chembl_id
stringlengths
7
13
canonical_smiles
stringlengths
1
2.03k
CHEMBL7721
O=C(/C=C/c1ccc(Cl)c(Cl)c1)c1ccc(O)cc1
CHEMBL7722
Cc1cc(-c2c(F)cc3c(=O)c(CC4CCCCC4)cn(C4CC4)c3c2F)cc(C)n1
CHEMBL8004
CCCC(=O)Nc1ccc(Nc2cccc3c2CCO3)cc1
CHEMBL8005
C=C1CC(C)(c2ccccc2)OC1=O
CHEMBL8006
C=C1CC(C)(CC(C)(C)C)OC1=O
CHEMBL8007
C=CCC1Oc2cccc(Cl)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3
CHEMBL8008
COC(=O)C(C)(C)CCCOc1cccc(OCCCC(C)(C)C(=O)OC)c1N
CHEMBL3311138
CC(C)C[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
CHEMBL8305
CC(C)c1ccc(C(c2ccccc2)c2ccc(C(C)C)cc(=O)c2O)c(O)c(=O)c1
CHEMBL1163215
C(=C/c1ccc(-c2cccs2)s1)\c1ccccn1.I
CHEMBL8032
CCCC(=O)Nc1ccc(Oc2cccc3c2OCCO3)cc1
CHEMBL8033
Oc1cccc([C@@H]2CCCNC2)c1
CHEMBL3311276
Cc1c(-c2ccc(-c3cc4ccc(C5=NCCCN5)cc4o3)cc2)[nH]c2cccc(C#N)c12
CHEMBL7703
COc1cccc(Oc2ccc(NC(=O)C(C)C)cc2)c1
CHEMBL7790
Oc1ccc2c(cc3ccc4cccc5ccc2c3c45)c1O
CHEMBL7791
O=C1c2ccc(OCc3ccccc3)cc2CCC1CC(=O)N1CCC(c2ccccc2)CC1
CHEMBL7793
CN(C)c1ncnc2c1ncn2C1Cc2ccccc2C1
CHEMBL3311402
C=C1C(=O)O[C@H]2/C=C(C)\C=C/[C@H]3O[C@]3(C)C[C@@H](OC(=O)CCC)[C@@H]12
CHEMBL4553564
CCNC1CCOC(C)(C)C1
CHEMBL7723
CSc1ncnc2c1ncn2Cc1ccccc1
CHEMBL7724
Cc1cc2ncc(-c3ccccc3)nc2cc1C
CHEMBL7725
Cc1cc(N)ccc1C(=O)OCC(O)CNC(C)(C)C
CHEMBL7813
CCN(CC)CCNCCNc1ccc2ncn3c4ccccc4c(=O)c1c23
CHEMBL7814
O=C(c1ccccc1)C(c1ccccc1)C1OCCc2ccccc21
CHEMBL7815
C#C[C@]1(O)CCC2C3C(CC[C@@]21C)C1CCC(=O)C=C1C[C@H]3C
CHEMBL3311465
O=C(CCCCCCC(=O)Nc1ccc2c(c1)CCC(=O)N2)NO
CHEMBL7746
COC(=O)C(C)(C)CCCOc1ccc(OCCCC(C)(C)C(=O)OC)c(/C=N/NC(N)=O)c1
CHEMBL7747
O=C(/C=C/c1ccc(O)cc1)c1ccccc1
CHEMBL31
COc1c(N2CCNC(C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12
CHEMBL7748
Nc1nc2ccc(OCc3ccccc3)cc2c2nc(-c3ccco3)nn12
CHEMBL7749
CCCOC(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1
CHEMBL3311145
C=CCOc1ccc2c(=O)c(-c3cc(OC)c(OC)cc3OC)coc2c1
CHEMBL4553588
NC(=O)CSc1nnc2c(=O)n(-c3ccc(F)cc3)ccn12
CHEMBL4553589
Cc1cc(-c2csc(Cc3ccccc3)n2)c(C)n1NC(=O)c1nn(C)c(=O)c2ccccc12
CHEMBL4553590
Cc1ccc2c(N)c(C(=O)NCCc3ccc(N4CCNCC4)c(-c4ccccn4)c3)sc2n1
