pmid stringlengths 2 8 | title stringlengths 21 1.13k | abstract stringlengths 128 6k | doi stringlengths 0 72 |
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39346119 | Molecular features of NSCLC patients with liver metastasis. | Metastasis is the primary cause of lung cancer-related death. Primary cancer cells invade through the lymphatic or blood vessels to distant sites. Recently, it was proposed that lymphatic metastasis was more a hallmark of tumor aggressiveness or metastatic potential than a gateway to metastases. Therefore, the underlyi... | 10.1177/17588359241275421 |
1273048 | [Role of different regions of the hypothalamus in regulating the hypophyseal-adrenal cortex system in rats]. | The effect of electrical stimulation of various structures of the medial hypothalamus on the corticosterone level in the peripheral blood was studied in rats with preliminarily destroyed individual areas of the hypothalamus. Injury of various structures of the medial hypothalamus led the first days after the operation ... | |
15281351 | Pathology and molecular genetics of the pituitary gland in patients with the 'complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas' (Carney complex). | Carney complex (CNC) is a familial multiple neoplasia and lentiginosis syndrome with features overlapping those of McCune-Albright syndrome (MAS) and other multiple endocrine neoplasia (MEN) syndromes like MEN type 1 (MEN 1). Pituitary tumors have been described in a number of patients with CNC; all have been growth ho... | 10.1159/000079049 |
36532385 | Knowledge of Musculoskeletal Medicine in Junior Doctors in Australia: Is It Adequate? | The incidence of musculoskeletal disease is increasing in Australia and around the world. However, medical student education does not necessarily reflect current and projected trends in musculoskeletal medicine. The aim of this study was to assess junior doctors' competency in musculoskeletal medicine using the Freedma... | 10.1007/s40670-022-01637-3 |
22451728 | Gene expression profiles in genetically different mice infected with Toxoplasma gondii: ALDH1A2, BEX2, EGR2, CCL3 and PLAU. | Toxoplasma gondii can modulate host cell gene expression; however, determining gene expression levels in intermediate hosts after T. gondii infection is not known much. We selected 5 genes (ALDH1A2, BEX2, CCL3, EGR2 and PLAU) and compared the mRNA expression levels in the spleen, liver, lung and small intestine of gene... | 10.3347/kjp.2012.50.1.7 |
21085746 | Relationship between iron deficiency and anemia in children younger than 4 years. | To evaluate the prevalence of anemia, iron deficiency and iron deficiency anemia in a cohort of children. A cohort study nested in a randomized field trial. Children were recruited at birth at the maternity unit of the only public hospital in the city of São Leopoldo, southern Brazil. This study assessed iron status (h... | 10.2223/JPED.2039 |
22798834 | 3-Methyl-4-[2-(4-nitro-phen-yl)hydrazin-1-yl-idene]-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothio-amide. | The asymmetric unit of the title compound, C(11)H(10)N(6)O(3)S, contains two independent mol-ecules, each of which is stabilized by an intra-molecular N-H⋯O hydrogen bond, forming an S(6) ring motif. In one mol-ecule, the pyrazole ring forms a dihedral angle of 10.93 (14)° with the benzene ring. The corresponding dihed... | 10.1107/S1600536812027134 |
23327091 | [Effects of oral health care for lung cancer patients with surgery--improvement of cough reflex]. | The number of lung cancer patients is increasing. One complication of particular concern after surgery for lung cancer is postoperative pneumonia. The present study examined the various effects of oral care cough reflexes (cough reflex test), oral health conditions (OAG and face scale), and immune function (NK cell act... | |
1992690 | Reduction of cardiovascular disease-related mortality among postmenopausal women who use hormones: evidence from a national cohort. | A national sample of 1944 white menopausal women greater than or equal to 55 years old from the epidemiologic follow-up of participants in the National Health and Nutrition Examination Survey was reviewed to investigate the role of hormone therapy in altering the risk of death from cardiovascular disease. Women in the ... | 10.1016/s0002-9378(11)80006-2 |
22194124 | The traumatic brain injury: diagnosis and management at emergency department by general surgeon. A retrospective critical analysis on the use of the CT head scan. | In recent decades, considerable progress has been made in diagnosis and management of cranial trauma patients. Computed Tomography has resulted in a revolution in head injury diagnosis, making it possible to detect cases suitable for surgical treatment in a rapid, non-invasive manner. We present our experience in treat... | 10.5137/1019-5149.JTN .3749-10.1 |
24013569 | Prescription and adherence to lymphedema self-care modalities among women with breast cancer-related lymphedema. | To profile the prescription for and adherence to breast cancer-related lymphedema (BCRL) self-care modalities among breast cancer (BrCa) survivors with BCRL in a 12-month randomized weightlifting trial. We developed a questionnaire that assessed prescription for and adherence to 10 BCRL self-care modalities that includ... | 10.1007/s00520-013-1962-9 |
13677296 | [Surgical removal of choroidal neovascularization in angioid streaks]. | All the studies so far on surgical removal of choroidal neovascularization (CNV) in angioid streaks(AS) were conducted on a small number of cases. Therefore, a definitive evaluation of the surgical method was not available. The present study aimed to evaluate this surgical modality. We performed surgical removal of fov... | |
