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10.1126_science.adf0566
RES EARCH R E S E A R C H A R T I C L E ◥ SLEEP Brain activity of diving seals reveals short sleep cycles at depth Jessica M. Kendall-Bar1,2*, Terrie M. Williams2, Ritika Mukherji3, Daniel A. Lozano2, Julie K. Pitman4, Rachel R. Holser5, Theresa Keates6, Roxanne S. Beltran2, Patrick W. Robinson2, Daniel E. Crocker...
10.1126_science.adf2698
RES EARCH SEMICONDUCTORS Room-temperature wavelike exciton transport in a van der Waals superatomic semiconductor Jakhangirkhodja A. Tulyagankhodjaev, Petra Shih†, Jessica Yu†, Jake C. Russell, Daniel G. Chica, Michelle E. Reynoso, Haowen Su, Athena C. Stenor, Xavier Roy, Timothy C. Berkelbach, Milan Delor* The tra...
10.1126_science.adf2040
RES EARCH 2D MATERIALS A quantum ruler for orbital magnetism in moiré quantum matter M. R. Slot1,2†, Y. Maximenko1,3†, P. M. Haney1, S. Kim1,4, D. T. Walkup1, E. Strelcov1,3, Son T. Le1, E. M. Shih1,3, D. Yildiz1,4, S. R. Blankenship1, K. Watanabe5, T. Taniguchi6, Y. Barlas7, N. B. Zhitenev1, F. Ghahari8*, J. A. Str...
10.1126_science.ade4441
RES EARCH 3D PRINTING A silicone-based support material eliminates interfacial instabilities in 3D silicone printing Senthilkumar Duraivel1, Dimitri Laurent2, Didier A. Rajon2, Georg M. Scheutz3, Abhishek M. Shetty4, Brent S. Sumerlin3, Scott A. Banks5, Frank J. Bova2, Thomas E. Angelini1,5,6* Among the diverse are...
10.1126_science.adf3971
RES EARCH R E S E A R C H A R T I C L E S U M M A R Y ◥ CELL BIOLOGY Protein import into peroxisomes occurs through a nuclear pore–like phase Yuan Gao†, Michael L. Skowyra†, Peiqiang Feng, Tom A. Rapoport* INTRODUCTION: Peroxisomes are organelles that are enclosed by a single membrane and exist in nearly all euka...
10.1126_science.adf4272
RES EARCH QUANTUM INFORMATION On-demand entanglement of molecules in a reconfigurable optical tweezer array Connor M. Holland1†, Yukai Lu1,2†, Lawrence W. Cheuk1* Entanglement is crucial to many quantum applications, including quantum information processing, quantum simulation, and quantum-enhanced sensing. Because...
10.1126_science.adf4915
RES EARCH POLLUTION Mortality risk from United States coal electricity generation Lucas Henneman1,2*, Christine Choirat3, Irene Dedoussi4, Francesca Dominici2, Jessica Roberts5, Corwin Zigler2,6 Policy-makers seeking to limit the impact of coal electricity-generating units (EGUs, also known as power plants) on air ...
10.1126_science.adf4197
RES EARCH STRUCTURAL BIOLOGY Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility Hao Wu1†, Elise N. Muñoz1,2†, Laura J. Hsieh1, Un Seng Chio1, Muryam A. Gourdet1,2*, Geeta J. Narlikar1*, Yifan Cheng1,3* Unlike other chromatin remodelers, INO80 preferentially mobilizes hexasomes, which can ...
10.1126_science.adf5273
RES EARCH MECHANOCHEMISTRY Acceleration of Diels-Alder reactions by mechanical distortion Yerzhan S. Zholdassov1,2,3, Li Yuan4, Sergio Romero Garcia5, Ryan W. Kwok2,3, Alejandro Boscoboinik4, Daniel J. Valles1,2,3, Mateusz Marianski2,3, Ashlie Martini5, Robert W. Carpick4, Adam B. Braunschweig1,2,3* Challenges in q...
10.1126_science.adf4930
RES EARCH GEOPHYSICS Ultralow frictional healing explains recurring slow slip events Srisharan Shreedharan1,2*, Demian Saffer1,3*, Laura M. Wallace1,4, Charles Williams4 Plate motion on shallow subduction megathrusts is accommodated by a spectrum of tectonic slip modes. However, the frictional properties and condit...
