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Silibinin: An old drug for hematological disorders
MSTS 2018 - Femur Mets and MM
Introduction: Silibinin (silybin), a non-toxic natural polyphenolic flavonoid, is the principal and the most biologically active component of silymarin. It is efficient in the treatment of acute and chronic liver disorders caused by toxins, drug, alcohol, hepatitis, and gall bladder disorders. Further, in our previous ...
82,183
0
Fracture of the greater trochanter after hip replacement
Management of Hip Fractures in the Elderly
Fracture of the femur is one of the common complications of hip replacement surgery. Five percent of femur fractures involve just the greater trochanter. This series consisted of 21 women and nine men with fractures of just the greater trochanter after total or partial hip replacement. The fracture was displaced 2.5 cm...
8,311
0
Acromioclavicular joint reconstruction with the LARS ligament in professional versus non-professional athletes
DoD SSI (Surgical Site Infections)
PURPOSE: To compare outcomes of acromioclavicular (AC) joint reconstruction with ligament augmentation and reconstruction system (LARS) ligament in professional and non-professional athletes at 2-year minimum follow-up. METHODS: Forty-three patients (men; mean age 30, range 19-54 years) with Rockwood type III to V chro...
150,362
0
En bloc Excision and Matched Metatarsal Transfer for Expansive Benign Osteolytic Lesions of the Metacarpal
DoD SSI (Surgical Site Infections)
Purpose Benign aggressive expansile osteolytic lesions such as giant cell tumors and aneurysmal bone cysts involving the metacarpal head pose problems in management. Unacceptably high rates of recurrence are reported after curettage and bone grafting. An en bloc excision of such tumors ideally requires osteoarticular r...
148,530
0
Effect of preoperative application of buprenorphine transdermal patch on analgesic requirement in postoperative period in hip and knee replacement surgeries
OAK 3 - Non-arthroplasty tx of OAK
Background and Aims: Although no pain control following hip and knee replacement surgeries has attained gold standard, it is clear that patients should have optimum pain control after total knee arthroplasty and total hip arthroplasty for enhanced satisfaction and function. We conducted this study to evaluate the effec...
113,889
1
The clinical and radiographic course of early knee and hip osteoarthritis over 10 years in CHECK (Cohort Hip and Cohort Knee)
OAK 3 - Non-arthroplasty tx of OAK
Objective: To describe the radiographic and symptomatic course in subjects with hip or knee complaints suspected of early osteoarthritis (OA). Design: CHECK (Cohort Hip and Cohort Knee) is a multicenter, prospective observational cohort study of 1,002 subjects with first complaints in knee(s) and/or hip(s) (age 56 ± 5...
114,202
0
Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
Objective: Conventional treatment of osteoarthritis (OA) with non�steroidal anti�inflammatory drugs is associated with serious gastrointestinal side effects and in view of the recent withdrawal of some cyclo�oxygenase�2 inhibitors, identifying safer alternative treatment options is needed. The objective of this...
112,880
1
Sports-related overuse injuries in children
Osteochondritis Dissecans 2020 Review
Increased intensity of sports activities combined with a decrease in daily physical activity is making overuse injuries in children more common. These injuries are located mainly in the epiphyseal cartilage. The broad term for these injuries is osteochondrosis, rather than osteochondritis, which more specifically refer...
140,416
1
Supracondylar humerus fractures in children treated with closed reduction and percutaneous pinning
Pediatric Supracondylar Humerus Fracture 2020 Review
Supracondylar fractures of the humerus in children are important for frequency and type of associated serious complications. The management of this kind of fractures is still controversial (Skaggs et al. in J Bone Joint Surg Am 86:702-707, 2004; Kalllio et al. in J Pediatr Orthop 12:11-15, 1992). We are going to presen...
143,347
0
RESEARCH: A prospective study of a modified pin-in-plaster technique for treatment of fractures of the distal radius
Distal Radius Fractures
Objectives: There are various pin-in-plaster methods for treating fractures of the distal radius. The purpose of this study is to introduce a modified technique of 'pin in plaster'. Methods: Fifty-four patients with fractures of the distal radius were followed for one year post-operatively. Patients were excluded if th...
122,070
0
Biomechanical study of upper-limb exoskeleton for resistance training with three-dimensional motion analysis system
Pediatric Supracondylar Humerus Fracture 2020 Review
The world's population is aging rapidly, particularly in developed countries. The trend toward prolonged life expectancy will increase the elderly population and thereby lead to an increase in occurrences of age-related health problems such as chronic disease. Healthcare services and home-based rehabilitation are in hi...
141,134
0
Shoulder prosthesis in the complex fractures or fractures with dislocation of humeral head: Comparison between endoprosthesis and reverse prosthesis
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Introduction Authors apply shoulder's prosthesis in split 4 fragments fractures of humeral proximal extreme, dislocation fractures of the humeral head, compression fractures involving more than 40 % of the articular surface. Materials and methods We analysed shoulder surgery cases of Dolo's Orthopaedic Unit from Januar...
24,471
0
Shoulder resurfacing in osteoarthritis: Surgical technique and mid-term results
Surgical Management of Osteoarthritis of the Knee CPG
Introduction Shoulder arthroplasty remains the treatment of choice for gleno-humeral osteoarthritis. The modularity of the modern prosthetic systems allow us to choose the implant best suited to the case to be treated. In this study we assessed the mid-term outcomes after shoulder resurfacing in osteoarthritis. Materia...
