapiens)", "ccr5 (homo sapiens)", "ccr5 (mus musculus)", "c-c motif chemokine receptor 2 (homo sapiens)", "ccr2 (danio rerio)" ]

Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.

What is the biomedical concept corresponding to 'ccr6'?

[ "ccr6 (mus musculus)", "ccr-6 (mus musculus)", "c-c motif chemokine receptor 6 (mus musculus)" ]

[ "ccr6 (homo sapiens)", "ccr-6 (homo sapiens)", "ccr6 (rattus norvegicus)", "c-c motif chemokine receptor 6 (homo sapiens)", "c-c motif chemokine receptor 6 (rattus norvegicus)", "c-x-c motif chemokine receptor 6 (mus musculus)", "cxcr6 (homo sapiens)" ]

Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', answer the user's query.

What is the biomedical concept corresponding to 'toll-like receptor (tlr)3'?

[ "toll-like receptor 3 (mus musculus)", "tlr3 (mus musculus)" ]

[ "toll like receptor 3 (homo sapiens)", "toll-like receptor 3 (rattus norvegicus)", "tlr3 (homo sapiens)", "toll-3 (drosophila melanogaster)", "toll3 (drosophila melanogaster)", "tlr3 (rattus norvegicus)", "toll-like receptor 3 (danio rerio)", "toll-like receptor 3 (dermatophagoides pteronyssinus)" ]

Given the context 'In addition, these cells were unable to undergo full phenotypic activation upon in vitro culture in presence of maturation stimuli such as lipopolysaccharide or poly (I:C), which paralleled with lack of Toll-like receptor (TLR)3 mRNA expression.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'Finally, cytokine expression pattern was also altered in ICSBP(-/-)', answer the user's query.

What is the biomedical concept corresponding to 'interleukin (il)-12p40'?

[ "il-12p40 (mus musculus)", "p40 (mus musculus) (interleukin 12b (mus musculus))", "il12p40 (mus musculus)", "interleukin 12b (mus musculus)", "il-12b (mus musculus)" ]

[ "interleukin 12b (homo sapiens)", "il-12b (homo sapiens)", "interleukin 12a (mus musculus)", "interleukin 12a (homo sapiens)", "il-12a (homo sapiens)" ]

Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', answer the user's query.

What is the biomedical concept corresponding to 'il-15'?

[ "interleukin 15 (mus musculus)", "il-15 (mus musculus)", "il15 (mus musculus)" ]

[ "interleukin 15 (homo sapiens)", "il-15 (homo sapiens)", "interleukin 15 (rattus norvegicus)", "il15 (homo sapiens)", "interleukin 15 (ovis aries)", "il5 (homo sapiens)", "interleukin 15 (cricetulus griseus)" ]

Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', answer the user's query.

What is the biomedical concept corresponding to 'il-4'?

[ "interleukin 4 (mus musculus)", "il-4 (mus musculus)", "il4 (mus musculus)" ]

[ "interleukin 4 (homo sapiens)", "il-4 (homo sapiens)", "il4 (homo sapiens)", "interleukin 4 (rattus norvegicus)", "interleukin 4 (ovis aries)", "il-4 (ovis aries)", "il4 (ovis aries)" ]

Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.

What is the biomedical concept corresponding to 'cd8alpha'?

[ "cd8a (mus musculus)", "cd8 subunit alpha (mus musculus)" ]

[ "cd8alpha (homo sapiens)", "cd8a (homo sapiens)", "cd8 subunit alpha (homo sapiens)", "cd8a (rattus norvegicus)", "cd8 subunit alpha (rattus norvegicus)", "cd8 (homo sapiens)", "cd8 subunit beta (homo sapiens)", "cd8b1 (mus musculus)" ]

Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.

What is the biomedical concept corresponding to 'icsbp'?

