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Bidirectional links between HIV and intimate partner violence in pregnancy: implications for prevention of mother-to-child transmission | <sec id="st1"><title>Introduction</title><p>Prevention of mother-to-child transmission (PMTCT) has the potential to eliminate new HIV infections among infants. Yet in many parts of sub-Saharan Africa, PMTCT coverage remains low, leading to unacceptably high rates of morbidity among mothers and new infections among infa... | <contrib contrib-type="author"><name><surname>Hatcher</surname><given-names>Abigail M</given-names></name><xref ref-type="corresp" rid="cor1">§</xref><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Woollett</surname><giv... | Journal of the International AIDS Society | <sec sec-type="intro" id="S0001"><title>Introduction</title><p>Prevention of mother-to-child transmission (PMTCT) has reduced new infant HIV infections from an estimated 32% in the absence of treatment [<xref rid="CIT0001" ref-type="bibr">1</xref>, <xref rid="CIT0002" ref-type="bibr">2</xref>], to as low as 1% [<xref r... |
Service, training, mentorship: first report of an innovative education-support program to revitalize primary care social service in Chiapas, Mexico | <sec id="st1"><title>Background</title><p>The Mexican mandatory year of social service following medical school, or pasantía, is designed to provide a safety net for the underserved. However, social service physicians (pasantes) are typically unpracticed, unsupervised, and unsupported. Significant demotivation,... | <contrib contrib-type="author"><name><surname>Van Wieren</surname><given-names>Andrew</given-names></name><xref ref-type="aff" rid="AF0001">1</xref></contrib><contrib contrib-type="author"><name><surname>Palazuelos</surname><given-names>Lindsay</given-names></name><xref ref-type="aff" rid="AF0002">2</xref></contrib><co... | Global Health Action | <p>Ever since the President of Mexico and the Dean of the Universidad Nacional Autónoma de México established an agreement in 1937, graduating Mexican medical students have been required to complete a year of primary care social service (called pasantía) before obtaining their full medical licen... |
The effect of immunonutrition (glutamine, alanine) on fracture healing | <sec id="st1"><title>Background</title><p>There have been various studies related to fracture healing. Glutamine is an amino acid with an important role in many cell and organ functions. This study aimed to make a clinical, radiological, and histopathological evaluation of the effects of glutamine on fracture healing.<... | <contrib contrib-type="author"><name><surname>Küçükalp</surname><given-names>Abdullah</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Durak</surname><given-names>Kemal</given-names><... | Food & Nutrition Research | <p>The classical definition of a fracture is the breaking of the entirety of a bone from internal or external forces. The bone is healed by reconstruction of osseous tissue without any scarring (<xref rid="CIT0001" ref-type="bibr">1</xref>). Fracture healing starts immediately after the injury and continues until the b... |
Foot-and-mouth disease virus leader proteinase: Structural insights into the mechanism of intermolecular cleavage | Could not extract abstract | <contrib contrib-type="author" id="au0005"><name><surname>Steinberger</surname><given-names>Jutta</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au0010"><name><surname>Grishkovskaya</surname><given-names>Irina</given-names></name><xref rid="aff0010" ref-type=... | Virology | <sec id="s0005"><title>Introduction</title><p id="p0030">Virally encoded proteinases play essential roles not only in the processing of the viral proteins but also in cleavage of host cell proteins in order to manipulate cellular processes to the advantage of the virus. One of the first such reactions to be documented ... |
Transmission of allergen-specific IgG and IgE from maternal blood into breast milk visualized with microarray technology | Could not extract abstract | <contrib contrib-type="author" id="au1"><name><surname>Hochwallner</surname><given-names>Heidrun</given-names></name><degrees>PhD</degrees><xref rid="aff1" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Alm</surname><given-names>Johan</given-names></name><degrees>MD, PhD</degree... | The Journal of Allergy and Clinical Immunology | <p content-type="salutation">To the Editor:</p><p id="p0010">Data from experimental animal models have previously shown that allergen-specific IgG antibodies are transmitted from the mother to the offspring via breast milk<xref rid="bib1" ref-type="bibr">1</xref>, <xref rid="bib2" ref-type="bibr">2</xref> and have prov... |
Gain-of-function mutations in signal transducer and activator of transcription 1 (<italic>STAT1</italic>): Chronic mucocutaneous candidiasis accompanied by enamel defects and delayed dental shedding | Could not extract abstract | <contrib contrib-type="author" id="au1"><name><surname>Frans</surname><given-names>Glynis</given-names></name><degrees>MPharm</degrees><xref rid="aff1" ref-type="aff">a</xref><xref rid="fn1" ref-type="fn">∗</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Moens</surname><given-names>Leen</... | The Journal of Allergy and Clinical Immunology | <p content-type="salutation">To the Editor:</p><p id="p0010">Heterozygous gain-of-function mutations in signal transducer and activator of transcription 1 <italic>(STAT1)</italic> have recently been identified as a cause of chronic mucocutaneous candidiasis (CMC). Uzel et al<xref rid="bib1" ref-type="bibr"><sup... |
Regulation of the calcium-sensing receptor expression by 1,25-dihydroxyvitamin D<sub>3</sub>, interleukin-6, and tumor necrosis factor alpha in colon cancer cells<sup><xref ref-type="fn" rid="d35e73">☆</xref></sup> | Could not extract abstract | <contrib contrib-type="author" id="aut0005"><name><surname>Fetahu</surname><given-names>Irfete S.</given-names></name><email>irfete.fetahu@meduniwien.ac.at</email><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Hummel</surname><given-names>Doris M.</given-... | The Journal of Steroid Biochemistry and Molecular Biology | <sec id="sec0005"><label>1</label><title>Introduction</title><p id="par0020">Epidemiological studies demonstrate an inverse correlation between calcium and vitamin D intake and risk of tumor development <xref rid="bib0005" ref-type="bibr">[1]</xref>, <xref rid="bib0010" ref-type="bibr">[2]</xref>. The calcium-sensing r... |
Estimating the burden of disease in chronic pain with and without neuropathic characteristics: Does the choice between the EQ-5D and SF-6D matter? | Could not extract abstract | <contrib contrib-type="author" id="au005"><name><surname>Torrance</surname><given-names>Nicola</given-names></name><email>n.torrance@dundee.ac.uk</email><xref rid="af005" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="author" id="au010"><name><surname>Lawson<... | Pain | <sec id="s0005"><label>1</label><title>Introduction</title><p id="p0005">Chronic pain is common, affecting up to half of the adult population <xref rid="b0085" ref-type="bibr">[17]</xref>, <xref rid="b0235" ref-type="bibr">[47]</xref>. Approximately 20% of the adult European population has significant chronic pain, and... |
Differential structural and resting state connectivity between insular subdivisions and other pain-related brain regions | Could not extract abstract | <contrib contrib-type="author" id="au005"><name><surname>Wiech</surname><given-names>K.</given-names></name><email>katja.wiech@ndcn.ox.ac.uk</email><xref rid="af005" ref-type="aff">a</xref><xref rid="af010" ref-type="aff">b</xref><xref rid="cor1" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="autho... | Pain | <sec id="s0005"><label>1</label><title>Introduction</title><p id="p0005">Of the various brain regions that have been implicated in the perception of pain, the insula has most consistently been reported across studies <xref rid="b0085" ref-type="bibr">[17]</xref>. Insular activation has been found during acute <xref rid... |
Multiple roles for Na<sub>V</sub>1.9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease–derived stimuli | Could not extract abstract | <contrib contrib-type="author" id="au005"><name><surname>Hockley</surname><given-names>James R.F.</given-names></name><xref rid="af005" ref-type="aff">a</xref><xref rid="af010" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au010"><name><surname>Boundouki</surname><given-names>George</given-names><... | Pain | <sec id="s0005"><label>1</label><title>Introduction</title><p id="p0005">Chronic dysregulation of visceral sensation can lead to abdominal pain, which is clinically challenging to treat. A hallmark of chronic visceral pain is heightened sensitivity to gut motility and distension of visceral organs, typically in respons... |
Anti-hyperalgesic effects of a novel TRPM8 agonist in neuropathic rats: A comparison with topical menthol | Could not extract abstract | <contrib contrib-type="author" id="au005"><name><surname>Patel</surname><given-names>Ryan</given-names></name><email>ryan.patel.10@ucl.ac.uk</email><xref rid="af005" ref-type="aff">a</xref><xref rid="cor1" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="author" id="au010"><name><surname>Gonç... | Pain | <sec id="s0005"><label>1</label><title>Introduction</title><p id="p0005">Cold temperatures can be refreshing and relieving, but can also evoke sensations of aching, burning, and pricking. Disturbances in cold sensitivity are a feature of a range of neuropathic conditions including complex regional pain syndrome, chemot... |
Deletion and deletion/insertion mutations in the juxtamembrane domain of the <italic>FLT3</italic> gene in adult acute myeloid leukemia | <p>In contrast to <italic>FLT3</italic> ITD mutations, in-frame deletions in the <italic>FLT3</italic> gene have rarely been described in adult acute leukemia. We report two cases of AML with uncommon in-frame mutations in the juxtamembrane domain of the <italic>FLT3</italic> gene: a 3-bp (c.1770_1774delCTACGinsGT; p.F... | <contrib contrib-type="author"><name><surname>Deeb</surname><given-names>Kristin K.</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author"><name><surname>Smonskey</surname><given-names>Matthew T.</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><c... | Leukemia Research Reports | <sec sec-type="intro" id="s0005"><label>1</label><title>Introduction</title><p>Mutations in the <italic>FLT3</italic> gene have been described in about 25% of acute myeloid leukemia (AML). They are somewhat more common in acute promyelocytic leukemia (APL), and have been associated with an increased risk of relapse, de... |