26,571
0
Acute Management of Traumatic Knee Dislocations for the Generalist
DOD - Acute Comp Syndrome CPG
Acute knee dislocations are an uncommon injury that can result in profound consequences if not recognized and managed appropriately on presentation. Patients presenting with knee pain in the setting of high- or low-energy trauma may have sustained a knee dislocation that spontaneously reduced. Prompt reduction of the d...
64,581
0
Arthritis increases the risk for fractures--results from the Women's Health Initiative
Management of Hip Fractures in the Elderly
OBJECTIVE: To examine the relationship between arthritis and fracture. METHODS: Women were classified into 3 self-reported groups at baseline: no arthritis (n = 83,295), osteoarthritis (OA; n = 63,402), and rheumatoid arthritis (RA; n = 960). Incident fractures were self-reported throughout followup. Age-adjusted fract...
11,493
0
A small new idea for the training of plastic surgery residents
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Today, learning the craft of surgery is threatened by several factors, including the scarce availability of cadaver and animal models. METHODS: We propose the use of human limbs and tissues removed during commonly performed surgical procedures (e.g., lower limb amputations and abdominoplasties) as training ...
126,062
0
Expression and predictive value of lymph-specific markers in urothelial carcinoma of the bladder
MSTS 2018 - Femur Mets and MM
OBJECTIVE: To evaluate the expression of multiple lymph-specific markers and to test its association with histopathological characteristics and clinical outcomes in patients with urothelial carcinoma of the bladder (UCB) treated by radical cystectomy (RC). PATIENTS AND METHODS: Vascular endothelial growth factor-C and ...
81,843
1
Outcome comparison in traumatic lower-extremity reconstruction by using various composite vascularized bone transplantation
DoD SSI (Surgical Site Infections)
Lower-extremity injury may present as a composite soft-tissue and bone defect, resulting directly from trauma or subsequent debridements. These composite defects often require vascularized osteocutaneous flaps for an effective, staged reconstruction. Among various donor sites, the vascularized fibular flap is generally...
151,943
0
Hoffa's fat pad resection in total knee arthroplasty
Surgical Management of Osteoarthritis of the Knee CPG
The authors have studied the consequences of resection of Hoffa's fat pad during total knee arthroplasty (TKA). Sixty eight patients undergoing primary TKA were randomised to have Hoffa's fat pad either resected or preserved. Biopsy specimens of Hoffa's fat pad were taken for pathological study in all patients. Radiolo...
31,147
0
Perioperative contamination in primary total hip arthroplasty
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
All surgical procedures have the risk of microbial contamination. However, procedures in which prosthetic materials are involved have a high risk for future infectious problems because of the protection offered by the biofilm mode of growth. Studies of perioperative contamination have been done on involved surgical ins...
21,371
1
How to Choose Platelet-Rich Plasma or Hyaluronic Acid for the Treatment of Knee Osteoarthritis in Overweight or Obese Patients: A Meta-Analysis
OAK 3 - Non-arthroplasty tx of OAK
Objective. The purpose of this meta-analysis was to determine whether platelet-rich plasma (PRP) was better than hyaluronic acid (HA) for the treatment of knee osteoarthritis (OA) in overweight or obese patients. Design. Two reviewers independently used the keywords combined with free words to search English-based elec...
115,218
0
Oxford medial unicompartmental knee arthroplasty in patients younger and older than 60 years of age
Surgical Management of Osteoarthritis of the Knee CPG
We present a comparison of the results of the Oxford unicompartmental knee arthroplasty in patients younger and older than 60 years of age. The ten-year all-cause survival of the < 60 years of age group (52) was 91% (95% confidence interval (CI) 12), while in the > or = 60 years of age group (512), the figure was 96% (...
30,557
1
Microbiological and functional outcomes after open extremity fractures sustained overseas: The experience of a UK level I trauma centre
DoD SSI (Surgical Site Infections)
Background: Open extremity fractures carry a high risk of limb loss and poor functional outcomes. Transfer of extremity trauma patients from developing countries and areas of conflict adds further layers of complexity due to challenges in the delivery of adequate care. The combination of extensive injuries, transfer de...
152,072
0
Different competing risks models applied to data from the Australian Orthopaedic Association National Joint Replacement Registry
Management of Hip Fractures in the Elderly
PURPOSE: Here we describe some available statistical models and illustrate their use for analysis of arthroplasty registry data in the presence of the competing risk of death, when the influence of covariates on the revision rate may be different to the influence on the probability (that is, risk) of the occurrence of ...
3,643
0
Treatment of simple elbow dislocation using an immediate motion protocol
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
The results of treatment after closed reduction of elbow dislocation vary. Twenty consecutive patients with closed posterior elbow dislocations were treated prospectively on a rapid motion, nonimmobilized functional regimen. This treatment protocol emphasizes immediate active range of motion under close supervision. No...
23,862
0
Update: Investigation of bioterrorism-related anthrax and adverse events from antimicrobial prophylaxis
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
CDC and state and local public health authorities continue to investigate cases of bioterrorism-related anthrax. As of November 7, a total of 22 cases of anthrax have been identified according to the CDC surveillance case definition; 10 were confirmed inhalational anthrax cases and 12 cases (seven confirmed and five su...
