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More than half of new cases of cancer are diagnosed in patients over 65 years. However only few elderly patients have so far been included into trials, despite general awareness of the need. The revolution of immune checkpoint blocker development brings new hope in older patients because of clinical efficacy and low toxicity. Clinical indications are rising steadily but very few data are available in this population where co-morbidities, reduced functional reserve and immunosenescence may affect efficacy and tolerance. All cases of patients enrolled in immunotherapy phase I trial between January 2012 and December 2016 in the Drug Development Department (DITEP) at Gustave Roussy were retrospectively reviewed. Case-control analysis was performed in a group of patients ≥ 70 years (elderly patients EP) matched to a group of patients < 70 years (younger patients YP) by trial and treatment dose. We compared cumulative incidence, grade and type of adverse events (AEs) and survival outcomes. Cumulative incidence was calculated according to Fine and Gray method and survivals using Kaplan-Meier method. Median age of EP and YP were respectively 75 (70 - 88) and 55 (22 - 70). Among the 46 EP and the 174 YP enrolled in 13 protocols, 10 (22%) and 23 (13%) patients experienced grade 3-4 AEs. Cumulative incidence of grade 1-2 AEs was significantly higher in EP versus YP (p Immune checkpoint blockade appears to be a practicable option of treatment for elderly patients. The toxicity and efficacy profiles appear similar to the ones in younger patients. Dedicated studies in this population are warranted. Clinical trial identification Legal entity responsible for the study All authors have declared no conflicts of interest.
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FRANKLIN, Tenn., April 19, 2021 /PRNewswire/ -- One in three pets will be lost at some point in their life1, making losing a pet one of the biggest concerns pet parents face. In fact, 10 million pets are reported lost or stolen in the U.S. every year1. As a solution to help reunite more lost dogs with their families – and in honor of National Pet ID Week (April 17-23) – the IAMS brand is launching the beta version of the new NOSEiD mobile app today, available throughout Nashville and the surrounding area. The NOSEiD app uses first-of-its-kind nose-scanning smartphone technology to help identify lost dogs by their nose print, which is unique to each dog, much like a human fingerprint2. The app's nose-detection technology is paired with the support of local communities to help reunite lost dogs with their pet parents. "Pets are irreplaceable family members, and with the NOSEiD app, we're hoping to help keep more pets in their loving homes and out of shelters – taking another step toward our goal of ending pet homelessness," said Craig Neely, Vice President of Marketing at Mars Petcare. "The app is designed to be a community resource, so whether someone has a dog or not, they'll be able to join the NOSEiD community to help reunite lost dogs with their families in their own neighborhood." The NOSEiD app provides any person who finds a lost dog the tools they need to reunite it with its family, right in their smartphone. In addition to using the unique nose print of each dog as part of their pet profile, the app provides resources for pet parents and community members, such as an interactive map of lost dogs, robust pet profiles, a lost dog poster generator and more. Here's how the NOSEiD app works: - Pet parents can download the app and follow the prompts on the screen to make a profile for their dog, including scans of their dog's nose and a physical description. - If a dog goes missing, the pet parent can report their dog as lost, and the missing dog alert will instantly be sent to other NOSEiD app users in their community. - Anyone who finds a lost dog can use the app to check the lost dog profiles in the community, as well as scan the found dog's nose to search the NOSEiD app for any matches. Once the dog has been identified, the finder can connect with the pet parent to reunite them with their dog. With the new NOSEiD solution, the IAMS brand, which is part of the Mars Petcare portfolio of products and services, is working to support the company's global ambition to end pet homelessness. The brand will work with local animal shelter partners to educate new pet parents on the need for the NOSEiD app and how it can be beneficial, in addition to other preventative measures like microchipping. The brand also will be collaborating with local businesses throughout Nashville, such as groomers, restaurants, shops, dog walkers and more, to spread the word about the new technology. The NOSEiD app is available for Apple and Android devices in the App Store and Google Play Store. For more information on the NOSEiD app, visit IAMS.com/NOSEiD and follow along on the NOSEiD Facebook channel. Interested users can download the app or visit the website to sign up for emails to be notified when the NOSEiD app is available in their city. # # # About the IAMS™ Brand The IAMS™ brand is dedicated to helping dogs and cats live happy, healthy lives and believes high-quality nutrition truly makes a difference. IAMS is driven to create pet-specific nutritional solutions that are tailored across every life-stage, pet size and health need. Through years observing the behavior of dogs and cats, combined with research and dietary findings, the IAMS brand believes that the right diet can help pets boost immunity, burn fat and maintain muscle, and promote healthy digestion. IAMS products are made with high-quality ingredients and unique, patented recipes that give your pet our best nutrition possible. When you choose IAMS dog or cat food, you're choosing high-quality food that will help you see visible differences in your furry friend. For more information, visit IAMS.com. About Mars Petcare Part of Mars, Incorporated, a family-owned business with more than a century of history making diverse products and offering services for people and the pets people love, the 85,000 Associates across 50+ countries in Mars Petcare are dedicated to one purpose: A BETTER WORLD FOR PETS™. With 85 years of experience, our portfolio of almost 50 brands serves the health and nutrition needs of the world's pets – including brands PEDIGREE®, WHISKAS®, ROYAL CANIN®, NUTRO™, GREENIES™, SHEBA®, CESAR®, IAMS™ and EUKANUBA™ as well as the WALTHAM Petcare Science Institute which has advanced research in the nutrition and health of pets for over 50 years. Mars Petcare is also a leading veterinary health provider through an international network of over 2,000 pet hospitals and diagnostic services including BANFIELD™, BLUEPEARL™, VCA™, Linnaeus, AniCura and Antech. We're also active in innovation and technology for pets, with WISDOM PANEL™ genetic health screening and DNA testing for dogs, the WHISTLE™ GPS dog tracker, and LEAP VENTURE STUDIO accelerator and COMPANION FUND™ programs that drive innovation and disruption in the pet care industry. As a family business and guided by our principles, we are privileged with the flexibility to fight for what we believe in – and we choose to fight for: A BETTER WORLD FOR PETS. SOURCE The IAMS™ Brand
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Return to Transcripts main page The Situation Room Omaha Mall Shootings; Iran's Nuclear Program; Terror Suspects Fight for Rights; Clinton Vote on Iran a "Mistake"; State of Emergency in Northwest; Modern-Day "Bonnie and Clyde" Aired December 05, 2007 - 17:00 ET THIS IS A RUSH TRANSCRIPT. THIS COPY MAY NOT BE IN ITS FINAL FORM AND MAY BE UPDATED. BLITZER: But let's begin with the breaking news. We're getting new details on that story we have been following for the past couple of hours. Multiple shots fired inside a mall department store in Omaha, Nebraska. There are now believed to be at least five victims, with two of them now reported dead. Carol Costello is monitoring developments for us for us. She's joining us now with the latest. What do we know -- Carol. CAROL COSTELLO, CNN CORRESPONDENT: Yes, Wolf. As far as we know right now, police in Omaha, Nebraska still searching that mall, going from store to store, searching for a gunman, someone -- either one or two people -- opened fire inside of that department store you were talking about, called Von Maur. And, according to witnesses, shot one man in the head and another man on a cell phone who was calling 911. Hospital officials are saying now that a man and woman are dead and there is another woman in the hospital right now in critical condition. Other witnesses inside the store told us they heard five or six shots. Other witnesses said they heard 20 to 30 shots. We saw at least two people taken from the mall on stretchers. We're hearing at least five or more people have been injured besides those that dead that I told you about. Now, as I said, police are still going store to store. So some people reportedly are still holed up inside that mall, hiding in back rooms. The mall is locked down until police can wrap this thing up. Witnesses do say they saw some shoppers coming from the mall with hands on top of their head. And that's probably because police want to get them out of the mall and they want to make sure those people are not the gunman, so they're telling them to put their hands on their head. We do know, Wolf, as you said, a man and woman dead. That's according to hospital officials. And one woman is in very critical condition. Five or more injured -- maybe up to 10. We just don't know. One local affiliate reporting that there was a man in handcuffs outside of the mall wearing a black sweatshirt with his hood up. We don't know if he was connected to that shooting. Another witness said that he thought he saw the gunman try to commit suicide and fail. We don't know if that report is true, either. Police are being very tight-lipped about this. And as I said, as I get more information, I'll be glad to pass it along. BLITZER: All right, stand by for a moment, Carol, because I want to play some eyewitness accounts of what people saw and heard as this was unfolding. Listen to this. (BEGIN VIDEO CLIP) UNIDENTIFIED MALE: We were in the center part of the mall. And with all the construction going off, it sounded like nail guns and whatnot going off. But then people just started running frantically, saying there's been a shooting in there. And I gathered my wife and kids and got out as soon as possible. UNIDENTIFIED FEMALE: I'm just still in shock. I can't believe it. I mean I came here for an hour just -- I had an hour of extra time before I picked up my son from school and I was going to grab a few presents. And my daughter says, maybe they're doing construction downstairs, mom. And I thought that at first. And then the second time we just -- it was too much. (END VIDEO CLIP) BLITZER: We're also getting this from the Associated Press now, moving a story, quoting the major newspaper in Omaha. The "Omaha World-Herald" is reporting that at least five people are now reported dead and a dozen others wounded after this shooting at this mall in Omaha. I want to go back to Carol. Costello. She's getting this information, as well. The A.P. quoting the "Omaha World-Herald," saying at least five people now reported dead, a dozen others wounded. This is a serious -- this is a serious development that's unfolding. And you know what, Carol, for a moment, let's listen in to our affiliate, as it's reporting live on what they're saying right now. UNIDENTIFIED MALE: They have just been able to go inside, grab their things, their purse, whatever they left inside. They are finally going inside to grab it and leave. But that wasn't the case around 1:30, 2:00 this afternoon. Customers told me it was chaos -- as well as employees. They said they heard more than 15 gunshot wounds -- or gunshots. I'm sorry. People were ducking, hiding, going into restrooms, fitting rooms, wherever they can to hide away. One of the customers told me when she heard the gunshots, she looked up and all she saw was a cloud of smoke. It took about a half an hour for police to go inside and let them out. But one of the employees -- one of the managers told me when she heard the gunshots, she turned around and she saw several people down -- laying down on the ground, shot with gunshot wounds. Now, there are still people inside trying to get some of their stuff out. People are -- when people heard the gunshots, they actually didn't believe that they were gunshots. They said they thought it was construction going on. They didn't -- they didn't know what was going on. But when they realized it was gunshots, they practically ran and hid. UNIDENTIFIED FEMALE: Bill Mulai (ph) reporting for us. Right now, I understand that Bill can't hear us, so we're going to go ahead and try to get back to him as soon as possible... UNIDENTIFIED MALE: Right. UNIDENTIFIED FEMALE: ...when he can hear us. UNIDENTIFIED MALE: Now, some of that video that you just saw right there was some unedited video we had just gotten back to our studios. UNIDENTIFIED FEMALE: Yes. UNIDENTIFIED MALE: You really got a feel for what the situation was like early on in this shooting at Westroads Mall. UNIDENTIFIED FEMALE: Really some dramatic pictures. And earlier on, when were on the air, we talked to a Von Maur employee. She painted a dramatic picture herself before we even had those pictures. She was actually inside the Von Maur store when that shooting happened. UNIDENTIFIED MALE: And then she actually witnessed one of the people get shot. She was on the first floor in the cosmetics department. UNIDENTIFIED FEMALE: Right. UNIDENTIFIED MALE: That's where she works, in Von Maur, in the cosmetics department. That is on the west side of the store. She heard the gunshots that have been described very well by many people and then saw one of her employees -- co-workers go down. Lisa Bottle (ph) is her name. She's going to describe to us what she saw, in an interview we had earlier for you, during our coverage earlier this afternoon. (BEGIN VIDEO TAPE) UNIDENTIFIED MALE: So you were on the first floor when this happened? You heard it from coming -- coming from either the second floor or third floor then? LISA BOTTLE: Yes, it was coming from either the second floor or third floor, because they shot down. (voice-over): So they shot from the upper floors down to the lower floors then? BOTTLE: Well, they did both, because I only saw a couple of shots come down through. But, yes, they did shoot down. UNIDENTIFIED FEMALE: Did you see any victims taken away? Did you -- did you see any victims? BOTTLE: I did. I don't know what's happened to them. I don't know what's all going on -- what's all kind of happened. But, yes, I did see them shoot down and hit someone. UNIDENTIFIED MALE: Was it one person or several people? Do you know exactly how many people may have been in there? BOTTLE: I don't know and I'm not sure enough to know, due to how many shots were fired, how -- if it was one or two people or if it was more than one. But I didn't see anybody. I just saw -- because I was on first floor and they were on the higher floors, I'm guessing second. UNIDENTIFIED FEMALE: Did you happen to see the shooter or a shooter? BOTTLE: I did not. No. UNIDENTIFIED FEMALE: OK. BOTTLE: We hit the dirt. We hit pavement as soon as