instruction stringlengths 142 1.1k | input stringlengths 255 1.83k | response stringclasses 11 values |
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<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
B: icsbp (mus musculus) (aka interferon regulatory factor 8)
C: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
D: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
E: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
F: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
G: icsbp1 (xenopus laevis) (interferon regulatory factor 8 s homeolog (xenopus laevis)) (aka interferon regulatory factor 8 s homeolog)
H: interferon regulatory factor 6, gene 2 s homeolog (xenopus laevis) (aka interferon regulatory factor 6, gene 2 s homeolog)
I: ilbp (homo sapiens) (aka fatty acid binding protein 6)
J: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
K: None of the above. | B |
<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept corresponding to 'type i interferon'. Answer using one of the provided options. | <Options>: A: ifn-alphaa (homo sapiens) (aka interferon alpha 2)
B: infe1 (homo sapiens) (interferon kappa (homo sapiens)) (aka interferon kappa)
C: ifn-e1 (homo sapiens) (aka interferon epsilon)
D: interferon (gallus gallus) (aka interferon)
E: interferon, alpha 1 (rattus norvegicus) (aka interferon, alpha 1)
F: ifn-alpha (homo sapiens) (aka interferon alpha 1)
G: ifn-alphai (homo sapiens) (interferon alpha 17 (homo sapiens)) (aka interferon alpha 17)
H: interferon omega 1 (homo sapiens) (aka interferon omega 1)
I: ifnl1 (homo sapiens) (aka interferon lambda 1)
J: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
K: None of the above. | K |
<Instruct>: Given the context 'ICSBP is essential for the development of mouse type I interferon-producing cells and for the generation and activation of CD8alpha(+) dendritic cells.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8 subunit alpha (canis lupus familiaris) (aka cd8 subunit alpha)
B: cd8 subunit alpha (mus caroli) (aka cd8 subunit alpha)
C: cd8b2 (homo sapiens) (aka cd8b family member 2)
D: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha)
E: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
F: cd8a (homo sapiens) (aka cd8 subunit alpha)
G: cd8 (gallus gallus) (cd8a molecule (gallus gallus)) (aka cd8a molecule)
H: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s homeolog)
I: cd8b (homo sapiens) (aka cd8 subunit beta)
J: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
K: None of the above. | D |
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept corresponding to 'interferon (ifn) consensus sequence-binding protein'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 6 (mus caroli) (aka interferon regulatory factor 6)
B: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
C: interferon regulatory factor 3 (homo sapiens) (aka interferon regulatory factor 3)
D: interferon regulatory factor 4 (homo sapiens) (aka interferon regulatory factor 4)
E: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
F: interferon regulatory factor 8 (mus musculus) (aka interferon regulatory factor 8)
G: interferon regulatory factor 9 (homo sapiens) (aka interferon regulatory factor 9)
H: interferon regulatory factor 7 (homo sapiens) (aka interferon regulatory factor 7)
I: interferon regulatory factor 2 (homo sapiens) (aka interferon regulatory factor 2)
J: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
K: None of the above. | F |
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
B: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
C: icsbp (mus musculus) (aka interferon regulatory factor 8)
D: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
E: interferon regulatory factor 2 binding protein 1 (mus musculus) (aka interferon regulatory factor 2 binding protein 1)
F: h-icsbp (homo sapiens) (aka interferon regulatory factor 8)
G: icsbp1 (sus scrofa) (aka interferon regulatory factor 8)
H: ilbp (homo sapiens) (aka fatty acid binding protein 6)
I: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
J: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
K: None of the above. | C |
<Instruct>: Given the context 'Interferon (IFN) consensus sequence-binding protein (ICSBP) is a transcription factor playing a critical role in the regulation of lineage commitment, especially in myeloid cell differentiation.', select the correct biomedical concept corresponding to 'transcription factor'. Answer using one of the provided options. | <Options>: A: transcription factor ec (xenopus tropicalis) (aka transcription factor ec)
B: transcription factor ec (mus musculus) (aka transcription factor ec)
C: transcription factor ec (gallus gallus) (aka transcription factor ec)
D: tcf-1 (homo sapiens) (hnf1 homeobox a (homo sapiens)) (aka hnf1 homeobox a)
E: transcription factor ec (homo sapiens) (aka transcription factor ec)
F: tcf1 (xenopus tropicalis) (transcription factor 7 (xenopus tropicalis)) (aka transcription factor 7)
G: transcription factor 4 (danio rerio) (tcf4 (danio rerio)) (aka transcription factor 4)
H: transcription factor 3 (homo sapiens) (aka transcription factor 3)
I: tcf4 (xenopus tropicalis) (transcription factor 4 (xenopus tropicalis)) (aka transcription factor 4)
J: transcription factor 4 (homo sapiens) (aka transcription factor 4)
K: None of the above. | K |
<Instruct>: Given the context 'In this study, we have characterized the phenotype and activation pattern of subsets of dendritic cells (DCs) in ICSBP(-/-) mice.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp (homo sapiens) (aka interferon regulatory factor 8)
B: icsbp (mus musculus) (aka interferon regulatory factor 8)
C: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
D: interferon regulatory factor 2 binding protein 1 (mus musculus) (aka interferon regulatory factor 2 binding protein 1)
E: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
F: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
G: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
H: icsbp1 (xenopus laevis) (interferon regulatory factor 8 s homeolog (xenopus laevis)) (aka interferon regulatory factor 8 s homeolog)
I: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
J: interferon regulatory factor 5 (canis lupus familiaris) (aka interferon regulatory factor 5)
K: None of the above. | B |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'ifn'. Answer using one of the provided options. | <Options>: A: ifnan (homo sapiens) (aka interferon lambda 4 (gene/pseudogene))
B: inf (homo sapiens) (aka cobalamin binding intrinsic factor)
C: ifnb (homo sapiens) (aka interferon beta 1)
D: ifna (homo sapiens) (interferon, type 1, cluster (homo sapiens)) (aka interferon, type 1, cluster)
E: ifn (xenopus laevis) (uncharacterized loc108702184 (xenopus laevis)) (aka uncharacterized loc108702184)
F: ifna1 (homo sapiens) (aka interferon alpha 1)
G: ifn-alphah (homo sapiens) (aka interferon alpha 14)
H: infe1 (homo sapiens) (interferon kappa (homo sapiens)) (aka interferon kappa)
I: ifn-alphao (homo sapiens) (aka interferon alpha 16)
J: ifn-e1 (homo sapiens) (aka interferon epsilon)
K: None of the above. | K |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
B: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
C: icsbp1 (sus scrofa) (aka interferon regulatory factor 8)
D: icsbp1 (mus musculus) (aka interferon regulatory factor 8)
E: interferon regulatory factor 6, gene 2 s homeolog (xenopus laevis) (aka interferon regulatory factor 6, gene 2 s homeolog)
F: icsbp1 (xenopus laevis) (interferon regulatory factor 8 s homeolog (xenopus laevis)) (aka interferon regulatory factor 8 s homeolog)
G: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
H: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
I: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
J: interferon regulatory factor 5 (canis lupus familiaris) (aka interferon regulatory factor 5)
K: None of the above. | D |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'cd11c'. Answer using one of the provided options. | <Options>: A: orphan cd11c (drosophila melanogaster) (aka ncrna)
B: cd11c (homo sapiens) (aka integrin subunit alpha x)
C: leukocyte receptor cluster member 1 (homo sapiens) (aka leukocyte receptor cluster member 1)
D: itgax (canis lupus familiaris) (aka integrin subunit alpha x)
E: cd11b (homo sapiens) (aka integrin subunit alpha m)
F: itgax (mus musculus) (aka integrin alpha x)
G: cd103 (homo sapiens) (aka integrin subunit alpha e)
H: leu1 (homo sapiens) (cd5 molecule (homo sapiens)) (aka cd5 molecule)
I: alpha7 (mus musculus) (integrin alpha 7 (mus musculus)) (aka integrin alpha 7)
J: cd1a (homo sapiens) (cd1e molecule (homo sapiens)) (aka cd1e molecule)
K: None of the above. | F |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'b220'. Answer using one of the provided options. | <Options>: A: cd45-ap (homo sapiens) (aka protein tyrosine phosphatase receptor type c associated protein)
B: protein tyrosine phosphatase, receptor type a (gallus gallus) (aka protein tyrosine phosphatase, receptor type a)
C: mb1 (homo sapiens) (cd79a molecule (homo sapiens)) (aka cd79a molecule)
D: cd45 (mus musculus) (aka protein tyrosine phosphatase receptor type c)
E: cd79a antigen (immunoglobulin-associated alpha) (mus musculus) (aka cd79a antigen (immunoglobulin-associated alpha))
F: protein tyrosine phosphatase, receptor type b (gallus gallus) (aka protein tyrosine phosphatase, receptor type b)
G: cd45 (xenopus laevis) (protein tyrosine phosphatase, receptor type c l homeolog (xenopus laevis)) (aka protein tyrosine phosphatase, receptor type c l homeolog)
H: cd45 (xenopus laevis) (protein tyrosine phosphatase, receptor type c s homeolog (xenopus laevis)) (aka protein tyrosine phosphatase, receptor type c s homeolog)
I: protein tyrosine phosphatase receptor type a (homo sapiens) (aka protein tyrosine phosphatase receptor type a)
J: cd45 (rattus norvegicus) (aka protein tyrosine phosphatase, receptor type, c)
K: None of the above. | D |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'ly6c'. Answer using one of the provided options. | <Options>: A: ly6c (mus musculus) (aka lymphocyte antigen 6 family member c1)
B: ly6s (homo sapiens) (aka lymphocyte antigen 6 family member s)
C: ly6d (homo sapiens) (aka lymphocyte antigen 6 family member d)
D: ly6c2 (mus musculus) (aka lymphocyte antigen 6 family memberc2)
E: ly6l (mus musculus) (aka lymphocyte antigen 6 family member l)
F: ly6k (homo sapiens) (aka lymphocyte antigen 6 family member k)
G: ly6h (homo sapiens) (aka lymphocyte antigen 6 family member h)
H: ly6e (homo sapiens) (aka lymphocyte antigen 6 family member e)
I: ly6f (mus musculus) (aka lymphocyte antigen 6 family member f)
J: ly6i (mus musculus) (aka lymphocyte antigen 6 family member i)
K: None of the above. | A |
<Instruct>: Given the context 'Remarkably, the recently identified mouse IFN-producing cells (mIPCs) were absent in all lymphoid organs from ICSBP(-/-) mice, as revealed by lack of CD11c(low)B220(+)Ly6C(+)CD11b(-) cells.', select the correct biomedical concept corresponding to 'cd11b'. Answer using one of the provided options. | <Options>: A: cd11b (gallus gallus) (aka integrin, alpha d)
B: cd11b (bos taurus) (aka integrin subunit alpha m)
C: integrin alpha l (mus musculus) (aka integrin alpha l)
