sequence stringlengths 13 8.92k | annotation listlengths 2 214 | description stringlengths 61 12.1k | labels int64 0 0 |
|---|---|---|---|
MTIRHILAIRKKSLELPSDLKTFLRVLANCQHLKKNKKCRRTIFSVDFQNNQRQKPSNFHFWTVIKKFSKKILKSFIIKFGNNGTIAVVFSIFPTGATPSLTFLFQALGKGAYGNVYRVRSLHDGKDYALKQIMISSKNEGIPQSVLREITVMKHLARKAHPNIISLKSVFHQLDPVRAILKINMIMERCDWDLHTFLRNIPRGVPEQQAKHVTAQIVRALDFLHTHSIIHRDLKPQNILLNRDQTVKLADFGLSKEYSNTTAFTTLVVTLWYRSPEVLLQSYYNSTVDMWALGCIVSEIYCRQPLFVGQNEAEQLTDIF... | [
3618,
6665,
7198,
8663,
8930,
9095,
9461,
9839,
9888,
12520,
14984,
16787,
20039,
21266,
24746,
24917,
24978,
26858,
28524,
28536,
29033,
30938,
32536,
35176,
36535,
42974,
45290,
50333,
75763,
87016,
87110,
87139,
87272,
87273,
87694,
87747,
8... | The following text describes a protein:
Function:
Serine/threonine-protein kinase which, in association with cyclin D-like protein cyd-1, is required for the progression through the G1 phase of the cell cycle during postembryonic development by phosphorylating and inhibiting lin-35 and fzr-1. In complex with cyd-1, inv... | 0 |
MRFRFCGDLDCPDWVLAEISTLAKISSVKLRLLCGQVLKDLLGGGIDYEKILKLTMDARFESGDVKATVAVLSFILSSAAKHSVDGESLSSELQQLGLPKEHAASLCRCYEEKQSSLQARLRACSLRVNRLVGVGWRVDYTLSSSLLRTVEEPLVHLRLEVAASPGAPAQPVAMSLSADKFQVLLADLKQAQTLMSNVG | [
8663,
24917,
24978,
50772,
65029,
73129,
87367,
87857,
88008,
88148,
88150,
88181
] | The following text describes a protein:
Function:
Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (By similarity). May modulate activity of cullin-RING E3 ubiquitin ligase (C... | 0 |
MAAGFVLTPHKLSMCVLLQLYAAPPALTPPFPLPAAVRHQLALFLLGLAKACDGFLEPTLEDLGMQLKECLGSIGEVIAEQLASRLLGFSSPEDLFTFVVLGLRGKLFRGGGNEDSLLVEHNSPLGQFLRRCILSFNILSFEGTCRLLAELDAYRRPALSIGDGNIVAKDSLSCQQAEGDDDEDEEEDRLEDDEDENVIASVTPVHGRERHGNGRRAFGVPLIPTEEMHRVRVALLPLTGFVKRVEQVHYLQYLNSIHHGDYPAAMSRLHQYFDYSVGRFQAGLLTLGSMHAHFGHVTQALQASFSALTIHLTFSMQNND... | [
11950,
15361,
16787,
18697,
24944,
46079,
57403,
65287,
87272,
87273,
87790,
88008,
88058,
88181
] | The following text describes a protein:
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of targe... | 0 |
MVLWSAKSKLYLCFLAFLIASLIGRSTASLGDHLPDFKECVKICQAENCRDGDSIIPLHLRLLLWTCPAECDYTCQHVVTDRRLARDPPMLNPVVQFHGKWPFRRILGMQEPFSVLFSLLNLLAHWNGIGRIKETVPAWHSLRPYYLTFGYCGLACWTFSMLFHTRDFPLTEKLDYFGAGANVMYGLYLAIIRILRLDQGKPRYKPTLRRLTTTICVLLYTMHVCYLSFWSWDYTYNMIANVVVGAIQNILWTGFSIVRYQKQGKVWMAWPGMIVVWIMLAMSLELQDFPPWHGLIDAHSLWHLGTVIPTAWWYMYLIKD... | [
8198,
11585,
24759,
25014,
30333,
42073,
87432,
87490,
87760,
88008,
88058,
88159,
88161
] | The following text describes a protein:
Function:
Involved in the lipid remodeling steps of GPI-anchor maturation.
Subcellular Localization:
Endomembrane system; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. | 0 |
MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPYLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANCWERCR... | [
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21863,
24978,
25650,
35915,
36115,
41591,
45551,
45807,
49045,
50020,
59882,
87139,
87272,
87273,
87691,
87790,
87976,
88008,
88009,
88181
] | The following text describes a protein:
Function:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL18) E3 ubiquitin ligase complex mediates the ubiquitination of AURKA leading to its activation at the centrosome which i... | 0 |
MPLLPAALTSSMLYFQMVIMAGTVMLAYYFEYTDTFTVNVQGFFCHDSAYRKPYPGPEDSSAVPPVLLYSLAAGVPVLVIIVGETAVFCLQLATRDFENQEKTILTGDCCYINPLVRRTVRFLGIYTFGLFATDIFVNAGQVVTGNLAPHFLALCKPNYTALGCQQYTQFISGEEACTGNPDLIMRARKTFPSKEAALSVYAAMYLTMYITNTIKAKGTRLAKPVLCLGLMCLAFLTGLNRVAEYRNHWSDVIAGFLVGISIAVFLVVCVVNNFKGRQPENEHIHTDNLAQMPMISIPRVESPLEKVTSVQNHITAFAEV... | [
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15857,
25079,
29136,
36208,
64663,
69888,
87276,
87760,
88008,
88159,
88161
] | The following text describes a protein:
Function:
Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory-mediated axonal retraction.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. | 0 |
MAAMYLQNQGFEEYASARRLSEEESRQDPETEPYKSKYKARELLLQLAEALQGFQDESQAEENIELTLQLAELWFHLGVNFSETEEVPTGEQYFSRCAELMQGHKMDQRCVNTCLNCLNQLGILWVSRSEPEKALKILQEAEDIYKMYMHNVGQPPLLLHELLSPEQTGSPKSRQAEFEKTHTLTLYYLAQTYPKLGDNEKSAAYCHLTLSRQLQSGHFQPIDWATNCATLSQYYVTRDNFTQGRHCLASASSVLSQVPEPSDETEDGENESAREKLERRKADISRCWLKYCLVLLQESRQALMDDIGELDRAKQTDLAK... | [
6686,
11495,
23859,
24978,
25057,
46079,
54065,
87367,
87371,
88008
] | The following text describes a protein:
Function:
Activator of KIF1B plus-end-directed microtubule motor activity. Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.
Subcellular Localization:
Cytoplasm, cytoskeleton. | 0 |
MKKGADTMNTIKKIKNIYPLSHMQEGMLFHSFLRKEEGAYVEQSLFTIKGSLSYDWFQRSIQAIIDRHDIFRTVFLPHVPHLSGPRQVVMTEREFHLNSEDISHLPTNDQNEYIERFKEKDKQKGFDLQKDMLMRISLFKTAKDEHVCIWSHHHILMDGWCLGIVMQEFMQIYQSIHAGKPLSLDPVRPYSTYISWLTNRDKEKAAAYWDTYLKNYSAPSPLPRVSDKETKESYHREDLIFSLNKPLTDKLKETAKQHGVTLATLIQAVWGVMLQQYNRTDDVVFGAVVSGRPSEIPGVEQMIGLFINTIPIRIKTHQDE... | [
2459,
9106,
10762,
14458,
14908,
24978,
25040,
30298,
31094,
36668,
36798,
36974,
41154,
43643,
44483,
52757,
52907,
52910,
52940,
55053,
56598,
59224,
64475,
72011,
87088,
87159,
87814,
87913,
87914,
88008,
88153
] | The following text describes a protein:
Function:
This protein is a multifunctional enzyme, able to activate and polymerize the amino acid Ile as part of the biosynthesis of the lipopeptide antibiotic plipastatin. The activation sites for this amino acid consist of individual domains. | 0 |
MSQGLTAYRNVLRAANLAFKNDHFVLGQAKANIRKGFEDGRKLDPKDEDVKVRLEHINGVAYVLRTQVVQGQKHNPDEEKYQLNLHKDSEMGDNESIKSPPPMPTKGKKGKKVKCCSE | [
13061,
24988,
32341,
71508,
76090,
87285,
87785,
88008,
88154
] | The following text describes a protein:
Function:
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII ... | 0 |
MTSFSAPGSPVDTVLLTSPAGAGRTEAIRIFEDLGYLCLNHVWPELVPTFLKHYAPIAPRLVLCLASRPEADAQAGLIAARVALRSLARTTVHVHLDCPEGVLLSRYALTRRPHPWFDHGKGLLAAIRAERTALEPVRALADEVVDTGPLELAQLRVHLGALVGGRPTELPVTVMSFGFKRGVPADAQFVLDIRFLPNPYYESALKPLTGLDVGVAEYVFASEQSQATYRSLLEFLRFLLHQYRQDRRSQLLIAIGCTGGQHRSVAFVERLSGDLAAEGFACRPSHRDLAVNRLQELSR | [
29033,
29034,
34060,
40413,
58239,
79562,
79563,
87110,
87491,
87855,
88008
] | The following text describes a protein:
Function:
Displays ATPase and GTPase activities. | 0 |
MSSSPAVKGLTDEEQKTLEPVIKTYHQFEPDPTTCTSLITQRIHAPASVVWPLIRRFDNPERYKHFVKRCRLISGDGDVGSVREVTVISGLPASTSTERLEFVDDDHRVLSFRVVGGEHRLKNYKSVTSVNEFLNQDSGKVYTVVLESYTVDIPEGNTEEDTKMFVDTVVKLNLQKLGVAATSAPMHDDE | [
9430,
24917,
24978,
25079,
26569,
28676,
29722,
31958,
32073,
32074,
52108,
55189,
75934,
87103,
87112,
87276,
87367,
87760,
87857,
87971,
88006,
88008
] | The following text describes a protein:
Function:
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA. Can be activated by both (-)-ABA and (+)-ABA.
Subcellul... | 0 |
MSLITIFAFFIKATLVLSLDILTPTTLTGDQTFNEDVSVVSSLTLNDGSQYLFNNLLQIAPSSASVTANALAAVSVFTFSLPPSSSLSNSGTLIISNSNTGPSTEQHIVITPNVMANTGTITLSLAHTNTDSSSTLIIDPVTFYNTGTINYESIGSETNDPSLTGNILSIGSSGRTLQNLGTINLNAANSYYLLGTITENSGSINVQKGFLYVNALDFIGNTINLSTTTALAFISPVSQVVRVRGVFFGNIIASVGSSGTFSYNTQTGILTVTTNGVYSYDIGCGYNPALMSGQQETLSFQGNLYDTFLVLVNQPIPSDL... | [
8653,
11640,
24878,
25166,
25571,
30875,
34711,
45286,
75804,
87103,
87270,
87280,
87413,
87522,
88008,
88038,
88058
] | The following text describes a protein:
Function:
May play a role in cell adhesion.