possible. UNIDENTIFIED MALE: What was your response? Obviously, that's the last thing you would expect to happen when you are working at the mall, doing your normal job. What was your response? What did you do once that -- once the (INAUDIBLE)? BLITZER: All right, we're going to break away from our affiliate coverage to go to a live news conference with details on what happened at that shopping mall. Let's listen in to the Omaha Police Department. SGT. TERESA NEGRON, OMAHA POLICE: ...that had been injured by gunshot. They also -- other officers arrived and they began to clear the mall, searching for a suspect. They located other victims. At this point, we can tell you that we have confirmed nine people that have been -- that have died from their injuries. We have five other people that have suffered injuries, have been transported to the area hospitals, Creighton University Medical Center and the Nebraska Medical Center with injuries. We have been able to clear the mall. We do not believe that we have any other shooter. The person we believe to be the shooter has died of a self-inflicted gunshot wound. The people are still inside the mall at this point in time. We can tell you that we've also set up a location for concerned family at the Hampton Inn. There will be no media allowed at that location at this time. Right now, we are still conducting our investigation and do not anticipate the Westroads Mall being open possibly until tomorrow. I can tell you that both Mayor Fahey and Chief Thomas Warren are out of town at this point in time. They have been notified and provided the details and they are on their way back to Omaha at this point. QUESTION: Teresa, could you just describe the shooter, just sort of male, female, age? NEGRON: We believe the shooter to be a male. I don't have very many details regarding the age or description at this point in time. When we first arrived, I'm sure most of you that were listening to the radio could hear varying descriptions that were put out. I can't confirm exactly what that description is. But I can tell you it's a male. QUESTION: Does the nine include the shooter, the nine dead? NEGRON: No, it does not. NEGRON: I'm sorry, it does. UNIDENTIFIED MALE: The nine does include a shooter. UNIDENTIFIED FEMALE: Oh, it does. QUESTION: He took his life inside the mall? NEGRON: Yes, that's what we believe to have occurred. UNIDENTIFIED FEMALE: Can you tell us who the eight victims were and where all they were found? NEGRON: I can tell you that it appears at this point that most of our victims were inside Von Maur. QUESTION: Were they on the outside of Von Maur? NEGRON: They were inside the store. QUESTION: Were there any outside? NEGRON: Not that I'm aware of at this point. QUESTION: Were they on the first floor and the third floor? Were they in (INAUDIBLE)? NEGRON: Well, we had several that were on the third and on the second floor of Von Maur. QUESTION: Any indication of motive, Teresa? NEGRON: At this point, I can't really answer that question and we're still investigating this to try to determine exactly why this all occurred. QUESTION: Are there still people hiding inside the mall, still terrified of what happened? NEGRON: I can tell you, we've secured and cleared most of the mall. There are some -- a few areas that we're still clearing. But, as far as we know, there is no other shooter that's in this mall. UNIDENTIFIED MALE: And we don't believe any customers are hiding or in fear right now. We're just simply processing individuals to identify them and then we're releasing them if they were not witnesses. QUESTION: Do you... QUESTION: Or customers? NEGRON: I'm sorry. QUESTION: Do you know the dead versus store employees and customers? NEGRON: You know, at this point, we don't have that information. QUESTION: Do you know if any employees were killed? NEGRON: Again, we have not identified the people that are deceased at this point. QUESTION: Do you know at all what -- if they're from Omaha or Nebraska? NEGRON: Again, we haven't identified any of the deceased at this point. QUESTION: What kind of gun did the shooter have? NEGRON: At this point, we believe it was a rifle. QUESTION: Is six minutes an appropriate response time when there's an active shooter at the mall? NEGRON: We -- an active shooter at the mall? We sent every available officer in the City of Omaha. They came to the mall in lights and sirens. Six minutes is the time that it took them to arrive here at the scene. QUESTION: What about security at the mall? QUESTION: Do you know if the shooter is any way -- knew any of the other eight people? NEGRON: No, I don't have that information right now. QUESTION: Was there only one gun? NEGRON: As far as we know, at this point, that's that. QUESTION: On the other side of Von Maur, there is a secured area where there's been some police tape put up. The officers have been interested in some vehicles inside that tape. Do you know what they're looking at there? NEGRON: Well, it's very possible that we are, at this point, there -- the person that we believe to be the shooter came to the mall in a vehicle, so we would be looking for that. QUESTION: Can you tell us where it started and where it proceeded from there? NEGRON: I'/m sorry. QUESTION: You said nine were confirmed dead. Do you know how many injured overall? NEGRON: There's a total of 14 people that were injured. Nine of those people are deceased at this time. QUESTION: What's the status of the other five? Are they -- they're at the medical center -- are they in critical condition? What are they -- are they... NEGRON: To my knowledge, we have two people that are still in critical condition and three that are -- have gunshot wounds. QUESTION: Can you tell us where the shooting started and then where it proceeded from there? NEGRON: You know, we are still doing that investigation and it is way too early for us to provide those types of details. QUESTION: Any children among the injured or dead? NEGRON: I don't have that information at this time. QUESTION: Was the shooter alive when officers arrived? NEGRON: You know, that's very difficult to tell. I don't know. I can tell you that the shooter is deceased and it appears to be a self- inflicted gunshot wound. QUESTION: Did the shooter say anything when he went in? NEGRON: I don't have that information at this time. QUESTION: ...the initial officer on the scene, did the responding officers hear anymore gunshots when they (INAUDIBLE)? NEGRON: To my knowledge, there was no other gunshots that were heard upon arrival. I believe that when the person who called 9/11 made that call, there was a possibility that there were gunshots heard in the background. QUESTION: Has anyone else told you how this began or what -- how -- what's -- did they say anything or did he just sort of (INAUDIBLE)? NEGRON: You know, at this point, I don't have any information as to what this person said when they came in the mall or if they said anything. We just don't have that information right now. BLITZER: All right, we're going to break away from this news conference. Clearly, lots of questions and not a whole lot of answers. But Sergeant Teresa Negron of the Omaha Police Department has told us now that nine people are dead. That would include the shooter who supposedly -- allegedly -- took his own life, had a rifle there. Five other people are injured, two of them critical, three others with gunshot wounds. Unclear how serious those wounds are. But the incident, apparently, is over. Police are now going through this shopping mall in Omaha, Nebraska, clearing it, making sure that people leave. But this is a horrific incident that unfolded over the past couple hours right in Omaha, Nebraska. Nine people, including the shooter, dead. We'll stay on top of this story and bring you more information as it comes in. In the meantime, let's check back with Jack Cafferty. He's got The Cafferty File. The White House quickly reacting, Jack... CAFFERTY: They did, yes. BLITZER: ...to your e-mail question... CAFFERTY: I have a statement from the... BLITZER: ...of the last hour. CAFFERTY: I have a statement here, Wolf, from the White House concerning the Citizens for Responsibility and Ethics in Washington, which is a private citizen government watchdog group that asserts that there are 10 million missing White House e-mails. The acronym for that group is CREW. The statement is as follows: "CREW has yet to provide any basis for their assertion, be it their original assertion -- five million e-mails -- or their new claim. We are aware that some e-mails may not have been automatically archived in the past, but they may be available on backup tapes. Unlike what the liberal group CREW has asserted, we have never been without a backup system. The Office of Administration at the White House has been maintaining and preserving backup tapes for the official e-mail system." Now, on to other things. You remember those heady days when home prices were rising like the tech stocks did back in the late 1990s? The housing market was on fire. Subprime mortgage loans, rapidly rising housing prices -- well, that was a combination simply too to pass up for a lot of people. The trouble is, those things never last. And when that bubble burst, the hangover from the real estate party is turning out to be much worse than anyone expected. Real estate foreclosures have now risen to the point that they are threatening the overall economy. People who were enticed into buying more house than they could afford because of very low teaser mortgage rates are now seeing those mortgage payments rise when the loans are being adjusted upward. And a lot of people simply can't afford the higher house payments and they're losing their homes. Enter the federal government. President Bush is expected to outline a plan tomorrow to freeze mortgage rates for five years for many U.S. homeowners who are facing these sharp increases in their monthly payments. Officials say the plan could help prevent up to a half a million borrowers from possibly losing their home this next year. The program will be aimed at borrowers who can afford their existing rates and who are current on their payments, but could -- who possibly could face default when their mortgage resets at a higher interest rate next year. So the question we're posing this hour is this -- should the federal government bail out homeowners who are facing foreclosure because of rising interest rates? E-mail your thoughts to email@example.com or go to CNN.com/caffertyfile -- Wolf. BLITZER: Jack, thanks very much. Coming up, criticism for the Democratic presidential frontrunner, Hillary Clinton, from one of her rivals. (BEGIN VIDEO CLIP) GOV. BILL RICHARDSON (D), PRESIDENTIAL CANDIDATE: Well, she is qualified. But she made a mistake in voting for that resolution. That was saber rattling. (END VIDEO CLIP) BLITZER: Democratic presidential candidate Bill Richardson joining us in THE SITUATION ROOM. You're going to find out what else he has to say about Hillary Clinton and a lot more. Also, Washington State now reeling from the worst flooding in decades. Hundreds of people are rescued from their homes. We'll take you there live. Plus, a danger in the sky that passengers can't see -- find out why insiders say it's only getting worse. Stay with us. You're in THE SITUATION ROOM. BLITZER: We just want to update you on the breaking news that we've been following the past couple of hours. It's now over, that incident at a shopping mall in Omaha, Nebraska . Police -- Omaha police telling us just a little while ago, nine people, including the shooter, dead. The shooter apparently killing himself with a rifle. Five other individuals -- presumably either shoppers or employees at that mall -- injured, two of them in critical condition, three others suffering from gunshot wounds. But the incident, apparently -- apparently, is over. Sergeant Teresa Negron of the Omaha Police Department having no information -- no speculation on what, if any, justification or rationale there may be for this incident. But the incident is over in Omaha, Nebraska. President Bush is stepping up pressure on Iran despite new intelligence contradicting his earlier statements about the country's nuclear weapons program. He's warning President Mahmoud Ahmadinejad to "come clean" and Mr. Bush is seeking new sanctions against Iran. CNN's White House correspondent, Ed Henry, is standing by. He's joining us. What else did the president have to say -- Ed? ED HENRY, CNN CONGRESSIONAL CORRESPONDENT: Well, Wolf, the president made clear that he believes this new National Intelligence Estimate is no vindication for Iran and he's also sticking with his contention that, in fact, Tehran is still a threat. HENRY (voice-over): President Bush laughed when asked about a demand for an apology from irregular president, Mahmoud Ahmadinejad. Then, after the TV cameras were off, the president told reporters: "You can mark down I chuckled." Earlier in the day, he was equally as defiant. GEORGE BUSH, PRESIDENT OF THE UNITED STATES: The Iranian nuclear issue is a problem and continues to be a problem that must be addressed by the international community. HENRY: At a quick stop in Nebraska, the president was supposed to focus on health care and raising political cash for Republicans. But when he landed in Omaha, Mr. Bush brought up Iran -- a clear sign the White House realizes the president's Tuesday press conference did not do enough to stem the tide of negative publicity from the National Intelligence Estimate, reviewing that, contrary to public statements by the president and Vice President Cheney, Iran suspended its nuclear weapons program four years ago. BUSH: The Iranians have a strategic choice to make. They can come clean with the international community about the scope of their nuclear activities or they can continue on a path of isolation. HENRY: The president is focusing on the part of the report which found Iran did, at one point, have an active nuclear weapons program that could be restarted. That's why White House officials say they're moving full speed ahead on seeking a new round of United Nations sanctions against Iran and have gotten positive feedback from key allies in France, Germany and Great Britain. BUSH: The Iranian government has more to explain about its nuclear intentions and past actions -- especially the covert nuclear weapons program pursued until the fall of 2003. (END VIDEO TAPE) HENRY: but another round of tough sanctions was already going to be an uphill battle, even before this new intelligence emerged. Now it's going to be even tougher to get China and Russia on board-- Wolf. BLITZER: Ed Henry, stand by. Thanks very much for that. In Iraq, meanwhile, a car bomb killed at least 15 people on a busy shopping street in Baghdad, just as the defense secretary, Robert Gates, was visiting another part of the city. And those who know the situation there say the overall violence is intertwined with the tense relationship between the United States and Iran. And joining us, now, from Baghdad, our correspondent Michael Ware. We know this National Intelligence Estimate now saying that the Iranians actually stopped building a nuclear bomb back in 2004. But what about these conflicting reports that we're getting about Iran still meddling in Iraq? What's going on? MICHAEL WARE, CNN CORRESPONDENT: Well, Wolf, what I can tell you is the latest that the U.S. military