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treelevel biomass maps for africa | trees outside forests make up more than one quarter of the tree cover in africa but there is currently a lack of efficient and reliable monitoring systems for trees outside forests previous research suggests that most forest and landscape restoration flr is occurring outside of contiguous forests particularly in agrofo... |
doctoral training programme in functional advanced materials towards a better future | docfam doctoral training programme in functional advanced materials towards a better future is a new excellent doctoral programme for the recruitment of 26 excellent doctoral researchers led by csic through icmab it builds on the success and positive outcomes from the original docfam programme by providing a new dimens... |
innovative 5r solutions for textile integrated circular economy | solstice aims at demonstrating 4 replicable systemic solutions for the territorial deployment of the circular economy cec for the major industrial sector of textiles 62mt producedyear all steps of waste prevention and management will be included in a 5r strategy refusereduce reuse repair repurpose recycle the solutions... |
modulation of valencebased learning and behavior a closedloop approach in the primate amygdala | the primate amygdala is a neural hub that processes computations for learning and memory specifically when learning involves emotional motivational and reinforcementbased signals this requires it to remain highly adaptive for changes in valence of environments and stimuli failures of such computations can lead to malad... |
migrants protests how the borders of citizenship are conceived mobilized and constructed by migrants farm workers protests | migrants workers exploitation in several fields of production is one of the most dramatic and serious aspects of our societies and at the same time one of the not enough explored discussed voiced nevertheless hard structural and subjective conditions migrants workers as several recent case show in italy and worldwide p... |
the making of local legal cultures under rome a view from the margins | law and order were romes vehicles for displaying its imperial authority and supremacy over nonroman subjects however rome did not fill a legal vacuum rather it competed with established legal practices among communities in the greek east these communities took pride in their legal traditions as they were being absorbed... |
social and technological innovation factory for lowcarbon and circular industrial value chains | the sotecin factory social and technological innovation factory for lowcarbon and circular industrial value chains goal is to connect industry with society in a community of missionoriented social innovators to support social entrepreneurs in their drive to increase the circularity of key product value chains and to pr... |
edible lasers for safety and authentication of food and pharmaceuticals | the goal of ediblelasers is to make microlasers entirely out of edible materials and explore their potential for barcoding and sensing in food pharmaceuticals and beyond in the ongoing erc starting grant celllasers we have developed several lasers made out of biocompatible and biological materials and implanted them in... |
scalable method for synthesis of multifunctional colloidal inks for superconductors | global warming is one of the main challenges that society is currently facing it involves a major change of the energy paradigm to drastically reduce co2 emissions high temperature superconductivity presents a huge interest worldwide for its opportunities for cleantech energy as superconductors allow energy harvesting ... |
nanobiological contrast agent platform for mri imaging | nanoimaging proposes the elucidation of the potential of a metalprotein hybrid nanostructure as a platform for the development of tissuespecific positive magnetic resonance imaging mri contrast agents this proposal builds on the large demand for mri examinations worldwide the health concerns raised by available contras... |
compatibility assessment of nonsteel metallic distribution gas grid materials with hydrogen | green hydrogen is gaining moment across europe as feedstock fuel or energy carrier and storage as solid actions are needed to reach carbon neutrality by 2050 hydrogen has many possible applications across industry transport energy and building sectors and therefore local gas grids across europe are working hard to get ... |
smart aware integrated wind farm control interacting with digital twins iconic | iconic aims to develop innovative physical and digital tools to achieve fundamental breakthroughs for the integrated control of wind farms considering the whole physical system at farm turbine and component levels in particular the complex aerodynamic interactions among turbines iconic aims to increase farmwide power p... |
lightcure light for double specificity and efficacy without burden | congenital hyperinsulinism chi is a group of rare diseases of newborns and infants with functionally defective nonneoplastic betacells that cause hypoglycemia and severe morbidity through oversecretion of insulin chi is a major cause of hypoglycemic brain injury with intellectual disability epilepsy and cerebral palsy ... |
systematic analyses and rational engineering of fast co2 fixation pathways in living cells | biological co2 fixation is the primary process responsible for biomass and food production and a key player in the atmospheric co2 balance almost all biological co2 fixation is caried out by a single pathway the calvin cycle despite the dominance of this pathway in nature it seems relatively inefficient due to high ene... |