D: integrin subunit alpha l (homo sapiens) (aka integrin subunit alpha l)
E: mac-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
F: mo1a (homo sapiens) (aka integrin subunit alpha m)
G: integrin alpha 4 (mus musculus) (aka integrin alpha 4)
H: integrin alpha m (mus musculus) (aka integrin alpha m)
I: integrin alpha 3 (mus musculus) (aka integrin alpha 3)
J: itga7 (homo sapiens) (aka integrin subunit alpha 7)
K: None of the above. | H |
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept corresponding to 'cd11c'. Answer using one of the provided options. | <Options>: A: alpha7 (mus musculus) (integrin alpha 7 (mus musculus)) (aka integrin alpha 7)
B: itgax (mus musculus) (aka integrin alpha x)
C: cd103 (homo sapiens) (aka integrin subunit alpha e)
D: cd11a (mus musculus) (aka integrin alpha l)
E: cd1c (homo sapiens) (aka cd1c molecule)
F: leu1 (homo sapiens) (cd5 molecule (homo sapiens)) (aka cd5 molecule)
G: integrin subunit alpha x (homo sapiens) (aka integrin subunit alpha x)
H: orphan cd11c (drosophila melanogaster) (aka ncrna)
I: leukocyte receptor cluster member 1 (homo sapiens) (aka leukocyte receptor cluster member 1)
J: cd11a (homo sapiens) (aka integrin subunit alpha l)
K: None of the above. | B |
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
B: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
C: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
D: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
E: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
F: interferon regulatory factor 6, gene 2 s homeolog (xenopus laevis) (aka interferon regulatory factor 6, gene 2 s homeolog)
G: interferon regulatory factor 5 (canis lupus familiaris) (aka interferon regulatory factor 5)
H: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
I: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
J: icsbp (mus musculus) (aka interferon regulatory factor 8)
K: None of the above. | J |
<Instruct>: Given the context 'In parallel, CD11c(+) cells isolated from ICSBP(-/-) spleens were unable to produce type I IFNs in response to viral stimulation.', select the correct biomedical concept corresponding to 'type i ifns'. Answer using one of the provided options. | <Options>: A: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
B: ifn-e1 (homo sapiens) (aka interferon epsilon)
C: ifn-alphai (homo sapiens) (interferon alpha 17 (homo sapiens)) (aka interferon alpha 17)
D: interferon alpha 1 (homo sapiens) (aka interferon alpha 1)
E: interferon omega 1 (homo sapiens) (aka interferon omega 1)
F: ifnl1 (homo sapiens) (aka interferon lambda 1)
G: ifna-j (homo sapiens) (aka interferon alpha 7)
H: ifnai1 (homo sapiens) (aka interferon induced protein with tetratricopeptide repeats 1)
I: ifng (homo sapiens) (aka interferon gamma)
J: ifn-alphaa (homo sapiens) (aka interferon alpha 2)
K: None of the above. | K |
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
B: interferon regulatory factor 5 (canis lupus familiaris) (aka interferon regulatory factor 5)
C: icsbp1 (xenopus laevis) (interferon regulatory factor 8 s homeolog (xenopus laevis)) (aka interferon regulatory factor 8 s homeolog)
D: interferon regulatory factor 6, gene 2 s homeolog (xenopus laevis) (aka interferon regulatory factor 6, gene 2 s homeolog)
E: icsbp (mus musculus) (aka interferon regulatory factor 8)
F: h-icsbp (homo sapiens) (aka interferon regulatory factor 8)
G: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
H: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
I: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
J: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
K: None of the above. | E |
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
B: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s homeolog)
C: cd8 (gallus gallus) (cd8a molecule (gallus gallus)) (aka cd8a molecule)
D: cd8beta (homo sapiens) (aka cd8 subunit beta)
E: cd8 subunit alpha (canis lupus familiaris) (aka cd8 subunit alpha)
F: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha)
G: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
H: cd8b2 (homo sapiens) (aka cd8b family member 2)
I: cd8 subunit alpha (mus caroli) (aka cd8 subunit alpha)
J: leu2 (homo sapiens) (cd8 subunit alpha (homo sapiens)) (aka cd8 subunit alpha)
K: None of the above. | F |
<Instruct>: Given the context 'ICSBP(-/-) mice also displayed a marked reduction of the DC subset expressing the CD8alpha marker (CD8alpha(+) DCs) in spleen, lymph nodes, and thymus.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
B: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s homeolog)
C: cd8b family member 2 (homo sapiens) (aka cd8b family member 2)
D: cd8alpha (homo sapiens) (aka cd8 subunit alpha)
E: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
F: cd8 (gallus gallus) (cd8a molecule (gallus gallus)) (aka cd8a molecule)
G: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta)
H: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha)
I: cd8 subunit alpha (canis lupus familiaris) (aka cd8 subunit alpha)
J: cd8 subunit alpha (mus caroli) (aka cd8 subunit alpha)
K: None of the above. | H |
<Instruct>: Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
B: icsbp (mus musculus) (aka interferon regulatory factor 8)
C: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
D: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
E: ilbp (homo sapiens) (aka fatty acid binding protein 6)
F: icsbp1 (xenopus laevis) (interferon regulatory factor 8 s homeolog (xenopus laevis)) (aka interferon regulatory factor 8 s homeolog)
G: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
H: icsbp1 (sus scrofa) (aka interferon regulatory factor 8)
I: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
J: interferon regulatory factor 6, gene 2 s homeolog (xenopus laevis) (aka interferon regulatory factor 6, gene 2 s homeolog)
K: None of the above. | B |
<Instruct>: Given the context 'Moreover, ICSBP(-/-) CD8alpha(+) DCs exhibited a markedly impaired phenotype when compared with WT DCs.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8b1 (homo sapiens) (aka cd8 subunit beta)
B: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
C: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
D: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s homeolog)
E: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha)
F: cd8b family member 2 (homo sapiens) (aka cd8b family member 2)
G: cd8 subunit alpha (mus caroli) (aka cd8 subunit alpha)
H: cd8 subunit alpha (canis lupus familiaris) (aka cd8 subunit alpha)
I: cd8 (gallus gallus) (cd8a molecule (gallus gallus)) (aka cd8a molecule)
J: cd8alpha (homo sapiens) (aka cd8 subunit alpha)
K: None of the above. | E |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept corresponding to 'intercellular adhesion molecule [icam]-1'. Answer using one of the provided options. | <Options>: A: icam-1 (canis lupus familiaris) (aka intercellular adhesion molecule 1)
B: intercellular adhesion molecule 1 (mus musculus) (aka intercellular adhesion molecule 1)
C: intercellular adhesion molecule 3 (homo sapiens) (aka intercellular adhesion molecule 3)
D: icam-4 (mus musculus) (aka intercellular adhesion molecule 4, landsteiner-wiener blood group)
E: icam4 (homo sapiens) (aka intercellular adhesion molecule 4 (landsteiner-wiener blood group))
F: icam-3 (mus musculus) (aka intercellular adhesion molecule 5, telencephalin)
G: intercellular adhesion molecule 1, related sequence 1 (mus musculus) (aka intercellular adhesion molecule 1, related sequence 1)
H: icam1 (oryctolagus cuniculus) (intercellular adhesion molecule 1 (oryctolagus cuniculus)) (aka intercellular adhesion molecule 1)
I: intercellular adhesion molecule 2 (homo sapiens) (aka intercellular adhesion molecule 2)
J: icam1 (oryctolagus cuniculus) (intercellular adhesion molecule-1 (oryctolagus cuniculus)) (aka intercellular adhesion molecule-1)
K: None of the above. | B |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept corresponding to 'cd40'. Answer using one of the provided options. | <Options>: A: cd40 (canis lupus familiaris) (aka cd40 molecule)
B: cd40l (homo sapiens) (aka cd40 ligand)
C: tnf receptor superfamily member 4 (homo sapiens) (aka tnf receptor superfamily member 4)
D: cd40 molecule (homo sapiens) (aka cd40 molecule)
E: p50 (mus musculus) (cd40 antigen (mus musculus)) (aka cd40 antigen)
F: cd40 (bos taurus) (aka cd40 molecule)
G: cd40 molecule (cricetulus griseus) (aka cd40 molecule)
H: cd40 (gallus gallus) (aka cd40 molecule)
I: cd40 (oryctolagus cuniculus) (aka cd40 molecule)
J: None of the above. | E |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept corresponding to 'cd80'. Answer using one of the provided options. | <Options>: A: cd80 molecule l homeolog (xenopus laevis) (aka cd80 molecule l homeolog)
B: b7 (mus musculus) (cd86 antigen (mus musculus)) (aka cd86 antigen)
C: cd80 molecule (canis lupus familiaris) (aka cd80 molecule)
D: cd80 (oryctolagus cuniculus) (aka cd80 molecule)
E: bb1 (homo sapiens) (cd80 molecule (homo sapiens)) (aka cd80 molecule)
F: cd80 molecule (rattus norvegicus) (aka cd80 molecule)
G: cd86 molecule (homo sapiens) (aka cd86 molecule)
H: cd80 (gallus gallus) (aka cd88 molecule)
I: cd80 (sus scrofa) (aka cd80 molecule)
J: cd80 antigen (mus musculus) (aka cd80 antigen)
K: None of the above. | J |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept corresponding to 'cd86'. Answer using one of the provided options. | <Options>: A: t-lymphocyte activation antigen cd86 l homeolog (xenopus laevis) (aka t-lymphocyte activation antigen cd86 l homeolog)
B: cd86 antigen (mus musculus) (aka cd86 antigen)
C: bb1 (homo sapiens) (cd80 molecule (homo sapiens)) (aka cd80 molecule)
D: cd86 molecule (homo sapiens) (aka cd86 molecule)
E: cd86 molecule (gallus gallus) (aka cd86 molecule)
F: cd86 molecule (mus caroli) (aka cd86 molecule)
G: cd86 (canis lupus familiaris) (aka cd86 molecule)
H: cd86 molecule (rattus norvegicus) (aka cd86 molecule)
I: cd86 molecule (bos taurus) (aka cd86 molecule)
J: cd86 molecule (sus scrofa) (aka cd86 molecule)
K: None of the above. | B |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept corresponding to 'ccr7'. Answer using one of the provided options. | <Options>: A: ccr7 (mus musculus) (aka c-c motif chemokine receptor 7)
B: c-c motif chemokine receptor 7 (xenopus tropicalis) (aka c-c motif chemokine receptor 7)
C: cd191 (homo sapiens) (aka c-c motif chemokine receptor 1)
D: c-c motif chemokine receptor 7 (bos taurus) (aka c-c motif chemokine receptor 7)
E: c-c motif chemokine receptor 7 s homeolog (xenopus laevis) (aka c-c motif chemokine receptor 7 s homeolog)
F: ccr7 (sus scrofa) (aka c-c motif chemokine receptor 7)
G: c-c motif chemokine receptor 7 l homeolog (xenopus laevis) (aka c-c motif chemokine receptor 7 l homeolog)
H: c-c chemokine receptor type 1-like (bos taurus) (aka c-c chemokine receptor type 1-like)
I: ccr7 (canis lupus familiaris) (aka c-c motif chemokine receptor 7)
J: cd192 (homo sapiens) (aka c-c motif chemokine receptor 2)
K: None of the above. | A |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept corresponding to 'ccr2'. Answer using one of the provided options. | <Options>: A: ccbp2 (homo sapiens) (atypical chemokine receptor 2 (homo sapiens)) (aka atypical chemokine receptor 2)