10.1126_science.adf5341
Climate-driven changes in soil conditions alter hibernation We used long-term climate records of air and soil temperature from two field sites, Toolik (68°38′ N, 149°38′ W; elevation 719 m) and Atigun (68°27′ N, 149°21′ W; elevation 812 m), in the Alaskan Arctic to document recent envi- ronmental change. The dataset du...
10.1126_science.adi1847
RES EARCH POPULATION DYNAMICS Boom-bust cycles in gray whales associated with dynamic and changing Arctic conditions Joshua D. Stewart1*, Trevor W. Joyce2,3, John W. Durban3,4, John Calambokidis5, Deborah Fauquier6, Holly Fearnbach4, Jacqueline M. Grebmeier7, Morgan Lynn3, Manfredi Manizza8, Wayne L. Perryman3, M. T...
10.1126_science.ade3332
RES EARCH R E S E A R C H A R T I C L E ◥ RESPIRATORY COMPLEXES Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides Hannah R. Bridges1*, James N. Blaza1,2, Zhan Yin1, Injae Chung1, Michael N. Pollak3, Judy Hirst1* The molecular mode of action of biguanides, including the drug me...
10.1126_science.adf5848
RES EARCH R E S E A R C H A R T I C L E S U M M A R Y ◥ RENEWABLE ENERGY Declining cost of renewables and climate change curb the need for African hydropower expansion Angelo Carlino, Matthias Wildemeersch, Celray James Chawanda, Matteo Giuliani, Sebastian Sterl, Wim Thiery, Ann van Griensven, Andrea Castelletti* ...
10.1126_science.adf3406
RES EARCH NEUROSCIENCE GluD1 binds GABA and controls inhibitory plasticity Laura Piot1, Christina Heroven2†‡, Simon Bossi1†, Joseph Zamith1, Tomas Malinauskas3, Chris Johnson2, Doris Wennagel1, David Stroebel1, Cécile Charrier1, A. Radu Aricescu2*, Laetitia Mony1*, Pierre Paoletti1* Fast synaptic neurotransmission ...
10.1126_science.adf8042
transfer interactions during C–H activation by metal complexes. Using time-resolved x-ray absorption spectroscopy (XAS) at the metal L-edge (11, 25–30), we probe the short-lived reaction intermediates from the vantage point of the reactive metal site to interrogate the decisive charge-transfer interactions that deter- ...
10.1126_science.adf7553
a coherent superposition of two or more states with well-separated phase-space distributions. Experimental setup Our device, which we call a ℏBAR, as in pre- vious works (19), consists of a high-overtone bulk acoustic-wave resonator (HBAR) coupled to a superconducting transmon qubit. The transmon qubit allows us to cr...
10.1126_science.adf9728
RES EARCH MESOSCOPIC PHYSICS Universal chiral Luttinger liquid behavior in a graphene fractional quantum Hall point contact Liam A. Cohen1†, Noah L. Samuelson1†, Taige Wang2,3, Takashi Taniguchi4, Kenji Watanabe5, Michael P. Zaletel2,3, Andrea F. Young1* One-dimensional conductors are described by Luttinger liquid ...
10.1126_science.adf5568
RES EARCH CHROMATIN BIOPHYSICS Stochastic motion and transcriptional dynamics of pairs of distal DNA loci on a compacted chromosome David B. Brückner1†, Hongtao Chen2,3†, Lev Barinov3,4, Benjamin Zoller5,6, Thomas Gregor3,5,6* Chromosomes in the eukaryotic nucleus are highly compacted. However, for many functional ...
10.1126_science.adg0144
RES EARCH SENSATION PIEZO2 and perineal mechanosensation are essential for sexual function Ruby M. Lam1,2, Lars J. von Buchholtz3, Melanie Falgairolle1, Jennifer Osborne1, Eleni Frangos1, M. Rocio Servin-Vences4, Maximilian Nagel1, Minh Q. Nguyen3, Monessha Jayabalan1, Dimah Saade5, Ardem Patapoutian4, Carsten G. Bö...
10.1126_science.adf5121
RES EARCH R E S E A R C H A R T I C L E S U M M A R Y ◥ MICROBIAL ECOLOGY Metabolic interaction models recapitulate leaf microbiota ecology Martin Schäfer†, Alan R. Pacheco†, Rahel Künzler, Miriam Bortfeld-Miller, Christopher M. Field, Evangelia Vayena, Vassily Hatzimanikatis, Julia A. Vorholt* INTRODUCTION: Micr...
