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Pregnancy-related mortality in Africa and Asia: evidence from INDEPTH Health and Demographic Surveillance System sites | <sec id="st1"><title>Background</title><p>Women continue to die in unacceptably large numbers around the world as a result of pregnancy, particularly in sub-Saharan Africa and Asia. Part of the problem is a lack of accurate, population-based information characterising the issues and informing solutions. Population surv... | <contrib contrib-type="author"><name><surname>Streatfield</surname><given-names>P. Kim</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref></contrib><contrib contrib-type="author"><name><surname>Alam</surname><given-names>Nuru... | Global Health Action | <p>The tragedy of women dying in the context of being pregnant or giving birth continues to be a major, but almost entirely avoidable, problem. A number of countries consistently achieve a maternal mortality ratio (MMR) of less than 10 maternal deaths per 100,000 live births, but the global MMR remains at levels of sev... |
Causes of death among persons of all ages within the Kilifi Health and Demographic Surveillance System, Kenya, determined from verbal autopsies interpreted using the InterVA-4 model | <sec id="st1"><title>Background</title><p>The vast majority of deaths in the Kilifi study area are not recorded through official systems of vital registration. As a result, few data are available regarding causes of death in this population.</p></sec><sec id="st2"><title>Objective</title><p>To describe the causes of de... | <contrib contrib-type="author"><name><surname>Ndila</surname><given-names>Carolyne</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Bauni</surname><given-names>Evasi... | Global Health Action | <p>In developed countries, cause-specific mortality data are readily available from well-established vital registration systems. In developing countries, however, where a majority of the world’s deaths occur, vital registration systems are poor (<xref rid="CIT0001" ref-type="bibr">1</xref>), access to health ca... |
Distribution of cause of death in rural Bangladesh during 2003–2010: evidence from two rural areas within Matlab Health and Demographic Surveillance site | <sec id="st1"><title>Objective</title><p>This study used the InterVA-4 computerised model to assign probable cause of death (CoD) to verbal autopsies (VAs) generated from two rural areas, with a difference in health service provision, within the Matlab Health and Demographic Surveillance site (HDSS). This study aimed t... | <contrib contrib-type="author"><name><surname>Alam</surname><given-names>Nurul</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Chowdhury</surname><given-names>Hafizur R.</given-names></name><xref ref-type="... | Global Health Action | <p>Bangladesh is the most densely populated and the eighth most populous country in the world (<xref rid="CIT0001" ref-type="bibr">1</xref>). Despite its widespread poverty, turbulent past, and occasionally extreme climate events, the country has made remarkable progress in the last four decades in providing vaccines t... |
Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes on <italic>in vitro</italic> Stimulated T Cells | <p>In the recent years, it has been demonstrated that the biological activity of mesenchymal stem cells (MSCs) is mediated through the release of paracrine factors. Many of these factors are released into exosomes, which are small membranous vesicles that participate in cell–cell communication. Exosomes from MS... | <contrib contrib-type="author"><name><surname>Blazquez</surname><given-names>Rebeca</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><uri xlink:type="simple" xlink:href="http://frontiersin.org/people/u/191128"/></contrib><contrib contrib-type="author"><name><surname>Sanchez-Margallo</surname><give... | Frontiers in Immunology | <sec sec-type="introduction" id="S1"><title>Introduction</title><p>Exosomes are small membranous vesicles secreted by most cell types. These vesicles participate in cell–cell communication and their content consists of RNA, lipids, and proteins. Some of these proteins (i.e., CD9, CD63, or CD81) are ubiquitously... |
Moving towards better cause of death registration in Africa and Asia | Could not extract abstract | <contrib contrib-type="author"><name><surname>Boerma</surname><given-names>Ties</given-names></name><role>Director</role></contrib> | Global Health Action | <p>Mortality statistics by age, sex, and cause of death are the foundations of public health programmes. They are essential for planning, programming, and monitoring progress. Ideally, mortality statistics should be available for small areas, to detect differences in the distribution of mortality risks and plan health ... |
Two decades of mortality change in rural northeast South Africa | <sec id="st1"><title>Background</title><p>The MRC/Wits University Agincourt research centre, part of the INDEPTH Network, has documented mortality in a defined population in the rural northeast of South Africa for 20 years (1992–2011) using long-term health and socio-demographic surveillance. Detail on the unfo... | <contrib contrib-type="author"><name><surname>Kabudula</surname><given-names>Chodziwadziwa W.</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Tollman</surname><give... | Global Health Action | <p>The Agincourt Health and Socio-Demographic Surveillance System (HDSS) of the MRC/Wits Rural Public Health and Health Transitions Research Unit is an INDEPTH member site situated in the northeast of South Africa. The HDSS has been documenting mortality in a rural population since 1992. As of 2011, the population comp... |
Trends in non-communicable disease mortality among adult residents in Nairobi's slums, 2003–2011: applying InterVA-4 to verbal autopsy data | <sec id="st1"><title>Background</title><p>About 80% of deaths from non-communicable diseases (NCDs) occur in developing countries such as Kenya. However, not much is known about the burden of NCDs in slums, which account for about 60% of the residences of the urban population in Kenya. This study examines trends in NCD... | <contrib contrib-type="author"><name><surname>Oti</surname><given-names>Samuel O.</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="aff" rid="AF0003">3</xref><xref ref-type="aff" rid="AF0004">4</xref><xref ref-type="corresp" rid="cor1">*</xref></cont... | Global Health Action | <p>Non-communicable diseases (NCDs) are traditionally considered to be diseases of affluent societies. However, global projections show that the largest increase in deaths from NCDs will occur in low-resource settings where, already, 80% of global NCD deaths occur (<xref rid="CIT0001" ref-type="bibr">1</xref>, <xref ri... |
Taspase1 cleaves MLL1 to activate cyclin E for HER2/neu breast tumorigenesis | <p>Taspase1, a highly conserved threonine protease, cleaves nuclear transcriptional regulators mixed-lineage leukemia (MLL, MLL1), MLL2, TFIIA, and ALF to orchestrate a wide variety of biological processes. <italic>In vitro</italic> studies thus far demonstrated that Taspase1 plays important roles in the proliferation ... | <contrib contrib-type="author"><name><surname>Dong</surname><given-names>Yiyu</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="author-notes" rid="note1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><name><surname>Van Tine</surname><given-names>Brian A</given-names></nam... | Cell Research | <sec sec-type="intro"><title>Introduction</title><p>Human breast cancer is a heterogeneous disease comprised of three major subgroups, each encompassing unique molecular signatures, prognoses, and responses to therapies<sup><xref ref-type="bibr" rid="bib1">1</xref></sup>. HER2 is a member of the epidermal growth factor... |
Postzygotic single-nucleotide mosaicisms in whole-genome sequences of clinically unremarkable individuals | <p>Postzygotic single-nucleotide mutations (pSNMs) have been studied in cancer and a few other overgrowth human disorders at whole-genome scale and found to play critical roles. However, in clinically unremarkable individuals, pSNMs have never been identified at whole-genome scale largely due to technical difficulties ... | <contrib contrib-type="author"><name><surname>Huang</surname><given-names>August Y</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="author-notes" rid="note1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><name><surname>Xu</surname>... | Cell Research | <sec sec-type="intro"><title>Introduction</title><p>Genomic mosaicism is a biological phenomenon in which genetic alterations occurring during development or aging give rise to two or more cell populations with distinct genome sequences within one individual<sup><xref ref-type="bibr" rid="bib1">1</xref>,<xref ref-type=... |
<italic>De novo</italic> mutation in <italic>ATP6V1B2</italic> impairs lysosome acidification and causes dominant deafness-onychodystrophy syndrome | Could not extract abstract | <contrib contrib-type="author"><name><surname>Yuan</surname><given-names>Yongyi</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="author-notes" rid="note1"><sup>*</sup></xref></contrib><contrib contrib-type="author"><name><surname>Zhang</surname>... | Cell Research | <sec><title>Dear Editor,</title><p>Dominant deafness-onychodystrophy syndrome (DDOD syndrome; MIM 124480) is characterized mainly by congenital sensorineural hearing loss accompanied by dystrophic or absent nails. Prominent differences between DDOD syndrome and DOORS syndrome (deafness, onychodystrophy, osteodystrophy,... |
Disease-specific mortality burdens in a rural Gambian population using verbal autopsy, 1998–2007 | <sec id="st1"><title>Objective</title><p>To estimate and evaluate the cause-of-death structure and disease-specific mortality rates in a rural area of The Gambia as determined using the InterVA-4 model.</p></sec><sec id="st2"><title>Design</title><p>Deaths and person-years of observation were determined by age group fo... | <contrib contrib-type="author"><name><surname>Jasseh</surname><given-names>Momodou</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Howie</surname><given-names>Steph... | Global Health Action | <p>The development of a successful health care system should be supported by information on the frequency of specific diseases and their contribution to morbidity and mortality in the population. Therefore, measuring mortality, including cause-of-death determination, enhances every level of health care planning, resour... |
Controlling for population structure and genotyping platform bias in the eMERGE multi-institutional biobank linked to electronic health records | <p>Combining samples across multiple cohorts in large-scale scientific research programs is often required to achieve the necessary power for genome-wide association studies. Controlling for genomic ancestry through principal component analysis (PCA) to address the effect of population stratification is a common practi... | <contrib contrib-type="author"><name><surname>Crosslin</surname><given-names>David R.</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="author-notes" rid="fn001"><sup>*</sup></xref><xref ref-type="author-notes" rid="fn003"><sup>�... | Frontiers in Genetics | <sec id="s1"><title>1. Introduction</title><p>To reach the statistical power needed for genome-wide association studies, large numbers of participants are needed. This can be achieved through large research networks such as the Electronic Medical Records and Genomics (eMERGE) Network, which comprises a multi-ethnic coh... |