An unusual case of splenomegaly and increased lactate dehydrogenase heralding acute myeloid leukemia with eosinophilia and RUNX1–MECOM fusion transcripts | <p>We report the first case of acute myeloid leukemia (AML) with RUNX1–MECOM fusion transcripts, showing marked eosinophilia. A 63-year old man admitted in August 2013, had previously been observed in April 2013, because of persisting homogeneous splenomegaly and increased LDH, which were initially attributed t... | <contrib contrib-type="author"><name><surname>Forghieri</surname><given-names>Fabio</given-names></name><email>fabio.forghieri@unimore.it</email><xref rid="cor1" ref-type="corresp">⁎</xref></contrib><contrib contrib-type="author"><name><surname>Bigliardi</surname><given-names>Sara</given-names></name></contrib>... | Leukemia Research Reports | <p>The t(3;21)(q26;q22) is a rare cytogenetic abnormality, reported in approximately 1% of all myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) cases and mainly occurring in therapy-related myeloid neoplasms, in accelerated or blast phase of chronic myeloid leukemia or other myeloproliferative neoplasms (... |
Pathogenicity study in sheep using reverse-genetics-based reassortant bluetongue viruses | Could not extract abstract | <contrib contrib-type="author" id="aut0005"><name><surname>Celma</surname><given-names>Cristina C.</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Bhattacharya</surname><given-names>Bishnupriya</given-names></name><xref rid="aff0005" re... | Veterinary Microbiology | <sec id="sec0005"><label>1</label><title>Introduction</title><p id="par0020">Bluetongue (BT), an insect-transmitted, non-contagious viral disease of domestic and wild ruminants is caused by bluetongue virus (BTV). The disease is characterized by inflammation of the mucous membranes, congestion, swelling, hemorrhages an... |
The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT<sub>3</sub>A and 5-HT<sub>3</sub>AB receptors | Could not extract abstract | <contrib contrib-type="author" id="au1"><name><surname>Thompson</surname><given-names>Andrew J.</given-names></name><xref rid="aff2" ref-type="aff">b</xref></contrib><contrib contrib-type="author" id="au2"><name><surname>Verheij</surname><given-names>Mark H.P.</given-names></name><xref rid="aff1" ref-type="aff">a</xref... | Neuropharmacology | <sec id="sec1"><label>1</label><title>Introduction</title><p id="p0035">5-HT<sub>3</sub> receptors are transmembrane ligand-gated ion-channels that are responsible for fast synaptic neurotransmission in the central and peripheral nervous systems. They are composed of five subunits, each of which contains an extracellul... |
Real-time use of instantaneous wave–free ratio: Results of the ADVISE <italic>in-practice</italic>: An international, multicenter evaluation of instantaneous wave–free ratio in clinical practice | Could not extract abstract | <contrib contrib-type="author" id="au0005"><name><surname>Petraco</surname><given-names>Ricardo</given-names></name><degrees>MD</degrees><xref rid="af0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="au0010"><name><surname>Al-Lamee</surname><given-names>Rasha</given-names></name><degrees>MBBS</d... | American Heart Journal | <p id="p0005">The instantaneous wave–free ratio (iFR) is a recently proposed index of coronary disease severity, which uses a trans-lesional pressure ratio as a measure of functional stenosis severity. It can be calculated using conventional pressure guide wires and differs fundamentally from fractional flow re... |
Measuring Recovery Related Outcomes: A Psychometric Investigation of the Recovery Markers Inventory | Could not extract abstract | <contrib contrib-type="author"><name><surname>Lusczakoski</surname><given-names>Kate DeRoche</given-names></name><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Olmos-Gallo</surname><given-names>P. Antonio</given-names></name><address><email>Antonio.Olmos@du.edu</email></address... | Community Mental Health Journal | <p>Spurred by increased interest of members of consumer advocacy groups and recent political influence, professionals in the field of community mental health have undertaken a systemic transformation in order to incorporate the ideas and concepts that facilitate consumers’ recovery (Olmos-Gallo et al. <xref ref... |
False and true pre-treatment predictors of weight loss in obese patients starting a program for lifestyle change | Could not extract abstract | <contrib contrib-type="author"><name><surname>Cresci</surname><given-names>Barbara</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Pala</surname><given-names>Laura</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-t... | Eating and Weight Disorders | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>Weight loss programs for obese patients, particularly those lifestyle change-oriented and without any pharmacological treatment, are known to be time consuming and usually show low percentages of success in terms of weight loss for a relevant number o... |
Eating behavior and perception of body shape in Japanese university students | Could not extract abstract | <contrib contrib-type="author"><name><surname>Ohara</surname><given-names>Kumiko</given-names></name><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Kato</surname><given-names>Yoshiko</given-names></name><xref ref-type="aff" rid="Af... | Eating and Weight Disorders | <sec id="Sec1"><title>Introduction</title><p>It is well known that many girls and women around the world feel driven to remain or become thin. Studies of large populations found that the mean body mass index (BMI) of many young females in European countries and the united States is >25 (overweight) [<xref ref-t... |
Dissecting conformational contributions to glycosidase catalysis and inhibition | Could not extract abstract | <contrib contrib-type="author" id="aut0005"><name><surname>Speciale</surname><given-names>Gaetano</given-names></name><xref rid="aff0005" ref-type="aff">1</xref></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Thompson</surname><given-names>Andrew J</given-names></name><xref rid="aff0010" ref-type="... | Current Opinion in Structural Biology | <p id="par0070">
<boxed-text id="tb0005"><p id="par0025"><bold>Current Opinion in Structural Biology</bold> 2014, <bold>28</bold>:1–13</p><p id="par0030">This review comes from a themed issue on <bold>Carbohydrate-protein interactions and glycosylation</bold></p><p id="par0035">Edited by <bold>Harry J Gilbert</... |
Characterization of the contributions of Hp-MMP 9 to the serum acute phase protein response of lipopolysaccharide challenged calves | Could not extract abstract | <contrib contrib-type="author"><name><surname>Hinds</surname><given-names>Charles A</given-names></name><address><email>ahinds@uidaho.edu</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff4"/></contrib><contrib contrib-type="author"><name><surname>Niehaus</surname><given-names>Andrew J</giv... | BMC Veterinary Research | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Bovine respiratory disease (BRD) and other acute inflammatory diseases have major impacts on livestock productivity. Recent reports indicate the incidence of BRD morbidity in large feedlots is approximately 5-11% and mortality attributed to BRD is appro... |
Violations of local stochastic independence exaggerate scalability in Mokken scaling analysis of the Chinese Mandarin SF-36 | Could not extract abstract | <contrib contrib-type="author"><name><surname>Watson</surname><given-names>Roger</given-names></name><address><email>r.watson@hull.ac.uk</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Wenru</given-names></name><address><email>nurww@nu... | Health and Quality of Life Outcomes | <sec id="Sec1" sec-type="introduction"><title>Background</title><sec id="Sec2"><title>Local stochastic independence</title><p>Questionnaires are commonly used to measure quality of life and a prime example is the Short Form 36-item health survey (SF-36). Questionnaires are comprised of a series of questions, commonly r... |
Lactose-free milk prolonged endurance capacity in lactose intolerant Asian males | Could not extract abstract | <contrib contrib-type="author"><name><surname>Sudsa-ard</surname><given-names>Kriyot</given-names></name><address><email>neo-one13@hotmail.com</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Kijboonchoo</surname><given-names>Kallaya</given-names></... | Journal of the International Society of Sports Nutrition | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>Nutrition is one aspect of an athlete’s lifestyle that can be modified to enhance sporting performance. This encompasses individualized interventions adopted before, during, and after exercise. Appropriate nutrition after exercise can enhance ... |
Genome-wide profiling of mouse RNA secondary structures reveals key features of the mammalian transcriptome | Could not extract abstract | <contrib contrib-type="author"><name><surname>Incarnato</surname><given-names>Danny</given-names></name><address><email>danny.incarnato@hugef-torino.org</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/></contrib><contrib contrib-type="author"><name><surname>Neri</surname><given-names>F... | Genome Biology | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>The development of high-throughput methods for the analysis of the epigenome and transcriptome have led to the discovery of thousands of previously unannotated transcripts [<xref ref-type="bibr" rid="CR1">1</xref>,<xref ref-type="bibr" rid="CR2">2</xref... |
Acute diarrhea in adults consulting a general practitioner in France during winter: incidence, clinical characteristics, management and risk factors | Could not extract abstract | <contrib contrib-type="author" corresp="yes" deceased="no" equal-contrib="no"><name><surname>Arena</surname><given-names>Christophe</given-names></name><address><email>christophe.arena@upmc.fr</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/><xref ref-type="aff" rid="Aff3"/></contrib><... | BMC Infectious Diseases | <sec id="Sec1"><title>Background</title><p>In industrialized countries, acute diarrhea (AD) is a major cause of morbidity and medical expenses, particularly in vulnerable populations, such as elderly patients who are more often hospitalized, stay in the hospital longer and die more often than younger individuals when A... |