fate of reduced organic sulfur | arctic suffers of the global warming and as a consequence ground and surface waters are more and more mixed increasing microbial activities because ros are present in all living organisms as amino acids ie cysteine and methionine increasing microbial activities induce increasing production of reduced organic sulfur ros... |
heterogeneous integrated shortwave infrared colloidal quantum dot lasers | irqual addresses the critical need for compact integrated lasers operating in the shortwave infrared swir spectrum 13 25 m for diverse applications such as consumer electronics automotive iot and arvr specifically lasers in the eyesafe window around 14 m and 2 m are crucial for lidar systems 3d face recognition and env... |
model theory locally compact groups and solution of hilberts 5th problem | the main goal of the project is to apply advanced techniques from the model theory a branch of mathematical logic to the class of locally compact groups arising from the solution of hilberts 5th problem so at the end to the class of lie groups to answer the following question how much geometry can model theory recogniz... |
strengthening the integrated approach of holistic impact assessments for safe and sustainable by design plastic value chain | analyst aims to accelerate the transition towards a safer and more sustainable industrial value chain while encouraging and expanding the existing knowledge on the safe and sustainable by design ssbd framework in this vein the project develops and implements 3 different innovations figure 1 innovation 1 i1 analystbox c... |
the best way to know your health we have integrated a medical device into a toilet allowing people to take an autonomous exam related to several health parameters with simplicity and regularity | abluteis the best way to know your health by integrating a urinalysis device into a waterefficient toilet people can take exams with the simplicity of using a bathroom regular screening is the most reliable method to early detect diseases ablute delivers simplicity to health examination fostering regularity the equipme... |
the global south in the age of early industrial capitalism commodity frontiers and social transformations 18161870 | our lives would be unthinkable without the production of millions of tons of cotton sugar palm oil or soy all these commodities are obtained at the lowest possible price with often detrimental consequences for people and nature the scale of the resulting environmental crises may be something of recent making its mechan... |
cell line engineering for imporved fertility treatment | kyronbio is a female led biotech company on a mission is to unclog bottlenecks in therapeutic protein production allowing better drugs to reach patients we are using synthetic biology to engineer mammalian cell lines for improved bioproduction harnessing highly efficient enzymes from diverse life forms our preliminary ... |
a lightweight software stack and synergetic metaorchestration framework for the next generation compute continuum | the vision of nephele is to enable the efficient reliable and secure endtoend orchestration of hyperdistributed applications over programmable infrastructure that is spanning across the compute continuum from cloudtoedgetoiot removing existing openness and interoperability barriers in the convergence of iot technologie... |
worlwide hydrological largescale database | vortexio offers an innovative and intelligent service for monitoring hydrological surfaces using insitu remote sensing instruments based on compact lightweight altimeter inspired from satellite technology the microstations it provides in real time with a high frequency and accuracy hydrometeorological parameters water ... |
morphologically linked old irish resource | the aim of molormorphologically linked old irish resourceis to make old irish distributed lexical resources interact by using stateoftheart data models and lexicographic standards based on the linguistic linked open data llod principles on the basis of the 8thcentury old irish würzburg glosses molor will fully exploit ... |
green selfpowered neuromorphic processing engines with integrated visual and functional sensing | todays internetofthings iot incorporates a complex distributed network of wireless sensors and processors connected to the cloud these platforms and their dataprocessing needs are creating a stronger and stronger demand for energy that is not sustainable at the same time the increasing consumers demand for iot electron... |
multifunctional fibrereinforced plastic composites with mxene layers | fibrereinforced plastic composites frpc are widely used in advanced fields such as aviation shipbuilding wind energy etc frpc structures during exploitation lose loadbearing capacity because of local damage icing water absorption and other factors the specific objective of the miracles fundamental research is frpc with... |
self healing soft materials for sustainable products | the shinto project aims to disrupt the soft robotics market by creating a new market for selfhealing structural components introducing autonomous damage detection and healing in intelligent soft robots the current field is driven by a high adoption of soft grippers that ensure safe operation for collaborative robots in... |
extracellular vesicles as mediators of premetastatic niche formation in melanoma | every 2 minutes someone in the world is diagnosed with melanoma so by the time you read this application dozens of new melanoma cases will be detected beyond its growing incidence cutaneous melanoma is the most aggressive type of skin cancer and notorious for its high metastatic propensity which constitutes the primary... |
investigating microbial colonization and removal on dynamic patterned surfaces | microbes have remarkable capabilities to attach to surfaces of natural and artificial systems eventually leading to the formation of biofilms and associated chronic and persistent infections it is extremely appealing to understand how bacteria interact with three dimensional surface topographies and how to design smart... |
