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Personal, Small Business Banking & Investing
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TD Canada Trust products and services include investing, mortgages, banking and small business. Featuring TD Canada Trust online banking
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Opening TD logo animation. We open on a dad in the kitchen. His ten-year-old son stands next to him. SON: Hey dad? DAD: Yeah, sport? SON: Can we talk about your financial plan to pay for my education? We’re now at a standing dinner party in another house. A friend of the host looks around, enamored with the house,...
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Our history
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Explore the history of the Commonwealth using the interactive timeline.
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Commonwealth
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The Commonwealth is one of the world’s oldest political associations of states. Its roots go back to the British Empire, when countries around the world were ruled by Britain. The early Commonwealth Over time different countries of the British Empire gained different levels of freedom from Britain. Semi-independent c...
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No Newfoundland? :: Hearts of Iron IV General Discussions
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Hoi4 seems to have more than a few problems. I went into it after playing EU4 thinking there would be tonnes of possibilities, but I find out they couldn't even get a 1936 map right. The Dominion of Newfoundland is missing along with other countries. I've found 2 mods which add Newfoundland in, but they screw up other ...
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Nfld Philately 1
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Newfoundland Philately BNAPS Newfoundland Study Group Page 1 of 2 Introduction "Newfoundland was a self-governing Dominion of the British Empire from 1855-1933, when it became a Crown Colony. In 1949 it united with Canada". - Scott Classic Stamp Catalogue, 2002 Newfoundland and Labrador are one province of Canada....
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https://journals.lib.unb.ca/index.php/acadiensis/article/view/18561/20144
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View of Producers versus Profiteers: The Politics of Class in Newfoundland during the First World War
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https://countries.fandom.com/wiki/Dominion_of_Newfoundland
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Dominion of Newfoundland
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The Dominion of Newfoundland was a dominion of the United Kingdom in North America.  Canada (Commonwealth realm)  British America (1607-1783)  United Kingdom: British North America (1783-1907)  Canada (From 1867)  United States World Statesmen.org Wikisource 1911 encyclopedia project Wikipedia
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The Countries Wiki
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Dominion of the ‌United Kingdom ← 1907–1949 → → Motto Quaerite Prime Regnum Dei Seek ye first the kingdom of God Anthem Ode to Newfoundland Capital St. John's Status Dominion Legislature House of Assembly History - Dominion - Newfoundland Act Currency Newfoundland dollar British North America Canada Newfoundland...
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GOVERNMENT OF NEWFOUNDLAND Paper Money, 1901
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GOVERNMENT OF NEWFOUNDLAND Paper Money, 1901-20
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Currency History: GBR until 1858; NFL 1850 - 1949; CAN 1949 > The first banknote attritutable to NFL was issued as P.A3 1 Pound 1850 Newfoundland became a Province of Canada 1.4.1949
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https://www.bankofcanadamuseum.ca/2024/03/welcoming-newfoundland-to-canada/
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Welcoming Newfoundland to Canada
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2024-03-25T00:00:00
Newfoundland’s entry into Confederation marked the end of an era when Canadian provinces issued their own coins and paper money.
en
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How Newfoundland lost its money by joining Confederation The last vestiges of Newfoundland’s currency disappeared with the signing of the Terms of Union. Newfoundland’s entry into Confederation marked the end of an era when colonies issued their own coins and paper money. Newfoundland: island of cod When John Cabot ...
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https://countries.fandom.com/wiki/Dominion_of_Newfoundland
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Dominion of Newfoundland
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The Dominion of Newfoundland was a dominion of the United Kingdom in North America.  Canada (Commonwealth realm)  British America (1607-1783)  United Kingdom: British North America (1783-1907)  Canada (From 1867)  United States World Statesmen.org Wikisource 1911 encyclopedia project Wikipedia
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The Countries Wiki
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Dominion of the ‌United Kingdom ← 1907–1949 → → Motto Quaerite Prime Regnum Dei Seek ye first the kingdom of God Anthem Ode to Newfoundland Capital St. John's Status Dominion Legislature House of Assembly History - Dominion - Newfoundland Act Currency Newfoundland dollar British North America Canada Newfoundland...
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https://www.alternatehistory.com/forum/threads/britain-retains-newfoundland.524396/
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Britain retains Newfoundland
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[ "Reflection" ]
2022-02-14T15:17:54+00:00
Is it feasible for the island of Newfoundland off of Canada's coast to remain British, and not be incorporated into Canada (as part of Newfoundland and...
en
alternatehistory.com
https://www.alternatehistory.com/forum/threads/britain-retains-newfoundland.524396/
Is it feasible for the island of Newfoundland off of Canada's coast to remain British, and not be incorporated into Canada (as part of Newfoundland and Labrador)? I feel like the UK would've liked to have retained an American exclave even in the process of decolonization, due to the advantages it brings in resources, e...
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https://en.wikipedia.org/wiki/Coins_of_the_Newfoundland_dollar
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Coins of the Newfoundland dollar
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[ "Contributors to Wikimedia projects" ]
2005-12-01T02:32:20+00:00
en
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https://en.wikipedia.org/wiki/Coins_of_the_Newfoundland_dollar
See also: Newfoundland dollar Newfoundland, as a separate British colony, produced its own decimal currency between 1865 and 1947. The Coins of Newfoundland are of historical importance as Newfoundland was a British colony until 1907, and a Dominion until 1949, when Newfoundland and Labrador became the tenth province ...
9201
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https://bnaps.org/studygroups/Newfoundland/newfie_intro.htm
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Nfld Philately 1
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en
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Newfoundland Philately BNAPS Newfoundland Study Group Page 1 of 2 Introduction "Newfoundland was a self-governing Dominion of the British Empire from 1855-1933, when it became a Crown Colony. In 1949 it united with Canada". - Scott Classic Stamp Catalogue, 2002 Newfoundland and Labrador are one province of Canada....
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https://stampaday.wordpress.com/2017/04/26/newfoundland-270-1947/
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Newfoundland #270 (1947)
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[ "" ]
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[ "Mark Joseph Jochim" ]
2017-04-26T00:00:00
Newfoundland was a British dominion from 1907 to 1949. It was situated in northeastern North America along the Atlantic coast and comprised the island of Newfoundland and Labrador on the continental mainland to the northwest, with a combined area of 157,500 square miles (405,212 square kilometers). The dominion's seat ...
en
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A Stamp A Day
https://stampaday.wordpress.com/2017/04/26/newfoundland-270-1947/
Newfoundland was a British dominion from 1907 to 1949. It was situated in northeastern North America along the Atlantic coast and comprised the island of Newfoundland and Labrador on the continental mainland to the northwest, with a combined area of 157,500 square miles (405,212 square kilometers). The dominion’s seat ...
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https://www.wikidata.org/wiki/Q2411666
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Newfoundland dollar
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currency of the Dominion of Newfoundland from 1865 to 1949
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currency of the Dominion of Newfoundland from 1865 to 1949
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https://canadacurrency.com/canadian-banknotes/government-of-newfoundland-1920-banknotes/value-of-january-2nd-1920-government-of-newfoundland-1-bill/
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Value of January 2nd 1920 Government of Newfoundland Value of January 2nd 1920 Government of Newfoundland $1 Bill Bill
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2013-11-22T19:10:41+00:00
Our guide has pictures and prices for all Newfoundland January 2nd 1920 one dollar bank notes. We provide free appraisals and we are also buyers. Please contact us if you want to sell your Canadaian bank note.
en
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Canadian Currency |
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January 2nd 1920 Government of Newfoundland $1 Bill Description: These are very popular bank notes. Each note has a portrait of King George V. The right hand side of the note shows a blue vignette of a caribou. Prices for circulated notes usually range from $100 to $500. High grade notes can be worth significantly mor...
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https://blog.colonialacres.com/history-of-the-two-dollar-canadian-bill/
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The History Of The Two
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[ "Colonial Acres Coins" ]
2021-08-17T12:25:04-04:00
The two-dollar Canadian bill was discontinued 25 years ago, but getting your hands on one now could be worth a lot! Find out where to find them and more here.
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Buy & Sell Royal Canadian Mint Coins - Colonial Acres Coins
https://blog.colonialacres.com/history-of-the-two-dollar-canadian-bill/
Last Updated on May 2, 2024 Posted by Colonial Acres Coins Canada discontinued its two-dollar bill 25 years ago and replaced it with the toonie coin. The government then pulled tender status from this and several other banknotes in 2021. Now, this piece of Canadian paper money can be worth up to tens of thousands of d...
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https://www.facebook.com/Beavercrafts/posts/newfoundland-coins-and-stamps-are-wonderful-keepsakes-of-our-pre-confederation-h/2989214814539454/
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Facebook
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https://countries.fandom.com/wiki/Dominion_of_Newfoundland
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Dominion of Newfoundland
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[ "Contributors to The Countries Wiki" ]
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The Dominion of Newfoundland was a dominion of the United Kingdom in North America.  Canada (Commonwealth realm)  British America (1607-1783)  United Kingdom: British North America (1783-1907)  Canada (From 1867)  United States World Statesmen.org Wikisource 1911 encyclopedia project Wikipedia
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The Countries Wiki
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Dominion of the ‌United Kingdom ← 1907–1949 → → Motto Quaerite Prime Regnum Dei Seek ye first the kingdom of God Anthem Ode to Newfoundland Capital St. John's Status Dominion Legislature House of Assembly History - Dominion - Newfoundland Act Currency Newfoundland dollar British North America Canada Newfoundland...