Cause of death during 2009–2012, using a probabilistic model (InterVA-4): an experience from Ballabgarh Health and Demographic Surveillance System in India | <sec id="st1"><title>Objectives</title><p>The present study aimed to estimate the age and cause-specific mortality in Ballabgarh Health and Demographic Surveillance System (HDSS) site for the years 2009 to 2012, using a probabilistic model (InterVA-4).</p></sec><sec id="st2"><title>Methods</title><p>All Deaths in Balla... | <contrib contrib-type="author"><name><surname>Rai</surname><given-names>Sanjay K.</given-names></name><xref ref-type="aff" rid="AF0001">1</xref><xref ref-type="aff" rid="AF0002">2</xref></contrib><contrib contrib-type="author"><name><surname>Kant</surname><given-names>Shashi</given-names></name><xref ref-type="aff" rid... | Global Health Action | <p>Death recording by age, sex, and cause, and calculating mortality rates and differentials are central to evidence-based health policy, monitoring, and evaluation (<xref rid="CIT0001" ref-type="bibr">1</xref>). Mortality levels are significant indicators of population health, and are of extreme importance to prioriti... |
Multi-omic landscape of rheumatoid arthritis: re-evaluation of drug adverse effects | <p><bold>Objective:</bold> To provide a frame to estimate the systemic impact (side/adverse events) of (novel) therapeutic targets by taking into consideration drugs potential on the numerous districts involved in rheumatoid arthritis (RA) from the inflammatory and immune response to the gut-intestinal (GI) microbiome.... | <contrib contrib-type="author"><name><surname>Tieri</surname><given-names>Paolo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="author-notes" rid="fn001"><sup>*</sup></xref><xref ref-type="author-notes" rid="fn004"><sup>†<... | Frontiers in Cell and Developmental Biology | <sec sec-type="introduction" id="s1"><title>Introduction</title><p>Rheumatoid arthritis (RA) is a multifaceted autoimmune, chronic and inflammatory disease with, to date, unclear etiology. As a consequence of its complexity, the definition of efficient and effective therapies remains a remarkable challenge due to the d... |
T lymphocytes are not required for the development of fatty degeneration after rotator cuff tear | <sec><title>Objectives </title><p>Rotator cuff tears are among the most common and debilitating
upper extremity injuries. Chronic cuff tears result in atrophy and
an infiltration of fat into the muscle, a condition commonly referred
to as ‘fatty degeneration’. While stem cell therapies hold promise
for ... | <contrib id="c1" contrib-type="author"><name><surname>Gumucio</surname><given-names>J.</given-names></name><degrees>BS</degrees><role>PhD
Student</role><xref ref-type="aff" rid="a1">1</xref></contrib><contrib id="c2" contrib-type="author"><name><surname>Flood</surname><given-names>M.</given-names></name><degrees>BS</de... | Bone & Joint Research | <sec><title>Article focus </title><list list-type="bullet"><list-item><p>To assess the role of T lymphocytes in the development of fatty
degeneration following rotator cuff tear</p></list-item><list-item><p>To evaluate the viability of an immunodeficient rodent model
that could be used to study xenograft-based therapie... |
Validation of a model-based measurement
of the minimum insert thickness of knee prostheses | <sec><title>Introduction</title><p>Wear of polyethylene inserts plays an important role in failure
of total knee replacement and can be monitored <italic>in vivo</italic> by
measuring the minimum joint space width in anteroposterior radiographs.
The objective of this retrospective cross-sectional study was to
compare t... | <contrib id="c1" contrib-type="author"><name><surname>van IJsseldijk</surname><given-names>E. A.</given-names></name><degrees>MSc</degrees><role>PhD student</role><xref ref-type="aff" rid="a1">1</xref><uri content-type="homepage" xlink:type="simple" xlink:href="http://orthodox.boneandjoint.org.uk/viewprofileinfo.aspx?a... | Bone & Joint Research | <sec><title>Article Focus</title><p>Comparing the accuracy and precision of two minimum joint space
width measurement methods for assessing insert wear in total knee
prostheses</p><p>Investigating the relationship between locations of the minimum
joint space width measurement and minimum insert thickness</p></sec><sec>... |
Patients’ perspectives on providing a stool sample to their GP: a qualitative study | <sec><title>Background</title><p>Stool specimen collection is challenging and informal feedback has indicated that participants find the process difficult. Increasing stool specimen returns would improve the investigation of outbreaks of diarrhoeal and food-borne disease.</p></sec><sec><title>Aim</title><p>To explore t... | <contrib contrib-type="author"><name><surname>Lecky</surname><given-names>Donna M</given-names></name><degrees>PhD</degrees><role>Project manager</role></contrib><aff>Public Health England Primary Care Unit, Gloucester.</aff> | The British Journal of General Practice | <sec sec-type="intro"><title>INTRODUCTION</title><p>Collecting a stool specimen can be a definitive step in determining the diagnosis and appropriate treatment for suspected infectious diarrhoea and other gastrointestinal disease.<xref rid="b1" ref-type="bibr">1</xref> Stool culture results also form the basis of ongoi... |
Ethnicity and the diagnosis gap in liver disease: a population-based study | <sec><title>Background</title><p>Liver disease is a major cause of morbidity and mortality worldwide. Large numbers of liver function tests (LFTs) are performed in primary care, with abnormal liver biochemistry a common finding. Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver injury.... | <contrib contrib-type="author"><name><surname>Alazawi</surname><given-names>William</given-names></name><degrees>MA, PhD, MRCP</degrees><role>Senior lecturer and consultant in hepatology</role></contrib><aff>The Liver Unit, The Blizard Institute, Barts & The London School of Medicine, London, UK.</aff> | The British Journal of General Practice | <sec sec-type="intro"><title>INTRODUCTION</title><p>Hospital admissions and deaths from liver disease are rising across the Western world.<xref rid="b1" ref-type="bibr">1</xref>,<xref rid="b2" ref-type="bibr">2</xref> Most epidemiological studies focus on prevalence rates of individual diseases in selected hospital pop... |
Recent Research on Febrile Seizures: A Review | <p id="P1">Febrile seizures are common and mostly benign. They are the most common cause of seizures in children less than five years of age. There are two categories of febrile seizures, simple and complex. Both the International League against Epilepsy and the National Institute of Health has published definitions on... | <contrib contrib-type="author"><name><surname>Syndi Seinfeld</surname><given-names>DO</given-names></name><xref rid="FN1" ref-type="author-notes">*</xref></contrib><contrib contrib-type="author"><name><surname>Pellock</surname><given-names>John M.</given-names></name></contrib><aff id="A1">Department of Neurology, Virg... | Journal of neurology & neurophysiology | <sec sec-type="intro" id="S1"><title>Introduction</title><p id="P2">Febrile seizures (FS) are the single most common seizure type and occur in 2 to 5% of children younger than age 5 years with a peak incidence in the second year of life [<xref rid="R1" ref-type="bibr">1</xref>]. Historically FS were studied using large... |
A Perspective on the Potential of Human iPS Cell-Based Therapies for Muscular Dystrophies: Advancements so far and Hurdles to Overcome | Could not extract abstract | <contrib contrib-type="author"><name><surname>Darabi</surname><given-names>Radbod</given-names></name></contrib><contrib contrib-type="author"><name><surname>Perlingeiro</surname><given-names>Rita C.R.</given-names></name><xref rid="FN1" ref-type="author-notes">*</xref></contrib><aff id="A1">Lillehei Heart Institute, D... | Journal of stem cell research & therapy | <p id="P1">Pluripotent stem cells [<xref rid="R1" ref-type="bibr">1</xref>,<xref rid="R2" ref-type="bibr">2</xref>] are well-known for their unique self-renewal and differentiation capabilities, which make these cells very favorable for cell-based therapeutic applications in degenerative disorders such as muscular dyst... |
Thermally assisted electric field control of magnetism in flexible multiferroic heterostructures | <p>Thermal and electrical control of magnetic anisotropy were investigated in flexible Fe<sub>81</sub>Ga<sub>19</sub> (FeGa)/Polyvinylidene fluoride (PVDF) multiferroic heterostructures. Due to the large anisotropic thermal deformation of PVDF (<italic>α</italic><sub>1</sub> = −13 × 10<sup>... | <contrib contrib-type="author"><name><surname>Liu</surname><given-names>Yiwei</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Zhan</surname><given-names>Qingfeng</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff" rid="a1">... | Scientific Reports | <p>The possibility of controlling magnetism with an electric field, which can be realized by using a kind of multiferroic materials showing coupled ferroelectricity and ferromagnetism, opens a new way for appealing novel magnetization control schemes in future low power consumed spintronic devices<xref ref-type="bibr" ... |
Symmetrically periodic segregation in a vertically vibrated binary granular bed | <p>Periodic segregation behaviors in fine mixtures of copper and alumina particles, including both percolation and eruption stages, are experimentally investigated by varying the ambient air pressure and vibrational acceleration. For the cases with moderate air pressure, the heaping profile of the granular bed keeps sy... | <contrib contrib-type="author"><name><surname>Wen</surname><given-names>Pingping</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Zheng</surname><given-names>Ning</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff" rid="a1">... | Scientific Reports | <p>Granular segregation induced by external excitation is of importance in industrial and scientific society, widely applied in the agriculture, food and pharmaceutical processing, and ore dressing<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref><xref ref-type="bibr" rid="b3">3</xref><xref ... |
Re-building Daniell Cell with a Li-ion exchange Film | <p>Daniell cell (i.e. Zn-Cu battery) is widely used in chemistry curricula to illustrate how batteries work, although it has been supplanted in the late 19th century by more modern battery designs because of Cu<sup>2+</sup>-crossover-induced self-discharge and un-rechargeable characteristic. Herein, it is re-built by u... | <contrib contrib-type="author"><name><surname>Dong</surname><given-names>Xiaoli</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Wang</surname><given-names>Yonggang</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff" rid="a1... | Scientific Reports | <p>Daniell cell, invented by the British chemist John Frederic Daniell in 1836, is popularly known as a kind of zinc-copper battery which takes advantage of a porous barrier between the two metals<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref>. Once used widely in the European telegraph i... |