16,804
1
Pathogenetic considerations in ischemic necrosis of bone
DOD - Acute Comp Syndrome CPG
Many factors must be considered in the pathogenesis of ischemic necrosis of bone. Etiologic considerations deal with the heterogeneous disease categories that are associated with bone necrosis; these may affect bone circulation either directly or indirectly on either the arterial or the venous side. Moreover, the compa...
64,868
0
Comparison between intravenous and subcutaneous recombinant human erythropoietin (Epoetin alfa) administration in presurgical autologous blood donation in anemic rheumatoid arthritis patients undergoing major orthopedic surgery
Surgical Management of Osteoarthritis of the Knee CPG
BACKGROUND AND OBJECTIVES: Intravenous (i.v.) Recombinant erythropoietin (Epoetin alfa) is effective in allowing autologous blood donation in patients unable to donate because of anemia. We undertook this open pilot study in order to asses whether a low subcutaneous (s.c.) dose of Epoetin alfa would prove as effective ...
31,097
0
Predisposing factors in fixation failure of femoral prostheses following primary Charnley low friction arthroplasty. A 10- to 20-year followup study
Management of Hip Fractures in the Elderly
To identify factors affecting radiologically detected loosening of the Charnley femoral prosthesis, 326 femoral prostheses with 10- to 20-year followup were studied. After observation of postoperative radiological changes, the criteria for fixation failure detected radiologically, of femoral prostheses were defined as ...
6,265
0
Posterior minimally invasive plate osteosynthesis for humeral shaft fractures
DoD SSI (Surgical Site Infections)
Fractures of the humeral shaft are common. Most of them can be successfully treated without surgery. In some cases, an operative intervention may offer faster and better functional results. One of the major problems with the open plating osteosynthesis is the extensive soft tissue stripping and disruption of periosteal...
147,260
0
Cultural competency and nursing care: an Australian perspective
Management of Hip Fractures in the Elderly
AIMS: To propose a process that will facilitate cultural competence in Australian nursing practice. BACKGROUND: Cultural diversity is a prominent feature of the Australian health system and is impacting significantly on nursing care quality. A fictitious, but typical clinical exemplar is profiled that identifies cultur...
2,760
0
Cohort differences and chronic disease profiles of differential disability trajectories
Management of Hip Fractures in the Elderly
OBJECTIVES: Research shows declining disability rates, but little is known about whether cohort differences are due to delayed onset, increased recovery, or reduced severity of impairment. Furthermore, disease is considered the proximate cause of disability yet chronic conditions rates are increasing, making it unclear...
10,036
0
The treatment of the acute Essex-Lopresti injury
Distal Radius Fractures
The Essex-Lopresti injury (ELI) of the forearm is a rare and serious condition which is often overlooked, leading to a poor outcome. The purpose of this retrospective case study was to establish whether early surgery can give good medium-term results. From a group of 295 patients with a fracture of the radial head, 12 ...
119,831
1
A randomized prospective study on the treatment of intra-articular distal radius fractures: open reduction and internal fixation with dorsal plating versus mini open reduction, percutaneous fixation, and external fixation
Distal Radius Fractures
PURPOSE: To compare 2 methods of surgical treatment for displaced intra-articular fractures of the distal radius: open reduction and internal fixation with dorsal plating (Pi Plate; Synthes, Paoli, PA) versus mini open reduction with percutaneous K-wire and external fixation. METHODS: Patients with AO type C intra-arti...
122,864
0
Obesity and other modifiable factors for physical inactivity measured by accelerometer in adults with knee osteoarthritis
Surgical Management of Osteoarthritis of the Knee CPG
Objective To investigate the public health impact of obesity and other modifiable risk factors related to physical inactivity in adults with knee osteoarthritis (OA). Methods The frequency of inactivity as defined by the US Department of Health and Human Services was assessed from objective accelerometer monitoring of ...
32,477
0
Functional and phenotypical analysis of IL-6-secreting CD4<sup>+</sup> T cells in human adipose tissue
OAK 3 - Non-arthroplasty tx of OAK
Emerging evidence indicates that a dynamic interplay between the immune system and adipocytes contributes to the disturbed homeostasis in adipose tissue of obese subjects. Recently, we observed IL-6-secretion by CD4<sup>+</sup> T cells from the stromal vascular fraction (SVF) of the infrapatellar fat pad (IFP) of knee ...
108,227
0
T1rho Magnetic Resonance Imaging at 3T Detects Knee Cartilage Changes After Viscosupplementation
OAK 3 - Non-arthroplasty tx of OAK
Viscosupplementation may affect cartilage. Changes in T1rho magnetic resonance imaging (MRI) relaxation times correlate with proteoglycan changes in cartilage. The authors hypothesized that T1rho MRI will show an improvement in proteoglycan content at 6 weeks and 3 months after viscosupplementation and that this improv...
101,372
0
Relationship between serum 2 5-hydoroxyvitamin D levels and prevalent fracture risk in postmenopausalwomen
Management of Hip Fractures in the Elderly
Aim: Vitamin D insufficiency is frequently observed in general population, especially in elderly. The importance of vitamin D status in bone health has been noted. Vitamin D insufficiency is associated with an increase in PTH, which might be critical for an increase in bone fragility. However, the role of endogenous PT...
11,592
1
Bacteriology swab in primary total hip arthroplasty-- does it have a role?
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Infection in joint replacement is a devastating complication, and in spite of the advances in surgery, it remains a challenge. The rate of deep infection following primary hip/knee arthroplasty is between 1% and 2%. The aim of this study was to determine whether obtaining bacteriology swabs at the time of surgery could...