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Dominion of Newfoundland
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[ "Contributors to The Countries Wiki" ]
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The Dominion of Newfoundland was a dominion of the United Kingdom in North America.  Canada (Commonwealth realm)  British America (1607-1783)  United Kingdom: British North America (1783-1907)  Canada (From 1867)  United States World Statesmen.org Wikisource 1911 encyclopedia project Wikipedia
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The Countries Wiki
https://countries.fandom.com/wiki/Dominion_of_Newfoundland
Dominion of the ‌United Kingdom ← 1907–1949 → → Motto Quaerite Prime Regnum Dei Seek ye first the kingdom of God Anthem Ode to Newfoundland Capital St. John's Status Dominion Legislature House of Assembly History - Dominion - Newfoundland Act Currency Newfoundland dollar British North America Canada Newfoundland...
9201
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http://kpolsson.com/coinhist/canada/
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Chronology of Canadian Coins
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[ "Ken Polsson" ]
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Timeline of events tracing the history of Canada's decimal coinage, both circulating and collector coins.
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1842 April 27 The Currency Act of 1841 comes into effect, making legal tender the British sovereign, and the American eagle ($10), dollar, and half-dollar coins. French crowns and half-crowns are no longer legal tender. [169.230] [1003.36] 1850 Inspector-General for the Province of Canada, Francis Hincks, introduce...
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https://kids.kiddle.co/Coins_of_the_Newfoundland_dollar
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Coins of the Newfoundland dollar facts for kids
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Learn Coins of the Newfoundland dollar facts for kids
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https://kids.kiddle.co/Coins_of_the_Newfoundland_dollar
See also: Newfoundland dollar Newfoundland, as a separate British colony, produced its own decimal currency between 1865 and 1947. The coins of Newfoundland are of historical importance as Newfoundland was a British colony until 1907, and a Dominion until 1949, when Newfoundland and Labrador became the tenth province ...
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https://cartolina.com/products/cartolina-vintage-map-of-the-dominion-of-canada-and-newfoundland
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Cartolina Vintage Map of the Dominion of Canada and Newfoundland
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This vintage map of the Dominion of Canada and Newfoundland is colourful, beautiful, and so interesting!  Printed on heavy paper. 20"H x 28"W Please note: A maximum of 3 maps can fit in each mailing tube for the flat rate of $16.
en
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Cartolina
https://cartolina.com/products/cartolina-vintage-map-of-the-dominion-of-canada-and-newfoundland
This vintage map of the Dominion of Canada and Newfoundland is colourful, beautiful, and so interesting! Printed on heavy paper. 20"H x 28"W
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https://althistory.fandom.com/wiki/Newfoundland_and_Labrador_(Clingy_Britain)
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Newfoundland and Labrador (Clingy Britain)
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[ "" ]
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[ "Contributors to Alternative History" ]
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Newfoundland and Labrador is the largest oversea division of the UK, encompassing 405,212 sq km (including territorial waters). It has a total population of over 500,000, around 40% of whom live in the capital of St. John's. The former colony has its own parliament and acts independently of UK...
en
https://static.wikia.nocookie.net/althistory/images/4/4a/Site-favicon.ico/revision/latest?cb=20210916203836
Alternative History
https://althistory.fandom.com/wiki/Newfoundland_and_Labrador_(Clingy_Britain)
Newfoundland and Labrador is the largest oversea division of the UK, encompassing 405,212 sq km (including territorial waters). It has a total population of over 500,000, around 40% of whom live in the capital of St. John's. The former colony has its own parliament and acts independently of UK proper on most issues. H...
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https://www.worldbanknotescoins.com/2014/12/1920-government-of-newfoundland-1-dollar-bill.html
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World Banknotes & Coins Pictures | Old Money, Foreign Currency Notes, World Paper Money Museum
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Newfoundland dollar January 2nd 1920 Government of Newfoundland $1 Bill 1920 Government of Newfoundland $1 Dollar Bill Obverse: ...
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World Banknotes and Coins, Foreign Currency from Around the World. Old Money, Currency Notes. World Banknote Gallery - Huge collection of world banknotes images pictures with description and tons of information about World Paper Money.
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https://en.wikipedia.org/wiki/Dominion_of_Newfoundland
en
Dominion of Newfoundland
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[ "Contributors to Wikimedia projects" ]
2004-06-01T23:09:31+00:00
en
/static/apple-touch/wikipedia.png
https://en.wikipedia.org/wiki/Dominion_of_Newfoundland
British dominion from 1907 to 1949 Newfoundland was a British dominion in eastern North America, today the modern Canadian province of Newfoundland and Labrador. It was confirmed by the Balfour Declaration of 1926 and the Statute of Westminster of 1931. It included the island of Newfoundland, and Labrador on the conti...
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https://hcmc.uvic.ca/confederation/en/lgHC_NFLD_1949-02-08.html
en
House of Commons, 8 February 1949, Canadian Confederation with Newfoundland
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Abbott, Douglas Charles This individual participated in: 1945: House of Commons as a representative for St. Antoine—Westmount 1949: NF House of Commons as a representative for St. Antoine—Westmount Number of times this person appears in the documents: 4 Debates and documents House of Commons debates on Newfoundlan...
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https://commons.wikimedi…_Cents_1941C.jpg
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File:Canada Newfoundland George VI 10 Cents 1941C.jpg
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1941-08-20T00:00:00
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This work is free and may be used by anyone for any purpose. If you wish to use this content, you do not need to request permission as long as you follow any licensing requirements mentioned on this page. The Wikimedia Foundation has received an e-mail confirming that the copyright holder has approved publication unde...
9201
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81
https://www.cbc.ca/news/canada/newfoundland-labrador/union-part-time-dominion-1.5179587
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'People need to work,' Unifor says as Newfoundland Dominion stores restructure
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[ "CBC News" ]
2019-06-18T14:18:00+00:00
The union says Loblaw is exploiting part-time employees by shouldering them with full-time hours.
en
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CBC
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The union representing Dominion grocery store workers says a recent decision to restructure stores is exploiting part-time employees. In a news release Monday, Unifor, which represents more than 1,200 workers at 11 stores across Newfoundland, said Loblaw Companies Ltd. is offering workers buyout packages. The goal is...
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https://www.economist.com/news/2007/10/12/a-far-country
en
A far country
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[ "" ]
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[ "The Economist" ]
2007-10-12T00:00:00
Nationalist sentiment without a state | News
en
/favicon.ico
The Economist
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https://www.cbc.ca/news/canada/newfoundland-labrador/dominion-strike-loblaw-letter-no-improved-offer-1.5710476
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Loblaw vows no 'improved offer' as Unifor digs in heels on Dominion strike
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[ "" ]
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[ "CBC News" ]
2020-09-03T13:23:00+00:00
The union representing striking Dominion workers has released a letter it was sent from Loblaw, saying there's no better deal to be had than the one already rejected.
en
/a/apple-touch-icon.png
CBC
https://www.cbc.ca/news/canada/newfoundland-labrador/dominion-strike-loblaw-letter-no-improved-offer-1.5710476
The union representing the 1,400 Dominion workers on picket lines across Newfoundland is digging in its heels, after receiving a letter from parent company Loblaw stating there's no better deal to be had than the one already rejected. In a two-page letter, dated Sept. 1, to the workers, Loblaw's Atlantic Canada vice-p...
9201
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https://canadacurrency.com/canadian-banknotes/
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Province of Canada and Newfoundland Government Currency
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[ "province of canada currency", "newfoundland government cash note currency", "prince edward island banknotes" ]
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[]
2013-11-21T20:58:26+00:00
We have a guide for strange and rare banknotes from Canada that fall outside of the main collecting categories. These bank notes, while slightly odd, are still very collectible and sometimes very rare. We provide free appraisals. Contact us for an offer.
en
http://canadacurrency.com/wp-content/uploads/2013/10/canada-flag-Copy.png
Canadian Currency |
https://canadacurrency.com/canadian-banknotes/
Other Types of Collectible Banknotes from Canada Most Canadian banknotes are either from The Bank of Canada (La Banque Du Canada), The Dominion of Canada, or a Canadian chartered bank. However, there are still lots of banknotes that are very rare and valuable that do not fall into one of those three categories. We are...
9201
dbpedia
1
56
https://www.abebooks.com/Dominion-Canada-Newfoundland-Excursion-Alaska-Handbook/31214094817/bd
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The Dominion of Canada with Newfoundland and an Excursion to Alaska: Handbook for Travellers by Baedecker, Karl: Very Good (1907) Third edition.
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1907-08-20T00:00:00
Third edition. - Karl Baedeker, Leipzig, Germany - 1907 - Condition: Very Good - 16mo (6"x4"). 331pp. Red flex covers, blindstamped with giltstamped titles. Marbled textblock edges. 13 full color maps, 5 of which are fold-outs and "12 plans". Light shelfwear: rubbed edges, warp, soiling. Pages toned. Heavily foxed endp...
en
https://www.abebooks.com/Dominion-Canada-Newfoundland-Excursion-Alaska-Handbook/31214094817/bd
Terms of Sale: We guarantee the condition of every book as it's described on the Abebooks web sites. If you're dissatisfied with your purchase (Incorrect Book/Not as Described/Damaged) or if the order hasn't arrived, you're eligible for a refund within 30 days of the estimated delivery date. If you've changed your min...