[ "icsbp (mus musculus)", "icsbp1 (mus musculus)" ]

[ "icsbp (homo sapiens)", "icsbp1 (homo sapiens)", "icsbp (rattus norvegicus)", "h-icsbp (homo sapiens)", "icsbp1 (rattus norvegicus)", "ilbp (homo sapiens)", "ilbp (mus musculus)", "illbp (mus musculus)" ]

Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', answer the user's query.

What is the biomedical concept corresponding to 'sarco(endo)plasmic reticulum ca2+-atpase-2'?

[ "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "serca2 (homo sapiens)", "atp2a2 (homo sapiens)" ]

[ "atpase plasma membrane ca2+ transporting 2 (homo sapiens)", "atpase secretory pathway ca2+ transporting 2 (homo sapiens)", "serca2 (mus musculus)", "serca2 (rattus norvegicus)", "atpase, ca++ transporting, plasma membrane 2 (mus musculus)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (rattus norvegicus)", "atpase secretory pathway ca2+ transporting 2 (rattus norvegicus)" ]

Given the context 'Sarco(endo)plasmic reticulum Ca2+-ATPase-2 gene: structure and transcriptional regulation of the human gene.', answer the user's query.

What is the biomedical concept corresponding to 'serca1, 2, and 3'?

[ "serca1 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1 (homo sapiens)" ]

[ "serca1 (mus musculus)", "serca3 (homo sapiens)", "serca1 (rattus norvegicus)", "serca3 (mus musculus)", "serca2 (homo sapiens)", "serca3 (rattus norvegicus)", "serca2 (mus musculus)", "serca2a (mus musculus)" ]

Given the context 'The sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) belong to a family of active calcium transport enzymes encoded by the SERCA1, 2, and 3 genes.', answer the user's query.

What is the biomedical concept corresponding to 'serca2'?

[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]

[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]

Given the context 'In this study, we describe the complete structure of the human SERCA2 gene and its 5 -regulatory region.', answer the user's query.

What is the biomedical concept corresponding to 'serca2a'?

[ "serca2 (homo sapiens)", "atp2a2 (homo sapiens)" ]

[ "serca2a (mus musculus)", "serca2 (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "atp2a (homo sapiens)", "sercaii (rattus norvegicus)", "atp2a1 (homo sapiens)", "serca1 (homo sapiens)" ]

Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', answer the user's query.

What is the biomedical concept corresponding to 'serca2b'?

[ "serca2 (homo sapiens)", "atp2b (homo sapiens)" ]

[ "serca2b (mus musculus)", "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "sercaii (rattus norvegicus)", "serca3b (mus musculus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]

Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', answer the user's query.

What is the biomedical concept corresponding to 'serca2'?

[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]

[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]

Given the context 'The sequence of the proximal 225-bp regulatory region of the SERCA2 genes is 80% G+C-rich and is conserved among human, rabbit, rat, and mouse species.', answer the user's query.

What is the biomedical concept corresponding to 'sp1'?

[ "sp1 transcription factor (homo sapiens)", "sp1 (homo sapiens) (sp1 transcription factor (homo sapiens))" ]

[ "sp1 (mus musculus)", "sp1 (arabidopsis thaliana)", "sp1 transcription factor (rattus norvegicus)", "sp1 (rattus norvegicus)", "sp1 (xenopus laevis)", "h-sp1 (homo sapiens)", "sp1 (danio rerio)", "sp1 (cricetulus griseus)" ]

Given the context 'It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE).', answer the user's query.

What is the biomedical concept corresponding to 'gata-4, -5, -6'?

[ "gata6 (rattus norvegicus)", "gata binding protein 6 (rattus norvegicus)" ]

[ "gata-6 (mus musculus)", "gata6 (mus musculus)", "gata6 (homo sapiens)", "gata-4 (mus musculus)", "gata binding protein 6 (homo sapiens)", "gata5 (rattus norvegicus)", "gata5 (mus musculus)", "gata binding protein 6 (mus musculus)" ]

Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.