B: cc-ckr-2 (xenopus laevis) (chemokine (c-c motif) receptor 2 l homeolog (xenopus laevis)) (aka chemokine (c-c motif) receptor 2 l homeolog)
C: c-c motif chemokine receptor-like 2 (mus musculus) (aka c-c motif chemokine receptor-like 2)
D: c-c motif chemokine receptor 2 (mus musculus) (aka c-c motif chemokine receptor 2)
E: mcp-1-r (xenopus laevis) (chemokine (c-c motif) receptor 2 s homeolog (xenopus laevis)) (aka chemokine (c-c motif) receptor 2 s homeolog)
F: hcr (homo sapiens) (c-c motif chemokine receptor like 2 (homo sapiens)) (aka c-c motif chemokine receptor like 2)
G: c-c motif chemokine receptor 2 (homo sapiens) (aka c-c motif chemokine receptor 2)
H: None of the above. | D |
<Instruct>: Given the context 'They expressed very low levels of costimulatory molecules (intercellular adhesion molecule [ICAM]-1, CD40, CD80, CD86) and of the T cell area-homing chemokine receptor CCR7, whereas they showed higher levels of CCR2 and CCR6, as revealed by reverse transcription PCR.', select the correct biomedical concept corresponding to 'ccr6'. Answer using one of the provided options. | <Options>: A: ccr3 (homo sapiens) (aka c-c motif chemokine receptor 3)
B: c-c motif chemokine receptor 6 (homo sapiens) (aka c-c motif chemokine receptor 6)
C: ccr-2a (homo sapiens) (aka c-c motif chemokine receptor 2)
D: ccr10 (homo sapiens) (c-c motif chemokine receptor 10 (homo sapiens)) (aka c-c motif chemokine receptor 10)
E: ccr-5 (homo sapiens) (aka c-c motif chemokine receptor 5)
F: cc-ckr-6 (mus musculus) (aka c-c motif chemokine receptor 6)
G: ccr10 (homo sapiens) (atypical chemokine receptor 2 (homo sapiens)) (aka atypical chemokine receptor 2)
H: ccr9 (mus musculus) (atypical chemokine receptor 2 (mus musculus)) (aka atypical chemokine receptor 2)
I: ccr10 (homo sapiens) (atypical chemokine receptor 4 (homo sapiens)) (aka atypical chemokine receptor 4)
J: ccr-8 (homo sapiens) (aka c-c motif chemokine receptor 8)
K: None of the above. | F |
<Instruct>: Given the context 'In addition, these cells were unable to undergo full phenotypic activation upon in vitro culture in presence of maturation stimuli such as lipopolysaccharide or poly (I:C), which paralleled with lack of Toll-like receptor (TLR)3 mRNA expression.', select the correct biomedical concept corresponding to 'toll-like receptor (tlr)3'. Answer using one of the provided options. | <Options>: A: toll like receptor 3 (xenopus tropicalis) (aka toll like receptor 3)
B: toll3 (drosophila melanogaster) (aka mstprox)
C: toll like receptor 7 (homo sapiens) (aka toll like receptor 7)
D: toll like receptor 3 (canis lupus familiaris) (aka toll like receptor 3)
E: toll like receptor 3 (bos taurus) (aka toll like receptor 3)
F: toll-like receptor 3 (mus musculus) (aka toll-like receptor 3)
G: tlr6 (homo sapiens) (aka toll like receptor 6)
H: toll like receptor 4 (homo sapiens) (aka toll like receptor 4)
I: tlr5 (homo sapiens) (aka toll like receptor 5)
J: toll like receptor 8 (homo sapiens) (aka toll like receptor 8)
K: None of the above. | F |
<Instruct>: Given the context 'Finally, cytokine expression pattern was also altered in ICSBP(-/-)', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp1 (mus musculus) (aka interferon regulatory factor 8)
B: interferon regulatory factor 6, gene 2 s homeolog (xenopus laevis) (aka interferon regulatory factor 6, gene 2 s homeolog)
C: interferon regulatory factor 5 (canis lupus familiaris) (aka interferon regulatory factor 5)
D: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
E: icsbp1 (sus scrofa) (aka interferon regulatory factor 8)
F: icsbp (homo sapiens) (aka interferon regulatory factor 8)
G: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
H: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
I: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
J: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
K: None of the above. | A |
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept corresponding to 'interleukin (il)-12p40'. Answer using one of the provided options. | <Options>: A: interleukin 12a (canis lupus familiaris) (aka interleukin 12a)
B: p40 (mus musculus) (interleukin 12b (mus musculus)) (aka interleukin 12b)
C: p600 (homo sapiens) (interleukin 13 (homo sapiens)) (aka interleukin 13)
D: p40 (mus musculus) (interleukin 9 (mus musculus)) (aka interleukin 9)
E: p40 (homo sapiens) (interleukin 9 (homo sapiens)) (aka interleukin 9)
F: interleukin 12b (canis lupus familiaris) (aka interleukin 12b)
G: il-40 (homo sapiens) (aka chromosome 17 open reading frame 99)
H: p35 (xenopus laevis) (interleukin 12 subunit alpha l homeolog (xenopus laevis)) (aka interleukin 12 subunit alpha l homeolog)
I: interleukin 12a (homo sapiens) (aka interleukin 12a)
J: il-12b (homo sapiens) (aka interleukin 12b)
K: None of the above. | B |
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept corresponding to 'il-15'. Answer using one of the provided options. | <Options>: A: interleukin-15 (gallus gallus) (aka interleukin 15)
B: interleukin 15-like (ovis aries) (aka interleukin 15-like)
C: interleukin 15 (ovis aries) (aka interleukin 15)
D: il-15 (xenopus laevis) (interleukin 15 s homeolog (xenopus laevis)) (aka interleukin 15 s homeolog)
E: il-15 (xenopus laevis) (interleukin 15 l homeolog (xenopus laevis)) (aka interleukin 15 l homeolog)
F: interleukin 15-like (oryctolagus cuniculus) (aka interleukin 15-like)
G: il-15 (mus musculus) (aka interleukin 15)
H: interleukin 15 (cricetulus griseus) (aka interleukin 15)
I: interleukin-15-like (canis lupus familiaris) (aka interleukin-15-like)
J: interleukin 15 (rattus norvegicus) (aka interleukin 15)
K: None of the above. | G |
<Instruct>: Given the context 'DCs, as they did not express interleukin (IL)-12p40 or IL-15, but they displayed detectable IL-4 mRNA levels.', select the correct biomedical concept corresponding to 'il-4'. Answer using one of the provided options. | <Options>: A: interleukin 4 (gallus gallus) (aka interleukin 4)
B: il-4 (mus musculus) (aka interleukin 4)
C: interleukin 5 (homo sapiens) (aka interleukin 5)
D: il4 (canis lupus familiaris) (aka interleukin 4)
E: interleukin 4 (cricetulus griseus) (aka interleukin 4)
F: il-4 (homo sapiens) (aka interleukin 4)
G: interleukin 4 (oryctolagus cuniculus) (aka interleukin 4)
H: interleukin 4 (rattus norvegicus) (aka interleukin 4)
I: il-4 (bos taurus) (aka interleukin 4)
J: interleukin 4 (ovis aries) (aka interleukin 4)
K: None of the above. | B |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: icsbp1 (mus musculus) (aka interferon regulatory factor 8)
B: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
C: icsbp1 (sus scrofa) (aka interferon regulatory factor 8)
D: ilbp (homo sapiens) (aka fatty acid binding protein 6)
E: icsbp (homo sapiens) (aka interferon regulatory factor 8)
F: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
G: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
H: interferon regulatory factor 2 binding protein 1 (mus musculus) (aka interferon regulatory factor 2 binding protein 1)
I: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
J: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
K: None of the above. | A |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: h-icsbp (homo sapiens) (aka interferon regulatory factor 8)
B: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
C: interferon regulatory factor 2 binding protein 1 (canis lupus familiaris) (aka interferon regulatory factor 2 binding protein 1)
D: interferon regulatory factor 2 binding protein 1 (homo sapiens) (aka interferon regulatory factor 2 binding protein 1)
E: icsbp (mus musculus) (aka interferon regulatory factor 8)
F: interferon regulatory factor 2 binding protein 1 (mus musculus) (aka interferon regulatory factor 2 binding protein 1)
G: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
H: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
I: ilbp (homo sapiens) (aka fatty acid binding protein 6)
J: interferon regulatory factor 8 s homeolog (xenopus laevis) (aka interferon regulatory factor 8 s homeolog)
K: None of the above. | E |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', select the correct biomedical concept corresponding to 'cd8alpha'. Answer using one of the provided options. | <Options>: A: cd8 subunit alpha (canis lupus familiaris) (aka cd8 subunit alpha)
B: cd8 (gallus gallus) (cd8a molecule (gallus gallus)) (aka cd8a molecule)
C: cd8 (xenopus laevis) (cd8 subunit alpha l homeolog (xenopus laevis)) (aka cd8 subunit alpha l homeolog)
D: cd8 subunit alpha (mus musculus) (aka cd8 subunit alpha)
E: cd8 subunit beta (homo sapiens) (aka cd8 subunit beta)
F: cd8 (xenopus laevis) (cd8 subunit alpha s homeolog (xenopus laevis)) (aka cd8 subunit alpha s homeolog)
G: cd8 subunit alpha (mus caroli) (aka cd8 subunit alpha)
H: cd8b2 (homo sapiens) (aka cd8b family member 2)
I: cd8alpha (homo sapiens) (aka cd8 subunit alpha)
J: cd8 subunit alpha (sus scrofa) (aka cd8 subunit alpha)
K: None of the above. | D |
<Instruct>: Given the context 'On the whole, these results indicate that ICSBP is a crucial factor in the regulation of two possibly linked processes: (a) the development and activity of mIPCs, whose lack in ICSBP(-/-) mice may explain their high susceptibility to virus infections; (b) the generation and activation of CD8alpha(+) DCs, whose impairment in ICSBP(-/-) mice can be responsible for the defective generation of a Th1 type of immune response.', select the correct biomedical concept corresponding to 'icsbp'. Answer using one of the provided options. | <Options>: A: interferon regulatory factor 6 (homo sapiens) (aka interferon regulatory factor 6)
B: interferon regulatory factor 5 (homo sapiens) (aka interferon regulatory factor 5)
C: icsbp1 (xenopus tropicalis) (aka interferon regulatory factor 8)
D: icsbp1 (xenopus laevis) (interferon regulatory factor 8 l homeolog (xenopus laevis)) (aka interferon regulatory factor 8 l homeolog)
E: ics1 (homo sapiens) (aka dynein axonemal intermediate chain 1)
F: interferon regulatory factor 1 (homo sapiens) (aka interferon regulatory factor 1)
G: icsbp (mus musculus) (aka interferon regulatory factor 8)
H: icsbp1 (homo sapiens) (aka interferon regulatory factor 8)
I: interferon regulatory factor 2 binding protein 1 (mus musculus) (aka interferon regulatory factor 2 binding protein 1)
J: icsbp1 (xenopus laevis) (interferon regulatory factor 8 s homeolog (xenopus laevis)) (aka interferon regulatory factor 8 s homeolog)
K: None of the above. | G |
<Instruct>: Given the context 'Sarco(endo)plasmic reticulum Ca2+-ATPase-2 gene: structure and transcriptional regulation of the human gene.', select the correct biomedical concept corresponding to 'sarco(endo)plasmic reticulum ca2+-atpase-2'. Answer using one of the provided options. | <Options>: A: dd (homo sapiens) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2 (homo sapiens)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
B: atp2b (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
C: atp2a1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog)
D: atpase secretory pathway ca2+ transporting 2 (homo sapiens) (aka atpase secretory pathway ca2+ transporting 2)
E: atp2b2 (xenopus laevis) (atpase plasma membrane ca2+ transporting 2 s homeolog (xenopus laevis)) (aka atpase plasma membrane ca2+ transporting 2 s homeolog)