9201
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1
57
https://www.td.com/ca/en/personal-banking/solutions/exchange/currency-converter
en
Currency Converter, Foreign Exchange Rates & Services – TD Canada Trust
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Get today's exchange rates, exchange foreign currency cash, transfer funds, send money abroad, and more! Use our currency converter to convert 50+ currencies.
en
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https://www.td.com/ca/en/personal-banking/solutions/exchange/currency-converter
This information is for our Personal Banking Customers. When we refer to foreign currency, we are referring to a currency other than Canadian Dollars. A foreign currency exchange is a purchase that occurs when you purchase foreign currency from us or we purchase foreign currency from you. An exchange rate is the pric...
9201
dbpedia
3
19
http://suffragio.org/2015/07/22/the-lessons-of-newfoundlands-1948-referendum/
en
The lessons of Newfoundland’s 1948 referendum
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[ "" ]
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[ "Kevin Lees" ]
2015-07-22T00:00:00
en
http://suffragio.org/2015/07/22/the-lessons-of-newfoundlands-1948-referendum/
Imagine a North America with three, not two, countries north of the Rio Grande — the United States, Canada and… Newfoundland. Newfoundland!? That’s right. The Canadian outpost in the north Atlantic. Imagine today a proud population of nearly 530,000, now basking in the proceeds of a thriving offshore oil market, growi...
9201
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https://www.wikidata.org/wiki/Q38610
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Dominion of Newfoundland
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UK possession in North America between 1907 and 1949
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UK possession in North America between 1907 and 1949 Newfoundland edit
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https://www.pinterest.com/pin/dominion-of-canada-5-dollars-banknote-1924-queen-mary--853924779320369420/
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2018-03-27T11:37:52+00:00
Dominion of Canada Five Dollar 1924 Queen Mary Dominion of Canada 5 Dollar 1924 Queen Mary Very few of the 1924 $5 notes ever hit ...
en
https://s.pinimg.com/web…144-3da7a67b.png
Pinterest
https://se.pinterest.com/pin/dominion-of-canada-5-dollars-banknote-1924-queen-mary--853924779320369420/
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https://www.amazon.com/1904-1908-Newfoundland-Eventually-Incorporated-Circulated/dp/B0CF7N8HSH
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Amazon.com
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Enter the characters you see below Sorry, we just need to make sure you're not a robot. For best results, please make sure your browser is accepting cookies.
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17
https://globalfinancialdata.com/canada
en
Global Financial Data
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[ "Odin Mayland" ]
0001-11-29T16:07:02-07:52
We are a Global Data provider: For over 25 years Global Financial Data has been providing alternative historical economic and financial data.
en
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https://globalfinancialdata.com/canada
Both the French and British set up colonies in Canada, but in by 1763, the British had gained control over all of New France. Upper and Lower Canada (Ontario and Quebec) were united as the Province of Canada on February 5, 1841, and the Dominion of Canada was established on July 1, 1867. The French Colonial Franc (XFC...
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6
https://britishcurrency.co.uk/newfoundland/
en
Newfoundland – British Currency
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[]
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https://britishcurrency.co.uk/newfoundland/
The dollar was the currency of the colony and, later, Dominion of Newfoundland from 1865 until 1949, when Newfoundland became a province of Canada. It was subdivided into 100 cents. In 1865, coins were introduced in denominations of 1, 5, 10 and 20 cents, and 2 dollars. The 1 cent was struck in bronze, the 5, 10 and 2...
9201
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63
https://www.canada.ca/en/parks-canada/news/2021/06/newfoundland-national-war-memorial-st-johns-newfoundland-and-labrador.html
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Newfoundland National War Memorial, St. John’s, Newfoundland and Labrador
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[ "HI History and Archaeology", "Parks Canada", "Newfoundland and Labrador", "Culture", "history and sport", "general public", "backgrounders", "Hon. Seamus O’Regan" ]
null
[ "Parks Canada" ]
2021-06-28T10:30:00
Unveiled in 1924 to commemorate the Dominion of Newfoundland’s contributions to the First World War, the Newfoundland National War Memorial is an imposing monument and an early example of modern war memorials featuring both allegorical and realistic bronze sculptures.
en
/etc/designs/canada/wet-boew/assets/favicon.ico
https://www.canada.ca/en/parks-canada/news/2021/06/newfoundland-national-war-memorial-st-johns-newfoundland-and-labrador.html
Unveiled in 1924 to commemorate the Dominion of Newfoundland’s contributions to the First World War, the Newfoundland National War Memorial is an imposing monument and an early example of modern war memorials featuring both allegorical and realistic bronze sculptures. Designed by British artists Gilbert Bayes and Ferdi...
9201
dbpedia
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61
https://www.facebook.com/UniforCanada/videos/dominion-workers-in-nl-defend-good-jobs-and-fair-wages-as-negotiations-are-set-t/335547420625515/
en
Dominion workers in NL defend good jobs and fair wages as negotiations are set to begin with parent company Loblaw.
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Dominion workers in NL defend good jobs and fair wages as negotiations are set to begin with parent company Loblaw.
de
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https://www.facebook.com/UniforCanada/videos/dominion-workers-in-nl-defend-good-jobs-and-fair-wages-as-negotiations-are-set-t/335547420625515/
1850
dbpedia
2
7
https://gupea.ub.gu.se/handle/2077/31995
en
Hereditary diffuse leukoencephalopathy with spheroids: Insights into an adult onset neurodegenerative disease
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[]
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[ "" ]
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[]
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en
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null
Abstract During the last three decades, the areas of inherited white matter (WM) disorders have expanded. Advances in magnetic resonance imaging (MRI) and genetics have led to increased detection of adult-onset WM disorders. Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is an adult-onset, invariably let...
1850
dbpedia
3
16
https://www.heartuk.org.uk/genetic-conditions/low-hdl-cholesterol-
en
Low HDL cholesterol
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[ "Low HDL cholesterol", "how to raise HDL cholesterol", "what causes low HDL cholesterol?" ]
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HDL cholesterol is a type of cholesterol that protects your heart health, and it can sometimes fall too low. Read about the causes of low HDL and how you can raise your levels.
en
https://www.heartuk.org.uk/favicon.ico
https://www.heartuk.org.uk/genetic-conditions/low-hdl-cholesterol-
HDL cholesterol is a type of cholesterol that protects your heart health, and it can sometimes fall too low. Why is HDL cholesterol important? What causes low HDL cholesterol? Lower levels of HDL cholesterol can have an underlying cause such as a health problem or certain medications. If you have low HDL cholesterol...
1850
dbpedia
1
19
https://pandsclinic.com/faq-is-high-cholesterol-genetic/
en
FAQ: Is High Cholesterol Genetic?
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[]
[]
[ "" ]
null
[ "Support3" ]
2024-04-10T14:41:39+00:00
High cholesterol is a common health problem that affects millions. A common question is, “Is high cholesterol genetic?”
en
https://pandsclinic.com/…on-Blue-Gray.png
Physicians & Surgeons - OB/GYN, Pediatricians, Internal Medicine
https://pandsclinic.com/faq-is-high-cholesterol-genetic/
High cholesterol is a common but potentially serious health problem that affects millions of people across the country. If you have been diagnosed with high cholesterol, you may be wondering what caused the condition to develop. The truth is that several factors can contribute to high cholesterol levels, which can vary...
1850
dbpedia
0
5
https://medlineplus.gov/genetics/condition/adult-onset-leukoencephalopathy-with-axonal-spheroids-and-pigmented-glia/
en
onset leukoencephalopathy with axonal spheroids and pigmented glia: MedlinePlus Genetics
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[]
[]
[ "" ]
null
[]
null
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a neurological condition characterized by changes to certain areas of the brain. Explore symptoms, inheritance, genetics of this condition.
en
https://medlineplus.gov/images/favicon.ico
https://medlineplus.gov/genetics/condition/adult-onset-leukoencephalopathy-with-axonal-spheroids-and-pigmented-glia/
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a neurological condition characterized by changes to certain areas of the brain. A hallmark of ALSP is leukoencephalopathy, which is the alteration of a type of brain tissue called white matter. White matter consists of nerve fibers (axo...
1850
dbpedia
3
82
https://www.nguyenmed.com/blog/here-are-the-key-differences-between-hdl-and-ldl-cholesterol
en
Here are the Key Differences Between HDL and LDL Cholesterol: Nguyen Medical Group: Internal Medicine
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[]
[]
[ "" ]
null
[]
null
Cholesterol testing helps you keep track of your cholesterol level so you can take steps to manage it. But to really understand your test results, you need to k
en
https://sa1s3optim.patie…/docs/194560.png
https://www.nguyenmed.com/blog/here-are-the-key-differences-between-hdl-and-ldl-cholesterol
About 86 million American adults have high cholesterol, placing them at risk of serious and life-threatening complications like heart disease, heart attack, stroke, and dementia. Even more alarming — only about half of those women and men are currently taking medicine that could help them manage cholesterol and reduce ...
1850
dbpedia
1
74
https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/triglycerides
en
Triglycerides
https://www.betterhealth…mg/bhc-ogimg.png
https://www.betterhealth…mg/bhc-ogimg.png
[ "https://content.dhhs.vic.gov.au/sites/default/files/site_logo/logo.png", "https://content.dhhs.vic.gov.au/sites/default/files/site_logo/dhlogo.png", "https://content.dhhs.vic.gov.au/sites/default/files/site_logo/logo.png", "https://content.dhhs.vic.gov.au/sites/default/files/site_logo/dhlogo.png", "https:/...