Factors associated with healthcare avoidance among transgender women in Argentina | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Socías</surname><given-names>María Eugenia</given-names></name><address><email>eugenia.socias@huesped.org.ar</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Marshall</surname><given-name... | International Journal for Equity in Health | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>Transgender (TG) women, the term for individuals who were assigned male sex at birth, but assume a feminine gender expression or identity, often experience multiple forms of oppression for transgressing gender norms, such as stigma, discrimination, is... |
Genome-wide analysis of <italic>Cyclophilin</italic> gene family in soybean (<italic>Glycine max</italic>) | Could not extract abstract | <contrib contrib-type="author"><name><surname>Mainali</surname><given-names>Hemanta Raj</given-names></name><address><email>hemanta.mainali@agr.gc.ca</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Chapman</surname><given-names>Patrick</given-names></name><addre... | BMC Plant Biology | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Cyclophilins (CYPs) are ubiquitous proteins found in organisms ranging from archaea and bacteria to plants and animals [<xref ref-type="bibr" rid="CR1">1</xref>,<xref ref-type="bibr" rid="CR2">2</xref>]. As they were originally identified as receptors f... |
Stroke, multimorbidity and polypharmacy in a nationally representative sample of 1,424,378 patients in Scotland: implications for treatment burden | Could not extract abstract | <contrib contrib-type="author"><name><surname>Gallacher</surname><given-names>Katie I</given-names></name><address><email>katie.gallacher@glasgow.ac.uk</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Batty</surname><given-names>G David</given-names></name><addre... | BMC Medicine | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Multimorbidity, defined as the presence of two or more long-term conditions, is becoming a global challenge for policy-makers, clinicians, and patients [<xref ref-type="bibr" rid="CR1">1</xref>-<xref ref-type="bibr" rid="CR3">3</xref>]. Treatment advanc... |
Primary care treatment guidelines for skin infections in Europe: congruence with antimicrobial resistance found in commensal <italic>Staphylococcus aureus</italic> in the community | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>van Bijnen</surname><given-names>Evelien ME</given-names></name><address><email>e.vanbijnen@nivel.nl</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Paget</surname><given-names>W John</given-names></nam... | BMC Family Practice | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Antimicrobial resistance (AMR) has become an important public health threat across the globe during recent decades [<xref ref-type="bibr" rid="CR1">1</xref>–<xref ref-type="bibr" rid="CR3">3</xref>]. The development of AMR is considered to be ma... |
Barriers to the implementation of mobile phone reminders in pediatric HIV care: a pre-trial analysis of the Cameroonian MORE CARE study | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Bigna</surname><given-names>Jean Joel R</given-names></name><address><email>bignarimjj@yahoo.fr</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/><xref ref-type="aff" rid="Aff3"/></contrib><contrib contrib-type="author"><name><... | BMC Health Services Research | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>The Global Observatory for eHealth defines mobile health (mHealth) as medical and public health practice supported by mobile devices, such as mobile phones, patient monitoring devices, personal digital assistants, and other wireless devices [<xref ref-t... |
Barriers and facilitators to using NHS Direct: a qualitative study of ‘users’ and ‘non-users’ | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Cook</surname><given-names>Erica J</given-names></name><address><email>erica.cook@beds.ac.uk</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Randhawa</surname><given-names>Gurch</given-names></name><add... | BMC Health Services Research | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>In 2012, NHS Direct was replaced with the new non-emergency ‘111’ telephone-based healthcare service. It was first introduced in 2010, followed by a national rollout in 2013. The aim was to provide a more integrated non-emergency service... |
Ovarian metastasis from thyroid carcinoma: a case report and literature review | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Corrado</surname><given-names>Giacomo</given-names></name><address><email>giacomo.corrado@alice.it</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Pomati</surname><given-names>Giulia</given-names></name... | Diagnostic Pathology | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Papillary thyroid carcinoma is the most common histotype of thyroid carcinoma and it is associated to a good prognosis and to a loco regional spread. The presence of distant metastasis is an important prognostic factor, although it is a rare event. Dist... |
Del Nido Cardioplegia can be safely administered in high-risk coronary artery bypass grafting surgery after acute myocardial infarction: a propensity matched comparison | Could not extract abstract | <contrib contrib-type="author" deceased="no" equal-contrib="no"><name><surname>Yerebakan</surname><given-names>Halit</given-names></name><address><email>drhalid@gmail.com</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author" deceased="no" equal-contrib="no"><name><surname>Sorabella<... | Journal of Cardiothoracic Surgery | <sec id="Sec1"><title>Background</title><p>Despite advances in surgical technique and patient selection, mortality after coronary artery bypass grafting surgery (CABG) for acute myocardial infarction (AMI) remains high at 4-10% [<xref ref-type="bibr" rid="CR1">1</xref>],[<xref ref-type="bibr" rid="CR2">2</xref>]. Myoca... |
Video-confidence: a qualitative exploration of videoconferencing for psychiatric emergencies | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Trondsen</surname><given-names>Marianne Vibeke</given-names></name><address><email>marianne.trondsen@telemed.no</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Bolle</surname><given-names>Stein Roald</g... | BMC Health Services Research | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>De-institutionalisation, in the form of providing patient services through outpatient clinics and day treatment rather than hospital stays, is a strong and growing trend in healthcare services. In psychiatric hospitals, this process began in the 1960s a... |
Significance of ossificated ungular cartilages regarding the performance of cold-blooded trotters | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Hedenström</surname><given-names>Ulf O</given-names></name><address><email>ulf.hedenstrom@wangen.se</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Wattle</surname><given-names>Ove S</given-name... | Acta Veterinaria Scandinavica | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Ossification of the ungular cartilages (OUC) in the foot of horses has been studied in different breeds for more than 100 years and the high heritability of this condition is well known [<xref ref-type="bibr" rid="CR1">1</xref>-<xref ref-type="b... |
Observational study to characterise 24-hour COPD symptoms and their relationship with patient-reported outcomes: results from the ASSESS study | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Miravitlles</surname><given-names>Marc</given-names></name><address><email>mmiravitlles@vhebron.net</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Worth</surname><given-names>Heinrich</given-names></na... | Respiratory Research | <sec id="Sec1"><title>Background</title><p>Despite being preventable and treatable, chronic obstructive pulmonary disease (COPD) is associated with considerable morbidity and mortality [<xref ref-type="bibr" rid="CR1">1</xref>,<xref ref-type="bibr" rid="CR2">2</xref>] and its prevalence is expected to increase in the c... |
Improving the accuracy of expression data analysis in time course experiments using resampling | Could not extract abstract | <contrib contrib-type="author"><name><surname>Walter</surname><given-names>Wencke</given-names></name><address><email>wwalter@cnic.es</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Striberny</surname><given-names>Bernd</given-names></name><address><email>bernd.... | BMC Bioinformatics | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Even with decreasing costs for sequencing and microarray experiments, time series experiments are still expensive and require a large number of samples. Thus, most time series currently have a very limited number of biological replicates. This makes it ... |
Feasibility and effectiveness of drop-off spots to promote walking to school | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Vanwolleghem</surname><given-names>Griet</given-names></name><address><email>Griet.Vanwolleghem@Ugent.be</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>D’Haese</surname><given-names>Sara</given... | The International Journal of Behavioral Nutrition and Physical Activity | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Engaging in walking and cycling to school is an important source of daily physical activity in 6-to-12-year olds [<xref ref-type="bibr" rid="CR1">1</xref>-<xref ref-type="bibr" rid="CR3">3</xref>]. Despite the numerous health benefits of active transpor... |
Comparison of trace element concentration in bone and intervertebral disc tissue by atomic absorption spectrometry techniques | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Kubaszewski</surname><given-names>Łukasz</given-names></name><address><email>pismiennictwo1@gmail.com</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff4"/></contrib><contrib contrib-type="author"><name><surname>Zioł... | Journal of Orthopaedic Surgery and Research | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Trace element (TE) analysis in biota has a twofold purpose of monitoring environmental exposure to the pollutants and, secondarily, of indirect analysis of metabolism-related issues. The human body can be divided into several compartments with respect t... |
Early activation of pro-fibrotic WNT5A in sepsis-induced acute lung injury | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Villar</surname><given-names>Jesús</given-names></name><address><email>jesus.villar54@gmail.com</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/><xref ref-type="aff" rid="Aff3"/></contrib><contrib contrib-type="author"... | Critical Care | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>Acute respiratory distress syndrome (ARDS) is a severe inflammatory process caused by pulmonary or systemic insults to the lung alveolar-capillary barrier [<xref ref-type="bibr" rid="CR1">1</xref>-<xref ref-type="bibr" rid="CR3">3</xref>]. Sepsis is t... |