Preen secretions encode information on MHC similarity in certain sex-dyads in a monogamous seabird | <p>Animals are known to select mates to maximize the genetic diversity of their offspring in order to achieve immunity against a broader range of pathogens. Although several bird species preferentially mate with partners that are dissimilar at the major histocompatibility complex (MHC), it remains unknown whether they ... | <contrib contrib-type="author"><name><surname>Leclaire</surname><given-names>Sarah</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff" rid="a1">1</xref><xref ref-type="aff" rid="a2">2</xref><xref ref-type="author-notes" rid="n1">*</xref></contrib><contrib contrib-type="author"><name><surn... | Scientific Reports | <p>The major histocompatibility complex (MHC) is an extraordinarily diverse cluster of genes that play a major role in vertebrate adaptive immunity. MHC heterozygosity offers several fitness advantages, including increased disease resistance and survival<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="... |
GWATCH: a web platform for automated gene association discovery analysis | <sec><title>Background</title><p>As genome-wide sequence analyses for complex human disease determinants are expanding, it is increasingly necessary to develop strategies to promote discovery and validation of potential disease-gene associations.</p></sec><sec><title>Findings</title><p>Here we present a dynamic web-bas... | <contrib contrib-type="author" corresp="yes" equal-contrib="yes" id="A1"><name><surname>Svitin</surname><given-names>Anton</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>anton.svitin@gmail.com</email></contrib><contrib contrib-type="author" equal-contrib="yes" id="A2"><name><surname>Malov</surname><gi... | GigaScience | <sec><title>Findings</title><sec><title>Introduction</title><p>Annotations of human genome variation have identified some 60 million single nucleotide polymorphisms (SNPs), which offer the promise of connecting nucleotide and structural variation to hereditary traits [<xref ref-type="bibr" rid="B1">1</xref>-<xref ref-t... |
Epidemiology of in-hospital trauma deaths in a Brazilian university hospital | <sec><title>Background</title><p>The analysis of patterns of trauma deaths may improve the evaluation of a trauma system and identify areas that may benefit from more resources. The objective of this study was to analyze the epidemiology of trauma deaths in a Brazilian university hospital in order to assess the profile... | <contrib contrib-type="author" corresp="yes" id="A1"><name><surname>Trajano</surname><given-names>Adriano D</given-names></name><xref ref-type="aff" rid="I1">1</xref><email>adrianotrajano@gmail.com</email></contrib><contrib contrib-type="author" id="A2"><name><surname>Pereira</surname><given-names>Bruno M</given-names>... | BMC Emergency Medicine | <sec><title>Background</title><p>Globally, external causes of death are a major challenge to public health authorities
[<xref ref-type="bibr" rid="B1">1</xref>]. They account for more than five million deaths annually worldwide and cause temporary or permanent disability to millions more, representing about 9% of globa... |
Frequency-Controls of Electromagnetic Multi-Beam Scanning by Metasurfaces | <p>We propose a method to control electromagnetic (EM) radiations by holographic metasurfaces, including to producing multi-beam scanning in one dimension (1D) and two dimensions (2D) with the change of frequency. The metasurfaces are composed of subwavelength metallic patches on grounded dielectric substrate. We prese... | <contrib contrib-type="author"><name><surname>Li</surname><given-names>Yun Bo</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Wan</surname><given-names>Xiang</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="autho... | Scientific Reports | <p>In recent years, it has been shown that extreme controls of electromagnetic (EM) waves can be achieved by using metasurfaces. Due to advantages of smaller physical space and less lossy structures than bulk metamaterial<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref><xref ref-type="bibr"... |
Level Anticrossing of Impurity States in Semiconductor Nanocrystals | <p>The size dependence of the quantized energies of elementary excitations is an essential feature of quantum nanostructures, underlying most of their applications in science and technology. Here we report on a fundamental property of impurity states in semiconductor nanocrystals that appears to have been overlooked&#x... | <contrib contrib-type="author"><name><surname>Baimuratov</surname><given-names>Anvar S.</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff" rid="a1">1</xref><xref ref-type="aff" rid="a2">2</xref></contrib><contrib contrib-type="author"><name><surname>Rukhlenko</surname><given-names>Ivan D... | Scientific Reports | <p>Colloidal semiconductor nanocrystals, also known as quantum dots, have unique optical and electronic properties that are controlled by their size, shape and chemical composition<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref><xref ref-type="bibr" rid="b3">3</xref><xref ref-type="bibr" r... |
Genetic markers for toxicity of adjuvant oxaliplatin and fluoropyrimidines in the phase III TOSCA trial in high-risk colon cancer patients | <p>We investigated 17 polymorphisms in 11 genes (<italic>TS, MTHFR, ERCC1, XRCC1, XRCC3, XPD, GSTT1, GSTP1, GSTM1, ABCC1, ABCC2</italic>) for their association with the toxicity of fluoropyrimidines and oxaliplatin in colorectal cancer patients enrolled in a prospective randomized trial of adjuvant chemotherapy. The TO... | <contrib contrib-type="author"><name><surname>Ruzzo</surname><given-names>Annamaria</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff" rid="a1">1</xref><xref ref-type="author-notes" rid="n1">*</xref></contrib><contrib contrib-type="author"><name><surname>Graziano</surname><given-names>Fr... | Scientific Reports | <p>Adjuvant chemotherapy is the standard of care for stage III colorectal cancer patients and an accepted treatment option for high-risk stage II patients<xref ref-type="bibr" rid="b1">1</xref>. Standard regimens include oxaliplatin combined with bolus/infusional 5-fluorouracil (FOLFOX) or capecitabine (XELOX)<xref ref... |
Efficient bi-allelic gene knockout and site-specific knock-in mediated by TALENs in pigs | <p>Pigs are ideal organ donors for xenotransplantation and an excellent model for studying human diseases, such as neurodegenerative disease. Transcription activator-like effector nucleases (TALENs) are used widely for gene targeting in various model animals. Here, we developed a strategy using TALENs to target the <it... | <contrib contrib-type="author"><name><surname>Yao</surname><given-names>Jing</given-names></name><xref ref-type="aff" rid="a1">1</xref><xref ref-type="aff" rid="a2">2</xref></contrib><contrib contrib-type="author"><name><surname>Huang</surname><given-names>Jiaojiao</given-names></name><xref ref-type="aff" rid="a1">1</x... | Scientific Reports | <p>Pigs have been extensively used in biomedical research and are an excellent models for human diseases, especially for cardiovascular disease, atherosclerosis, cutaneous pharmacology, wound repair, cancer, diabetes, ophthalmological studies, toxicology research, lipoprotein metabolism, lung disease, and neurodegenera... |
Anatomy and efficiency of urban multimodal mobility | <p>The growth of transportation networks and their increasing interconnections, although positive, has the downside effect of an increasing complexity which make them difficult to use, to assess, and limits their efficiency. On average in the UK, 23% of travel time is lost in connections for trips with more than one mo... | <contrib contrib-type="author"><name><surname>Gallotti</surname><given-names>Riccardo</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Barthelemy</surname><given-names>Marc</given-names></name><xref ref-type="corresp" rid="c1">a</xref><xref ref-type="aff"... | Scientific Reports | <p>Although the coupling between different transportation networks is fundamental<xref ref-type="bibr" rid="b1">1</xref>, most of the studies on Public Transport Networks have been performed considering only one single transportation mode: private cars<xref ref-type="bibr" rid="b2">2</xref><xref ref-type="bibr" rid="b3... |
Incident light adjustable solar cell by periodic nanolens architecture | <p>Could nanostructures act as lenses to focus incident light for efficient utilization of photovoltaics? Is it possible, in order to avoid serious recombination loss, to realize periodic nanostructures in solar cells without direct etching in a light absorbing semiconductor? Here we propose and demonstrate a promising... | <contrib contrib-type="author"><name><surname>Yun</surname><given-names>Ju-Hyung</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Lee</surname><given-names>Eunsongyi</given-names></name><xref ref-type="aff" rid="a2">2</xref></contrib><contrib contrib-type... | Scientific Reports | <p>Many approaches have been reported to achieve low-cost<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref><xref ref-type="bibr" rid="b3">3</xref><xref ref-type="bibr" rid="b4">4</xref><xref ref-type="bibr" rid="b5">5</xref><xref ref-type="bibr" rid="b6">6</xref><xref ref-type="bibr" rid="b7... |
The effect of fluorescent nanodiamonds on neuronal survival and morphogenesis | <p>Nanodiamond (ND) has emerged as a promising carbon nanomaterial for therapeutic applications. In previous studies, ND has been reported to have outstanding biocompatibility and high uptake rate in various cell types. ND containing nitrogen-vacancy centers exhibit fluorescence property is called fluorescent nanodiamo... | <contrib contrib-type="author"><name><surname>Huang</surname><given-names>Yung-An</given-names></name><xref ref-type="aff" rid="a1">1</xref><xref ref-type="aff" rid="a2">2</xref><xref ref-type="author-notes" rid="n1">*</xref></contrib><contrib contrib-type="author"><name><surname>Kao</surname><given-names>Chun-Wei</giv... | Scientific Reports | <p>Nanodiamond (ND), a carbon derivative nanomaterial has become a promising candidate for biomedical applications<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref><xref ref-type="bibr" rid="b3">3</xref><xref ref-type="bibr" rid="b4">4</xref><xref ref-type="bibr" rid="b5">5</xref><xref ref-t... |
Controllable Schottky Barriers between MoS<sub>2</sub> and Permalloy | <p>MoS<sub>2</sub> is a layered two-dimensional material with strong spin-orbit coupling and long spin lifetime, which is promising for electronic and spintronic applications. However, because of its large band gap and small electron affinity, a considerable Schottky barrier exists between MoS<sub>2</sub> and contact m... | <contrib contrib-type="author"><name><surname>Wang</surname><given-names>Weiyi</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Liu</surname><given-names>Yanwen</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="aut... | Scientific Reports | <p>Molybdenum disulphide (MoS<sub>2</sub>) is a layered two-dimensional (2D) material, which draws intensive attention because of its unique electrical, optical and mechanical properties. It has been considered as a promising candidate for various future nanoelectronic and spintronic applications. It is a semiconductor... |