intelligence is telling Secretary of Defense Robert Gates on his sixth visit here to Iraq. What they're saying is that the number of attacks that they can directly link to Iranian support is down. Whether they can attribute that to a downturn in Iranian influence, that they cannot answer. The other thing I can tell you, Iranian nuclear issues and Iranian issues on attacks on America here in Iraq are not unrelated. Now, during the historic talks between the Iranian ambassador here in Iraq and the American ambassador, Ryan Crocker, here in Iraq, it was made very clear they would only talk Iraq. They would not talk nuclear issues or anything else. Iran's strategy has been forced to -- has been to force to America to bleed here in Iraq to gain concessions elsewhere. Indeed, we got to a point where top American commanders were saying just a few months ago, more American troops were dying as a result of Iranian- backed violence than Al Qaeda-backed violence. We've now seen that dip. But right now, I can tell you, Secretary Gates is being told that Iran, according to U.S. military intelligence, is still training Iraqis to kill Americans. None of this, Wolf, is unrelated. BLITZER: Robert Gates -- he's in Baghdad right now -- an unannounced visit. And he and others are suggesting things clearly are getting better. Is security and stability in Iraq right now within reach? WARE: The short answer is that, yes, things are better. Where we would have 1,500 or 1,600 attacks a week -- be it bombs or shootings or suicide detonations or whatever you want -- it's down to something like 500 on a week. Can you imagine if there was 500 and something attacks in Pakistan or Israel or America? Yet this is our idea of success now. That's how numbed we've become to the violence. Nonetheless, less Americans, less Iraqis are dying. There's two reasons for that. One, America is backing Sunni militias. They're protecting their areas. America has finally cut a deal with the insurgency. Secondly, Iran has cut down its military activity. You talk to the top U.S. officials, they don't yet know why. They don't believe it will old. But there's a key question there. It's quite a dilemma -- Wolf. BLITZER: Michael Ware, our reporter in Baghdad. WARE: Thank you, Wolf. It's a pleasure. BLITZER: All right, we're going to take a quick break. When we come back, we'll have the new reports coming in on the fatalities in that Omaha mall shooting. Police now confirming nine people are dead. The gunman, an apparent suicide, as well. We're going to have the latest for you from Omaha. Also, the U.S. Supreme Court case that could determine the future of hundreds of suspected terrorists. And a warning that could impact everyone who flies about a looming danger in the sky. Stay with us. You're in THE SITUATION ROOM. BLITZER: to our viewers, you're in THE SITUATION ROOM. Happening now, at least nine people are dead, including the gunman, after a shooting rampage at a mall in Omaha, Nebraska. Five other people are wounded, two of them critically. Police say the gunman shot himself. The shooting happened earlier this afternoon at Omaha's popular Westroads Mall. We'll update you with more information. Republican presidential candidate Mike Huckabee is facing new criticism about a past incident that has to do with a convicted rapist who was released while Huckabee was Arkansas's governor. The man, Wayne Dumond, went on to rape again and to commit murder. Huckabee's Republican rival, Mitt Romney, is trying to clean up a mess in his own backyard. He's fired his landscaping company for employing illegal immigrants. Questions are now being raised about whether that will undercut Romney's credibility on the immigration issue. I'm Wolf Blitzer. You're in THE SITUATION ROOM. It's a critical Supreme Court case that could determine the fate of hundreds of suspected terrorists and foreign fighters held at the U.S. naval base in Guantanamo Bay in Supreme Court. At issue -- what rights, if any, do they have to contest their imprisonment? Our senior Pentagon correspondent, Jamie McIntyre, has been following this story for us -- Jamie, what happened at the Supreme Court today? JAMIE MCINTYRE, CNN SENIOR PENTAGON CORRESPONDENT: Well, Wolf, I can tell you, after sitting in on a little more than an hour of an hour of arguments, I can tell you, the Supreme Court is taking quite seriously this allegation that prisoners in Guantanamo should have their day in court. MCINTYRE (voice-over): Outside the court, snow fell on two dozen demonstrators portraying the plight of prisoners at Guantanamo -- held indefinitely without the ability to confront their accusers, see evidence against them, have legal representation or challenge their detention in federal court. Inside the court, Justice Stephen Breyer posed a question that closely mirrored the circumstances of Lukdar Bumedian (ph), an Algerian arrested in Bosnia in 2001, who was one of the two named plaintiffs in the case. STEPHEN BREYER, SUPREME COURT JUSTICE: I am from Bosnia and I've been here six years and the Constitution of the United States does not give anyone the right to hold me six years in Guantanamo without either charging me or releasing me. So, I'm asking you, where can you make that argument? PAUL CLEMENT, U.S. SOLICITOR GENERAL: I'm not sure that he can make that argument, Justice Breyer. MCINTYRE: But Justice Antonin Scalia carried the flag for the Bush administration challenging lawyers for the detainees to cite a single case in which captured foreigners held overseas were granted the habeas corpus right to challenge their detention. ANTONIN SCALIA, SUPREME COURT JUSTICE: Counsel, we had 400,000, 400,000 German prisoners in this country during World War II. 400,000 of these people. It never occurred to them. MCINTYRE: But in World War II, the detainees were prisoners of war, while P.O.W. status has been denied to Guantanamo suspects who don't fight for any nation or traditional army. The government insists opening the federal courts to enemy combatants would be unprecedented and make holding dangerous terrorists impossible. Ultimately, the case could hinge on whether Guantanamo is, for all intents and purposes, U.S. territory as the detainees' attorney argued. SETH WAXMAN, GUANTANAMO DETAINEES ATTORNEY: I didn't mean to be facetious when I said our national control over Guantanamo is greater than it is over in a place in Kentucky. MCINTYRE: So the more than 300 detainees in Guantanamo, some of them there almost six years, could have to wait another six months to learn their fate. Wolf, the high court is expected to hand down a decision by late June. BLITZER: With enormous ramifications, indeed, Jamie, thanks very much. As Jamie just mentioned, the case right now before the Supreme Court could hinge on whether Guantanamo is actually U.S. soil. Back in 1903, the U.S. government leased 45 square miles of water and land at Guantanamo Bay for use as a U.S. naval base. In 1934, a treaty between the U.S. and Cuba made the lease permanent. It could only be canceled if both countries agree. The U.S. pays $4,000 a year in rent, but Fidel Castro has never cashed the checks because he considers the lease illegal. In 1964, Castro cut off water to the base, so every since then, the U.S. has had to supply its own water, its own power and making gitmo, as it's called, entirely self- sufficient. From the national intelligence estimate on Iran's nuclear activities to what to do with those detainees at Guantanamo Bay in Cuba; talking points are coming fast and furious this week in the presidential race. And joining us now, the governor of New Mexico, the democratic presidential candidate, Bill Richardson. Governor, welcome back. GOV. BILL RICHARDSON (D), PRESIDENTIAL CANDIDATE: Thank you, Wolf. BLITZER: Let's talk about Iran, this new national intelligence estimate. Arguably the democratic presidential front-runner Hillary Clinton says that she voted in favor of that resolution that would declare the Iranian revolutionary guard a terrorist organization. Some saying she effectively gave the president a green light to go ahead and launch military strikes against Iran. Now, we know that four years ago the Iranians stopped developing a nuclear bomb. Is she qualified to be commander in chief? RICHARDSON: Well, she is qualified but she made a mistake in voting for that resolution. That was saber rattling, that resolution was not necessary at a time when I think diplomacy should be paramount. BLITZER: She doesn't think she made a mistake. She points that 70 other senators vote in favor of that resolution. RICHARDSON: I think they all made a mistake. I think this report of the NIE basically says that Iraq is put on hold. BLITZER: You mean Iran? RICHARDSON: Iran. They're still enriching uranium. It's not exactly something we should celebrate. Now, at the same time ... BLITZER: But they are entitled to enrich uranium under the nuclear non proliferation to be provided it is for peaceful purposes. RICHARDSON: They are and I see this report. You know, I'm an optimist. I see this as good news. I think this provides an opportunity for a diplomatic opening. I can tell you as a former U.N. ambassador it's going to be hard now in the U.N. security counsel with China and with Russia to get sanctions. BLITZER: Because U.S. credibility ... RICHARDSON: That's right. Our credibility is shot. What this argues for, in my judgment, is direct talks without preconditions, United States and Iran to talk about them stopping. BLITZER: You want President Bush to meet with Ahmadinejad? RICHARDSON: Well, I would do a little preparatory work, first. I don't think Ahmadinejad is terribly stable. I would talk to moderate clerics. I would start at a lower level, secretaries of state, foreign minister. I think there are moderate elements there. And I think what we have, Wolf, is the possibility of an energy deal. You know in exchange for Iran developing nuclear power, with an assured fuel cycle, supervised outside of Iran. You know, perhaps that this could ... BLITZER: You think there is an opening. Let's move on to talk about another issue on the agenda today. The U.S. Supreme Court hearing this case about the Guantanamo Bay enemy combatants, the detainees, that they should get some more legal rights right now. As a practical matter, I know you're opposed to what's going on at Guantanamo Bay. Would you as a governor of New Mexico be willing to take these 300 detainees into your state and let the law deal with them there? RICHARDSON: Well, I think, yes, I think any governor should. Military court should take care of this. I always felt Guantanamo, our detainee policy has been wrong. It deprives due process. It's sustained internationally. Yeah, I think it makes sense to take them into civilian courts, take them into military courts. BLITZER: You have another proposal to withdraw all U.S. forces from Iraq within a year, if you were elected president. You know, I asked Michael Ware, our correspondent in Baghdad earlier today, he's been there for four years plus. What would happen? How would he feel if all U.S. troops were out of Iraq? I want to play his answer. Listen to what he told me. (BEGIN VIDEO CLIP) MICHAEL WARE, CNN CORRESPONDENT: I don't feel safe now, but I can tell you what, if every American soldier left, then it would be much more chaotic. I'd be dodging a lot more bullets and I'd be dodging a lot more kidnaps and I'd be treading much closer to the wire. What we're looking at is a much more destabilized Iraq. No matter what you can do in the next 18 to 24 months, we're looking at a more destabilized region. (END VIDEO CLIP) BLITZER: I wonder if you want to comment because he paints a very gloomy picture if what happened was your proposal was enacted. RICHARDSON: Well, I totally disagree with his assessment. Here's my view, Wolf. You can't start a peace, in other words a political compromise among the three groups in Iraq; a U.N. peacekeeping force that is going to be needed, a donor conference to rebuild Iraq unless we get all our troops out within year. It's already chaos there. It's already civilian conflict and it's already a civil war. What makes sense in my judgment is to have the leverage of our withdrawals within a year in a safe way. I'd ask our military experts, and by the way, there are a number of generals, three-star generals that agree with me that we can have the safe withdrawal but use that to convince the Maliki government, which right now believes we're going to stay forever. Why should they give up power to move towards a political compromise? Maybe a soft partition. Sharing ... BLITZER: You're not backing down. You still think get them all out, 160,000 within a year. RICHARDSON: Absolutely and get all the contractors out. BLITZER: One final question. The question I asked you at that last debate in Las Vegas when you suggested that human rights was a greater priority for the U.S., for U.S. president than national security and I wonder if you've had a chance to think about that and if you still believe that. RICHARDSON: Well no, you asked me that in the context of the Pakistani situation. I think you to be very clear that American values, respect for democracy and the Geneva convention, human rights, that has to be part of any occasion in balancing America's security needs. I think in the case of Pakistan, yeah I do believe that we should have made it very clear to the Pakistanis that we expected them to respect democracy, for Musharraf not to cancel elections, not to have an emergency order. Look, Wolf, our strength is military. Our strength is political and but our greatest strength is moral authority and we've lost that authority by not emphasizing human rights and democracy. We should be the world's conscious and not the world's policeman. BLITZER: Governor, thanks very much for coming in. RICHARDSON: Thanks, Wolf. Thank you. BLITZER: Deadly flooding. Washington and Oregon are in states of emergency right now. We're going to take you to the flood zone live. Plus, my interview with presidential candidate Mike Huckabee. He's fighting efforts to tie into a parolee who went on to kill. Stay with us. You're in THE SITUATION ROOM. BLITZER: Want to update you on that shooting incident in a shopping mall in Omaha, Nebraska. Police now saying nine people dead, including the shooter. Five others injured, two of them critically. Joining us now on the phone is a witness to what happened over in Omaha. Todd Trimpe is joining us. Todd, tell us where you were and what you saw. TODD TRIMPE, WITNESS AT MALL: Well, I was in the area for business and I had just been right in the area right after the incident. A good majority of the police officers were showing up at the same time and I had pulled into the parking lot because about two weeks ago, somebody had left a grenade in the parking lot. I thought it was something about that scale. There was going to be a bunch of people around and wondering what was going on at the other end of the parking lot. You could immediately tell this was different because there was a police presence throughout the whole mall, the whole parking lot. BLITZER: Did you have a sense immediately, Todd, how significant this shooting incident was? Eight people shot by this shooter who apparently then took his own life. TRIMPE: Yes. I was speaking with the car next to me and they had mentioned that they thought there were gunshots but they