A comparison of principal component regression and genomic REML for genomic prediction across populations | Could not extract abstract | <contrib contrib-type="author"><name><surname>Dadousis</surname><given-names>Christos</given-names></name><address><email>christos.dadousis@studenti.unipd.it</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/></contrib><contrib contrib-type="author"><name><surname>Veerkamp</surname><give... | Genetics, Selection, Evolution : GSE | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>For many years, dairy cattle breeding programs have been very successful in identifying the best animals via progeny-testing schemes. Progeny-testing was first implemented in Denmark and was soon used all over the world [<xref ref-type="bibr" rid="CR1">... |
Along with the privilege of authorship come important responsibilities | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Moher</surname><given-names>David</given-names></name><address><email>dmoher@ohri.ca</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/></contrib><aff id="Aff1"><label/>Knowledge Synthesis Group, Clinical Epidemiology Program, O... | BMC Medicine | <sec id="Sec1"><title>Commentary</title><p>“<italic>Complexity is the enemy of transparency</italic>” [<xref ref-type="bibr" rid="CR1">1</xref>]. Today, <italic>BMC Medicine</italic> publishes another paper on journalology (publication science) [<xref ref-type="bibr" rid="CR2">2</xref>]. Attributing aut... |
Myofibroblastic reaction is a common event in metastatic disease of breast carcinoma: a descriptive study | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Catteau</surname><given-names>Xavier</given-names></name><address><email>xavier.catteau06@gmail.com</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/><xref ref-type="aff" rid="Aff5"/></contrib><contrib contrib-type="author"><na... | Diagnostic Pathology | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>The importance of the stromal microenvironment has been suggested to play a major role in breast carcinoma by promoting tumour growth, progression and invasion [<xref ref-type="bibr" rid="CR1">1</xref>-<xref ref-type="bibr" rid="CR4">4</xref>]. In parti... |
Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Lönnstedt</surname><given-names>Ingrid M</given-names></name><address><email>ingrid.lonnstedt@gmail.com</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/><xref ref-type="aff" rid="Aff3"/></contrib><contrib contrib-type=... | Genome Biology | <sec id="Sec1" sec-type="introduction"><title>Background</title><p>Genomes can vary between cells within a tumor. Mutations and copy number (CN) alterations which appear during tumor development result in genomic subclones emerging. Subclonality of tumors is referred to as intra-tumor heterogeneity (ITH), a topic which... |
Tanshinone II-A sodium sulfonate (DS-201) enhances human BK<sub>Ca</sub> channel activity by selectively targeting the pore-forming α subunit | <sec><title>Aim:</title><p>Tanshinone II-A sodium sulfonate (DS-201), a water-soluble derivative of Tanshinone II-A, has been found to induce vascular relaxation and activate BK<sub>Ca</sub> channels. The aim of this study was to explore the mechanisms underlying the action of DS-201 on BK<sub>Ca</sub> channels.</p></s... | <contrib contrib-type="author"><name><surname>Tan</surname><given-names>Xiao-qiu</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="author-notes" rid="note1"><sup>#</sup></xref></contrib><contrib contrib-type="author"><name><surname>Cheng</surname... | Acta Pharmacologica Sinica | <sec sec-type="intro"><title>Introduction</title><p>It is well known that arterial tone is regulated by functional balance of the ion channels responsible for cellular depolarization and hyperpolarization<sup><xref ref-type="bibr" rid="bib1">1</xref></sup>. The large conductance calcium-activated potassium channels (BK... |
Interest of low-dose hydrocortisone therapy during brain-dead organ donor resuscitation: the CORTICOME study | Could not extract abstract | <contrib contrib-type="author"><name><surname>Pinsard</surname><given-names>Michel</given-names></name><address><email>Michel.Pinsard@chu-poitiers.fr</email></address><xref ref-type="aff" rid="Aff69"/></contrib><contrib contrib-type="author"><name><surname>Ragot</surname><given-names>Stéphanie</given-names></na... | Critical Care | <sec id="Sec1" sec-type="intro"><title>Introduction</title><p>Currently in France, increasing transplantation indications cannot be met because of graft shortage. It has been proven that the amount of procured grafts can be increased by an optimized management of brain-dead patients [<xref ref-type="bibr" rid="CR1">1</... |
Modeling the economic impact of linezolid versus vancomycin in confirmed nosocomial pneumonia caused by methicillin-resistant <italic>Staphylococcus aureus</italic> | <sec><title>Introduction</title><p>We compared the economic impacts of linezolid and vancomycin for the treatment of hospitalized patients with methicillin-resistant <italic>Staphylococcus aureus</italic> (MRSA)–confirmed nosocomial pneumonia.</p></sec><sec><title>Methods</title><p>We used a 4-week decision tre... | <contrib contrib-type="author" id="A1"><name><surname>Patel</surname><given-names>Dipen A</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>dpatel@pharmerit.com</email></contrib><contrib contrib-type="author" id="A2"><name><surname>Shorr</surname><given-names>Andrew F</given-names></name><xref ref-type="... | Critical Care | <sec sec-type="intro"><title>Introduction</title><p>Nosocomial pneumonia (NP) has been reported to be the second most frequent hospital-acquired infection in the United States [<xref ref-type="bibr" rid="B1">1</xref>]. Methicillin-resistant <italic>Staphylococcus aureus</italic> (MRSA) is responsible for a large number... |
<sup>18</sup> F-Fluoride positron emission tomography/computed tomography for noninvasive <italic>in vivo</italic> quantification of pathophysiological bone metabolism in experimental murine arthritis | <sec><title>Introduction</title><p>Evaluation of disease severity in experimental models of rheumatoid arthritis is inevitably associated with assessment of structural bone damage. A noninvasive imaging technology allowing objective quantification of pathophysiological alterations of bone structure in rodents could sub... | <contrib contrib-type="author" corresp="yes" id="A1"><name><surname>Irmler</surname><given-names>Ingo M</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>ingo.irmler@med.uni-jena.de</email></contrib><contrib contrib-type="author" id="A2"><name><surname>Gebhardt</surname><given-names>Peter</given-names></... | Arthritis Research & Therapy | <sec sec-type="intro"><title>Introduction</title><p>Rheumatoid arthritis (RA) is one of the most common autoimmune diseases, affecting approximately 1% of the population in Europe and North America. Bone erosion can be detected as early as several weeks after the onset of the first clinical signs and symptoms of RA
[<x... |
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression | Could not extract abstract | <contrib contrib-type="author"><name><surname>Chen</surname><given-names>Jing-Yi</given-names></name><address><email>e3336685@yahoo.com.tw</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Li</surname><given-names>Chien-Feng</given-names></name><address><em... | Breast Cancer Research : BCR | <sec id="Sec1"><title>Background</title><p>Chronic inflammation is strongly associated with the development of cancer [<xref ref-type="bibr" rid="CR1">1</xref>]-–[<xref ref-type="bibr" rid="CR3">3</xref>]. One of the crucial mediators of inflammatory reaction is cyclooxygenase (COX). The COX family of enzymes c... |
Nestin positively regulates the Wnt/β-catenin pathway and the proliferation, survival and invasiveness of breast cancer stem cells | Could not extract abstract | <contrib contrib-type="author"><name><surname>Zhao</surname><given-names>Zuowei</given-names></name><address><email>dlzhaozw@163.com</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Lu</surname><given-names>Ping</given-names></name><address><email>luping29... | Breast Cancer Research : BCR | <sec id="Sec1"><title>Introduction</title><p>Breast cancer is the most common malignancy in women, and its incidence is increasing worldwide. The disease remains a huge threat to women’s health. Patients with ‘triple-negative’ breast cancer, referring to absence in the expression of estrogen rec... |
Use of <sup>1</sup>H-nuclear magnetic resonance to screen a set of biomarkers for monitoring metabolic disturbances in severe burn patients | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Zhang</surname><given-names>Yong</given-names></name><address><email>zhangyong79@tmmu.edu.cn</email></address><xref ref-type="aff" rid="Aff10"/></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Cai</surname><given-names>Bin</given-names></n... | Critical Care | <sec id="Sec1" sec-type="intro"><title>Introduction</title><p>Burn is a common injury with an incidence of about 0.2% in the normal population. Every year, approximately 3 million people in China and 0.8 million in the United States suffer from burns, with 200,000 and 40,000 requiring hospitalization, respectively [<xr... |
Targeting IL-6 by both passive or active immunization strategies prevents bleomycin-induced skin fibrosis | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Desallais</surname><given-names>Lucille</given-names></name><address><email>lucille.desallais@gmail.com</email></address><xref ref-type="aff" rid="Aff67"/></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Avouac</surname><given-names>J�... | Arthritis Research & Therapy | <sec id="Sec1" sec-type="intro"><title>Introduction</title><p>Systemic sclerosis (SSc, scleroderma) is a connective tissue disease of unknown etiology that affects particularly the skin. Early stages of SSc are characterized by vascular changes and inflammatory infiltrates in the lesional skin [<xref ref-type="bibr" ri... |
Broadening horizons: holistic viewpoints from the Biology of Genomes | <p>A report on the Cold Spring Harbor Laboratory 27th annual meeting on the Biology of Genomes, held in Cold Spring Harbor, New York, USA, 6-10 May 2014.</p> | <contrib contrib-type="author" id="A1"><name><surname>Carr</surname><given-names>Ambrose</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>ajc2205@columbia.edu</email></contrib><contrib contrib-type="author" corresp="yes" id="A2"><name><surname>Pe’er</surname><given-names>Dana</given-names></name... | Genome Biology | <sec><title>Fine mapping in <italic>cis</italic> discovers substantial functional regulatory variation</title><p>‘Biology of Genomes’ is a broad annual meeting that showcases the year’s progress in the many subfields of genomics. With so many talks, it is impossible to cover all of them. However... |