Subcellular Localization:
Secreted, cell wall. Note=May be GPI-anchored. | 0 |
MNVPVGHLRNVQVLGIDAGGTMTDTFFVDQDGDFVVGKAQSTPQNEALGLIASSEDGLANWGMSLHEALAQLQTGVYSGTAMLNRVVQRKGLKCGLIVNRGMEDFHRMGRAVQSHLGYAYEDRIHLNTHRYDPPLVPRHLTRGVVERTDMIGTQVIPLREDTARDAARDLIAADAEGIVISLLHSYKNPENERRVRDIVLEEVEKSGKKIPVFASADYYPVRKETHRTNTTILEGYAAEPSRQTLSKISNAFKERGTKFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALI... | [
6521,
8400,
21049,
25040,
29033,
30500,
30628,
38267,
42801,
69819,
71302,
75259,
87007,
87016,
87039,
87103,
87110,
87722,
87855,
88008
] | The following text describes a protein:
Function:
Catalyzes the carboxylation of acetone to form acetoacetate. Has a reduced activity on butanone, and no activity on 2-pentatone, 3-pentatone, 2-hexanone, chloroacetone, pyruvate, phosphoenolpyruvate, acetaldehyde, propionaldehyde and propylene oxide. | 0 |
MAGKAGRKQASSNAKIIQGLYKQVSLFLGMAIVRLFISRKVTIGQWIKLVALNVPMFVALYIIVLSGKPKYDGNRVVKQGIDLNDNTNLISYFFDLIYLSLFGNIGIIAFRTFKFWWCLLLCPIYAGYKLYGLKNMFMPGAQQTQADNRSKNANEGQSKSKRQMKRERRGETDSKIKYKYR | [
8299,
10368,
25000,
25008,
25014,
26230,
43174,
87432,
87760,
87974,
88008,
88159,
88161,
88162
] | The following text describes a protein:
Function:
Functions in the SND pathway, a SRP (signal recognition particle) and GET (guided entry of tail-anchored proteins) independent pathway for targeting a broad range of substrate proteins to the endoplasmic reticulum. SND functions in parallel to GET in targeting proteins ... | 0 |
MTRMTRHLALWMLLSLAILASQSAMAQKLPDFTSLVEEAAPAVVNISTSRTVETRNMPFGQFGGQELPEIFKHFFGERFGDQMPMPPGAQGHSEERRSLGSGFIISEDGYIMTNAHVVEGADEILVSLNDGRELKAELVGADTKTDVAVLKVDADNLPTLTLGDSEDLKVGQWVAAIGSPFGLDHSVTSGIISAINRTLPRDVYVPFIQTDVAINPGNSGGPLFNLDGEVIGINSQIFTRSGGYMGLSFAIPIDVAMDVADQLRNDGSVSRGWLGVMIQPVSRELADSFGMDKPQGALIADLDPDGPAARDGLKAGDVVL... | [
4581,
8200,
25488,
28227,
37172,
37554,
43583,
45876,
63819,
87601,
87892,
87965,
88009,
88049,
88058,
88086
] | The following text describes a protein:
Function:
Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.
Subcellular Localization:
Periplasm. | 0 |
MKGPEKAYLVSDKATKMYSLTLDSSEKNNFSKPPLQDHENPRIKYHCHNNNTKAYDARQKEQALAKKKLCIASLICFIFISAEIVGGYIAGSLAVVTDAAHLLVDLSSFFISLCSLWLSSKTSTMRLTFGWYRAEILGALLSIITIWLVTGVLVYLAIERIIRPDYTIDGTIMLITSACALGANLILTLILHQPGHGHSHAGGKHEHMASDYKLQTNASIRAAFVHVIGDLFQSISVLISALIIYFKPEYKIADPICTFIFSVCVLITTMTVLRDLLTVLMEGTPRGIHYCDVKQSILAVDGVKSVHSLHLWALTMNQVI... | [
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9619,
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25079,
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28988,
29924,
32536,
38031,
58277,
58278,
64569,
76336,
87164,
87276,
87369,
87676,
87760,
87767,
88008,
88159,
88161,
88162,
88261,
88262
] | The following text describes a protein:
Function:
Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle m... | 0 |
MSKAAAPQIELASADPSIAQEMTRWLSHLGAERRLSPKTLEAYGRDLRQCLDFLCNHWGERVTLKRFAALEATDVRAFMAMRRADDIAGRSLMRALAGLRSFGRFLEREGKGKVGALSAIRAPKVAKSLPKPLPMASAKRLADADERAGEERETWILARDAAVMALLYGSGLRISEALGLKRREVPKPGEGDVLVVTGKGNKTRMVPVLQNVLALVQEYVSMCPYPLPAEGPIFVGARGGPLSPRIIQLAMERLRGALGLPDSATPHALRHSFATHLLSRGGDLRAIQELLGHSSLSTTQIYTGIDSERLLEVYASAHPR... | [
8084,
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8603,
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18740,
24978,
26466,
27904,
29620,
37685,
39305,
45282,
45291,
47518,
54889,
70372,
75745,
87272,
87273,
87307,
87367,
87377,
87379,
87384,
88008
] | The following text describes a protein:
Function:
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also ... | 0 |
VLTEQEEDSSQLQFPQEFESAETLLNSEVHMLLEHRKSQNENADDEQELSEVFMKTLNYTQRFSRFKNRETITSVRGLLLQKDLHKFELASLANLCPETAEEAKALVPSLEGRFEDEDLQQVLEDIQTKRSFQ | [
8111,
24934,
27656,
31106,
40626,
41543,
45281,
65826,
71437,
87386,
87857,
88008,
88148
] | The following text describes a protein:
Function:
Core component of RNA polymerase II (Pol II), a DNA-dependent RNA polymerase which synthesizes mRNA precursors and many functional non-coding RNAs using the four ribonucleoside triphosphates as substrates. Pol II is the central component of the basal RNA polymerase II t... | 0 |
MEQGKHLAGLILAVFLLQGTMAHVKEVKVDDNREDGSVILICVTNDTTITWLKDVEQIGSGDTKKNTWNLGSSTKDPRGIYKCEGSNNQSKSLQIYYRMCQNCIELNPSTVAGFIFTEIVSIFLLAVGVYFIAGQEGVRQSRASDKQTLLNNDQLYQPLKEREDDQYSHLRKN | [
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8664,
15033,
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26132,
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38485,
38877,
47529,
48896,
60898,
63951,
87126,
87276,
87413,
87522,
87616,
87618,
87760,
87914,
88006,
88008,
88058,
88159,
88161
] | The following text describes a protein:
Function:
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chain... | 0 |
MLKDAHQKLIKHRQSTKLSMTDFACQAAPVKQPLPLELPLPLSVQLQLLAKTPTSDHAPMHSTPPTTPPTPPPLPLNMSQSASAVTEAATPENSLPATPPSEGALAVPSAPQDHYSLRWNNHQNHILRAFDALLKTKTLVDVTLVCAETSIRAHKMVLSACSPFFQRVFAETPCKHPVIVLKDFRGWVVQAIVDFMYRGEISVPQQRLQTLIQAGESLQVRGLVESSVPEHTPTPAASPDDFGMLDTSMLSSTFEDECPTMVRPSKGGKLLMPSARLFGNASSAIAALGLRRKREQESDRDLESDQELGGSSPMPRRKQA... | [
8103,
8842,
9008,
9071,
11761,
14161,
15946,
16123,
24917,
27904,
36115,
42675,
43624,
45551,
76749,
87384,
87857,
88008
] | The following text describes a protein:
Function:
Has a regulatory role during midline cell development.
Subcellular Localization:
Nucleus. | 0 |
MEGDSYHNATTVNGTPVYHQPLERHRLWEVISIAAVTAVVSLITIVGNVLVMISFKVNSQLKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTPKRAGVMIGLAWLISFILWAPAILCWQYLVGKRTVPLDECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTEAEKRKPAHRALFRSCLRCPRPTLAQRERNQTSWSSSRRSASTSGKPSQATDPSTNQAKAEQLTTCSSYPSSEDEDKPATDPV... | [
6943,
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8689,
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10529,
10949,
25079,
25495,
26413,
26414,
30412,
36171,
36352,
36766,
50338,
87276,
87413,
87484,
87522,
87760,
87914,
87943,
88006,
88008,
88097,
88152,
88159,
88161
] | The following text describes a protein:
Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
Subcell... | 0 |
MTGDVCPSSRDLERALSLPMVEAFHVSAWYVLQYYEKAIDSSDLLSLRGLITLSLNNLCRSEEAADGIEAFELLLRMALRDAKWLRVRCIETQYSCFIRVASALEELNITPIAKYVISDTRSEGEQLVRVLDGKAIFRPPLGCREEIREILRTARVHELQQLDRCVRYEDGPPSHNHSAVHYTLAGNHSYGGESITGVQTAGRSSWNAKGCSSRLLPEKEDLIDRILSVSDEEGQLASAWDRTVGPICCVHQLFRDSILKISELIHEVTAPSIRDDICKYPGSAPAGCRSSDTTILKIVSKLMLRQSSDLRGPWMLWPQA... | [
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13741,
24917,
24978,
25716,
28409,
29217,
30477,
32536,
34291,
48385,
61717,
87016,
87017,
87374,
87380,
87601,
87747,
87752,
87767,
87850,
87857,
88008
] | The following text describes a protein:
Function:
Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
Subcellular ... | 0 |
MSHLFPPSSPVAGKPLESPQKEPGKLANTSVLTLGRKRYNYELEEYPTPDPSSSIGRQSSPVKDITSRLNETKSALSSPSKQEKVLAGPIEIELDASDPSRLAIGRKKSVCNIILPCRKNISRQHAFISYAADRNEIKLECNGTNGLSVHLPYSMQLHLVKPFPTRNFYKLVAEEPLTSQNTKQSHGKTLQKNQNFISFVLAKGETVTFPYIQGSFINFTGVTVCLSLKKVAPYPGDGNNNFDEENSTETEDELCLLTTTSDDFSWQKETPSMKFVPVEHSPRTEQISKPLLIASPALVKNSPISYRTTPQTSFVINQPS... | [
8549,
24788,
24917,
27908,
36151,
43568,
87857,
87914,
88008
] | The following text describes a protein:
Function:
Binds to the promoters of genes with functions important for the G1/S (start) transition; primarily genes involved in DNA synthesis and repair, chromosome segregation, nuclear division and transcription.
Subcellular Localization:
Nucleus. | 0 |
MKTLIKRLQDQQDIWKRIEIVGDIVIIGVPFNKKPEDLVEIANEILSTFPYVKSVWGRHRDVNGTYRLSTYVHLAGEKRSETVYKEHKCKYFLDFTKVFFSEKLSYEHLRVATQVKRDEIIINMFSGFGPFSILSAVLGRPKIVYSIDLNPYAYYYMMVNVELNKAYEVLPIYGDAFKRIYELEDADRIIAPLPELADKAYEVALQKVKKGGIIHLYTEVETNKGEDPVRIAMNKYRGSYFGRIVRSVNPHKYHVVVDIKAN | [
2070,
7600,
24978,
29123,
59229,
59793,
87367,
87777,
88008,
88026,
88153,
88278
] | The following text describes a protein:
Function:
Catalyzes the C7-methylation of 4-demethylwyosine (imG-14) at position 37 in tRNA(Phe).
Subcellular Localization:
Cytoplasm. | 0 |
MKMNHFRFDNFSTVPPDPVLTISGYTTGVSAGQSLPLTCTSTQGKPPAHVTWWNGDVEQQQAVYSSTPDSSTYQGDATSVLTLAVQPANNQETYQCRVSQLETELERQNVQLNVRFMTGPPTLTGYSGPINTGSSLTLTCTTGSSNPPASISWTLVGGSASSATFPSDTEGQYGGTITSEQTILPNQRPQDNGSQIKCTATKSELGQSMDSSTVTINVRFYLGGIGITGHTNSVTSGSSLTLTCTSGSSNPPANISWTRVGGAAPTGTDQPQTDGQHGGKITSQQISLTNLQAQDNGAQFKCTVTNSAVSQREEKTVTID... | [
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88006,
88008,
88009,
88058,
88153,
88... | The following text describes a protein:
Function:
Receptor for basic fibroblast growth factor.