9596863 | [Magnesium and calcium concentration of peripheral serum and mononuclear cells in patients with pregnancy induced hypertension]. | To evaluate the magnesium and calcium concentration of peripheral serum and mononuclear in patients with pregnancy induced hypertension (PIH). Twenty-six patients with PIH and 27 healthy women in their late pregnancy were studied. The serum and mononuclear cells magnesium and calcium contents were measured with atomic ... | |
34761293 | C. elegans: out on an evolutionary limb. | The natural environment of the free-living nematode Caenorhabditis elegans is rich in pathogenic microbes. There is now ample evidence to indicate that these pathogens exert a strong selection pressure on C. elegans, and have shaped its genome, physiology, and behaviour. In this short review, we concentrate on how C. e... | 10.1007/s00251-021-01231-8 |
10790346 | Reducing cardiac filling pressure lowers norepinephrine spillover in patients with chronic heart failure. | We studied the cardiac sympathetic response to selective unloading of cardiopulmonary baroreceptors in subjects with normal left ventricular (LV) function and congestive heart failure (CHF). Eight patients with normal LV function (age 57+/-5 years, ejection fraction 58+/-2%) and 8 patients with CHF (age 60+/-2 years; e... | 10.1161/01.cir.101.17.2053 |
36572623 | Functional assessment of DMRT1 variants and their pathogenicity for isolated male infertility. | To study the impact of Doublesex and mab-3-related transcription factor 1 (DMRT1) gene variants on the encoded protein's function and the variants' pathogenic relevance for isolated male infertility caused by azoospermia. This study established a novel luciferase assay for DMRT1 missense variants using 2 different targ... | 10.1016/j.fertnstert.2022.10.032 |
15367617 | Dual role of prostratin in inhibition of infection and reactivation of human immunodeficiency virus from latency in primary blood lymphocytes and lymphoid tissue. | To design strategies to purge latent reservoirs of human immunodeficiency virus type 1 (HIV-1), we investigated mechanisms by which a non-tumor-promoting phorbol ester, prostratin, inhibits infection of CD4(+) T lymphocytes and at the same time reactivates virus from latency. CD4(+) T lymphocytes from primary blood mon... | 10.1128/JVI.78.19.10507-10515.2004 |
22173846 | Does anti-TNF therapy cause any change in platelet activation in ankylosing spondylitis patients? A comparative study. | Recently, it has been reported that ankylosing spondylitis (AS) was characterised by endothelial dysfunction and the development of atherosclerotic complications. In this study, we evaluated platelet and endothelial activation parameters in AS patients. Fiftynine AS patients and 22 healthy controls were included. The c... | 10.1007/s11239-011-0663-9 |
23115222 | The antinociceptive effects of nicotinic receptors α7-positive allosteric modulators in murine acute and tonic pain models. | The α7 nicotinic acetylcholine receptor (nAChR) subtype is abundantly expressed in the central nervous system and in the periphery. Recent evidence suggests that α7 nAChR subtypes, which can be activated by an endogenous cholinergic tone, comprising acetylcholine and the α7 nAChR agonist choline, play an important role... | 10.1124/jpet.112.197871 |
1915309 | Mutagenicity of methylazoxymethanol acetate in the presence of alcohol dehydrogenase, aldehyde dehydrogenase, and rat liver microsomes in Salmonella typhimurium His G46. | Methylazoxymethanol (MAM) is the short-lived toxic and carcinogenic aglycone of cycasin, a natural component of the cycad plant. In the present study, the stable acetate ester of MAM, MAM acetate, was tested in combination with porcine liver esterase and Salmonella typhimurium His G46 to study the comparative mutagenic... | 10.1002/em.2850180302 |
37664250 | Ayurvedic Treatment Protocol for Hereditary Pancreatitis: A Case Report Demonstrating Disease Arrestation. | The case report presented here highlights the use of an Ayurvedic treatment protocol (ATP) in managing hereditary pancreatitis (HP) in a 14-year-old boy. HP is a rare form of pancreatitis caused by specific gene mutations that are inherited within families. It is known to be aggressive and can lead to pancreatic cancer... | 10.7759/cureus.42876 |
2478805 | Mechanisms of downregulation of beta-adrenergic receptors: perspective on the role of beta-adrenergic receptors in congestive heart failure. | The impaired inotropic responsiveness of myocardial tissue to catecholamines in congestive heart failure has been ascribed to downregulation of beta-adrenergic receptors. It has been reported recently that resistance to catecholamines is related to a defect in the guanine nucleotide binding protein that couples the bet... | |
18923037 | The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2. | The role(s) of the novel stargazin-like gamma-subunit proteins remain controversial. We have shown previously that the neuron-specific gamma7 suppresses the expression of certain calcium channels, particularly Ca(V)2.2, and is therefore unlikely to operate as a calcium channel subunit. We now show that the effect of ga... | 10.1523/JNEUROSCI.2709-08.2008 |
10918316 | Comparison of the quantification precision of human short echo time (1)H spectroscopy at 1.5 and 4.0 Tesla. | Precise quantification of human in vivo short echo time (1)H spectra remains problematic at clinical field strengths due to broad peak linewidths and low signal-to-noise ratio (SNR). In this study, multiple STEAM spectra (TE = 20 ms, volume = 8 cm(3)) were acquired in a single individual at 1.5 T and 4 T to compare qua... | 10.1002/1522-2594(200008)44:2<185::aid-mrm4>3.0.co;2-v |