F: atpase, ca++ transporting, plasma membrane 2 (mus musculus) (aka atpase, ca++ transporting, plasma membrane 2)
G: atp2b2 (homo sapiens) (atpase plasma membrane ca2+ transporting 4 (homo sapiens)) (aka atpase plasma membrane ca2+ transporting 4)
H: atp2a2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 s homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1 s homeolog)
I: atpase plasma membrane ca2+ transporting 2 (homo sapiens) (aka atpase plasma membrane ca2+ transporting 2)
J: atpase na+/k+ transporting subunit alpha 2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
K: None of the above. | A |
<Instruct>: Given the context 'The sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) belong to a family of active calcium transport enzymes encoded by the SERCA1, 2, and 3 genes.', select the correct biomedical concept corresponding to 'serca1, 2, and 3'. Answer using one of the provided options. | <Options>: A: serca2a (drosophila melanogaster) (aka sarco/endoplasmic reticulum ca(2+)-atpase)
B: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
C: serca1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog)
D: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
E: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
F: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
G: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
H: serca3 (xenopus laevis) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 l homeolog (xenopus laevis)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 l homeolog)
I: serca1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 s homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1 s homeolog)
J: serca2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog)
K: None of the above. | B |
<Instruct>: Given the context 'In this study, we describe the complete structure of the human SERCA2 gene and its 5 -regulatory region.', select the correct biomedical concept corresponding to 'serca2'. Answer using one of the provided options. | <Options>: A: serca2 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
B: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
C: serca2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 l homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2 l homeolog)
D: serca2a (canis lupus familiaris) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
E: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b)
F: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
G: serca2a (drosophila melanogaster) (aka sarco/endoplasmic reticulum ca(2+)-atpase)
H: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
I: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
J: serca3 (xenopus laevis) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog (xenopus laevis)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog)
K: None of the above. | H |
<Instruct>: Given the context 'The hSERCA2 gene is located in chromosome 12 position q24.1 in Contig NT_009770.8, spans 70 kb, and is organized in 21 exons intervened by 20 introns.', select the correct biomedical concept corresponding to 'hserca2'. Answer using one of the provided options. | <Options>: A: cest-2.2 (caenorhabditis elegans) (aka carboxylesterase type b domain-containing protein)
B: establishment of sister chromatid cohesion n-acetyltransferase 2 (homo sapiens) (aka establishment of sister chromatid cohesion n-acetyltransferase 2)
C: ce-a2 (drosophila melanogaster) (aka cecropin a2)
D: tcea2 (homo sapiens) (aka transcription elongation factor a2)
E: carboxylesterase 2 (homo sapiens) (aka carboxylesterase 2)
F: ece-2 (homo sapiens) (aka eef1akmt4-ece2 readthrough)
G: ces2 (xenopus tropicalis) (carboxylesterase 2 gene 1 (xenopus tropicalis)) (aka carboxylesterase 2 gene 1)
H: erda2 (homo sapiens) (aka zinc finger protein 384)
I: ces2 (mus musculus) (carboxylesterase 2h (mus musculus)) (aka carboxylesterase 2h)
J: ces2-like (xenopus tropicalis) (aka carboxylesterase 2 gene 3)
K: None of the above. | K |
<Instruct>: Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', select the correct biomedical concept corresponding to 'serca2a'. Answer using one of the provided options. | <Options>: A: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
B: serca2b (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
C: serca3 (xenopus laevis) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog (xenopus laevis)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog)
D: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
E: serca3b (mus musculus) (aka atpase, ca++ transporting, ubiquitous)
F: serca2a (drosophila melanogaster) (aka sarco/endoplasmic reticulum ca(2+)-atpase)
G: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
H: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
I: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
J: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
K: None of the above. | G |
<Instruct>: Given the context 'The last two exons of the pre-mRNA produce by alternatively splicing the cardiac/slow-twitch muscle-specific SERCA2a isoform and the ubiquitous SERCA2b isoform.', select the correct biomedical concept corresponding to 'serca2b'. Answer using one of the provided options. | <Options>: A: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b)
B: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
C: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
D: serca2 (sus scrofa) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
E: serca1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog)
F: serca2b (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
G: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
H: serca1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 s homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1 s homeolog)
I: serca3 (xenopus laevis) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog (xenopus laevis)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog)
J: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
K: None of the above. | G |
<Instruct>: Given the context 'The sequence of the proximal 225-bp regulatory region of the SERCA2 genes is 80% G+C-rich and is conserved among human, rabbit, rat, and mouse species.', select the correct biomedical concept corresponding to 'serca2'. Answer using one of the provided options. | <Options>: A: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
B: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
C: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
D: serca2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog)
E: serca2a (canis lupus familiaris) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
F: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b)
G: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
H: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
I: serca2a (drosophila melanogaster) (aka sarco/endoplasmic reticulum ca(2+)-atpase)
J: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
K: None of the above. | C |
<Instruct>: Given the context 'It contains a TATA-like-box, an E-box/USF sequence, a CAAT-box, four Sp1 binding sites, and a thyroid hormone responsive element (TRE).', select the correct biomedical concept corresponding to 'sp1'. Answer using one of the provided options. | <Options>: A: sp1 transcription factor (xenopus tropicalis) (aka sp1 transcription factor)
B: sp1-like factor for pairing sensitive-silencing (drosophila melanogaster) (aka sp1-like factor for pairing sensitive-silencing)
C: sp1 transcription factor s homeolog (xenopus laevis) (aka sp1 transcription factor s homeolog)
D: sp17-1 (homo sapiens) (aka sperm autoantigenic protein 17)
E: sp1-like 1 (arabidopsis thaliana) (aka e3 ubiquitin ligase family protein)
F: h-sp1 (homo sapiens) (aka synaptophysin like 1)
G: sp1 (mus musculus) (aka trans-acting transcription factor 1)
H: c-sp1 (drosophila melanogaster) (aka gram-positive specific serine protease)
I: sp1 (homo sapiens) (sp1 transcription factor (homo sapiens)) (aka sp1 transcription factor)
J: d-sp1 (drosophila melanogaster) (aka sp1)
K: None of the above. | I |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'gata-4, -5, -6'. Answer using one of the provided options. | <Options>: A: gata binding protein 4 (homo sapiens) (aka gata binding protein 4)
B: gata6 (xenopus laevis) (gata binding protein 6 s homeolog (xenopus laevis)) (aka gata binding protein 6 s homeolog)
C: gata binding protein 4 (mus musculus) (aka gata binding protein 4)
D: gata binding protein 4 (xenopus tropicalis) (aka gata binding protein 4)
E: gata-3 (xenopus laevis) (gata binding protein 3 l homeolog (xenopus laevis)) (aka gata binding protein 3 l homeolog)
F: gata-c (drosophila melanogaster) (aka grain)
G: gata-4 (xenopus laevis) (gata binding protein 4 s homeolog (xenopus laevis)) (aka gata binding protein 4 s homeolog)
H: gata6 (homo sapiens) (aka gata binding protein 6)
I: gata-5 (xenopus laevis) (gata binding protein 5 l homeolog (xenopus laevis)) (aka gata binding protein 5 l homeolog)
J: gata-4a (xenopus laevis) (gata binding protein 5 s homeolog (xenopus laevis)) (aka gata binding protein 5 s homeolog)
K: None of the above. | K |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'nkx-2.5'. Answer using one of the provided options. | <Options>: A: nkx-2.5 (xenopus laevis) (nk2 homeobox 5 l homeolog (xenopus laevis)) (aka nk2 homeobox 5 l homeolog)
B: nkx-2.5 (xenopus tropicalis) (aka nk2 homeobox 5)
C: nkx-2.3b (xenopus laevis) (aka nk2 homeobox 3 l homeolog)
D: nkx-1.2 (mus musculus) (aka nk1 homeobox 2)
E: nkx-2.5 (mus musculus) (aka nk2 homeobox 5)
F: nkx-3.1 (mus musculus) (aka nk3 homeobox 1)
G: nkx-5.1 (mus musculus) (aka h6 homeobox 3)
H: nkx-3.2 (mus musculus) (aka nk3 homeobox 2)
I: nkx-5.1-a (xenopus laevis) (aka h6 family homeobox 3 l homeolog)
J: nkx-2.2 (mus musculus) (aka nk2 homeobox 2)
K: None of the above. | E |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'csx'. Answer using one of the provided options. | <Options>: A: csx (mus musculus) (aka nk2 homeobox 5)
B: csl (xenopus laevis) (small muscle protein x-linked l homeolog (xenopus laevis)) (aka small muscle protein x-linked l homeolog)
C: csx2 (homo sapiens) (aka nk2 homeobox 6)
D: csx1-a (xenopus tropicalis) (aka nk2 homeobox 5)
E: csx1 (schizosaccharomyces pombe) (aka rna-binding protein csx1)
F: srx (drosophila melanogaster) (aka sulfiredoxin)
G: csl (mus musculus) (small muscle protein, x-linked (mus musculus)) (aka small muscle protein, x-linked)
H: csx1 (homo sapiens) (aka nk2 homeobox 5)
I: csx3 (homo sapiens) (aka nk2 homeobox 3)
J: cs-1 (drosophila melanogaster) (aka krotzkopf verkehrt)
K: None of the above. | A |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'otf-1'. Answer using one of the provided options. | <Options>: A: otf-6 (mus musculus) (aka pou domain, class 3, transcription factor 1)
B: otf1 (homo sapiens) (aka pou class 2 homeobox 1)
C: otf3 (homo sapiens) (pou class 5 homeobox 1 (homo sapiens)) (aka pou class 5 homeobox 1)
D: pou1f1 (homo sapiens) (aka pou class 1 homeobox 1)
E: otf-7 (mus musculus) (aka pou domain, class 3, transcription factor 2)
F: otf-4 (mus musculus) (aka pou domain, class 5, transcription factor 1)
G: otf-1 (xenopus laevis) (aka pou class 2 homeobox 1 l homeolog)