Subcellular Localization:
Membrane; Single-pass type I membrane protein. | 0 |
MYALTNCKIYTGNDVLVKHAVIINGDKIEAVCPIESLPSEMNVVDLNGANLSPGFIDLQLNGCGGVMFNDEITAETIDTMHKANLKSGCTSFLPTLITSSDENMRQAIAAAREYQAKYPNQSLGLHLEGPYLNVMKKGIHSVDFIRPSDDTMIDTICANSDVIAKVTLAPENNKPEHIEKLVKAGIVVSIGHTNATYSEARKSFESGITFATHLFNAMTPMVGREPGVVGAIYDTPEVYAGIIADGFHVDYANIRIAHKIKGEKLVLVTDATAPAGAEMDYFIFVGKKVYYRDGKCVDENGTLGGSALTMIEAVQNTVEH... | [
4896,
7907,
10969,
16776,
29244,
32536,
39010,
41613,
45332,
61222,
87052,
87103,
87258,
87601,
87767,
87838,
88008
] | The following text describes a protein:
Function:
Involved in the first committed step in the biosynthesis of amino-sugar-nucleotides. Catalyzes the hydrolysis of the N-acetyl group of N-acetylglucosamine-6-phosphate (GlcNAc-6-P) to yield glucosamine 6-phosphate and acetate. | 0 |
MGGASSPRIPSRRSAPYFTSLAFFGSSYIKVKNNRNKMLNPTDAASVALSFSVPFQMSGENPLSKLVEHCNKFVPGADIKMKAEPAKPESLLLPTDMNAYSPYLATPNWWVDQTGWPQLYPTVTTASSVDVYQNYLASSQLGGLLSSSVSAVASQLPAGINAQSALNITSQQRTIAKSFQHTKPMASSSSIPSVLTASNSSANSLVSSGSESVSARGTSGSGGTGKYPSSRTANKCECPNCHEIEKFGPNAIAARKRGVHNCHIAGCGKVYNKSSHLKAHLRWHSGERQMKKRSGDSS | [
9989,
11632,
29166,
46932,
64003,
87139,
87767,
88008,
88148,
88150,
88261,
88263
] | The following text describes a protein:
Function:
Probable transcription factor which modulates gene expression, thereby acting as an ASJ sensory neuron terminal selector gene. | 0 |
MQEIITNNIPTFKLQNDVDMVEETQPTTPTTQPTTPTTNTISTTTNTITSTLNTNNISPILEESEEEDSNELIIETDENNTSVSATGTTPTSSSSSSSSSPTNTTTTTTTTTTATTANNDFKNITSNNINKTNSNVNTNSEIKNIDNSIMNSLNRYNNITTASPSNSTMITMKSAISSLDEIVKNTMKAQRESFIANEDKESLPEPQTNSNVNGNEEAKDEKEIHLLAKILLNFSSNGIAVPNLSESSPAVLNTKLKDSSNLVPYGGDLNTSVNGVVGNSSGMVDLSASTGDLLGSLNAANKKKRQRTSPEQLAILEQIF... | [
8103,
11620,
24917,
27733,
27735,
37071,
43624,
50806,
76654,
87384,
87402,
87566,
87857,
88008,
88148,
88150
] | The following text describes a protein:
Function:
Putative transcription factor.
Subcellular Localization:
Nucleus. | 0 |
MHFVSYSLCYDVRSNIMEQPIYFYEPDENHGFLANFYPCSITVSGTCWPSSEHYYQAQKFDDVRLQEKVLRAEDAAQAFRLSREYQQWQRHDWYDIRVEVMRFIVREKFLQNTPLAHQLLATGDTELKEHSHKDAFWGDGGDGHGRNELGRILMMVREELQEHAPYNLVQFIDSAKLPTQWGTFQMYGFIEKATGKEHLALVYGDIEQQAAPLIRLHSECLTGDALFSARCDCGFQLAKALQNIVAEGAGVLLYLRQEGRGIGLINKIRAYHLQDDGADTVEANEQLGFGADMRDYAFCRGILSFLGIERVRLMTNNPRK... | [
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46713,
61394,
63920,
64932,
87039,
87491,
87523,
87601,
87767,
87814,
87855,
88019,
88261
] | The following text describes a protein:
Function:
Catalyzes the hydrolysis of the N-glycosidic bond in the first two intermediates of riboflavin biosynthesis, which are highly reactive metabolites, yielding relatively innocuous products. Thus, can divert a surplus of harmful intermediates into relatively harmless produ... | 0 |
MVSHYYNTLPYTQKHSAANLAYASAAGQPWNWTPNYHHTPPNHQFLGDVDSSHAAHHAAAAHQMYYNSHHMFHSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIW... | [
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8809,
8811,
8861,
8862,
8892,
9051,
9518,
9557,
9591,
11620,
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13258,
15388,
15427,
16181,
24917,
24978,
27732,
27735,
27918,
35988,
37071,
43624,
50806,
52772,
73127,
87139,
87384,
87402,
87501,
87566,
87857,
87914,
8800... | The following text describes a protein:
Function:
Caudal (cad) is one of a number of transcription factors controlling segmentation of the embryo. Further transcriptional regulation via a 5' flanking region containing DNA replication-related elements (DRE) and by dref also regulated by trh and tgo via the CNS midline e... | 0 |
MQNSHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQQQEGQGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASNTPSHIPISSSFSTSVYQPIPQPTTPVSSFTSGSMLGRTDT... | [
6673,
6675,
6909,
6954,
6976,
6982,
7161,
7165,
7168,
7182,
7605,
7771,
7772,
7780,
8095,
8103,
8110,
8710,
8828,
8832,
8833,
8834,
8835,
8844,
8847,
8857,
9050,
9350,
9457,
9559,
9561,
9562,
9887,
9888,
9989,
10212,
11257,
11264,
11288,
... | The following text describes a protein:
Function:
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells. Competes with PAX4 in binding to a common element in the glucagon, insulin and somat... | 0 |
MSGNVLFAMITRLRDGLPLSATTDHDPSQRVLESKKYAKIISKKASQFPDRCSMFTGSHWLYFISSLGVCFITMCEESYSSVLAFCFLDELQREFISLYDNKRVDNAVRPYALIDFDRIIQKTKQRYNNPMTLNARQKYSDMTLEVKLRPPYRISIDDLEPTGRRNVNGISAHHIPTWQAVNLSDTEDIPKPTNFRRPFSRLDWMAKLLVFLSVLCGTLNLARIMAVLTFGTSPYEPDEKVIVAQAMALLIIAALLSYYQSFKLWTSLGQRSLRQLLACVLVIVCNYSLYKLYWRFLLTAGFHSLVAVLVAWKMRAGSGD... | [
8492,
25014,
45209,
45293,
70023,
87432,
87760,
88008,
88159,
88161,
88162
] | The following text describes a protein:
Function:
May be involved in vesicle transport between the ER and the Golgi complex.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. | 0 |
MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDTRTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVCQPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG | [
4035,
9233,
25040,
30156,
30333,
30334,
32073,
34082,
38984,
41615,
57840,
59235,
87103,
87367,
87601,
88008
] | The following text describes a protein:
Function:
Required for optimal enterobactin synthesis. Acts as a proofreading enzyme that prevents EntB misacylation by hydrolyzing the thioester bound existing between EntB and wrongly charged molecules. Displays esterase activity toward a wide range of substrates, including acy... | 0 |
MVTDIASCLPLFPVSHDFIDIINEPAQFREALKKGIETARSRIVLASLYIGTTETDLIEELRMALQSNSQLRLIVLVDYFRGSRIEGNGKSTVNLLEPLRDLYPNQVQISLYKSPAAKRKWMGIVPQRFNEIFGLQHIKAYVFDDDVLISGANISKDYFTNRQDRYVLFRKAGDMALYFTELIQTLANLSEASLKISESRKEYLDRVHNTLESFSAVWLKKTQIFRNQFNTIFKDNLTDSDGCTFAAPALQLGCVGIRYDQKAMLCALSLAREAPDYHISIASGYLNFPSVYRDVLYQSKSDIEVLCSSPQANGFFNSRG... | [
3823,
12168,
24979,
29033,
29240,
37388,
49305,
87110,
87728,
87731,
87785,
87855,
87909,
87911,
88008,
88009,
88153
] | The following text describes a protein:
Function:
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
Subcellular Localization:
Mitochondrion. | 0 |
MSAMVSALTQVVSARSQTEAEGAHSSSSSAGHKRGWLGIDSAPIPSSFARVDSSHNPIEESMSKAFPEEAREKKRRYRGVRQRPWGKWAAEIRDPHRAARVWLGTFDTAEAAARAYDEAALRFRGNKAKLNFPEDVRILPPPPPLLRSPADTVANKAEEDLINYWSYTKLLQSSGQRSFLERGQEESSNIFEHSPMEQPLPPSSSGPSSSNFPAPSLPNT | [
9515,
15388,
16144,
24917,
27904,
27918,
37168,
49227,
64679,
71050,
87123,
87384,
87441,
87857,
88008,
88148,
88150
] | The following text describes a protein:
Function:
Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
Subcellular Localiz... | 0 |
MPSTTLLFPQKHIRAIPGKIYAFFRELVSGVIISKPDLSHHYSCENATKEEGKDAADEEKTTTSLFPESNNIDRSLNGGCSVIPCSMDVSDLNTPISITLSPENRIKSEVNAKSLLGSRPEQDTGAPIKMSTGVTSSPLSPSGSTPEHSTKVLNNGEEEFICHYCDATFRIRGYLTRHIKKHAIEKAYHCPFFNSATPPDLRCHNSGGFSRRDTYKTHLKARHVLYPKGVKPQDRNKSSGHCAQCGEYFSTIENFVENHIESGDCKALPQGYTKKNEKRSGKLRKIKTSNGHSRFISTSQSVVEPKVLFNKDAVEAMTIV... | [
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9003,
15388,
15427,
24917,
24978,
25079,
27733,
27735,
27788,
29166,
46932,
64003,
77296,
87276,
87384,
87760,
87767,
87857,
87914,
88008,
88009,
88261,
88263,
88264,
88278
] | The following text describes a protein:
Function:
Transcription factor involved in the regulation of gene expression in response to extracellular amino acid levels. Synthesized as latent cytoplasmic precursor, which, upon a signal initiated by the plasma membrane SPS (SSY1-PTR3-SSY5) amino acid sensor system, becomes p... | 0 |
MAAGRLGELWMKFWVPPRPALKVDKKTLERTWKLMEKVMRLCQSDKMKLKNSPPFILDILPETYHHLRLVWSKYEGDDKLPDLVENEYFKIFVDNINKKAKQTIQLFKDNKEKMYDESSTCRRQLNRMSLIFSHNLAELKALFPNGLFAGESYRITKADAAQFWKKNFGSRTIVSWKIFRQALTEVHQVRSSMETFALKTTIDLTRNDYISNFEFDVFTRLFQPWSTLLRNWNCLAVNHRGYMSFMTYDEVKNRLEQYISKPGSYIFRLSCTRLGQWAIGYVTQDKTILQTIPQNKSLCQALIDGNREGFYLYPDGCEDN... | [
2741,
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8664,
10753,
14048,
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27847,
29025,
29166,
31074,
34103,
37468,
38525,
46081,
46929,
48264,
48265,
50763,
55836,
55839,
64281,
64590,
66847,
87244,
87767,
88008,
88153,
88181,
88261,
88263
] | The following text describes a protein:
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
Domain:
The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a... | 0 |
MSDKGIFRTSSTPSIVDVTPDRGERPRKLVRSVLESPSQKDVASIVKIEQTPSRPFFNDFLKKRITDSLNERPNLLNKFMSAQDGTPSKSTGFNERSSQLVSEFTTTEDIENCEETTQVLPPRLVVYELRLTNFKSYAGTQIVGPFHPSFSSIVGPNGSGKSNVIDALLFVFGFRASKLRQSKASALIHKSATHPSLDSCDVEITFKEVNSDFTYVDGSELTVRRTAYKNNTSKYFVNGVESSFSAVSNLLKEKGIDLNHKRFLILQGEVESIAQMKPRAISEGDDGLLEYLEDIIGTSKYKPIIEENMQELSNSDDICA... | [
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24795,
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29033,
30060,
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38702,
45233,
56312,
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87110,
87272,
87273,
87306,
87326,
87367,
87373,
87790,
87855,
87857,
87914,
88008
] | The following text describes a protein:
Function:
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and conv... | 0 |
MGDDGCSLSPAELTEQQLSSQELEKALCEGSVSSPVRSNRGQDQTRLPSAVSQKTEWMHLPTTPGEGQERQRENRFCGIQGHHLVCHSLHASVDKKGRRRIRTTFTPEQLEEMEKIFQITHYPDVYTRDELASKTKLPEGRVQIWFQNRRAKWRKHEKLGNFGELQYMTEVDTVPAPRPSPGGDGTLPHEHTDISFLPGCNLLPTKLLPAGLHQQHFTPYHPASAFTAPFPHVLLCYLPPGHPCIFPNLLPTLRKTLS | [
8103,
16253,
24917,
27732,
27735,
37071,
43624,
50806,
76304,
87123,
87384,
87566,
87857,
88008,
88148,
88150
] | The following text describes a protein:
Function:
Transcription factor that regulates gene expression in intestine. May participate in vitamin A metabolism most likely by regulating BCO1 expression in the intestine.