[]
[]
[ "alcoholism", "artherosclerosis", "atheroschlerosis", "atherosclerosis", "cholesteral", "cholesterol", "diabetes", "dietary cholesterol", "dietary fat", "dietary fats", "familial hypertriglyceridemia", "fat", "fat content in food", "fats", "fatty plaques", "good fats", "heart desease...
null
[]
2009-06-11T00:00:00
If a person habitually eats more kilojoules than they burn, they will have raised triglyceride levels in the blood.
en
/favicon.ico
http://www.betterhealth.vic.gov.au/health/conditionsandtreatments/triglycerides
Triglycerides are a common type of fat that accounts for about 95 per cent of all dietary fats. Both animal and vegetable fats contain triglycerides. Once digested, triglycerides circulate in the bloodstream to be used as energy by the cells. Any leftovers are stored in body fat to fuel the body between meals. If you ...
1850
dbpedia
0
38
https://europepmc.org/article/med/27338940
en
Europe PMC
https://europepmc.org/images/favicon.ico
https://europepmc.org/images/favicon.ico
[]
[]
[]
[ "Europe PMC", "Europe PubMed Central", "open access", "research articles", "journal articles", "abstracts", "full text", "literature search", "clinical guidelines", "biological patents", "life sciences", "bioinformatics", "biomedical research", "citation search", "biomedical journals", ...
null
[ "Europe PMC" ]
null
Europe PMC is an archive of life sciences journal literature.
en
/images/favicon.ico
null
Europe PMC requires Javascript to function effectively. Either your web browser doesn't support Javascript or it is currently turned off. In the latter case, please turn on Javascript support in your web browser and reload this page.
1850
dbpedia
0
18
https://atm.amegroups.org/article/view/33740/html
en
Clinical features and genetic characteristics of hereditary diffuse leukoencephalopathy with spheroids due to CSF1R mutation: a case report and literature review
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[]
[]
[ "" ]
null
[ "Lv-Ping Zhuang", "Chang-Yun Liu", "Yuan-Xiao Li", "Hua-Ping Huang", "Zhang-Yu Zou" ]
null
Clinical features and genetic characteristics of hereditary diffuse leukoencephalopathy with spheroids due to CSF1R mutation: a case report and literature review
en
//cdn.amegroups.cn/journals/amepc/images/atm/favicon.ico
null
Introduction Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is an autosomal dominant disease that causes adult-onset cognitive impairment, behavioral or emotional changes, paresis, Parkinsonism, and seizures (1). In 1984, Axelsson et al. first reported a family with HDLS (2). In 2011, mutations in the co...
1850
dbpedia
1
0
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275663/
en
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS): a misdiagnosed disease entity
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[]
[]
[ "" ]
null
[ "Christina Sundal", "Jennifer Lash", "Jan Aasly", "Sarka Ø ygarden", "Sigrun Roeber", "Hans Kretzschman", "James Y. Garbern", "Alex Tselis", "Rosa Rademakers", "Dennis W. Dickson" ]
2012-03-15T00:00:00
Hereditary diffuse leukoencephalopathy with spheroids (HDLS) was originally described in a large Swedish pedigree. Since then, 22 reports describing a total of 13 kindred's and 11 sporadic cases have been published. Inheritance is autosomal dominant, ...
en
https://www.ncbi.nlm.nih.gov/coreutils/nwds/img/favicons/favicon.ico
PubMed Central (PMC)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275663/
Introduction Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) was first identified in a Western Swedish family reported in 1984 [1]. There have been 13 kindreds [2–5] and 11 sporadic cases [2, 6–9] since that first report. HDLS is probably closely related to familial pigmentary orthochromatic leukod...
1850
dbpedia
1
15
https://elifesciences.org/reviewed-preprints/96693
en
Modeling Hereditary Diffuse Leukoencephalopathy with Axonal Spheroids using microglia-sufficient brain organoids
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[]
[]
[ "" ]
null
[ "Wei Jie Wong", "Yi Wen Zhu", "Hai Ting Wang", "Jia Wen Qian", "Ziyi Li", "Song Li", "Zhao Yuan Liu", "Wei Guo", "Shuang Yan Zhang", "Bing Su" ]
2024-06-13T00:00:00+00:00
en
null
Introduction Hereditary diffused leukoencephalopathy with axonal spheroids (HDLS) – also known as adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP), is a rare, inherited, autosomal dominant, neurodegenerative disease that is characterized by patchy axonal swellings (spheroids) and demyelinatio...
1850
dbpedia
0
9
https://www.orpha.net/en/disease/detail/313808
en
onset leukoencephalopathy with axonal spheroids and pigmented glia
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[]
null
en
/build/images/favicon.png
null
Knowledge on rare diseases and orphan drugs COVID-19 & Rare diseases Rare Diseases Resources for Refugees/Displaced Persons Homepage > Rare diseases > Search Search for a rare disease * (*) mandatory field Disease name OMIM disease Gene name or symbol ORPHAcode ICD-10 ICD-11 Other search option(s) Alphabet...
1850
dbpedia
3
77
https://ada.com/biomarkers/hdl-cholesterol/
en
HDL cholesterol, known as the “good” cholesterol
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https://ada.com/social-default.png
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[]
[]
[ "" ]
null
[]
2022-09-21T09:22:28+00:00
Want to learn more about HDL cholesterol? In this article, we’ll explain everything you need to know, with handy tips to keep your levels healthy.
en
/favicon-32x32.png
Ada
https://ada.com/biomarkers/hdl-cholesterol/
You probably know that cholesterol levels are an important measure of your health. In particular, lowering cholesterol can keep your heart and blood vessels healthy. So it might surprise you to hear that there's a "good" kind of cholesterol. High-density lipoprotein (HDL) cholesterol is often nicknamed “good cholester...
1850
dbpedia
3
2
https://www.webmd.com/cholesterol-management/hdl-cholesterol-the-good-cholesterol
en
Density Lipoprotein): Overview, Safe Levels
https://img.lb.wbmdstati…erol_bigbead.jpg
https://img.lb.wbmdstati…erol_bigbead.jpg
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[]
[]
[ "" ]
null
[ "Hope Winsborough Matthew Hoffman", "MD Amy Gopal", "www.facebook.com" ]
2008-08-24T20:00:00
HDL (high-density lipoprotein), also known as good cholesterol, reduces the risk of heart diseases. Here's how.
en
https://img.lb.wbmdstati…icon/favicon.png
WebMD
https://www.webmd.com/cholesterol-management/hdl-cholesterol-the-good-cholesterol
What Is HDL Cholesterol? HDL is short for high-density lipoprotein. Each bit of HDL cholesterol is a microscopic blob that consists of a rim of lipoprotein surrounding a cholesterol center. The HDL cholesterol particle is dense compared to other types of cholesterol particles, so it's called high-density. HDL cholest...
1850
dbpedia
1
78
https://my.clevelandclinic.org/health/diseases/23951-tangier-disease
en
Tangier Disease: Symptoms & Treatment
https://my.clevelandclinic.org/-/scassets/images/org/health/articles/social-share-health-library
https://my.clevelandclinic.org/-/scassets/images/org/health/articles/social-share-health-library
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[]
[]
[ "" ]
null
[]
2023-08-28T17:18:10+00:00
Tangier disease is a very rare genetic issue that makes your body have low levels of HDL or “good cholesterol.” This may make you more likely to get heart disease.
en
https://my.clevelandclinic.org/assets/imgs/favicon.ico
Cleveland Clinic
https://my.clevelandclinic.org/health/diseases/23951-tangier-disease
What is Tangier disease? Tangier disease is a rare condition you can get from your parents. People with Tangier disease have very low levels of HDL (high-density lipoprotein). This type of cholesterol is known as “good cholesterol” because it helps get rid of the bad kind of cholesterol (LDL or low-density lipoprotein...
1850
dbpedia
2
95
https://sistershopefoundation.org/about-us/
en
Sisters' Hope Foundation
https://i0.wp.com/sister…it=32%2C32&ssl=1
https://i0.wp.com/sister…it=32%2C32&ssl=1
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[]
[]
[ "" ]
null
[ "heidi3d36319bfd" ]
2023-07-03T08:45:52-07:00
Through Sisters’ Hope Foundation we envision a world where those affected by HDLS/ALSP have support and knowledge, leading to a better quality of life and one
en
https://i0.wp.com/sister…it=32%2C32&ssl=1
Sisters' Hope Foundation
https://sistershopefoundation.org/about-us/
In 2009 we noticed similar personality changes in my Mom. Doctors told us that she had a different disease than her sister, but what became clear was this condition seemed hereditary. There was also no cure and available treatments. Two years after her diagnosis, my Mom passed away of the illness. In the final stages ...
1850
dbpedia
0
35
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2019.00491/full
en
A Novel Splicing Mutation in the CSF1R Gene in a Family With Hereditary Diffuse Leukoencephalopathy With Axonal Spheroids
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[]
[]
[ "Hereditary diffuse leukoencephalopathy with axonal spheroids", "Csf1r", "Neuroimages", "Whole-exome sequencing", "splicing mutation" ]
null
[]
null
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) is a rare autosomal dominant disorder that typically presents with early-onset cognitive ...
en
https://brand.frontiersi…on-Frontiers.png
Frontiers
https://www.frontiersin.org/journals/genetics/articles/10.3389/fgene.2019.00491/full
Introduction Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) is a rare autosomal dominant disorder characterized by cerebral white matter degeneration and corpus callosum atrophy (Axelsson et al., 1984). It is clinically characterized by adult-onset neuropsychiatric symptoms, progressive cognitive ...