CHEMBL4553591
O=C(N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc(-c3ccc(-c4cnc([C@@H]5CCCN5C(=O)[C@H](NC(=O)N5CCCCC5)c5ccccc5)s4)cc3)cc2)s1)c1ccccc1)N1CCCCC1
CHEMBL4553592
CC(C)=CCN1C[C@@H]2CC[C@H]1CN(S(=O)(=O)c1cccnc1)C2
CHEMBL3311150
COc1cc(OC)c(-c2coc3cc(OCc4ccccc4F)ccc3c2=O)cc1OC
CHEMBL8035
Cn1c(C(F)(F)F)nc(-c2cc(Cl)cc(Cl)c2)c1-c1cc(Cl)cc(Cl)c1
CHEMBL8036
CN1C(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc2C1=O
CHEMBL8037
CCc1cccc(Oc2cnc(O)nc2)c1
CHEMBL8122
CN(C(=O)[C@H](CC#Cc1ccc(N)cc1)NS(=O)(=O)c1ccc2ccccc2c1)C1CCCC1
CHEMBL8123
N#CN1CCC1
CHEMBL3311289
CC(C)C[C@@H](NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
CHEMBL4553609
Cc1cc(C2CCCN2C(=O)[C@@H]2CCCN2)on1
CHEMBL4553610
CC1(C)C(=O)N(c2ccc(S(F)(F)(F)(F)F)cc2)C(=S)N1c1ccc(C(F)(F)F)cc1
CHEMBL4553611
CCOC(=O)c1sc(N)c(C#N)c1COC(=O)C1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1
CHEMBL4553612
CCC[C@H]1CC[C@@H](n2c(=O)[nH]c3ccc(NC(C)=O)cc3c2=O)CC1
CHEMBL4553613
Cc1cc(CNS(=O)(=O)c2cc3cc(Cl)ccc3[nH]2)ccc1-c1ccc(F)cc1
CHEMBL4553614
Cc1c(C(=O)N2CCCC(c3n[nH]c(C4CC4)n3)C2)cnn1-c1nn2cccc2c(=O)[nH]1
CHEMBL4553615
NC1CCCN(c2ccccc2F)C1
CHEMBL4553616
Cc1cc(NC(=O)c2ccc(Cl)cc2)ccc1NS(=O)(=O)C(F)(F)F
CHEMBL1163189
CCCc1cc(OC)c(OCC(=O)OC)cc1O
CHEMBL7875
CCCC(=O)Nc1ccc(Cc2cccc3occc23)cc1
CHEMBL7876
CC(=O)N(C(=O)N=[S+]([O-])(c1ccc(C)cc1)N(C)C(C)=O)c1ccc(Cl)cc1
CHEMBL7877
Cc1cc(-c2c(F)cc3c(=O)c(Cc4ccc(O)cc4O)cn(C4CC4)c3c2F)cc(C)n1
CHEMBL7878
CC(C)(CCCOc1ccc([S+]([O-])CCCC(C)(C)C(=O)O)cc1)C(=O)O
CHEMBL1163196
CCCCc1cc(OC)c(OC)cc1OC
CHEMBL3311411
CCn1c(O)cc(C)cc1=O
CHEMBL4553639
O=C(NCc1ccc(F)cc1)c1cc(Cl)ccc1O
CHEMBL3311412
Nc1ccc2c(c1)N=C(O)CN2
CHEMBL3311419
Oc1csc2ccccc12
CHEMBL3311423
Cn1c(=O)c2nc(-c3cccc(O)c3O)nnc2n(C)c1=O
CHEMBL1163191
CC(C)=CCNc1ncnc2c1ncn2[C@H]1CC[C@@H](CO)O1
CHEMBL7816
CCCCCCCCC(=O)c1c(O)cc(CCCCCCCC)oc1=O
CHEMBL7896
CN(C)c1ncnc2c1ncn2Cc1cccc(Br)c1
CHEMBL7897
CS(=O)(=O)O.Cn1c(=N)n2nc(-c3ccco3)nc2c2ccccc21
CHEMBL7898
C#CCC(=O)Nc1ccc(Oc2cccc(OC)c2)cc1
CHEMBL7834