Continuity of states between the cholesteric → line hexatic transition and the condensation transition in DNA solutions | <p>A new method of finely temperature-tuning osmotic pressure allows one to identify the cholesteric → line hexatic transition of oriented or unoriented long-fragment DNA bundles in monovalent salt solutions as first order, with a small but finite volume discontinuity. This transition is similar to the osmotic ... | <contrib contrib-type="author"><name><surname>Yasar</surname><given-names>Selcuk</given-names></name><xref ref-type="aff" rid="a1">1</xref></contrib><contrib contrib-type="author"><name><surname>Podgornik</surname><given-names>Rudolf</given-names></name><xref ref-type="aff" rid="a1">1</xref><xref ref-type="aff" rid="a2... | Scientific Reports | <p>DNA at elevated osmotic pressures, accessible in highly concentrated DNA solutions <italic>in vitro</italic>, exhibits a sequence of ordered liquid-crystalline mesophases<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref><xref ref-type="bibr" rid="b3">3</xref> whose properties determine th... |
Retracted: Why Fish Oil Fails: A Comprehensive 21st Century Lipids-Based Physiologic Analysis | Could not extract abstract | <contrib contrib-type="author"><name><surname>Journal of Lipids</surname><given-names/></name><xref ref-type="corresp" rid="cor1">*</xref></contrib> | Journal of Lipids | <p>The article titled “<italic>Why Fish Oil Fails: A Comprehensive 21st Century Lipids-Based Physiologic Analysis</italic>” [<xref rid="B1" ref-type="bibr">1</xref>], published in Journal of Lipids has been retracted as a result of an undeclared competing interest on the part of the manuscript's author.... |
Effects of cobalt-chromium everolimus eluting stents or bare metal stent on fatal and non-fatal cardiovascular events: patient level meta-analysis | <p><bold>Objectives</bold> To examine the safety and effectiveness of cobalt-chromium everolimus eluting stents compared with bare metal stents.</p><p><bold>Design</bold> Individual patient data meta-analysis of randomised controlled trials. Cox proportional regression models stratified by trial, containing random effe... | <contrib contrib-type="author" corresp="yes"><name><surname>Valgimigli</surname><given-names>Marco</given-names></name><role>associate professor of medicine</role><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Sabaté</surname><given-names>Manel</given-names></nam... | The BMJ | <sec sec-type="intro"><title>Introduction</title><p>Randomised controlled trials,<xref rid="ref1" ref-type="bibr">1</xref>
<xref rid="ref2" ref-type="bibr">2</xref> a meta-analysis,<xref rid="ref3" ref-type="bibr">3</xref> and an observational study<xref rid="ref4" ref-type="bibr">4</xref> have consistently shown reduc... |
Maximizing Social Model Principles in Residential Recovery Settings | <title>Abstract</title><p>Peer support is integral to a variety of approaches to alcohol and drug problems. However, there is limited information about the best ways to facilitate it. The “social model” approach developed in California offers useful suggestions for facilitating peer support in residenti... | <contrib contrib-type="author"><name><surname>Polcin</surname><given-names>Douglas</given-names></name><degrees>Ed.D.</degrees><xref ref-type="aff" rid="AFF0001">
<sup>a</sup>
</xref><xref ref-type="corresp" rid="AN0001">
<sup>*</sup>
</xref></contrib><contrib contrib-type="author"><name><surname>Mericle</surname><give... | Journal of Psychoactive Drugs | <p>Most programs for alcohol and drug problems emphasize the importance of peer support, which is sometimes known as “mutual aid” (Borkman <xref rid="CIT0005" ref-type="bibr">1999</xref>) or “self-help” (Kurtz <xref rid="CIT0016" ref-type="bibr">1997</xref>; Riessman & Carroll <x... |
Long-term, treatment-free survival in select patients with distant metastatic papillary thyroid cancer | <p>Well-differentiated thyroid carcinoma (WDTC) generally has a favorable prognosis. However, patients with distant metastatic disease experience progression of disease with a higher mortality. A subset of patients not previously described may challenge the conventional dogma regarding the progressive nature of all met... | <contrib contrib-type="author"><name><surname>Kwong</surname><given-names>Norra</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Marqusee</surname><given-names>Ellen</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-... | Endocrine Connections | <sec sec-type="intro"><title>Introduction</title><p>Well-differentiated thyroid cancer is common, easily identified, and often curable. While the incidence of thyroid cancer has nearly tripled in the past three decades, mortality rates have remained stable <xref rid="bib1" ref-type="bibr">(1, 2, 3)</xref>. This undersc... |
Palliation in metastatic non-small cell lung cancer: Early integration with standard oncological care is the key | Could not extract abstract | <contrib contrib-type="author"><name><surname>Singh</surname><given-names>Navneet</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Behera</surname><given-names>Digambar</given-names></name><xref ref-type="aff" rid="aff1"/></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Lung cancer remains one of the most common malignancies globally (and within India also), amongst males as well as for both gender combined.[<xref rid="ref1" ref-type="bibr">1</xref><xref rid="ref2" ref-type="bibr">2</xref>] Approximately, 80% of cases are of non-small cell lung cancer (NSCLC) histology and present ... |
Laying the ground for research of interstitial lung disease in our country: ILD India registry | Could not extract abstract | <contrib contrib-type="author"><name><surname>Singh</surname><given-names>Virendra</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Sharma</surname><given-names>Bharat Bhushan</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib> | Lung India : Official Organ of Indian Chest Society | <p>India is a country with great diversity where dresses, dialects and diets vary drastically from place to place. But, above all there is a vast universality in thinking and emotions throughout India. Likewise, many chronic diseases have identical presentations, but with subtle and yet important regional differences.<... |
Utility of FDG-PET-CT scanning in assessing the extent of disease activity and response to treatment in sarcoidosis | <sec id="st1"><title>Background:</title><p>Radionuclide imaging modalities have increasingly been evaluated in the assessment of organ involvement in sarcoidosis. Fluoro-deoxyglucose positron emission tomography–computed tomography (FDG–PET–CT) scanning has received increasing attention in the r... | <contrib contrib-type="author"><name><surname>Guleria</surname><given-names>Randeep</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Jyothidasan</surname><given-names>Amudhan</given-names></name><xref ref-type="aff" rid="af... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Sarcoidosis is a chronic inflammatory multisystem disease that usually affects middle-aged adults and frequently presents with bilateral hilar lymphadenopathy, pulmonary parenchymal involvement and ocular and skin lesions. Diagnosis is established by a cli... |
Utility of noninvasive ventilation in high-risk patients during endoscopic retrograde cholangiopancreatography | <sec id="st1"><title>Background:</title><p>There is little evidence on noninvasive ventilation (NIV) preventing respiratory complications in high-risk patients undergoing endoscopy procedures.</p></sec><sec id="st2"><title>Objectives:</title><p>The objective of this study is to demonstrate that the application of NIV t... | <contrib contrib-type="author"><name><surname>Folgado</surname><given-names>Miguel Angel</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>De la Serna</surname><given-names>Carlos</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib><contrib co... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Endoscopic retrograde cholangiopancreatography (ERCP) with sedation and analgesia, performed by well-trained endoscopists, has proved to be a safe procedure, although significant complications may occur as a result of instrumentation or due to the effects ... |
Multidrug-resistant-tuberculosis treatment in the Indian private sector: Results from a tertiary referral private hospital in Mumbai | <sec id="st1"><title>Background:</title><p>There is very limited data on the experience and outcome of multidrug-resistant tuberculosis (MDR-TB) patients treated privately out of the DOTS plus program. Goal of this study is to provide characteristics and treatment outcomes of a prospective cohort of MDR-TB patients man... | <contrib contrib-type="author"><name><surname>Udwadia</surname><given-names>Zarir F.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Moharil</surname><given-names>Gautam</given-names></name><xref ref-type="aff" rid="aff1"/... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Tuberculosis (TB) is a major threat to world health. After HIV/AIDS, it is the most common cause of death from an infectious disease worldwide. A major obstacle to TB control is the emergence of mycobacterial resistance to anti-tuberculous chemotherapy.[<x... |
Correlation of exhaled nitric oxide, nasal nitric oxide and atopic status: A cross-sectional study in bronchial asthma and allergic rhinitis | <sec id="st1"><title>Objective:</title><p>Exhaled nitric oxide (FE<sub>NO</sub>) and nasal nitric oxide (n NO) measurement is an area of ongoing research in the study of airway inflammation. The atopic status is known to influence the levels of FE<sub>NO</sub> and n NO. This study was undertaken to study the relationsh... | <contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Nitesh</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Goel</surname><given-names>Nitin</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><na... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>The nitric oxide (NO) in the lung/airways has a key role as a vasodilator, bronchodilator, neurotransmitter and inflammatory mediator.[<xref rid="ref1" ref-type="bibr">1</xref><xref rid="ref2" ref-type="bibr">2</xref><xref rid="ref3" ref-type="bibr">3</xre... |
A comparative study of different dose fractionations schedule of thoracic radiotherapy for pain palliation and health-related quality of life in metastatic NSCLC | <sec id="st1"><title>Introduction:</title><p>To investigate the effect of different hypo fractionated thoracic radiotherapy schedules in relation to thoracic pain relief, overall survival and post radiotherapy HRQOL in metastatic NSCLC.</p></sec><sec id="st2"><title>Material and methods:</title><p>Stage IV NSCLC and ha... | <contrib contrib-type="author"><name><surname>Sau</surname><given-names>Sourav</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Sau</surname><given-names>Saikat</given-names></name><xref ref-type="aff" rid="aff2">1</xref></... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Metastatic non-small cell lung carcinoma (NSCLC) usually present with symptoms from the primary intra-thoracic tumor including dyspnea, chest pain, cough, and hemoptysis.[<xref rid="ref1" ref-type="bibr">1</xref>] Thoracic palliative radiotherapy is an eff... |