How to manage aspergillosis in non-neutropenic intensive care unit patients | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Bassetti</surname><given-names>Matteo</given-names></name><address><email>mattba@tin.it</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Righi</surname><given-names>Elda</given-names></name><address><ema... | Critical Care | <sec id="Sec1"><title>Review</title><sec id="Sec2" sec-type="introduction"><title>Introduction</title><p>Invasive aspergillosis (IA) is an opportunistic infection that occurs mainly among patients with hematological malignancies, most notably during prolonged periods of neutropenia, but also in subjects with solid tumo... |
Psychometric comparison of three behavioural scales for the assessment of pain in critically ill patients unable to self-report | Could not extract abstract | <contrib contrib-type="author"><name><surname>Chanques</surname><given-names>Gerald</given-names></name><address><email>g-chanques@chu-montpellier.fr</email></address><xref ref-type="aff" rid="Aff1"/><xref ref-type="aff" rid="Aff2"/><xref ref-type="aff" rid="Aff3"/></contrib><contrib contrib-type="author"><name><surnam... | Critical Care | <sec id="Sec1" sec-type="intro"><title>Introduction</title><p>Pain is a frequent event in Intensive Care Unit (ICU) patients, with an incidence of up to 50% in medical as well as surgical patients
[<xref ref-type="bibr" rid="CR1">1</xref>–<xref ref-type="bibr" rid="CR3">3</xref>]. Pain is associated with an acu... |
Experimental and clinical evidences for glucose control in intensive care: is infused glucose the key point for study interpretation? | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Mazeraud</surname><given-names>Aurélien</given-names></name><address><email>aurelien.mazeraud@pasteur.fr</email></address><xref ref-type="aff" rid="Aff31"/><xref ref-type="aff" rid="Aff32"/></contrib><contrib contrib-type="author" corresp="yes"><name><... | Critical Care | <sec id="Sec1" sec-type="intro"><title>Introduction</title><p>In an ICU, stress induces insulin resistance and overproduction of glucose, resulting in a syndrome called stress-induced hyperglycemia (SIH) [<xref ref-type="bibr" rid="CR1">1</xref>]. SIH is common during critical illness and is associated with high mortal... |
Chipping away at major depressive disorder | <p>An intriguing recent study examines the role of miR-1202, a glutamate receptor regulating microRNA, in regulating major depressive disorder.</p> | <contrib contrib-type="author" corresp="yes" id="A1"><name><surname>Rucker</surname><given-names>James JH</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>james.rucker@kcl.ac.uk</email></contrib><contrib contrib-type="author" id="A2"><name><surname>McGuffin</surname><given-names>Peter</given-names></nam... | Genome Biology | <sec><title>The challenge of major depressive disorder</title><p>Major depressive disorder (MDD), a common, yet debilitating and economically costly, psychiatric disorder [[<xref ref-type="bibr" rid="B1">1</xref>]], has proven surprisingly refractory to molecular-genetic investigation and the development of biomarkers ... |
Have plants evolved to self-immolate? | <p>By definition fire prone ecosystems have highly combustible plants, leading to the hypothesis, first formally stated by Mutch in 1970, that community flammability is the product of natural selection of flammable traits. However, proving the “Mutch hypothesis” has presented an enormous challenge for f... | <contrib contrib-type="author"><name><surname>Bowman</surname><given-names>David M. J. S.</given-names></name><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/137024"/></contrib><contrib contrib-type="author"><name><surname>French</surname><given-names>Ben J.</given-names></name><uri xlink... | Frontiers in Plant Science | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>The combination of carbon rich biomass, atmospheric oxygen, and ignitions makes landscape fire inevitable on Earth (Bowman et al., <xref rid="B14" ref-type="bibr">2009</xref>). However, the occurrence, spread, and energy released by landscape fires is c... |
Heterologous over-expression of <italic>ACC SYNTHASE8 (ACS8)</italic> in <italic>Populus tremula x P. alba</italic> clone 717-1B4 results in elevated levels of ethylene and induces stem dwarfism and reduced leaf size through separate genetic pathways | <p>Plant height is an important agronomic and horticultural trait that impacts plant productivity, durability and esthetic appeal. A number of the plant hormones such as gibberellic acid (GA), auxin and ethylene have been linked to control of plant architecture and size. Reduction in GA synthesis and auxin transport re... | <contrib contrib-type="author"><name><surname>Plett</surname><given-names>Jonathan M.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/98537"/></contrib><contrib contri... | Frontiers in Plant Science | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>Reduced plant height, or dwarfism, is an important agronomic trait linked to higher yields (Huang et al., <xref rid="B37" ref-type="bibr">1996</xref>; Yang and Hwa, <xref rid="B90" ref-type="bibr">2008</xref>), easier harvesting (Adkins et al., <xref ri... |
Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction | <p>Circadian clock mechanisms are far-from-equilibrium dissipative structures. Peroxisome proliferator-activated receptors (PPAR alpha, beta/delta, and gamma) play a key role in metabolic regulatory processes, particularly in heart muscle. Links between circadian rhythms (CRs) and PPARs have been established. Mammalian... | <contrib contrib-type="author"><name><surname>Lecarpentier</surname><given-names>Yves</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="author-notes" rid="fn001"><sup>*</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/139386"/></contrib><con... | Frontiers in Physiology | <sec sec-type="intro" id="s1"><title>Introduction</title><p>CRs are biological temporal processes that display endogenous, entrainable free-running periods that last approximately 24 h. They are driven by molecular internal clocks which can be reset by environmental light-dark cycles. Circadian clocks are transcription... |
Animal Models to Investigate the Pathogenesis of Rheumatic Heart Disease | <p>Rheumatic fever (RF) and rheumatic heart disease (RHD) are sequelae of group A streptococcal (GAS) infection. Although an autoimmune process has long been considered to be responsible for the initiation of RF/RHD, it is only in the last few decades that the mechanisms involved in the pathogenesis of the inflammatory... | <contrib contrib-type="author"><name><surname>Rush</surname><given-names>Catherine M.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Govan</surname><given-names>Brenda L.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xre... | Frontiers in Pediatrics | <sec sec-type="intro" id="S1"><title>Introduction</title><p>Animal experimentation has been used for centuries to better understand human physiology and pathological processes, to improve diagnosis and to develop safe intervention, treatment, and prevention strategies. References to animal experimentation are found in ... |
IPM thresholds for <italic>Agriotes</italic> wireworm species in maize in Southern Europe | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Furlan</surname><given-names>Lorenzo</given-names></name><address><phone>+39-049-8293879</phone><fax>+39-049-8293815</fax><email>lorenzo.furlan@venetoagricoltura.org</email></address><xref ref-type="aff" rid="Aff1"/></contrib><aff id="Aff1">Veneto Agricoltura,... | Journal of Pest Science | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>EU Directive 2009/128/EC on the sustainable use of pesticides makes it compulsory to implement integrated pest management (IPM) for annual crops in Europe from January 2014. IPM strategies have not played a significant role in these crops to date, yet... |
Insights into Genetic and Epigenetic Determinants with Impact on Vitamin D Signaling and Cancer Association Studies: The Case of Thyroid Cancer | <p>Vitamin D is a key regulator of calcium metabolism and has been implicated as a cancer preventive agent. However, clinical studies have revealed conflicting results on its cancer preventive properties, attributed in part to multiple metabolic and regulatory factors susceptible to affect individual responses to exoge... | <contrib contrib-type="author"><name><surname>Morand</surname><given-names>Grégoire B.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/184739"/></contrib><contrib contri... | Frontiers in Oncology | <sec sec-type="introduction" id="S1"><title>Introduction</title><p>Thyroid cancer (TC) is the most common endocrine cancer malignancy worldwide (<xref rid="B1" ref-type="bibr">1</xref>) with a rising incidence in particular among young patients and women (<xref rid="B2" ref-type="bibr">2</xref>–<xref rid="B4" r... |
The obesity paradox in acute coronary syndrome: a meta-analysis | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Niedziela</surname><given-names>Jacek</given-names></name><address><phone>+48 32 3733619</phone><email>jacek@niedziela.org</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Hudzik</surname><given-n... | European Journal of Epidemiology | <sec id="Sec1"><title>Background</title><p>The concept of obesity (from the Latin word obdere—to eat all over: ob—over, above; edere—to eat) for the first time was used in the Oxford Dictionary in 1611, as a synonym for words: corpulent, thick [<xref ref-type="bibr" rid="CR1">1</xref>]. The olde... |
Supporting Pregnant Aboriginal and Torres Strait Islander Women to Quit Smoking: Views of Antenatal Care Providers and Pregnant Indigenous Women | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Passey</surname><given-names>Megan E.</given-names></name><address><email>megan.passey@ucrh.edu.au</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Sanson-Fisher</surname><given-names>Rob W.</give... | Maternal and Child Health Journal | <sec id="Sec1"><title>Introduction</title><p>Tobacco smoking among pregnant Aboriginal and Torres Strait Islander women remains three times as common as among non-Indigenous Australian pregnant women, with approximately 50 % of women smoking during pregnancy [<xref ref-type="bibr" rid="CR1">1</xref>]. Addressin... |