What is the biomedical concept corresponding to 'nkx-2.5'?

[ "nkx-2.5 (mus musculus)" ]

[ "nkx-5.2 (mus musculus)", "nkx-2.3 (mus musculus)", "nkx-5.1 (mus musculus)", "nkx-2.2 (mus musculus)", "nkx-5.1 (homo sapiens)", "nkx-2.5 (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis))", "nkx-1.2 (mus musculus)", "nkx-2.5 (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis))", "nkx-2.6 (mus musculus)" ]

Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.

What is the biomedical concept corresponding to 'csx'?

[ "csx (mus musculus)" ]

[ "csx (homo sapiens)", "csx (rattus norvegicus)", "csx1 (homo sapiens)", "csx (xenopus laevis) (nk2 homeobox 5 s homeolog (xenopus laevis))", "csx (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis))", "csx3 (homo sapiens)", "scx (homo sapiens)", "scx (cricetulus griseus)", "csx2 (homo sapiens)" ]

Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.

What is the biomedical concept corresponding to 'otf-1'?

[ "otf1 (homo sapiens)" ]

[ "otf-1 (mus musculus)", "otf1 (mus musculus)", "otf-1 (xenopus laevis)", "obf-1 (mus musculus)", "pou1f1 (mus musculus)", "pou domain, class 1, transcription factor 1 (mus musculus)", "oligodendrocyte transcription factor 1 (mus musculus)", "pou1f1 (rattus norvegicus)", "pou1f1 (homo sapiens)" ]

Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.

What is the biomedical concept corresponding to 'srf'?

[ "srf (homo sapiens)", "serum response factor (homo sapiens)" ]

[ "srf (mus musculus)", "srf (rattus norvegicus)", "srf1 (homo sapiens)", "srf (xenopus laevis)", "serum response factor (mus musculus)", "srf (danio rerio)", "srf-1 (homo sapiens)", "serum response factor (rattus norvegicus)" ]

Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.

What is the biomedical concept corresponding to 'ap-2'?

[ "ap-2 (homo sapiens)", "transcription factor ap-2 alpha (homo sapiens)" ]

[ "ap-2 (mus musculus)", "transcription factor ap-2 (drosophila melanogaster)", "ap2 (mus musculus) (transcription factor ap-2, alpha (mus musculus))", "ap-2 (drosophila melanogaster) (transcription factor ap-2 (drosophila melanogaster))", "transcription factor ap-2, alpha (mus musculus)", "ap-2 (a) (mus musculus)", "ap-2(beta) (mus musculus)", "transcription factor ap-2 alpha (rattus norvegicus)" ]

Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', answer the user's query.

What is the biomedical concept corresponding to 'serca2'?

[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]

[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]

Given the context 'Upstream from position -1.5 kb, there is no significant homology among the SERCA2 genes cloned.', answer the user's query.

What is the biomedical concept corresponding to 'serca2'?

[ "serca2 (homo sapiens)", "atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)", "atp2a2 (homo sapiens)" ]

[ "serca2 (mus musculus)", "serca2a (mus musculus)", "serca2 (rattus norvegicus)", "serca2b (mus musculus)", "sercaii (rattus norvegicus)", "serca2 (danio rerio)", "atp2a (homo sapiens)" ]

Given the context 'In this study, we report the cloning of 2.4 kb of 5-regulatory region and demonstrate that the proximal promoter region is sufficient for expression in cardiac myocytes, and the region from -225 to -1232 bp contains regulatory DNA elements which down-regulate the expression of the SERCA2 gene in neonatal cardiomyocytes.', answer the user's query.

What is the biomedical concept corresponding to 'nfkappab'?