2dimensional phasesensitive ultrafast spectroscopy unravelling photoinduced reactions by multidimensional raman | we propose the construction and development of a visibleultraviolet uv twodimensional resonance raman 2dr setup with phasesensitive detection to tackle ultrafast chemical physical and biological processes lightinduced reactions cover a broad range of phenomena from screening of photodamage in skin upon uv irradiation t... |
revolutionary refurbishment for an efficient and ecofriendly hydropower | the revhydro project aims to enhance the efficiency flexibility and sustainability of existing hydropower plants through the design and validation of flow control devices specifically the proposed flow control devices located in the runner and draft tube extend the operating range of turbines reduce fatigue and enhance... |
elucidating the role of biomolecular condensation in meiotic dna doublestrand break formation | meiosis universally relies on the formation of dna doublestrand breaks dsb to initiate a genomewide recombination program that promotes genetic diversity and is required to produce chromosomallybalanced haploid gametes dsb formation is catalyzed by spo11 which in acts in conjunction with nine essential partners in yeas... |
sensorimotor integration motor planning and learning in fly | we are constantly learning new motor skills throughout our life whether riding a bicycle or playing an instrument motor learning relies on a calibration between sensory signals and internal motor information saccadic adaptation the recalibration of fast eye rotations induced by visual error signals has helped develop k... |
biodiversity building blocks for policy | the world is changing rapidly climate change land use change pollution and natural resource exploitation are creating a global crisis for biodiversity whose magnitude and dynamics are hard to quantify decision makers at all levels need uptodate information from which to evaluate policy options for this reason rapid rel... |
precision diagnostics for predicting therapy response to bispecific antibodies | immunotherapies have revolutionized cancer treatment by utilizing the patients immune system offering hope for treating a wide range of diseases however challenges such as therapy resistance poor response rates and high costs remain precision diagnostics that accurately identify patients likely to benefit from specific... |
realtime monitoring of deep crustal mass redistribution for timely prediction of earthquake using integrated geodetic gravity and seismic data | the proposed remcrumr research is a concerted effort designed to get as close as possible to being able to predict the time to an accuracy of 1 week and location to a accuracy of 100 x 100 km of occurrence of imminent devastating earthquakes m5 based on lithosphere strain and upper mantle dynamics it makes use of a mul... |
hybrid integration of alkaline niobate tantalate films for advanced photonic and piezoelectric devices | the hina project proposes to consider the hybrid integration of alkaline niobatetantalate thin films materials with the highest known experimentally measured electrooptic nonlinear piezoelectric elastooptic coefficients in photonic and acoustic devices for advanced semiconductor photonics platforms the final goal of th... |
engineering catalytic membraneless organelles for co2 fixation | in recent years membraneless organelles were shown to be intracellular liquid like condensates formed through phase separation following their discovery they have been found across all kingdoms of life for some of these organelles a crucial role in cellular physiology has been determined while for many others their tru... |
a comprehensive approach to value transmission in the digital age | the eu aims to promote common values and beliefs among members classic research establishes parents as the main role models for such transmission however children today learn values from new role models such as social media influencers smis users who share content to acquire followers the project will construct a compr... |
bringing molecular photomagnets to light achieving magnets through visible light excitation at room temperature | visible light provided by the sun is the cleanest energy source one could ever imagine harvesting it is crucial for further development of science and technology as well as for reducing the ecological footprint of humanity the efficient use of the visible spectrum of the sun can take many forms and the direct photoexci... |
network trajectory based operations | the network trajectory based operations network tbo project proposes to validate tbo sesar solutions covers all aspects of trajectory management processes involving but not limited to network actors it covers both planning and execution phases the proposed sesar solutions with an indication of the technology readiness ... |
tax morale and social desirability bias examining the shadow economy experimentally | it is believed that high tax morale delivers higher tax compliance however it can also foster social desirability bias when respondents feel pressure to provide morally accepted even if untrue answers this research project offers to understand how tax morale fosters social desirability bias and seeks ways to reduce the... |
multilingual flexible neurosymbolic language generation | the core aim of the mflens multilingual flexible neurosymbolic language generation project is to explore the extent to which combining the strengths of neural and symbolic grammarbased natural language generation nlg systems is possible we will build flens generators that i exploit grammarbased system aspects to addres... |