21913340 | Identification of molecular motors in the Woods Hole squid, Loligo pealei: an expressed sequence tag approach. | The squid giant axon and synapse are unique systems for studying neuronal function. While a few nucleotide and amino acid sequences have been obtained from squid, large scale genetic and proteomic information is lacking. We have been particularly interested in motors present in axons and their roles in transport proces... | 10.1002/cm.20531 |
799984 | Nefopam hydrochloride: new analgesic agent. | Two dose-levels of nefopam hydrochloride (i. e. 30 mg and 60 mg) were compared with two dose-levels of aspirin (i. e. 300 mg and 600 mg) and placebo in 125 male patients having pain associated with muscle disorders. Drugs were given as a single dose and pain intensity and side-effects monitored at thirty minutes and th... | 10.1177/030006057600400211 |
22642985 | Bone and mucosal dosimetry in skin radiation therapy: a Monte Carlo study using kilovoltage photon and megavoltage electron beams. | This study examines variations of bone and mucosal doses with variable soft tissue and bone thicknesses, mimicking the oral or nasal cavity in skin radiation therapy. Monte Carlo simulations (EGSnrc-based codes) using the clinical kilovoltage (kVp) photon and megavoltage (MeV) electron beams, and the pencil-beam algori... | 10.1088/0031-9155/57/12/3885 |
18964689 | Assessment of the feasibility of determination of cholesterol and other blood constituents by near-infrared reflectance analysis. | Near-infrared reflectance spectrometry of blood serum can yield values for serum cholesterol that correlate reasonably well (r = 0.96) with those from common reference analytical methods. However, the variability of serum can cause ostensibly validated calibrations to fail on new samples. The determination of blood com... | 10.1016/0039-9140(89)80095-5 |
30824200 | Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration. | The relaxin family peptide receptors have been implicated in numerous physiological processes including energy homeostasis, cardiac function, wound healing, and reproductive function. Two family members, RXFP3 and RXFP4, are class A GPCRs with endogenous peptide ligands (relaxin-3 and insulin-like peptide 5 (INSL5), re... | 10.1016/j.bmcl.2019.02.013 |
35116655 | MiRNA-339 targets and regulates ZNF689 to inhibit the proliferation and invasion of gastric cancer cells. | Gastric cancer (GC) is the most common malignant tumor of the digestive system, and its mortality rate ranks first among malignant tumors. However, the pathogenesis of GC has not yet been fully elucidated. This study found that microRNA (miRNA)-339 is abnormally expressed in GC tissues. However, the role and molecular ... | 10.21037/tcr-21-994 |
33827899 | Prevalence of bla CTX-M Genes in Gram-Negative Bloodstream Isolates across 66 Hospitals in the United States. | Understanding bacterial species at greatest risk for harboring bla CTX-M genes is necessary to guide antibiotic treatment. We identified the species-specific prevalence of bla CTX-M genes in Gram-negative clinical isolates from the United States. Twenty-four microbiology laboratories representing 66 hospitals using the... | 10.1128/JCM.00127-21 |
39396808 | Navigating Dilemmas on Advance Euthanasia Directives of Patients with Advanced Dementia. | This study revisited the complexities faced by physicians in meeting due care criteria for euthanasia in patients with advanced dementia in The Netherlands. Despite increasing cases and legal provisions for advance euthanasia directives (AEDs), physicians encounter challenges with ethical issues, including patient comm... | 10.1016/j.jamda.2024.105300 |
37656873 | Defining a core microbial necrobiome associated with decomposing fungal necromass. | Despite growing interest in fungal necromass decomposition due to its importance in soil carbon retention, whether a consistent group of microorganisms is associated with decomposing necromass remains unresolved. Here, we synthesize knowledge on the composition of the bacterial and fungal communities present on decompo... | 10.1093/femsec/fiad098 |
10703751 | A practical method for non-surgically inserting intra-arterial catheters in European wild boars (Sus scrofa). | In endocrinological studies, the usual methods for taking blood samples are impractical because of the need for frequent sampling, and catheterization is required. The catheterization methods described for domestic pigs are not suitable for use with European wild boars (Sus scrofa) under field conditions. We describe a... | 10.1023/a:1006321204331 |
9344412 | Preparation of enantiomerically pure L-7-azatryptophan by an enzymatic method and its application to the development of a fluorimetric activity assay for tryptophanyl-tRNA synthetase. | The reaction of D,L-7-azatryptophan (D,L-7AW) with tryptophanyl-tRNA synthetase (TrpRS), adenosine triphosphate (ATP), and Mg2+ in the presence of inorganic pyrophosphatase results in the formation of a highly fluorescent l-7AW-adenylate complex. Detection of this complex is based on its enhanced fluorescence at 315 nm... | 10.1006/abio.1997.2286 |
25074561 | Pilot early intervention antenatal group program for pregnant women with anxiety and depression. | This study aims to examine the acceptability and effectiveness of an antenatal group intervention designed to reduce the severity of depression and anxiety symptoms and improve maternal attachment in pregnant women with current or emerging depression and anxiety. Women who participated in the program completed pre- and... | 10.1007/s00737-014-0447-2 |
32246954 | Analysis of differences in eating alone attitude of Koreans by dietary habits and age. | This study compares differences in eating alone attitude according to dietary habits and age in Seoul and Gyeonggi-do region in South Korea. Out of total 411 participants, 207(50.4%) were males and 204(49.6%) were females. 30 types of eating alone attitude were identified to perform a factor analysis; further these 30 ... | 10.1016/j.appet.2020.104695 |
