smiles
stringlengths
4
580
activity
stringclasses
3 values
HIV_active
int64
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1
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CI
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COC(=N)C(C#N)=NC1OCC(O)C(O)C1O
CI
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COC1CC(N)C(O)C(CN=[N+]=[N-])O1
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CC[As](CC)SCC1OC(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
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CC(OC1C(N)C(O)OC(CO)C1O)C(=O)O
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CC(=O)OCC1OC(OC(C)=O)C(NC(=O)CI)C(OC(C)=O)C1OC(C)=O
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COP(=O)(CC(=O)CCCCCOC1CCCCO1)OC
CI
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CC=C(CCCCOC1CCCCO1)[Si](C)(C)C
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ClCCCCOC1CCCCO1
CI
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CCCCCCCCCCCCCCCCCC(=O)OCC(COC1OC(CS(=O)(=O)O)C(O)C(O)C1O)OC(=O)CCCCCCCCCCCCCCCCC.[NaH]
CI
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COC1CCC(O)C(CO)O1
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COC1CCC(OS(C)(=O)=O)C(CO)O1
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COC1CC(OC)C(O)C(CO)O1
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CCOC(=O)CC(C)OC1CCCCO1
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CCCCCCCCCCCCCCCCCC(=O)OCC(COC1OC(COS(=O)(=O)O)C(O)C(O)C1O)OC(=O)CCCCCCCCCCCCCCCCC.[NaH]
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CCCOC1OC(CS(=O)(=O)O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O.[NaH]
CI
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C=CCOC1OC(CS(=O)(=O)O)C(O)C(O)C1O.[NaH]
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CC(=O)OC1C(CCl)OC(N=[N+]=[N-])C(OC(C)=O)C1OC(C)=O
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CCOC(=O)C#CCCC=C(C)COC1CCCCO1
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CCCCCCCCSC1OC(CO)C(O)C(O)C1O
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CCOC(=O)C#CCCOC1CCCCO1
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CCC=CCC=CCC=CCC=CCCC(=O)OC(COC(=O)CCCCCCCC=CCC=CCC=CCC)COC1OC(CO)C(O)C(O)C1O
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CCCCCCCCCCCCCCCC(=O)OCC1OC(OC)C(NC(=O)N(CCCl)N=O)C(O)C1O
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CCCCCCCCCCCCCCCCOC1OC(CBr)C(O)C(O)C1O
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CCCCCCCCCCCCCCCCOC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1O
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CCCCCCCCCCCCCCCCOCC(COC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O)OCCCCCCCCCCCCCCCC
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CCCCCCCCCCCCCCCCOC1OC(CO)C(O)C(O)C1O
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CCCCCCCCCCCCCCCCOCC(COC1OC(CO)C(O)C(O)C1O)OCCCCCCCCCCCCCCCC
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CCCCCCCCCCCCCCCCOC1OC(CS(=O)(=O)O)C(O)C(O)C1O.[NaH]
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CCCCCCCCCCCCCCCCOCC(COC1OC(CS(=O)(=O)O)C(O)C(O)C1O)OCCCCCCCCCCCCCCCC.[NaH]
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CCCCCCCCCCCCCCCCOCC(COC1OC(CO)C(O)C(O)C1O)OCCCCCCCCCCCCCCCC.ClC(Cl)Cl
CI
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CCCCCC.CCCCCCCCCCCCOC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
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CCCCCCCCOC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
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CCCCCCCCCCCCCCCCCCCCOC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
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CCCCCCCCCCCCCCCCCCCCOC1OC(CO)C(O)C(O)C1O.ClC(Cl)Cl
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CCCCCCCCCCCCOC1OC(CO)C(O)C(O)C1O
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CCC=CCC=CCC=CCCCCCCCC(=O)OCC(COC1OC(CS(=O)(=O)O)C(O)C(O)C1O)OC(=O)CCCCCCCCCCCCCCC.[NaH]
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COC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1NC(=O)N(CCCl)N=O
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COC1OC(CO)C(O)C(OC(C)=O)C1NC(=O)N(CCCl)N=O
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CCCCCCCCCCCC(=O)OCC1OC(OC)C(NC(=O)N(CCCl)N=O)C(O)C1O
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CCCCCCCCCCCCCC(=O)OCC1OC(OC)C(NC(=O)N(CCCl)N=O)C(O)C1O
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CCCCCCCCCCCCCC(=O)OC1C(O)C(CO)OC(OC)C1NC(=O)N(CCCl)N=O
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CCCCCCCCCCCCCCCCCC(=O)OCC1OC(OC)C(NC(=O)N(CCCl)N=O)C(O)C1O
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CCCCCCCCCCCCCCCC(=O)OC1C(O)C(CO)OC(OC)C1NC(=O)N(CCCl)N=O
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CCCCCCCC(=O)OCC1OC(OC)C(NC(=O)N(CCCl)N=O)C(O)C1O
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CC(O)C(C(=O)O)N(CC1(O)OCC(O)C(O)C1O)N=O
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CC(C)C(C(=O)O)N(CC1(O)OCC(O)C(O)C1O)N=O
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CSCCC(C(=O)O)N(CC1(O)OCC(O)C(O)C1O)N=O