22,170
0
Absolute monocytosis at diagnosis correlates with survival in diffuse large B-cell lymphoma-possible link with monocytic myeloid-derived suppressor cells
MSTS 2022 - Metastatic Disease of the Humerus
Some patients with lymphoma have monocytosis at diagnosis, but its significance is unclear. The recently recognized subpopulation, monocytic myeloid-derived suppressor cells (M-MDSCs), has immunoregulatory function, suppresses host anti-tumour immunity and plays a role in cancer tolerance. Data from 91 untreated patien...
155,659
0
Elbow arthroplasty for the treatment of bicolumn distal humeral fractures
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
Distal humeral fractures are difficult to treat in elderly patients. Recent advances in precontoured and locked plates have made open reduction and internal fixation easier, but rigid and anatomic reconstruction is required for a successful result. In elderly patients with poor bone quality and an unreconstructable art...
22,752
0
Unusual complications of knee replacement surgery in a severe hemophilia B patient with high titer inhibitor
Surgical Management of Osteoarthritis of the Knee CPG
Background: Treatment of bleeding in hemophilia B patients with inhibitors is based on bypassing the intrinsic pathway or overwhelming the inhibitor with high-dose factor IX concentrates. For major surgery, these strategies may be unsuccessful or avoided to prevent venous thromboembolism (VTE). For patients who have fa...
26,174
0
Efficacy of continued alendronate for fractures in women with and without prevalent vertebral fracture: the FLEX trial
Management of Hip Fractures in the Elderly
In the Fracture Intervention Trial (FIT) Long Term Extension (FLEX) Trial, 10 years of alendronate (ALN) did not significantly reduce the risk of nonvertebral fractures (NVFs) compared with 5 years of ALN. Continuing ALN reduced the risk of clinical but not morphometric vertebral fractures regardless of baseline verteb...
9,787
1
Primary hemiarthroplasty in old patients with displaced femoral neck fracture: a 1-year follow-up of 103 patients aged 80 years or more
Management of Hip Fractures in the Elderly
103 patients with displaced femoral neck fractures (Garden 3-4) treated with primary hemiarthroplasty in the Department of Orthopedics, Malmo University Hospital, Sweden 1998-1999 were followed in a prospective, consecutive study for 1 year. Inclusion criteria were age of at least 80 years, signs of mental changes and/...
14,731
0
Musculo-skeletal manifestations of haemophilia
OAK 3 - Non-arthroplasty tx of OAK
Haemophilia left untreated or treated on demand destroys the joints at a very young age. Primary haematological prophylaxis, currently the gold standard for the treatment of haemophilia, is not completely effective. Moreover, it is only available for 25â??30% of patients worldwide. Advances in haematology, combined wit...
104,401
0
2017 American College of Rheumatology/American Association of Hip and Knee Surgeons Guideline for the Perioperative Management of Antirheumatic Medication in Patients With Rheumatic Diseases Undergoing Elective Total Hip or Total Knee Arthroplasty
AAHKS (2) Corticosteroids
OBJECTIVE: This collaboration between the American College of Rheumatology and the American Association of Hip and Knee Surgeons developed an evidence-based guideline for the perioperative management of antirheumatic drug therapy for adults with rheumatoid arthritis (RA), spondyloarthritis (SpA) including ankylosing sp...
84,690
0
Selective augmentation of stem cell populations in structural fat grafts for maxillofacial surgery
Panniculectomy & Abdominoplasty CPG
Structural fat grafting utilizes the centrifugation of liposuction aspirates to create a graded density of adipose tissue. This study was performed to qualitatively investigate the effects of centrifugation on stem cells present in adipose tissue. Liposuction aspirates were obtained from healthy donors and either not c...
127,178
0
Bone mineral density in patients on maintenance hemodialysis and effect of chronic hepatitis C virus infection
Management of Hip Fractures in the Elderly
OBJECTIVE: To determine the prevalence of osteopenia and osteoporosis in HD patients at our center; to investigate whether HCV infection affects BMD in hemodialysis patients; to test for correlations between bone mineral density (BMD) and clinical and laboratory parameters in this population. SUBJECTS AND METHODS: The ...
11,712
0
Protelos: nonvertebral and hip antifracture efficacy in postmenopausal osteoporosis
Management of Hip Fractures in the Elderly
Strontium ranelate is a new treatment for postmenopausal osteoporosis, simultaneously increasing bone formation and decreasing bone resorption, thus rebalancing bone turnover in favor of bone formation. Strontium ranelate was demonstrated to significantly reduce the relative risk of vertebral fracture whatever the seve...
1,228
0
Single Shot vs 24hr vs 48hr Continuous Adductor Canal Block After TKA
OAK 3 - Non-arthroplasty tx of OAK
If the patient is willing to participate and signs the consent, he/she will be randomized to one of the three treatment groups: 1. Single shot block 2. 24 hour catheter 3. 48 hour catheter The choice of anesthetic technique will be at the discretion of the anesthesiologist. In our institution we usually advocate for sp...