H: pou domain, class 4, transcription factor 1 (mus musculus) (aka pou domain, class 4, transcription factor 1)
I: otf-9 (mus musculus) (aka pou domain, class 3, transcription factor 4)
J: otf-2 (mus musculus) (aka pou domain, class 2, transcription factor 2)
K: None of the above. | B |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'srf'. Answer using one of the provided options. | <Options>: A: srf (drosophila melanogaster) (surf wings (drosophila melanogaster)) (aka surf wings)
B: serum response factor homolog (caenorhabditis elegans) (aka serum response factor homolog)
C: srf-3 (caenorhabditis elegans) (aka udp-galactose/udp-n-acetylglucosamine transporter srf-3)
D: srf (mus musculus) (aka serum response factor)
E: serum response factor (homo sapiens) (aka serum response factor)
F: srf (drosophila melanogaster) (maroon-like (drosophila melanogaster)) (aka maroon-like)
G: srfx (xenopus laevis) (serum response factor s homeolog (xenopus laevis)) (aka serum response factor s homeolog)
H: serum response factor (xenopus tropicalis) (aka serum response factor)
I: d-srf (drosophila melanogaster) (aka blistered)
J: srf.l (xenopus laevis) (aka serum response factor l homeolog)
K: None of the above. | E |
<Instruct>: Given the context 'Among the DNA cis-elements present in these two regulatory regions there are potential binding sites for: GATA-4, -5, -6, Nkx-2.5/Csx, OTF-1, USF, MEF-2, SRF, PPAR/RXR, AP-2, and TREs.', select the correct biomedical concept corresponding to 'ap-2'. Answer using one of the provided options. | <Options>: A: ap-1/2beta (drosophila melanogaster) (aka adaptor protein complex 1/2, beta subunit)
B: ap2 (drosophila melanogaster) (adaptor protein complex 2, sigma subunit (drosophila melanogaster)) (aka adaptor protein complex 2, sigma subunit)
C: transcription factor ap-2 beta (mus musculus) (aka transcription factor ap-2 beta)
D: transcription factor ap-2, alpha (mus musculus) (aka transcription factor ap-2, alpha)
E: ap2alpha (xenopus laevis) (transcription factor ap-2 alpha s homeolog (xenopus laevis)) (aka transcription factor ap-2 alpha s homeolog)
F: ap2 (xenopus tropicalis) (transcription factor ap-2 alpha (xenopus tropicalis)) (aka transcription factor ap-2 alpha)
G: transcription factor ap-2, gamma (mus musculus) (aka transcription factor ap-2, gamma)
H: transcription factor ap-2 beta (homo sapiens) (aka transcription factor ap-2 beta)
I: transcription factor ap-2 alpha (homo sapiens) (aka transcription factor ap-2 alpha)
J: ap2-b (xenopus laevis) (transcription factor ap-2 beta s homeolog (xenopus laevis)) (aka transcription factor ap-2 beta s homeolog)
K: None of the above. | I |
<Instruct>: Given the context 'Upstream from position -1.5 kb, there is no significant homology among the SERCA2 genes cloned.', select the correct biomedical concept corresponding to 'serca2'. Answer using one of the provided options. | <Options>: A: serca3 (xenopus laevis) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog (xenopus laevis)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog)
B: serca1 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1 l homeolog)
C: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
D: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
E: serca2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 l homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2 l homeolog)
F: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
G: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
H: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b)
I: serca2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2 s homeolog)
J: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
K: None of the above. | D |
<Instruct>: Given the context 'In this study, we report the cloning of 2.4 kb of 5-regulatory region and demonstrate that the proximal promoter region is sufficient for expression in cardiac myocytes, and the region from -225 to -1232 bp contains regulatory DNA elements which down-regulate the expression of the SERCA2 gene in neonatal cardiomyocytes.', select the correct biomedical concept corresponding to 'serca2'. Answer using one of the provided options. | <Options>: A: serca2 (danio rerio) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2b)
B: serca1 (mus musculus) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
C: serca1 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 1)
D: serca2a (drosophila melanogaster) (aka sarco/endoplasmic reticulum ca(2+)-atpase)
E: serca2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
F: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2)
G: serca2 (xenopus laevis) (atpase, ca++ transporting, cardiac muscle, slow twitch 2 l homeolog (xenopus laevis)) (aka atpase, ca++ transporting, cardiac muscle, slow twitch 2 l homeolog)
H: serca3 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3)
I: serca2 (xenopus tropicalis) (atpase, ca++ transporting, cardiac muscle, fast twitch 1 (xenopus tropicalis)) (aka atpase, ca++ transporting, cardiac muscle, fast twitch 1)
J: serca3 (xenopus laevis) (atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog (xenopus laevis)) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 3 s homeolog)
K: None of the above. | E |
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept corresponding to 'nfkappab'. Answer using one of the provided options. | <Options>: A: nfkb-p50 (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog (xenopus laevis)) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog)
B: nfkappab (drosophila melanogaster) (dorsal-related immunity factor (drosophila melanogaster)) (aka dorsal-related immunity factor)
C: nfkappabeta1a (drosophila melanogaster) (aka cactus)
D: p100 (homo sapiens) (nuclear factor kappa b subunit 2 (homo sapiens)) (aka nuclear factor kappa b subunit 2)
E: nfkappab (homo sapiens) (aka nuclear factor kappa b subunit 1)
F: nf-kappabeta (drosophila melanogaster) (aka relish)
G: nuclear factor kappa b subunit 2 pseudogene (homo sapiens) (aka nuclear factor kappa b subunit 2 pseudogene)
H: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
I: rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens) (aka rela proto-oncogene, nf-kb subunit pseudogene)
J: nfkappab (drosophila melanogaster) (dorsal (drosophila melanogaster)) (aka dorsal)
K: None of the above. | E |
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage-1 (homo sapiens) (aka mok protein kinase)
B: rage (canis lupus familiaris) (advanced glycosylation end-product specific receptor (canis lupus familiaris)) (aka advanced glycosylation end-product specific receptor)
C: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
D: rage (sus scrofa) (advanced glycosylation end-product specific receptor (sus scrofa)) (aka advanced glycosylation end-product specific receptor)
E: rage1 (mus musculus) (aka mok protein kinase)
F: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor)
G: ragef2 (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 6)
H: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
I: rage-1 (xenopus laevis) (aka mok protein kinase l homeolog)
J: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
K: None of the above. | J |
<Instruct>: Given the context 'Atherosclerosis is an inflammatory disease in which a perpetuated activation of NFkappaB via the RAGE (receptor for advanced glycation end products)-MAPK signalling pathway may play an important pathogenetic role.', select the correct biomedical concept corresponding to 'receptor for advanced glycation end products'. Answer using one of the provided options. | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: advanced glycosylation end-product specific receptor (cricetulus griseus) (aka advanced glycosylation end-product specific receptor)
C: rage (sus scrofa) (advanced glycosylation end-product specific receptor (sus scrofa)) (aka advanced glycosylation end-product specific receptor)
D: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor)
E: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
F: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
G: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
H: age-r2 (homo sapiens) (aka prkcsh beta subunit of glucosidase ii)
I: rage1 (homo sapiens) (aka mok protein kinase)
J: ager1 (homo sapiens) (aka dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit)
K: None of the above. | G |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
B: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
D: ragef2 (homo sapiens) (aka rap guanine nucleotide exchange factor 6)
E: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor)
F: ragef2 (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 6)
G: rage (xenopus laevis) (aka mok protein kinase l homeolog)
H: rage (homo sapiens) (mok protein kinase (homo sapiens)) (aka mok protein kinase)
I: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
J: rage (sus scrofa) (advanced glycosylation end-product specific receptor (sus scrofa)) (aka advanced glycosylation end-product specific receptor)
K: None of the above. | C |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
B: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
E: s100 calcium binding protein a8 (canis lupus familiaris) (aka s100 calcium binding protein a8)
F: s100a (homo sapiens) (aka s100 calcium binding protein a1)
G: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
H: s100a18 (homo sapiens) (aka hornerin)
I: s100a1l (homo sapiens) (aka sentan, cilia apical structure protein)
J: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
K: None of the above. | B |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
B: s100a9 (canis lupus familiaris) (aka s100 calcium binding protein a9)
C: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
D: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
E: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
F: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
G: s100a (xenopus laevis) (s100 calcium binding protein a1 s homeolog (xenopus laevis)) (aka s100 calcium binding protein a1 s homeolog)
H: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
I: s100a1 (homo sapiens) (aka s100 calcium binding protein a1)
J: s100a9 (gallus gallus) (aka s100 calcium binding protein a12)
K: None of the above. | F |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage1 (xenopus laevis) (aka mok protein kinase l homeolog)
B: ragef2 (homo sapiens) (aka rap guanine nucleotide exchange factor 6)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
D: rage (canis lupus familiaris) (advanced glycosylation end-product specific receptor (canis lupus familiaris)) (aka advanced glycosylation end-product specific receptor)
E: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
F: rage1 (mus musculus) (aka mok protein kinase)
G: rage (gallus gallus) (aka mok protein kinase)
H: rage (sus scrofa) (advanced glycosylation end-product specific receptor (sus scrofa)) (aka advanced glycosylation end-product specific receptor)
I: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
J: rage1 (xenopus tropicalis) (aka mok protein kinase)
K: None of the above. | C |