Spectrum of diffuse parenchymal lung diseases with special reference to idiopathic pulmonary fibrosis and connective tissue disease: An eastern India experience | <sec id="st1"><title>Objective:</title><p>To evaluate the clinical spectrum of diffuse parenchymal lung diseases (DPLD) encountered in the Indian setting and to compare idiopathic pulmonary fibrosis (IPF) and connective tissue disease associated DPLD (CTD-DPLD), the two commonest aetiologies.</p></sec><sec id="st2"><ti... | <contrib contrib-type="author"><name><surname>Kundu</surname><given-names>Somenath</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Mitra</surname><given-names>Subhra</given-names></name><xref ref-type="aff" rid="aff2">1</xref><xref ref-type="corresp" rid="cor... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Diffuse parenchymal lung diseases (DPLD) comprise a wide spectrum of disorders, with varied presentations and prognosis. Foremost among the known causes is the connective tissue disease (CTD), the others being occupational or environmental exposure and dru... |
Evaluation of the effect of pulmonary hydatid cyst location on the surgical technique approaches | <sec id="st1"><title>Purpose:</title><p>A hydatid cyst is the most common lung parasitic disease and is endemic in Iran. A hydatid cyst is more common in the right lung and lower lobes.</p></sec><sec id="st2"><title>Objective:</title><p>The aim of this study was to assess surgical treatment of pulmonary hydatid cysts a... | <contrib contrib-type="author"><name><surname>Sadrizadeh</surname><given-names>Ali</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Haghi</surname><given-names>Seyed Ziaollah</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type=... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Hydatid disease had been recognized since the Galen and Hipocrates, and in 1808 Rudolphi used the term hydatid cyst to describe echinococcosis in humans. A hydatid cyst is a parasitic infestation caused most commonly by echinococcal granulosus. The most co... |
Ease-of-use, preference, confidence, and satisfaction with Revolizer<sup>®</sup>, a novel dry powder inhaler, in an Indian population | <sec id="st1"><title>Context:</title><p>While prescribing an inhaler device, it is important to take into account the usability, preference, confidence, and satisfaction of the patients.</p></sec><sec id="st2"><title>Aims:</title><p>The present study assessed these parameters with Revolizer<sup>®</sup>, a novel... | <contrib contrib-type="author"><name><surname>Rajan</surname><given-names>Sujeet K.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Gogtay</surname><given-names>Jaideep A.</given-names></name><xref ref-type="aff" rid="aff2... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Administering drugs through the inhalation route is the most efficacious form of drug delivery in obstructive airway diseases (OADs) such as asthma and chronic obstructive pulmonary disease (COPD).[<xref rid="ref1" ref-type="bibr">1</xref>] In addition to ... |
Potential impact of fireworks on respiratory health | <p>The world-wide use of fireworks with their consequent detrimental effect on the air quality is widely recognized with elevated ambient air levels of particulate matter and its several metallic components and gases identified in several studies carried out during such events. Exposed individuals may be at risk follow... | <contrib contrib-type="author"><name><surname>Gouder</surname><given-names>Caroline</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Montefort</surname><given-names>Stephen</given-names></name><xref ref-type="aff" rid="aff1... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>The tradition of celebrating national and cultural events with fireworks is recognized the world over. For anyone who has enjoyed a spectacular fireworks display, a part of the scene was most definitely obscured by the cloud of smoke from the burning firew... |
Pleuro-peritoneal lymphomatosis with concurrent tonsillar involvement in T-cell nonHodgkin's lymphoma: Clinical presentation mimicking disseminated tuberculosis | <p>A young male patient had been evaluated for pleural effusion at another center wherein on the basis of exudative, lymphocyte predominant pleural effusion with high pleural fluid adenosine deaminase (ADA) levels and tuberculin skin test (TST) reactivity, antituberculous medications had been administered. Reevaluation... | <contrib contrib-type="author"><name><surname>Tiwari</surname><given-names>Pavan</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Madan</surname><given-names>Karan</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><n... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>In high prevalence countries, it is usual to consider a diagnosis of tuberculosis (TB) when the pleural/peritoneal fluid levels of adenosine deaminase (ADA) are elevated in the setting of an exudative pleural effusion/ascites with predominance of lymphocyt... |
Superior vena caval syndrome and ipsilateral pleural effusion: A rare presentation of anterior mediastinal thymoma | <p>Incidence of thymic malignancies is very low. Thymoma, a tumor of thymus gland, is of epithelial origin and is most common anterior mediastinal tumor. In most cases, thymomas are localized and locally advanced thymomas may rarely present with superior vena caval obstruction (SVCO) and malignant pleural deposits. Mic... | <contrib contrib-type="author"><name><surname>Das</surname><given-names>Anirban</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Pandit</surname><given-names>Sudipta</given-names></name><xref ref-type="aff" rid="aff1"/></co... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Thymoma is of epithelial origin arising from the epithelium of thymus gland. Incidence of thymic malignancies is 2.5-3.2/10,00,000 population.[<xref rid="ref1" ref-type="bibr">1</xref>] Thymoma comprises 20-25% of all mediastinal tumors and is most common ... |
Surgical lung biopsy to diagnose Behcet's vasculitis with adult respiratory distress syndrome | <p>A 34-year-old female presented with fever and abdominal pain. Past medical history includes Crohn's and Behcet's disease. Examination revealed multiple skin ulcerations, oral aphthae, and bilateral coarse rales. She developed respiratory distress with diffuse bilateral alveolar infiltrates on chest radiograph requir... | <contrib contrib-type="author"><name><surname>Vydyula</surname><given-names>Ravikanth</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Allred</surname><given-names>Charles</given-names></name><xref ref-... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Behcet's disease is an idiopathic vasculitis characterized by recurrent mucocutaneous ulcerations and uveitis. The diagnosis is made on the basis of clinical findings.[<xref rid="ref1" ref-type="bibr">1</xref><xref rid="ref2" ref-type="bibr">2</xref><xref ... |
Bilateral pleural effusion with APLA positivity in a case of rhupus syndrome | <p>Rhupus syndrome is a rare syndrome characterized by overlap of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Our patient was a diagnosed case of RA and developed SLE 2 years after. She was a middle-aged woman, presented with bilateral pleural effusion with exacerbation of skin and joint symptoms ... | <contrib contrib-type="author"><name><surname>Saha</surname><given-names>Kaushik</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Saha</surname><given-names>Arnab</given-names></name><xref ref-type="aff" rid="aff1"/></contr... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Rhupus syndrome is the combination of clinical and immunological features of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). The patients of this syndrome have features of RA at beginning and few years later the manifestations of SLE deve... |
Common variable immunodeficiency disorder - An uncommon cause for bronchiectasis | <p>Bronchiectasis continues to be a common respiratory problem of varied etiology. Common variable immunodeficiency disorder (CVID) is an uncommon cause for bronchiectasis. However, the prevalence of bronchiectasis remains very high in patients with CVID. This remains largely an underdiagnosed entity as primary immunod... | <contrib contrib-type="author"><name><surname>Panigrahi</surname><given-names>Manoj Kumar</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib> | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Bronchiectasis is a common respiratory disorder of diverse etiology. Usually, extensive investigation to identify the cause of bronchiectasis is not done in routine clinical practice as it is perceived to have little influence on its management. Convention... |
Granulomatosis with polyangitis with mononeuritis multiplex-immunosuppressives playing a double-edged sword | <p>A 52-year-old female was diagnosed with rheumatoid arthritis and was on methotrexate and prednisolone. She developed fever, cough, hemoptysis, and cavitary lesion on chest skiagram. She was put on antitubercular therapy without any improvement, meanwhile she developed painful right foot drop. Clinicoradiology and C-... | <contrib contrib-type="author"><name><surname>Mukherjee</surname><given-names>Subhasis</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Biswas</surname><given-names>Debabani</given-names></name><xref ref-type="aff" rid="aff... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Wegener's granulomatosis (WG), which has been recently renamed as Granulomatosis with polyangitis (GPA)[<xref rid="ref1" ref-type="bibr">1</xref><xref rid="ref2" ref-type="bibr">2</xref><xref rid="ref3" ref-type="bibr">3</xref>] is a systemic vasculitis in... |
Endobronchial ultrasound guided needle aspiration of a paraspinal mass with prior failed multiple diagnostic interventions: A case report and literature review | <p>The increasing frequency of tuberculosis (TB) in both developed and developing countries has continued to make spinal TB an important health problem. The present case report is about a patient who presented to us with progressive back pain and paraspinal mass. We performed endobronchial ultrasound guided needle aspi... | <contrib contrib-type="author"><name><surname>Sinha</surname><given-names>Nishant</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Padegal</surname><given-names>Vivek</given-names></name><xref ref-type="aff" rid="aff1"/></c... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Spinal involvement occurs in less than 1% of patients with tuberculosis (TB).[<xref rid="ref1" ref-type="bibr">1</xref><xref rid="ref2" ref-type="bibr">2</xref><xref rid="ref3" ref-type="bibr">3</xref>] Linear probe endobronchial ultrasound (EBUS), with th... |
Primary amyloidoma of lung treated with radiation: A rare case report | <p>Amyloidosis is a collection of diseases in which different proteins are deposited as insoluble beta-pleated sheets, disrupting organ function. Distribution of these deposits may be diffuse or localized throughout the body, depending on the pathophysiology of the underlying amyloid type. Isolated deposition of amyloi... | <contrib contrib-type="author"><name><surname>Kapoor</surname><given-names>Rakesh</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Bhattacharyya</surname><given-names>Tapesh</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Amyloidosis is a heterogenous group of disease characterized by deposition of misfolded insoluble proteins in extracellular space. Amyloidosis can be either primary or secondary, and deposition of those amyloid proteins can be systemic or localized. Locali... |