trusted extremely precise mapping and prediction for emergency management | tema will greatly improve natural disaster management ndm eg for wildfires floods by automating precise semantic 3d mapping and disaster evolution prediction to achieve ndm goals in nearrealtime it will analyze and fuse many heterogeneous extreme data sources smart drone and insitu sensors remote sensing data topograph... |
implementation of activities described in the roadmap to fusion during horizon europe through a joint programme of the members of the eurofusion consortium | eurofusions updated fusion research roadmap aims to acquire the necessary knowledge to start constructing a demonstration fusion power plant demo five years after iter is in fullpower operation demo will deliver fusion electricity to the grid early in the second half of the century the roadmap has been articulated in e... |
celestial hierarchy in arabic translation | chart aims at investigating how arabic christianity living in a predominantly islamic environment assimilated its own foundational religious heritage through a momentous translation process from greek into arabic the case study is chosen among the unpublished arabic translations of the mysterious christian theologian k... |
network of excellence in digital technologies and ai solutions for electromechanical and power systems applications | digitalization is the key to fighting climate change and achieving the objectives of the european green deal while contributing to the green energy transition energy efficient buildings sustainable transportation and industrial digital transformation digital technologies and ai solutions can deliver operational efficie... |
next generation hpcqc in silico drug discovery platform for de novo design | atlas is a powerful in silico drug discovery platform leveraging the latest advances in highperformance and quantum computing the platform is the result of decades of research by leading experts in molecular dynamics the technology is grounded on over 100 peerreviewed papers and two erc grants our beta code has gathere... |
advancing understanding of cumulative impacts on european marine biodiversity ecosystem functions and services for human wellbeing | actnow advances the stateoftheart in understanding and forecasting of the cumulative impacts of climate change and interacting drivers on marine systems the program provides solutions options to halt the loss of biodiversity to restore and protect habitats and ecosystem processes and to safeguard the contributions of m... |
controlling the flow of attention transition dynamics of attention and distraction across external and internal domains | we often choose to distract our minds either externally eg looking at our phone or internally eg thinking about weekend plans it is currently not clear how when or why we choose to become distracted nor do we have a mechanistic understanding of flow states in which there is minimal distraction this is a pressing issue ... |
intelligent asset management platform for hydropower operation and maintenance | the iamphydro project will improve the digital operation of existing plants through the development of 6 expected results r which will collectively form iamp a novel intelligent asset management platform see result r5 in fig 1 encompassing secure open and transparent data sharing protocols r4 and three novel digital so... |
biophysical genetic design automation technology | advances in our capabilities to program synthesize and modify dna has led to a surge in the field of synthetic biology various gene circuits have been proposed and designed in various organisms for application domains ranging from biomedicine over biotechnology to biomaterials our current bottleneck is not anymore our ... |
optical and wireless sensors networks for 6g scenarios | in the optical and wireless sensors networks for 6g scenarios owin6g project key industry and academic stakeholders are brought together with the aim of developing a structured european training programme tp in optical technologies to facilitate disruptive wireless sensor applications within sixthgeneration 6g networks... |
reinforcement learning to improve proofautomation in theorem proving | developing generic proof automation methods for interactive theorem provers itps is challenging but valuable applications range from performance improvements in the verification of safetycritical systems to the certification of famous long and hardtoprove theorems we propose using recently successful reinforcement lear... |
the stress granule machinery controls metabolic signalling through mtor at steadystate | mtor kinase is an oncogenic master regulator of metabolism and cell growth and is known to reside in two multiprotein complexes upon stress mtor is inhibited by stress granules sgs which recruit mrnas and signaling factors to promote survival current work largely addresses the functions of sg proteins under stress focu... |
greenrubber sustainable production of natural rubber using yeast | natural rubber is a very important and widely used industrial raw material which cannot be replaced by other equivalents because of its unique properties eg durability and insulation synthetic rubber produced by petrochemicals is not only detrimental to the environment but also cannot replace natural rubber due to its ... |
european doctoral programme for smart urban coastal sustainability | the eudocs for smucs programme is a european doctoral programme designed to train 17 phd students based on cotutelles between la rochelle universit lruniv and its partners from the euconexus european alliance and beyond based on a challengedriven approach of research and education it addresses the societal challenges r... |
