smiles
stringlengths
4
580
activity
stringclasses
3 values
HIV_active
int64
0
1
Cc1nc2ccc(Br)cc2c(=O)n1-c1ccc(N)cc1
CI
0
Cc1nc2c(Br)cc(Br)cc2c(=O)n1-c1ccccc1N
CI
0
NCCSc1nc2ccccc2c(=O)n1-c1ccccc1
CI
0
CC(=O)C(=NNc1ccc(-n2c(C)nc3ccccc3c2=O)cc1)C(C)=O
CI
0
CC(=O)C(=NNc1ccc(-n2c(C)nc3ccc(Br)cc3c2=O)cc1)C(C)=O
CI
0
CCOC(=O)C(=NNc1ccc(-n2c(C)nc3ccccc3c2=O)cc1)C(C)=O
CI
0
CCOC(=O)C(=NNc1ccc(-n2c(C)nc3ccc(Br)cc3c2=O)cc1)C(C)=O
CI
0
CCOC(=O)C(C#N)=NNc1ccc(-n2c(C)nc3ccccc3c2=O)cc1
CI
0
CCOC(=O)C(C#N)=NNc1ccc(-n2c(C)nc3ccc(Br)cc3c2=O)cc1
CI
0
CCOc1ccc(NC(=O)C(=Cc2ccc(C)cc2)C(C)=O)cc1
CI
0
CCOc1ccc(NC(=O)C(=Cc2ccccc2)C(C)=O)cc1
CI
0
COc1ccc(NC(=O)C(=Cc2ccccc2)C(C)=O)cc1
CI
0
Cc1ccc(NC(=O)C(C#N)=Cc2ccccc2)c(C)c1
CI
0
CC(=O)C(=Cc1ccccc1)C(=O)Nc1ccccc1
CI
0
COc1ccc(C=C(C(C)=O)C(=O)Nc2ccccc2)cc1
CI
0
COc1ccccc1NC(=O)C(=Cc1ccccc1)C(C)=O
CI
0
CC(=O)C(=Cc1ccccc1O)C(=O)Nc1ccccc1C
CI
0
CC(=O)C(=Cc1cccc([N+](=O)[O-])c1)C(=O)Nc1ccccc1C
CI
0
Cc1cc(N(CCC#N)CCC#N)ccc1C=CC(=O)Nc1ccccc1
CI
0
Cc1cccc(NC(=O)C=Cc2ccc(N(CCC#N)CCC#N)cc2C)c1
CI
0
Cc1cc(N(CCC#N)CCC#N)ccc1C=CC(=O)Nc1ccccc1Cl
CI
0
Cc1cc(N(CCC#N)CCC#N)ccc1C=CC(=O)Nc1cccc(Cl)c1
CI
0
NNC(=O)CC(=O)N(C(=O)C=Cc1ccccc1)c1ccc(Cl)cc1
CI
0
COc1ccc(NC(=O)C(C#N)=Cc2ccc(O)c(O)c2)cc1O
CI
0
N#CC(=Cc1ccc(O)c(O)c1)C(=O)Nc1ccc(C(=O)O)cc1
CI
0
O=C(C=Cc1ccccc1)Nc1ccccc1SCCCCl
CI
0
Cc1c(C)[n+]([O-])c2cc(C=[N+]([O-])CCO)ccc2[n+]1[O-]
CI
0
Cc1c(CO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
[O-][n+]1c(O)c(S)[n+]([O-])c2ccccc21
CI
0
Cc1c(C(=O)NCCO)[n+]([O-])c2cc(Cl)ccc2[n+]1[O-]
CI
0
COc1ccc2c(c1)[n+]([O-])c(C(C)=NNC(N)=S)c(C)[n+]2[O-]
CI
0
COc1ccc2c(c1)[n+]([O-])c(C(C)=O)c(C)[n+]2[O-]
CI
0
Cc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
O=C(NCCO)c1c(CO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
COCc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
CCOCc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
CC(C)(C)NCc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
CCN(CC)Cc1c(C(=O)NCCO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
O=C(NCCO)c1c(CN(CCO)CCO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
Cc1c(C(=O)N(CCO)CCO)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
COc1ccc2c(c1)[n+]([O-])c(C(C)=NNC(=O)CC#N)c[n+]2[O-]
CI
0
Cc1c(C(=O)CC(=NNC(=O)CC#N)C(N)=O)[n+]([O-])c2ccccc2[n+]1[O-]
CI
0
CN(C)CCCNc1c(C#N)[n+]([O-])c2cc(Cl)ccc2[n+]1[O-]