1380237 | [Catalytic activity of immune complexes of peroxidase and its conjugates with cortisol in Aerosol OT reverse micelles]. | Conjugates containing 1, 6 or 11 cortisol molecules per peroxidase molecule were obtained by the reaction of the N-hydroxysuccinimide ester of cortisol 3-O-carboxymethyloxime (COR) with horse-radish peroxidase (HRP). Activities of the peroxidase conjugates and their immunocomplexes with antibodies against cortisol in t... | |
25779638 | A Plant-Derived Multi-HIV Antigen Induces Broad Immune Responses in Orally Immunized Mice. | Multi-HIV, a multiepitopic protein derived from both gp120 and gp41 envelope proteins of the human immunodeficiency virus (HIV), has been proposed as a vaccine prototype capable of inducing broad immune responses, as it carries various B and T cell epitopes from several HIV strains. In this study, the immunogenic prope... | 10.1007/s12033-015-9856-3 |
721673 | Surgical correction of deviated nasal septum and premaxilla in a colt. | A 6-month-old Appaloosa colt had a deviation of the premaxilla and nasal septum as well as a dorsal hump of the nasal bone and maxillomandibular malocclusion. Two surgical procedures were performed 12 weeks apart to correct these anomalies. An intraoral approach and autogenous rib graft were used to correct the maloccl... | |
20519928 | [A case of testicular tumor with inferior vena cava thrombus]. | A 31-year-old man presented with edema in left lower leg and dyspnea. Computed tomographic scanning detected a right testicular tumor, multiple lung nodules, and inferior vena cava (IVC) thrombus. After insertion of an IVC filter, high inguinal orchiectomy was performed after the first combination chemotherapy. Patholo... | |
28993628 | Oxidized g-C 3 N 4 /polyaniline nanofiber composite for the selective removal of hexavalent chromium. | Nanomaterials with selective adsorption properties are in demand for environmental applications. Herein, acid etching and oxidative decomposition of melon units of graphitic carbon nitride (g-C 3 N 4 ) was performed to obtain the oxidized graphitic carbon nitride (Ox-g-C 3 N 4 ) nanosheets. Ox- g-C 3 N 4 nanosheets wer... | 10.1038/s41598-017-12850-1 |
574433 | Neuraminidase activity in the mucolipidoses (types I, II and III) and the cherry-red spot myoclonus syndrome. | Two neuraminidase (EC 3.2.1.18) comonents, A and B, were distinguished in cultured skin fibroblasts on the basis of thermolability at 37 degrees C. The more labile component (A) t1/2 = 4.7--5.3 min at 37 degrees C, comprises 66--90% of total neuraminidase activity when determined using sodium (4-methylumbelliferyl-alph... | 10.1016/0009-8981(79)90031-7 |
3599037 | Reaction of lecturers to analysis results of student ratings of their lecture skills. | Lecturers in a medical biochemistry course were evaluated by medical students with respect to overall impression and seven specific characteristics expected to predict overall impression. Each lecturer's ratings were subjected to stepwise multiple regression analysis to identify the characteristics that best accounted ... | 10.1097/00001888-198706000-00006 |
14523385 | Roles of the NKG2D immunoreceptor and its ligands. | According to present concepts, innate immunity is regulated by receptors that determine danger levels by responding to molecules that are associated with infection or cellular distress. NKG2D is, perhaps, the best characterized receptor that is associated with responses to cellular distress, defined as transformation, ... | 10.1038/nri1199 |
2250993 | The pronator compression test revisited. A forgotten physical sign. | Pronator compression testing is a valuable clinical feature of median nerve entrapment diagnosis. Of 10 patients with this disorder, all developed paresthesias preoperatively in the hand after 30 seconds or less of manual compression of the median nerve at or near the pronator muscle. Eight patients had a positive Tine... | |
39620950 | Biomimetic Cell Membrane Layers for the Detection of Insulin and Glucagon. | The growing need for reliable and rapid insulin testing to enhance glycemic management has spurred intensive exploration of new insulin-binding bioreceptors and innovative biosensing platforms for detecting this hormone, along with glucagon, in biological samples. Here, by leveraging the native protein receptors on the... | 10.1021/acs.analchem.4c05347 |
29201399 | Renewing focus on family planning service quality globally. | Reducing the global unmet need for contraception is currently a priority for many governments, multi-lateral initiatives, non-governmental organizations, and donors. Evidence strongly suggests that the provision of quality family planning services can increase uptake, prevalence, and continuation of contraception. Whil... | 10.1186/s40834-016-0021-6 |
38719175 | Downregulation of HHATL promotes cardiac hypertrophy via activation of SHH/DRP1. | HHATL, previously implicated in cardiac hypertrophy in the zebrafish model, has emerged as a prioritized HCM risk gene. We identified six rare mutations in HHATL, present in 6.94 % of nonsarcomeric HCM patients (5/72). Moreover, a decrease of HHATL in the heart tissue from HCM patients and cardiac hypertrophy mouse mod... | 10.1016/j.yexcr.2024.114072 |
826923 | A mass fragmentographic method for the determination of chlorpromazine and two of its active metabolites in human plasma and CSF. | A mass fragmentographic method for the quantitation of chlorpromazine (CPZ), mono-demethyl-chlorpromazine (nor1-CPZ), and 7-hydroxy-chlorpromazine (7-OH-CPZ) in plasma, cerebrospinal fluid, and tissues has been developed. The deuterated analogues of the compounds are used as internal standards. The high specificity was... | 10.1007/BF00423250 |