utility and unique chemistry of homoallylic amines with a difluoromethyl and fluoro substituted stereogenic carbon | organofluorine compounds are scarce in natural products but they are central to therapeutic science agrochemical development and materials research incorporation of fluorine atoms within an organic molecule can have profound effects on pharmacokinetic and pharmacodynamic properties enantiomerically enriched fluoro amin... |
kinetic exponent network analysis | significant efforts are underway in europe to reshore the synthesis of active chemical ingredients apis to ensure the safety and availability of medicine for its citizens this goes hand in hand with innovations and process intensification for example doing multiple chemical reaction steps in one go andor by using conti... |
citynaturebased solutions integration to local urban infrastructure protection for a climate resilient society | nbsinfra supports the enhancement of the local urban critical infrastructures protection against natural and manmade hazards through the naturebased solutions nbs codesign and cocreation for a climate change resilient society nbsinfra will demonstrate that the naturebased solutions are a technically viable for the prot... |
preclinical validation of a novel gene therapy for a rare disease in nonhuman primates integrative approach to the cmc scaleup process validation of a gene therapy product for friedreich ataxia | founded in 2018 biointaxis is an academic spinoff company established by a team of researchers lead by a woman scientist from the research institute germans trias i pujol igtp benefiting from extensive knowhow in the identification of genes biomarkers and translational mechanisms underlying neurodegenerative disorders ... |
mitigating diversity biases of ai in the labor market | artificial intelligence ai is increasingly used in the employment sector to manage and control individual workers one type of ai is natural language processing nlp based tools that can analyze text to make inferences or decisions a recent sage study found that 24 of companies used ai for hiring purposes in an employmen... |
foundations of generalization | arguably the most crucial objective of learning theory is to understand the basic notion of generalization how can a learning agent infer from a finite amount of data to the whole population todays learning algorithms are poorly understood from that perspective in particular best practices such as using highly overpara... |
boosting research capabilities of romanian cloud microphysics centre | as the only airborne cloud research platform holder in eastern europe incas is in the perfect position to be a wellknown rd organisation that obtain urgently needed data sets process and interpret them in order to improve future climate projections however to date a lack of presenting these capabilities has left incas ... |
synergies for green transformation of inland and coastal shipping | the extent of shipping decarbonization and reduction of air pollutant emissions remains limited despite the rapid development of greening technologies this is particularly valid for existing inland vessels and coastal shipsa large scale retrofit of the fleet would accelerate the greening transformation however there is... |
antimicrobial nanocoatings for hospital textiles to prevent the spread of healthcare associated infections | the main objective of nanoprotect is to develop innovative antibacterial antifungal antiviral and antibiofilm 4a nanoenabled coatings for medical textiles upholstery fabrics and personal protective equipment ppe which would be susceptible to pathogens contamination in hospitals this proposal will focus on designing a p... |
interplay of charge and energy transfer in single molecules | in the pursuit to mimic highly efficient natural processes like photosynthesis in optoelectronic devices moleculebased architectures are becoming increasingly important in reducing costs and improving energy efficiency in these processes intermolecular charge and energy transfer are intimately linked however how exactl... |
biologically plausible transformers integrating topdown and bottomup signals in the primary vision system for computationally efficient deep learning | deep learning dl has recently achieved remarkable success due to the continuous growth in model sizes however this growth has led to increased energy consumption hardware implementation of digital dl can help reduce energy usage but the von neumann architecture of current dl has hindered its practical realization in co... |
to a fair inclusive circular and healthy cities valorisation of phosphogypsum wastes into commercial products through sustainable and circular processes | ficfighters is a local democracy project it is the search for new economic models deliberately agreed to manage of waste that harms the natural and cultural heritage it is a space for discussion on the adoption of alternatives for wastes that has been accumulating near our cities for decades the project will involve di... |
transformation towards longterm sustainability beyond sustainable development goals | countries are not on track to meet the 2030 agenda for sustainable development that comprises 17 sustainable development goals sdgs and 169 targets to be achieved by 2030 although sdgs aim to shift the world onto a sustainable and resilient path countries are not yet able to make transformative changes for longterm sus... |
biocultural roots of diversity and inequality in mexico 500 years of mestizo stories | transatlantic contact during the 1400s ignited a series of socioeconomic political demographic and biocultural changes that irreversibly transformed the course of history in the americas with repercussions across the world but one of the most influential encounters occurred in 1519 between the mexica empire and the spa... |