1850
dbpedia
3
3
https://www.healthline.com/health/high-hdl
en
High HDL Cholesterol: Can It Be a Problem?
https://media.post.rvohe…_Be_Too_High.jpg
https://media.post.rvohe…_Be_Too_High.jpg
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[]
[]
[ "high hdl" ]
null
[ "Kristeen Cherney" ]
2017-03-27T07:00:00+00:00
Doctors usually recommend having high levels of HDL cholesterol, but in some rare cases HDL levels can be too high. Learn more.
en
https://images-prod.heal…e-touch-icon.png
Healthline
https://www.healthline.com/health/high-hdl
Research published by the journal Arteriosclerosis, Thrombosis, and Vascular Biology found that people with high levels of C-reactive proteins after having had a heart attack may process high HDL negatively. C-reactive proteins are produced by your liver in response to high levels of inflammation in your body. Instead ...
1850
dbpedia
1
80
https://www.massgeneral.org/news/press-release/genetic-testing-for-a-lipoprotein-linked-to-cardiovascular-risk-is-as-effective-as-blood-work
en
Genetic testing for a lipoprotein linked to cardiovascular risk is as effective as blood work, study shows
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[]
[]
[ "" ]
null
[ "Julie Cunningham" ]
null
en
/assets/MGH/images/favicon/apple-touch-icon.png
Massachusetts General Hospital
https://www.massgeneral.org/news/press-release/genetic-testing-for-a-lipoprotein-linked-to-cardiovascular-risk-is-as-effective-as-blood-work
BOSTON – Elevated levels of a little-known lipoprotein in the blood that may put people at high risk of cardiovascular disease can be as accurately detected by genetic testing as by conventional laboratory measurement, researchers at Massachusetts General Hospital (MGH) have found. In a study published in JAMA Cardiolo...
1850
dbpedia
0
23
https://alextlc.org/condition/alsp-csf1r-related-leukoencephalopathy/
en
Adult onset leukoencephalopathy with axonal spheroids and pigmented glia/CSF1R related leukoencephalopathy
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[]
[]
[ "" ]
null
[]
2023-07-19T11:19:56+00:00
Description of the condition CSF1R related leukoencephalopathy is caused by mutations in the CSF1R gene. People usually begin experiencing symptoms in their 40’s-60’s although this may vary, even within families. Symptoms can be subtle in early stages, and many patients will first present to memory clinics, psychiatry ...
en
https://alextlc.org/wp-c…2022/09/icon.svg
Alex - The Leukodystrophy Charity
https://alextlc.org/condition/alsp-csf1r-related-leukoencephalopathy/
Inheritance Autosomal dominant: In autosomal dominant conditions, only one copy of the genetic mutation is needed to cause the condition. We all have two copies of every gene, one from our mother and one from our father. Someone with an autosomal dominant condition has one parent with a copy of the genetic mutation an...
1850
dbpedia
1
38
https://www.cdc.gov/heart-disease-family-history/about/about-lipoprotein-a.html
en
About Lipoprotein (a)
https://www.cdc.gov/hear…tein.jpg?_=98752
https://www.cdc.gov/hear…tein.jpg?_=98752
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[]
[]
[ "" ]
null
[]
2024-05-17T08:34:59-04:00
High levels of lipoprotein (a) increase the risk of heart attack, stroke, and aortic stenosis.
en
/TemplatePackage/5.0/img/favicon/apple-touch-icon.png
Heart Disease, Family Health History, and Familial Hypercholesterolemia
https://www.cdc.gov/heart-disease-family-history/about/about-lipoprotein-a.html
What it is High levels of lipoprotein (a) (Lp(a), pronounced “L-P-little-A”) increase your likelihood of having a heart attack, a stroke, and aortic stenosis, especially if you have familial hypercholesterolemia (FH) or signs of coronary heart disease. Cholesterol travels through the blood on lipoproteins, which are m...
1850
dbpedia
0
8
https://www.huntershope.org/hdls/
en
ALSP
https://huntershope.wpen…00x300-45x45.jpg
https://huntershope.wpen…00x300-45x45.jpg
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[]
[]
[ "" ]
null
[]
null
en
https://huntershope.wpen…00x300-45x45.jpg
https://www.huntershope.org/hdls/
What is ALSP or Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia? ALSP is a rare adult onset autosomal dominant disorder characterized by changes to certain parts of the brain. As the disorder name indicates, the individual will experience leukoencephalopathy, which is damage to the white matte...
1850
dbpedia
1
14
https://www.webmd.com/cholesterol-management/hdl-cholesterol-the-good-cholesterol
en
Density Lipoprotein): Overview, Safe Levels
https://img.lb.wbmdstati…erol_bigbead.jpg
https://img.lb.wbmdstati…erol_bigbead.jpg
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[ "" ]
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[ "Hope Winsborough Matthew Hoffman", "MD Amy Gopal", "www.facebook.com" ]
2008-08-24T20:00:00
HDL (high-density lipoprotein), also known as good cholesterol, reduces the risk of heart diseases. Here's how.
en
https://img.lb.wbmdstati…icon/favicon.png
WebMD
https://www.webmd.com/cholesterol-management/hdl-cholesterol-the-good-cholesterol
What Is HDL Cholesterol? HDL is short for high-density lipoprotein. Each bit of HDL cholesterol is a microscopic blob that consists of a rim of lipoprotein surrounding a cholesterol center. The HDL cholesterol particle is dense compared to other types of cholesterol particles, so it's called high-density. HDL cholest...
1850
dbpedia
1
1
https://medlineplus.gov/genetics/condition/familial-hdl-deficiency/
en
Familial HDL deficiency: MedlinePlus Genetics
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[ "" ]
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[]
null
Familial HDL deficiency is a condition characterized by low levels of high-density lipoprotei% (HDL) in the blood. Explore symptoms, inheritance, genetics of this condition.
en
https://medlineplus.gov/images/favicon.ico
https://medlineplus.gov/genetics/condition/familial-hdl-deficiency/
Familial HDL deficiency is a condition characterized by low levels of high-density lipoprotei% (HDL) in the blood. HDL is a molecule that transports cholesterol and certain fats called phospholipids through the bloodstream from the body's tissues to the liver. Once in the liver, cholesterol and phospholipids are redist...
1850
dbpedia
0
19
https://mayoclinic.elsevierpure.com/en/publications/leukoencephalopathy-with-spheroids-hdls-and-pigmentary-leukodystr
en
Leukoencephalopathy with spheroids (HDLS) and pigmentary leukodystrophy (POLD): A single entity?
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[ "" ]
null
[ "C. Wider", "J. A. Van Gerpen", "S. Dearmond", "E. A. Shuster", "D. W. Dickson", "Z. K. Wszolek" ]
null
en
Mayo Clinic
https://mayoclinic.elsevierpure.com/en/publications/leukoencephalopathy-with-spheroids-hdls-and-pigmentary-leukodystr
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) and familial pigmentary orthochromatic leukodystrophy (POLD) present as adult-onset dementia with motor impairment and epilepsy. They are regarded as distinct diseases. We review data from the literature that support their being a single entity. Apart ...
1850
dbpedia
2
77
https://en.wikipedia.org/wiki/3D_cell_culture
en
3D cell culture
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[]
[]
[ "" ]
null
[ "Contributors to Wikimedia projects" ]
2013-07-08T21:36:28+00:00
en
/static/apple-touch/wikipedia.png
https://en.wikipedia.org/wiki/3D_cell_culture
Free-floating three-dimensional culture of cells A 3D cell culture is an artificially created environment in which biological cells are permitted to grow or interact with their surroundings in all three dimensions. Unlike 2D environments (e.g. a Petri dish), a 3D cell culture allows cells in vitro to grow in all direc...
1850
dbpedia
2
61
https://search.lib.utexas.edu/discovery/fulldisplay%3Fdocid%3Dcdi_proquest_miscellaneous_2542364371%26context%3DPC%26vid%3D01UTAU_INST:SEARCH%26lang%3Den%26search_scope%3DMyInst_and_CI%26adaptor%3DPrimo%2520Central%26tab%3DEverything%26query%3Dcreator%252Cexact%252C%2520Ikegawa%252C%2520Shiro%2520%252CAND%26mode%3Dadva...
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[]
[]
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[ "" ]
null
[]
null
en
null
1850
dbpedia
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4
https://journals.lww.com/md-journal/fulltext/2019/05310/diagnosis_of_hereditary_diffuse.40.aspx
en
Medicine
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[ "" ]
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null
erogeneities; also, it is classed as a neurodegenerative disease. Patient concerns: In preliminary clinical work, we identified a family with rapid progressive dementia. Diagnosis: Within this family, all patients had a CSF1R gene c.2696delA mutation (a deletion mutation), and head magnetic resonance imaging ...
en
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LWW
https://journals.lww.com/md-journal/fulltext/2019/05310/diagnosis_of_hereditary_diffuse.40.aspx
1 Introduction Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is a rare disease involving white matter lesions of the central nervous system, and it is usually inherited in an autosomal dominant fashion. It is a neurodegenerative disease with obvious clinical and genetic heterogeneities, and ...