Shrinking lung syndrome in systemic lupus erythematosus-scleroderma overlap | <p>Shrinking lung syndrome (SLS) is a infrequently reported manifestation of systemic lupus erythematosus (SLE). Reported prevalence of SLS is about 0.5% in SLE patients. Pathogenesis is not fully understood and different therapeutic modalities have been employed with variable results, as only 77 cases of SLS have been... | <contrib contrib-type="author"><name><surname>Guleria</surname><given-names>Vivek S.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Singh</surname><given-names>Pradeep K.</given-names></name><xref ref-type="aff" rid="aff1... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Pleuropulmonary manifestations occur in 60-80% of patients with systemic lupus erythematosus (SLE), frequently in the form of pleuritis with or without pleural effusion, pneumonia, interstitial fibrosis, acute lupus pneumonitis and pulmonary hypertension.[... |
Pulmonary tumor thrombotic microangiopathy in an unknown primary cancer | <p>Pulmonary tumor thrombotic microangiopathy (PTTM) is a highly fatal complication of cancer leading to acute cor pulmonale and pulmonary hypertension. We present a case of 47-year-old male patient who developed acute breathlessness and died suddenly. The pulmonary vessels at autopsy on histopathologic examination sho... | <contrib contrib-type="author"><name><surname>Amonkar</surname><given-names>Gayathri P.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Jashnani</surname><given-names>Kusum D.</given-names></name><xref ref-type="aff" rid="... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Pulmonary tumor thrombotic microangiopathy (PTTM) also known as carcinomatosis endarteritis is a highly fatal respiratory complication seen in cases of malignancies especially adenocarcinomas of the stomach.[<xref rid="ref1" ref-type="bibr">1</xref><xref r... |
An extremely unusual presentation of isolated extrathoracic sarcoidosis of submandibular lymph node in a child | <p>A 12-year-old male child presented with left submandibular lymphadenopathy; excision biopsy revealed noncaseating granuloma with numerous Schaumann bodies in histopathology, suggestive of isolated extrathoracic sarcoidosis, which is an extremely rare entity in the pediatric age group.</p> | <contrib contrib-type="author"><name><surname>Agrawal</surname><given-names>Anand</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Singh</surname><given-names>Kulwant</given-names></name><xref ref-type="aff" rid="aff2">1</x... | Lung India : Official Organ of Indian Chest Society | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>A Norwegian dermatologist Caesar Boeck coined the term “sarcoidosis” in 1899.[<xref rid="ref1" ref-type="bibr">1</xref>] Although this disease affects all age groups, it usually develops before the age of 50 years with a peak incidence duri... |
Completely opaque hemithorax | Could not extract abstract | <contrib contrib-type="author"><name><surname>Chawla</surname><given-names>Rakesh K.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Madan</surname><given-names>Arun</given-names></name><xref ref-type="aff" rid="aff2">1</x... | Lung India : Official Organ of Indian Chest Society | <sec id="sec1-1"><title>CASE REPORT</title><p>A 45-year-old male patient, normotensive, non-diabetic, married with children, auto parts dealer by profession, presented to us with complaints of cough with expectoration, low grade fever and breathlessness from past 15 days. He gave no history of previous diseases or surg... |
Tracheal compression due to anomalous innominate artery in an adult | <p>A 47-year-old-female presented with dyspnea and unproductive cough for 4 months. General examination revealed pulsatile swelling in the midline below the thyroid cartilage present since childhood. Computed tomography-angiography of the neck showed right innominate artery dilated, elongated and coursing above downwar... | <contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Krishna B.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Tyagi</surname><given-names>Diksha</given-names></name><xref ref-type="aff" rid="aff1"/><... | Lung India : Official Organ of Indian Chest Society | <p>A 47-year-old-female presented in chest Outpatient Department with the chief complaint of unproductive cough and shortness of breath for 4 months that was insidious in onset and gradually progressive in nature. She never smoked and had no history of exposure to indoor air pollution. She was diagnosed to have hyperte... |
Eventration of the right hemidiaphragm with multiple associations: A rare presentation | Could not extract abstract | <contrib contrib-type="author"><name><surname>Mehrotra</surname><given-names>Ashok Kumar</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Vaishnav</surname><given-names>Khyati</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib><contrib contr... | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>Eventration of the diaphragm is mostly a congenital anomaly, where it is partly or wholly replaced by a fibrous sheet.[<xref rid="ref1" ref-type="bibr">1</xref>] The reported incidence of the disorder in adults is about 1:10,000. It usually occurs as an isolated entity and is extremely rare to occur bilat... |
A case of recurrent massive right sided pleural effusion-an unusual presentation of carcinoma prostate | Could not extract abstract | <contrib contrib-type="author"><name><surname>Bajpai</surname><given-names>Pranay Ashok</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Joshi</surname><given-names>Prakash</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="a... | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>Carcinoma prostate is the second most common cancer in males worldwide and hematological spread occurs commonly to bones, lung and liver. It has a typical pattern involving axial skeleton and loco regional lymph nodes specially obturator and hypogastric groups. Isolated visceral metastasis in absence of b... |
Protecting ourselves from tuberculosis. Describing a historic poster printed in italy on 1937 | Could not extract abstract | <contrib contrib-type="author"><name><surname>Inzirillo</surname><given-names>Francesco</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Giorgetta</surname><given-names>Casimiro</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-ty... | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>Pulmonary TB was the disease that spawned thoracic surgery and pulmonology. During the eighteenth and nineteenth centuries, the population shift to cities and the ensuing overcrowding contributed to TB being the most common cause of death. It was apparent that TB was a communicable disease but medical pro... |
An increasingly breathless patient | Could not extract abstract | <contrib contrib-type="author"><name><surname>Bodington</surname><given-names>Richard S.</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Faruqi</surname><given-names>Shoaib</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>We read the recent article by Karkhanis and colleagues entitled “Flow volume loops as a diagnostic marker” with great interest.[<xref rid="ref1" ref-type="bibr">1</xref>] The authors describe the case of a young girl who developed exertional dyspnea after a period of mechanical ventilation... |
Mobile vegetation leading to septic pulmonary embolism | Could not extract abstract | <contrib contrib-type="author"><name><surname>Haider</surname><given-names>Imran</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Raghav</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><... | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>A 42-year-old Caucasian female with a prolonged history of intravenous (IV) methamphetamine abuse presented with high-grade fever, progressively worsening productive cough, dyspnea, myalgia, arthralgia and intermittent confusion for 1 week. The initial laboratory assessment showed leukocytosis, thrombocyt... |
Relationship between lung function and indoor air pollution | Could not extract abstract | <contrib contrib-type="author"><name><surname>Yasri</surname><given-names>Sora</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Wiwanitkit</surname><given-names>Viroj</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>The recent report on the, ‘Relationship between lung function and indoor air pollution’ among rural women in the fishing community is very interesting.[<xref rid="ref1" ref-type="bibr">1</xref>] Umoh and Peters noted that ‘chronic exposure to biomass smoke is associated with chroni... |
Author's reply | Could not extract abstract | <contrib contrib-type="author"><name><surname>Umoh</surname><given-names>Victor Aniedi</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Petersa</surname><given-names>Etete</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Sir</p><p>This is a response to the queries raised in a Letter to the Editor[<xref rid="ref1" ref-type="bibr">1</xref>] concerning the article titled, ‘The relationship between lung function and indoor air pollution among rural women in the Niger Delta region of Nigeria.’ The authors of the letter ra... |
Bhang - beyond the purview of the narcotic drugs and psychotropic substances act | Could not extract abstract | <contrib contrib-type="author"><name><surname>Balhara</surname><given-names>Yatan Pal Singh</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Mathur</surname><given-names>Shachi</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>In the publication titled ‘Medical marijuana: A panacea or scourge’ the authors have reviewed an important and widely debated issue.[<xref rid="ref1" ref-type="bibr">1</xref>] The authors have stated that ‘<italic>in India, as per the Narcotic Drugs and Psychotropic Substances Act,... |
Author's reply | Could not extract abstract | <contrib contrib-type="author"><name><surname>Kashyap</surname><given-names>Surender</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Kashyap</surname><given-names>Kartikeya</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>We acknowledge the comments[<xref rid="ref1" ref-type="bibr">1</xref>] regarding our article published in Lung India.[<xref rid="ref2" ref-type="bibr">2</xref>] We agree with the author that <italic>Bhang</italic>, which consists of cannabis leaves, is not included under the purview of the Narcotic Drugs ... |
Adenosine deaminase in exudative pleural effusions | Could not extract abstract | <contrib contrib-type="author"><name><surname>Wiwanitkit</surname><given-names>Somsri</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Wiwanitkit</surname><given-names>Viroj</given-names></name><xref ref-type="aff" rid="aff2">1</xref></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>The report on ‘Adenosine Deaminase in Exudative Pleural Effusions’ is very interesting.[<xref rid="ref1" ref-type="bibr">1</xref>] Mehta <italic>et al</italic>. have concluded that ‘pleural fluid adenosine deaminase (ADA) is cost-effective and a good screening test for the diagnosi... |
Author's reply | Could not extract abstract | <contrib contrib-type="author"><name><surname>Mehta</surname><given-names>Asmita Anilkumar</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Amit Satish</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-... | Lung India : Official Organ of Indian Chest Society | <p>We would like to thank Wiwanitkit <italic>et al</italic>., for their interest in our study and their valuable observations.</p><p>In response to the authors’ comments about the reported lower predictive value of the adenosine deaminase (ADA) test in our article,[<xref rid="ref1" ref-type="bibr">1</xref>] we ... |