CI
0
O=C1NC(O)c2ccccc2O1
CI
0
O=C1NC(O)c2cc(CO)ccc2O1
CI
0
CC(=O)OCc1ccc2c(c1)C(O)NC(=O)O2
CI
0
O=C1NC(O)c2cc(Cl)ccc2O1
CI
0
O=C1NC(O)c2cc(Cl)cc(Cl)c2O1
CI
0
O=C1NC(O)c2cc(O)ccc2O1
CI
0
COc1ccc2c(c1)C(O)NC(=O)O2
CI
0
O=Cc1ccc2c(c1)C(O)NC(=O)O2
CI
0
CC(C)OC1NC(=O)Oc2ccccc21
CI
0
O=C1NC(O)c2cccc(Cl)c2O1
CI
0
COc1cccc2c1OC(=O)NC2O
CI
0
COCc1ccc2c(c1)C(O)NC(=O)O2
CI
0
O=C1NC(O)c2cccc([N+](=O)[O-])c2O1
CI
0
CCOC1NC(=O)Oc2ccccc21
CI
0
COC1NC(=O)Oc2c(F)cccc21
CI
0
COC(=O)c1ccc2c(c1)C(O)NC(=O)O2
CI
0
O=C1NC(O)c2c(F)cccc2O1
CI
0
Clc1ccc(CN2COc3c(ccc4cccnc34)C2)cc1Cl
CI
0
Cc1cc2c(c3ncccc13)OCN(Cc1ccc(Cl)cc1)C2
CI
0
Cc1cc2c(c3ncccc13)OCN(Cc1ccc(Cl)c(Cl)c1)C2
CI
0
COc1ccc(CN2COc3c(cc(C)c4cccnc34)C2)cc1
CI
0
Clc1ccccc1CN1COc2c(cc(Cl)c3cccnc23)C1
CI
0
Clc1ccc(CN2COc3c(ccc4cccnc34)C2)cc1
CI
0
COc1ccc(CN2COc3c(ccc4cccnc34)C2)cc1
CI
0
Clc1ccc(CN2COc3c(ccc4cccnc34)C2)c(Cl)c1
CI
0
Fc1ccc(CN2COc3c(ccc4cccnc34)C2)cc1
CI
0
Clc1ccc(CN2COc3c(cc(Cl)c4cccnc34)C2)cc1Cl
CI
0
Clc1ccc(CN2COc3c(cc(Cl)c4cccnc34)C2)cc1
CI
0
Clc1ccccc1CN1COc2c(ccc3cccnc23)C1
CI
0
Clc1cc2c(c3ncccc13)OCN(Cc1ccccc1)C2
CI
0
COc1ccc(CN2COc3c(cc(Cl)c4cccnc34)C2)cc1
CI
0
Fc1ccc(CN2COc3c(cc(Cl)c4cccnc34)C2)cc1
CI
0
Fc1ccccc1CN1COc2c(cc(Cl)c3cccnc23)C1
CI
0
Clc1ccc(CN2COc3c(cc(Cl)c4cccnc34)C2)c(Cl)c1
CI
0
CC1(Cl)C2c3ccccc3C(c3ccccc32)C1(C)Cl
CI
0
CC1(Br)C2c3ccccc3C(c3ccccc32)C1(C)C(Cl)(Cl)Cl
CI
0
CC(=O)OC1(C)C2c3ccccc3C(c3ccccc32)C1(C)C
CI
0
NNC(=O)C1CC2c3ccccc3C1c1ccccc12
CI
0
NNC(=O)C1C2c3ccccc3C(c3ccccc32)C1C(=O)O
CI
0
COC(=O)C1CC2c3ccccc3C1c1ccccc12
CI
0
NNC(=O)C1C2c3ccccc3C(c3ccccc32)C1C(=O)NN
CI
0
CCOC(=O)C1C2c3ccccc3C(c3ccccc32)C1C(=O)OCC
CI
0
c1ccc2c(c1)C1CCC2c2ccccc21
CI
0
NC12CCC(N)(c3ccccc31)c1ccccc12
CI
0
CC12CCC(C)(c3cc(O)c(O)cc31)c1cc(O)c(O)cc12
CI
0
CC(=O)Oc1cc2c(cc1OC(C)=O)C1(C)CCC2(C)c2cc(OC(C)=O)c(OC(C)=O)cc21
CI
0
O=C(O)C1C2c3ccccc3C(c3ccccc32)C1C(=O)O
CI
0
CCCCCCCCCCCCCCCCCCSCC12c3ccccc3C(c3ccccc31)C(COS(=O)(=O)O)C2COS(=O)(=O)O.[NaH]
CI
0
CCCCCCCCCCCCSCC12c3ccccc3C(c3ccccc31)C(C(=O)O)C2C(=O)O
CI
0
CSC(=S)CC(O)C1CC2c3ccccc3C1c1ccccc12
CI
0
CS(=O)(=O)NC12CCC(c3ccccc31)c1ccccc12
CI
0
CC1(c2cccc3ccccc23)OC(=O)c2ccccc21
CI
0
O=C1OC(c2cccc3ccccc23)c2ccccc21
CM
1
O=C1OC(c2cccc3c(F)cccc23)c2ccccc21
CI
0
COc1ccc(C2OC(=O)c3ccccc32)c2ccccc12
CI
0
COc1ccc(C2(C)OC(=O)c3ccccc32)c2ccccc12
CI
0
Cc1cccc2c1C(=O)OC2(C)c1cccc2ccccc12
CI
0