10.1126_science.adg0727
RES EARCH MICROBIOTA Emergent coexistence in multispecies microbial communities Chang-Yu Chang1,2,3*, Djordje Bajić1,2,4*, Jean C. C. Vila1,2, Sylvie Estrela1,2†, Alvaro Sanchez1,2,5* Understanding the mechanisms that maintain microbial biodiversity is a critical aspiration in ecology. Past work on microbial coexis...
10.1126_science.adg0844
RES EARCH ANTHROPOLOGY Cooperation across social borders in bonobos Liran Samuni1,2,3* and Martin Surbeck2,4* Cooperation beyond familial and group boundaries is core to the functioning of human societies, yet its evolution remains unclear. To address this, we examined grooming, coalition, and food-sharing patterns...
10.1126_science.adg3812
150-mm-thick lithium niobate optical reso- nator placed inside a superconducting alu- minum microwave cavity at a temperature of 7 mK, described in detail in (24). The micro- wave mode âe is electro-optically coupled to the colocalized optical whispering gallery modes at wo/2p ≈ 193.46 THz through the Pockels effect (F...
10.1126_science.ade4884
RES EARCH CONSERVATION Widespread diversity deficits of coral reef sharks and rays Colin A. Simpfendorfer1,2*, Michael R. Heithaus3, Michelle R. Heupel2,4, M. Aaron MacNeil5, Mark Meekan6, Euan Harvey7, C. Samantha Sherman1,8, Leanne M. Currey-Randall4, Jordan S. Goetze9,10, Jeremy J. Kiszka3, Matthew J. Rees6,11, C...
10.1126_science.adg4421
RES EARCH CHEMICAL PHYSICS Femtosecond symmetry breaking and coherent relaxation of methane cations via x-ray spectroscopy Enrico Ridente1,2†, Diptarka Hait1,2†‡, Eric A. Haugen1,2, Andrew D. Ross1,2§, Daniel M. Neumark1,2, Martin Head-Gordon1,2, Stephen R. Leone1,2,3* Understanding the relaxation pathways of photo...
10.1126_science.adf7122
RES EARCH BIOGEOGRAPHY Paleoenvironments shaped the exchange of terrestrial vertebrates across Wallace’s Line A. Skeels1,2,3*, L. M. Boschman4, I. R. McFadden1,2,5, E. M. Joyce6, O. Hagen7, O. Jiménez Robles3,8, W. Bach1,2, V. Boussange1,2, T. Keggin1,2, W. Jetz9,10, L. Pellissier1,2 Faunal turnover in Indo-Austral...
10.1126_science.adg4084
RES EARCH R E S E A R C H A R T I C L E ◥ PHYSICS An improved bound on the electron’s electric dipole moment Tanya S. Roussy1,2†, Luke Caldwell1,2†, Trevor Wright1,2, William B. Cairncross1,2‡, Yuval Shagam1,2§, Kia Boon Ng1,2, Noah Schlossberger1,2, Sun Yool Park1,2, Anzhou Wang1,2, Jun Ye1,2, Eric A. Cornell1,2*...
10.1126_science.adg7693
RES EARCH R E S E A R C H A R T I C L E ◥ FRACTURE MECHANICS Tensile cracks can shatter classical speed limits Meng Wang, Songlin Shi, Jay Fineberg* Brittle materials fail by means of rapid cracks. Classical fracture mechanics describes the motion of tensile cracks that dissipate released elastic energy within a ...
10.1126_science.adg8155
RES EARCH R E S E A R C H A R T I C L E ◥ PHYSICS Quantum control of trapped polyatomic molecules for eEDM searches Loïc Anderegg1,2*, Nathaniel B. Vilas1,2, Christian Hallas1,2, Paige Robichaud1,2, Arian Jadbabaie3, John M. Doyle1,2, Nicholas R. Hutzler3* Ultracold polyatomic molecules are promising candidates f...
10.1126_science.adg8116
RES EARCH MPOX APOBEC3 deaminase editing in mpox virus as evidence for sustained human transmission since at least 2016 Áine O’Toole1*, Richard A. Neher2, Nnaemeka Ndodo3, Vitor Borges4, Ben Gannon5, João Paulo Gomes4,6, Natalie Groves7, David J. King8, Daniel Maloney1, Philippe Lemey9, Kuiama Lewandowski5, Nicholas...