Comments on non-utilising of rapid onsite evaluation with transbronchial needle aspiration | Could not extract abstract | <contrib contrib-type="author"><name><surname>Sindhwani</surname><given-names>Girish</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Khanduri</surname><given-names>Rakhee</given-names></name><xref ref-type="aff" rid="aff1"/></contrib> | Lung India : Official Organ of Indian Chest Society | <p>Sir,</p><p>This communication is regarding an article e-published in the July-September 2014 issue of your journal. The article is entitled ‘Diagnostic utility of conventional transbronchial needle aspiration without rapid onsite evaluation in patients with lung cancer,’ by Ritika Walia <italic>et al... |
Quantum magnetic phase transition in square-octagon lattice | <p>Quantum magnetic phase transition in square-octagon lattice was investigated by cellular dynamical mean field theory combining with continuous time quantum Monte Carlo algorithm. Based on the systematic calculation on the density of states, the double occupancy and the Fermi surface evolution of square-octagon latti... | <contrib contrib-type="author"><name><surname>Bao</surname><given-names>An</given-names></name><xref ref-type="aff" rid="a1">1</xref><xref ref-type="aff" rid="a2">2</xref></contrib><contrib contrib-type="author"><name><surname>Tao</surname><given-names>Hong-Shuai</given-names></name><xref ref-type="aff" rid="a3">3</xre... | Scientific Reports | <p>The discovery and classification of quantum phases of matters and the transition between these distinctive phases have been recurring theme in condensed matter physics for many years and still wheel the researchers' extensive interests<xref ref-type="bibr" rid="b1">1</xref><xref ref-type="bibr" rid="b2">2</xref><xre... |
A time of change | Could not extract abstract | <contrib contrib-type="author"><name><surname>Kumar</surname><given-names>Santosh</given-names></name><xref ref-type="aff" rid="aff1"/></contrib> | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <p>We are going through a time of change. Apart from the ones affecting the journal and national politics, about 3 years back, there was a paradigm shift in the government policy on medical education with an emphasis on specialist training. This resulted in a sudden increase of post-graduate training positions in surgi... |
Is it truly outrageous to consider radical prostatectomy for men with metastatic prostate cancer? | <p>Radical prostatectomy is a leading form of treatment for non metastatic prostate cancer. It has been shown to improve survival in the long term as well as delay or prevent the onset of metastatic disease. However, as the treatment of metastatic prostate cancer has evolved in the last few years with the introduction ... | <contrib contrib-type="author"><name><surname>Gautam</surname><given-names>Gagan</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib> | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <p>Radical prostatectomy (RP) is a leading treatment option for clinically organ confined prostate cancer (CaP) in men with a life expectancy greater than 10-15 years.[<xref rid="ref1" ref-type="bibr">1</xref>] Of late, there is growing evidence to suggest that patients with high-risk and/or locally advanced disease ma... |
Commenatry on Gautam G. Is it truly outrageous to consider radical prostatectomy for men with metastatic prostate cancer? Indian J Urol 2014;30:366-7 | Could not extract abstract | <contrib contrib-type="author"><name><surname>Panda</surname><given-names>Arabind</given-names></name><xref ref-type="aff" rid="aff1"/></contrib> | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <p>The concept of radical prostatectomy for metastatic prostate cancer is interesting. The rationale of debulking in metastatic cancer is derived from the experience in gastric and ovarian carcinomas where debulking and systemic chemotherapy have shown a survival benefit. The essential difference between adenocarcinoma... |
Painful varicoceles: Role of varicocelectomy | <p>The incidence of varicocele in the general population is up to 15%. It is estimated that the prevalence of pain with varicoceles is around 2-10%. Till the year 2000, only two studies evaluated efficacy of varicocelectomy in painful varicoceles with conflicting results. Over the past decade many other studies have ad... | <contrib contrib-type="author"><name><surname>Abrol</surname><given-names>Nitin</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Panda</surname><given-names>Arabind</given-names></name><xref ref-type="aff" rid="aff1"/></con... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Varicoceles are detectable in approximately 15% of general adult male population.[<xref rid="ref1" ref-type="bibr">1</xref>] While pain was the earlier indication for varicocelectomy and its role in infertility was recognized later, there is more literatur... |
Continence outcomes following robotic radical prostatectomy: Our experience from 150 consecutive patients | <sec id="st1"><title>Introduction:</title><p>Urinary continence is an important outcome parameter after robot assisted radical prostatectomy (RARP). We evaluated the continence outcomes following RARP using a double-layered urethrovesical reconstruction.</p></sec><sec id="st2"><title>Materials and Methods:</title><p>On... | <contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Narmada P.</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Yadav</surname><given-names>Rajiv</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Prostate cancer is the most common cancer diagnosed in men and the second most common cause of death from cancer in industrialized countries. In India, the incidence of prostate cancer is second among all the cancers in men and a rising mean annual percent... |
Changes in pathologic outcomes and operative trends with robot-assisted laparoscopic radical prostatectomy | <sec id="st1"><title>Introduction:</title><p>We hypothesized that there is a reverse stage migration, or a shift toward operating on higher-risk prostate cancer, in patients undergoing robot-assisted laparoscopic prostatectomy (RALP). We therefore evaluated the stage of disease at the time of surgery for patients with ... | <contrib contrib-type="author"><name><surname>Bernie</surname><given-names>Aaron</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Ramasamy</surname><given-names>Ranjith</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/><... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Although Prostate-specific antigen (PSA) testing for prostate cancer screening has lowered death rates due to prostate cancer,[<xref rid="ref1" ref-type="bibr">1</xref>] there is growing concern that clinically insignificant prostate cancer would be detect... |
Practical approach to screen vesicoureteral reflux after a first urinary tract infection | <sec id="st1"><title>Introduction:</title><p>Vesicoureteral reflux (VUR) is a common pediatric urologic disorder. After the first urinary tract infection (UTI), imaging studies are recommended, starting with a renal ultrasound (RUS). Voiding cystourethrography (VCUG) and dimercaptosuccinic acid (DMSA) scan are the othe... | <contrib contrib-type="author"><name><surname>Fuente</surname><given-names>María Álvarez</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Costa</surname><given-names>Talía Sainz</given-names></name><... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Urinary tract infection is a very common condition in pediatric patients, affecting up to 2% of children in their first year of life.[<xref rid="ref1" ref-type="bibr">1</xref>] On an average 30-40% of children with their first UTI episode have associated V... |
Efficacy of nifedipine and alfuzosin in the management of distal ureteric stones: A randomized, controlled study | <sec id="st1"><title>Introduction:</title><p>Stone disease is a significant and world-wide health problem. Recently, certain drugs have been used as a supplement to observation alone in an effort to improve spontaneous stone expulsion. We evaluated the efficacy of nifedipine and alfuzosin in the medical treatment of sy... | <contrib contrib-type="author"><name><surname>Sameer</surname><given-names/></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Lal</surname><given-names>Shyam</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Urinary stone disease is a common condition affecting up to 12% of the world population. A large number of patients presenting in surgical emergency have symptoms and signs of ureteric colic. Many of these patients suffer from distal ureteric stones (70%).... |
Outcome of tubularized incised plate urethroplasty with spongioplasty alone as additional tissue cover: A prospective study | <sec id="st1"><title>Introduction:</title><p>Additional cover after neourethra formation to decrease the fistula rate, has been described using the dartos, tunica, denuded skin and corpus spongiosum. The use of corpus spongiosum alone to cover the neourethra is infrequent. The objective of this study was to evaluate th... | <contrib contrib-type="author"><name><surname>Bhat</surname><given-names>Amilal</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Sabharwal</surname><given-names>Karamveer</given-names></name><xref ref-type="aff" rid="aff1"/... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>The tubularized incised plate urethroplasty (TIPU) repair is the procedure of choice for distal and mid-shaft hypospadias and is increasingly being used for proximal hypospadias and redo repairs.[<xref rid="ref1" ref-type="bibr">1</xref><xref rid="ref2" re... |
Current concepts in robotic radical prostatectomy | Could not extract abstract | <contrib contrib-type="author"><name><surname>Gupta</surname><given-names>Narmada P</given-names></name><xref ref-type="aff" rid="aff1"/></contrib> | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <p>The pioneering contributions of Dr Patrick Walsh on the anatomic dissection for preservation of the neurovascular bundles (NVBs) remain one of the most significant landmarks in urological history. He also described “Anatomical Radical Prostatectomy” on the basis of the venous drainage, arterial and n... |
Newer concepts in neural anatomy and neurovascular preservation in robotic radical prostatectomy | <p>With more than 60% of radical prostatectomies being performed robotically, robotic-assisted laparoscopic prostatectomy (RALP) has largely replaced the open and laparoscopic approaches and has become the standard of care surgical treatment option for localized prostate cancer in the United States. Accomplishing negat... | <contrib contrib-type="author"><name><surname>Pisipati</surname><given-names>Sailaja</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Ali</surname><given-names>Adnan</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author">... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>The introduction of prostate-specific antigen (PSA) screening over the last two decades has resulted in stage migration of prostate cancer.[<xref rid="ref1" ref-type="bibr">1</xref>] Radical prostatectomy (RP) for organ-confined prostate cancer is an effec... |
Role of robot-assisted radical prostatectomy in the management of high-risk prostate cancer | <p>We aimed to evaluate the role of robot-assisted radical prostatectomy (RARP) in the management of high-risk prostate cancer (PCa), with a focus on oncological, functional and perioperative outcomes. Further, we also aimed to briefly describe our novel modification to conventional RARP that allows immediate organ ret... | <contrib contrib-type="author"><name><surname>Sood</surname><given-names>Akshay</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Jeong</surname><given-names>Wooju</given-names></name><xref ref-type="aff" rid="aff1"/></contr... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Prostate-specific antigen (PSA) screening was introduced in the US in the late 1980s for early detection of prostate cancer (PCa), and has resulted in both an increase in PCa diagnoses and an earlier identification of these tumors. Despite the downward sta... |
