query stringlengths 53 129 | positive listlengths 1 10 | negative listlengths 10 10 | system stringlengths 50 956 |
|---|---|---|---|
What is the biomedical concept corresponding to 'mtnr1a'? | [
"mtnr1a (mus musculus)"
] | [
"mtnr1a (homo sapiens)",
"mtnr1a (xenopus tropicalis) (melatonin receptor 1a (xenopus tropicalis))",
"mtnr1b (homo sapiens)",
"mtnr1a (rattus norvegicus)",
"melatonin receptor 1a (xenopus tropicalis) (mtnr1a (xenopus tropicalis))",
"mtnr1aa (danio rerio)",
"mtnr1b (mus musculus)",
"mtnr1a.l (xenopus l... | Given the context 'These results suggested that the melatonin receptors MTNR1A and MTNR1B are essential to repress hCG-induced ER stress and cell apoptosis.', answer the user's query. |
What is the biomedical concept corresponding to 'mtnr1b'? | [
"mtnr1b (mus musculus)",
"mt2 (mus musculus) (melatonin receptor 1b (mus musculus))"
] | [
"mtnr1b (homo sapiens)",
"mtnr1b (rattus norvegicus)",
"mtnr1a (homo sapiens)",
"mtnr1b (bos taurus)",
"mt2 (homo sapiens) (melatonin receptor 1b (homo sapiens))",
"mtnr1b.l (xenopus laevis)",
"mtnr1ba (danio rerio)",
"mtnr1bb (danio rerio)",
"mtnr1b (danio rerio)",
"mtnr1b (xenopus laevis)"
] | Given the context 'These results suggested that the melatonin receptors MTNR1A and MTNR1B are essential to repress hCG-induced ER stress and cell apoptosis.', answer the user's query. |
What is the biomedical concept corresponding to 'hcg'? | [
"hcgb (homo sapiens) (chorionic gonadotropin subunit beta 3 (homo sapiens))"
] | [
"hcg-1 (homo sapiens)",
"hcgi (homo sapiens)",
"hcgv (homo sapiens)",
"hcg-v (homo sapiens)",
"hcg (xenopus laevis) (glycoprotein hormones, alpha polypeptide s homeolog (xenopus laevis))",
"hcg (homo sapiens) (glycoprotein hormones, alpha polypeptide (homo sapiens))",
"hcg (mus musculus) (glycoprotein h... | Given the context 'These results suggested that the melatonin receptors MTNR1A and MTNR1B are essential to repress hCG-induced ER stress and cell apoptosis.', answer the user's query. |
What is the biomedical concept corresponding to 'melatonin receptors'? | [
"melatonin receptor 1b (mus musculus)"
] | [
"melatonin receptor 1a (homo sapiens)",
"melatonin receptor 1a (gallus gallus)",
"mr (mus musculus) (melatonin receptor 1a (mus musculus))",
"melatonin receptor 1a (mus musculus)",
"melatonin receptor 1b (homo sapiens)",
"melatonin receptor 1b (gallus gallus)",
"melatonin receptor 1a (xenopus tropicalis... | Given the context 'Our studies demonstrated that the mammalian melatonin receptors MT1 and MT2 are involved in testosterone synthesis via mediating multiple cell pathways.', answer the user's query. |
What is the biomedical concept corresponding to 'thymic stromal lymphopoietin'? | [
"thymic stromal lymphopoietin (homo sapiens)",
"tslp (homo sapiens)"
] | [
"thymic stromal lymphopoietin (mus musculus)",
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (cricetulus griseus)",
"thymic stromal lymphopoietin (rattus norvegicus)",
"thymopoietin (homo sapiens)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymp... | Given the context 'Use of Physcion to Improve Atopic Dermatitis-Like Skin Lesions through Blocking of Thymic Stromal Lymphopoietin.', answer the user's query. |
What is the biomedical concept corresponding to 'thymic stromal lymphopoietin'? | [
"thymic stromal lymphopoietin (homo sapiens)",
"tslp (homo sapiens)"
] | [
"thymic stromal lymphopoietin (mus musculus)",
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (cricetulus griseus)",
"thymic stromal lymphopoietin (rattus norvegicus)",
"thymopoietin (homo sapiens)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymp... | Given the context 'However, the therapeutic effect of physcion on atopic dermatitis (AD) through the inhibition of thymic stromal lymphopoietin (TSLP) level remains largely unknown.', answer the user's query. |