106,586
0
Establishment of a transplantable rat pulmonary carcinoma-derived cell line (IP-B12) as a new model of humoral hypercalcemia of malignancy and bone metastasis
MSTS 2018 - Femur Mets and MM
A cloned cell line (IP-B12) derived from a transplantable rat pulmonary carcinoma (IP), of which neoplastic cells produce parathyroid hormone-related protein (PTHrP), was established. Tumors induced in syngeneic F344 rats by intraperitoneal injection of IP-B12 cells had features of pulmonary adenocarcinomas, consisting...
76,426
0
Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing
Management of Hip Fractures in the Elderly
Fracture healing is orchestrated by a specific set of events that culminates in the repair of bone and reachievement of its biomechanical properties. The aim of our work was to study the sequence of gene expression events involved in inflammation and bone remodeling occurring in the early phases of callus formation in ...
3,132
0
Report on the Japanese Orthopaedic Association's 3-year project observing hip fractures at fixed-point hospitals
Management of Hip Fractures in the Elderly
BACKGROUND: The aim of this study was to assess the disability and mortality of hip fractures 1 year after initial visit (postoperatively) at fixed-point hospitals selected by the Japanese Orthopaedic Association Committee on Osteoporosis. METHOD: A total of 158 core orthopedic hospitals were selected for participation...
9,498
0
The use of near-infrared spectrometry for the diagnosis of lowerextremity compartment syndrome
DOD - Acute Comp Syndrome CPG
While intracompartmental pressure monitoring is a widely used diagnostic tool to measure intracompartmental pressures in the setting of compartment syndrome, its invasive nature has prompted the development of noninvasive techniques, such as near-infrared spectrometry. We prospectively assessed the association between ...
63,581
0
Long-term follow up of single-stage anterior cruciate ligament reconstruction and high tibial osteotomy and its relation with posterior tibial slope
OAK 3 - Non-arthroplasty tx of OAK
BACKGROUND: Open-wedge high tibial osteotomy is considered to be an effective treatment for medial compartmental osteoarthritis. It is generally admitted that tibial slope increases after open-wedge high tibial osteotomy and decreases after closing-wedge high tibial osteotomy. Young patients with anterior cruciate liga...
101,291
0
A protocol for staged arthroplasty to salvage infected nonunion of hip fractures
DoD SSI (Surgical Site Infections)
BACKGROUND: Nonunion of hip fractures is not uncommon. Total hip arthroplasty is used to salvage cases of non union or secondary arthritis in these fractures. However, this option may not be available or may be difficult to achieve when infection has superseded the site of nonunion. The objective of this prospective st...
149,899
0
Partial versus Intact Posterior Cruciate Ligament-retaining Total Knee Arthroplasty: a Comparative Study of Early Clinical Outcomes
DoD SSI (Surgical Site Infections)
OBJECTIVE: Whether the entire posterior cruciate ligament (PCL) should be retained during cruciate-retaining total knee arthroplasty (CR TKA) is controversial. The goal of this study was to compare the early clinical outcomes of partial versus intact PCL-retaining TKA. METHODS: Ninety-two patients who had undergone uni...
150,579
1
Clinical Outcome Differences in the Treatment of Impending Versus Completed Pathological Long-Bone Fractures
MSTS 2022 - Metastatic Disease of the Humerus
BACKGROUND: The outcome differences following surgery for an impending versus a completed pathological fracture have not been clearly defined. The purpose of the present study was to assess differences in outcomes following the surgical treatment of impending versus completed pathological fractures in patients with lon...
157,410
0
Double Tension Band Osteosynthesis in Inter-Condylar Humeral Fractures
Pediatric Supracondylar Humerus Fracture 2020 Review
INTRODUCTION: Intercondylar humerus fractures are uncommon in orthopaedic practice. The treatment for the same has been described in the literature and include paragonal and orthogonal fixation by using plates. Tension band wiring as a treatment for the same is sparsely described in the literature. AIM: To evaluate the...
141,738
0
Immunohistochemical detection of nm23/NDP kinase and cathepsin D in medullary carcinomas of the thyroid gland
MSTS 2018 - Femur Mets and MM
Reduced expression of nm23/NDP kinase and increased expression of cathepsin D seem to be correlated with the high metastatic potential in a variety of malignancies. The expression of nm23/NDP kinase and that of cathepsin D have been evaluated by means of an immunohistochemical technique in paraffin-embedded tissues fro...
78,828
0
Effects of squat lift training and free weight muscle training on maximum lifting load and isolinetic peak torque of young adults without impairments
The Treatment of Pediatric Supracondylar Humerus Fractures AUC
BACKGROUND AND PURPOSE: Manual lifting is a frequent cause of back injury, and there is no evidence as to which training mode can provide the best training effect for lifting performance and muscle force. The purpose of this study was to examine the effects of a squat lift training and a free weight muscle training pro...
24,148
1
Improvement in aerobic fitness during rehabilitation after hip fracture
Management of Hip Fractures in the Elderly
OBJECTIVE: To evaluate the effect of an upper-body exercise program on cardiorespiratory fitness in older adults with hip fracture during inpatient rehabilitation. DESIGN: Randomized controlled trial using a convenience sample. SETTING: An inpatient rehabilitation unit. PARTICIPANTS: Twenty older patients (age, 81.3+/-...
14,428
0
Identification of streptococcus mitis group species by RFLP of the PCR-amplified 16S-23S rDNA intergenic spacer
Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures
Mitis group streptococci are pioneer colonizers of tooth surfaces and are implicated in various pathologies. Thus, accurate identification of oral mitis group strains would be valuable for studies of plaque ecology and dental caries and for diagnostic use in endocarditis or sepsis patients. The aim of this study was to...