didn't know how many people and they didn't know anyone was hit at all. At that time there was a lot of speculation going about. But with the amount of police officers there, you could definitely tell that this was no average thing, like we would normally see around here. BLITZER: Todd, thanks very much for joining us, appreciate it. Once again, we have no clue why this guy went into this shopping mall, started killing people, eight people dead. He then killed himself. Five others he shot, two of them now in critical condition, unclear the condition of the three others suffering from gunshot wounds. He had a rifle in that shopping mall. What a nightmare. The Pacific Northwest is waiting for waters to recede to see what's left from storms that caused major flooding. Much of the region now under a state of emergency. Several people there are dead and thousands of others have no power. In Washington State alone some 300 people have been rescued so far. CNN's Thelma Gutierrez is on the scene for us in Washington State. So, what's the latest, Thelma? How is this situation unfolding? THELMA GUTIERREZ, CNN CORRESPONDENT: Wolf, I can tell you things are getting a little bit better at least as far as the weather is concerned. The sun is peeking out and the forecasters say that the weather is expected to be dry through the weekend and in neighborhoods like this, if you take a look behind me where they have experienced two landslides in this one area alone. Residents are saying this is exactly the break that they've needed. GUTIERREZ: This is what residents in western Washington woke up to. Digging out of the mud, a massive clean up effort. This is Barbara Bull's driveway in Washington. Her neighbor's yard came crashing down on her driveway forcing her brand-new car into the living room. She was on the phone at the time. BARBARA BULL, RESIDENT: We talked only about a minute and a half when this huge explosion was and I said, oh, Jack, I said there's a bomb in my house. Hang on and I went to my window and here's my car sticking in the door and I ran back and I said, please call 911. GUTIERREZ: Further south in Lewis County, the damage was devastating. Towns looked like islands and streets, rivers. UNIDENTIFIED MALE: And I have never in my whole life seen the water come up this high. GUTIERREZ: The Coast Guard and National Guard airlifted residents to safety. GOV. CHRIS GREGOIRE, WASHINGTON: The largest aerial search and rescue operation is ongoing and it's the largest in a decade. GUTIERREZ: Landslides interrupted Amtrak service and on I-5, the main corridor between Portland and Seattle, a 20-mile stretch of highway was under ten feet of water. GREGOIRE: We have got an economy that is suffering mightily because of the shut down of the freeway. GUTIERREZ: 20 major roads are still closed in this area and 50,000 people are without utilities. Wolf, back it you. BLITZER: Thelma, thank you. Good luck to all the folks out there. Our viewers sending in new pictures from the massive flooding in the Midwest. Let's go to our Internet reporter Abbi Tatton. She has some of them. What are you seeing, Abbi? ABBI TATTON, CNN INTERNET REPORTER: Wolf, images from viewers that are stranded in their homes have been sent in to CNN's I-report. Take a look at this. Imagine cleaning up after this. This is Centralia, Washington where John and Tori Quillen live. This is their neighborhood there. They said yesterday they saw the water rushing up like a river past their house and they said it was brown and mercury and I just spoke to John who is now trying to clear up. He says the water has receded such that he could make it out to his car. That's his VW Beetle right there. But he said they got off lightly compared to people down the road. Look at the rescue efforts under way. Tessa Buswell sends these pictures in a father, a high schoolteacher who was helping people out rescuing people from a shopping center. Send the pictures into CNN.com/ireport. Wolf. BLITZER: Abbi, thanks very much. Turning now to air travel and its risks, sometimes those risks are scary before you even get off the ground. UNIDENTIFIED MALE: Stop, stop, stop. BLITZER: That's the sound of an aircraft controller narrowly averting a collision on the runway over in Ft. Lauderdale, Florida in July. Congressional investigators say several factors could lead to a catastrophic runway collision here in the United States. The Government Accountability Office today issued a report citing those factors and among them are operational difficulties with newly installed runway safety technology, failure by the Federal Aviation Administration to revise the national runway safety plan since 2002 and air traffic controller fatigue. Lots of problems out there. Air traffic controllers say the Federal Aviation Administration is cutting costs in ways they say would cost lives. Are you at greater risk when you fly? The FAA would not agree to give us an on camera interview for this story but it does say we're in the safest period in aviation history. Here's CNN's Susan Roesgen. SUSAN ROESGEN, CNN CORRESPONDENT: Passengers on a plane flying towards Chicago recently never knew they had been seconds away from a disaster. On November 14, an air traffic controller at a busy regional control center made a mistake sending a Midwest Airlines jet into the path of a United Express jet. But on the Midwest jet, the computer alert system in the cockpit warned the pilots, stopping a possible mid air collision. BOB RICHARDS, FORMER AIR TRAFFIC CONTROLLER: It said pull up, pull up and of course the aircraft pulled up just before we could go to the altitude of the other aircraft. ROESGEN: Bob Richards spent 22 years as an air traffic controller at Chicago's O'Hare Airport before he retired this year and he's come out with a book called, "Secrets from the Tower," his account of why air traffic controllers are fed up. RICHARDS: Controllers have nothing to gain at this point but retirement. ROESGEN: A record number of air traffic controllers, 828, retired last year. To fill the gap, some air traffic controllers at the busiest airports like O'Hare are working longer shifts and six day weeks. Bryon Zilonis is a leader for the Air Traffic Controllers' Union in the Great Lakes area. He says it takes years to train new controllers who can handle the high demands of the job. BRYON ZILONIS, CONTROLLERS UNION: An air traffic controller is not hired on day one. It took me five years to become an air traffic controller from the day I walked into the control room to the day I became a full performance double controller. It was about 18 months before I was even allowed to talk to an airplane. ROESGEN: The union says fewer controllers means potentially more close calls in the air and they say fewer eyes on the sky adds to the growing number of flight delays. The Federal Aviation Administration told CNN in emails that control tower staffing varies but that staffing today is determined by actual traffic and need. The FAA also says that 1800 new controllers were hired last year but only 40 are fully trained and actually working full time. Bob Richards says that's not enough controllers and it's only going to get worse with all the retirements. RICHARDS: They don't need that stress anymore. They've had enough. ROESGEN: And when they leave, the fear is they'll leave too many planes flying too close for comfort. ROESGEN: The air traffic controllers are pushing for a new bill in Congress that could force the FAA to negotiate a new contract with them, one that they say would give them better pay and better hours. Susan Roesgen, CNN, Chicago. BLITZER: A Philadelphia couple is accused of living the high life on someone else's dime. Coming up, there's a book connection to this modern day Bonnie and Clyde story. Later, presidential hopeful Mike Huckabee fighting to send off connections between him and a killer. Stick around. You're in THE SITUATION ROOM. BLITZER: A young couple is facing more charges today after turning themselves into the police, Philadelphia police department. CNN's Carol Costello is here in THE SITUATION ROOM. All right. So what happened? How did they pull this off? CAROL COSTELLO, CNN CORRESPONDENT: It's an amazing story, Wolf. I mean this a couple who had it all, glamorous good looks, great education, supportive parents and now they're dubbed the new Bonnie and Clyde. Police say they found fake licenses, credit cards and thousands of dollars in their posh apartment and this very interesting book. COSTELLO: Dubbed the modern day Bonnie and Clyde, they've become infamous for, well being well versed in the art of cheating. Philadelphia police say Jocelyn Kirsch and her boyfriend Edward Anderton stole their neighbor's identities living the life of luxury, traveling the world on their neighbor's credit cards and tucked away in their $3,000 a month condo was this book by Jessica Dorfman Jones, "The Art of Cheating," a nasty little book for tricky little schemers and their hapless victims. JESSICA DORFMAN JONES, AUTHOR, "THE ART OF CHEATING": Either they were the biggest boneheads who have ever lived and they thought that they could find a criminal manifesto in the humor section or they just thought that it was funny. COSTELLO: Jones' book, "The Art of Cheating," is a parody, a joke aimed at people who crave self help books with chapters like falsifying insurance claims. The good news about insurance fraud she writes is that you can get away with it or sleeping your way to the top, how to work less, achieve more. But these sediments seem to be what Kirsch and Anderton lived by. They alleged bilked their neighbors out of $100,000 despite educations that could get them high paying jobs. DR. GAIL SALTZ, PSYCHIATRIST: I mean just to buy a book like this is just a bit of a wink, wink, ha, ha, isn't this funny for us, nobody knows and you know we're living it up. COSTELLO: Imagine them reading chapter three in Jones' book, forging handwriting. It says, "You can decide how much you want to make, what kind of patsy you want to target and how much time you'll spend doing it. Your days are your own, and you're your own boss." It's a paragraph that perfectly parodies a sense of entitlement and psychiatrist Dr. Gail Saltz says it most likely describes what apparently motivated Kirsch and Anderton. SALTZ: The American dream was supposed to be you know if you worked really hard, you could achieve something. Now the American dream is sort of you can have fame and fortune and the question of whether you really have to work hard for it enough is up for debate. COSTELLO: Now the author once again Ms. Jones told me this is not a how to book. It's a joke. BLITZER: A joke, all right. Thanks very much, Carol Costello, with that story, an interesting story indeed. I want to apologize for a typographic error we had earlier in THE SITUATION ROOM dealing with the breaking news we were following out of Omaha, Nebraska. We inadvertently typed Obama, Nebraska and that was obviously a mistake. We apologize for that. Let's go to Jack Cafferty. He's got the Cafferty File. Jack. JACK CAFFERTY, CNN CORRESPONDENT: All right, Wolf. The question this hour, President Bush is actually going to lay out the details of this tomorrow. Should the federal government bail out homeowners who are facing foreclosure because of rising interest rates? Ed writes from Berlin, New Jersey, "I guess I'm old fashioned. I bought a home, had a mortgage; first thing I did was get a second job. I had only one TV, no luxuries. These new guys bought a bigger home than they needed, sports cars, wined and dines, and now want help. Nobody helped me and nobody should help them either." Edward in Maryland writes, "I see no problem bailing out homeowners who actually live in their homes and face foreclosure. We should not bail out investors who were buying the homes for resale or to flip them." Karen writes, "Yes, the government should help bail out exorbitant variable interest rates! It would be the first thing that this administration has done for the working middle class in the last six years!" Todd in Connecticut, "The government should not bail out homeowners who took adjustable rate mortgages. You have to know what you're buying before you but it. But, if the government is going to help them out, I have some private student loans that are crippling my bank account. Can Mr. Bush help out with that?" TO ORDER A VIDEO OF THIS TRANSCRIPT, PLEASE CALL 800-CNN-NEWS OR USE OUR SECURE ONLINE ORDER FORM LOCATED AT www.voxant.com
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Stainless steel bars mainly include stainless steel black bars; bright bars; grinding bars; square bars; hexagonal bars; special-shaped bars; free-cutting bars, etc. ●The Stainless Steel Bar price is moderate: We export a large number of 303 stainless steel round bars and super duplex bars for a long time, so we signed a long-term cooperation contract with the stainless steel bar manufacturer which provided us with the most competitive price. If you happen to want to buy stainless steel bars, please contact me as soon as possible. We have professional QC, they will go to the factory to inspect the product quality. Generally, after the customer places an order, our QC staff will go to the factory to track the production of the product. Once a product quality problem is found, we will propose improvements, take out the poor quality products, and re-produce. Although we cannot guarantee that the stainless steel bar price is lower than others, we must ensure that the quality of our ss bars for sale is higher than that of other factories while controlling ss bar costs. What is the stainless bar? Stainless steel bar is a simple cross-section profile, generally delivered in straight strips. According to the cross-sectional shape, the types of bars are divided into round, square, hexagonal, and architectural threaded steel bars. Stainless steel rod forming methods are mainly divided into continuous casting, hot rolling, forged stainless steel rods, and cold drawing. Nowadays, there are many continuous casting and rolling. Single continuous casting is generally used for pipe making, and most of the machining methods are hot rolling, Forged and cold drawn. The latter is a periodic cross-section profile, sometimes called a ribbed steel bar. The most important cross-sectional shape of the bar is still around. It is generally believed in foreign countries that the cross-sectional diameter of the bar is Φ9~300mm. In domestic production, it is recognized by convention that the product range of the bar workshop is Φ10~50mm in cross-section. How to bend stainless steel bars? Due to the needs of users, we may need to bend the stainless steel bar before it can be used. We usually buy a bending machine. If the bending machine is not available or cannot be used, we need to use an oxygen-acetylene torch to add stainless steel bars, and then heat the area that needs to be bent. Polish stainless steel bar The stainless steel bars we export are processed by professional technicians. We will polish any stainless steel bars. Also, provide you with quality service. We can also cut your steel bars to a certain size, grind off the rough edges, and then weld or process the materials to assist your manufacturing process. CMPI is good at custom and unique work, so please contact us immediately and let me tell you how to choose stainless steel bars!