Subcellular Localization:
Nucleus. | 0 |
MTTSELIERINKLIDVVDKAINKREFYPPRLTKYETARIIGARALQLAMGAQPLVDIQEVGSVDPVLIAMEELRRGLLDFIIVREMPDGKTMRIRLKELLELERTL | [
3740,
8105,
8110,
14372,
24773,
24978,
27904,
28007,
41107,
41108,
52880,
63933,
87367,
87386,
87856,
88008,
88148,
88153
] | The following text describes a protein:
Function:
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Subcellular Localization:
Cytoplasm. | 0 |
MSGIPEGEAGAALRALLTDSVVGLAVWDTGLRCVWVNDALERYDGIARERRLGRRPRESLTGDTGELEALVRRVLATGRCVTGREYRVPTAPDSRRDRAFSASFVRLHDDGGHILGVCMLMLVVTDRRWAGDRLAVVSEAGTRVGTTLDVMRTAQELADFTVPLIADYVTVDLTEAVRLGEEPLDRLGRSQGRVPKFRRAGRASVHAGSPESLWLNGEVVYVPETSPFMQVLSSGRPLLHPVLDPSHEAWLADDPARAAKIREFGMHSLLILPIHARGVLLGVAVFVRTSNPTPFDDNDRLLAEELVARAALSLDNARRY... | [
4108,
28554,
29033,
30159,
30335,
32536,
37549,
38412,
47420,
59186,
63761,
64206,
77668,
87110,
87601,
87694,
87747,
87752,
87767,
87855,
87914,
87970,
88008,
88153
] | The following text describes a protein:
Function:
Primarily acts as an independent SigF regulator that is sensitive to the osmosensory signal, mediating the cross talk of PknD with the SigF regulon. Possesses both phosphatase and kinase activities. The kinase domain functions as a classic anti-sigma factor-like kinase ... | 0 |
MTIIVVYLAMEEREALKKQIELLQTLINNHKSVHGDAPSGARTWSRPRQATASSQSRSTEFSRSHPAQTRPFESQPPGYWRKKYSLSNKHTAPEGTVVIHTGPAGTAVKSAVSSSVQHLPNQPVGPSSSSGVTADPQITSASATLLSGNSALTARQQSKGLLISKHQAALSSSLLLSSGLNNNLSQQNPVLLLSSQGSDTGLTGKSKTIKNSSLTQAVLIPKGSQNSALPSGPVSTSPQTCGLNENVQPKPSSLPRADSGDGSSGHVKPHFLSKSVKDPKPASSDPASITSHHITKITSSVLSSSSSQTDTGSDAGDKNA... | [
24917,
27904,
29166,
36409,
64585,
87384,
87767,
88008,
88009,
88261,
88263
] | The following text describes a protein:
Function:
Required for the export of polyadenylated mRNAs from the nucleus. Enhances ACVR1B-induced SMAD-dependent transcription. Binds to single-stranded DNA but not to double-stranded DNA in vitro. Involved in RNA cleavage. | 0 |
MTETDKKQEQENHAECEDKPKPCCVCKPEKEERDTCILFNGQDSEKCKEFIEKYKECMKGYGFEVPSAN | [
8449,
10857,
12808,
24979,
24987,
25040,
30221,
35772,
42547,
43633,
87103,
87285,
87346,
87411,
87413,
87767,
87785,
88008
] | The following text describes a protein:
Function:
Copper chaperone for cytochrome c oxidase (COX). Binds two copper ions and deliver them to the Cu(A) site of COX.
Subcellular Localization:
Mitochondrion intermembrane space. | 0 |
MEEKAKAEQKKIGMTETWLKKHRLLYNGATRHPLIISIRDGTINTASFKTWLAQDYLFVRAFVPFVASVLIKAWKESDCSGDMEVILGGMASLEDEISWFKTEANKWGISLSDVVPQQANKNYCGLLESLMSPDAEYTVAITAFWAIETVYQESFAHCIEEGSKTPPELKETCVRWGNEAFGKYCQSLQNIANRCLQKASDEELKKAEVMLLSVLEHEVEFWNMSRGNV | [
4844,
5043,
9225,
9226,
25040,
33469,
39484,
49154,
76622,
87413,
87601,
88008,
88128
] | The following text describes a protein:
Function:
May be involved in thiamine salvage. | 0 |
MFFSQPTHLAKAEELKQAPPKGVAYSVALPGTEQPGRSPVYRAWNAQKELLTTLDPEVTTAHDIFESTAIRHPKNDCLGWRPYNSTTKSFDPYQWLTYETVQKRRAAFGAGIVELHHKHDCHRPGQYGVGLWSQNRPEWQITDLACVSQSLYSVSIYDVLSEDATEYIINHSELSCVVTSLPHIASLIKLKPSLPTLKIIISLDPLDGGEQAGHSKRAIFESMAAGLGLAIYTIDQVEELGLASKRGYNPPSASDIVTINYTSGTTGPPKGVVLTHGNAVAATSCGLITISQARGDTSASYLPLAHIYARLAEHTAFWGA... | [
6322,
10645,
20999,
25007,
25008,
25325,
28355,
29033,
30388,
36668,
52940,
69093,
87110,
87722,
87855,
87894,
88008
] | The following text describes a protein:
Function:
Acyl-CoA ligase involved in the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 (By similarity). The peroxisomal acyl-CoA ligase 891 converts the intermedia... | 0 |
MSHQNLFSLILLFILVTRAESTVNRFRILEDESTVDVYHILEGGGEYNTFIKFLKETKVGDRINYKANSSDGVTVLAPTDNAFKNLINSISDDEHKLQQLINYHVISKFYEFDELQTVHNPVETLATGEDNEPLGLNFTGKKNQLNVSSGYVVTNVYEKAISISTDPPLAVYKLDKVLVPSEFIDPKSPSSNDAPAPAKAKNGTSDDDEITADDKPSPITAAATKPNDAKRINVGILCLISCVFLMGQLS | [
9490,
25079,
27013,
36588,
64136,
71233,
87276,
87489,
87522,
87735,
87760,
88008,
88058
] | The following text describes a protein:
Function:
May be a cell surface adhesion protein.
Subcellular Localization:
Cell membrane; Lipid-anchor, GPI-anchor. | 0 |
MSAAEAGGVFHRARGRTLAAFPAEKESEWKGPFYFILGADPQFGLIKAWSTGDCDNGGDEWEQEIRLTEQAVQAINKLNPKPKFFVLCGDLIHAMPGKPWRTEQTEDLKRVLRAVDRAIPLVLVSGNHDIGNTPTAETVEEFCRTWGDDYFSFWVGGVLFLVLNSQFYENPSKCPSLKQAQDQWLDEQLSIARQRHCQHAIVFQHIPLFLESIDEDDDYYFNLSKSTRKKLADKFIHAGVKVVFSGHYHRNAGGTYQNLDMVVSSAIGCQLGRDPHGLRVVVVTAEKIVHRYYSLDELSEKGIEDDLMDLIKKK | [
4108,
24878,
25040,
25079,
26018,
28555,
32536,
39971,
59218,
68879,
77570,
87052,
87139,
87367,
87601,
87767,
87914,
87976,
88008
] | The following text describes a protein:
Function:
Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.
Subcellular Localization:
Cytoplasm. | 0 |
MIEVPPFWCPLPIAIHPAADQAEKDARAWAERYGVRLRIADQVQPGRLGAYWAPHGTYEGMLAVGCWNFWAFAFDDHLDEPLPLDVPVTTSLVQQAVDIPSPPITDDPWAAGAQAVFNMFRDLATPTQVRYCADNHRRWLHGACWRHSNHVNRRLPPLAEYIPLRMQDAAAQATCLIAVLIGSDISVPEQEMDSPRVRALLETASWTATIDSDLHSFQLEDTQRPVSQHIVSVLMHERGIGVDEALRQSVALRDRFMTRFLHLQQECARTGSSELARFAHTLGYVISGYLQWAVDTSRYGQTEATFSFTDTPRDDTPEPP... | [
5685,
27681,
29710,
43545,
62730,
87016,
87741,
87747,
87767
] | The following text describes a protein:
Function:
Catalyzes the formation of the 5-9-5 ring skeleton (3S,6S,11R,14S)-tsukubadiene from geranylgeranyl diphosphate (GGPP) via a 1,11-cyclization and a 10Re,14Re-cyclization.