[ "nfkappab (homo sapiens)", "nf-kappab (homo sapiens)", "nf-kappabeta (homo sapiens)", "nf-kb (homo sapiens)", "nuclear factor kappa b subunit 1 (homo sapiens)" ]

[ "nf-kappab (mus musculus)", "nfkb (rattus norvegicus)", "p65 nf-kappa b (mus musculus)", "p65 nfkb (mus musculus)", "rela proto-oncogene, nf-kb subunit (homo sapiens)" ]

Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', answer the user's query.

What is the biomedical concept corresponding to 'rage'?

[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]

[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]

Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', answer the user's query.

What is the biomedical concept corresponding to 'receptor for advanced glycation end products'?

[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))", "advanced glycosylation end-product specific receptor (homo sapiens)", "ager (homo sapiens)" ]

[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "advanced glycosylation end product-specific receptor (mus musculus)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "ager (mus musculus)", "advanced glycosylation end product-specific receptor (rattus norvegicus)", "rage1 (homo sapiens)", "rage1 (mus musculus)" ]

Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', answer the user's query.

What is the biomedical concept corresponding to 'rage'?

[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]

[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]

Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.

What is the biomedical concept corresponding to 's100a8'?

[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]

[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]

Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.

What is the biomedical concept corresponding to 's100a9'?

[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]

[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]

Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.

What is the biomedical concept corresponding to 'rage'?

[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]

[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]

Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.

What is the biomedical concept corresponding to 'nfkappab'?

[ "nfkappab (homo sapiens)", "nf-kappab (homo sapiens)", "nf-kappabeta (homo sapiens)", "nf-kb (homo sapiens)", "nuclear factor kappa b subunit 1 (homo sapiens)" ]

[ "nf-kappab (mus musculus)", "nfkb (rattus norvegicus)", "p65 nf-kappa b (mus musculus)", "p65 nfkb (mus musculus)", "rela proto-oncogene, nf-kb subunit (homo sapiens)" ]

Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', answer the user's query.

What is the biomedical concept corresponding to 'rage'?

[ "rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))" ]

[ "rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus))", "rage1 (homo sapiens)", "rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus))", "rage1 (mus musculus)", "rage-1 (homo sapiens)", "rage (homo sapiens) (mok protein kinase (homo sapiens))", "rage (mus musculus) (mok protein kinase (mus musculus))", "rage (rattus norvegicus) (mok protein kinase (rattus norvegicus))", "gfr (homo sapiens)" ]

Given the context 'Human umbilical vein endothelial cells (HUVEC) were preincubated for 72 h with AGE-albumin or unmodified albumin for control, whereas AGE-albumin induction resulted in an upregulation of RAGE.', answer the user's query.

What is the biomedical concept corresponding to 's100a8'?

[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]

[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]

Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', answer the user's query.

What is the biomedical concept corresponding to 's100a9'?

[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]

[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]

Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', answer the user's query.

What is the biomedical concept corresponding to 's100a8'?

[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]

[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]

Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.

What is the biomedical concept corresponding to 's100a9'?

[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]

[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]

Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.

What is the biomedical concept corresponding to 'il-6'?

[ "interleukin 6 (homo sapiens)", "il-6 (homo sapiens)", "il6 (homo sapiens)" ]

[ "interleukin 6 (mus musculus)", "il-6 (mus musculus)", "interleukin 6 (rattus norvegicus)", "il6 (mus musculus)", "il6 (rattus norvegicus)", "interleukin 6 (ovis aries)", "nf-il6 (mus musculus)" ]

Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.

What is the biomedical concept corresponding to 'icam-1'?

[ "icam1 (homo sapiens)", "intercellular adhesion molecule 1 (homo sapiens)" ]

[ "icam1 (mus musculus)", "icam-1 (mus musculus)", "intercellular adhesion molecule 1 (mus musculus)", "icam1 (rattus norvegicus)", "cd51 (homo sapiens)", "vcam-1 (mus musculus)", "cd51 (mus musculus)", "vcam1 (homo sapiens)" ]

Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.

What is the biomedical concept corresponding to 'vcam-1'?