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Here we report the genome sequence of the honeybee Apis mellifera, a key model for social behaviour and essential to global ecology through pollination. Compared with other sequenced insect genomes, the A. mellifera genome has high A+T and CpG contents, lacks major transposon families, evolves more slowly, and is more similar to vertebrates for circadian rhythm, RNA interference and DNA methylation genes, among others. Furthermore, A. mellifera has fewer genes for innate immunity, detoxification enzymes, cuticle-forming proteins and gustatory receptors, more genes for odorant receptors, and novel genes for nectar and pollen utilization, consistent with its ecology and social organization. Compared to Drosophila, genes in early developmental pathways differ in Apis, whereas similarities exist for functions that differ markedly, such as sex determination, brain function and behaviour. Population genetics suggests a novel African origin for the species A. mellifera and insights into whether Africanized bees spread throughout the New World via hybridization or displacement.
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Being a child is a critical time in life, the foundations for a healthy adult are being set up. This is the time when bones are growing and hardening, the brain is developing, and hormones are raging. With all of this going on in a small body you can imagine that a lot of vitamins and mineral are needed for healthy development to take place. Ideally your child will get what they need from a well-balanced diet. But let’s face it, kids are picky eaters, we all live a fast-paced lifestyle and need to be in two places at once. Other reasons a child may not be getting the nutrition they need is if they have a chronic condition that inhibits them from absorbing vitamins like diabetes or asthma. Also, some kids drink carbonated beverages but that can leach vitamins out of their system. What vitamins are the most important for your child to get? And if they aren’t getting through their food exclusively what are other option? Let’s dive in! Some Essential Vitamins for kids: - Vitamin A-this is necessary for the growth of tissue, skin and bones, aids in eyesight and helps the immune system to function. Food sources: eggs and yellow/orange vegetables like carrots or squash. - B Vitamins- this is a whole group of vitamins that are necessary for a healthy metabolism, energy production and to keep the nervous system communicating to the rest of the body. Food sources: chicken, fish, eggs, nuts, beans, cheese. - Vitamin D- promotes healthy cell growth and inhibits cancer cell production, helps form teeth and allows the body to absorb calcium. Vitamin D is a fat-soluble vitamin which means you can have too much and they are toxic in high doses. Food sources: fatty fish, although the best source is straight from the sun - Calcium-needed to form strong bones! Food sources: cheese, yogurt, tofu, leafy greens such as spinach - Iron- helps the red blood cells of the body carry oxygen to all the areas of the body. Getting enough iron is important for all children but especially for girls once they start menstruating, they are at higher risk for anemia at that time. Food sources: beef, turkey, pork, beans, prunes, beans. Some other vitamins kids may need are Vit C, Magnesium, Vit E, Selenium, Potassium and Zinc. All of these can be found in a good multivitamin. Especially if you have a hard time getting your child to eat a balanced diet it can be crucial to supplement. The only way to know if your child is truly deficient is a blood test. But it won’t hurt your child to take a multivitamin, if their body doesn’t need it then it will simply be eliminated. As a parent you might be wondering how you will get your child to swallow a multivitamin. The good news is that you can find them in liquid form. One that we recommend a lot here in the office is Kidzplay by Systemic Formulas. It is lightly sweetened with stevia to make it more kid friendly which means it is not full of sugar like a lot of common brands found in gummy form. It is a good idea to always be aware of where you are getting your supplements from. Companies that submit their products to be tested by an outside source are more reliable than companies who don’t because the FDA does not regulate supplements. You want to ensure that you are getting what you are paying for and the correct nutrition for your kids! If you have questions about a supplement or need more options for your kids comment below.
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Monument record SFT 008 - 12,420 coins in pot (Lower Empire, 1 ? Tetricus). Please read our guidance about the use of Suffolk Historic Environment Record data. |Grid reference||Centred TL 9527 6880 (100m by 100m) (Approximate)| |Civil Parish||STOWLANGTOFT, MID SUFFOLK, SUFFOLK| Type and Period (1) 12,420 coins in pot (Lower Empire, 1 ? Tetricus). From "a field half a mile below church". Found in 1764 (S1)(S2)(R2). OS locates hoard at TL 953 688 approximately from sketch map although TL 9527 6880 more precise approximation (S1). Coins found 'near Barbers Lane, Stowlangtoft' (R2) (R3) is a confusion with the coin hoard found at Barbers Lane, Langham (LGH 003. - <R1> SSF50032 Index: OS. OS Card. OS, card TL96NE6. - <S1> SSF50042 Bibliographic reference: Suffolk Institute of Archaeology. Proceedings of the Suffolk Institute of Archaeology. PSIA, 1, 1848, 75. - <S2> SSF21915 (No record type): Suffolk Tourist, nd (circa 1820), 110. - <R2> SSF54455 Bibliographic reference: 1911. VCH Suffolk 1. 318. - <R3> SSF3104 (No record type): Camden, Brit 2, 86. - <S3> SSF50040 Bibliographic reference: Barker, H. R.. 1907. West Suffolk Illustrated. - None recorded Related Monuments/Buildings (0) Related Events/Activities (0) Record last edited Jun 19 1995 12:00AM
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This article was written by Laraine. I’ve been a carnivore for most of my life. However, about six years ago, I decided to become a vegetarian. Before becoming a vegetarian, I’d often contemplate the chunk of meat before me, wondering about its life and its untimely death. The chicken, cooped up in squalid and overcrowded conditions, is sent to the slaughterhouse after 40 days. All this for the sole purpose of ending up on our chopping boards. As an animal lover, there’s always been an underlying sense of guilt in me, and the aha moment came when I was talking with some fellow animal lovers. One of them questioned the difference between consuming dogs, cats, pigs, chickens, and the like. His question made me think. Is there a huge difference between animals and us? If humans believe that humankind is superior and above all other creatures, isn’t it our responsibility to be guardians of all life? It was then that I decided that I should become a vegetarian. Why did I choose to become a vegetarian I adopted vegetarianism for 1) the love of animals—you guessed it—and 2) our planet. Our food system is pegged to controversies surrounding animal welfare and climate change. Yet, we’re sometimes unaware because we’re so distant from the process; we only see them nicely packed in supermarkets, and it’s easy to ignore everything that happened before that. A farming system filled with misery Image source: Animal Equality International “The farming system we rely on is woven through with misery,” says American novelist Jonathan Safra Foer’s opinion piece for NY Times. It’s time to face the grisly reality of the inhumane treatment of the animals in the food system. Chickens in factory farms are shackled in overcrowded and squalid conditions, with little space to move, let alone forage and explore as they are naturally inclined to. The chickens have been genetically modified, which affects their hearts and lungs, often resulting in chronic illnesses. Such inhumane treatment doesn’t just happen in the meat and poultry industry. It occurs in the dairy industry as well, where production diseases like mastitis, lameness, and infertility are common. Also, calves are separated from their mothers before weaning, which may increase their mortality rates and vulnerability to diseases. Some dairy farmers, however, “remained sceptical of the health and welfare for the cows and calves”. More research on cow-calf separation is still ongoing, but the sight of the helpless mother cow chasing after its calf is so heart-wrenching. I’m not dairy-free yet, but I’ve been trying really hard to cut my intake. Our addiction to meat is killing the planet Let’s face it: our diet puts a heavy toll on the environment. As Mike Barrett—the executive director of science and conservation at the World Wildlife Fund—says, “We live on a planet where nature is being squeezed out,” and I couldn’t agree more. Here’s why: According to the Food and Agricultural Organisation (FAO), approximately 60% of the agricultural land is used for rearing livestock. Image source: World Resources Institute According to the diagram from World Resource Institute (above), rearing beef requires approximately twice as much land per gram of protein as chicken and pork. It also requires 20 times more land and emits 20 times more greenhouse gases than the equivalent amount of plant-based proteins. Thus, it’s not surprising that beef production is the leading cause of deforestation in tropical rainforests such as the Amazon. On top of that, a quarter of the world’s greenhouse gas emission is pegged to agriculture and other related land use (i.e., soy cultivation for animal feed). Greenhouse emissions from livestock include methane, typically from Bovine belching—cow burps—and it can be up to 34 times more damaging to our planet. In contrast, a plant-rich diet would require fewer resources like land and water, emit less greenhouse gas and help to improve the welfare of our animals. It also frees up more agricultural land, which is vital to feed a growing world population. What I enjoy about being a vegetarian Being a vegetarian has its benefits as well; it’s easier on our pockets and better for our health! Plant-based proteins like tofu, lentils, tempeh, and chickpeas are more affordable than animal proteins. With a wide variety of choices available, it’s easy to whip up delicious meat-free and healthy meals! Studies have shown that a plant-rich diet may help to reduce the risk of heart disease, stroke, diabetes, and cancer. Personally, I feel less sluggish (no more post-meal food coma!), and my digestive system’s much happier; if you know, you know. 😉 Five tips for becoming a vegetarian We need to change the way we eat, but that doesn’t mean you have to give up meat entirely if you don’t want to; check out NY Times food reporter Melissa Clark’s tips for eating less meat. But if you’re keen on becoming a vegetarian, here are some tips for you: 1) Take baby steps You don’t have to change your diet overnight. Instead, you can do it slowly and gradually. For example, you can start by going meatless once a week, or be a weekday vegetarian, etc. You can try being a pescatarian too, if you like seafood (try to choose sustainable choices if possible). The key here is to start slow so you can maintain your vegetarian diet easily. 2) Know your ingredients Understand the ingredients available to you, and look for meatless options! You’d be surprised, like I was when I first discovered the different soy proteins like soy chunks, soy sheets, soy sticks, etc. If you’re searching for that familiar texture of meat, there are many meatless options available in the supermarkets, such as Beyond, Quorn, and Impossible, to choose from. Find out your favourite ingredients and build a recipe for yourself from there. If you’re interested, you can read up on improvisational cooking! 3) Experiment and have fun Get creative with different vegetarian recipes, and grab a friend to join you! Look for recipes online, bookmark your favourite recipes, and have a cooking date together. An extra pair of hands won’t spoil the soup; it’d be double the fun! 4) Plan ahead Meal prep is my favourite thing to do on the weekend. I love planning recipes and reinventing the leftovers (because who likes to eat the same thing five times a week) to keep food waste to a minimum. Also, it’s handy to take note of the vegetarian restaurants around you or the places you’re heading to! It makes it easier for you to stick to your diet. Pro-tip: you can save restaurants on Google maps! 5) Be kind to yourself This is the most important tip! Always be kind to yourself, don’t be too hard on yourself if you missed one of your Meatless Mondays. The guilt can get to you and make your journey harder. Again, you don’t have to force yourself to go meatless entirely overnight. It’s a lifestyle change after all, and it will take time. Go slowly and gradually! I’m not trying to make you a vegetarian (but if this convinced or inspired you, then hurray!); I’m trying to leave you a tiny breadcrumb trail and hopefully set you off on your less-meat-more-plants-diet journey. We can only make better choices if we’re more aware of the impacts of the food we eat. Keep yourself updated by reading or watching documentaries.
