Files changed (1) hide show
  1. README.md +24 -24
README.md CHANGED
@@ -21,7 +21,7 @@ task_categories:
21
  task_ids:
22
  - instance-segmentation
23
  size_categories:
24
- - around_10k
25
  dataset_info:
26
  features:
27
  - name: id
@@ -45,17 +45,16 @@ configs:
45
 
46
  # SynthMT: A Synthetic Benchmark for Automated Microtubule Segmentation
47
 
48
- **Authors:** Mario Koddenbrock*, Justus Westerhoff*, Dominik Fachet, Simone Reber, Felix Gers, Erik Rodner
49
- **Affiliations:** HTW Berlin, BHT Berlin, MPI for Infection Biology
 
50
 
51
- **Project Page:** https://datexis.github.io/SynthMT-project-page/
52
- **Code & Pipeline:** https://github.com/ml-lab-htw/SynthMT
53
- **Paper:** *Synthetic Data Enables Human-Grade Microtubule Analysis with Foundation Models for Segmentation*
54
- **Dataset:** https://huggingface.co/datasets/HTW-KI-Werkstatt/SynthMT
55
 
56
- _`*Equal contribution`_
57
 
58
- # 🧬 Overview
59
 
60
  **SynthMT** is a synthetic, expert-validated dataset designed to benchmark segmentation models on *in vitro* microtubule (MT) images visualized in interference reflection microscopy (IRM)–like conditions.
61
  It provides:
@@ -70,7 +69,7 @@ A core result of the associated paper:
70
 
71
  ---
72
 
73
- # 🖼 Example from the Dataset
74
 
75
  <div align="center">
76
 
@@ -85,25 +84,25 @@ A core result of the associated paper:
85
  </tr>
86
  </table>
87
 
88
- ** Overview of SynthMT and example predictions.**
89
 
90
  </div>
91
 
92
  ---
93
 
94
- # 📦 Dataset Structure
95
 
96
  Each sample in SynthMT contains:
97
 
98
  | Field | Type | Description |
99
  |---|---|---|
100
  | `id` | `string` | Unique image identifier |
101
- | `image` | `Image` | Synthetic IRM-like image, decoded from PNG. Can be converted to a numpy array `(H, W, 3)` for in-memory processing. |
102
  | `mask` | `Array3D` | **Stack of instance masks** with shape `(C, 512, 512)` and `uint16` dtype, where `C` = number of instances in the image. Background pixels = 0. Stored in the dataset as a `Sequence(Image())` but can be stacked in memory for in-memory pipelines. |
103
 
104
  ---
105
 
106
- # 🧫 Biological Motivation
107
 
108
  Microtubules (MTs) are cytoskeletal filaments essential for intracellular transport, cell motility, and mitotic spindle formation. Measuring MT **count**, **length**, and **curvature** is critical for *in vitro* reconstitution experiments, drug discovery, and mechanistic cell biology.
109
 
@@ -117,7 +116,7 @@ However:
117
 
118
  ---
119
 
120
- # 📥 Installation & Loading
121
 
122
  Install the Hugging Face `datasets` library:
123
 
@@ -135,7 +134,7 @@ ds = load_dataset("HTW-KI-Werkstatt/SynthMT", split="train")
135
 
136
  sample = ds[0]
137
 
138
- # Image as numpy array (H, W, 3)
139
  img_array = np.array(sample["image"].convert("RGB"))
140
 
141
  # Masks as stacked numpy array (C, H, W)
@@ -146,16 +145,19 @@ No disk I/O is required — everything can be used in-memory.
146
 
147
  ---
148
 
149
- # 🔗 Links
150
 
151
  * **Project Page:** [https://datexis.github.io/SynthMT-project-page/](https://datexis.github.io/SynthMT-project-page/)
152
- * **Dataset:** [https://huggingface.co/datasets/HTW-KI-Werkstatt/SynthMT](https://huggingface.co/datasets/HTW-KI-Werkstatt/SynthMT)
 
153
  * **Code & Generation Pipeline:** [https://github.com/ml-lab-htw/SynthMT](https://github.com/ml-lab-htw/SynthMT)
154
  * **Paper:** [https://www.biorxiv.org/content/10.64898/2026.01.09.698597v2](https://www.biorxiv.org/content/10.64898/2026.01.09.698597v2)
155
 