30594528 | Adrenergic and adenosinergic regulation of the cardiovascular system in an Antarctic icefish: Insight into central and peripheral determinants of cardiac output. | Icefishes characteristically lack the oxygen-binding protein haemoglobin and therefore are especially reliant on cardiovascular regulation to augment oxygen transport when oxygen demand increases, such as during activity and warming. Using both in vivo and in vitro experiments, we evaluated the roles for adrenaline and... | 10.1016/j.cbpa.2018.12.012 |
24114443 | Metabolic alteration in tumorigenesis. | Altered metabolism in cancer was first discovered by Otto Warburg early last century. Although the Warburg Effect has been widely used in tumor detection, relatively little progress had been made in mechanistic understanding of cancer metabolism in the subsequent eight decades. Genetic studies have recently identified ... | 10.1007/s11427-013-4549-2 |
12807407 | Voluntary head movement and allocentric perception of space. | Although visual input is egocentric, at least some visual perceptions and representations are allocentric, that is, independent of the observer's vantage point or motion. Three experiments investigated the visual perception of three-dimensional object motion during voluntary and involuntary motion in human subjects. Th... | 10.1111/1467-9280.14491 |
16249279 | Reactive oxygen species-induced oxidative stress in the development of insulin resistance and hyperandrogenism in polycystic ovary syndrome. | Insulin resistance and chronic low level inflammation are often present in women with polycystic ovary syndrome (PCOS). The purpose of this study was to determine the effects of hyperglycemia on reactive oxygen species (ROS) generation from mononuclear cells (MNCs) in PCOS. This was a prospective controlled study. The ... | 10.1210/jc.2005-1696 |
4353380 | The heterogeneous distribution of acid hydrolases within a homogeneous population of cultured mammalian cells. | 1. Chinese-hamster ovary fibroblasts were cultured to provide a homogeneous cell population. Homogenates obtained from these cells were fractionated by centrifugation techniques and the resulting fractions were analysed for protein and for enzymes representative of certain subcellular particles. 2. Unlike those in rat ... | 10.1042/bj1320493 |
24443848 | Building the bacterial orisome: high-affinity DnaA recognition plays a role in setting the conformation of oriC DNA. | During assembly of the E. coli pre-replicative complex (pre-RC), initiator DnaA oligomers are nucleated from three widely separated high-affinity DnaA recognition sites in oriC. Oligomer assembly is then guided by low-affinity DnaA recognition sites, but is also regulated by a switch-like conformational change in oriC ... | 10.1111/mmi.12525 |
33809547 | The Feasibility Study of Hypofractionated Radiotherapy with Regional Hyperthermia in Soft Tissue Sarcomas. | Management of marginally resectable or unresectable soft tissue sarcomas (STS) in patients who are not candidates for neoadjuvant chemotherapy due to chemoresistant pathology or contraindications remains a challenge. Therefore, in these indications, we aimed to investigate a feasibility of 10x 3.25 Gy radiotherapy comb... | 10.3390/cancers13061332 |
12127580 | Activity and properties of alpha-L-fucosidase are dependent on the state of enterocytic differentiation of HT-29 colon cancer cells. | Previously we have demonstrated an impairment in the activity of alpha-L-fucosidase in colon tumours. In order to establish an in vitro model to study this enzyme in colon cancer, we have determined the activity and properties of the enzyme during the differentiation of HT-29 colon cancer cells. Cultures were committed... | 10.1016/s1357-2725(02)00067-5 |
35037670 | Correction: Selective light driven reduction of CO 2 to HCOOH in water using a {MoV 9 } n ( n = 1332-3600) based soft-oxometalate (SOM). | Correction for 'Selective light driven reduction of CO 2 to HCOOH in water using a {MoV 9 } n ( n = 1332-3600) based soft-oxometalate (SOM)' by Soumitra Barman et al., Chem. Commun., 2018, 54, 2369-2372, DOI: 10.1039/C7CC09520A. | 10.1039/d2cc90018a |
9210926 | Correlation of bovine viral diarrhoea virus induced cytopathic effects with expression of a biotype-specific marker. | The purpose of this study was the identification antigenic differences between cytopathic (cp) and noncytopathic (ncp) bovine viral diarrhoea viruses (BVDV). Cells infected with 19 strains of each viral biotype were analyzed for reactivity with the monoclonal antibody (mab) BVD/C38. Reactivity was examined using an enz... | 10.1007/978-3-7091-9153-8_7 |
11981653 | Occupational respiratory hypersensitivity in dental personnel. | The aim was to study the causes of respiratory hypersensitivity in dental personnel based on the statistics of the Finnish Register of Occupational Diseases (FROD; 1975-1998) and the patient material of the Finnish Institute of Occupational Health (FIOH; 1990-1998). Details about the cases of respiratory hypersensitivi... | 10.1007/s00420-001-0302-4 |
36968223 | A Phase I Trial of VEGF-A Inhibition Combined with PD-L1 Blockade for Recurrent Glioblastoma. | The treatment of glioblastoma (GBM) poses challenges. The use of immune checkpoint inhibition (ICI) has been disappointing as GBM is characterized by low mutational burden and low T-cell infiltration. The combination of ICI with other treatment modalities may improve efficacy. Patients with recurrent GBM were treated w... | 10.1158/2767-9764.CRC-22-0420 |