1850
dbpedia
1
6
https://en.wikipedia.org/wiki/Hereditary_diffuse_leukoencephalopathy_with_spheroids
en
Hereditary diffuse leukoencephalopathy with spheroids
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[]
[ "" ]
null
[ "Contributors to Wikimedia projects" ]
2011-12-30T22:14:56+00:00
en
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https://en.wikipedia.org/wiki/Hereditary_diffuse_leukoencephalopathy_with_spheroids
Medical condition Hereditary diffuse leukoencephalopathy with spheroids (HDLS)Other namesAdult-onset leukoencephalopathy with axonal spheroids and pigmented glia, Autosomal dominant leukoencephalopathy with neuroaxonal spheroidsHereditary diffuse leukoencephalopathy with spheroids is inherited in an autosomal dominant...
1850
dbpedia
1
13
https://www.healthpartners.com/blog/is-high-cholesterol-hereditary/
en
Is high cholesterol hereditary? What you need to know
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[]
[]
[]
[ "" ]
null
[ "Kaitlyn Votel", "HealthPartners" ]
2024-07-05T15:02:52+00:00
Familial hypercholesterolemia is a genetic disorder that causes high cholesterol. Learn about the risk factors and treatments for hereditary high cholesterol.
en
https://www.healthpartners.com/content/dam/brand-identity/icons/hp-favicon.ico
HealthPartners Blog
https://www.healthpartners.com/blog/is-high-cholesterol-hereditary/
Cholesterol is a waxy, fat-like substance in your blood stream that helps with digesting fatty foods and making hormones. It’s essential for good health. However, having too much cholesterol can cause heart disease, strokes and other health issues. High cholesterol is a common condition that affects about 2 out of 5 A...
1850
dbpedia
2
85
https://encyclopedia.pub/video/video_detail/342
en
The Lipid Energy Model
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Encyclopedia is a user-generated content hub aiming to provide a comprehensive record for scientific developments. All content free to post, read, share and reuse.
en
/favicon.ico
https://encyclopedia.pub/video/video_detail/342
When lean people adopt carbohydrate-restricted diets (CRDs), they may develop a lipid profile consisting of elevated LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) with low triglycerides (TGs). The magnitude of this lipid profile correlates with BMI such that those with lower BMI exhibit larger increases in both L...
1850
dbpedia
0
24
https://mayoclinic.elsevierpure.com/en/publications/hereditary-diffuse-leukoencephalopathy-with-axonal-spheroids-hdls
en
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS): A misdiagnosed disease entity
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[]
[]
[ "" ]
null
[ "Christina Sundal", "Jennifer Lash", "Jan Aasly", "Sarka Øygarden", "Sigrun Roeber", "Hans Kretzschman", "James Y. Garbern", "Alex Tselis", "Rosa Rademakers", "Dennis W. Dickson" ]
null
en
Mayo Clinic
https://mayoclinic.elsevierpure.com/en/publications/hereditary-diffuse-leukoencephalopathy-with-axonal-spheroids-hdls
Hereditary diffuse leukoencephalopathy with spheroids (HDLS) was originally described in a large Swedish pedigree. Since then, 22 reports describing a total of 13 kindreds and 11 sporadic cases have been published. Inheritance is autosomal dominant, albeit the gene is unknown. Here we report on the clinical findings, g...
1850
dbpedia
3
4
https://www.heart.org/en/health-topics/cholesterol/hdl-good-ldl-bad-cholesterol-and-triglycerides
en
HDL (Good), LDL (Bad) Cholesterol and Triglycerides
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[]
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[ "" ]
null
[]
2018-01-11T00:00:00
Two types of lipoproteins carry cholesterol to and from cells. One is low-density lipoprotein, or LDL. The other is high-density lipoprotein, or HDL. A test measures the amount of each type of cholesterol in your blood.
en
/favicon.ico
www.heart.org
https://www.heart.org/en/health-topics/cholesterol/hdl-good-ldl-bad-cholesterol-and-triglycerides
Cholesterol: The good and the bad Two types of lipoproteins carry cholesterol to and from cells. One is low-density lipoprotein, or LDL. The other is high-density lipoprotein, or HDL. A test measures the amount of each type of cholesterol in your blood. LDL cholesterol LDL cholesterol is considered the “bad” cholest...
1850
dbpedia
3
67
https://www.modernheartandvascular.com/difference-between-ldl-and-hdl-cholesterol/
en
The Difference Between LDL and HDL Cholesterol
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[ "" ]
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[ "Growth360Partners" ]
2022-04-13T17:44:37+00:00
There are two main types of cholesterol, including high-density lipoprotein and low-density lipoprotein. Learn the difference between LDL and HDL cholesterol.
en
https://cdn-ilbdkgn.nitr…icon-150x150.png
Modern Heart and Vascular
https://www.modernheartandvascular.com/difference-between-ldl-and-hdl-cholesterol/
Cholesterol is a waxy substance found in the blood, created by the liver and the foods you eat. Two lipoproteins carry your cholesterol, including low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL is commonly referred to as bad cholesterol. LDL comprises the larger portion of your overall cholestero...
1850
dbpedia
1
91
https://www.orpha.net/en/disease/detail/313808
en
onset leukoencephalopathy with axonal spheroids and pigmented glia
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en
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null
Knowledge on rare diseases and orphan drugs COVID-19 & Rare diseases Rare Diseases Resources for Refugees/Displaced Persons Homepage > Rare diseases > Search Search for a rare disease * (*) mandatory field Disease name OMIM disease Gene name or symbol ORPHAcode ICD-10 ICD-11 Other search option(s) Alphabet...
1850
dbpedia
2
1
https://jnnp.bmj.com/content/87/5/512
en
Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series
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[]
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[ "" ]
null
[ "David S Lynch", "Zane Jaunmuktane", "Una-Marie Sheerin", "Rahul Phadke", "Sebastian Brandner", "Ionnis Milonas", "Andrew Dean", "Nin Bajaj", "Nuala McNicholas", "Daniel Costello" ]
2016-05-01T00:00:00
Background Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is a hereditary, adult onset leukodystrophy which is characterised by the presence of axonal loss, axonal spheroids and variably present pigmented macrophages on pathological examination. It most frequently presents in adulthood with de...
en
https://jnnp.bmj.com/sites/default/themes/bmjj/favicon.ico
Journal of Neurology, Neurosurgery & Psychiatry
https://jnnp.bmj.com/content/87/5/512
Introduction Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is an autosomal dominant, adult onset leukodystrophy which typically presents with early onset cognitive or personality change. It is characterised by a distinct neuropathological appearance consisting of axonal loss in the cerebral ...
1850
dbpedia
3
47
https://www.upmc.com/services/heart-vascular/conditions-treatments/hypercholesterolemia
en
Hypercholesterolemia Symptoms and Treatment
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https://dam.upmc.com/-/m…88131a9c2748fa9c
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Learn more about the symptoms, diagnosis, and treatment of hypercholesterolemia at the UPMC Heart and Vascular Institute, located in Pittsburgh.
en
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UPMC | Life Changing Medicine
https://www.upmc.com/services/heart-vascular/conditions-treatments/hypercholesterolemia
What Is Hypercholesterolemia? Hypercholesterolemia is the medical term for high cholesterol. Your body needs some cholesterol to make hormones and digest fatty foods. But too much raises the risk of heart disease and other cardiovascular problems. About 38% of American adults have high cholesterol. There are two ma...
1850
dbpedia
0
53
https://www.academia.edu/93052364/Parkinsonian_features_in_hereditary_diffuse_leukoencephalopathy_with_spheroids_HDLS_and_CSF1R_mutations
en
Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations
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[ "" ]
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[ "Dennis Dickson", "independent.academia.edu" ]
2022-12-16T00:00:00
Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations
https://www.academia.edu/93052364/Parkinsonian_features_in_hereditary_diffuse_leukoencephalopathy_with_spheroids_HDLS_and_CSF1R_mutations
Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is a hereditary, adult onset leukodystrophy which is characterised by the presence of axonal loss, axonal spheroids and variably present pigmented macrophages on pathological examination. It most frequently presents in adulthood with dementia and ...
1850
dbpedia
1
48
https://www.genome.gov/Genetic-Disorders/Familial-Hypercholesterolemia
en
About Familial Hypercholesterolemia
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[]
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[ "" ]
null
[ "NHGRI" ]
2019-03-09T00:13:30-05:00
Familial hypercholesterolemia is an inherited condition causing increased low density lipoprotein cholesterol at birth and heart attacks at an early age.
en
/themes/custom/nhgri/favicon.ico
Genome.gov
https://www.genome.gov/Genetic-Disorders/Familial-Hypercholesterolemia
Familial hypercholesterolemia is an inherited condition that causes high levels of LDL (low density lipoprotein) cholesterol beginning at birth, and heart attacks at an early age. Cholesterol is a fat-like substance that is found in the cells of the body. Cholesterol is also found in some foods. The body needs some cho...
1850
dbpedia
0
3
https://jnnp.bmj.com/content/87/5/512
en
Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series
https://jnnp.bmj.com/sit…cover-source.jpg
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[]
[]
[ "" ]
null
[ "David S Lynch", "Zane Jaunmuktane", "Una-Marie Sheerin", "Rahul Phadke", "Sebastian Brandner", "Ionnis Milonas", "Andrew Dean", "Nin Bajaj", "Nuala McNicholas", "Daniel Costello" ]
2016-05-01T00:00:00
Background Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is a hereditary, adult onset leukodystrophy which is characterised by the presence of axonal loss, axonal spheroids and variably present pigmented macrophages on pathological examination. It most frequently presents in adulthood with de...
en
https://jnnp.bmj.com/sites/default/themes/bmjj/favicon.ico
Journal of Neurology, Neurosurgery & Psychiatry
https://jnnp.bmj.com/content/87/5/512
Introduction Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is an autosomal dominant, adult onset leukodystrophy which typically presents with early onset cognitive or personality change. It is characterised by a distinct neuropathological appearance consisting of axonal loss in the cerebral ...