17,072
0
External Fixator-assisted Ulnar Osteotomy: A Novel Technique to Treat Missed Monteggia Fracture in Children
DoD SSI (Surgical Site Infections)
OBJECTIVE: The treatment of missed Monteggia fracture remains a challenge, despite the various surgical methods described. The purpose of this study was to explore a new surgical technique utilizing external fixator-assisted ulnar osteotomy and to assess the surgical results in a case series. METHODS: Thirteen patients...
150,658
0
Finite schematic eye models and their accuracy to in-vivo data
Upper Eyelid and Brow Surgery
Measurement of ocular wavefront aberration is becoming a popular clinical technique due to recent technical advances and an increasing awareness of its potential for practical application in the fields of surgical and optical refractive correction. In addition, information about the status of peripheral refraction dete...
66,515
0
Fluoroscopy cannot recognize intraoperative fracture in patients receiving 2-incision total hip arthroplasty
Management of Hip Fractures in the Elderly
Intraoperative fluoroscopy is suggested as a standard procedure in 2-incision total hip arthroplasty. Between September 2003 and July 2004, 2-incision total hip arthroplasties were done in 18 hips with and another 18 hips without the use of fluoroscopy. In group 1, the anterior skin incision was initially limited to 5 ...
4,873
0
Are the Outcomes of Revision Knee Arthroplasty for Flexion Instability the Same as for Other Major Failure Mechanisms?
OAK 3 - Non-arthroplasty tx of OAK
Background Aseptic loosening, infection, and flexion instability have emerged as the leading etiologies for revision after total knee arthroplasty (TKA). Although studies have reported improved outcomes after revision TKA, the relative functional and clinical outcomes of patients revised for flexion instability and oth...
112,294
0
Scintigraphy with 99mTc-phosphonate and 67gallium in patients suspected of primary bone tumors
MSTS 2018 - Femur Mets and MM
Whole-body scintigraphy with both 99mTc-phosphonate and 67Ga was performed on 92 patients suspected of primary bone tumors. In 46 patients with primary malignant bone tumors, scintigraphy with 99mTc-phosphonate disclosed the primary tumor in 44 cases and skeletal metastases in 11, and 67Ga scintigraphy detected the pri...
78,294
0
Clinical impact of matrix metalloproteinase-7 mRNA expression in the invasive front and inner surface of tumor tissues in patients with colorectal cancer
MSTS 2018 - Femur Mets and MM
PURPOSE: Matrix metalloproteinase-7, reversion-inducing cysteine-rich protein with Kazal motifs, chemokine receptor 7, and vascular endothelial growth factor-C have been correlated with tumor invasion and lymph node metastasis in patients with gastrointestinal cancer. Our study of patients with colorectal cancer quanti...
78,795
0
In Vitro Validation of a Closed Device Enabling the Purification of the Fluid Portion of Liposuction Aspirates
Panniculectomy & Abdominoplasty CPG
BACKGROUND: Adipose tissue harvested through lipoaspiration is widely exploited in plastic and cosmetic surgery, because of its remarkable trophic properties, especially relying on the presence of adipose-derived stem cells. The common procedures for adipose-derived stem cell isolation are mainly based on tissue fracti...
125,538
0
Improving Tibial Component Coronal Alignment During Total Knee Arthroplasty with the Use of a Double-Check Technique
OAK 3 - Non-arthroplasty tx of OAK
Objective: To compare the efficacy of the restoration of tibial component coronal alignment with a double-check technique and the conventional surgical technique during total knee arthroplasty (TKA) in knee osteoarthritis patients, and to investigate the distribution of the medial proximal tibial angle (MPTA) after TKA...
113,822
0
The association of AKNA gene polymorphisms with knee osteoarthritis suggests the relevance of this immune response regulator in the disease genetic susceptibility
OAK 3 - Non-arthroplasty tx of OAK
Recent studies have identified AKNA as a potential susceptibility gene for several inflammatory diseases. Here, we aimed to assess the potential association of AKNA polymorphisms with knee osteoarthritis (KOA) susceptibility in a Mexican population, following STREGA recommendations. From a DNA bank of 181 KOA patients ...
102,176
0
Early effect of hyaluronic acid intra-articular injections on serum and urine biomarkers in patients with knee osteoarthritis: An open-label observational prospective study
OAK 3 - Non-arthroplasty tx of OAK
The aim of the study was to investigate the effect of hyaluronic acid (HA) intra articular injections (IA) on osteoarthritis (OA) biomarkers in patients with knee OA. Prospective open label study. Fifty-one patients with unilateral symptomatic K-OA received IA injections of 2mL of HA on days (D) 1, 7, 14 and were follo...
109,932
0
Oncologic emergencies
MSTS 2018 - Femur Mets and MM
Objectives: To provide an up-to-date review of current literature on the pathophysiology, diagnosis, and management of five key malignancy-related complications: superior vena cava syndrome, malignant pericardial effusion, malignant spinal cord compression, hypercalcemia, and acute tumor lysis syndrome. Data Sources: D...
83,259
0
Fracture-pattern-related therapy concepts in distal humeral fractures
Distal Radius Fractures
Around one third of humeral fractures and 2-6% of all fractures occur to the distal part of the humerus. There is a bimodal distribution differentiating between young male patients with high-energy and elderly female patients with low-energy trauma related to osteoporosis. The AO classification and Dubberley subclassif...