21519530 | The clinical research center for depression study: baseline characteristics of a korean long-term hospital-based observational collaborative prospective cohort study. | The Clinical Research Center for Depression (CRESCEND) study is a 9-year observational collaborative prospective cohort study for the clinical outcomes in participants with depressive disorders in Korea. In this study, we examined the baseline characteristics of the depressive participants as the hospital-based cohort.... | 10.4306/pi.2011.8.1.1 |
37017312 | WhereWulff: A Semiautonomous Workflow for Systematic Catalyst Surface Reactivity under Reaction Conditions. | This paper introduces WhereWulff, a semiautonomous workflow for modeling the reactivity of catalyst surfaces. The workflow begins with a bulk optimization task that takes an initial bulk structure and returns the optimized bulk geometry and magnetic state, including stability under reaction conditions. The stable bulk ... | 10.1021/acs.jcim.3c00142 |
6280111 | Inhibition of the electrically induced release of [3H]dopamine by serotonin from superfused rat striatal slices. | The effect of serotonin (5-hydroxytryptamine) on the electrically induced release of [3H]dopamine from superfused slices of the rat striatum has been studied. It was observed that serotonin produced a concentration dependent decrease in the field stimulation-induced release of [3H]dopamine with the threshold concentrat... | 10.1016/0304-3940(82)90153-7 |
24130374 | Clinical pharmacology training in India: Status and need. | Clinical pharmacologists undertake many tasks, and this makes defining a curriculum challenging. This is especially so under the changing circumstances in developing countries, where clinical pharmacology has an expanding role. The clinical pharmacologist may be responsible for conducting ethical clinical trials, suppo... | 10.4103/0253-7613.117718 |
9602026 | Genomic structure of Unp, a murine gene encoding a ubiquitin-specific protease. | The murine Unp gene encodes a ubiquitin-specific protease, a member of a family of enzymes that includes the product of the human tre-2 oncogene. The Unp gene has previously been mapped to chromosome 9. We have cloned in bacteriophage a 50 kilobase region of chromosome 9 containing the Unp gene, and have determined the... | 10.1016/s0167-4781(98)00035-9 |
24284386 | Differential expression of vascular smooth muscle-modulating microRNAs in human peripheral blood mononuclear cells: novel targets in essential hypertension. | Vascular smooth muscle cell (VSMC) phenotypic plasticity has a critical role in the pathophysiology of arterial remodeling in essential hypertension. MicroRNAs are emerging as potential biomarkers and therapeutic targets in cardiovascular disease. We assessed the expression levels of the microRNAs miR-143, miR-145, miR... | 10.1038/jhh.2013.117 |
31004298 | The relation between stressful life events and breast cancer: a systematic review and meta-analysis of cohort studies. | Breast cancer is the most common cancer among women with high rate of mortality. This systematic review and meta-analysis was conducted to investigate the relation between stressful life events and breast cancer. We searched PubMed, Scopus, ScienceDirect, and Google scholar databases from their inception until June 201... | 10.1007/s10549-019-05231-x |
33571748 | Supplementing pregnant Merino ewes with caffeine to improve neonatal lamb thermoregulation and viability. | Percentages of lamb mortalities prior to weaning are a significant and persistent problem for the Australian sheep industry. Maternal caffeine supplementation reduced stillbirths and improved viability in piglets; however, the efficacy of caffeine in enhancing viability and lamb survival is equivocal. The aim of this s... | 10.1016/j.anireprosci.2021.106715 |
26612762 | The classification of hospitalized patients with hyperglycemia and its implication on outcome: results from a prospective observational study in Internal Medicine. | The relevance of classifying hyperglycemic hospitalized subjects (HS) as known diabetes (D), newly discovered diabetes (ND), and stress hyperglycemia (SH) is unclear. The aim of this study was to determine the prevalence, in-hospital mortality, and length of stay (LOS) of three different phenotypes of HS. Fasting gluco... | 10.1007/s11739-015-1358-6 |
11192954 | Home-based exercise is capable of preserving hospital-based improvements in severe chronic obstructive pulmonary disease. | We examined the feasibility of home-based walking training to maintain the benefits of a short-term exercise training in patients with severe chronic obstructive pulmonary disease (COPD). After initial recovery from an exacerbation, 46 patients were randomized into a training and a control group, and 30 patients comple... | 10.1053/rmed.2000.0949 |
8545529 | Differential cholinergic regulation in Alzheimer's patients compared to controls following chronic blockade with scopolamine: a SPECT study. | The effects of low-dose chronic scopolamine on measures of cerebral perfusion and muscarinic receptors were tested in eight Alzheimer's disease (AD) subjects and eight elderly controls. Single photon emission computed tomography (SPECT) scans using technetium-labelled hexamethypropylene amine oxide (99mTc-HMPAO) to mea... | 10.1007/BF02245634 |
2434764 | Clinical studies with a vascular vasopressin antagonist. | The effect of circulating arginine vasopressin (AVP) on blood pressure, heart rate, and skin blood flow was assessed in normotensive subjects, mild hypertensive patients, and patients with congestive heart failure, utilizing the specific antagonist of AVP at the vascular receptor level, d(CH2)5Tyr(Me)AVP (5 micrograms/... | 10.1097/00005344-198600087-00022 |