Interleukin-2-Inducible T-Cell Kinase (ITK) Deficiency - Clinical and Molecular Aspects | Could not extract abstract | <contrib contrib-type="author"><name><surname>Ghosh</surname><given-names>Sujal</given-names></name><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Bienemann</surname><given-names>Kirsten</given-names></name><xref ref-type="aff" rid... | Journal of Clinical Immunology | <sec id="Sec1" sec-type="introduction"><title>Background</title><p id="Par2">Epstein-Barr virus (EBV), being one of the most common viruses in humans, is best known to cause infectious mononucleosis. In patients with underlying immunodeficiency, EBV may lead to severe immune dysregulation manifesting as fatal mononucle... |
The Activation of the Sox2 RR2 Pluripotency Transcriptional Reporter in Human Breast Cancer Cell Lines is Dynamic and Labels Cells with Higher Tumorigenic Potential | <p>The striking similarity displayed at the mechanistic level between tumorigenesis and the generation of induced pluripotent stem cells and the fact that genes and pathways relevant for embryonic development are reactivated during tumor progression highlights the link between pluripotency and cancer. Based on these ob... | <contrib contrib-type="author"><name><surname>Iglesias</surname><given-names>Juan Manuel</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/188095"/></contrib><contrib contrib-type... | Frontiers in Oncology | <sec sec-type="introduction" id="S1"><title>Introduction</title><p>Cancer stem cells (CSCs) play a central role in tumor progression and recurrence, but our knowledge of their biology and origin is still limited. The lack of good CSC markers in solid tumors could explain our limited understanding of its biology and ham... |
Knowledge, Perception and Utilization of Postnatal Care of Mothers in Gondar Zuria District, Ethiopia: A Cross-Sectional Study | Could not extract abstract | <contrib contrib-type="author"><name><surname>Tesfahun</surname><given-names>Fikirte</given-names></name><address><email>seblefikir@yahoo.com</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Worku</surname><given-names>Walelegn</given-names></name><address... | Maternal and Child Health Journal | <sec id="Sec1"><title>Background</title><p>
The health of mothers is mostly regarded as an indicator the health of the society. Globally, more than half a million women die each year from complications of pregnancy and childbirth [<xref ref-type="bibr" rid="CR1">1</xref>–<xref ref-type="bibr" rid="CR3">3</xref>... |
Breastfeeding Practices in Relation to Country of Origin Among Women Living in Denmark: A Population-Based Study | Could not extract abstract | <contrib contrib-type="author"><name><surname>Busck-Rasmussen</surname><given-names>Marianne</given-names></name><address><email>marianne_busck@yahoo.dk</email></address><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Villadsen</surname><given-names>Sarah Fredsted<... | Maternal and Child Health Journal | <sec id="Sec1"><title>Introduction</title><p>The beneficial effect of breastfeeding on infant health is well described, and WHO recommends at least 6 months of exclusive breastfeeding for children globally [<xref ref-type="bibr" rid="CR1">1</xref>]. One of the most important short term effects of breastfeeding ... |
Combined Immunodeficiency Evolving into Predominant CD4+ Lymphopenia Caused by Somatic Chimerism in JAK3 | Could not extract abstract | <contrib contrib-type="author"><name><surname>Ban</surname><given-names>Sol A.</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Salzer</surname><given-names>Elisabeth</given-names></name><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib... | Journal of Clinical Immunology | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p id="Par5">Idiopathic CD4 lymphopenias (ICLs) constitute an enigmatic and heterogeneous group of disorders which are collectively characterized by prolonged low CD4+ T lymphocyte count of less than 300 cells/μl or less than 20 % of lymphocytes ... |
A Community Engagement Process Identifies Environmental Priorities to Prevent Early Childhood Obesity: The Children’s Healthy Living (CHL) Program for Remote Underserved Populations in the US Affiliated Pacific Islands, Hawaii and Alaska | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Fialkowski</surname><given-names>Marie Kainoa</given-names></name><address><phone>+808-956-8337</phone><email>mariekf@hawaii.edu</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>DeBaryshe</surname... | Maternal and Child Health Journal | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>Childhood obesity prevalence and its associated health complications have become a major national and global public health issue. Obese and overweight children are at risk for serious chronic illnesses [<xref ref-type="bibr" rid="CR1">1</xref>–... |
A Multicenter Retrospective Study of Frameless Robotic Radiosurgery for Intracranial Arteriovenous Malformation | <p><bold>Introduction:</bold> CT-guided, frameless radiosurgery is an alternative treatment to traditional catheter-angiography targeted, frame-based methods for intracranial arteriovenous malformations (AVMs). Despite the widespread use of frameless radiosurgery for treating intracranial tumors, its use for treating A... | <contrib contrib-type="author"><name><surname>Oermann</surname><given-names>Eric K.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1">*</xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/40933"/></contrib><contrib contrib-type="author"><na... | Frontiers in Oncology | <sec sec-type="introduction" id="S1"><title>Introduction</title><p>Intracranial arteriovenous malformations (AVMs) present one of the greatest clinical challenges for neurosurgeons, radiation oncologists, and neurointerventionalists. Classically, the treatment of these lesions involved careful patient selection followe... |
Perinatal Distress in Women in Low- and Middle-Income Countries: Allostatic Load as a Framework to Examine the Effect of Perinatal Distress on Preterm Birth and Infant Health | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Premji</surname><given-names>Shahirose</given-names></name><address><phone>+01-403-220-4081</phone><email>premjis@ucalgary.ca</email></address><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff2">2</xref><xref ref-type="aff" rid="Aff3">3</xr... | Maternal and Child Health Journal | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>Both perinatal distress and preterm birth are world-wide problems that are especially burdensome in low- and middle- income countries (LMIC). Maternal prenatal and postnatal distress (i.e., stress, anxiety, or depression at any time in pregnancy and d... |
Maintenance of familiarity and social bonding via communal latrine use in a solitary primate (<italic>Lepilemur leucopus</italic>) | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Dröscher</surname><given-names>Iris</given-names></name><address><phone>++49 551 39 7345</phone><email>iris.droescher@gmail.com</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Kappeler</s... | Behavioral Ecology and Sociobiology | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p id="Par2">Chemical signals can transmit a variety of information in vertebrates, such as species identity (Caspers et al. <xref ref-type="bibr" rid="CR23">2009</xref>), sexual identity (Ferkin and Johnston <xref ref-type="bibr" rid="CR45">1995</xref>)... |
Corrosion current density prediction in reinforced concrete by imperialist competitive algorithm | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Sadowski</surname><given-names>Lukasz</given-names></name><address><email>lukasz.sadowski@pwr.edu.pl</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Nikoo</surname><given-names>Mehdi</given-names... | Neural Computing & Applications | <sec id="Sec1"><title>Introduction</title><p>Reinforced concrete (RC) is one of the most commonly used construction materials in civil engineering industry, and reinforcement corrosion is a major problem. For this reason, inspection techniques are used to evaluate steel corrosion in concrete in order to protect RC stru... |
Colony size, but not density, affects survival and mating success of alternative male reproductive tactics in a polyphenic mite, <italic>Rhizoglyphus echinopus</italic> | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Radwan</surname><given-names>Jacek</given-names></name><address><phone>+48 661641380</phone><email>jradwan@amu.edu.pl</email></address><xref ref-type="aff" rid="Aff1">1</xref><xref ref-type="aff" rid="Aff2">2</xref></contrib><contrib contrib-type="author"><nam... | Behavioral Ecology and Sociobiology | <sec id="Sec1" sec-type="introduction"><title>Introduction</title><p>Alternative reproductive tactics (ARTs) are among the most spectacular examples of discontinuous phenotypic variation within species (reviewed in: Gross <xref ref-type="bibr" rid="CR9">1996</xref>; Brockmann <xref ref-type="bibr" rid="CR1">2001</xref>... |
Queen and young larval pheromones impact nursing and reproductive physiology of honey bee (<italic>Apis mellifera</italic>) workers | Could not extract abstract | <contrib contrib-type="author" corresp="yes"><name><surname>Traynor</surname><given-names>Kirsten S.</given-names></name><address><phone>240-439-3053</phone><email>ktraynor@asu.edu</email></address><xref ref-type="aff" rid="Aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Le Conte</surname><given-n... | Behavioral Ecology and Sociobiology | <p id="Par2">Within social insects, the chemical communication system has proven to be highly diversified and richly complex, enhanced by synergistic interactions and context-dependent messaging (Slessor et al. <xref ref-type="bibr" rid="CR83">2005</xref>). For example, at least 50 substances derived from queens, worke... |
Cell-surface translational dynamics of nicotinic acetylcholine receptors | <p>Synapse efficacy heavily relies on the number of neurotransmitter receptors available at a given time. In addition to the equilibrium between the biosynthetic production, exocytic delivery and recycling of receptors on the one hand, and the endocytic internalization on the other, lateral diffusion and clustering of ... | <contrib contrib-type="author"><name><surname>Barrantes</surname><given-names>Francisco J.</given-names></name><xref ref-type="author-notes" rid="fn002"><sup>*</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/14093"/></contrib> | Frontiers in Synaptic Neuroscience | <sec sec-type="intro"><title>INTRODUCTION</title><p>The nAChR abbreviationαBTX, α-bungarotoxin; CDx, methyl-β-cyclodextrin; FCS, fluorescence correlation spectroscopy; FRAP, fluorescence recovery after photobleaching; MSD, mean square displacement; nAChR, nicotinic acetylcholine receptor; SPT, s... |