121,211
1
Medication safety: does intravenous acetaminophen promote perioperative hypothermia for total hip arthroplasty?
AAHKS (4) Acetaminophen
As an effective antipyretic with a yet-unknown mechanism-of-action, intravenous (IV) acetaminophen use for total hip arthroplasties (THA) may worsen perioperative hypothermia when combined with the known hypothermia-inducing effects of general anesthesia (GA), affecting wound healing, recovery times, and patient satisf...
97,477
0
The thrust plate prosthesis in the treatment of osteoarthritis of the hip. Clinical and radiological outcome with minimum 5-year follow-up
Management of Hip Fractures in the Elderly
The thrust plate prosthesis (TPP) is a neck preserving femoral component in total hip arthroplasty (THA). We present our mid-term results from using the thrust plate prosthesis in young patients with hip arthritis. We conducted a retrospective review of a consecutive series of patients with a minimum of 5 years follow-...
2,642
0
Closure of patent foramen ovale for paradoxical emboli: intermediate-term risk of recurrent neurological events following transcatheter device placement
Management of Hip Fractures in the Elderly
OBJECTIVES: We report the largest and the longest follow-up to date of patients who underwent transcatheter patent foramen ovale (PFO) closure for paradoxical embolism. BACKGROUND: Closure of a PFO has been proposed as an alternative to anticoagulation in patients with presumed paradoxical emboli. METHODS: Data were co...
4,926
0
Surgical approaches to the humeral shaft
Distal Radius Fractures
Open fractures, transverse, short oblique and spiroid fractures of the humeral shaft, as well as comminuted fractures with radial palsy or vascular injury, mostly lead to bad end-results if treated conservatively. The same is valid in the case of bilateral humeral shaft fractures, multiple injuries, polytrauma, patholo...
118,990
0
Monoclonal antibodies for medical oncology: A few critical perspectives
MSTS 2018 - Femur Mets and MM
Incorporation of antibodies as weapons for cancer therapy has meant a turning point in the survival, clinical and radiological response of many oncology patients. These drugs are effective, well designed missiles that either alone or in combination with chemotherapy are unavoidable weapons for breast, lung and colon ca...
77,577
0
Rheumatoid Arthritis of the Elbow
Pediatric Supracondylar Humerus Fracture 2020 Review
Rheumatoid arthritis (RA) is the most common form of inflammatory arthropathy. RA is considered a disease of synovial joints, although it can cause various extra-articular manifestations. The synovium appears to be the primary target; however, investigations are ongoing to determine the exact etiology and pathoanatomy....
141,410
0
Study of Cartilage Relaxometry and Physical Activity in Osteoarthritis
OAK 3 - Non-arthroplasty tx of OAK
This study is the radiological component of an earlier registered RCT under the title: Efficacy of Exercise on Physical Function and Cartilage Health in Patients With Knee Osteoarthritis. The main purpose in this component of the study is to evaluate the efficacy of aerobic exercise and strength training on the T2 and ...
106,638
0
Adipose tissue derived stem cells: in vitro and in vivo analysis of a standard and three commercially available cell-assisted lipotransfer techniques
Panniculectomy & Abdominoplasty CPG
INTRODUCTION: Autologous fat grafting is commonly used to correct soft-tissue contour deformities. However, results are impaired by a variable and unpredictable resorption rate. Autologous adipose-derived stromal cells in combination with lipoinjection (cell-assisted lipotransfer) seem to favor a long-term persistence ...
125,347
0
Late dorsal tilt angulation of distal articular surface of radius in Colles' type of fracture at the end of the immobilization, can it be predicted?
Distal Radius Fractures
BACKGROUND: The objective was to predict the late dorsal tilt angulation of distal articular surface of radius in Colles' type of fracture with radioulna index difference, age, sex of the patient and dorsal cortex comminution. MATERIAL AND METHOD: Correlation between previously mentioned factors and the changing degree...
117,991
0
Concurrent fractures of the hip and wrist: a matched analysis of elderly patients
Distal Radius Fractures
INTRODUCTION: Osteoporotic fractures involving the hip and wrist are common in the elderly. The incidence of coincident hip and wrist fractures in the same patient is small but may represent a unique subpopulation of elderly with osteoporotic fragility fractures and little information has been published about these pat...
118,300
1
Infection after intramedullary nailing of severe open tibial fractures initially treated with external fixation
DoD SSI (Surgical Site Infections)
Twenty-four patients had a severe open fracture of the tibia that was initially treated by external fixation and subsequently by reamed intramedullary nailing. The external fixation had been maintained for an average of fifty-two days (range, seven to 230 days). The mean interval between removal of the external fixator...
151,755
0
Does the type of flooring affect the risk of hip fracture?
Management of Hip Fractures in the Elderly
BACKGROUND: The number of hip fractures occurring worldwide in 1990 was estimated at 1.7 million and is predicted to rise to 6.3 million by 2050. The vast majority occur as a result of simple falls and the impact of the femoral trochanter with the floor. Previous studies have addressed the problem from the patient's si...
10,724
0
Prediction of perimenopausal fractures by bone mineral density and other risk factors
Management of Hip Fractures in the Elderly
In a prospective population-based cohort study, we assessed whether bone mineral density (BMD) measurements of perimenopausal women and other risk factors for osteoporosis are predictive of subsequent fracture. Women aged 47-51 years chosen randomly from a population register who underwent a bone density measurement 2 ...
