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10.1371_journal.pcbi.1011775.pdf
Data Availability Statement: The software “ImportRisk-v1.0.0” to compute the import risk is available under the Zenodo repository https://doi.org/10.5281/zenodo.7852476.
The software 'ImportRisk-v1.0.0' to compute the import risk is available under the Zenodo repository https://doi. org/10.5281/zenodo.7852476 .
10.1167_jov.23.6.7.pdf
The configurations and codes for this experiment are available in: Github github.com/Znasif/ColorCalibration, Google Colab colab.research.google.com/drive/1eHDXJPRn3HaeAqcdGbOKHVJSiNBXBCMv.
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10.1371_journal.pmed.1003998.pdf
Data Availability Statement Data will be available to successful applications for clearly specified research projects following the MRC CTU at UCL standard data sharing processes: https://www.mrcctu.ucl.ac.uk/our-research/other-research-policy/data-sharing/ Discussion with the trial team is encouraged to determine whether the relevant data to support the application are available. Email to: mrcctu.datareleaserequest@ucl.ac.uk.
Data will be available to successful applications for clearly specified research projects following /our-research/other-research- policy/data-sharing/ Discussion with the trial team is encouraged to determine whether the relevant data to support the application are available. .
10.7554_elife.86784.pdf
Data availabilityCryo-EM maps and atomic coordinates for the GC-C-Hsp90-Cdc37 complex have been deposited in the EMDB (EMD-29523) and PDB (8FX4). Material availability: The plasmids used in this study are uploaded in (Supplementary file 1).
Data availability Cryo-EM maps and atomic coordinates for the GC-C-Hsp90-Cdc37 complex have been deposited in the EMDB (EMD-29523) and PDB (8FX4). Material availability: The plasmids used in this study are uploaded in (Supplementary file 1). The following datasets were generated:
10.1038_s41467-022-32646-w.pdf
Data availability The data that support the findings in this study are available from the corresponding authors upon reasonable request. Source data are provided with this paper. Code availability All code to reproduce the main simulation results can be found on GitHub (https://github.com/babaf/motor-adaptation-local-vs-input.git).
Data availability The data that support the findings in this study are available from the corresponding authors upon reasonable request. Source data are provided with this paper. Code availability All code to reproduce the main simulation results can be found on GitHub ( https://github.com/babaf/motor-adaptation-local-vs-input.git ).
10.1371_journal.pone.0219089.pdf
Data Availability Statement All relevant data are within the paper and its Supporting Information files.
All relevant data are within the paper and its Supporting Information files.
10.1242/dmm.041962
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10.1093_pnasnexus_pgad113.pdf
Data availability The processed experimental files for all single-cell data sets used in this study are available on Zenodo at https://doi.org/10.5281/zenodo.7474099; Table 1 lists the Gene Expression Omnibus (GEO) accession numbers for each data set. The saved model weights for DELAY are available on Zenodo at https://doi.org/10.5281/zenodo.7474115. All experimental logs from this study are available at https://tensorboard.dev/experiment/RBVBetLMRDiEvO7sBl452A. We have provided an open-source implementation of DELAY in PyTorch with listed requirements and documentation at https://github.com/calebclayreagor/DELAY.
Data availability The processed experimental files for all single-cell data sets used in this study are available on Zenodo at https://doi.org/10.5281/ zenodo.7474099 ; Table 1 lists the Gene Expression Omnibus (GEO) accession numbers for each data set. The saved model weights for DELAY are available on Zenodo at https://doi.org/10. 5281/zenodo.7474115 . All experimental logs from this study are available at https://tensorboard.dev/experiment/RBVBetLM RDiEvO7sBl452A . We have provided an open-source implementation of DELAY in PyTorch with listed requirements and documentation at https://github.com/calebclayreagor/DELAY .
10.1371_journal.pone.0294847.pdf
Data Availability Statement: All relevant data are within the paper and its Supporting information files.
Data Availability Statement: All relevant data are within the paper and its Supporting information files. Funding: The ATL1102 in DMD clinical trial was funded in its entirety by the sponsor Antisense Therapeutics Ltd. Authors Ms Desem and Dr Tachas are employees of the sponsor and so received payment for services from the sponsor as employees. Ms. Desem and Dr Tachas hold an equity interest in the sponsor. Dr Tachas and Ms Desem along with other sponsor employees and sub-contracted specialists were involved in the study design and data analysis. Authors Dr Woodcock and Dr Ryan were at the time of the trial employees of the Royal Children's Hospital and Murdoch Children's Research Institute and are not affiliated with the sponsor in any way and have not received any direct personal payment or honoraria from the sponsors, nor do they or their family members hold a financial interest or stock in the sponsor company. Dr Woodcock is still an employee of the above institutions, but Dr Ryan has since left the employment to take up public office. Dr Woodcock and Dr Ryan were involved in the trial design as unpaid consultants. As this was a clinical trial, publication was always planned from trial inception. No employees of the sponsor were involved in the data collection, although Ms Desem did liaise closely with the MCRI/RCH site staff and Clinical Trial Organisation throughout the trial. Author Dr Button was paid for services as the study statistician. None of the other authors received any payment from the sponsor to conduct this study. All other authors had input into writing or revising this manuscript. ATL1102 is a second-generation immunomodulatory 2'MOE gapmer antisense oligonucleotide which specifically targets human CD49d RNA. After binding to the RNA of CD49d, intracellular RNase H attaches resulting in downregulation of CD49d RNA. ATL1102 has previously been trialled to treat Relapsing Remitting Multiple Sclerosis (RRMS), noting that CD49d high expressing T cells are the effector and central memory T cells in RRMS. In this phase 2 RRMS clinical trial, ATL1102 dosed 200mg three times weekly in the first week and twice weekly to 8 weeks substantially reduced inflammatory brain lesions by 88.5% and circulating lymphocytes and T lymphocytes by 25% [10] . Reported here, collaborators from the same institution ran two separate but complementary studies. The initial trial, a phase 2 clinical trial examining for the first time the safety and efficacy of a low dose ATL1102 treatment for 24 weeks in non-ambulant patients with DMD on concomitant corticosteroid treatment. The second, a pre-clinical study in the mdx mouse model for DMD, conducted using a mouse specific second generation CD49d ASO (ISIS 348574) to show that monotherapy treatment can reduce CD49d mRNA expression in muscle and decrease contraction induced muscle damage.