C=CC[C@]1(O)CCC2C3CCC4=CC(=O)CCC4C3CC[C@@]21C
CHEMBL7835
COc1ccc(-c2cc(OCCCC(C)(C)C(=O)O)ccc2OCCCC(C)(C)C(=O)O)cc1
CHEMBL7836
COC(=O)C(C)(C)CCCOc1ccc(C(=O)c2ccc(OCCCC(C)(C)C(=O)OC)cc2)cc1
CHEMBL3311159
COc1cc(OC)c(-c2coc3cc(OCc4cccc(F)c4)ccc3c2=O)cc1OC
CHEMBL8124
N#CN/C(=N\C(Cn1ccnc1)c1ccc(Cl)cc1Cl)Nc1ccc(Cl)cc1
CHEMBL8125
CC(C)(C)NCC(O)COc1ccc(NC(=O)c2cccs2)cc1C(=O)O
CHEMBL8126
CCCCOC(=O)c1cc(OC)c(CC(C)N)cc1OC
CHEMBL8127
CC(C)(CCOc1ccc(OCCC(C)(C)C(=O)O)cc1)C(=O)O
CHEMBL3311304
COc1ccc(S(=O)(=O)Nc2cccc(C)c2)cc1
CHEMBL3311306
COc1ccc(S(=O)(=O)Nc2c(C)cccc2C)cc1
CHEMBL3311311
COc1ccccc1S(=O)(=O)Nc1c(C)cc(C)cc1C
CHEMBL3311314
Cc1ccc(S(=O)(=O)Nc2c(C)cc(C)cc2C)cc1
CHEMBL38030
CC(C)Oc1cccc(CC(=O)N2CCCC(CC[N+]3(C)CCC4(CC3)c3ccccc3C[S+]4[O-])(c3ccc(Cl)c(Cl)c3)C2)c1.[I-]
CHEMBL7967
CC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1
CHEMBL7969
NC1=NC(c2ccc(F)cc2)Cc2c(F)cccc21
CHEMBL7970
Oc1ccc2ccc3c4ccccc4ccc3c2c1
CHEMBL3311428
Cn1cc(OCc2ccccc2)c(=O)cc1CNCCCCCCNc1ccnc2cc(Cl)ccc12
CHEMBL7900
CCCCCCCCOC(=O)[C@]12CCC(C)(C)CC1C1C(=O)C=C3[C@@](C)(CC[C@H]4C(C)(C)C(=O)C(C#N)=C[C@]34C)[C@]1(C)CC2
CHEMBL7901
CCCCCCCCCCCCCCCCCC(=O)OCC1OC(O)C(NC(C)=O)C(O[C@H](C)C(=O)N[C@@H](C)C(=O)NC(CCC(=O)O)C(N)=O)C1O
CHEMBL7988
C=CCC1Oc2ccc(F)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3
CHEMBL7990
COc1cccc(N(C)c2ccc(NC(=O)C(C)C)cc2)c1
CHEMBL3311038
COc1cc(OC)c(-c2coc3c4c(ccc3c2=O)OC(C)(C)C=C4)cc1OC
CHEMBL7920
CC(C)(Oc1cccc(OC(C)(C)C(=O)O)c1)C(=O)O
CHEMBL7922
COc1ccc(Oc2cnc(O)nc2)cc1
CHEMBL7924
CC1(C)CC[C@]2(C(=O)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)CC[C@]3(C)C(C(=O)C=C4[C@@]3(C)CC[C@H]3C(C)(C)C(=O)C(C#N)=C[C@]43C)C2C1
CHEMBL7925
Cn1c2ccccc2n2c(=O)c(-c3ccc(Cl)cc3)nnc12
CHEMBL7926
O=C(O)c1ccccc1OCCCOc1cc2c(cc1O)CCO2
CHEMBL8009
CC(C)NCC(O)COc1ccc(NC(=O)c2cccs2)cc1
CHEMBL8213
O=S(=O)(c1cccc2cccnc12)N1Cc2ccccc2N(Cc2c[nH]cn2)C(CCc2ccccc2)C1
CHEMBL8214
CCCCc1cc(OC)c(CC(C)N)cc1OC
CHEMBL8216
O=C1[C@@H](NS(=O)(=O)c2nc3cc(Cl)ccc3[nH]2)CCN1Cc1cc2c[nH]ccc-2n1
CHEMBL3311316
CC(=O)c1ccc(S(=O)(=O)Nc2c(C)cc(C)cc2C)cc1