Domain:
The Asp-Asp-Xaa-Xaa-Xaa-Glu (DDXXXE) and Ser-Xaa-Xaa-Xaa-Ser-Xaa-Xaa-Xaa-Glu (SSE) motifs a... | 0 |
MKVARFEHIPNGENEKMIPVLTSKKASELPVNEVASILQADLQNGLKKCEVCHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGRLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKLTTPQPAATNGDLTSRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLQGKHILDMFTIGVSLAVAAIPEGLPIVVTVTLAL... | [
6559,
8451,
8480,
9092,
10716,
11593,
12339,
12343,
14446,
18556,
20307,
24724,
25008,
25024,
25079,
25782,
25833,
28989,
29033,
30398,
32536,
35437,
37404,
39222,
41074,
41379,
42956,
51063,
55054,
55120,
55121,
64168,
70765,
87110,
87244,
87247... | The following text describes a protein:
Function:
Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
Subcellular Localization:
Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane... | 0 |
MEGALTARQIVNEGDSSLATELQEEPEESPGPVVDENIVSAKKQGQSTHNWSGDWSFWISSSTYKDRNEEYRQQFTHLPDSEKLIADYACALQKDILVQGRLYLSEKWLCFYSNIFRWETTISIALKNITFMTKEKTARLIPNAIQIITEGEKFFFTSFGARDRSYLIIFRLWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMEHLLSVEENVQPRSPGRSSVDDAGERDEKFSKAVSFTQESVSRASETEPLDGNSPKRGLGKEDSQSERNVRKSPSLASEKRISRAPSKSLDLNKNEYLSLDKSSTSDSVDEENI... | [
18892,
25014,
25079,
27254,
30009,
35250,
39372,
46082,
60823,
77135,
87103,
87276,
87432,
87732,
87733,
87760,
88008,
88159,
88161,
88162
] | The following text describes a protein:
Function:
Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholestero... | 0 |
MIITPVSNEIISMVSQNKTLKFTEEVALQILLLCQSGVGTVGNVILFLHNFVLVLTDSQLKPNHVILSNFAVANIFILFLLTFTNTMAVWAPRKPPKNLTCKLTYFFYMVARSTNMCSTCALSIYQFVTLVPGNLTRVMLREISPKVMKYSCYSCWLFSVLNNAYIPMNVSGPQKTNNDTDPTGKWVCSISGFSVGMSFLRFVQDTIFISTMVWTTVSMVIHLNRHHQRICYIHNPSKDHRGYAETRAANTILMLVVTFVTFYLLDCICTFFHISFVDTRFWLRHVKEILTVSFPTISPLILIFRNPRGPCPVPFVVELQ... | [
8971,
10956,
25079,
29050,
30210,
39273,
50338,
87276,
87413,
87484,
87760,
87905,
88006,
88008,
88152,
88159,
88161
] | The following text describes a protein:
Function:
Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior.
Subcellular Localization:
Cell membrane; Multi-pass membrane protein. | 0 |
MAFKLWERFSQADNVFQALRPLTFISLLGLAPFRLNLNPRKEVQTSKFSFFAGIVHFLFFVLCFGISVKEGDSIIGYFFQTNITRFSDGTLRLTGILAMSTIFGFAMFKRQRLVSIIQNNIVVDEIFVRLGMKLDYRRILLSSFLISLGMLLFNVIYLCVSYSLLVSATISPSFVTFTTFALPHINISLMVFKFLCTTDLARSRFSMLNEILQDILDAHIEQLSALELSPMHSVVNHRRYSHRLRNLISTPMKRYSVTSVIRLNPEYAIKQVSNIHNLLCDICQTIEEYFTYPLLGIIAISFLFILFDDFYILEAILNPK... | [
8663,
8996,
9008,
12938,
16569,
25079,
25325,
25494,
25495,
26197,
29300,
29911,
47375,
87276,
87522,
87760,
88006,
88008,
88152,
88159,
88161
] | The following text describes a protein:
Function:
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression also suggests nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory... | 0 |
MASQAHSLSYSGCNFLRQRLVLSTLSGRPVKIRKIRARDDNPGLRDFEASFIRLLDKVTNGSRIEINQTGTTLYYQPGLLYGGSMEHDCSVLRGIGYYLESLLCLAPFMKHPLRIVLRGVTNDQVDPSVDVLKATALPLLKQFGIDGESFELKVVRRGMPPGGGGEVFFSCPVRKVLKPIQLIDPGKIKRIRGMAYSVRVSPQMANRIVDSARSILNKFIPDIYIYTDHMKGINSGKSPGFGLSLVAETTNGTFLSAELASNPQGQGAAMLPEDLGRNCARLLLEEIYRGGCVDSTNQSLALLLMTLGQQDVSKVLLGPL... | [
6768,
14135,
24974,
25726,
28403,
36129,
47537,
47538,
49452,
52882,
55540,
64296,
64840,
87857,
88008,
88023
] | The following text describes a protein:
Function:
As part of the small subunit (SSU) processome, it plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity). Activates BMS1 by promoting GDP/GTP e... | 0 |
MSQKSVVLHLYRSLVRESKKFSSYNFREYSLRRVSVGFRENKNKDQNETKELIQDALKNLEMVKRQAFINSMYSTNKLVVE | [
10680,
24917,
24979,
27459,
42776,
71507,
77175,
87785,
87857,
88008
] | The following text describes a protein:
Function:
Required for nuclear and mitochondrial iron-sulfur protein biosynthesis.
Subcellular Localization:
Mitochondrion. Nucleus. | 0 |
MVIKDLSPHNNSLRKKYLDLIDYGNKNPLTVDPNLYQLRKTILLEGLPPETEEEIEDRTKQDGSKCSLRGMIWKILLGVDKIQPDKYIELIEKGPSNRYQKIRKDIGRTFNRDSQFSQAVSQDQLSRCLNAFAHQCEELGYVQGMNAICGTFLYVLPEVEAFQCFYSLLTQCCPNYFTSNISGVNDASKLLDRILEFVDPELYEYLQNRSYHPLLFTPPILSLGTATPPLDELLKLWDFFLAFGFHLNVICTISQILLMRDVLLVHQSPCLLFRSFPELDAPTIINLSIHIIRQLPDDIYDLLVDHPMTSVDLTPFDRDP... | [
16787,
24978,
25031,
28816,
36101,
63765,
87272,
87273,
87367,
87371,
87790,
88008
] | The following text describes a protein:
Function:
Part of a checkpoint which monitors spindle integrity and prevents premature exit from mitosis.
Subcellular Localization:
Cytoplasm, cytoskeleton, spindle. | 0 |
MSLLLYYALPALGSYAMLSIFFLRRPHLLHTPRAPTFRIRLGAHRGGSGELLENTMEAMENSMAQRSDLLELDCQLTRDRVVVVSHDENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSPGHFAHGSDRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREIAGLVRRYDRNEITIWASEKSSVMKKCKAANPEMPLSFTISRGFWVLLSYYLGLLPFIPIPEKFFFCFLPNIINRTYFPFSCSCLNQLLAVVSKWLIMRKSLIRHLEERGVQVVFWCLNEESDFEAAFSVGATGVMTDYPTALRHYLDNHGPAARTS | [
13083,
15685,
18427,
25014,
26465,
28482,
29072,
32536,
50789,
59806,
77921,
87367,
87432,
87601,
87731,
87760,
87767,
88008,
88159,
88161
] | The following text describes a protein:
Function:
Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylcholine (lyso-PC) and N-acylethanolamine lysophospholipids. Does not display... | 0 |
MGLWRSWRRSRVRKSIRYFGIFPSRADVRYWDIEQQPLWKKCPTVSKRELPQTDLFREEAAHLFHAGEQKPDFAKPPVNEPRESEQFLMQAPPGNPLLLPHTLQELLSKDSVQVELIPEKKGLFLKHVEYEVSSKRFKCSVYRRYNDFVVFHEMLLQKFPYRMVPALPPKRMLGADREFIESRRRALKRFINLVARHPPFSEDVLLKLFLSFSGSDVQNKLRELVQGVGDEFLTCRLATQAKDFLPADIQAQFAASRELIRNIYNSFYKLRDRAERIASRAIDNASDLLIFGKELSALGSDTTPLPSWAALNNSTWGTLK... | [
8490,
13050,
25040,
25551,
25696,
31754,
32073,
37343,
58151,
59029,
63514,
64601,
71900,
87434,
87733,
87760,
87974,
87976,
88008,
88162
] | The following text describes a protein:
Function:
May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network.
Subcellular Localization:
Early endosome membrane; Peripheral membrane protein. Endosome membrane; Periphe... | 0 |
MITQPKPWFEASVLIPILVFFISGFLAPSSKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDLHRRVLRFRKNSSCSGPQAKGFSF | [
25560,
29104,
36302,
65925,
87760,
88008,
88157,
88159,
88161,
88162,
88178
] | The following text describes a protein:
Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate elec... | 0 |
MAKYYNEPCHTFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIALAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLAISQRTTHNTVAVTDDGTPHGVLLGLVTQRDYPIDLTQTETKVSDMMTPFSKLVTAHQDTKLSEANKIIWEKKLNALPIIDDDQHLRYIVFRKDYDRSQVCHNELVDSQKRYLVGAGINTRDFRERVPALVEAGADVLCIDSSDGFSEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGADFIKIGIGGGSICI... | [
88,
7994,
7999,
24978,
25807,
27656,
28031,
32073,
32536,
36470,
36847,
41009,
47531,
49018,
72392,
87012,
87103,
87237,
87367,
87488,
87767,
87822,
87873,
87945,
87981,
88009
] | The following text describes a protein:
Function:
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a... | 0 |
MSQAFICETGFCPRCGSIMPSPSSAQTINCIVCNNQISIDSYLGVETKSTITFNAIRSKGVQKIKDDTQHAKGPIIERKCEKCGNNSMTYYTQQTRSADEGQTVFYSCTKCGIISVLFAL | [
8108,
24977,
27903,
28007,
29166,
36956,
46190,
62200,
87386,
87767,
87857,
88008,
88148,
88261,
88263
] | The following text describes a protein:
Function:
Core component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Can mediate Pol I proofreading of the nascent RNA transcript. Anchors into the Pol I active s... | 0 |
MAKNKKRRSLTSKVEQRSKATEIKNNPFEVKINKQKHNILGRKNKHGKGVPVVSRSKGLQKRNATLLQEYKQRHKSNKFLDKRLGENDPEMSVEDKMMERFTLEKQRNHEKSGMYSLNTDEDLTHYGQSLSSLEKFEEPDLASDDEEGGMIDKKFVAEEHFGGFLTKKKTDEEGKPKTRQEIFEEIIAKSKKDKFNRQSEKEDVVKLTEQLDQDFNDVSQFLAKVKRDKDEERRKPDDYDMSVKELIFDMRAKASDRLKTPEELAKEEKEKLEKMETDRQRRMKGITETEEQENKRRMQYLSADDLNDGFELTRDNRSTL... | [
11740,
24974,
25530,
25726,
42129,
87857,
88008,
88023,
88276
] | The following text describes a protein:
Function:
Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
Subcellular Localization:
Nucleus, nucleolus. | 0 |
MVMASGRQAALVGGRLLQRQPLNAALKTQTRSFYTIFEKYLEANKRYGWKGTLWKLYNPGDVKFGRLVGEDENGFKYYEDPTEVYGQHRWTEYQVDSWDEVEGTLIPPQWHLWMHHLTDSLPGEGGQDPANWEKEETCSHSDAPYANHLGDHVPYYPNKTLYRSRGYNVGSLATKADEPDQYYLQPGHLRRTRKRQPHYFADVDYNNPDQSDESRAQSLRPADIN | [
24983,
26427,
42564,
87425,
87760,
87785,
87786,
88008,
88011,
88162
] | The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for t... | 0 |
MPAMNLKYKFGLVNSAGRYLTAEKFGGKVNASGATLKARQVWILEQEESSTISYLKAPSGNFLSADKNGNVYCSVEDRTEDADTGFEIELQPDGKWALKNVSHQRYLACNGEELICSESSTSNPSANWTVQLAIHPQVCMKNVQHQRYAHLKTSEEGEDSVVVDELVPWGADSTLTLVYLGKGKYGLEAFNGKFVQTDGQLAGTANEQTQFTLIFTSGHLVLRDNNGRHLGVDSGTRVLKSSKPGLTKANYFILEDSCPQGAFEFGGKYASLKQGEDVSFKLLVDEDIEDTETFQLEFVETDKYAIRVCDPKKNSRDAKF... | [
8661,
10729,
11593,
16631,
24978,
25314,
27940,
31013,
33717,
43580,
44811,
54695,
56311,
87118,
87367,
87371,
88008
] | The following text describes a protein:
Function:
Acts as an actin bundling protein.