10.1126_science.adg2657
RES EARCH CHIRAL MATERIALS A magnetic assembly approach to chiral superstructures Zhiwei Li†, Qingsong Fan, Zuyang Ye, Chaolumen Wu, Zhongxiang Wang, Yadong Yin* Colloidal assembly into chiral superstructures is usually accomplished with templating or lithographic patterning methods that are only applicable to mate...
10.1126_science.adg0059
RES EARCH IONTRONICS Cascade-heterogated biphasic gel iontronics for electronic-to-multi-ionic signal transmission Weipeng Chen1,2†, Linxin Zhai3†, Suli Zhang4,5†, Ziguang Zhao1,2†*, Yuhao Hu1,2, Yun Xiang1, Huirong Liu4,5, Zhiping Xu3, Lei Jiang1,2, Liping Wen1,2* Currently, electronics and iontronics in abiotic-b...
10.1126_science.adg9232
RES EARCH ORGANOMETALLICS Oxidative addition of an alkyl halide to form a stable Cu(III) product Yongrui Luo1†, Yuli Li1†, Jian Wu1, Xiao-Song Xue1*, John F. Hartwig2*, Qilong Shen1* The step that cleaves the carbon-halogen bond in copper-catalyzed cross-coupling reactions remains ill defined because of the multipl...
10.1126_science.adg9091
RES EARCH R E S E A R C H A R T I C L E S U M M A R Y ◥ ANTIMICROBIAL PROTEINS The mechanism of the phage-encoded protein antibiotic from FX174 Anna K. Orta†, Nadia Riera†, Yancheng E. Li, Shiho Tanaka, Hyun Gi Yun, Lada Klaic, William M. Clemons Jr.* INTRODUCTION: As part of their life cycle, viruses must escape...
10.1126_science.adh0993
RES EARCH PLASTIC UPCYCLING Chemical upcycling of polyethylene, polypropylene, and mixtures to high-value surfactants Zhen Xu1†, Nuwayo Eric Munyaneza1†, Qikun Zhang2, Mengqi Sun1, Carlos Posada1, Paul Venturo1, Nicholas A. Rorrer3,4, Joel Miscall3,4, Bobby G. Sumpter5*, Guoliang Liu1,6* Conversion of plastic waste...
10.1126_science.adg9500
RES EARCH QUANTUM SENSING Improving metrology with quantum scrambling Zeyang Li ( Roman Schmied5, Soonwon Choi4, Mikhail Lukin2, Edwin Pedrozo-Peñafiel1, Vladan Vuletić1* )1, Simone Colombo1, Chi Shu1,2, Gustavo Velez1,3, Saúl Pilatowsky-Cameo4, Quantum scrambling describes the spreading of information into many d...
10.1126_science.adh1411
RES EARCH STRUCTURAL BIOLOGY Translation dynamics in human cells visualized at high resolution reveal cancer drug action Huaipeng Xing1,2, Reiya Taniguchi1, Iskander Khusainov1, Jan Philipp Kreysing1,3, Sonja Welsch4, Beata Turonˇová1, Martin Beck1,5* Ribosomes catalyze protein synthesis by cycling through various ...
10.1126_science.adh2888
incarcerations that occurred in the country (16). Although homicide and incarceration trends are imperfect because they do not discriminate between offenses that occurred specifically in the context of organized crime, they can be used to estimate cartels’ violence capacity and the state’s incapacitation against them. ...
10.1126_science.adh3428
RES EARCH R E S E A R C H A R T I C L E ◥ COMPARATIVE COGNITION Songbird species that display more-complex vocal learning are better problem-solvers and have larger brains Jean-Nicolas Audet1,2*, Mélanie Couture1,3, Erich D. Jarvis1,2,3,4* Complex vocal learning, a critical component of human spoken language, has...
10.1126_science.adh2526
Corrected 5 January 2024. See full text. RES EARCH ATMOSPHERES Iodine oxoacids enhance nucleation of sulfuric acid particles in the atmosphere Xu-Cheng He1,2,3*, Mario Simon4, Siddharth Iyer5, Hong-Bin Xie6*, Birte Rörup1, Jiali Shen1, Henning Finkenzeller7,8, Dominik Stolzenburg1,9, Rongjie Zhang6, Andrea Baccarin...