What is the biomedical concept corresponding to 'tslp'? | [
"tslp (homo sapiens)",
"thymic stromal lymphopoietin (homo sapiens)"
] | [
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (sus scrofa)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymphopoietin (canis lupus familiaris) (tslp (canis lupus familiaris))",
"thymic stromal lymphopoietin (bos taurus)",
"thymic stromal lymphopoie... | Given the context 'However, the therapeutic effect of physcion on atopic dermatitis (AD) through the inhibition of thymic stromal lymphopoietin (TSLP) level remains largely unknown.', answer the user's query. |
What is the biomedical concept corresponding to 'tslp'? | [
"tslp (homo sapiens)",
"thymic stromal lymphopoietin (homo sapiens)"
] | [
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (sus scrofa)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymphopoietin (canis lupus familiaris) (tslp (canis lupus familiaris))",
"thymic stromal lymphopoietin (bos taurus)",
"thymic stromal lymphopoie... | Given the context 'Treatment with physcion decreased production and mRNA expression levels of TSLP, IL-6, TNF-alpha, and IL-1beta in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'il-6'? | [
"il-6 (homo sapiens)",
"interleukin 6 (homo sapiens)",
"il6 (homo sapiens)",
"cdf (homo sapiens) (interleukin 6 (homo sapiens))",
"hgf (homo sapiens) (interleukin 6 (homo sapiens))"
] | [
"cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens))",
"lif interleukin 6 family cytokine (homo sapiens)",
"il-6 (xenopus laevis) (interleukin 6 s homeolog (xenopus laevis))",
"il-6 (xenopus laevis) (interleukin 6 l homeolog (xenopus laevis))",
"interleukin 6 (gallus gallus)",
"interleuk... | Given the context 'Treatment with physcion decreased production and mRNA expression levels of TSLP, IL-6, TNF-alpha, and IL-1beta in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'tnf-alpha'? | [
"tnfa (homo sapiens)",
"tnf (homo sapiens)",
"tumor necrosis factor (homo sapiens)",
"tnfsf2 (homo sapiens)"
] | [
"lymphotoxin alpha (homo sapiens)",
"tnf-alpha (drosophila melanogaster)",
"tnf-alpha (xenopus laevis) (tumor necrosis factor s homeolog (xenopus laevis))",
"tnfsf1 (homo sapiens)",
"tnfc (homo sapiens)",
"tnf-alpha (xenopus laevis) (tumor necrosis factor l homeolog (xenopus laevis))",
"tnfa (xenopus la... | Given the context 'Treatment with physcion decreased production and mRNA expression levels of TSLP, IL-6, TNF-alpha, and IL-1beta in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1beta'? | [
"il1-beta (homo sapiens)",
"interleukin 1 beta (homo sapiens)",
"il1beta (homo sapiens)",
"il1b (homo sapiens)",
"il1f2 (homo sapiens)"
] | [
"il-1b (xenopus laevis) (interleukin 1 beta s homeolog (xenopus laevis))",
"il-1beta (mus musculus)",
"interleukin 1 beta (canis lupus familiaris)",
"il-1b (xenopus laevis) (interleukin 1 beta l homeolog (xenopus laevis))",
"il1f4 (homo sapiens)",
"interleukin 1 beta (oryctolagus cuniculus)",
"il-1 (xen... | Given the context 'Treatment with physcion decreased production and mRNA expression levels of TSLP, IL-6, TNF-alpha, and IL-1beta in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'rip2'? | [
"rip2 (homo sapiens) (receptor interacting serine/threonine kinase 2 (homo sapiens))",
"ripk2 (homo sapiens)",
"receptor interacting serine/threonine kinase 2 (homo sapiens)"
] | [
"rip-1 (homo sapiens) (receptor interacting serine/threonine kinase 1 (homo sapiens))",
"rip1 (homo sapiens) (receptor interacting serine/threonine kinase 1 (homo sapiens))",
"rip (homo sapiens) (receptor interacting serine/threonine kinase 1 (homo sapiens))",