Heart Rate Variability Biofeedback Intervention for Reduction of Psychological Stress During the Early Postpartum Period | Could not extract abstract | <contrib contrib-type="author"><name><surname>Kudo</surname><given-names>Naoko</given-names></name><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"><name><surname>Shinohara</surname><given-names>Hitomi</given-names></name><xref ref-type="aff" rid="Aff1"/></contrib><contrib contrib-type="author"... | Applied Psychophysiology and Biofeedback | <sec id="Sec1"><title>Introduction</title><p>Immediately after delivery, mothers are required to adapt to a new lifestyle that focuses on childcare. Many mothers find the process of meeting the demands of their new lifestyle a joyful experience. However, some mothers have trouble getting used to the new routines and re... |
Exploring nicotinamide cofactor promiscuity in NAD(P)H-dependent flavin containing monooxygenases (FMOs) using natural variation within the phosphate binding loop. Structure and activity of FMOs from <italic>Cellvibrio</italic> sp. BR and <italic>Pseudomonas stutzeri</italic> NF13 | Could not extract abstract | <contrib contrib-type="author" id="aut0005"><name><surname>Jensen</surname><given-names>Chantel N.</given-names></name><xref rid="aff0005" ref-type="aff">a</xref></contrib><contrib contrib-type="author" id="aut0010"><name><surname>Ali</surname><given-names>Sohail T.</given-names></name><xref rid="aff0010" ref-type="aff... | Journal of Molecular Catalysis. B, Enzymatic | <sec id="sec0005"><label>1</label><title>Introduction</title><p id="par0025">Flavin-containing monooxygenases (FMOs) <xref rid="bib0005" ref-type="bibr">[1]</xref> catalyse the oxygenation of heteroatoms, such as nitrogen and sulfur, in various organic substrates, and have been studied both for their role in metabolism... |
Divergent tissue and sex effects of rapamycin on the proteasome-chaperone network of old mice | <p>Rapamycin, an allosteric inhibitor of the mTOR kinase, increases longevity in mice in a sex-specific manner. In contrast to the widely accepted theory that a loss of proteasome activity is detrimental to both life- and healthspan, biochemical studies <italic>in vitro</italic> reveal that rapamycin inhibits 20S prote... | <contrib contrib-type="author"><name><surname>Rodriguez</surname><given-names>Karl A.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/172951"/></contrib><contrib contr... | Frontiers in Molecular Neuroscience | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>Rapamycin, an allosteric inhibitor of mechanistic (mammalian) target of rapamycin (mTOR) reportedly increases longevity in mice even when given at an advanced age as an encapsulated formulation in chow. This effect is significantly greater in females (M... |
Altered dynamics between neural systems sub-serving decisions for unhealthy food | <p>Using BOLD functional magnetic resonance imaging (fMRI) techniques, we examined the relationships between activities in the neural systems elicited by the decision stage of the Iowa Gambling Task (IGT), and food choices of either vegetables or snacks high in fat and sugar. Twenty-three healthy normal weight adolesce... | <contrib contrib-type="author"><name><surname>He</surname><given-names>Qinghua</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/184645"/></contrib><contrib contrib-type... | Frontiers in Neuroscience | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>With an increase of abundant and easily accessible high-calorie foods, an important characteristic of human choices in food is the unhealthy consumption of high calorie foods. Such choices can have long-term negative consequences, such as medical proble... |
From genes to behavior: placing cognitive models in the context of biological pathways | <p>Connecting neural mechanisms of behavior to their underlying molecular and genetic substrates has important scientific and clinical implications. However, despite rapid growth in our knowledge of the functions and computational properties of neural circuitry underlying behavior in a number of important domains, ther... | <contrib contrib-type="author"><name><surname>Saez</surname><given-names>Ignacio</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/6511"/></contrib><contrib contrib-type="author"><name><surname>Set</surname><given-names>... | Frontiers in Neuroscience | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>There is widespread interest in the application of formal computational models to connect behavior to its underlying biological substrates (Glimcher and Rustichini, <xref rid="B24" ref-type="bibr">2004</xref>; Sugrue et al., <xref rid="B67" ref-type="bi... |
Short-Term Adaptation of Joint Position Sense Occurs during and after Sustained Vibration of Antagonistic Muscle Pairs | <p>Proprioception is critical for the control of many goal-directed activities of daily living. While contributions from skin and joint receptors exist, the muscle spindle is thought to play an important role in allowing accurate judgments of limb position and movement to occur. The discharges elicited from muscle spin... | <contrib contrib-type="author"><name><surname>Gonzales</surname><given-names>Tomas I.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/172761"/></contrib><contrib contrib-type="a... | Frontiers in Human Neuroscience | <sec sec-type="introduction" id="S1"><title>Introduction</title><p>Sensory adaptation is a term that relates to the ability of a sensory system to change responsiveness over time. This process can be predictive in nature, as might be necessary for the case of sensory-motor learning. Alternatively, sensory adaptation ca... |
Neck Proprioception Shapes Body Orientation and Perception of Motion | <p>This review article deals with some effects of neck muscle proprioception on human balance, gait trajectory, subjective straight-ahead (SSA), and self-motion perception. These effects are easily observed during neck muscle vibration, a strong stimulus for the spindle primary afferent fibers. We first remind the earl... | <contrib contrib-type="author"><name><surname>Pettorossi</surname><given-names>Vito Enrico</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/191029"/></contrib><contrib contrib-type="author"><name><surname>Schieppati</surname><giv... | Frontiers in Human Neuroscience | <sec sec-type="intro" id="S1"><title>Introduction</title><p>To many aged professors of physiology (and young students as well), the term proprioception promptly calls to mind the tendon-tap reflex, i.e., the “monosynaptic” reflex elicited by a tap onto the patellar or Achilles’ tendon and the co... |
Mortality from external causes in Africa and Asia: evidence from INDEPTH Health and Demographic Surveillance System Sites | <sec id="st1"><title>Background</title><p>Mortality from external causes, of all kinds, is an important component of overall mortality on a global basis. However, these deaths, like others in Africa and Asia, are often not counted or documented on an individual basis. Overviews of the state of external cause mortality ... | <contrib contrib-type="author"><name><surname>Streatfield</surname><given-names>P. Kim</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Khan</surname><given-names>Wasi... | Global Health Action | <p>Mortality from external causes – whether unintentional (such as transport-related, falls, drowning, fires and burns, venoms, and poisons) or intentional (suicides and assaults) – forms a worldwide phenomenon of considerable magnitude. Which cause categories dominate in particular places and which age... |
Cause-specific childhood mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites | <sec id="st1"><title>
Background</title><p>Childhood mortality, particularly in the first 5 years of life, is a major global concern and the target of Millennium Development Goal 4. Although the majority of childhood deaths occur in Africa and Asia, these are also the regions where such deaths are least likely to be re... | <contrib contrib-type="author"><name><surname>Streatfield</surname><given-names>P. Kim</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Khan</surname><given-names>Wasi... | Global Health Action | <p>Mortality in childhood, particularly in the first 5 years of life, has been a major global concern in recent years. Additional attention has been given to rates of all-cause mortality reduction within the framework of Millennium Development Goal 4 (<xref rid="CIT0001" ref-type="bibr">1</xref>) and considerable succe... |
Cause-specific mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites | <sec id="st1"><title>Background</title><p>Because most deaths in Africa and Asia are not well documented, estimates of mortality are often made using scanty data. The INDEPTH Network works to alleviate this problem by collating detailed individual data from defined Health and Demographic Surveillance sites. By register... | <contrib contrib-type="author"><name><surname>Streatfield</surname><given-names>P. Kim</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Khan</surname><given-names>Wasi... | Global Health Action | <p>The vast majority of deaths in sub-Saharan Africa and southern Asia are not individually registered nor assigned a cause of death. Data from WHO (<xref rid="CIT0001" ref-type="bibr">1</xref>) show that, apart from in a few countries, the coverage of routine vital registration including cause of death in Africa and A... |
Who died of what in rural KwaZulu-Natal, South Africa: a cause of death analysis using InterVA-4 | <sec id="st1"><title>Background</title><p>For public health purposes, it is important to see whether men and women in different age groups die of the same causes in South Africa.</p></sec><sec id="st2"><title>Objective</title><p>We explored sex- and age-specific patterns of causes of deaths in a rural demographic surve... | <contrib contrib-type="author"><name><surname>Mossong</surname><given-names>Joël</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Byass</surname><given-names... | Global Health Action | <p>Despite the fact that the rationale for any successful health interventions should be informed by the cause of deaths (CODs) that are of the greatest importance locally, many developing countries lack this crucial information (<xref rid="CIT0001" ref-type="bibr">1</xref>). Verbal autopsy (VA) has been shown as a use... |