156
  ---
157
 
158
- # 📄 Citation
 
 
159
 
160
  ```bibtex
161
  @article{koddenbrock2026synthetic,
@@ -173,19 +175,17 @@ No disk I/O is required — everything can be used in-memory.
173
 
174
  ---
175
 
176
- # 🏷 License
177
 
178
  **CC-BY-4.0** - See [LICENSE](LICENSE) for details.
179
 
180
  ---
181
 
182
- # 🙏 Acknowledgements
183
 
184
  Our work is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) Project-ID 528483508 - FIP 12.
185
  We would like to thank Dominik Fachet and Gil Henkin from the Reber lab for providing data,
186
  and also thank the further study participants Moritz Becker, Nathaniel Boateng, and Miguel Aguilar.
187
  The Reber lab thanks staff at the Advanced Medical Bioimaging Core Facility (Charité, Berlin) for imaging support
188
  and the Max Planck Society for funding. Furthermore, we thank Kristian Hildebrand and Chaitanya A. Athale (IISER Pune, India)
189
- and his lab for helpful discussions
190
-
191
-
 
21
  task_ids:
22
  - instance-segmentation
23
  size_categories:
24
+ - 1K<n<10K
25
  dataset_info:
26
  features:
27
  - name: id
 
45
 
46
  # SynthMT: A Synthetic Benchmark for Automated Microtubule Segmentation
47
 
48
+ - **Authors:** Mario Koddenbrock*, Justus Westerhoff*, Dominik Fachet, Simone Reber, Felix Gers, Erik Rodner
49
+ - *Equal contribution
50
+ - **Affiliations:** HTW Berlin, BHT Berlin, MPI for Infection Biology
51
 
52
+ - **Project Page:** https://datexis.github.io/SynthMT-project-page/
53
+ - **Code & Pipeline:** https://github.com/ml-lab-htw/SynthMT
54
+ - **Paper:** [*Synthetic Data Enables Human-Grade Microtubule Analysis with Foundation Models for Segmentation*](https://www.biorxiv.org/content/10.64898/2026.01.09.698597v2)
 
55
 
 
56
 
57
+ ## 🧬 Overview
58
 
59
  **SynthMT** is a synthetic, expert-validated dataset designed to benchmark segmentation models on *in vitro* microtubule (MT) images visualized in interference reflection microscopy (IRM)–like conditions.
60
  It provides:
 
69
 
70
  ---
71
 
72
+ ## 🖼 Example from the Dataset
73
 
74
  <div align="center">
75
 
 
84
  </tr>
85
  </table>
86
 
87
+ **Overview of SynthMT and example predictions.**
88
 
89
  </div>
90
 
91
  ---
92
 
93
+ ## 📦 Dataset Structure
94
 
95
  Each sample in SynthMT contains:
96
 
97
  | Field | Type | Description |
98
  |---|---|---|
99
  | `id` | `string` | Unique image identifier |
100
+ | `image` | `Image` | Synthetic IRM-like image, decoded from PNG. Can be converted to a numpy array `(512, 512, 3)` for in-memory processing. |
101
  | `mask` | `Array3D` | **Stack of instance masks** with shape `(C, 512, 512)` and `uint16` dtype, where `C` = number of instances in the image. Background pixels = 0. Stored in the dataset as a `Sequence(Image())` but can be stacked in memory for in-memory pipelines. |
102
 
103
  ---
104
 
105
+ ## 🧫 Biological Motivation
106
 
107
  Microtubules (MTs) are cytoskeletal filaments essential for intracellular transport, cell motility, and mitotic spindle formation. Measuring MT **count**, **length**, and **curvature** is critical for *in vitro* reconstitution experiments, drug discovery, and mechanistic cell biology.
108
 
 
116
 
117
  ---
118
 
119
+ ## 📥 Installation & Loading
120
 
121
  Install the Hugging Face `datasets` library:
122
 
 
134
 
135
  sample = ds[0]
136
 
137
+ # Image as numpy array (H, W, 3) = (512, 512, 3)
138
  img_array = np.array(sample["image"].convert("RGB"))
139
 
140
  # Masks as stacked numpy array (C, H, W)
 
145
 
146
  ---
147
 
148
+ ## 🔗 Links
149
 
150
  * **Project Page:** [https://datexis.github.io/SynthMT-project-page/](https://datexis.github.io/SynthMT-project-page/)
151
+ * **This Dataset:** [https://huggingface.co/datasets/HTW-KI-Werkstatt/SynthMT](https://huggingface.co/datasets/HTW-KI-Werkstatt/SynthMT)
152
+ * **Real IRM in-vitro MT dataset (also used in our paper):** [https://huggingface.co/datasets/HTW-KI-Werkstatt/IRM-in-vitro-microtubules](https://huggingface.co/datasets/HTW-KI-Werkstatt/IRM-in-vitro-microtubules)
153
  * **Code & Generation Pipeline:** [https://github.com/ml-lab-htw/SynthMT](https://github.com/ml-lab-htw/SynthMT)
154
  * **Paper:** [https://www.biorxiv.org/content/10.64898/2026.01.09.698597v2](https://www.biorxiv.org/content/10.64898/2026.01.09.698597v2)
155
 
156
  ---
157
 
158
+ ## 📄 Citation
159
+
160
+ If you use this dataset, please cite:
161
 
162
  ```bibtex
163
  @article{koddenbrock2026synthetic,
 
175
 
176
  ---
177
 
178
+ ## 🏷 License
179
 
180
  **CC-BY-4.0** - See [LICENSE](LICENSE) for details.
181
 
182
  ---
183
 
184
+ ## 🙏 Acknowledgements
185
 
186
  Our work is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) Project-ID 528483508 - FIP 12.
187
  We would like to thank Dominik Fachet and Gil Henkin from the Reber lab for providing data,
188
  and also thank the further study participants Moritz Becker, Nathaniel Boateng, and Miguel Aguilar.
189
  The Reber lab thanks staff at the Advanced Medical Bioimaging Core Facility (Charité, Berlin) for imaging support
190
  and the Max Planck Society for funding. Furthermore, we thank Kristian Hildebrand and Chaitanya A. Athale (IISER Pune, India)
191
+ and his lab for helpful discussions