"rip3 (xenopus tropicalis) (receptor interacting ... | Given the context 'Physcion reduced the expression levels of RIP2/caspase-1 and phospho (p)ERK/pJNK/pp38 in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'caspase-1'? | [
"caspase 1 (homo sapiens)",
"ice (homo sapiens) (caspase 1 (homo sapiens))",
"casp1 (homo sapiens)"
] | [
"caspase-1 (xenopus laevis) (caspase 1 s homeolog (xenopus laevis))",
"caspase-1 (xenopus laevis) (caspase 1 l homeolog (xenopus laevis))",
"casp1a (xenopus laevis) (caspase 1 s homeolog (xenopus laevis))",
"casp1a (xenopus laevis) (caspase 1 l homeolog (xenopus laevis))",
"casp1-a (xenopus laevis) (caspase... | Given the context 'Physcion reduced the expression levels of RIP2/caspase-1 and phospho (p)ERK/pJNK/pp38 in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'erk'? | [
"erk (homo sapiens) (mitogen-activated protein kinase 1 (homo sapiens))",
"erk-2 (homo sapiens)"
] | [
"erk-1 (homo sapiens)",
"erk1 (homo sapiens)",
"erk (drosophila melanogaster) (rolled (drosophila melanogaster))",
"p-erk (drosophila melanogaster)",
"erk-6 (homo sapiens)",
"erk-a (drosophila melanogaster)",
"erk7 (homo sapiens)",
"erk6 (homo sapiens)",
"erk-4 (homo sapiens)",
"erk1 (drosophila m... | Given the context 'Physcion reduced the expression levels of RIP2/caspase-1 and phospho (p)ERK/pJNK/pp38 in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'jnk'? | [
"jnk (homo sapiens)",
"jnk1 (homo sapiens)"
] | [
"jnk (drosophila melanogaster)",
"p-jnk (drosophila melanogaster)",
"jnkk (homo sapiens)",
"jnk (bsk) (drosophila melanogaster)",
"jnk2 (homo sapiens)",
"jnkk (drosophila melanogaster)",
"d-jnk (drosophila melanogaster)",
"jnk3 (homo sapiens)",
"sapka/jnk (drosophila melanogaster)",
"jnk/sapk (dro... | Given the context 'Physcion reduced the expression levels of RIP2/caspase-1 and phospho (p)ERK/pJNK/pp38 in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'p38'? | [
"p38alpha (homo sapiens)"
] | [
"p38 (drosophila melanogaster) (p38a map kinase (drosophila melanogaster))",
"p38 alpha (drosophila melanogaster)",
"p38 (drosophila melanogaster) (p38c map kinase (drosophila melanogaster))",
"p38b (homo sapiens)",
"p38 (drosophila melanogaster) (p38b map kinase (drosophila melanogaster))",
"p38gamma (ho... | Given the context 'Physcion reduced the expression levels of RIP2/caspase-1 and phospho (p)ERK/pJNK/pp38 in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ikkbeta'? | [
"ikk-beta (homo sapiens)",
"ikkb (homo sapiens)",
"ikk2 (homo sapiens)",
"ikk-2 (homo sapiens)",
"inhibitor of nuclear factor kappa b kinase subunit beta (homo sapiens)"
] | [
"ikk (drosophila melanogaster) (i-kappab kinase beta (drosophila melanogaster))",
"ikk-beta (drosophila melanogaster)",
"ikkbeta (drosophila melanogaster)",
"ikk-alpha (homo sapiens)",
"ikkgammabeta (drosophila melanogaster)",
"ikka (homo sapiens)",
"ikk-gamma (homo sapiens)",
"ikkb (drosophila melano... | Given the context 'Physcion suppressed the expression levels of pIKKbeta/NF-kappaB/pIkB in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kappab'? | [
"nf-kappab (homo sapiens)",
"nf-kappabeta (homo sapiens)",
"nf-kb (homo sapiens)",
"nf-kappa-b1 (homo sapiens)",
"nuclear factor kappa b subunit 1 (homo sapiens)",
"nf-kb1 (homo sapiens)"
] | [
"nf-kappab (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog (xenopus laevis))",
"nf-kappab (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog (xenopus laevis))",
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
... | Given the context 'Physcion suppressed the expression levels of pIKKbeta/NF-kappaB/pIkB in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ikb'? | [
"ikba (homo sapiens)"
] | [
"ikbb (homo sapiens)",
"ikb-epsilon (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon s homeolog (xenopus laevis))",