10.1107_s2052252522010612.pdf
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10.1371_journal.pone.0243922.pdf
Data Availability Statement All relevant data are within the paper and its Supporting Information files.
All relevant data are within the paper and its Supporting Information files.
10.1103_physrevresearch.5.013168.pdf
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10.1017_jfm.2023.90.pdf
Data availability statement. The codes used in this study are openly available in GitHub at https://github. com/Maplenormandy/qg-edgeofchaos.
Data availability statement. The codes used in this study are openly available in GitHub at https://github. com/Maplenormandy/qg-edgeofchaos .
10.1371_journal.ppat.1011346.pdf
Data Availability Statement All relevant data are within the manuscript and its Supporting Information files.
All relevant data are within the manuscript and its Supporting Information files.
10.1371_journal.pone.0269555.pdf
Data Availability Statement All relevant data are within the paper and its Supporting Information files.
All relevant data are within the paper and its Supporting Information files.
10.1038/s41467-022-29297-2
Data availability The microbial growth data generated in this study are provided in the Supplementary Table S2. Code availability The model code is deposited on GitHub (https://github.com/LevineLab/POMmodel) and citable using https://doi.org/10.5281/zenodo.6015020.
Data availability The microbial growth data generated in this study are provided in the Supplementary Table S2 . Code availability The model code is deposited on GitHub ( https://github.com/LevineLab/POMmodel ) and citable using https://doi.org/10.5281/zenodo.6015020 .
10.1073_pnas.1913292117.pdf
Data Availability Statement. All data discussed in the paper are available to readers through Harvard Dataverse, https://doi.org/10.7910/DVN/RFGT4S.
Data Availability Statement. All data discussed in the paper are available to readers through Harvard Dataverse, https://doi.org/10.7910/DVN/RFGT4S .
10.1371_journal.pntd.0010231.pdf
Data Availability Statement De-identified data is available online via the COR-NTD Research Dataverse: https://dataverse.unc.edu/dataset.xhtml?persistentId=doi:10.15139/S3/WOYRUW.
De-identified data is available online via the COR-NTD Research Dataverse: https://dataverse.unc.edu/dataset. xhtml?persistentId=doi:10.15139/S3/WOYRUW .
10.1371_journal.pmed.1002934.pdf
Data Availability Statement A minimal dataset and STATA DO file are included as Supporting information files to enable readers to replicate our analysis.
A minimal dataset and STATA DO file are included as Supporting information files to enable readers to replicate our analysis.
10.1088_1361-6552_ad001a.pdf
Data availability statementThe data cannot be made publicly available upon publication due to legal restrictions preventing unrestricted public distribution. The data that support the findings of this study are available upon reasonable request from the authors.
Data availability statement The data cannot be made publicly available upon publication due to legal restrictions preventing unrestricted public distribution. The data that support the findings of this study are available upon reasonable request from the authors.
10.1371_journal.pone.0296688.pdf
Data Availability Statement: All data files are available from the OpenBU database (https://hdl.handle.net/2144/45321).
All data files are available from the OpenBU database ( https://hdl. handle.net/2144/45321 ).
10.1103_physrevd.107.023530.pdf
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10.1371_journal.pcbi.1007117.pdf
Data Availability Statement All relevant data are within the manuscript and its Supporting Information files.
All relevant data are within the manuscript and its Supporting Information files.
10.1088_1402-4896_ad16b7.pdf
Data availability statementThe data that support the findings of this study are available upon reasonable request from the authors.
Data availability statement The data that support the findings of this study are available upon reasonable request from the authors.
10.1016_j.isci.2021.102204.pdf
Data and code availability The data that support the findings of this study and sequences were submitted to the NCBI sequence read archive (SRA) under BioProject ID: PRJNA633714. Code for analysis is available on github repository: https://github.com/galud27.
Data and code availability The data that support the findings of this study and sequences were submitted to the NCBI sequence read archive (SRA) under BioProject ID: PRJNA633714. Code for analysis is available on github repository: https://github.com/galud27 .
10.1371_journal.pone.0253387.pdf
Data Availability Statement Raw genome sequencing data for 23 strains are available from the NCBI with BioProject PRJNA683613.
Raw genome sequencing data for 23 strains are available from the NCBI with BioProject PRJNA683613.