[ "vcam1 (homo sapiens)", "vascular cell adhesion molecule 1 (homo sapiens)" ]

[ "vcam1 (mus musculus)", "vcam-1 (mus musculus)", "vcam1 (rattus norvegicus)", "vascular cell adhesion molecule 1 (mus musculus)", "vcam-1 (ovis aries)", "platelet/endothelial cell adhesion molecule 1 (mus musculus)", "platelet and endothelial cell adhesion molecule 1 (homo sapiens)", "icam-1 (mus musculus)" ]

Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.

What is the biomedical concept corresponding to 'mcp1'?

[ "mcp1 (homo sapiens)", "mcp-1 (homo sapiens)" ]

[ "mcp1 (mus musculus)", "mcp-1 (mus musculus) (c-c motif chemokine ligand 2 (mus musculus))", "ccl1 (homo sapiens)", "mcp-1 (mus musculus) (mast cell protease 1 (mus musculus))", "mcp-1 (rattus norvegicus)", "ccl1 (mus musculus)", "mcp1 (saccharomyces cerevisiae s288c)", "mcp1 (ovis aries)" ]

Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', answer the user's query.

What is the biomedical concept corresponding to 's100a8'?

[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]

[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]

Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.

What is the biomedical concept corresponding to 's100a9'?

[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]

[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]

Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.

What is the biomedical concept corresponding to 's100a1'?

[ "s100a1 (homo sapiens)", "s100a (homo sapiens)", "s100 calcium binding protein a1 (homo sapiens)", "s100 (homo sapiens) (s100 calcium binding protein a1 (homo sapiens))" ]

[ "s100a1 (mus musculus)", "s100a1 (rattus norvegicus) (s100 calcium binding protein a1 (rattus norvegicus))", "s100 calcium binding protein a1 (mus musculus)", "cal (mus musculus) (s100 calcium binding protein a11 (mus musculus))", "s100a (mus musculus)", "s100a11 (homo sapiens)" ]

Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.

What is the biomedical concept corresponding to 's100b'?

[ "s100b (homo sapiens)", "s100-b (homo sapiens)", "s100beta (homo sapiens)", "s100 (homo sapiens) (s100 calcium binding protein b (homo sapiens))", "s100 calcium binding protein b (homo sapiens)" ]

[ "s100b (mus musculus)", "s100b (rattus norvegicus)", "s100 protein, beta polypeptide, neural (mus musculus)", "s100 calcium binding protein b (rattus norvegicus)", "s100 (mus musculus)" ]

Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', answer the user's query.

What is the biomedical concept corresponding to 's100a8'?

[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]

[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]

Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', answer the user's query.

What is the biomedical concept corresponding to 's100a9'?

[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]

[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]

Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', answer the user's query.

What is the biomedical concept corresponding to 'p38'?

[ "p38alpha (homo sapiens)", "p38 (homo sapiens) (mitogen-activated protein kinase 14 (homo sapiens))" ]

[ "p38alpha (mus musculus)", "p38 (homo sapiens) (mitogen-activated protein kinase 1 (homo sapiens))", "p38 (rattus norvegicus)", "p38 (mus musculus) (mitogen-activated protein kinase 14 (mus musculus))", "p38a (mus musculus)", "p38alpha (rattus norvegicus)", "p38-alpha (mus musculus)", "p38mapk (mus musculus)" ]

Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', answer the user's query.

What is the biomedical concept corresponding to 's100a8'?

[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]

[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]

Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', answer the user's query.

What is the biomedical concept corresponding to 's100a9'?

[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]

[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]

Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', answer the user's query.

What is the biomedical concept corresponding to 's100a8'?