<Instruct>: Given the context 'As recently S100 proteins have been identified as ligands of RAGE, we sought to determine the effects of the proinflammatory heterodimer of S100A8/S100A9 on the RAGE-NFkappaB mediated induction of proinflammatory gene expression.', select the correct biomedical concept corresponding to 'nfkappab'. Answer using one of the provided options. | <Options>: A: nf-kappa-b (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog (xenopus laevis)) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 s homeolog)
B: nfkappab (drosophila melanogaster) (dorsal (drosophila melanogaster)) (aka dorsal)
C: nf-kappabeta (drosophila melanogaster) (aka relish)
D: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
E: nf-kappab (xenopus laevis) (nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog (xenopus laevis)) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells 1 l homeolog)
F: rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens) (aka rela proto-oncogene, nf-kb subunit pseudogene)
G: nfkappabeta1a (drosophila melanogaster) (aka cactus)
H: p100 (homo sapiens) (nuclear factor kappa b subunit 2 (homo sapiens)) (aka nuclear factor kappa b subunit 2)
I: nf-kappab (homo sapiens) (aka nuclear factor kappa b subunit 1)
J: nuclear factor kappa b subunit 2 pseudogene (homo sapiens) (aka nuclear factor kappa b subunit 2 pseudogene)
K: None of the above. | I |
<Instruct>: Given the context 'Human umbilical vein endothelial cells (HUVEC) were preincubated for 72 h with AGE-albumin or unmodified albumin for control, whereas AGE-albumin induction resulted in an upregulation of RAGE.', select the correct biomedical concept corresponding to 'rage'. Answer using one of the provided options. | <Options>: A: rage (mus musculus) (advanced glycosylation end product-specific receptor (mus musculus)) (aka advanced glycosylation end product-specific receptor)
B: ragef (homo sapiens) (aka rap guanine nucleotide exchange factor 2)
C: rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens)) (aka advanced glycosylation end-product specific receptor)
D: rage (gallus gallus) (aka mok protein kinase)
E: ragef2 (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 6)
F: rage (bos taurus) (advanced glycosylation end-product specific receptor (bos taurus)) (aka advanced glycosylation end-product specific receptor)
G: rage-1 (homo sapiens) (aka mok protein kinase)
H: rage1 (mus musculus) (aka mok protein kinase)
I: rage (canis lupus familiaris) (advanced glycosylation end-product specific receptor (canis lupus familiaris)) (aka advanced glycosylation end-product specific receptor)
J: rage (rattus norvegicus) (advanced glycosylation end product-specific receptor (rattus norvegicus)) (aka advanced glycosylation end product-specific receptor)
K: None of the above. | C |
<Instruct>: Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a18 (homo sapiens) (aka hornerin)
B: s100a (homo sapiens) (aka s100 calcium binding protein a1)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8)
E: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
F: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
G: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
H: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
I: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
J: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
K: None of the above. | D |
<Instruct>: Given the context 'Following this preactivation, cells were stimulated for 48 h with heterodimeric human recombinant S100A8/S100A9.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
B: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
C: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
D: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
E: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
F: s100a7b (homo sapiens) (aka s100 calcium binding protein a7 like 2)
G: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
H: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
I: s100a9 (gallus gallus) (aka s100 calcium binding protein a12)
J: s100a9 (canis lupus familiaris) (aka s100 calcium binding protein a9)
K: None of the above. | A |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
B: s100al (homo sapiens) (aka sentan, cilia apical structure protein)
C: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
D: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
E: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
F: s100a8 (canis lupus familiaris) (aka s100 calcium binding protein a8)
G: s100a18 (homo sapiens) (aka hornerin)
H: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8)
I: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
J: s100a (homo sapiens) (aka s100 calcium binding protein a1)
K: None of the above. | H |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
B: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: s100a9 (canis lupus familiaris) (aka s100 calcium binding protein a9)
E: s100al (homo sapiens) (aka sentan, cilia apical structure protein)
F: s100a11 (homo sapiens) (aka s100 calcium binding protein a11)
G: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
H: s100a7b (homo sapiens) (aka s100 calcium binding protein a7 like 2)
I: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
J: s100a (xenopus laevis) (s100 calcium binding protein a1 s homeolog (xenopus laevis)) (aka s100 calcium binding protein a1 s homeolog)
K: None of the above. | B |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'il-6'. Answer using one of the provided options. | <Options>: A: interleukin 6 (canis lupus familiaris) (aka interleukin 6)
B: interleukin 6 (rattus norvegicus) (aka interleukin 6)
C: interleukin 6 (ovis aries) (aka interleukin 6)
D: cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens)) (aka lif interleukin 6 family cytokine)
E: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
F: hbgf-6 (homo sapiens) (aka fibroblast growth factor 6)
G: interleukin 6 (cricetulus griseus) (aka interleukin 6)
H: interleukin 6 (mus musculus) (aka interleukin 6)
I: il-6 (xenopus laevis) (interleukin 6 l homeolog (xenopus laevis)) (aka interleukin 6 l homeolog)
J: il-6 (gallus gallus) (aka interleukin 6)
K: None of the above. | E |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'icam-1'. Answer using one of the provided options. | <Options>: A: icam1 (oryctolagus cuniculus) (intercellular adhesion molecule-1 (oryctolagus cuniculus)) (aka intercellular adhesion molecule-1)
B: icam-4 (mus musculus) (aka intercellular adhesion molecule 4, landsteiner-wiener blood group)
C: intercellular adhesion molecule 1 (mus musculus) (aka intercellular adhesion molecule 1)
D: icam5 (homo sapiens) (aka intercellular adhesion molecule 5)
E: icam2 (homo sapiens) (aka intercellular adhesion molecule 2)
F: icam-1 (canis lupus familiaris) (aka intercellular adhesion molecule 1)
G: intercellular adhesion molecule 1, related sequence 1 (mus musculus) (aka intercellular adhesion molecule 1, related sequence 1)
H: icam-2 (mus musculus) (aka intercellular adhesion molecule 2)
I: intercellular adhesion molecule 1 (homo sapiens) (aka intercellular adhesion molecule 1)
J: icam4 (homo sapiens) (aka intercellular adhesion molecule 4 (landsteiner-wiener blood group))
K: None of the above. | I |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'vcam-1'. Answer using one of the provided options. | <Options>: A: vcam1 (bos taurus) (aka vascular cell adhesion molecule 1)
B: platelet and endothelial cell adhesion molecule 1 (homo sapiens) (aka platelet and endothelial cell adhesion molecule 1)
C: vascular cell adhesion molecule 1 (homo sapiens) (aka vascular cell adhesion molecule 1)
D: vascular cell adhesion molecule 1 (canis lupus familiaris) (aka vascular cell adhesion molecule 1)
E: vcam1 (mus caroli) (aka vascular cell adhesion molecule 1)
F: vcam1 (oryctolagus cuniculus) (aka vascular cell adhesion molecule 1)
G: vcam1 (gallus gallus) (aka vascular cell adhesion molecule 1)
H: vcam1 (cricetulus griseus) (aka vascular cell adhesion molecule 1)
I: vcam1 (rattus norvegicus) (aka vascular cell adhesion molecule 1)
J: vascular cell adhesion molecule 1 (sus scrofa) (aka vascular cell adhesion molecule 1)
K: None of the above. | C |
<Instruct>: Given the context 'Heterodimeric S100A8/S100A9 enhanced secretion of IL-6, ICAM-1, VCAM-1 and MCP1 in AGE-albumin pretreated HUVEC in a dose dependent manner.', select the correct biomedical concept corresponding to 'mcp1'. Answer using one of the provided options. | <Options>: A: mcp-1 (caenorhabditis elegans) (aka gdp-d-glucose phosphorylase 1)
B: scya1 (homo sapiens) (aka c-c motif chemokine ligand 1)
C: mcp-2 (homo sapiens) (aka c-c motif chemokine ligand 8)
D: c-x-c motif chemokine ligand 1 (homo sapiens) (aka c-x-c motif chemokine ligand 1)
E: ncc-1 (homo sapiens) (aka c-c motif chemokine ligand 13)
F: mcp7-like (homo sapiens) (aka tryptase delta 1)
G: mcp-3 (homo sapiens) (aka c-c motif chemokine ligand 7)
H: mcp-1 (mus musculus) (c-c motif chemokine ligand 2 (mus musculus)) (aka c-c motif chemokine ligand 2)
I: chemokine (c motif) ligand 1 (mus musculus) (aka chemokine (c motif) ligand 1)
J: ccl2 (homo sapiens) (aka c-c motif chemokine ligand 2)
K: None of the above. | J |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
B: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
C: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
D: s100a18 (homo sapiens) (aka hornerin)
E: s100a1 (homo sapiens) (aka s100 calcium binding protein a1)
F: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
G: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
H: s100a8 (canis lupus familiaris) (aka s100 calcium binding protein a8)
I: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
J: p8 (homo sapiens) (s100 calcium binding protein a8 (homo sapiens)) (aka s100 calcium binding protein a8)
K: None of the above. | J |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
B: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a1l (homo sapiens) (aka sentan, cilia apical structure protein)
D: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
E: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
F: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
G: s100a11 (homo sapiens) (aka s100 calcium binding protein a11)
H: s100a7b (homo sapiens) (aka s100 calcium binding protein a7 like 2)
I: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
J: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
K: None of the above. | B |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100a1'. Answer using one of the provided options. | <Options>: A: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
B: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
C: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
D: s100a (xenopus laevis) (s100 calcium binding protein a1 l homeolog (xenopus laevis)) (aka s100 calcium binding protein a1 l homeolog)
E: s100a11 (homo sapiens) (aka s100 calcium binding protein a11)
F: s100a15a (homo sapiens) (aka s100 calcium binding protein a15a (pseudogene))
G: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
H: s100a1l (gallus gallus) (aka sentan, cilia apical structure protein)
I: s100-a1 (xenopus laevis) (s100 calcium binding protein a1 s homeolog (xenopus laevis)) (aka s100 calcium binding protein a1 s homeolog)
J: s100 calcium binding protein a1 (homo sapiens) (aka s100 calcium binding protein a1)
K: None of the above. | J |