hydrogen economy benefits and risks tools development and policies implementation to mitigate possible climate impacts | hydrogen is undoubtely the most talkedabout carbonfree energy vector however policymakers and citizens that are supporting hydrogen largescale penetration in the energy sector should not only be aware of the evident benefits but also of potential safety and climatic risks driven by a long term hydrogenbased economy hyd... |
demonstrator of systemic solutions for the territorial deployment of the circular economy in the trilateral chemical region with a focus on plastic waste streams quality for recycling | syschemiq will demonstrate how to migrate to a circular urbanindustrial crossborder district ie the chemelot circular hub cch in the trilateral euregio of nl be and de a circular economy action plan and a 4beur investment agenda 20202030 are available stakeholder involvement schemes are in place to allow governance wit... |
a zero waste process for producing all natural biodegradable replacement additives for synthetic polymers and microspheres | we are now discovering the harmful effects of synthetic additives plastics on the human body ecosystems due to advancements in research technology to address the problems derived from synthetic additives product formulators across the industry are actively scouting for new bio based biodegradable sustainable alternativ... |
deep learning of chemical reactions | the exploration of reactions is a central topic in chemistry compared to the success of machine learning for molecules the modeling of reactions is lagging behind especially for stereo and regioselective reactions since current efforts toward sustainable synthesis such as asymmetric organocatalysis or biocatalysis rely... |
quantum interactions in photoninduced nearfield electron microscopy | breakthroughs in electron microscopy over the past 15 years have introduced femtosecond laserdriven electron microscopes that probe matter and even hybrid lightmatter polaritons with ultrafast time resolution however such systems still mostly extract classical properties of light and matter this project will pursue the... |
tuning the electronic structure of twodimensional semiconductor junctions | lateral junctions between twodimensional 2d semiconductors are conceptually the smallest possible electronic devices this project investigates the basic physics of these systems as the type of band alignment the band bending and depletion region which are decisive parameters for any application semiconductor junctions ... |
mathematical random graph models for realworld dynamical networks | networks are all around us and hugely affect us the neurons in our brain covid19 spreading through the population or computer viruses attacking digital infrastructure via computer networks experts estimate that in the us alone their government faced costs over 137 billion dollars due to cyberattacks in 2018 insight int... |
flexible scalable and secure decentralized operating system | fluidos leverages the enormous unused processing capacity at the edge scattered across heterogeneous edge devices that struggle to integrate with each other and to coherently form a seamless computing continuum by way of a disruptive opensource paradigm that hinges upon secure protocols for advertisement and discovery ... |
a unique commercially viable recombinant manufacturing platform for human fibrinogen rhfib thrombin rhthr | we have developed the recofib platform a market first recombinant production platform for human fibrinogen rhfib thrombin rhthr using chinese hamster ovary cells cho expression technology patented upstream purification processes we are the first producer of fully intact functional recombinant fibrinogen and active thro... |
cultural heritage outreach in romance languages | the cultural heritage outreach in romance languages programme choral is naturally linked to the enlarged european alliance university unita that brings together the universities of turin and brescia italy savoie mont blanc and pau et pays de ladour france beira interior portugal timisoara and transilvania brasov romani... |
physicsbased remote touch | humans rely on their sense of touch to achieve fine manipulation tasks and interact with their surroundings however feeling the tactile properties of a remote environment remains a challenge for two main reasons first current robotic systems are rarely equipped with tactile sensing and second only forces are fed back t... |
smart subpixel urban flood mapping from open earth observation and crowdsourcing | floods are major natural disasters with severe impacts in urban areas where increasingly high population density and infrastructure together with worsening climate change trends exacerbate the risk reliable and timely monitoring is critical for resilience in terms of predisaster preparedness emergency response and post... |
signaling decoded in enhancer states a molecular basis for plasticity in development and differentiation | transcription is regulated by transcription factors tfs bound at enhancer elements located longdistances from the genes they regulate how does this account for dynamic responses to the environment via signaling canonical views invoke signal induced changes in tf expressionmodification or cofactor localization but here ... |
building capacities in innovation procurement for cities | the building capacities in innovation procurement for cities build project will roll out a number of training and capacity building actions targeted at upskilling the public procurers on the topic of innovation procurement public procurement is a powerful instrument to drive faster adoption of innovation among public s... |