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CC(=O)NC1C(O)OC(CO)C(O)C1OC(C)C(=O)NC(CC(N)=O)C(=O)NC(CCC(=O)O)C(N)=O
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CC=CC#CC#CC(O)C(C=CCCCO)OC1OC(CO)C(O)C(O)C1O
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CCCCCC=CCC=CCCCCCCCC(=O)OCC(COC1OC(CS(=O)(=O)O)C(O)C(O)C1O)OC(=O)CCCCCCCC=CCC=CCCCCC.[NaH]
CI
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CC(=O)OCC1OC(OC(C)=O)C(NC#N)C(OC(C)=O)C1OC(C)=O
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CC(C)(C)C(=O)OCC1OC(N=[N+]=[N-])C(OC(=O)C(C)(C)C)C(OC(=O)C(C)(C)C)C1OC(=O)C(C)(C)C
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COC1CCC(OS(C)(=O)=O)CO1
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C=C(C)COC1CCCCO1
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COC1(C)CCC(OS(C)(=O)=O)CO1
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COC1CCC(OS(C)(=O)=O)C(C)O1
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CCOC1OC(C)(C=C(C#N)C#N)CCC1C
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OCC1OC(NC(=S)NCSCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(O)C(O)C1O
CI
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OCC1OC(NC(=S)NCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(O)C(O)C1O
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O=C(NCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NC1OC(CO)C(O)C(O)C1O
CI
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COC1OC(COC(=O)NCCCCC(=O)C(F)(F)F)C(O)C(O)C1O
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COC1OC(COC(=O)NCCCCC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(O)C(O)C1O
CI
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CC(CCC#CC(=O)O)OC1CCCCO1
CI
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COC1CC(C)(N)C(O)C(C)O1
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CCCC1(N)CC(OC)OC(C)C1O
CI
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COC1CC(C)([N+](=O)[O-])C(O)C(C)O1
CI
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CCCCCC(C)SC1(C(=O)OC)CC(OC(C)=O)C(NC(C)=O)C(C(OC(C)=O)C(COC(C)=O)OC(C)=O)O1
CI
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[N-]=[N+]=CC(=O)OC1CCOCC1
CI
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CC(CC(=O)O)OC1OC(COC(=O)C(C)(C)C)C(OC(=O)C(C)(C)C)C(OC(=O)C(C)(C)C)C1OC(=O)C(C)(C)C
CI
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CC(CCO)OC1OC(COC(=O)C(C)(C)C)C(OC(=O)C(C)(C)C)C(OC(=O)C(C)(C)C)C1OC(=O)C(C)(C)C
CI
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CC1(C(=O)O)CCC(C(=O)O)C(C)(C)O1
CI
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COC(=O)C=C(C)C=CCOC1CCCCO1
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CCCCC(C=CCOC1CCCCO1)=CC(=O)OCC
CI
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CCOC(=O)C(C(=O)OCC)C(=S)NC1OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
CI
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CC(=O)OCC1OC(OCCCCCCO)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O
CI
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COC1OC(OCCC#N)C(OCCC#N)C(OCCC#N)C1OCCC#N
CI
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C=C(C(=O)O)C1CCC(CCC=C(C)CCC=C(C)CCC=C(C)C)CO1
CI
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CC(=CC(=O)OCCCCCCCC(N)=O)C(O)C1OCC(CC=CC(C)C(C)O)C(O)C1O
CI
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NNC(=O)CCc1c[nH]c2ccccc12
CI
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CCOC(=O)C(Cc1c[nH]c2ccc(N)cc12)(NC(C)=O)C(=O)OCC
CI
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CC(=O)O.CCC(N)Cc1c[nH]c2ccccc12
CI
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CCOC(=O)Cc1c[nH]c2ccc(N(CCO)CCO)cc12
CI
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COc1ccc2[nH]cc(CCNC(C)=O)c2c1
CI
0
Cc1[nH]c2cc([N+](=O)[O-])ccc2c1[N+](=O)[O-]
CI
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O=[N+]([O-])C=Cc1cc2ccccc2[nH]1
CI
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Cn1c(CC(O)(C(F)(F)F)C(F)(F)F)c(C(O)(C(F)(F)F)C(F)(F)F)c2ccccc21
CI
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CCOP(=O)(CC(=O)c1cc2ccccc2[nH]1)OCC
CI
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COc1ccc2[nH]c(C)cc2c1CN
CI
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COC(=O)C(=Cc1c[nH]c2ccccc12)NC=O
CI
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CCOC(=O)C(=CNC(Cc1c[nH]c2ccccc12)C(=O)OC)C(=O)OCC
CI
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CSc1c(S(C)=O)[nH]c2cc(Br)cc(Br)c12
CI
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C=CCCCn1ccc2ccccc21
CI
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Cc1[nH]c2c(C)c([N+](=O)[O-])c(C)c([N+](=O)[O-])c2c1[N+](=O)[O-]
CI
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Cn1cc(C(=O)C(Cl)=C(Cl)C(=O)O)c2ccccc21
CI
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COc1ccc2c(CCNC(C)=O)c(C(C)=O)[nH]c2c1
CI
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CCOC(=O)C(=CC=CNCCc1c[nH]c2ccccc12)C(=O)OCC
CI
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CCOC(=O)C(=CC=CNC(Cc1c[nH]c2ccccc12)C(N)=O)C(=O)OCC
CI
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CC(C)=CCCC(C)=CCCC(C)=CCc1c[nH]c2ccccc12
CI
0