Subcellular Localization:
Cytoplasm, cytoskeleton. | 0 |
MAENPGLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFINPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQ... | [
8286,
24926,
25040,
26145,
34098,
36127,
38132,
46078,
49116,
56465,
61175,
64697,
87115,
87367,
87857,
87914,
87974,
88008,
88009,
88162
] | The following text describes a protein:
Function:
Functions in nuclear protein import.
Subcellular Localization:
Cytoplasm. Nucleus. | 0 |
MALRKRSPHGLGFLCCFGGSDLPEIDLRDSHPLQYLEFSGPIPNPEELNVRFAELVDELDLTDKNREAVFALPPEKKWQIYCSKRKEQEDPNKLATSWPEYYIDRINAMAAMQNLYETEDEETDKRNQVVEDLKTALRTQPMRFVTRFIDLEGLTCLLNFLRGMDHTTCESRIHTSLIGCIKALMNNSQGRAHVLAQPEAISIIAQSLRTENSKTKVAVLEILGAVCLVPGGHKKVLQAMLHYQAYAAERTRFQTLLNELDRSLGRYRDEVNLKTAIMSFINAVLNAGAGEDNLEFRLHLRYEFLMLGIQPVIDKLRQHE... | [
8802,
10615,
11263,
11593,
11711,
11822,
16294,
16867,
17782,
19821,
19971,
24025,
27940,
31103,
44845,
44846,
46078,
48283,
48284,
48884,
49116,
69183,
77078,
87139,
87326,
88008,
88256
] | The following text describes a protein:
Function:
Key regulator of the Wnt signaling pathway, which is required for various processes during development, such as dorsal patterning, determination of left/right symmetry or myelination in the central nervous system. Acts downstream of Wnt ligands and upstream of beta-cate... | 0 |
MSAQSLPAATPPTLKPPRIIRPRPPSRHRAPHSPGPLHNGSSPKALPQISNDASASVCTSIFWEPPTASLKPPALLPPSVSRTSLDSQTSPDSPSSTPSPSPVSRRSISPEPAPCSPVPPPKPSGSSRTPLPSGPTPLQDGSASAPGTVRRLAGKFEWGAEGKAQSSDSLERCSQGSTEVNGEKETPEAALSGNGSQENGTPDAALACPPCCPCVCHVAKPGLELRWVPVGSSEDILRIPCRASPLRASRSRINPPVISHPPVVLTSYRSTAERKLLPPLKPPKPTKVRQDISTSEELPQPDLKLPSEDGIQTATKAWEG... | [
16874,
18012,
21112,
24178,
24978,
25495,
27051,
27093,
28810,
28816,
36123,
46082,
63700,
73239,
73240,
87139,
87278,
87492,
87535,
87914,
88008,
88180
] | The following text describes a protein:
Function:
Specific GEF for RhoA activation. Does not activate RAC1 or CDC42. Regulates vascular smooth muscle contractility. Negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2.
Miscellaneous:
MISCELLANEOUS: In a mouse model ... | 0 |
MLKTLLFILIFFNIPIIAIEEIPDIKENGEKSSYTQFDNGAKLEVNKEHKRVIKIGHIGAVGVMPNDARILNISKENLIEEGLVGDDIEFEIVSRQACSESFEGVAVAAELYHVHQVRAFIGPYCAAELEAVTKMATFWNIPIISYSSVPNAVSDRSVYKTLARVSSKNTNSIAEATVALLLHYKWLKVAIATNTGSTAFERVSIFEEIMHREGVTIVKKVMFDENTDANEMMNSGQLGDLAANARIIICLFSSTKELSKEFMQATYTMRMNNAEYAYIIPWLQSGTKDLTPWIGADGEMLQRVKDHYANAIIVDDVNGF... | [
5944,
7998,
8666,
10608,
13402,
14032,
14466,
25079,
25108,
25678,
26355,
27831,
28296,
28522,
29033,
29034,
32536,
36535,
36815,
36977,
37459,
45290,
51057,
58725,
59723,
76056,
87276,
87278,
87326,
87491,
87522,
87741,
87747,
87760,
87767,
8785... | The following text describes a protein:
Function:
Guanylate cyclase involved in the production of the second messenger cGMP (By similarity). Regulates thermotaxis responses in AFD sensory neurons. May regulate AFD neuronal activity such as calcium responses to temperature gradients.
Subcellular Localization:
Cell membr... | 0 |
MWPPNAENNHCNYSYHEHAELNPHDHYHHHHYPHSSVHHTECYQTLSCPSDLPVETSYYNSVPPSYQDLGQTDLSPQFWCAEVDCVHERCSTKEIPHEQSKIFEEISKECDHIMNSAGDCEKCQVEHENGAQEAIPINDLVDIVMQTVDNLKKEGSSNDETKLLSRKRQQNKVAAARYRDKQKAKWQDLLDQLEAEEDRNQRLKLQAGHLEKEVAEMRQAFLAKLAKK | [
8103,
16514,
24917,
27733,
27735,
35342,
39958,
72396,
87384,
87857,
88008,
88148,
88150
] | The following text describes a protein:
Function:
Transcription factor (By similarity). Involved in modulating innate immune response pathways, acting to promote resistance against infection by Gram-negative bacterium P.aeruginosa strain PA14. May act as part of a feedback regulatory loop with the pmk-1/p38 MAPK pathwa... | 0 |
MYWFRQVYRPSFFFGFLAILLLSSPTPSDASIRLCGSRLTTTLLAVCRNQLCTGLTAFKRSADQSYAPTTRDLFHIHHQQKRGGIATECCEKRCSFAYLKTFCCNQDDN | [
8973,
15754,
16580,
23715,
24878,
25636,
26195,
26197,
26413,
28880,
49228,
54320,
54321,
64193,
87317,
87413,
88008,
88038,
88058
] | The following text describes a protein:
Function:
May have a role in gut contractility or in thymic development and regulation. Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor.
Subcellular Localization:
Secreted. | 0 |
MSNRPESSISMEFREFYCVGDTPKKEEDPTDINSSIFNAKLLFDKSTKTLSIHQLVAQEISLVADIESLDNDMQTLVYDNYTKFLNASDLVITFGDNISVLESQVSDLSNTLTKVASHNENISSGLHENREKIQRLIGIQRLLERIKFISRLPSILKSNLQKKNFNTAVKIWIKVEKILRTQQRFPSFSQIYEESTEIMKEIKNKITEQMLTSDITVENSVNDGVLLVQLGTSLILICSQLIHHQFLIVDNAIDEIELEDEPFTALSHLNESIIDHTSKFITLYKYNLIPLSPDEETKTKAETILTGFANKFFERILPIL... | [
8478,
8582,
8592,
10368,
12331,
14087,
15997,
24822,
25040,
25325,
27587,
48323,
87528,
87732,
87974,
88008,
88162
] | The following text describes a protein:
Function:
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).
Subcellular Localization:
Golgi apparatus, trans-Golgi network. | 0 |
MSVLTVPRQTPRQRLPVLPCHVGDPDLWFADTPAGLEVAKTLCVSCPIRRQCLAAALQRAEPWGVWGGEIFDQGSIVSHKRPRGRPRKDAVA | [
15142,
15387,
15790,
18536,
24978,
27904,
31845,
32536,
33780,
38778,
50797,
62798,
87042,
87103,
87105,
87160,
87367,
87384,
87413,
87678,
87681,
87767,
88008,
88148,
88150
] | The following text describes a protein:
Function:
The apo- but not holo-form probably binds DNA (By similarity). Acts as a transcriptional regulator. Probably redox-responsive. Upon overproduction at least 10 other genes are up-regulated, among them are Rv1258c, Rv1988, Rv2301, Rv2416c, Rv2725c and whiB7 itself. Probab... | 0 |
MNPPADETATGTSTPTSSSTPRRPGKRTAEEMALDLINNRPKVKRIVKLVSVFYEGKMLELDLNETTVPRGLIQWLRHLCSLIDEVTEGGFPKEWKVDDDPKNVLGPYTHDELVELVDMYNLVAKPFAGAWAGSYNTGNLGDWGNPHCTSEIAGSIVQLAIEMGIPKVEDLNNCYRAWSSENHILELISMTPMRLSMPPMRHVKKSSIMLFQVYGETNLNQMASILDEVGVTNKDVFIDLGCGIGQLVFFTAAYAQCKKSYGIELNPFPYQLGANVQSIFTKLMKNFGKRFGKNEILEGDLMNVVFRAKISEATVIFINN... | [
2330,
6663,
8065,
12059,
12244,
24785,
24917,
25993,
31091,
35578,
57223,
59229,
59818,
87302,
87777,
87857,
88008,
88026,
88153
] | The following text describes a protein:
Function:
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleos... | 0 |
MGVEIETISPGDGRTFPKKGQICVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGTAQMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLSLE | [
6065,
7143,
8525,
8693,
9439,
9882,
10143,
10144,
10950,
11193,
11606,
13509,
14063,
16522,
16729,
16771,
16995,
17987,
25353,
25443,
25818,
25963,
27936,
28817,
29036,
30796,
32344,
36918,
72405,
76344,
87367,
87683,
88008,
88024,
88035
] | The following text describes a protein:
Function:
Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
Subcellular Localiza... | 0 |
MAESKRSVDRLRAPVVCVLGHVDTGKTKILDKLRRTNVQDGEAGGITQQIGATNVPHEALMQQTKMCKDLQVKIPGLLIIDTPGHESFSNLRTRGSSLCDIAILVVDIMHGLEPQTIESINILKQRKTPFVVALNKIDRLFGWITNPHSDVTNLLKKQKQNTKLEFDERTSHVIVQFAEQGLNARLFYENKNPREYISLVPTSAMTGDGIGNLITLICELTQTLLVKRLTFTEELQATVMEVKAIPGHGTTIDVILVNGRLKTGSTIIVAGQDGPIVTQIRSLLMPQPMHELRVKSQFESHKEVLAAQGCKIAAKDLEKA... | [
5186,
8139,
24978,
27933,
28025,
29034,
32536,
36600,
40315,
43581,
48958,
54970,
58239,
59609,
64653,
87055,
87367,
87491,
87601,
87661,
87767,
87855,
87968,
88008
] | The following text describes a protein:
Function:
Plays a role in translation initiation. Ribosome-dependent GTPase that promotes the joining of the 60S ribosomal subunit to the pre-initiation complex to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon. Tog... | 0 |
MPGKLKVKIVAGRHLPVMDRASDLTDAFVEVKFGNTTFKTDVYLKSLNPQWNSEWFKFEVDDEDLQDEPLQITVLDHDTYSANDAIGKVYIDIDPLLYSEAATVISGWFPIYDTIHGIRGEINVVVKVDLFNDLNRFRQSSCGVKFFCTTSIPKCYRAVVIHGFVEELVVNEDPEYQWIDRIRTPRASNEARQRLISLMSGELQRKIGLKVLEMRGNAVVGYLQCFDLEGESGLVVRAIGTACTLDKLSSPAAFLPACNSPSKEMKEIPFNEDPNPNTHSSGPSTPLKNQTYSFSPSKSYSRQSSSSDTDLSLTPKTGMG... | [
8505,
9053,
10116,
12010,
15612,
18307,
19410,
19864,
25079,
25114,
25510,
25786,
29025,
29044,
35959,
63695,
65376,
66419,
87244,
87276,
87278,
87367,
87369,
87733,
87760,
87767,
87974,
88162
] | The following text describes a protein:
Function:
Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary f... | 0 |
MSSNECFKCGRSGHWARECPTGGGRGRGMRSRGRGGFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDEACYNCGRGGHIAKDCKEPKREREQCCYNCGKPGHLARDCDHADEQKCYSCGEFGHIQKDCTKVKCYRCGETGHVAINCSKTSEVNCYRCGESGHLARECTIEATA | [
6673,
9051,
15388,
15427,
19140,
24917,
25008,
25040,
29166,
33827,
37501,
64605,
87115,
87139,
87367,
87384,
87432,
87767,
87776,
87857,
87914,
88008,
88009,
88010,
88148,
88150,
88261,
88263
] | The following text describes a protein:
Function:
Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (By similarity). Has a role as transactivator of the Myc promoter. Binds single-stranded RNA in ... | 0 |
MALVPYEETTEFGLQKFHKPLKTFSFANHTIQIRQDWRHLGVAAVVWDAAIVLSTYLEMGAVELRGRSAVELGAGTGLVGIVAALLALKSSMKPLLVHCLLFFSGAHVTITDRKVALEFLKSNVQANLPPHIQPKTVVKELTWGQNLGSFSPGEFDLILGADIIYLEETFTDLLQTLEHLCSNHSVILLACRIRYERDNNFLAMLERQFTVRKVHYDPEKDVHIYEAQKRNQKEDL | [
2070,
8184,
25040,
25807,
30153,
30977,
33735,
51955,
59229,
87367,
87777,
88008,
88026,
88153
] | The following text describes a protein:
Function:
Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys-564' in HSPA2, 'Lys-585' ... | 0 |
MGIGDLRSWTSVVVVILTLISMVSSSGFFELQILEISNTNSHLLSGYCCGLPPEKRQTQTTGCPACATAFSLCLKEYQGTTSSVQQQQQQLKQPAVAVEPQPSGLYGCAFGNASTPVLGGSSFVLTDPEVGGITLPFTFRWTKSFTLILQALDMYNESYSISERLIDETSFSGVILPSHDWNTLDHIGKSARITYRVRVQCADNYYNTTCTTFCRPRNDQFGHYTCGKQGNKVCMPGWQGANCEKAICKPGCDQIHGKCDQPGECECRPGWRGPLCNECMVYPGCRHGYCNGSAWQCICDTNWGGILCDQDLNYCGTHEP... | [
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10708,
11608,
11809,
11838,
13251,
13267,
13635,
14003,
14051,
15617,
15943,
15967,
16239,
16299,
16381,
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25094,
25278,
26411,
28822,
29025,
30814,
32146,
33211,
36067,
36552,
36778,
37419,
37503... | The following text describes a protein:
Function:
Putative Notch ligand involved in the mediation of Notch signaling.