the extracellular matrix as a mediator of cellcell communication in cardiovascular inflammation | cardiovascular diseases as coronary artery disease cad and its sequelae myocardial infarction mi and heart failure represent the leading cause of morbidity and mortality in industrialized and developing countries atherosclerosis is the pathology causing cad and mi both are characterized by a sterile inflammation with a... |
integrated mechanistic modelling and analysis of largescale biomedical data | modern cancer therapeutics target signalling processes within the cancer cells and the interaction of cancer and immune cells a comprehensive understanding of these signalling processes is therefore essential to identify drug targets plan clinical trials and to select suitable drugs drug combinations and drug dosages f... |
modern approach to ocular disease treatment smart lipidbased nanoparticle systems for the delivery of mrna to the ocular tissues | many severe ocular diseases lead to visual impairment and blindness in millions of patients worldwide and the number is rapidly growing in aging populations most ocular diseases are still without drug treatment and the current treatments are based on the use of small molecules and protein drugs however poor ocular abso... |
robust learning and reasoning for complex event forecasting | a growing number of applications rely on aibased solutions to carryout missioncritical tasks many of which are of temporal nature dealing with everevolving flows of information crucial for mitigating threats and taking advantage of opportunities in such domains is the ability to forecast imminent situations and critica... |
codesigning holistic forestbased policy pathways for climate change mitigation | the eu target to significantly reduce its emissions by 2030 and become climate neutral by 2050 requires new mitigation measures within all sectors clear policy pathways are needed that outline alternative trajectories for european forests and the forestbased sector towards a climateneutral and resilient society and eco... |
development of a novel machine learningbased model for multiphase flows | multiphase flow mf is the simultaneous flow of materials with two or more thermodynamic phases mf occurs in numerous settings bioengineering conventional and nuclear power plants oil and gas production and transport pharmaceutical industry combustion engines chemical industry flows inside the human body biological indu... |
wireless magnetothermal enteromodulation | gastrointestinal gi disorders affect over 40 of the world population pharmacological agents that modulate cell function and subsequently impact processes involved in such disorders suffer from limited spatiotemporal specificity and accompanying side effects despite the advances in the field of bioelectronic medicine wh... |
development of advanced thermometric nanomotors | temperature is a central concept in thermodynamics and is one of the most crucial parameters to be described in scientific and technological achievements due to the high importance of measuring this property thermometers are accounted for 80 of the sensor market and could reach 686 billion usd in 2023 according to a st... |
is there a perennial future of agriculture | perennial will investigate whether a shift from annual to perennial grain crops as the basis for food production is possible and identify the major opportunities and obstacles for such a perennial revolution since the neolithic revolution the world food system has been dominated by annual crops cereals legumes and oil ... |
trustworthy ai tools for the prediction of obesity related vascular diseases | weight problems and obesity are increasing at a rapid rate already concerning more than 436mio people in european countries obese persons have a 50 higher risk of cardiovascular disease cvd mortality and treatment costs result in a total economic burden of over 210 billion euro per year to date the prediction of the in... |
aiops framework for automated intelligent and reliable dataai pipelines lifecycle with humansintheloop and coupling of hybrid scienceguided and ai models | aidapt brings forward a datacentric mentality in ai that is effectively fused with a modelcentric scienceguided approach across the complete lifecycle of aiops by introducing endtoend automation and aibased systematic methods to support the design the execution the observability and the lifecycle management of robust i... |
computational approaches to reveal the role of astrocytes in information processing and neural networks dynamics | information about the external world is encoded in the brain through the dynamical activity of neuronal ensembles socalled neural population codes neurons however are not the only cell types making up the nervous tissue astrocytes interact with neurons at the synaptic and network level astrocytic intracellular calcium ... |
infrastructure for marine and inland water research | the overall objective of the project is to develop a virtual environment equipped with fair multidisciplinary data and services to support marine and freshwater scientists and stakeholders restoring healthy oceans seas coastal and inland waters the aquainfra virtual environment will enable the target stakeholders to st... |
ai in parkinsons disease | in response to the growing need for specialized data scientists in healthcare our initiative aims to establish an international interdisciplinary graduate school that educate the next generation of medical data scientists with a strong translational focus bridging academia and industry this is strengthened by the activ... |
pressurized efficient alkaline electrolyser peace | among the different electrolysis technologies ael is very competitive because of its low investment costs and good scalability the levelized cost of hydrogen lcoh produced by ael can be reduced by enhancing the efficiency maximal current densities and by enabling better integration with downstream processes a welltuned... |
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