Handling difficult anastomosis. Tips and tricks in obese patients and narrow pelvis | <p>Vesico-urethral anastomosis (VUA) is a technically challenging step in robotic-assisted laparoscopic prostatectomy (RALP) in obese individuals. We describe technical modifications to facilitate VUA encountered in obese individuals and in patients with a narrow pelvis. A Pubmed literature search was performed between... | <contrib contrib-type="author"><name><surname>Samavedi</surname><given-names>Srinivas</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Abdul-Muhsin</surname><given-names>Haidar</given-names></name><xref ref-type="aff" rid="... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Prostate cancer is the most common non-cutaneous solid malignancy among men in the United States and the second leading cause of cancer death.[<xref rid="ref1" ref-type="bibr">1</xref>] With the advent of new diagnostic advances and early screening, more t... |
Significance and management of positive surgical margins at the time of radical prostatectomy | <p>Positive surgical margins (PSM) at the time of radical prostatectomy (RP) result in an increased risk of biochemical recurrence (BCR) and secondary treatment. We review current literature with a focus on stratifying the characteristics of the PSM that may define its significance, the impact of modern imaging and sur... | <contrib contrib-type="author"><name><surname>Silberstein</surname><given-names>Jonathan L.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Eastham</surname><given-names>James A.</given-names></name><xref ref-type="aff" ri... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Wide variations in the incidence of positive surgical margins (11-48%) have been reported at the time of radical prostatectomy (RP).[<xref rid="ref1" ref-type="bibr">1</xref><xref rid="ref2" ref-type="bibr">2</xref><xref rid="ref3" ref-type="bibr">3</xref>... |
Salvage robotic radical prostatectomy | <p>Failure of non-surgical primary treatment for localized prostate cancer is a common occurrence, with rates of disease recurrence ranging from 20% to 60%. In a large proportion of patients, disease recurrence is clinically localized and therefore potentially curable. Unfortunately, due to the complex and potentially ... | <contrib contrib-type="author"><name><surname>Kaffenberger</surname><given-names>Samuel D.</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Smith</surname><given-names>Joseph A.</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid=... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Radical prostatectomy and radiation therapy remain the mainstays of primary treatment for clinically localized prostate cancer. Recurrence after primary therapy failure represents a significant and common clinical dilemma, with rates of prostate cancer rec... |
Erectile dysfunction in robotic radical prostatectomy: Outcomes and management | <p>Robot-assisted laparoscopic prostatectomy (RALP) has emerged as the most common treatment for localized prostate cancer. With improved surgical precision, RALP has produced hope of improved potency rates, especially with the advent of nerve-sparing and other modified techniques. However, erectile dysfunction (ED) re... | <contrib contrib-type="author"><name><surname>Whelan</surname><given-names>Patrick</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Ekbal</surname><given-names>Shahid</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Prostate cancer (CaP) remains the most common malignancy in men in the United States.[<xref rid="ref1" ref-type="bibr">1</xref>] Retropubic radical prostatectomy (RRP) remains the gold standard for locally invasive disease;[<xref rid="ref2" ref-type="bibr"... |
Ureteritis cystica: A rare entity in children | <p>Ureteritis cystica (UC) is a benign condition. Although it can often be diagnosed with imaging techniques, we report a case of a child for whom we planned nephrectomy and ureteral augmentation cystoplasty, but abandoned the cystoplasty due to extensive UC in the ureter.</p> | <contrib contrib-type="author"><name><surname>Dönmez</surname><given-names>M. İrfan</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Beksaç</surname><given-names>A. Tuna</given-names></name><xref ref... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Ureteritis cystica (UC) is a benign pathology, which develops following chronic inflammation. A variety of diseases with obstruction and chronic inflammation may lead to UC. Although a diagnosis is often made with imaging techniques, we report a case of a ... |
Small bowel intussusception due to metastatic bladder carcinoma | <p>The common sites of metastasis from a urinary bladder carcinoma include lymph nodes, bones, lung, liver, and peritoneum. Only a few cases of small bowel metastasis from urinary bladder malignancy have been reported in the English literature. Only one of these cases presented with bowel intussusception. We report a c... | <contrib contrib-type="author"><name><surname>Singh</surname><given-names>Seema</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Ranjan</surname><given-names>Rakesh</given-names></name><xref ref-type="aff" rid="aff1"/></con... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Small bowel intussusception is seen more commonly in pediatric population as compared to adults. Adult small bowel intussusceptions occur almost always due to a demonstrable lead point, mostly benign, at times malignant.[<xref rid="ref1" ref-type="bibr">1<... |
Arteriovenous malformation causing obstructive uropathy: A different dimension to ovarian vein syndrome | <p>Ovarian vein syndrome is defined as obstructive uropathy caused by dilated ovarian vein with or without thrombosis. This is seen in the puerperal period as an acute condition with abdominal pain and fever and in multipara women with chronic recurrent abdominal pain. We report an ovarian vein syndrome caused by a tru... | <contrib contrib-type="author"><name><surname>Kone</surname><given-names>Kalyana Ram</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib> | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Ovarian vein syndrome is defined as ureteric obstruction caused by dilated ovarian vein with or without thrombosis and is a controversial and rare diagnosis. All cases reported so far are in adults where an abnormal gonadal vein compressed the ureter and c... |
Massive left hemothorax following laparoscopic pyeloplasty | <p>Laparoscopic pyeloplasty is viable standard minimally invasive alternative to open pyeloplasty for the treatment of ureteropelvic junction obstruction. Intrathoracic bleeding is an extremely rare complication after laparoscopic urological surgery, but it should be suspected and promptly diagnosed in case of worsenin... | <contrib contrib-type="author"><name><surname>Rao</surname><given-names>Manjula</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>D’Souza</surname><given-names>Nischith</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="c... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Laparoscopic pyeloplasty (LP) is a minimally invasive alternative to open pyeloplasty for the treatment of ureteropelvic junction obstruction. It has been shown to provide lower patient morbidity, shorter hospitalization and faster convalescence. However, ... |
Spontaneous perinephric hemorrhage (Wunderlich syndrome) secondary to polyarteritis nodosa: Computed tomography and angiographic findings | <p>We report the case of a young man who presented with spontaneous left perinephric hematoma and per-rectal bleeding. Evaluation revealed renal and superior mesenteric arterial aneurysms secondary to polyarteritis nodosa (PAN). Computed tomography and angiographic findings are presented. The aetiology of spontaneous p... | <contrib contrib-type="author"><name><surname>Venkatramani</surname><given-names>Vivek</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Banerji</surname><given-names>John S.</given-names></name><xref ref-type="aff" rid="aff... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <p>Spontaneous perinephric hematoma is a rare entity with malignancies being the most common cause.[<xref rid="ref1" ref-type="bibr">1</xref>] Vasculites are the next most common cause, and of these polyarteritis nodosa (PAN) accounts for most cases.[<xref rid="ref1" ref-type="bibr">1</xref>] We report the case of a yo... |
“The creeping tumor:” An unusual presentation of upper urinary tract malignancy | <p>Upper urinary tract urothelial malignancy accounts for 5-10% of urothelial carcinomas. Synchronous bladder carcinoma occurs in 2-4% of patients with upper urinary tract tumors. Urothelial malignancy involving the entire upper urinary tract is an extremely rare entity. Most upper urinary tract malignancies are transi... | <contrib contrib-type="author"><name><surname>Selvaraj</surname><given-names>Velaiyan</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name><surname>Govindarajan</surname><given-names>Periasamy</given-names></name><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <sec sec-type="intro" id="sec1-1"><title>INTRODUCTION</title><p>Transitional cell carcinomas (TCC) spread along the urothelial cellular lining. However, presentation of TCC involving the entire upper urinary tract is extremely rare, and, to the best of our knowledge, this is the first case reported.[<xref rid="ref1" re... |
Re: Parikh GP, Sonde SR, Kadam P. Venous air embolism: A complication during percutaneous nephrolithotomy. Indian J Urol 2014;30:348-9 | Could not extract abstract | <contrib contrib-type="author"><name><surname>Ozturk</surname><given-names>Hakan</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib> | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <p>Dear Editor,</p><p>With reference to the recent article on venous air embolism during percutaneous nephrolithotomy published in your journal,[<xref rid="ref1" ref-type="bibr">1</xref>] we would like to reiterate that air embolism is a very rare and important complication that should always be kept in mind by endouro... |
Re: Sabharwal S, Macaden AR, Abrol N, Mukha RP, Kekre NS. A novel computer based stent registry to prevent retained stents: Will patient directed automated short message service and letter generator help? Indian J Urol 2014;30:150-2 | Could not extract abstract | <contrib contrib-type="author"><name><surname>Modi</surname><given-names>Jayesh</given-names></name><xref ref-type="aff" rid="aff1"/><xref ref-type="corresp" rid="cor1"/></contrib><contrib contrib-type="author"><name><surname>Nagarajan</surname><given-names>Ramya</given-names></name><xref ref-type="aff" rid="aff1"/></c... | Indian Journal of Urology : IJU : Journal of the Urological Society of India | <p>Dear Editor,</p><p>We have read the original article titled “A novel computer based stent registry to prevent retained stents: Will patient directed automated short message service and letter generator help?” by Sabharwal <italic>et al</italic>., with great interest.[<xref rid="ref1" ref-type="bibr">... |