Subcellular Localization:
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. | 0 |
MALAQTEEIARRLTAAVPGLDVEIVKFDTTGDLDQTSKLLPHGGKGGAFVAQIRAAVLSGELQAAMHSLKDMPGNEDTPGLVIGATLSRDPPSDALVLRDGVTLEALRQSRGKGFKIGTNAVRRAAYARRLFPDVEVIHFRGAADTRVRKLDNGEKQRLPDGGAVGPADALIMARSGLDRVGLASRIAYEFTPAEMLPAAGQGIVAVECAAQDWQTRKILSSIDDPAAHACADAEREVLWVLNGHCNSPVAGFSTIAGDQMSLTASVLDLSGNTIIEASRTGSANRPRELGRAVGLELLGKGAAEIIERSRPR | [
3260,
8420,
8421,
24978,
28319,
36658,
54378,
54379,
54380,
64537,
87073,
87942,
88008,
88153
] | The following text describes a protein:
Function:
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. | 0 |
MECPHLSSSVCIAPDSAKFPNGSPSSWCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYRCDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAICATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQN... | [
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26819,
28657,
29166,
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35572,
37104,
37278,
46929,
50970,
59082,
66234,
75840,
87115,
87139,
87272,
87302,
87367,
87374,
87601,
87767,
87857,
87965,
87976,
88008,
8813... | The following text describes a protein:
Function:
Deubiquitinase that plays a role in several cellular processes including transcriptional regulation, cell cycle progression or innate immunity. In response to DNA damage, deubiquitinates monoubiquitinated target proteins such as histone H2A and H2AX and thereby countera... | 0 |
MPVRVSEFSWQQTPATIFLSLPLRGVCVRDADVFCGESYLKVNFPPFLFELFLYAPIDDGKSKAKIGNDTILFTLYKKEPVLWDSLSVPGVDKEMMQRIREKSILQAQEKAKEATEAKAVAKREDQRYALGEMMKIEEEERKKIEDMKENERKKATSELEAWKECQKKADGQKRVQRKEKPLEGKQAEETKALKPRGLPRKAPPTRLPTRGRNWENIFPEKLKEDRVPAPRSAGSIQISFTPRVFPTALRESQVAEEEEWLHKQAEARRAMSTDLPEFFDLKEEERNPDWLKDKGNKLFATENYLAAVDAYNLAIRLNCK... | [
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7797,
7804,
8802,
8912,
8973,
12655,
13695,
13696,
16949,
17964,
24878,
24917,
24978,
25026,
25040,
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26990,
27234,
30937,
41945,
43562,
46079,
52236,
65465,
77656,
87278,
87367,
87829,
87857,
88008,
88009,
88114
] | The following text describes a protein:
Function:
Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity (By similarity). Axonemal dynei... | 0 |
MAEAEARPAEPAGWAKALMSVCSLMFGVSAWVSINGLWVQMPLLVPRLPEGWNLGSILVIVIQVANLGPLAYTLARKRRVGVVQVKAAVHATLFVGLTAGVLLVFLWQETVGGHSVAFIALAFFLSMVDCTSSVLYMPFMARYPQQFLFWYMVGEGLSGLVPAGLALAQGVDNKADNETTNATHGNATHAGGTVGPRFSIEVFLSLLCVIVAISWAAFSVLAHLPALKKEPSLKYGSNDNRGYVPEDGTDHVVPQVLEQPNGLERAGPSNDPGKGDDLMKRWQWNLALAMQSTIAALSNGVLLAVQTYSSLPYGQLPYHL... | [
12222,
25079,
31301,
43867,
87276,
87760,
88006,
88008,
88159,
88161,
88162
] | The following text describes a protein:
Function:
Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.
Subcellular Localization:
Cell membrane; Multi-... | 0 |
MSRRKQAKPQQLRSDEDPTLLELLPEHVSGEGVDDSDSGNESRSGSEETHVCEKCCAEFFKWSDFCEHLKTCTKNPLVLIISDNEVTSDPAQDYLPEPSPVPSCVSDPANSEDAVEVSHMPTEGDEGAEMMLESGAVLEKEDEPMEVELSPEKPIDPDDPVTLAEPDISLPPLEDHKQSSGAGYSIPSTNVTLETLHGTRVAVAQFSQGARGALASEVSTMAIPMILDQLMALQQQQLRQLKLIEQIRSQVALINNQAPTQTAVSHKVDHSINAALQVPSSSSIPAMPGQLHLRGFITPPINQLHMNNSLNVQASVAVSS... | [
6673,
7793,
8103,
8912,
9575,
11409,
13298,
15427,
24791,
24917,
24926,
27735,
27904,
29166,
46932,
64003,
77218,
87384,
87684,
87767,
87857,
87914,
88008,
88009,
88010,
88148,
88150,
88180,
88261,
88263
] | The following text describes a protein:
Function:
Probable transcription factor; Transcriptional repressor involved in organogenesis. Plays an essential role in ureteric bud invasion during kidney development.
Subcellular Localization:
Nucleus. | 0 |
MAAAQPPRNATRVIEVLRNFLAGREIKPNLRYQDFIVKRSGPPPKLPSGPAHRLNKNYYYTRDLRREARPPVEISKQALLPASSEIKRAETESVKTVVPGQPVNWSENPY | [
7966,
24983,
26427,
44373,
87115,
87425,
87760,
87785,
87786,
88008,
88011,
88162
] | The following text describes a protein:
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for t... | 0 |
XSDEEDEERPARKRRQVERATEDGEEDEEMIESIENLEDLKGHSVREWVSMAGPRLEIHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQIFDEAALEVVLAMYPKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSCTGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNTANGFPVFATVILANHVAKKDNKVAVGELT... | [
5173,
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24741,
24926,
25040,
25108,
26144,
27904,
28298,
29033,
29166,
30398,
32042,
36945,
42806,
46277,
51196,
58239,
58587,
60237,
62000,
68595,
87110,
87272,
87306,
87381,
87384,
87539,
87601,
87767,
87855,
87857,
87976,
88008,
88261,
882... | The following text describes a protein:
Function:
Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwin... | 0 |
MNRLTTDQKQKCVDFMSITQSNEIKAIQYLRDAGWNPENAIDRYYSNPANITEPRLDKKAIEALFKKYKDDEDSISENLVNLIKDVNISEEFMEFAFLWKFKAKQMDSISKNEFIDAMEKTIKCDSLKSLGNYFVQVKQQLLSPEPNNPHFKEYYQYIYDLGKATNQKNVSLQMCIELWTIVLKPKFADIQIWFDFLNSNHKLAISKDTWNLFLDFIRIANDDISKYDSDGAWPVLIDEFVDYYRTHKK | [
15057,
24729,
31138,
31296,
34681,
40271,
43625,
48282,
69371,
88008,
88181
] | The following text describes a protein:
Function:
Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. | 0 |
MAGIKALISLSFGGAIGLMFLMLGCALPIYNQYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGIVVSAFGLPIVFARAHLRPNVCIRDVSVLTRALPKLRSKARCTQEGVIQDPVGVVVWVTTLLPGNS | [
12372,
17507,
24996,
25325,
42116,
87760,
88008,
88159,
88161
] | The following text describes a protein:
Function:
Negatively regulates growth hormone (GH) receptor cell surface expression in liver. May play a role in liver resistance to GH during periods of reduced nutrient availability.