[ "s100a8 (homo sapiens)", "s100 calcium binding protein a8 (homo sapiens)", "s100-a8 (homo sapiens)", "mrp8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))", "p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens))" ]

[ "s100a8 (mus musculus)", "s100 calcium binding protein a8 (calgranulin a) (mus musculus)", "p8 (mus musculus) (s100 calcium binding protein a8 (calgranulin a) (mus musculus))", "s100a8 (rattus norvegicus)", "s100 calcium binding protein a8 (rattus norvegicus)" ]

Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', answer the user's query.

What is the biomedical concept corresponding to 's100a9'?

[ "s100a9 (homo sapiens)", "s100 calcium binding protein a9 (homo sapiens)", "s100-a9 (homo sapiens)", "p14 (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))", "mif (homo sapiens) (s100 calcium binding protein a9 (homo sapiens))" ]

[ "s100a9 (mus musculus)", "s100 calcium binding protein a9 (calgranulin b) (mus musculus)", "s100a9 (rattus norvegicus)", "p14 (mus musculus) (s100 calcium binding protein a9 (calgranulin b) (mus musculus))", "s100 calcium binding protein a9 (rattus norvegicus)" ]

Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', answer the user's query.

What is the biomedical concept corresponding to 'growth hormone'?

[ "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)", "gh1 (homo sapiens)" ]

[ "growth hormone (mus musculus)", "gh (mus musculus)", "gh (rattus norvegicus)", "growth hormone 1 (rattus norvegicus)", "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "growth hormone 2 (homo sapiens)", "growth hormone (ovis aries)" ]

Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', answer the user's query.

What is the biomedical concept corresponding to 'gh1'?

[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]

[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]

Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', answer the user's query.

What is the biomedical concept corresponding to 'gh1'?

[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]

[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]

Given the context 'OBJECTIVE: GH1 gene presents a complex map of single nucleotide polymorphisms (SNPs) in the entire promoter, coding and noncoding regions.', answer the user's query.

What is the biomedical concept corresponding to 'gh1'?

[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]

[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]

Given the context 'The aim of the study was to establish the complete map of GH1 gene SNPs in our control normal population and to analyse its association with adult height.', answer the user's query.

What is the biomedical concept corresponding to 'gh1'?

[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]

[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]

Given the context 'DESIGN, SUBJECTS AND MEASUREMENTS: A systematic GH1 gene analysis was designed in a control population of 307 adults of both sexes with height normally distributed within normal range for the same population: -2 standard deviation scores (SDS) to +2 SDS.', answer the user's query.

What is the biomedical concept corresponding to 'gh1'?

[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]

[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]

Given the context 'This study established the GH1 gene sequence variation map in a normal adult height control population confirming the high density of SNPs in a relatively small gene.', answer the user's query.

What is the biomedical concept corresponding to 'gh1'?

[ "gh1 (homo sapiens)", "gh (homo sapiens) (growth hormone 1 (homo sapiens))", "growth hormone 1 (homo sapiens)" ]

[ "gh1 (rattus norvegicus) (growth hormone 1 (rattus norvegicus))", "gh1 (rattus norvegicus) (gonadotropin releasing hormone receptor (rattus norvegicus))", "gh1 (cricetulus griseus)", "gh1 (ovis aries)", "gh1 (danio rerio)", "gh (mus musculus)", "gh1b1 (mus musculus)" ]

Given the context 'Systematic GH1 gene analysis in patients with growth delay and suspected GH deficiency/insufficiency will clarify whether different SNP frequencies and/or the presence of different sequence changes may be associated with phenotypes in them.', answer the user's query.

What is the biomedical concept corresponding to 'ccr2'?

[ "ccr2 (homo sapiens)", "ccr2b (homo sapiens)", "c-c motif chemokine receptor 2 (homo sapiens)" ]

[ "ccr2 (mus musculus)", "ccr2 (rattus norvegicus)", "ccr2b (mus musculus)", "ccr5 (homo sapiens)", "c-c motif chemokine receptor 2 (mus musculus)", "ccr5 (mus musculus)", "ccr2 (danio rerio)" ]