1850
dbpedia
2
89
https://uis.brage.unit.no/uis-xmlui/handle/11250/2999548%3Flocale-attribute%3Dno
en
UiS Brage: Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines
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[ "Hanne Røland", "Tia R", "Gro Vatne", "Karl Johan" ]
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https://www.webmd.com/cholesterol-management/good-cholesterol-too-high
en
Can High Levels of Good Cholesterol Be Bad for You?
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[ "" ]
null
[ "Stephanie Watson", "www.facebook.com" ]
2021-06-14T08:00:00
Experts tell us to boost our HDL level, but very high levels of this "good" type of cholesterol could increase heart disease risk.
en
https://img.lb.wbmdstati…icon/favicon.png
WebMD
https://www.webmd.com/cholesterol-management/good-cholesterol-too-high
What Is Good Cholesterol? There are two types of cholesterol, the waxy substance found in your blood. Low-density lipoprotein (LDL) cholesterol is considered "bad" cholesterol because it can build up inside your arteries and lead to heart attacks and strokes. The high-density lipoprotein (HDL) type is often called "go...
1850
dbpedia
1
72
https://www.nytimes.com/2012/05/17/health/research/hdl-good-cholesterol-found-not-to-cut-heart-risk.html
en
HDL ‘Good Cholesterol’ Found Not to Cut Heart Risk
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https://static01.nyt.com…op.png?year=2012
[]
[]
[]
[ "" ]
null
[ "Gina Kolata" ]
2012-05-17T00:00:00
People genetically prone to higher levels of HDL, often called “good cholesterol,” showed that they did not have any significant decrease in risk of cardiovascular disease.
en
/vi-assets/static-assets/favicon-d2483f10ef688e6f89e23806b9700298.ico
https://www.nytimes.com/2012/05/17/health/research/hdl-good-cholesterol-found-not-to-cut-heart-risk.html
The name alone sounds so encouraging: HDL, the “good cholesterol.” The more of it in your blood, the lower your risk of heart disease. So bringing up HDL levels has got to be good for health. Or so the theory went. Now, a new study that makes use of powerful databases of genetic information has found that raising HDL...
1850
dbpedia
1
25
https://www.everydayhealth.com/high-cholesterol/treatment/10-things-you-need-to-know-about-inherited-high-cholesterol/
en
9 Things You Need to Know About Inherited High Cholesterol
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[]
[ "" ]
null
[ "Zachary Smith", "Anurag Sahu" ]
2024-08-01T00:00:00
For some, high cholesterol runs in the family — which many won’t know if they don’t have symptoms. Here is everything you need to know about who is at risk, what the signs are, and how to treat inherited high cholesterol, also known as familial hypercholesterolemia or FH.
en
//images.everydayhealth.com/images/site-images/favicon.png
EverydayHealth.com
https://www.everydayhealth.com/high-cholesterol/treatment/10-things-you-need-to-know-about-inherited-high-cholesterol/
FH Plays a Trick on the Liver FH is caused by faulty LDL receptors that can’t cycle cholesterol from the bloodstream through the liver. But that’s only part of the problem. FH convinces the liver that the body isn’t getting any cholesterol, which forces the liver to manufacture more of its own cholesterol and signals...
1850
dbpedia
2
71
https://researchportal.lih.lu/en/publications/comprehensive-diagnostics-in-a-case-of-hereditary-diffuse-leukody
en
Comprehensive diagnostics in a case of hereditary diffuse leukodystrophy with spheroids
https://researchportal.lih.lu/skin/headerImage/
https://researchportal.lih.lu/skin/headerImage/
[ "https://researchportal.lih.lu/skin/headerImage/" ]
[]
[]
[ "" ]
null
[ "Marie Meyer-Ohlendorf", "Anne Braczynski", "Omar Al-Qaisi", "Florian Gessler", "Saskia Biskup", "Lutz Weise", "Joachim P. Steinbach", "Marlies Wagner", "Michel Mittelbronn", "Oliver Bähr" ]
null
en
Luxembourg Institute of Health
https://researchportal.lih.lu/en/publications/comprehensive-diagnostics-in-a-case-of-hereditary-diffuse-leukody
Background: Hereditary diffuse leukodystrophy with spheroids is a rare type of leukoencephalopathy. Mutations in the colony stimulating factor 1 receptor have recently been identified to be the cause of this microgliopathy. Clinical and radiological presentation can often misguide physicians during the diagnosis of pat...
1850
dbpedia
1
73
https://www.nhs.uk/conditions/high-cholesterol/
en
High cholesterol
https://www.nhs.uk/stati…a74435697f45.png
https://www.nhs.uk/stati…a74435697f45.png
[]
[]
[]
[ "" ]
null
[ "NHS website", "www.facebook.com" ]
2017-10-23T10:47:00
Find out what cholesterol is, what causes high cholesterol, why it's important to keep your cholesterol levels under control, and how to lower your cholesterol.
en
/static/nhsuk/img/favicons/favicon.68c7f017cfba.ico
nhs.uk
https://www.nhs.uk/conditions/high-cholesterol/
What is high cholesterol? High cholesterol is when you have too much of a fatty substance called cholesterol in your blood. It's mainly caused by eating fatty food, not exercising enough, being overweight, smoking and drinking alcohol. It can also run in families. You can lower your cholesterol by eating healthily a...
1850
dbpedia
2
67
https://biblio.ugent.be/publication/01HS18P75V7B4P8F8J4D8QVE5H
en
Chronic exposure to dietary compounds shifts bioenergetics in colorectal cancer
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[]
[]
[ "" ]
null
[ "Elien Alderweireldt ( UGent )", "Charlotte Grootaert ( UGent )", "Andreja Rajkovic ( UGent )", "Filip Van Nieuwerburgh ( UGent )", "John Van Camp ( UGent )", "Van Nieuwerburgh", "Van Camp", "De Wever" ]
2023-08-19T00:00:00
nl
/favicon.ico
https://biblio.ugent.be/publication/01HS18P75V7B4P8F8J4D8QVE5H
@inproceedings{01HS18P75V7B4P8F8J4D8QVE5H, abstract = {{Nutritional availability in the colonic microenvironment, influenced by dietary habits and further diversified by gut microorganisms, affects the energetic options of colorectal cancer (CRC) cells. Moreover, specific compounds may alter their metabolic flexibility...
1850
dbpedia
0
2
https://ulf.org/leukodystrophies/hereditary-diffuse-leukoencephalopathy-with-spheroids-hdls/
en
Hereditary Diffuse Leukoencephalopathy with Spheroids (HDLS)
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[]
[]
[ "" ]
null
[]
2020-04-10T20:16:09+00:00
Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is an autosomal dominant progressive disease.
en
https://0zv8e8.a2cdn1.secureserver.net/wp-content/uploads/2019/12/favicon.ico?time=1723756663
United Leukodystrophy Foundation
https://ulf.org/leukodystrophies/hereditary-diffuse-leukoencephalopathy-with-spheroids-hdls/
causes of Neuroaxonal leukoencephalopathy with axonal spheriods Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is an autosomal dominant progressive disease. The disease was described for the first time in multiple members of a large Swedish pedigree in 1984 (Axelsson et al, 1984). In this family, 17 of 7...
1850
dbpedia
1
49
https://www.hopkinsmedicine.org/health/conditions-and-diseases/high-cholesterol/what-to-do-when-high-cholesterol-runs-in-your-family
en
What to Do When High Cholesterol Runs in Your Family
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[]
[]
[ "" ]
null
[]
2021-11-11T00:00:00
Because high cholesterol doesn’t have any symptoms, it’s not something that’s commonly on people’s radar.
en
/favicon.ico
https://www.hopkinsmedicine.org/health/conditions-and-diseases/high-cholesterol/what-to-do-when-high-cholesterol-runs-in-your-family
Featured Expert:
1850
dbpedia
0
52
https://researchportal.lih.lu/en/publications/de-novo-mutations-in-hereditary-diffuse-leukoencephalopathy-with-
en
De novo mutations in hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS)
https://researchportal.lih.lu/skin/headerImage/
https://researchportal.lih.lu/skin/headerImage/
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[]
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[ "" ]
null
[ "Kathrin N. Karle", "Saskia Biskup", "Rebecca Schüle", "Katherine J. Schweitzer", "Rejko Krüger", "Peter Bauer", "Benjamin Bender", "Thomas Nägele", "Ludger Schöls" ]
null
en
Luxembourg Institute of Health
https://researchportal.lih.lu/en/publications/de-novo-mutations-in-hereditary-diffuse-leukoencephalopathy-with-
Objective: Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) is caused by autosomal-dominantly inherited mutations in the colony stimulating factor 1 receptor (CSF1R) gene, and is clinically characterized by a progressive cognitive and motor decline leading to death within several years. Methods: In a...