10.1126_science.adh4419
RES EARCH R E S E A R C H A R T I C L E ◥ INORGANIC CHEMISTRY Diberyllocene, a stable compound of Be(I) with a Be–Be bond Josef T. Boronski*, Agamemnon E. Crumpton, Lewis L. Wales, Simon Aldridge* The complex diberyllocene, CpBeBeCp (Cp, cyclopentadienyl anion), has been the subject of numerous chemical investiga...
10.1126_science.adg6881
RES EARCH METALENSES Extreme ultraviolet metalens by vacuum guiding Marcus Ossiander1*†, Maryna Leonidivna Meretska1†, Hana Kristin Hampel2†, Soon Wei Daniel Lim1, Nico Knefz2, Thomas Jauk2, Federico Capasso1*, Martin Schultze2* Extreme ultraviolet (EUV) radiation is a key technology for material science, attosecon...
10.1126_science.adg7883
RES EARCH STRUCTURAL BIOLOGY Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription Max E. Wilkinson1,2,3,4,5, Chris J. Frangieh1,2,3,4,5,6, Rhiannon K. Macrae1,2,3,4,5, Feng Zhang1,2,3,4,5* Non–long terminal repeat (non-LTR) retrotransposons, or long interspersed nuclear element...
10.1126_science.adh0059
RES EARCH MOLECULAR BIOLOGY Structural basis for inactivation of PRC2 by G-quadruplex RNA Jiarui Song1,2,3, Anne R. Gooding1,2,3, Wayne O. Hemphill1,2,3, Brittney D. Love4,5,6, Anne Robertson4,5,6,7, Liqi Yao1, Leonard I. Zon4,5,6,7, Trista E. North4,5,6, Vignesh Kasinath1*, Thomas R. Cech1,2,3* Polycomb repressive...
10.1126_science.adh5206
RES EARCH NEUROSCIENCE Volitional activation of remote place representations with a hippocampal brain–machine interface Chongxi Lai1*†‡, Shinsuke Tanaka1†‡, Timothy D. Harris1, Albert K. Lee1,2* The hippocampus is critical for recollecting and imagining experiences. This is believed to involve voluntarily drawing f...
10.1126_science.adh5315
RES EARCH QUANTUM OPTICS Quantum vortices of strongly interacting photons Lee Drori†, Bankim Chandra Das†, Tomer Danino Zohar, Gal Winer, Eilon Poem, Alexander Poddubny, Ofer Firstenberg* Vortices are topologically nontrivial defects that generally originate from nonlinear field dynamics. All-optical generation of ...
10.1126_science.adg8802
RES EARCH CELLULAR IMMUNOLOGY Perforin-2 is a pore-forming effector of endocytic escape in cross-presenting dendritic cells Pablo Rodríguez-Silvestre1, Marco Laub1, Patrycja A. Krawczyk1, Alexandra K. Davies2†, Julia P. Schessner2, Reejuana Parveen1, Benjamin J. Tuck1,3, William A. McEwan3, Georg H. H. Borner2, Patr...
10.1126_science.adh1331
RES EARCH GEOPHYSICS Tremor signals during fluid injection are generated by fault slip Shankho Niyogi1*, Abhijit Ghosh1, Abhash Kumar2, Richard W. Hammack2 Seismic tremor signals, also known as long-period, long-duration signals, have been reported in several locations where fluid injection for enhanced oil and gas...
10.1126_science.adh7670
RES EARCH FERROELECTRICS Atomic-scale polarization switching in wurtzite ferroelectrics Sebastian Calderon V1, John Hayden2, Steven M. Baksa2, William Tzou1, Susan Trolier-McKinstry2, Ismaila Dabo2, Jon-Paul Maria2, Elizabeth C. Dickey1* Ferroelectric wurtzites have the potential to revolutionize modern microelectr...
10.1126_science.adh5339
RES EARCH ENZYMOLOGY Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity Victor S. Lelyveld1,2, Ziyuan Fang1,2,3, Jack W. Szostak1,2,3,4,5,6* A DNA polymerase with a single mutation and a divalent calcium cofactor catalyzes the synthesis of unnatural N3′→P5′ phosphoramidate (NP) bonds to fo...