39699626 | An updated examination of gender differences in sexual harassment perception: A meta-analysis and a survey study. | Twenty years ago, Rotundo et al. (2001) meta-analyzed the gender differences in sexual harassment (SH) perception. They found an overall d of 0.30: Women are more likely than men to label certain behaviors as SH. Much has changed since then, including the increased social awareness and the prevalence of SH training. Gi... | 10.1037/ocp0000391 |
34359490 | Eco-Efficiency of the Fisheries Value Chains in the Gambia and Mali. | The Gambian and Malian fisheries and fish processing value chains are predominantly artisanal and represent a key source of protein and livelihoods, yet their eco-efficiency has not been studied to date. A Life Cycle Assessment was used to estimate the associated environmental impacts of those value chains and provide ... | 10.3390/foods10071620 |
39074816 | Efficacy of verdinexor for the treatment of naïve canine epitheliotropic cutaneous T-cell lymphoma: An open-label pilot study. | Verdinexor (Laverdia-CA1; Dechra Veterinary Products), a selective inhibitor of nuclear export, has been utilised for treatment of non-Hodgkin T-cell lymphoma in dogs. However, the efficacy of verdinexor has not been evaluated for cutaneous epitheliotropic T-cell lymphoma (CETL). To evaluate the efficacy of verdinexor ... | 10.1111/vde.13280 |
12465113 | Band artifacts due to bulk motion. | Band artifacts due to bulk motion were investigated in images acquired with fast gradient echo sequences. A simple analytical calculation shows that the width of the artifacts has a square-root dependence on the velocity of the imaged object, the time taken to acquire each line of k-space and the field of view in the p... | 10.1002/mrm.10314 |
8670406 | The Argentine Precordillera: A Traveler from the Ouachita Embayment of North American Laurentia | The Argentine Precordillera is a continental fragment rifted from the Ouachita embayment of the southern margin of Laurentia (North America) during Cambrian time [about 515 million years ago (Ma)] and accreted to the western margin of Gondwana (South America) during Ordovician time (about 455 Ma). Similarities of Cambr... | 10.1126/science.273.5276.752 |
21787222 | The role of cytokines in the pathogenesis and treatment of systemic lupus erythematosus. | Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is characterized by a defect in immune tolerance and exacerbated by both the innate and adaptive arms of the immune response. SLE-associated immune hyperactivity can be detected systemically as elevations in levels of cytokines along with their upr... | 10.1089/jir.2011.0047 |
25877041 | Water response to intense electric fields: A molecular dynamics study. | This paper investigated polarization properties of water molecules in close proximity to an ionic charge in the presence of external electric fields by using an approach based on simulations at the atomic level. We chose sodium and chloride ions in water as examples of dilute ionic solutions and used molecular dynamics... | 10.1002/bem.21916 |
26073997 | Effects of GLC7 and REG1 deletion on maltose metabolism and leavening ability of baker's yeast in lean dough. | Maltose metabolism and leavening ability of baker's yeast (Saccharomyces cerevisiae) in lean dough is negatively influenced by glucose repression. To improve maltose metabolism and leavening ability, it is necessary to alleviate glucose repression. In this study, we focus on the effects of regulators (GLC7 encoding the... | 10.1016/j.jbiotec.2015.06.386 |
12837710 | Results of repeat sigmoidoscopy 3 years after a negative examination. | The necessary frequency of endoscopic colorectal cancer screening after a negative examination is uncertain. To examine the yield of adenomas and cancer in the distal colon found by repeat flexible sigmoidoscopy (FSG) 3 years after a negative examination. Participants were drawn from the Prostate, Lung, Colorectal, and... | 10.1001/jama.290.16.2123-b |
17906199 | Pharmacogenomic strategies provide a rational approach to the treatment of cisplatin-resistant patients with advanced cancer. | Standard treatment for advanced non-small-cell lung cancer (NSCLC) includes the use of a platinum-based chemotherapy regimen. However, response rates are highly variable. Newer agents, such as pemetrexed, have shown significant activity as second-line therapy and are currently being evaluated in the front-line setting.... | 10.1200/JCO.2007.11.0593 |
29382134 | Phage-Bacterial Dynamics with Spatial Structure: Self Organization around Phage Sinks Can Promote Increased Cell Densities. | Bacteria growing on surfaces appear to be profoundly more resistant to control by lytic bacteriophages than do the same cells grown in liquid. Here, we use simulation models to investigate whether spatial structure per se can account for this increased cell density in the presence of phages. A measure is derived for co... | 10.3390/antibiotics7010008 |
28155636 | Spectra library assisted de novo peptide sequencing for HCD and ETD spectra pairs. | De novo peptide sequencing via tandem mass spectrometry (MS/MS) has been developed rapidly in recent years. With the use of spectra pairs from the same peptide under different fragmentation modes, performance of de novo sequencing is greatly improved. Currently, with large amount of spectra sequenced everyday, spectra ... | 10.1186/s12859-016-1330-0 |
23099740 | [Men, health and public policies: gender equality in question]. | The scope of this article is to pose questions on the theme of Men, Health and Public Policies to render debate on the subject viable, based on theoretical and empirical references related to these issues. Initially, some historical landmarks on the theme are presented to provide guidelines for debate. An overview of t... | 10.1590/s1413-81232012001000002 |