<Instruct>: Given the context 'These effects could not be detected after stimulation with the homodimeric proteins S100A8, S100A9, S100A1 and S100B.', select the correct biomedical concept corresponding to 's100b'. Answer using one of the provided options. | <Options>: A: protein s100-b-like (xenopus laevis) (aka protein s100-b-like)
B: s100p (homo sapiens) (aka s100 calcium binding protein p)
C: s100l (homo sapiens) (aka s100 calcium binding protein a2)
D: s100b (gallus gallus) (aka s100 calcium binding protein b)
E: s100-alpha (homo sapiens) (aka s100 calcium binding protein a1)
F: s100e (homo sapiens) (aka s100 calcium binding protein a3)
G: s100g (homo sapiens) (aka s100 calcium binding protein g)
H: s100c (homo sapiens) (aka s100 calcium binding protein a11)
I: s100b (canis lupus familiaris) (aka s100 calcium binding protein b)
J: s100-b (homo sapiens) (aka s100 calcium binding protein b)
K: None of the above. | J |
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
B: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
C: s100a18 (homo sapiens) (aka hornerin)
D: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
E: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
F: s100-a8 (homo sapiens) (aka s100 calcium binding protein a8)
G: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
H: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
I: s100a (homo sapiens) (aka s100 calcium binding protein a1)
J: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
K: None of the above. | F |
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
B: s100a9 (gallus gallus) (aka s100 calcium binding protein a12)
C: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
D: s100a (homo sapiens) (aka s100 calcium binding protein a1)
E: s100a (xenopus laevis) (s100 calcium binding protein a1 s homeolog (xenopus laevis)) (aka s100 calcium binding protein a1 s homeolog)
F: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
G: s100a1l (homo sapiens) (aka sentan, cilia apical structure protein)
H: s100a11 (homo sapiens) (aka s100 calcium binding protein a11)
I: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
J: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
K: None of the above. | A |
<Instruct>: Given the context 'The effects of heterodimeric S100A8/S100A9 were reduced by inhibition of the MAP-kinase pathways ERK1/2 and p38 by PD 98059 and SB 203580, respectively.', select the correct biomedical concept corresponding to 'p38'. Answer using one of the provided options. | <Options>: A: p38b (homo sapiens) (aka mitogen-activated protein kinase 11)
B: p38 (drosophila melanogaster) (p38b map kinase (drosophila melanogaster)) (aka p38b map kinase)
C: p38gamma (homo sapiens) (aka mitogen-activated protein kinase 12)
D: p38mapk (drosophila melanogaster) (p38a map kinase (drosophila melanogaster)) (aka p38a map kinase)
E: p38alpha (homo sapiens) (aka mitogen-activated protein kinase 14)
F: p38 (homo sapiens) (mitogen-activated protein kinase 1 (homo sapiens)) (aka mitogen-activated protein kinase 1)
G: p38[mapk] (drosophila melanogaster) (aka p38c map kinase)
H: p38-alpha (mus musculus) (aka mitogen-activated protein kinase 14)
I: None of the above. | E |
<Instruct>: Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
B: s100 calcium binding protein a8 (homo sapiens) (aka s100 calcium binding protein a8)
C: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
D: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
E: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
F: s100a12 (homo sapiens) (aka s100 calcium binding protein a12)
G: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
H: s100a (homo sapiens) (aka s100 calcium binding protein a1)
I: s100 calcium binding protein a8 (canis lupus familiaris) (aka s100 calcium binding protein a8)
J: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
K: None of the above. | B |
<Instruct>: Given the context 'The heterodimeric S100A8/S100A9 might therefore play a hitherto unknown role in triggering atherosclerosis in diabetes and renal failure, pathophysiological entities associated with a high AGE burden.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
B: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a9 (gallus gallus) (aka s100 calcium binding protein a12)
D: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
E: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
F: s100a11 (homo sapiens) (aka s100 calcium binding protein a11)
G: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
H: s100a9 (canis lupus familiaris) (aka s100 calcium binding protein a9)
I: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
J: s100a (homo sapiens) (aka s100 calcium binding protein a1)
K: None of the above. | B |
<Instruct>: Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', select the correct biomedical concept corresponding to 's100a8'. Answer using one of the provided options. | <Options>: A: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
B: s100a9 (homo sapiens) (aka s100 calcium binding protein a9)
C: s100a18 (homo sapiens) (aka hornerin)
D: s100a8 (canis lupus familiaris) (aka s100 calcium binding protein a8)
E: s100a6 (homo sapiens) (aka s100 calcium binding protein a6)
F: s100a5 (homo sapiens) (aka s100 calcium binding protein a5)
G: s100al (homo sapiens) (aka sentan, cilia apical structure protein)
H: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
I: s100a10 (homo sapiens) (aka s100 calcium binding protein a10)
J: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
K: None of the above. | A |
<Instruct>: Given the context 'Thus, blocking heterodimeric S100A8/S100A9 might represent a novel therapeutic modality in treating atherosclerosis.', select the correct biomedical concept corresponding to 's100a9'. Answer using one of the provided options. | <Options>: A: s100a1 (homo sapiens) (aka s100 calcium binding protein a1)
B: s100a3 (homo sapiens) (aka s100 calcium binding protein a3)
C: s100a4 (homo sapiens) (aka s100 calcium binding protein a4)
D: s100a1l (homo sapiens) (aka sentan, cilia apical structure protein)
E: s100 calcium binding protein a9 (homo sapiens) (aka s100 calcium binding protein a9)
F: s100a2 (homo sapiens) (aka s100 calcium binding protein a2)
G: s100a (xenopus laevis) (s100 calcium binding protein a1 s homeolog (xenopus laevis)) (aka s100 calcium binding protein a1 s homeolog)
H: s100a7 (homo sapiens) (aka s100 calcium binding protein a7)
I: s100a9 (canis lupus familiaris) (aka s100 calcium binding protein a9)
J: s100a8 (homo sapiens) (aka s100 calcium binding protein a8)
K: None of the above. | E |
<Instruct>: Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', select the correct biomedical concept corresponding to 'growth hormone'. Answer using one of the provided options. | <Options>: A: gh2 (homo sapiens) (aka growth hormone 2)
B: ghl (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
C: growth hormone 1 (rattus norvegicus) (aka growth hormone 1)
D: growth hormone (gallus gallus) (aka growth hormone)
E: ghn (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
F: gh (homo sapiens) (growth hormone 1 (homo sapiens)) (aka growth hormone 1)
G: gh (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
H: ghs (homo sapiens) (aka goldenhar syndrome)
I: growth hormone (mus musculus) (aka growth hormone)
J: None of the above. | F |
<Instruct>: Given the context 'Human growth hormone (GH1) gene polymorphism map in a normal-statured adult population.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: gh1-a (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
B: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
C: gh (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
D: growth hormone 1 (homo sapiens) (aka growth hormone 1)
E: gh2 (homo sapiens) (aka growth hormone 2)
F: ghs (homo sapiens) (aka goldenhar syndrome)
G: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
H: gha1 (homo sapiens) (aka prolactin)
I: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
J: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
K: None of the above. | D |
<Instruct>: Given the context 'OBJECTIVE: GH1 gene presents a complex map of single nucleotide polymorphisms (SNPs) in the entire promoter, coding and noncoding regions.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
B: gh1 (homo sapiens) (aka growth hormone 1)
C: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
D: ghl (homo sapiens) (aka growth hormone 2)
E: ghs (homo sapiens) (aka goldenhar syndrome)
F: gh-n (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
G: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
H: gh1-a (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
I: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
J: gha1 (homo sapiens) (aka prolactin)
K: None of the above. | B |
<Instruct>: Given the context 'The aim of the study was to establish the complete map of GH1 gene SNPs in our control normal population and to analyse its association with adult height.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: ghs (homo sapiens) (aka goldenhar syndrome)
B: gh1-a (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
C: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
D: gh-n (homo sapiens) (aka growth hormone 1)
E: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
F: gh1-b (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
G: gha1 (homo sapiens) (aka prolactin)
H: gh-v (homo sapiens) (aka growth hormone 2)
I: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
J: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
K: None of the above. | D |
<Instruct>: Given the context 'DESIGN, SUBJECTS AND MEASUREMENTS: A systematic GH1 gene analysis was designed in a control population of 307 adults of both sexes with height normally distributed within normal range for the same population: -2 standard deviation scores (SDS) to +2 SDS.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
B: gh1-a (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
C: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
D: gha1 (homo sapiens) (aka prolactin)
E: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
F: growth hormone 1 (homo sapiens) (aka growth hormone 1)
G: ghs (homo sapiens) (aka goldenhar syndrome)
H: gh (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
I: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
J: ghl (homo sapiens) (aka growth hormone 2)
K: None of the above. | F |
<Instruct>: Given the context 'This study established the GH1 gene sequence variation map in a normal adult height control population confirming the high density of SNPs in a relatively small gene.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: ghs (homo sapiens) (aka goldenhar syndrome)
B: gh1-b (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
C: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
D: gha1 (homo sapiens) (aka prolactin)
E: gh (homo sapiens) (growth hormone 1 (homo sapiens)) (aka growth hormone 1)
F: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
G: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
H: gh (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
I: ghl (homo sapiens) (aka growth hormone 2)
J: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
K: None of the above. | E |
