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Parametric Cell Shapes (PCS) renders 256×256-pixel, 8-bit brightfield crops at 0.158 µm/px using Fourier descriptors and Perlin noise. Each image’s outline and texture are controlled by a 10-dimensional parameter vector that adjusts deviation, roughness, axis lengths, orientation, texture scale/intensity/contrast, and ring width/intensity. Optical point-spread (ring) effects and sensor noise are matched to REM-I instrument statistics. Three one-parameter grids (shape, texture, width) with 300 random samples per level enable systematic probing of embedding resolution. |