10.1126_science.adh8160
RES EARCH BIOCHEMISTRY Structure of a ribonucleotide reductase R2 protein radical Hugo Lebrette1,2*†, Vivek Srinivas1†, Juliane John1, Oskar Aurelius1,3, Rohit Kumar1, Daniel Lundin1, Aaron S. Brewster4, Asmit Bhowmick4, Abhishek Sirohiwal1, In-Sik Kim4, Sheraz Gul4, Cindy Pham4, Kyle D. Sutherlin4, Philipp Simon4, ...
10.1126_science.adh8830
RES EARCH HERBIVORY Plant size, latitude, and phylogeny explain within-population variability in herbivory The Herbivory Variability Network*† Interactions between plants and herbivores are central in most ecosystems, but their strength is highly variable. The amount of variability within a system is thought to inf...
10.1126_science.adh8190
RES EARCH BIOPHYSICS MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels Zijing Zhou1,2†, Xiaonuo Ma3,4†, Yiechang Lin5, Delfine Cheng1,2, Navid Bavi6, Genevieve A. Secker7, Jinyuan Vero Li1,2, Vaibhao Janbandhu1,2, Drew L. Sutton7,8, Hamish S. Scott7,8,9, Mingxi Yao10, Richard P. Harvey1,2,11...
10.1126_science.adi1071
Post date 6 June 2024 Retraction On 8 December 2023, Science published the Research Article “Drought sensitivity in mesic forests heightens their vulnerability to climate change” (1). In January 2024, Stefan Klesse, William Anderegg, John Abatzoglou, and Margaret E. K. Evans alerted the authors to errors in an R scri...
10.1126_science.adi1563
RES EARCH 3D PRINTING Self-enhancing sono-inks enable deep-penetration acoustic volumetric printing Xiao Kuang1†, Qiangzhou Rong2†, Saud Belal2†, Tri Vu2, Alice M. López López1, Nanchao Wang2, Mehmet Onur Arıcan1, Carlos Ezio Garciamendez-Mijares1, Maomao Chen2, Junjie Yao2*, Yu Shrike Zhang1* Volumetric printing, ...
10.1126_science.ade4245
RES EARCH QUANTUM SIMULATION Direct observation of nonlocal fermion pairing in an attractive Fermi-Hubbard gas Thomas Hartke*, Botond Oreg, Carter Turnbaugh, Ningyuan Jia, Martin Zwierlein The Hubbard model of attractively interacting fermions provides a paradigmatic setting for fermion pairing. It features a cross...
10.1126_science.adf8999
resonant electric dipole-dipole coupling for coherent exchange of rotational angular mo- mentum between pairs of laser-cooled CaF molecules individually trapped in optical twee- zers. With the ability to tune the angle of the molecular quantization axis in the lab frame, our system realizes both ferromagnetic and antif...
10.1126_science.adi2436
RES EARCH MOLECULAR BIOLOGY Human POT1 protects the telomeric ds-ss DNA junction by capping the 5′ end of the chromosome Valerie M. Tesmer, Kirsten A. Brenner, Jayakrishnan Nandakumar* Protection of telomeres 1 (POT1) is the 3′ single-stranded overhang-binding telomeric protein that prevents an ataxia telangiectasi...
10.1126_science.adh9059
RES EARCH HOST-GUEST CHEMISTRY Disequilibrating azobenzenes by visible-light sensitization under confinement Julius Gemen1, Jonathan R. Church2, Tero-Petri Ruoko3, Nikita Durandin3, Michał J. Białek4, Maren Weißenfels1, Moran Feller1, Miri Kazes1, Magdalena Odaybat5, Veniamin A. Borin2, Rishir Kalepu1, Yael Diskin-P...
10.1126_science.adf9725
RES EARCH NEUROSCIENCE Wide-field fluorescence lifetime imaging of neuron spiking and subthreshold activity in vivo Adam J. Bowman1*, Cheng Huang2,† Mark J. Schnitzer2,3,4, Mark A. Kasevich1* The development of voltage-sensitive fluorescent probes suggests fluorescence lifetime as a promising readout for electrical...
10.1126_science.adi1826
RES EARCH FISHERIES Large females connect Atlantic cod spawning sites Esben Moland Olsen1,2*, Ørjan Karlsen3, Jon Egil Skjæraasen3 The Earth’s ecosystems are increasingly deprived of large animals. Global simulations suggest that this downsizing of nature has serious consequences for biosphere functioning. However,...