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YONKERS, N.Y. (CN) - There is no public-health threat after a tanker spilled 2,100 gallons of oil near the Bronx River, New York officials said Tuesday. A spill-response team with the state Department of Environmental Conservation was quick to join Yonkers firefighters Monday morning when the spill occurred at 125 Bronx River Rd. The road and a parkway of the same name separate the spill from the Bronx River, which runs into New York City, 23 miles south of the Kensico Dam in southern Westchester. In addition to quickly containing 1,500 gallons from the spill Monday, firefighters pumped impacted sewer infrastructure, the DEC said. Though the DEC has not named the company responsible for the spill, it did note that this company has hired TriState and Ken's Marine to control outfall to the river, "using sorbent pads to soak up oil along the Bronx River shoreline." The DEC said its staff remain at the scene to supervise the ongoing cleanup efforts and to investigate contamination of the Bronx River. Bronx River Road becomes Webster Avenue, in the Woodlawn section of the Bronx, two blocks below the spill site. The DEC described conditions as improved Tuesday, adding "that there is no immediate threat to public health as a result of the spill." Conservation efforts over the past century have had much success in reclaiming the river from industrial peril. Mohegan Indians called it Aquehung, or the River of Hugh Bluffs. Beavers once dominated the river landscape but early settlers hunted the mammal to local extinction in the 1800s. Though the river's cleanup has brought sightings of at least two beavers in recent years, pedestrians and bicyclists are more apt to see ducks, turtles, great blue heron and geese dotting the terrain. Read the Top 8 Sign up for the Top 8, a roundup of the day's top stories delivered directly to your inbox Monday through Friday.
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Have you recently started a new business? Or you’re thinking about starting your journey as an entrepreneur? Either way, congratulations to you! You’re taking a major step towards a rewarding and more independent lifestyle. That being said, owning a business comes with certain challenges. Here are the crucial areas that you’ll need to make an effort to understand and become familiar with if you want to take control of your business: Identify Your Brand One of your first challenges as a business owner is to build a unique brand. Creating a relevant and distinctive logo is only the first step when it comes to branding. What’s most important is identifying the crucial characteristics that set you apart. This is sometimes referred to as USP (Unique Selling Proposition) and will inform your marketing, the kind of content you post on social media, and how you communicate with your customers. Your brand identity should be consistent across platforms both online and offline. So, figure out what makes your brand unique. Know Your Customers No one should know your customers better than you. Who are they? What problem of theirs are you providing a solution for with your product or service? Once you’ve answered these questions, you’ll want to go ahead and dive deeper by developing a unique buyer persona. A buyer persona is a fictional character who represents your ideal customer. Some businesses even go as far as giving their buyer persona a name and a very specific lifestyle to bring them to life. For example, “Mary is a married 35-year-old mother of two who works in middle management. She drives a Honda Accord and enjoys reading mystery novels, yoga, and gardening.” Of course, you have to base your buyer persona on research to ensure it’s as accurate as possible. In some cases, you may have more than one. Your buyer persona (s) may change over time as your business evolves. Be sure to review or update it as your business grows. When’s the last time you reviewed and updated yours? Pay Attention to Your Numbers Few people start a business because they enjoy crunching numbers. However, it will be hard for you to succeed if you don’t thoroughly understand your expenses, taxes, profit margins, and other essential numbers. Here are a few tips to help you in this area: - Research the best business structure for your needs. Many new entrepreneurs start as sole proprietors. However, it’s often advantageous to set up an LLC, Corporation, or Partnership. If necessary, consult with an attorney. Setting up a business entity helps protect you legally in case your business is ever sued. - Invest in quality accounting software. You may want to hire a part-time or full-time bookkeeper or accountant. You can also outsource these tasks to an agency as you need them. Whatever you decide to do, just promise me you don’t just try to “wing it” as this can lead to serious financial problems for you and your business in the future. - Be frugal when starting out. You don’t have to invest in costly office space, equipment and non-essential amenities. Consider renting rather than buying expensive equipment or perhaps consulting with other small business owners and splitting the costs. - Always track the ROI of your marketing campaigns. With online advertising such as Google AdWords or Facebook ads, you can use software to track your results. Important digital marketing metrics include conversion rates, cost per customer acquisition, and click rates for email campaigns. Regardless of what type of marketing you do, it’s essential to measure your results. Manage Your Time When you’re an employee, your time is generally managed by your employer or a manager. When you run your own business, however, you are entirely responsible for setting your schedule. You need to set daily, weekly, and long-term goals for yourself. But where do you even start? - Prioritize. When you create your to-do list, try to arrange it, so you complete the most urgent and difficult tasks early in the day. - Use time management tools to track your time and see what you’re spending the majority of your time doing. Use the results to determine how you can better be productive with your time. - Avoid getting caught up in busy work. You can fool yourself into feeling productive while endlessly “researching” on Google, browsing social media, and holding long meetings. - Learn to say “no.” You’re not obligated to listen to every sales pitch or attend every event to which you’re invited. - Delegate and outsource. You only have so many hours in a day to get things done. When you delegate tasks, you have more time to devote to more essential matters. As your business grows, you’ll be able to identify more areas to delegate and outsource. This is one of the secrets to upscaling your business. Feeling overwhelmed? Don’t worry, this is a lot of information to take all at once, but you’re not alone, there are resources and business coaches that can help you clarify your needs and develop a successful strategy for your business. I’m Nadia La Russa, and I’m a serial entrepreneur in Thunder Bay, Ontario who provides business coaching for entrepreneurs all over North America. I can help you take control of your business so you can reach your true potential. Click here to get in touch and find out how my business coaching can help you. P.S. If you’re feeling excited about taking control of your business but aren’t sure when to start because you’re always so busy, be sure to read this blog post I wrote on how to take control of your time. After all, we all have the same hours in the day as everyone else!
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28 Oct Top 5 Things to Remember When Sending A File to Print When you have a great design that you and your team spent hours perfecting for your t-shirt, brochure, or a direct mailer, it is vital to make sure your files head to the printer in the correct format, size, color, and resolution. We wrote previously on formatting document files for promotional printing, and below, we give you five ways to produce files in tip-top shape for printing! As you prepare to send your files off to be printed, follow these tips below to get your incredible design producing the best results. - When preparing a print file: do not increase the size of a low-res file When you increase the size of a low-resolution file, all you end up with is larger pixels and a heavier, blurry image. Pixels do not change; they just expand and contract to fill available space. Instead, work with small low-res images, or, as always, it is best to send in a high-res image. If you are looking to improve the resolution of images, most often it will require professional photography or at the very least a very high-resolution camera. - When preparing a print file: consider leaving off drop shadows and fading When sending in files for t-shirts, be sure to avoid drop shadows, fade effects, or anything that’s transparent for DTG (direct to garment) prints. These effects can produce unwanted areas on shirts, making them look faded, grainy, pale, and even giving the appearance of discoloration. If you are looking to add special effects to your printing, consider embossing, foil stamping, or using metallic inks on your final product. This works well with paper print products such as business cards, letterhead, envelopes, and direct mailers, and your local printer may have specialty inks in store! - When preparing a print file: Choose your colors wisely Neon colors that are reminiscent of the 80s are finding their way into designs of late. We get that they are hype, but we encourage you to be carefully when choosing colors to achieve dramatic results. When using neon, note that the color result may not appear as you expected. Neon colors look vibrant on a screen; however, when printed, they tend to be out of printable color range and therefore appear dull, thus leading to disappointing results. Screens make colors look brighter because they are backlit, so when choosing colors, note that neon is difficult to hold brilliance once printed. Also consider color choices from your screen to print files, as your artwork is going to be printed in CMYK (cyan, magenta, yellow, and key) and thus needs to be sent to the printer in this format. When designing, you can work in RBG, but you need to convert images to CYMK before sending. There are ways to do this easily, such as calibrating your monitor, and you can find sources to help with this online. - If requesting embroidery, simplify your design before sending to print If the item you are wanting to send in requires embroidery, note that complex embroidery areas might need to be simplified. Small, complicated, and detailed embroidery designs don’t always produce expected results. Consider giving your designs a little breathing room to make your images and text easier to be seen, read, and noticed by others. Print product graphics may not work for embroidery. These files have to be the actual embroidery area dimensions, and text must be at least 0.25” in height and at least 0.05” thick. Stitch density and direction differ depending upon what you are getting embroidered; for example, hat and apparel embroidery are often different. These require specific adjustments to ensure files work completely. - When sending in your file for printing, ensure your dimensions, dpi, and image size are correct Dpi stands for dots per inch, and when discussing dpi for print files, we are talking about pixels per inch but still refer to it as dpi (not PPI). When sending a file in to be printed, the file should be at least 300 dpi for a hand-held printed piece, such as a flyer or brochure. Posters need a minimum resolution of about 100 dpi and billboards about 20 dpi. When considering dpi, a great thing to remember is to err on the side of resolution that is too high rather than too low. But dpi is not enough—you need to know the size of the image as well. When sending in 300 dpi, this means that each inch is 300 pixels across. If an image is 8 inches wide, there are 2,400 pixels in that width (8 X 300). Likewise, if an image is 12 inches long, the image is 3,600 pixels in length (12 X 300). To get the total pixels, multiply the length times width for a total of 8,640,000 pixels. Once you have the number of pixels within an image, you can get file size. If the image is grayscale, each pixel is 8 bits, or 1 byte in file size, therefore producing an image that is 8,640,000 bytes, or 8.2 MB. This knowledge will lend itself to a more specific understanding of images. In summary, know dpi as well as image size before sending your file off to the printer. Assistance with Preparing Print Files at Acme Printing in When you spend hours with your team to perfect graphic design, you want to ensure that your ideas are printed correctly. Preparing a file incorrectly is the most common problem seen prior to starting a print project. Above, we outlined 5 things to prepare for when sending in your files to be printed. If the process is still daunting to you, there is another way. If you are just getting started with promotion, we understand how overwhelming it can be to produce a quality design and then correctly send the file off to the printer. At Acme Printing, we have been in the print business since 1967, and our years of expertise prove that we can be the answer to your company’s needs. Whether preparing your file to print, looking to have a banner made, or wanting an entire brand refresh, we can help. Our graphic designers, print coordinators, and team are ready to help you. Reach out today by calling 423-581-8528, or through our contact page.
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Background: Diabetic foot wounds, particularly those secondary to amputation, are very complex and difficult to treat. We investigated whether negative pressure wound therapy (NPWT) improves the proportion and rate of wound healing after partial foot amputation in patients with diabetes. Methods: We enrolled 162 patients into a 16-week, 18-centre, randomised clinical trial in the USA. Inclusion criteria consisted of partial foot amputation wounds up to the transmetatarsal level and evidence of adequate perfusion. Patients who were randomly assigned to NPWT (n=77) received treatment with dressing changes every 48 h. Control patients (n=85) received standard moist wound care according to consensus guidelines. NPWT was delivered through the Vacuum Assisted Closure (VAC) Therapy System. Wounds were treated until healing or completion of the 112-day period of active treatment. Analysis was by intention to treat. This study has been registered with ClinicalTrials.gov, number NCT00224796. Findings: More patients healed in the NPWT group than in the control group (43 [56%] vs 33 [39%], p=0·040). The rate of wound healing, based on the time to complete closure, was faster in the NPWT group than in controls (p=0·005). The rate of granulation tissue formation, based on the time to 76-100% formation in the wound bed, was faster in the NPWT group than in controls (p=0·002). The frequency and severity of adverse events (of which the most common was wound infection) were similar in both treatment groups. Interpretation: NPWT delivered by the VAC Therapy System seems to be a safe and effective treatment for complex diabetic foot wounds, and could lead to a higher proportion of healed wounds, faster healing rates, and potentially fewer re-amputations than standard care. ASJC Scopus subject areas
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Lilongwe City Council (LCC) has a total budget of MWK 5.9 billion for the 2021-2022 financial year, of which MWK 5.1 billion is financed by Locally Generated Revenues (LGR) and MWK 754 million by Government Transfers. Central Government has also committed an allocation of MWK7.6 billion for upgrading of roads in the City in addition to MWK660 million which is administered by Road Fund Authority. The 2021-22 budget has been allocated towards implementation of programs to achieve the outputs in the 2020-2025 strategic plan. The plan is supported by a detailed “roadmap to success,” and is divided into 3 components and 18 strategic objectives (SOs). The 18 strategic objectives are in the following areas: Budget Reform, Revenue Collection; Asset and Liability Scrutiny, Good Governance and Organizational Culture; Public Private Partnerships; Par; Restructuring; Performance management; Private Sector Development; Parks and the Environment; Solid Waste Management; Transport; Public Health; Town Planning; Investment Program; Primary Education; and Youth and Sports. For detailed information, find below 2021 financial reports.