10,136
0
Effect of therapist-based versus robot-assisted bilateral arm training on motor control, functional performance, and quality of life after chronic stroke: a clinical trial
Pediatric Supracondylar Humerus Fracture 2020 Review
BACKGROUND: Although bilateral arm training (BAT) has been widely studied, the comparative effects of therapist-based BAT (TBAT) versus robot-assisted BAT (RBAT) remains unknown. OBJECTIVE: This study compared the efficacy of TBAT, RBAT, and a control treatment (CT) on motor control, functional performance, and quality...
141,290
0
Registration of arthroplasties in Finland. A nationwide prospective project
Surgical Management of Osteoarthritis of the Knee CPG
Data on hip and knee arthroplasties have been compiled on a nationwide basis in Finland since 1980. Forty-five major departments contribute to the study providing data on the type of operation, the implant used, the diagnosis, and the 1-year clinical results. In the case of revision, new data are sent to the register, ...
35,727
0
Bone disease from monoclonal gammopathy of undetermined significance to multiple myeloma: pathogenesis, interventions, and future opportunities
MSTS 2018 - Femur Mets and MM
Manifestations of bone disease-osteopenia, osteolytic lesions, and fractures-are the hallmark of multiple myeloma (MM) and occur clinically in the vast majority of patients. These abnormalities can have devastating clinical effects by increasing both the morbidity and mortality of patients. Bone disease is usually foun...
82,518
1
Knee arthroscopy and arthrotomy under local anesthesia
Surgical Management of Osteoarthritis of the Knee CPG
We report our experience with knee arthroscopy in local anesthesia in 64 patients with subsequent arthrotomy in 14 of these. The effectiveness of the anesthetic method was evaluated by both the patient and the anesthetic personnel. There was no difference in pain assessment between arthroscopy alone and arthroscopy fol...
38,166
0
Activation of coagulation and deep vein thrombosis after bone marrow harvesting and insertion of a Hickman-catheter in ABMT patients with malignant lymphoma
MSTS 2022 - Metastatic Disease of the Humerus
Evidence of activation of coagulation was sought in serial plasma samples from 25 ABMT candidates with malignant lymphoma admitted for bone marrow harvesting: 10 females and 15 males, median age 41 years (range 27-58 years). Nineteen patients had non-Hodgkin's lymphoma (NHL) and six had Hodgkin's disease. Of those with...
155,720
0
Influence of hemianopic visual field loss on visual motor control
Upper Eyelid and Brow Surgery
BACKGROUND: Homonymous hemianopia (HH) is an anisotropic visual impairment characterized by the binocular inability to see one side of the visual field. Patients with HH often misperceive visual space. Here we investigated how HH affects visual motor control. METHODS AND FINDINGS: Seven patients with complete HH and no...
66,859
0
Preventing the development of complex regional pain syndrome after surgery
AAHKS (2) Corticosteroids
The development of complex regional pain syndrome after orthopedic surgery is not uncommon. This article reviews the regional nerve blocks and pharmacologic therapies that may be beneficial in reducing the perioperative incidence of complex regional pain syndrome.
85,725
0
Risk factors for development of heterotopic ossification of the elbow after fracture fixation
Pediatric Supracondylar Humerus Fracture 2020 Review
BACKGROUND: Postoperative heterotopic ossification (HO) about the elbow may occur after surgical fixation of fractures and can contribute to dysfunction. Factors associated with HO formation after surgical fixation of elbow trauma are not well understood. METHODS: All patients who underwent surgery for elbow trauma at ...
141,891
0
Multiple Nonspecific Sites of Joint Pain Outside the Knees Develop in Persons With Knee Pain
OAK 3 - Non-arthroplasty tx of OAK
Objective: Many persons with knee pain have joint pain outside the knee, but despite the impact and high frequency of this pain, its distribution and causes have not been studied. We undertook this study to test the hypothesis of those studying gait abnormalities who have suggested that knee pain causes pain in adjacen...
112,129
0
Early serum IGF-I response to oral protein supplements in elderly women with a recent hip fracture
Management of Hip Fractures in the Elderly
BACKGROUND & AIMS: In patients with recent hip fracture, reduced serum IGF-I in relation to protein undernutrition is frequent. Elevation of circulating IGF-I in response to a daily oral supplement of 20 g of casein was observed after 6 months. This study determined if the response to casein as compared to whey protein...
2,794
0
Does the combination of a simultaneous subcapital fracture of humerus and hip fracture in elderly patients carry a prognostic value?
Distal Radius Fractures
The most important factor to cause hip fractures in elderly is probably osteoporosis. Other factors are the increase in fall frequency and the protective response to trauma. Osteoporotic fractures occur most commonly, at the hip, vertebra, distal radius and proximal humerus. A combination of these is uncommon. Thirty-t...
119,594
0
CC chemokine receptor-like 1 functions as a tumour suppressor by impairing CCR7-related chemotaxis in hepatocellular carcinoma
MSTS 2018 - Femur Mets and MM
Atypical chemokine receptors (ACRs) have been discovered to participate in the regulation of tumour behaviour. Here we report a tumour-suppressive role of a novel ACR member, CC chemokine receptor like 1 (CCRL1), in human hepatocellular carcinoma (HCC). Both mRNA and protein expressions of CCRL1 correlated with the mal...
81,219