10.1126_science.adi6354
RES EARCH PHYSICS Ergodicity breaking in rapidly rotating C60 fullerenes Lee R. Liu1,2*, Dina Rosenberg1,2, P. Bryan Changala1,2†, Philip J. D. Crowley3, David J. Nesbitt1,2,4, Norman Y. Yao3, Timur V. Tscherbul5, Jun Ye1,2* Ergodicity, the central tenet of statistical mechanics, requires an isolated system to expl...
10.1126_science.adi1024
RES EARCH NEUROSCIENCE Climbing fiber multi-innervation of mouse Purkinje dendrites with arborization common to human Silas E. Busch1 and Christian Hansel1* Canonically, each Purkinje cell (PC) in the adult cerebellum receives only one climbing fiber (CF) from the inferior olive. Underlying current theories of cere...
10.1126_science.adi8237
RES EARCH R E S E A R C H A R T I C L E S U M M A R Y ◥ NEUROSCIENCE Associative and predictive hippocampal codes support memory-guided behaviors Can Liu†, Ralitsa Todorova†, Wenbo Tang, Azahara Oliva, Antonio Fernandez-Ruiz* INTRODUCTION: The brain generates models of the environment that are used to guide flexi...
10.1126_science.adj0040
RES EARCH ORGANIC CHEMISTRY Multiplicative enhancement of stereoenrichment by a single catalyst for deracemization of alcohols Lu Wen†, Jia Ding†, Lingfei Duan†, Shun Wang, Qing An, Hexiang Wang, Zhiwei Zuo* Stereochemical enrichment of a racemic mixture by deracemization must overcome unfavorable entropic effects ...
10.1126_science.adi8474
RES EARCH MACHINE LEARNING Backpropagation-free training of deep physical neural networks Ali Momeni1, Babak Rahmani2, Matthieu Malléjac1, Philipp del Hougne3, Romain Fleury1* Recent successes in deep learning for vision and natural language processing are attributed to larger models but come with energy consumptio...
10.1126_science.adk1111
RES EARCH GLYCOSYLATION Palladium catalysis enables cross-coupling–like SN2-glycosylation of phenols Li-Fan Deng1†, Yingwei Wang2†, Shiyang Xu1, Ao Shen1, Hangping Zhu1, Siyu Zhang1, Xia Zhang1, Dawen Niu1* Despite their importance in life and material sciences, the efficient construction of stereo-defined glycosid...
10.1126_science.adj5328
RES EARCH PHYSICAL CHEMISTRY Direct observation of chirality-induced spin selectivity in electron donor–acceptor molecules Hannah J. Eckvahl1†, Nikolai A. Tcyrulnikov1†, Alessandro Chiesa2†, Jillian M. Bradley1, Ryan M. Young1, Stefano Carretta2*, Matthew D. Krzyaniak1*, Michael R. Wasielewski1* The role of chirali...
10.1126_science.adj6491
RES EARCH INORGANIC CHEMISTRY An all-metal fullerene: [K@Au12Sb20]5− Yu-He Xu1, Wen-Juan Tian2, Alvaro Muñoz-Castro3, Gernot Frenking4,5, Zhong-Ming Sun1* The C60 fullerene molecule has attracted tremendous interest for its distinctive nearly spherical structure. By contrast, all-metal counterparts have been elusiv...
10.1126_science.adi3038
RES EARCH VOLCANOLOGY Fast and destructive density currents created by ocean-entering volcanic eruptions Michael A. Clare1*†, Isobel A. Yeo1*†, Sally Watson2, Richard Wysoczanski2, Sarah Seabrook2, Kevin Mackay2, James E. Hunt1, Emily Lane2, Peter J. Talling3, Edward Pope3, Shane Cronin4, Marta Ribó5, Taaniela Kula6...
10.1126_science.adj5438
RES EARCH PHOTONICS Ultrafast mode-locked laser in nanophotonic lithium niobate Qiushi Guo1,2,3*, Benjamin K. Gutierrez4, Ryoto Sekine1, Robert M. Gray1, James A. Williams1, Luis Ledezma1,5, Luis Costa1, Arkadev Roy1, Selina Zhou1, Mingchen Liu1, Alireza Marandi1,4* Mode-locked lasers (MLLs) generate ultrashort pul...