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The new Lilie Hub: helping Sexual Health Services (SHS) manage their online appointment booking system with ease When COVID-19 struck, the world went into reset mode and disrupted our normal way of life in a lot of ways. It also led to many unexpected positive changes – from nature bouncing back to the dramatic shift in flexible working. In addition, the lockdown was also a ‘game-changer’ for sexually transmitted infections (STIs) – given that isolation meant people couldn’t have sex with new partners and pass on infections. Data reveals that the number of STIs in England fell by almost a third last year. But that statistic doesn’t provide the full picture. The drop in STIs may be due to social distancing measures. However, experts suggest that it is also because fewer tests were conducted. According to Public Health England (PHE), diagnosis of STIs decreased in 2020 by 32% compared to 2019. This was further confirmed by Dr Mark Lawton, a sexual health consultant and spokesperson for the British Association for Sexual Health and HIV (BASHH), who commented, “We’ve undoubtedly seen a reduction in the number of people getting tested during the lockdown.” This is a point of concern, so what are the underlying reasons for fewer people getting tested and how can they be addressed? Impact of COVID-19 on Sexual Health Services (SHS) According to Dr John McSorley, president of BASHH, “COVID-19 has had a stark and concerning impact on SHS.” Disruption to health services due to the coronavirus outbreak contributed to a steep drop in STI diagnoses in the UK. 54% of UK SHS closed, and 38% of sexual health staff were moved to work in other parts of the NHS. Under government guidance, healthcare services were required to reduce avoidable footfall. Hence, SHS had to quickly adapt to the change in the type of appointments offered in order to protect patients and staff from the risk of infection. A vast reduction in face-to-face consultations were replaced by telephone appointments only. As a result, patients faced consistent problems with booking appointments for regular sexual health check-ups, treatments, and medication reviews. When phoning services, longer waiting times and not being sure when their healthcare provider would call back left patients feeling anxious. Plus, as the pandemic progressed, there were fewer consultations for patients aged less than 25 years – an age group where STIs are most common due to behavioural, biological, and cultural reasons. Rise in STIs post lockdown underlines the need for urgent action With the focus on coronavirus-positive patients, clearly, there was a reduction in testing for HIV and STIs by SHS and specialised HIV services. Besides, there was the additional fear of catching COVID-19 which also caused people to delay care and not receive the treatment they needed to manage their condition. Together, it led to the increased spread of infections. Consequently, as clinics reopen, STI rates are again on the rise. With restrictions easing, treatment for STIs is soaring. “We’re seeing a resurgence of all the traditional STIs”, adds Dr Jane Dickson, a consultant in sexual and reproductive healthcare at Aneurin Bevan University Health Board in Newport, South Wales. So, what action can be taken to combat this continued rise in infections? Lilie Hub: digitising appointment bookings for SHS If only booking medical appointments was as simple as booking a flight or a movie ticket, STIs could have been managed better – irrespective of the pandemic. That’s where Lilie Hub comes in – facilitating online engagement between patients and SHS. Lilie Hub is a new, innovative, browser-based patient appointment booking system for SHS that helps more people get tested – conveniently, securely, and confidentially. It allows patients to book and cancel appointments and provides them with a choice of when they want an appointment booked in and where – be that telephone or face-to-face consultations, where appropriate. Patients can access Lilie Hub via a web browser on their laptop, tablet, or smartphone and have at-a-glance information about what facilities the service offers. Medical staff and clinicians can prioritise and deliver care according to patient preference and needs. By empowering patients to manage their own appointments, Lilie Hub aims to free up clinical and administrative resources, making sure staff are available to focus on operational efficiencies and improved care delivery. Accelerating remote care for SHS The idea behind Lilie Hub is to help SHS provide as much care as possible to the patient – conveniently. To facilitate this, Lilie Hub allows services to configure booking reasons for patients to choose from – thus ensuring they’re booked into the appropriate clinic. It also enables SHS to triage patients – allowing the patient to answer appropriate questions (if required) outside of the consultation appointment. The Online Dynamic Forms for Lilie Hub – designed for triage questions and to be completed by patients whilst booking an appointment – results in reduced consultation time spent by clinical staff. Empowering patients with self-help choices Harnessing the power of online digital services, Lilie Hub offers a discrete, self-service to help manage the patient journey confidentially and with ease. It allows patients to contact their service via a link from the SHS Lilie Hub website, book and cancel an appointment, and answer clinically relevant information (triage). By enabling patients to create an account and log on to change personal details, contact restrictions, and previous/current appointment information, Lilie Hub helps update patient records and streamline existing workflows for SHS – subsequently cutting down administrative time. Furthermore, the Identity Management Service embedded within Lilie Hub enables patient matching to aid the reduction in duplicate patient records. Scaling up digital services to combat STIs Before the outbreak of the pandemic, most SHS offered face-to-face/ telephone or walk-in options for booking appointments. However, with the introduction of Lilie’s new online booking facilities, access to care is changing – making it easier for SHS to deliver faster and more efficient care. Digitising appointment bookings not only helps patients and care providers set their schedules but also saves time, reduces error, improves organisational efficiency, and enhances the patient experience. And nowadays, with just about everyone having a smartphone in their pocket and less time than ever, it’s inevitable that platforms like Lilie Hub will transform the way SHS work – positively affecting patient lives. For more information on Lilie Hub, click here or contact us at firstname.lastname@example.org.
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Museums Liverpool – Walker Art Gallery From Burne-Jones to Banksy, fantastic changing exhibitions and a dedicated children’s gallery… all for free The Walker Art Gallery, in Liverpool has beautiful paintings, sculpture and decorative art from the 13th century to the present day. The Walker Art Gallery in Liverpool has one of the most impressive collections of fine and decorative art in Europe and is renowned for the depth of its Renaissance and Pre-Raphaelite collections. It is home to outstanding works by Rubens, Rembrandt, Poussin and Gainsborough and Rossetti. Baby changing and prams There are baby changing facilities on the first floor. Prams can be stored in the ground floor cloakroom. Things to see and do - The Big Art for Little Artists gallery on the ground floor is designed specially for children and is very popular. - Check the ‘What’s on’ listings for family-friendly activities to do at the gallery. - Our monthly Family enewsletter has details of our free family exhibitions, events and activities. Sign up through our register with us page. In the gallery - Assistance dogs are welcome. - There are two wheelchairs available to borrow on request at the information desk. - The building is accessed via a ramp to the right of the main entrance and there is a lift for access to the first floor. - There are wheelchair accessible toilets on the ground floor. Group leaders wanting to organise sessions for visitors with special needs should contact our education team on 0151 478 4788. Williamson Brown Street, Liverpool 0151 207 0001
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Social media marketing is such a fascinating field to work in. Finding just the right combination of content, sales service, and customer relations for maximum return is exhilarating, and a passionate social media marketer can really grow a brand’s social media presence. Customers want to be engaged, and one way a brand can optimise engagement with customers is through social CRM activities. This article takes a look at what exactly social CRM is, and why businesses should adopt social CRM activities to improve their customer relations: Social CRM defined Customer Relationship Management (CRM) software began as databases of customer contact information and customer behavior data which were merged. In the 30 years which have transpired since then, CRMs have become companies’ central nervous systems. CRM platforms supply organisations with multi-dimensional customer profiles which assist with predicting, controlling and automating sales practices while, at the same time, continuing with the process of collecting information. Through the introduction of social media, organisations are better able to collect customer data as well as track online behavioyr through open social channels. Social CRM software combines social information with a company’s existing CRM software in order to give a thorough overview of an individual’s online behaviour. Did you know that 65% of customer service teams use social media? Customer relations management and social media were bound to intertwine sooner or later, and many prolific CRM tools now seamlessly integrate social media channels alongside traditional CRM activities. This makes it possible for companies to communicate directly with customers through their preferred mediums of interaction. Like any CRM system, a social media CRM allows managers, statisticians, and other interested parties to engage and interact with clients in a range of ways. These include through telephonic conversation, text message, instant message, email, or social media. Social CRMs also track key metrics to offer informed, actionable insights for improvement.
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With Australian electricity prices amongst the highest in the world, more and more households are going solar. The big power companies say the Renewable Energy Target is undermining their businesses and they want it wound back. The federal government agrees, so who is to blame for the high price of power? Jess Hill investigates. Never has it been more expensive to turn on our appliances. In the last few years, our power bills have doubled, making Australia's electricity prices some of the highest in the developed world. Prime Minister Tony Abbott blames two things: the carbon tax and the renewable energy target. He says the government's review of the target will look at its impact on bills, because 'renewable energy targets are significantly driving up power prices right now'. From the coal-fired power station point of view, you couldn't have a worse competitor, because solar is at its best when the market is at its most profitable. But Mr Abbott's claim that the renewable energy target is expensive is not supported by the data. The Australian Energy Markets Commission says the renewable energy target adds four per cent to the average electricity bill. For an average household, that's about a dollar a week. 'For all of the attention that carbon price has got, from the increasing attention the renewable energy target's got, the main reason that electricity has been getting dearer is the overinvestment in poles and wires, and the fundamental inefficiency in the way that the national electricity market's working,' says Richard Denniss, executive director of the Australia Institute. Federal Treasury estimates that 51 per cent of an average household bill is spent on network costs. Most of that is going towards paying off the $45 billion network companies have spent on updating our poles and wires over the last five years. This investment was justified by the network companies' own data, which showed that Australia's energy demand was going to increase dramatically. But in 2009, just as they were beginning to spend, something unprecedented happened. Energy demand in Australia didn't go up—it went down. And it's continued to go down every year since. Despite the clear reality of falling demand, the network companies insisted that demand was rising, and they carried on investing billions of dollars into the grid. Every dollar of that investment is now being recovered from consumers, via our power bills. Every dollar, plus ten per cent—a guaranteed return granted to them by the regulator. In 2012, three years after the spending began, the Senate held an inquiry into electricity prices. It was chaired by Labor MP, Matt Thistlethwaite. 'What we found was those network businesses—that earned the most profits were the ones that invested the most,' he says. 'So there was a perverse incentive in the system for an overinvestment in the poles and wires, and that led to dramatic profits for those businesses, but of course it was the consumer that paid for that cost of that additional capital.' Mr Thistlethwaite says that the inquiry was presented with many examples of infrastructure being built where it wasn't needed. 'We discovered a network business that had invested $30 million in a substation in Newcastle, and I actually visited the substation. It wasn't connected to the grid. The reason why it wasn't connected to the grid; when the decision was made a couple of years ago to invest in this particular piece of infrastructure, it was projected that the demand would be there. But the demand didn't eventuate.' Energy analyst Bruce Mountain from Carbon Market Economics says that although some old infrastructure needed updating, the amount of money wasted on the poles and wires was substantial. 'I would estimate as an aggregate across the national electricity market, perhaps at least a half of that total spend was not actually necessary, but it does vary by state.' The staggering rise in electricity prices brought on by this investment has had a rather unintended consequence. 'Because the price got so high, it made solar even more competitive from the customer's point of view,' says David Leitch, a utilities analyst with UBS. 'Because when you use the solar in your house, you don't use the wires and poles in the system, so you're eliminating half the final price.' The fact that households with solar can save more than half on their power bills has made solar panels an economic choice, not just an ethical one. There are now 1.2 million households getting their daytime power from solar panels. 'It's essentially turning households into competitors of the electricity companies, because all of a sudden households are producing electricity, and they're deciding what to do with it,' says Mr Leitch. 'As opposed to just having a choice of take it or leave it from your friendly electricity retailer.' This article represents part of a larger Background Briefing investigation. Listen to Jess Hill's full report on Sunday at 8.05 am or use the podcast links above after broadcast. Solar rooftops are wreaking havoc on the traditional power industry, says Mr Denniss, because they produce the most amount of energy at the time of day when the power industry makes the most money. 'Solar panels have got this great trick, they make lots of electricity when the sun is shining; that's when we like to turn our air conditioners on,' he says. 'When everybody turns their electricity on at four o'clock on a hot Thursday afternoon, we have enormous demand for electricity for these short periods of peak demand. And that's when solar panels are at their best.' 