"ikb-epsilon (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon l homeolog (xenopus laev... | Given the context 'Physcion suppressed the expression levels of pIKKbeta/NF-kappaB/pIkB in activated HMC-1 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'tslp'? | [
"thymic stromal lymphopoietin (mus musculus)"
] | [
"tslp (homo sapiens)",
"thymic stromal lymphopoietin (homo sapiens)",
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (sus scrofa)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymphopoietin (canis lupus familiaris) (tslp (canis lupus familiaris))",
... | Given the context 'Moreover, physcion attenuated the production levels of TSLP, IL-4, IL-6, TNF-, and IFN-gamma from activated splenocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'il-4'? | [
"interleukin 4 (mus musculus)",
"il-4 (mus musculus)"
] | [
"interleukin 4 (homo sapiens)",
"il-4 (homo sapiens)",
"il4 (homo sapiens)",
"il-4 (canis lupus familiaris)",
"interleukin 4 (canis lupus familiaris)",
"interleukin 4 (cricetulus griseus)",
"interleukin-4 (gallus gallus)",
"il4 (canis lupus familiaris)",
"interleukin 4 (gallus gallus)",
"il-4 (bos... | Given the context 'Moreover, physcion attenuated the production levels of TSLP, IL-4, IL-6, TNF-, and IFN-gamma from activated splenocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'il-6'? | [
"interleukin 6 (mus musculus)",
"il-6 (mus musculus)"
] | [
"il-6 (homo sapiens)",
"interleukin 6 (homo sapiens)",
"il6 (homo sapiens)",
"cdf (homo sapiens) (interleukin 6 (homo sapiens))",
"hgf (homo sapiens) (interleukin 6 (homo sapiens))",
"cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens))",
"lif interleukin 6 family cytokine (homo sapiens... | Given the context 'Moreover, physcion attenuated the production levels of TSLP, IL-4, IL-6, TNF-, and IFN-gamma from activated splenocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'ifn-gamma'? | [
"interferon gamma (mus musculus)",
"ifn-g (mus musculus)"
] | [
"interferon gamma (homo sapiens)",
"ifn-gamma (gallus gallus)",
"interferon gamma (gallus gallus)",
"interferon gamma (mus caroli)",
"interferon gamma (cricetulus griseus)",
"ifn-gamma (canis lupus familiaris)",
"ifng (homo sapiens)",
"interferon gamma (rattus norvegicus)",
"ifn-gamma (ovis aries)",... | Given the context 'Moreover, physcion attenuated the production levels of TSLP, IL-4, IL-6, TNF-, and IFN-gamma from activated splenocytes.', answer the user's query. |
What is the biomedical concept corresponding to 'tslp'? | [
"thymic stromal lymphopoietin (mus musculus)"
] | [
"tslp (homo sapiens)",
"thymic stromal lymphopoietin (homo sapiens)",
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (sus scrofa)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymphopoietin (canis lupus familiaris) (tslp (canis lupus familiaris))",
... | Given the context 'Oral administration of physcion improved the severity of 2,4-dinitrochlorobenzene-induced AD-like lesional skin through reducing infiltration of inflammatory cells and mast cells, and the protein and mRNA levels of TSLP, IL-4, and IL-6 in the lesional skin tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'il-4'? | [
"interleukin 4 (mus musculus)",
"il-4 (mus musculus)"
] | [
"interleukin 4 (homo sapiens)",
"il-4 (homo sapiens)",
"il4 (homo sapiens)",
"il-4 (canis lupus familiaris)",
"interleukin 4 (canis lupus familiaris)",
"interleukin 4 (cricetulus griseus)",
"interleukin-4 (gallus gallus)",
"il4 (canis lupus familiaris)",
"interleukin 4 (gallus gallus)",
"il-4 (bos... | Given the context 'Oral administration of physcion improved the severity of 2,4-dinitrochlorobenzene-induced AD-like lesional skin through reducing infiltration of inflammatory cells and mast cells, and the protein and mRNA levels of TSLP, IL-4, and IL-6 in the lesional skin tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'il-6'? | [