25525422 | Synthesis, Spectroscopic, Molecular Structure, and Antibacterial Studies of Dibutyltin(IV) Schiff Base Complexes Derived from Phenylalanine, Isoleucine, and Glycine. | New series of organotin(IV) complexes and Schiff bases derived from amino acids have been designed and synthesized from condensation of 1H-indole-2,3-dione, 5-chloro-1H-indole-2,3-dione, and α-amino acids (phenylalanine, isoleucine, and glycine). All compounds are characterized by elemental analyses, molar conductance ... | 10.1155/2014/716578 |
25720528 | Allergenicity of pasteurized whole raw Hen's egg compared with fresh whole raw Hen's egg. | Oral food challenges for diagnosis and management of egg allergy using fresh egg are common; however, to limit the risk of foodborne infection, many allergy units use pasteurized raw egg. Pasteurization and drying processes have the potential to affect the structure of egg proteins in egg powder and thus the allergenic... | 10.1111/pai.12365 |
15788805 | Monitoring health inequalities through general practice: the Second Dutch National Survey of General Practice. | For the second time a plan to monitor public health and health inequalities in the Netherlands through general practice was put into action: the Second National Survey of General Practice (DNSGP-2, 2001). The first aim of this paper is to describe the general design of DNSGP-2. Secondly, to describe self assessed healt... | 10.1093/eurpub/cki116 |
24476142 | The way we teach: basic clinical skills. | At the University of Adelaide Medical School, students are given additional intensive training in basic clinical skills during a six-week period in the fifth year. The course includes history-taking, physical examination, decision making and problem solving. Teaching activities are based predominantly on a preceptor sy... | 10.3109/01421598209034740 |
35946330 | Risk factors associated with cardiovascular mortality among gastric cancer patients: a population-based analysis. | Cancer patients were found at a high risk of death from cardiovascular disease. This study aims to assess cardiovascular mortality risk and identify the potential risk factors associated with cardiovascular mortality among gastric cancer patients. Gastric cancer patients were collected from the Surveillance Epidemiolog... | 10.1093/jjco/hyac132 |
15871253 | Spatial variability and uncertainty in ecological risk assessment: a case study on the potential risk of cadmium for the little owl in a Dutch river flood plain. | This paper outlines a procedure that quantifies the impact of different sources of spatial variability and uncertainty on ecological risk estimates. The procedure is illustrated in a case study that estimates the risks of cadmium for a little owl (Athene noctua vidalli) living in a Dutch river flood plain along the riv... | 10.1021/es049814w |
9221459 | [The role of the stent in non-coronary cardiopathies]. | The stent has demonstrated to be a useful device in the prevention of postangioplasty coronary restenosis and it is expected to have a favourable effect as an alternative or complementary treatment of stenotic lesions in arteries or veins associated with congenital defects. The aim of this study is to analyze our exper... | |
12142917 | Fusion Expression, Immunogenicity and Applications of C-terminally Truncated HCV Core Proteins. | Clones expressing full-length(aa 1-191) or C-terminally truncated forms (aa 1-69 and aa 1-40) of hepatitis C virus core(HCc) protein fused to the C-terminal of glutathione S-transferase(GST) were constructed and their expressions in different strains of Escherichia coli were compared. The expressed proteins were solubl... | |
30653714 | Development and differentiation of the reproductive system of Tropidurus catalanensis (Squamata: Tropiduridae). | Development and differentiation of the reproductive system in lizards begin in the embryonic period, although the stage and time of their occurrence vary according to populations and species. In this study, the events of the development and differentiation of the reproductive system of males and females of Tropidurus c... | 10.1002/jmor.20940 |
721040 | [Pulmonary hypertension and cor pulmonale complicating ventricular vascular shunting for hydrocephalus (author's transl)]. | Obstructive pulmonary vascular disease and pulmonary hypertension are facts daily encountered by pediatric cardiologists. However longterm thromboembolism, pulmonary vascular obstruction and cor pulmonale are rare conditions in children. The case report of a four years old child treated by a Pudenz ventriculo venous sh... | |
16451762 | Comparison of muscle activity associated with structural differences in dental hygiene mirrors. | Ergonomic studies suggest that the commonly used pinch grasp, held in a static position, is a contributing factor for dental Hygienists' development of work-related musculoskeletal disorders (WMSDs) such as carpal tunnel syndrome (CTS), Trigger Thumb, de Quervain's stenosing tenosynovitis, and carpometacarpal (CMC) ost... | |
14591438 | Preliminary examination of cognitive reserve theory in closed head injury. | This investigation was designed to provide preliminary support for cognitive reserve theory in closed head injury (CHI), and demonstrate the effectiveness of using the Oklahoma premorbid intelligence estimate (OPIE) in research and clinical activities. Out of a possible 124 consecutive referrals, 26 patients (N=26) who... | |
27489576 | Fundamental awareness: A framework for integrating science, philosophy and metaphysics. | The ontologic framework of Fundamental Awareness proposed here assumes that non-dual Awareness is foundational to the universe, not arising from the interactions or structures of higher level phenomena. The framework allows comparison and integration of views from the three investigative domains concerned with understa... | 10.1080/19420889.2016.1155010 |
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