Adult non-communicable disease mortality in Africa and Asia: evidence from INDEPTH Health and Demographic Surveillance System sites | <sec id="st1"><title>Background</title><p>Mortality from non-communicable diseases (NCDs) is a major global issue, as other categories of mortality have diminished and life expectancy has increased. The World Health Organization's Member States have called for a 25% reduction in premature NCD mortality by 2025, which c... | <contrib contrib-type="author"><name><surname>Streatfield</surname><given-names>P. Kim</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Khan</surname><given-names>Wasi... | Global Health Action | <p>Mortality due to non-communicable diseases (NCDs) of various kinds has become an increasing focus of attention in recent years (<xref rid="CIT0001" ref-type="bibr">1</xref>), including at a special meeting of the UN General Assembly in September 2011 (<xref rid="CIT0002" ref-type="bibr">2</xref>). This has happened ... |
Cause-specific mortality and socioeconomic status in Chakaria, Bangladesh | <sec id="st1"><title>Background</title><p>Bangladesh has achieved remarkable gains in health indicators during the last four decades despite low levels of economic development. However, the persistence of inequities remains disturbing. This success was also accompanied by health and demographic transitions, which in tu... | <contrib contrib-type="author"><name><surname>Hanifi</surname><given-names>Syed M. A.</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Mahmood</surname><given-names>... | Global Health Action | <p>Bangladesh has recently been applauded as an ‘exceptional health performer’ for its achievements in health outcomes during the last four decades despite widespread poverty (<xref rid="CIT0001" ref-type="bibr">1</xref>–<xref rid="CIT0006" ref-type="bibr">6</xref>). Increased life expectancy at... |
Malaria mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance
system sites | <sec id="st1"><title>Background</title><p>Malaria continues to be a major cause of infectious disease mortality in tropical regions. However, deaths from malaria are most often not individually documented, and as a result overall understanding of malaria epidemiology is inadequate. INDEPTH Network members maintain popu... | <contrib contrib-type="author"><name><surname>Streatfield</surname><given-names>P. Kim</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Khan</surname><given-names>Wasi... | Global Health Action | <p>The epidemiology of malaria in Africa and Asia has been extensively, but not always systematically, investigated. Many studies have focused on young children’s exposure to the disease (<xref rid="CIT0001" ref-type="bibr">1</xref>), and to some extent the effects on pregnant women (<xref rid="CIT0002" ref-typ... |
HIV/AIDS-related mortality in Africa and Asia: evidence from INDEPTH health and demographic surveillance system sites | <sec id="st1"><title>Background</title><p>As the HIV/AIDS pandemic has evolved over recent decades, Africa has been the most affected region, even though a large proportion of HIV/AIDS deaths have not been documented at the individual level. Systematic application of verbal autopsy (VA) methods in defined populations p... | <contrib contrib-type="author"><name><surname>Streatfield</surname><given-names>P. Kim</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Khan</surname><given-names>Wasi... | Global Health Action | <p>The human immunodeficiency virus (HIV) and the consequent acquired immune deficiency syndrome (AIDS) caused a globally devastating pandemic starting in the late twentieth century. This pandemic caused mortality of such a magnitude as to distort population age–sex distributions in the worst affected areas (<x... |
Causes of death in two rural demographic surveillance sites in Bangladesh, 2004–2010: automated coding of verbal autopsies using InterVA-4 | <sec id="st1"><title>Objective</title><p>Population-based information on causes of death (CoD) by age, sex, and area is critical for countries with limited resources to identify and address key public health issues. This study analysed the demographic surveillance and verbal autopsy (VA) data to estimate age- and sex-s... | <contrib contrib-type="author"><name><surname>Alam</surname><given-names>Nurul</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Chowdhury</surname><given-names>Hafizur R.</given-names></name><xref ref-type="... | Global Health Action | <p>Reliable and up-to-date population-based statistics on morbidity and mortality by cause are important for health sector planning to combat ill health and ill-health-induced poverty. Such statistics, to our knowledge, are lacking in Bangladesh, except for children aged under 5 and maternal deaths for which data are a... |
Multisensory stimuli elicit altered oscillatory brain responses at gamma frequencies in patients with schizophrenia | <p>Deficits in auditory and visual unisensory responses are well documented in patients with schizophrenia; however, potential abnormalities elicited from multisensory audio-visual stimuli are less understood. Further, schizophrenia patients have shown abnormal patterns in task-related and task-independent oscillatory ... | <contrib contrib-type="author"><name><surname>Stone</surname><given-names>David B.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/66900"/></contrib><contrib contrib-type="author"><name><surname>Coffman</surname><given... | Frontiers in Human Neuroscience | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>On a moment-by-moment basis, behaviorally salient information reaches us from multiple senses and seamlessly shapes our perceptions and actions in the world. The capacity to organize the many stimuli arriving from different sensory modalities into a coh... |
Estimating cause of adult (15+ years) death using InterVA-4 in a rural district of southern Ghana | <sec id="st1"><title>Background</title><p>Data needed to estimate causes of death and the pattern of these deaths are scarce in sub-Saharan Africa. Such data are very important for targeting, monitoring, and evaluating health interventions.</p></sec><sec id="st2"><title>Objective</title><p>To estimate the mortality rat... | <contrib contrib-type="author"><name><surname>Awini</surname><given-names>Elizabeth</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name... | Global Health Action | <p>The ability to have a healthy long life is an essential part of development. Survival can, thus, be said to be a measure of a country's development (<xref rid="CIT0001" ref-type="bibr">1</xref>). For interventions to be effectively implemented and tailored to the right people, it is important for policy makers and p... |
Comparing causes of death between formal and informal neighborhoods in urban Africa: evidence from Ouagadougou Health and Demographic Surveillance System | <sec id="st1"><title>Background</title><p>The probable coexistence of two or more epidemiological profiles in urban Africa is poorly documented. In particular, very few studies have focused on the comparison of cause-specific mortality between two types of neighborhoods that characterize contemporary southern cities: f... | <contrib contrib-type="author"><name><surname>Soura</surname><given-names>Abdramane Bassiahi</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Lankoande</surname><given-names>Bruno</given-names></name><xref r... | Global Health Action | <p>Demographic transition, defined as the decline in mortality and fertility resulting from socio-economic development, is usually followed by epidemiological transition. The latter is the evolution in which infectious and parasitic diseases, as leading causes of morbidity and death, are gradually replaced by chronic c... |
Applying the InterVA-4 model to determine causes of death in rural Ethiopia | <sec id="st1"><title>Background</title><p>In Ethiopia, most deaths take place at home and routine certification of cause of death by physicians is lacking. As a result, reliable cause of death (CoD) data are often not available. Recently, a computerized method for interpretation of verbal autopsy (VA) data, called Inte... | <contrib contrib-type="author"><name><surname>Weldearegawi</surname><given-names>Berhe</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Melaku</surname><given-names>... | Global Health Action | <p>Information about causes of death (CoD) is needed by health managers and policy makers at all levels of governance (<xref rid="CIT0001" ref-type="bibr">1</xref>, <xref rid="CIT0002" ref-type="bibr">2</xref>). In countries where registration of vital events and medical documentation of death are practiced, such infor... |
Microbial contributions to coupled arsenic and sulfur cycling in the acid-sulfide hot spring Champagne Pool, New Zealand | <p>Acid-sulfide hot springs are analogs of early Earth geothermal systems where microbial metal(loid) resistance likely first evolved. Arsenic is a metalloid enriched in the acid-sulfide hot spring Champagne Pool (Waiotapu, New Zealand). Arsenic speciation in Champagne Pool follows reaction paths not yet fully understo... | <contrib contrib-type="author"><name><surname>Hug</surname><given-names>Katrin</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="author-notes" rid="fn001"><sup>*</sup></xref><uri xlink:type="simple" xlink:href="http://community.frontiersin.org/people/u/164375"/></contrib><contrib co... | Frontiers in Microbiology | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>Active geothermal springs provide a modern analog for environments in which early life on Earth evolved metal(loid) resistance mechanisms (Stetter, <xref rid="B57" ref-type="bibr">2006</xref>; Martin et al., <xref rid="B37" ref-type="bibr">2008</xref>).... |
Cause-specific mortality at INDEPTH Health and Demographic Surveillance System Sites in Africa and Asia: concluding synthesis | <p>This synthesis brings together findings on cause-specific mortality documented by means of verbal autopsies applied to over 110,000 deaths across Africa and Asia, within INDEPTH Network sites.</p><sec id="st1"><title>Methods</title><p>Developments in computerised methods to assign causes of death on the basis of dat... | <contrib contrib-type="author"><name><surname>Sankoh</surname><given-names>Osman</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><s... | Global Health Action | <p>This Special Issue on cause-specific mortality has described an unprecedented dataset – more than 110,000 deaths in African and Asian sites, documented over 12 million person-years of population-based surveillance (<xref rid="CIT0001" ref-type="bibr">1</xref>). By way of synthesis across the detailed papers,... |