"interleukin 6 (mus musculus)",
"il-6 (mus musculus)"
] | [
"il-6 (homo sapiens)",
"interleukin 6 (homo sapiens)",
"il6 (homo sapiens)",
"cdf (homo sapiens) (interleukin 6 (homo sapiens))",
"hgf (homo sapiens) (interleukin 6 (homo sapiens))",
"cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens))",
"lif interleukin 6 family cytokine (homo sapiens... | Given the context 'Oral administration of physcion improved the severity of 2,4-dinitrochlorobenzene-induced AD-like lesional skin through reducing infiltration of inflammatory cells and mast cells, and the protein and mRNA levels of TSLP, IL-4, and IL-6 in the lesional skin tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'tslp'? | [
"thymic stromal lymphopoietin (mus musculus)"
] | [
"tslp (homo sapiens)",
"thymic stromal lymphopoietin (homo sapiens)",
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (sus scrofa)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymphopoietin (canis lupus familiaris) (tslp (canis lupus familiaris))",
... | Given the context 'Physcion attenuated histamine, IgE, TSLP, IL-4, IL-6, and TNF- levels in serum.', answer the user's query. |
What is the biomedical concept corresponding to 'il-4'? | [
"interleukin 4 (mus musculus)",
"il-4 (mus musculus)"
] | [
"interleukin 4 (homo sapiens)",
"il-4 (homo sapiens)",
"il4 (homo sapiens)",
"il-4 (canis lupus familiaris)",
"interleukin 4 (canis lupus familiaris)",
"interleukin 4 (cricetulus griseus)",
"interleukin-4 (gallus gallus)",
"il4 (canis lupus familiaris)",
"interleukin 4 (gallus gallus)",
"il-4 (bos... | Given the context 'Physcion attenuated histamine, IgE, TSLP, IL-4, IL-6, and TNF- levels in serum.', answer the user's query. |
What is the biomedical concept corresponding to 'il-6'? | [
"interleukin 6 (mus musculus)",
"il-6 (mus musculus)"
] | [
"il-6 (homo sapiens)",
"interleukin 6 (homo sapiens)",
"il6 (homo sapiens)",
"cdf (homo sapiens) (interleukin 6 (homo sapiens))",
"hgf (homo sapiens) (interleukin 6 (homo sapiens))",
"cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens))",
"lif interleukin 6 family cytokine (homo sapiens... | Given the context 'Physcion attenuated histamine, IgE, TSLP, IL-4, IL-6, and TNF- levels in serum.', answer the user's query. |
What is the biomedical concept corresponding to 'tslp'? | [
"thymic stromal lymphopoietin (mus musculus)"
] | [
"tslp (homo sapiens)",
"thymic stromal lymphopoietin (homo sapiens)",
"thymic stromal lymphopoietin (mus caroli)",
"thymic stromal lymphopoietin (sus scrofa)",
"thymic stromal lymphopoietin (oryctolagus cuniculus)",
"thymic stromal lymphopoietin (canis lupus familiaris) (tslp (canis lupus familiaris))",
... | Given the context 'These findings indicate that physcion could ameliorate AD-like skin lesions by inhibiting TSLP levels via caspase-1/MAPKs/NF-kB signalings, which would provide experimental evidence of the therapeutic potential of physcion for AD.', answer the user's query. |
What is the biomedical concept corresponding to 'nf-kb'? | [
"nf-kb1 (mus musculus)"
] | [
"nf-kb (homo sapiens)",
"nf-kb1 (homo sapiens)",
"nf-kb2 (homo sapiens)",
"rela proto-oncogene, nf-kb subunit (homo sapiens)",
"nf-kb (drosophila melanogaster) (dorsal (drosophila melanogaster))",
"nf-kappab (homo sapiens)",
"nf-kappa-b (xenopus laevis) (nuclear factor of kappa light polypeptide gene en... | Given the context 'These findings indicate that physcion could ameliorate AD-like skin lesions by inhibiting TSLP levels via caspase-1/MAPKs/NF-kB signalings, which would provide experimental evidence of the therapeutic potential of physcion for AD.', answer the user's query. |
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