Subcellular Localization:
Membrane; Multi-pass membrane protein. | 0 |
MTALTEYERKRLENIKKNQSLLSSLAIKSVGPAAKKGSKRPAPSSSTPSKKRGRPATGTDSPLPPKRHATRASVRLSGVGLDPVELQSRLEKEEQELASERQKREELKHSDRPLVAESLRTGPSSSLTSNLFSSLAHTIAVKPIKTMKEEEVNLEYSPGDDEDYDRLAGELKGLQLRSLNKVCPNRIYSMNFHPDPSKSLLFMGEKLGGVGIWDALGEQPAVKSEDVEDEDHVSTTSTNTADVSSKPSVSPAKPVKQEEEDDDEEDRPEFVEGVSYFIQAHARYSAVSAIQAHPSNPHLVCTSSYDRTIRELNFESQQST... | [
8549,
23981,
24917,
27904,
37341,
49061,
52270,
64085,
76508,
87374,
87384,
88008,
88009,
88252
] | The following text describes a protein:
Function:
DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. | 0 |
MAKRKRRSRAAEEDVEPAEKEEVLPPISRKSDEPPQKKTKWINKQRVMIFASRGITFRDRHLMLNLRTMLPHSKPESKMEKKDPLVVINEAFNENPYTKLLKELLCQVFGTPRHHPKSQPFVDHVFTFSLLDHRIWFRNYQIVEEEGSLVEIGPRFVLNPIKVFEGSFGGPVIYSNPHYITPSAYRRTLKQAAASKYKGRKEAKANLKHRIAEGPAPSNPIDEIFETIPPEKAKGKDKLLFQRKKQ | [
6648,
8109,
24974,
27925,
30795,
41978,
57824,
87857,
87976,
88008,
88023
] | The following text describes a protein:
Function:
Required for biogenesis of the 60S ribosomal subunit.
Subcellular Localization:
Nucleus, nucleolus. | 0 |
MSDVTRHGSTFVWGYGSDNGPSKWGQYYPICLGKRQSPINIDSLRTTFNPKLEHIQASHYISPQPNIKTTLTNIGKSIFIQPAIDYSPVLVDPLNSGVFYRAHHLHFHWGASDNYGSENAIDNKYYPIEIHIVHYNIKYQNVLQAIPKPDGLAVIGIFAKIGEGSAGFSWLLQYMQKLQYKDETVTANGFSYSSFLPKDMSKYFTFPGSLTTPLCEESVRWIVMEEPITISSQQSSFNLILHV | [
5443,
24978,
28145,
29166,
36893,
51092,
55335,
64156,
87039,
87741,
87767,
88008,
88261
] | The following text describes a protein:
Function:
Reversible hydration of carbon dioxide. | 0 |
MSRHFRTHTTSRLTFPSSSGGLAITRLPFSSTSSKLLLQQLSSTSPAAAATAVTITTSSPARNLQRARASAAEQGMEEHGKAAVGWAARDDSGVLSPYNFSRRAQKDDDVTIKVLYCGICHTDLHVVKNDWGNAMYPVVPGHEIVGVVTGVGAGVTKFKAGDTVGVGFFVGSCRTCDSCGKGYENYCPTMVITSNGKDYGGAATQGGFSDAIVVNEHYVLRVPAGLPLDGAAPLLCAGVTVYSPMVIHGLNAPGKHVGVVGLGGLGHVAVKFAKAFGMRVTVISTSPGKRREALEHLGADEFLVSRDAGQMAAAAGTMDG... | [
77,
9474,
29166,
32455,
33419,
37878,
45309,
46979,
46984,
52938,
64058,
73085,
87039,
87724,
87767,
87823,
87873,
88008,
88261
] | The following text describes a protein:
Function:
Involved in lignin biosynthesis. Catalyzes the final step specific for the production of lignin monomers. Catalyzes the NADPH-dependent reduction of coniferaldehyde, 5-hydroxyconiferaldehyde, sinapaldehyde, 4-coumaraldehyde and caffeyl aldehyde to their respective alcoh... | 0 |
MREQRSFSSASQPHLEHAYTPVSGKPLPPKGLAVARATGIQYGGWILTLPSQGPLRRSSSRKPPLERRRPLPQSPLFFSARGDQGLTASSAFRMKNYKAIGKIGEGTFSEVLKMQSLRDGNYYACKQMKQHFESIEQVNNLREIQALRRLNPHPNILTLHEVVFDRKSGSLALICELMDMNIYELIRGRRHPLSEKKIMHYMYQLCKSLDHMHRNGIFHRDVKPENILVKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYTYKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPCQKTLT... | [
3618,
13402,
24917,
24978,
25108,
26957,
28524,
29033,
32536,
36535,
42974,
45290,
50333,
75772,
87016,
87110,
87278,
87367,
87694,
87747,
87767,
87855,
87857,
87914,
88008,
88052,
88153
] | The following text describes a protein:
Function:
Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.
Subcellular Localization:
Cell projection, cilium. Cytoplasm. Nucleus. | 0 |
MSKVIHVTSNEELDKYLQHQRVVVDFSAEWCGPCRAIAPVFDKLSNEFTTFTFVHVDIDKVNTHPIVKEIRSVPTFYFYVNGAKVSEFSGANEATLRSTLEANI | [
25571,
27937,
29759,
29760,
40786,
47521,
50781,
64016,
87413,
87425,
88007,
88008,
88162
] | The following text describes a protein:
Function:
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. | 0 |
MMKVLGFLVLLALSSALTCEAAIFKPISHSHRSAALELFTPADGSFKSFEEAYEALRTFEVLGIKKQPDQRADTCASVVDTLSSPSSALKDLFQALRVNGLLNCELNKKAFAGIVPRLKDAVKIASSLLDSYYSVGSLVLIKGLSSDVDVHLESADSVFRAIKALGQSDGRWRYSSNNPESSTYAAGIAFESLAGVISLASSEIDQSLISMVKNDISKLLGGLEKYDDGAYYFDEKLVDAQGHQGPLAASSAVVCGITSFATVSAENLNLPGDKILGLARFFLGIGVPGNAKDLYYQVEALASLENNRVSMPLILSLPTN... | [
8189,
25147,
43429,
87432,
87760,
88008,
88058,
88159,
88161
] | The following text describes a protein:
Function:
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascen... | 0 |
MTDAGSWCLIESDPGVFTEMLRGFGVDGLQVEELYSLDDDKAMTRPTYGLIFLFKWRQGDETTGIPSDKQNIFFAHQTIQNACATQALINLLMNVEDTDVKLGNILNQYKEFAIDLDPNTRGHCLSNSEEIRTVHNSFSRQTLFELDIKGGESEDNYHFVTYVPIGNKVYELDGLRELPLEVAEFQKEQDWIEAIKPVIQQRMQKYSEGEITFNLMALVPNRKQKLQEMMENLIQANENNELEEQIADLNKAIADEDYKMEMYRKENNRRRHNYTPFVIELMKILAKEGKLVGLVDNAYQAAKEKSKLNTDITKLELKRK... | [
4562,
8202,
10754,
12325,
12618,
24978,
28657,
37255,
50289,
64682,
66234,
68545,
87601,
87965,
88008,
88134,
88181
] | The following text describes a protein:
Function:
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. | 0 |
MNNDDIILAEMRPKKRAGRRVFKETRHPVYRGIRRRNGDKWVCEVREPTHQRRIWLGTYPTADMAARAHDVAVLALRGRSACLNFADSAWRLPVPESNDPDVIRRVAAEAAEMFRPVDLESGITVLPCAGDDVDLGFGSGSGSGSGSEERNSSSYGFGDYEEVSTTMMRLAEGPLMSPPRSYMEDMTPTNVYTEEEMCYEDMSLWSYRY | [
9295,
9300,
9828,
11208,
16144,
16513,
16878,
24917,
27731,
27918,
32185,
37168,
49227,
64679,
71487,
87123,
87384,
87857,
88008,
88086,
88148,
88150
] | The following text describes a protein:
Function:
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates cold or dehydration-inducible transcription. CBF/DREB1 factors play a key role in freezing tolerance and cold acclimation.
Subcellular Loc... | 0 |
MAETEALSKLREDFRMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQEVVDFEKLDDYASAFQGHDVGFCCLGTTRGKAGAEGFVRVDRDYVLKSAELAKAGGCKHFNLLSSKGADKSSKFLYLQVKGEVEAKVEELKFDRYSVFRPGVLLCDRQESRPGEWLVRKFFGSLPESWASGHSVPVVTVVRAMLNNVVRPRDKQMELLENKAIHDLGKAHGSLKP | [
6890,
8512,
11620,
14480,
15427,
16719,
24918,
24978,
25040,
28524,
30200,
49127,
64058,
87115,
87367,
87413,
87823,
88008,
88155,
88172
] | The following text describes a protein:
Function:
Represses translation by preventing reactivation of elongation factor eEF1A (By similarity). May also inhibit nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. Has additionally been proposed to act as a re... | 0 |
MSAEKSDKAKISAQIKHVPKDAQVIMSILKELNVQEYEPRVVNQLLEFTFRYVTCILDDAKVYANHARKKTIDLDDVRLATEVTLDKSFTGPLERHVLAKVADVRNSMPLPPIKPHCGLRLPPDRYCLTGVNYKLRATNQPKKMTKSAVEGRPLKTVVKPVSSANGPKRPHSVVAKQQVVTIPKPVIKFTTTTTTKTVGSSGGSGGGGGQEVKSESTGAGGDLKMEVDSDAAAVGSIAGASGSGAGSASGGGGGGGSSGVGVAVKREREEEEFEFVTN | [
8110,
8111,
11801,
16684,
24716,
24917,
24938,
27786,
27922,
32577,
38531,
43635,
77084,
87103,
87857,
88008,
88148,
88150
] | The following text describes a protein:
Function:
TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors.
Subcellular Localization:
Nucleus.
Domain:
The C-terminus is important for mediating interaction with e(y)2. | 0 |
MRWEFLPCLLLLISNNKIFGFKVPSINFEMLKDEGFEVSIPDEPGIQRVFYMFQIDDTCPALMDYITEAVNGSWVSKQKMSLQNNDKLQISMLVQFNEEIFEKSETRVIINTRLLTTKDSSSRGITFLTGEGECQAYLAPAQQAKRCKAAQTIVSNGRHTCQGELIFEDNFSEAQLNKTTWKHDIRQRMYHVEEELVAFDDAARNCFVKEGELHIVPTIATEVTDGSFKLGDRCTAVESPEQECNIAHGIFYSIKPPVFSAQIHTRNSFSFKFGKIVVRAKLPKGDWLFPYLMLQPVSTYAETHYAKQLRIAYARGNANL... | [
7241,
7514,
7854,
15044,
15045,
24878,
27794,
27863,
31981,
36566,
47128,
60632,
63609,
69736,
76201,
87139,
87522,
87616,
87662,
88008,
88038,
88058
] | The following text describes a protein:
Function:
Involved in the recognition of invading microorganisms. Binds specifically to beta-1,3-glucan and activates the phenoloxidase cascade (By similarity).
Subcellular Localization:
Secreted. | 0 |
MEPIPPSNGNKNNSMDKQPQQPQQPQQQQQQQQQQRRDQRNSKLNELNETERVRNRFISHEFHKLDRTKSRIDAPKISFSDSESESDSEFFLAKRNTNNNNQNNTSPTFSSANGKQSNLTQRKINTQIQSKQPTNNNVQPLTDDEGTINHSNHHHHHHNQNNNGNNNNNNNNNNNNNKISTPPKQEEKMTMNGLFTLRPSILSSESNGSSYRGFLNLLLILLITASFRLVILNHLLYGIRINLDLYKISEYHRWPGVMISLMINLFIIAAYLIEKAAAKQLLPDRICYLLRIINCAAVIIVPSGSIIAFSPNPASGIIVM... | [
2543,
2696,
7926,
8311,
9107,
11064,
20841,
25014,
28192,
33410,
39478,
48055,
87125,
87432,
87516,
87728,
87731,
87760,
88008,
88153,
88159,
88161
] | The following text describes a protein:
Function:
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.
Subcellular Localization:
Endoplasmic reticulum membrane; Multi-pass membrane protein. | 0 |
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