<Instruct>: Given the context 'Systematic GH1 gene analysis in patients with growth delay and suspected GH deficiency/insufficiency will clarify whether different SNP frequencies and/or the presence of different sequence changes may be associated with phenotypes in them.', select the correct biomedical concept corresponding to 'gh1'. Answer using one of the provided options. | <Options>: A: gh1 (drosophila melanogaster) (aka mitochondrial ribosomal protein s11)
B: ghf-1 (homo sapiens) (aka pou class 1 homeobox 1)
C: gh1-a (xenopus laevis) (growth hormone 2 s homeolog (xenopus laevis)) (aka growth hormone 2 s homeolog)
D: gh1 (homo sapiens) (aka growth hormone 1)
E: gh1-b (xenopus laevis) (growth hormone 1 l homeolog (xenopus laevis)) (aka growth hormone 1 l homeolog)
F: ghs (homo sapiens) (aka goldenhar syndrome)
G: ghb1 (homo sapiens) (aka chorionic somatomammotropin hormone 2)
H: ghl (homo sapiens) (aka growth hormone 2)
I: gha1 (homo sapiens) (aka prolactin)
J: ghn (xenopus laevis) (growth hormone 1 s homeolog (xenopus laevis)) (aka growth hormone 1 s homeolog)
K: None of the above. | D |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'ccr2'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor-like 2 (mus musculus) (aka c-c motif chemokine receptor-like 2)
B: ccr2b (homo sapiens) (aka c-c motif chemokine receptor 2)
C: c-c motif chemokine receptor 2 (mus musculus) (aka c-c motif chemokine receptor 2)
D: mcp-1-r (xenopus laevis) (chemokine (c-c motif) receptor 2 s homeolog (xenopus laevis)) (aka chemokine (c-c motif) receptor 2 s homeolog)
E: ccr10 (homo sapiens) (atypical chemokine receptor 2 (homo sapiens)) (aka atypical chemokine receptor 2)
F: c-c motif chemokine receptor like 2 (homo sapiens) (aka c-c motif chemokine receptor like 2)
G: ccr2b (xenopus laevis) (chemokine (c-c motif) receptor 2 l homeolog (xenopus laevis)) (aka chemokine (c-c motif) receptor 2 l homeolog)
H: None of the above. | B |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'ccr5'. Answer using one of the provided options. | <Options>: A: c-c chemokine receptor type 5 (mus caroli) (aka c-c chemokine receptor type 5)
B: ckr5 (homo sapiens) (aka c-c motif chemokine receptor 5)
C: ccr5as (homo sapiens) (aka ccr5 antisense rna)
D: cc-ckr-7 (homo sapiens) (aka c-c motif chemokine receptor 7)
E: ccr5 (sus scrofa) (aka c-c motif chemokine receptor 5)
F: atypical chemokine receptor 5 (homo sapiens) (aka atypical chemokine receptor 5)
G: c-x-c motif chemokine receptor 5 (mus caroli) (aka c-x-c motif chemokine receptor 5)
H: c-c motif chemokine receptor 5 (mus musculus) (aka c-c motif chemokine receptor 5)
I: c-x-c motif chemokine receptor 5 (homo sapiens) (aka c-x-c motif chemokine receptor 5)
J: atypical chemokine receptor 5 (mus caroli) (aka atypical chemokine receptor 5)
K: None of the above. | B |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'cox1'. Answer using one of the provided options. | <Options>: A: cox1 (xenopus laevis) (cytochrome c oxidase subunit i (xenopus laevis)) (aka cytochrome c oxidase subunit i)
B: cox1 (homo sapiens) (mitochondrially encoded cytochrome c oxidase i (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase i)
C: cox10 (homo sapiens) (aka cytochrome c oxidase assembly factor heme a:farnesyltransferase cox10)
D: cox1 (homo sapiens) (prostaglandin-endoperoxide synthase 1 (homo sapiens)) (aka prostaglandin-endoperoxide synthase 1)
E: cox1 (necator americanus) (aka cytochrome c oxidase subunit i)
F: cox3 (homo sapiens) (mitochondrially encoded cytochrome c oxidase iii (homo sapiens)) (aka mitochondrially encoded cytochrome c oxidase iii)
G: cox1 (caenorhabditis elegans) (aka cytochrome c oxidase subunit i)
H: cox17 (homo sapiens) (aka cytochrome c oxidase copper chaperone cox17)
I: coxii (homo sapiens) (aka mt-co2 pseudogene 12)
J: cox iv-1 (homo sapiens) (aka cytochrome c oxidase subunit 4i1)
K: None of the above. | D |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'cox2'. Answer using one of the provided options. | <Options>: A: cox2 (oryctolagus cuniculus) (aka cytochrome c oxidase subunit ii)
B: cox25 (homo sapiens) (aka cytochrome c oxidase assembly factor 3)
C: cox23 (homo sapiens) (aka coiled-coil-helix-coiled-coil-helix domain containing 7)
D: cox2 (drosophila melanogaster) (aka mitochondrial cytochrome c oxidase subunit ii)
E: cox2 (ovis aries) (aka cytochrome c oxidase subunit ii)
F: cox2 (cricetulus griseus) (aka cytochrome c oxidase subunit ii)
G: ptgs2 (homo sapiens) (aka prostaglandin-endoperoxide synthase 2)
H: cox20, cytochrome c oxidase assembly factor (gallus gallus) (aka cox20, cytochrome c oxidase assembly factor)
I: cox2 (xenopus laevis) (prostaglandin-endoperoxide synthase 2 l homeolog (xenopus laevis)) (aka prostaglandin-endoperoxide synthase 2 l homeolog)
J: cox2 (schizosaccharomyces pombe) (aka cytochrome oxidase subunit 2)
K: None of the above. | G |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'crp'. Answer using one of the provided options. | <Options>: A: crp-1 (caenorhabditis elegans) (aka cdc-42 related protein)
B: crp1 (mus musculus) (cysteine-rich protein 1 (mus musculus)) (aka cysteine-rich protein 1)
C: crp3 (homo sapiens) (cysteine and glycine rich protein 3 (homo sapiens)) (aka cysteine and glycine rich protein 3)
D: crp2 (homo sapiens) (cysteine rich protein 2 (homo sapiens)) (aka cysteine rich protein 2)
E: crp1 (homo sapiens) (cysteine and glycine rich protein 1 (homo sapiens)) (aka cysteine and glycine rich protein 1)
F: c-reactive protein (homo sapiens) (aka c-reactive protein)
G: crp1 (drosophila melanogaster) (aka nucleoplasmin)
H: crp-1 (homo sapiens) (aka cysteine rich protein 1)
I: crp1 (xenopus laevis) (cysteine-rich protein 1 (intestinal) s homeolog (xenopus laevis)) (aka cysteine-rich protein 1 (intestinal) s homeolog)
J: crp-3 (homo sapiens) (aka cysteine rich protein 3)
K: None of the above. | F |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'csf1'. Answer using one of the provided options. | <Options>: A: csf2 (homo sapiens) (aka colony stimulating factor 2)
B: colony stimulating factor 1 (cricetulus griseus) (aka colony stimulating factor 1)
C: csf-3 (xenopus laevis) (colony stimulating factor 3 s homeolog (xenopus laevis)) (aka colony stimulating factor 3 s homeolog)
D: csf1 (gallus gallus) (aka colony stimulating factor 1)
E: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
F: csf1 (mus musculus) (aka colony stimulating factor 1 (macrophage))
G: colony stimulating factor 1 (rattus norvegicus) (aka colony stimulating factor 1)
H: csf-1 (homo sapiens) (aka colony stimulating factor 1)
I: mgf (homo sapiens) (kit ligand (homo sapiens)) (aka kit ligand)
J: colony stimulating factor 1 (mus caroli) (aka colony stimulating factor 1)
K: None of the above. | H |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'csf2'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 2 (canis lupus familiaris) (aka colony stimulating factor 2)
B: csf (homo sapiens) (colony stimulating factor 2 (homo sapiens)) (aka colony stimulating factor 2)
C: colony stimulating factor 2 (sus scrofa) (aka colony stimulating factor 2)
D: interleukin 2 (homo sapiens) (aka interleukin 2)
E: csf3 (homo sapiens) (aka colony stimulating factor 3)
F: colony stimulating factor 2 (ovis aries) (aka colony stimulating factor 2)
G: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
H: csf-3 (xenopus laevis) (colony stimulating factor 3 s homeolog (xenopus laevis)) (aka colony stimulating factor 3 s homeolog)
I: colony stimulating factor 2 (mus caroli) (aka colony stimulating factor 2)
J: colony stimulating factor 2 (rattus norvegicus) (aka colony stimulating factor 2)
K: None of the above. | B |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'ifng'. Answer using one of the provided options. | <Options>: A: ifn (xenopus laevis) (uncharacterized loc108702184 (xenopus laevis)) (aka uncharacterized loc108702184)
B: ifn1@ (homo sapiens) (aka interferon, type 1, cluster)
C: ifngm2 (homo sapiens) (aka interferon production regulator)
D: ifng (cricetulus griseus) (aka interferon gamma)
E: ifna5 (homo sapiens) (aka interferon alpha 5)
F: ifng (canis lupus familiaris) (aka interferon gamma)
G: interferon gamma (homo sapiens) (aka interferon gamma)
H: ifng (gallus gallus) (interferon gamma (gallus gallus)) (aka interferon gamma)
I: ifng (xenopus tropicalis) (aka interferon gamma)
J: ifn (xenopus laevis) (type i intron-contaning interferon 4 s homeolog (xenopus laevis)) (aka type i intron-contaning interferon 4 s homeolog)
K: None of the above. | G |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il1a'. Answer using one of the provided options. | <Options>: A: il1a (canis lupus familiaris) (aka interleukin 1 alpha)
B: il1f11 (homo sapiens) (aka interleukin 33)
C: il-1h (homo sapiens) (aka interleukin 37)
D: il1-eta (homo sapiens) (aka interleukin 36 beta)
E: il1h1 (homo sapiens) (aka interleukin 36 gamma)
F: il1f2 (homo sapiens) (aka interleukin 1 beta)
G: il1l1 (homo sapiens) (aka interleukin 36 receptor antagonist)
H: il1 (homo sapiens) (aka interleukin 1 alpha)
I: il1a (mus musculus) (aka interleukin 1 alpha)
J: None of the above. | H |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il1b'. Answer using one of the provided options. | <Options>: A: il1b (canis lupus familiaris) (aka interleukin 1 beta)
B: il1f11 (homo sapiens) (aka interleukin 33)
C: il1h2 (homo sapiens) (aka interleukin 36 beta)
D: il1f3 (homo sapiens) (aka interleukin 1 receptor antagonist)
E: il1f1 (homo sapiens) (aka interleukin 1 alpha)
F: il1hy2 (homo sapiens) (aka interleukin 1 family member 10)
G: il1f4 (homo sapiens) (aka interleukin 18)
H: il1beta (homo sapiens) (aka interleukin 1 beta)
I: il1l1 (homo sapiens) (aka interleukin 36 receptor antagonist)
J: il11 (homo sapiens) (aka interleukin 11)
K: None of the above. | H |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il2'. Answer using one of the provided options. | <Options>: A: interleukin 2 (homo sapiens) (aka interleukin 2)
B: il26 (homo sapiens) (aka interleukin 26)
C: il25 (homo sapiens) (interleukin 25 (homo sapiens)) (aka interleukin 25)
D: interleukin 2 (canis lupus familiaris) (aka interleukin 2)
E: il25 (homo sapiens) (myeloid derived growth factor (homo sapiens)) (aka myeloid derived growth factor)
F: il-3 (homo sapiens) (aka interleukin 3)
G: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
H: interleukin 2 (cricetulus griseus) (aka interleukin 2)
I: il21 (homo sapiens) (aka interleukin 21)
J: il2 (mus musculus) (aka interleukin 2)
K: None of the above. | A |
<Instruct>: Given the context 'The genes in which SNPs were analyzed include CCR2, CCR5, COX1, COX2, CRP, CSF1, CSF2, IFNG, IL1A, IL1B, IL2, IL4, IL6, IL8, IL10, IL13, IL18, LTA, MPO, NOS2A, NOS3, PPARD, PPARG, PPARGC1 and TNF.', select the correct biomedical concept corresponding to 'il4'. Answer using one of the provided options. | <Options>: A: interleukin-4 (gallus gallus) (aka interleukin 4)
B: il3 (homo sapiens) (aka interleukin 3)
C: interleukin 4 (ovis aries) (aka interleukin 4)
D: il-4 (homo sapiens) (aka interleukin 4)
E: il4 (bos taurus) (aka interleukin 4)
F: interleukin 4 (cricetulus griseus) (aka interleukin 4)
G: il-4 (canis lupus familiaris) (aka interleukin 4)
H: il-5 (homo sapiens) (aka interleukin 5)
I: interleukin 4 (mus musculus) (aka interleukin 4)
J: None of the above. | D |
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