1850
dbpedia
3
11
https://medlineplus.gov/genetics/condition/familial-hdl-deficiency/
en
Familial HDL deficiency: MedlinePlus Genetics
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https://medlineplus.gov/…dition_Share.jpg
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[]
[]
[ "" ]
null
[]
null
Familial HDL deficiency is a condition characterized by low levels of high-density lipoprotei% (HDL) in the blood. Explore symptoms, inheritance, genetics of this condition.
en
https://medlineplus.gov/images/favicon.ico
https://medlineplus.gov/genetics/condition/familial-hdl-deficiency/
Familial HDL deficiency is a condition characterized by low levels of high-density lipoprotei% (HDL) in the blood. HDL is a molecule that transports cholesterol and certain fats called phospholipids through the bloodstream from the body's tissues to the liver. Once in the liver, cholesterol and phospholipids are redist...
1850
dbpedia
2
0
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995741/
en
Clinical features and genetic characteristics of hereditary diffuse leukoencephalopathy with spheroids due to CSF1R mutation: a case report and literature review
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[]
[]
[ "" ]
null
[ "Lv-Ping Zhuang", "Chang-Yun Liu", "Yuan-Xiao Li", "Hua-Ping Huang", "Zhang-Yu Zou" ]
2020-01-19T00:00:00
Hereditary diffuse leukoencephalopathy with spheroid (HDLS) is an autosomal dominant white matter disease characterized by adult-onset cognitive impairment, behavioral or emotional changes, paresis, Parkinsonism, and seizures. Mutations in the gene encoding ...
en
https://www.ncbi.nlm.nih.gov/coreutils/nwds/img/favicons/favicon.ico
PubMed Central (PMC)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995741/
Discussion In this study, we identified a novel missense mutation p.G651E in the CSF1R gene in a patient presenting with adult-onset leukoencephalopathy, cognitive impairment and motor dysfunction. G651 is highly conserved across species ( ) and lies in the TKD domain, the critical domain of CSF1R (PM1). The p.G651H v...
1850
dbpedia
3
46
https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/genetic-factors-and-cholesterol
en
Genetic factors and cholesterol
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[]
[]
[ "angina", "chest pain", "cholesterol", "cholesterol-lowering drugs", "genetic condition", "genetic counselling", "heart attacks young", "high blood cholesterol", "high LDL", "inherited conditions", "plant sterols", "plant stanols" ]
null
[]
2003-01-28T00:00:00
Familial hypercholesterolaemia is an inherited condition characterised by higher than normal levels of blood cholesterol.
en
/favicon.ico
http://www.betterhealth.vic.gov.au/health/conditionsandtreatments/genetic-factors-and-cholesterol
Cholesterol is an essential component of cell membranes and is needed for many bodily functions, such as the production of hormones. It is produced when foods containing oil and fat are digested. It is also produced in the liver. Cholesterol in the blood is found in two types of particles. The cholesterol in low densi...
1850
dbpedia
3
66
https://health.gov/myhealthfinder/doctor-visits/screening-tests/get-your-cholesterol-checked
en
Get Your Cholesterol Checked - MyHealthfinder
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[]
[]
[ "" ]
null
[]
2022-05-01T12:00:00+00:00
Too much cholesterol in your blood can cause a heart attack or a stroke. Share this resource to encourage people age 40 to 75 to get their cholesterol checked regularly.
en
/themes/custom/healthfinder/images/favicon.png
https://health.gov/myhealthfinder/doctor-visits/screening-tests/get-your-cholesterol-checked
It's important to get your cholesterol checked regularly. Too much cholesterol in your blood can cause a heart attack or a stroke. The good news is that it’s easy to get your cholesterol checked. If your cholesterol is high, you can take steps to lower it — like eating healthy, getting more physical activity, and taki...
1850
dbpedia
0
33
https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-019-0843-y
en
An AARS variant as the likely cause of Swedish type hereditary diffuse leukoencephalopathy with spheroids
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[]
[]
[ "" ]
null
[ "Hedberg-Oldfors" ]
2019-11-27T00:00:00
Swedish type Hereditary Diffuse Leukoencephalopathy with Spheroids (HDLS-S) is a severe adult-onset leukoencephalopathy with the histopathological hallmark of neuraxonal degeneration with spheroids, described in a large family with a dominant inheritance pattern. The initial stage of the disease is dominated by frontal...
en
/static/img/favicons/bmc/apple-touch-icon-582ef1d0f5.png
BioMed Central
https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-019-0843-y
All samples included in this study were collected from one large Swedish family originally described in 1984 [4]. The updated family tree is presented in Fig. 1 with four generations represented and including information from the most recent clinical assessments. DNA was extracted using QIAsymphony, following standard ...
1850
dbpedia
1
86
https://mayoclinic.elsevierpure.com/en/publications/leukoencephalopathy-with-spheroids-hdls-and-pigmentary-leukodystr
en
Leukoencephalopathy with spheroids (HDLS) and pigmentary leukodystrophy (POLD): A single entity?
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https://mayoclinic.elsevierpure.com/skin/headerImage/
[ "https://mayoclinic.elsevierpure.com/skin/headerImage/" ]
[]
[]
[ "" ]
null
[ "C. Wider", "J. A. Van Gerpen", "S. Dearmond", "E. A. Shuster", "D. W. Dickson", "Z. K. Wszolek" ]
null
en
Mayo Clinic
https://mayoclinic.elsevierpure.com/en/publications/leukoencephalopathy-with-spheroids-hdls-and-pigmentary-leukodystr
Hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS) and familial pigmentary orthochromatic leukodystrophy (POLD) present as adult-onset dementia with motor impairment and epilepsy. They are regarded as distinct diseases. We review data from the literature that support their being a single entity. Apart ...
1850
dbpedia
3
5
https://www.cdc.gov/cholesterol/about/ldl-and-hdl-cholesterol-and-triglycerides.html
en
LDL and HDL Cholesterol and Triglycerides
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https://www.cdc.gov/chol…cial.jpg?_=98669
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[]
[]
[ "" ]
null
[]
2024-05-20T12:25:16-04:00
Learn about the lipoproteins that carry cholesterol in the blood, called LDL and HDL, and what triglycerides are.
en
/TemplatePackage/5.0/img/favicon/apple-touch-icon.png
Cholesterol
https://www.cdc.gov/cholesterol/about/ldl-and-hdl-cholesterol-and-triglycerides.html
What are triglycerides? Triglycerides are a type of fat in your blood that your body uses for energy. The combination of high levels of triglycerides with low HDL and/or high LDL cholesterol levels can increase your risk for health problems, such as heart attack. Learn more about optimal blood cholesterol and trigly...
1850
dbpedia
3
70
https://familydoctor.org/condition/cholesterol/
en
High Cholesterol: Symptoms, Causes and Treatment
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[]
[]
[ "" ]
null
[ "familydoctor.org editorial staff" ]
1996-01-01T05:00:00+00:00
High cholesterol is a medical condition that can lead to stroke and heart disease. Many people are unaware they have high cholesterol.
en
https://familydoctor.org…/favicon16-1.png
familydoctor.org
https://familydoctor.org/condition/cholesterol/
Cholesterol is a waxy substance your liver makes to protect nerves and to make cell tissue and certain hormones. Your body also gets cholesterol from the food you eat. This includes eggs, meats, and dairy. There is “good” (HDL) cholesterol and “bad” (LDL) cholesterol. Too much bad cholesterol (LDL) can be bad for your ...
1850
dbpedia
1
69
https://leukodystrophyresourceresearch.org/types-of-leukodystrophy/neuroaxonal-leukoencephalopathy-with-axonal-spheroids-hereditary-diffuse-leukoencephalopathy-with-spheroids-hdls/
en
Neuroaxonal Leukoencephalopathy with Axonal Spheroids (Hereditary Diffuse Leukoencephalopathy with Spheroids – HDLS)
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[]
[]
[ "" ]
null
[]
null
en
/wp-content/uploads/2018/07/cropped-12299-6-32x32.jpg
https://leukodystrophyresourceresearch.org/types-of-leukodystrophy/neuroaxonal-leukoencephalopathy-with-axonal-spheroids-hereditary-diffuse-leukoencephalopathy-with-spheroids-hdls/
What Causes Neuroaxonal Leukoencephalopathy with Axonal Spheroids Hereditary diffuse leukoencephalopathy with spheroids (HDLS) is an autosomal dominant progressive disease. The disease was described for the first time in multiple members of a large Swedish pedigree in 1984 (Axelsson et al, 1984). In this family, 17 of...
1850
dbpedia
1
7
https://journals.lww.com/md-journal/fulltext/2019/05310/diagnosis_of_hereditary_diffuse.40.aspx
en
Medicine
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https://images.journals.…10-00040.F1.jpeg
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[]
[]
[ "" ]
null
[]
null
erogeneities; also, it is classed as a neurodegenerative disease. Patient concerns: In preliminary clinical work, we identified a family with rapid progressive dementia. Diagnosis: Within this family, all patients had a CSF1R gene c.2696delA mutation (a deletion mutation), and head magnetic resonance imaging ...
en
https://cdn.wolterskluwe….0.x/favicon.png
LWW
https://journals.lww.com/md-journal/fulltext/2019/05310/diagnosis_of_hereditary_diffuse.40.aspx
1 Introduction Hereditary diffuse leukoencephalopathy with neuroaxonal spheroids (HDLS) is a rare disease involving white matter lesions of the central nervous system, and it is usually inherited in an autosomal dominant fashion. It is a neurodegenerative disease with obvious clinical and genetic heterogeneities, and ...