'Solar panels are actually pumping quite a large amount of energy in during these periods of peak demand, and that's pushing down the peak price. Now that's great for everybody, except the so-called baseload power stations. Because the baseload power stations used to be able to sell their electricity for a much higher price at four o'clock on that hot Thursday afternoon. From the coal-fired power station point of view, you couldn't have a worse competitor, because solar is at its best when the market is at its most profitable.' What that means is that the big coal-fired power plants are earning less for the energy they produce. That's because Australia has more electricity than it can use. That's a big problem, says the federal industry minister, Ian Macfarlane. 'We're facing an enormous challenge in terms of an excess generating capacity in electricity in Australia. To be adding large quantities of generation into that situation has to be questioned. The review process will go through those things.' With energy demand going down, and renewable energy supply going up, Australia simply doesn't need as much power from fossil fuels anymore. In the last few years, several large coal-fired power stations have been shut down or mothballed. 'Australia doesn't need more generation; if we have more wind at the moment, it will displace some other form of generation,' says Mr Leitch. 'So no-one wants to be displaced in this world, and we can all understand that.' That's one of the reasons why the conventional power industry is lobbying the government to wind back the renewable energy target—known as the RET. The Energy Supply Association of Australia, which speaks on behalf of the conventional power industry, says that now demand has gone down, 41,000 gigawatt hours will represent around 30 per cent of Australia's energy supply, rather than 20 per cent. 'The conditions under which the RET was designed no longer exist, and we think the RET is broken and can't work in an oversupplied market,' says Matthew Warren, the ESAA's CEO. But there has already been a review. At the end of 2012, the Climate Change Authority reviewed the target and recommended that it be maintained. Their review was supposed to provide certainty to the renewable energy industry. The chair of the Climate Change Authority is Bernie Fraser, a former Reserve Bank governor. He says that just by holding another review, the government has ensured that the 41,000 gigawatt-target won't be met. 'Investment is actually being cut back and delayed, and I think because of that, I think it's apparent now that the 41,000 gigawatts for large renewable energy power plants, is not going to happen. It's going to be a lesser figure and I think that's what the opponents, the critics of renewable energy want to see.' 'Policymakers need to look beyond short-term economic considerations in the interests of some of the big companies to longer-term community interests. And that's what governments are supposed to do, but unfortunately it's not happening at the present time,' he says. So it's a bit… well, it's more than a bit, it's very disappointing that we're falling behind, and we are falling behind what many other countries are doing.' - Jess Hill, reporter - Anna Whitfeld, researcher - Linda McGinness, supervising producer - Andrei Shabunov, sound engineer - Chris Bullock, executive producer
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Gibbs Law Group LLP is investigating injuries resulting from the use of Nizoral. According to the FDA, Nizoral (ketoconazole) oral tablets, which are used to treat fungal infections, can lead to adrenal gland insufficiency and potentially fatal liver injury. On July 26, 2013, the FDA released a safety alert and required changes to Johnson & Johnson’s Janssen Pharmaceuticals Nizoral tablet labels. The European Medicines Agency (EMA) recommended suspension of marketing ketoconazole after the Committee on Medicinal Products for Human Use found the risks do not outweigh the benefits. The review of ketoconazole was prompted by the suspension of the drug in France, where the French medicine agency had also found that the benefit-risk balance of the drug was negative. New Warnings against Nizoral Oral Tablets Due to serious side effects that include liver injuries, adrenal gland problems, and adverse drug interactions, the FDA required a label change and recommends limited use of Nizoral. The Nizoral label now states, “NIZORAL® Tablets should be used only when other effective antifungal therapy is not available or tolerated and the potential benefits are considered to outweigh the potential risks.” The FDA also requires the label include a new contraindication that patients with liver disease should not use Nizarol. The EMA has taken a further step in recommending that anyone taking ketoconazole make an appointment with their doctor to discuss the treatment and that doctors should stop prescribing the antifungal medication. Nizoral has been used to treat blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis as well as Candida and dermatophyte infections. According to the FDA, ketoconazole should no longer be prescribed for Candida or dermatophyte infections. The FDA warns that Nizoral has led to: - liver injuries (also known as hepatotoxicity), including damage leading to liver transplantation or death; - adrenal gland problems due to insufficiency from decreased corticosteroid production; and - dangerous drug interactions, including life-threatening problems such as heart dysrhythmia. The FDA and EMA warnings apply only to the ketoconazole oral formulation, which usually comes in 200-mg tablets and was prescribed over 600,000 times in the United States last year alone. If you or a loved one developed a liver injury, adrenal gland insufficiency, or other serious complications after taking Nizoral oral tablets for fungal infections, you may want to speak with an attorney to learn about your rights. Free and confidential consultations with our personal injury lawyers are available by calling toll-free (866) 981-4800 or filling out the form to your right.
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Investigation of ignition and combustion processes of solid fuel particles under oxy-fuel conditions This project addresses the influence of the turbulent flow field on the ignition and combustion processes of different fuel particles as a function of particle loading. For this purpose simple flow configurations will be used which can be operated in a reproducible manner with defined boundary conditions while varying the relevant chemical, thermodynamic and flow-mechanical parameters. A variety of non-intrusive optical methods with high spatial and temporal resolution and probing techniques will be combined simultaneously to investigate the mutual interactions of the relevant parameters. The complexity of the measurement sequence will be gradually increased from laminar to turbulent flows and single particles to particle clouds. The sequence includes single particle combustion in laminar flows, group combustion in laminar flows, single particle combustion in turbulent flows and finally group combustion in turbulent flows. The aim is to understand the coupling of the individual phenomena like fuel particle characteristics, surrounding atmosphere and flow field and to derive appropriate models.
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A bond represent a long-term debt contract between a borrower and lender. The terms of this contract include the face value (the amount borrowed per bond issued) F, a rate of (annual or semi-annual) interest r, and the maturity (the date when the face amount must be repaid) N. The coupon of the bond R represents the periodic dollar amount of interest paid to the lender/owner of the bond over the life of that bond. This coupon amount is calculated simply by taking the product of the face value and rate of interest: R = (F) x (r) The price (or present value) a bond with coupon 'R' and a face value of 'F' at the end of 30 years is defined by the following formula: Pbond = PVbond = Σ[t=1,30] Rt(1+r)-t + F(1+r)-30 or using the formula for the sum of a geometric series: = (R/r)[1 - (1+r)-30] + F(1+r)-30 If the rate of discount 'r' is the same as the printed interest rate on the bond (so that R/r = F) then the above expression reduced to: Pbond = F As 'N' approaches infinity, (the Bond never matures) for any rate of discount this expression reduces to: which is known as the present value of a perpetuity and provides a simple formula for understanding the relationship between asset prices 'P' and asset yields 'Ψ' (or interest rates). Ψ = R / Pbonds The coupon payment and face value are fixed by contract over the life of the bond. If market interest rates are the same as the printed rate of interest on the bond, then the price (present value) of that bond is the same as its face value-- the bond sells at par-value. If market interest rates have risen, prior to the sale of the bond, such that investors can receive higher yields on competing investments; then, the market price of the bond will be less than its face value. The bond will sell at a discount. If the opposite is true such that market rates have fallen, then the bond will sell at a premium -- the market price will exceed its face value. Bond prices move in the opposite direction of market interest rates. You can practice with the model below: Activity in secondary markets often reflects changes in the economic environment where buying and selling activity is driven by changes in inflationary expectations, changing attitudes towards (credit and interest rate) risk, and changes in perceived uncertainty about the future. For example, suppose that information becomes available such that investors revise their inflationary expectations upward. Given that inflation lowers the real rate of return received by lenders (or those holding bonds and other securities), these individuals will begin to sell existing bonds in the secondary market. This selling creates a surplus of bonds being offered such that bond prices must fall to induce potential buyers to accept these securities in an accelerating inflationary environment. With this decline in bond prices, secondary bond yields increase: R / Pbonds ↓ = Ψ ↑ When yields rise, investors have the option of buying existing bonds in the secondary bond market or new bonds in the primary market. In order for these new bonds to be competitive with existing bonds, a higher rate of interest must be offered. This higher rate of (nominal) interest will reflect the upward revision of expected inflation. Secondary markets also facilitate portfolio adjustments in reaction to a changing economic environment or changes in individual preferences for risk. For example given two different assets one being higher risk (a BBB rated 5 year corporate bond) and the other no risk (i.e., a Treasury Note), we would expect that: ΨCorporate-BBB > ΨT-Note such that ρ = (ΨCorp.-BBB - ΨT-Note) If for some reason the perceived risk of holding debt instruments were to increase, we would expect to observe a flight to quality – a selling the corporate bonds and buying of Treasury instruments. Increased selling will drive the price of Corporate bonds down and buying activity will drive the price of Treasury Notes up or: PCorporate-BBB ↓, ΨCorporate-BBB ↑ and PT-note↑, ΨT-note↓ ΨCorporate-BBB - (ΨT-note) ↑ -- ρ ↑ Common stock represent ownership (equity) shares in publicly-held corporations. These rights of ownership often include a share in the profits (earnings) of that corporation. However, these earnings may be used either as a source of internal financing , known as retained earnings, or paid out to the owners as dividends. The value of the corporation is based on these earnings 'Et whether they are paid out or not. Pshare = ΣEt/(1 + r) Much is made of the price/earnings (PE) ratio of different common stocks with a low PE being often preferred to a high PE for a given stock. This ratio is often used as a benchmark to determine if that corporation is overvalued (too high) or undervalued(too low)by the stock market based on its current trading price. This ratio is nothing more than the reciprocal of a simple yield calculation based on the present-value of a perpetuity formula: Passet = (R/r) Ψasset = R/Passet Ψstock = Earnings/Pshare The earnings-over-price ratio is often in percentage form and by taking the reciprocal we define an integer expression that is often easier for use in making comparisons among different stocks. However, for purposes of evaluation, we can use the reciprocal of the PE and compare with investments of equivalent risk and maturity or against the yields on perhaps safer marketable assets. What is unique about equity instruments is that their value often is based not just on the periodic return (earnings in this case) but also the expected rate of growth for the corresponding corporation. The rate of return on common stock is often (usually for well-established mature corporations) calculated by the following formula: Ψ = E/Pshare + E[g] where 'Ψ' is the rate of return, 'E' represents annual earnings (or dividend), 'P' is the purchase price of a share of the stock, and E[g] is the expected growth rate in future dividends. Given an annual dividend of $1.00, a purchase price of $30.00 per share, and an expected growth rate of 5%; the rate of return would be: Ψ = ($1.00/$30.00) + .05 = .0333 + .05 = 8.33% This formula can also be used to determine the appropriate price to be paid per share of stock given expected growth rates in the annual dividend and some measure of the rate of return 'r*' based on similar investments. Solving for 'P', we have: Pshare = E/(r* - g) or given annual earnings of per share of $2.00, an expected (or required) rate of return of 8%, and an expected growth rate in future dividends for that company of 3% per year; we can calculate purchase price as: P = $2.00 / (0.08 -0.03) = $40.00 Quite often the explanation for the existence of both buyers and sellers of the same shares of stock is that buyers expect higher growth rates in future dividends relative to the expectations of sellers. Most Treasury bills and/or commercial paper (due to their short maturity -- 1 year or less) are discounted at the time of sale rather than pay some coupon payment over the holding period. This discount is calculated as follows: Discount = (F) x (r) x [(d)/ 365] where F is the face value (the amount borrowed or principal), 'd' is the days to maturity, and r is the market interest rate. For example, if a business needs to borrow roughly $1,000,000 for six months (182 days) to finance seasonal inventory needs, and current market rates are 10% then the amount of the discount would be: ($1,000,000) x (0.10) x (182/365) = $49,683 thus the actual amount borrowed by that business firm is: $1,000,000 - $49,683 = $950,137 However the full $1,000,000 is repaid at the maturity date. The rate of return (the yield) on this short-term debt instrument is equal to the amount of the discount divided by the amount borrowed or: $49,683 / $950,137 = Ψ = 5.23% semiannually or an effective rate of: (1.0523)2 - 1 = 10.7% annually Trading of money market instruments of particular face value ‘F’ is based on prices offered for these instruments in secondary markets or via auction in primary markets. The yield is then computed as follows: Ψdiscount = (F - Poffered)/Poffered = (F / Poffered) - 1such that as, Poffered ↑, Ψdiscount ↓ Since both stocks and bonds are marketable securities, the potential exists for changes in market price which may translate into capital gains or perhaps capital losses. A capital gain occurs when the selling price of a security 'Ps' exceeds the purchase price 'Pp'. If the selling price is less than the purchase price then the owner will incur a capital loss. Capital gains and losses can either enhance or reduce the normal rate of return on a given security. For this reason, acquisition of these securities are often based on expectations of future capital gains in addition to the normal rate of return. This overall yield or expected total rate of return 'E[TRR]' defined as follows: E[TRR] = rn + (E[Ps]- Pp)/Pp where 'rn' represents the normal rate of return ( current yield -- R / Pp) on the security and 'E[Ps]' represents the expected selling price of the security at some point in the future. Expectations about the selling price (E[Ps]) depend on expected changes in market interest rates (such that these prices and interest rates will move in opposite directions), and/or expected rates of growth in earnings (in the case of equities). Lower market interest rates or higher rates of growth can lead to capital gains on the sale of these assets such that the ETRR is greater than the current yield. If market interest rates are expected to increase or growth rates in earnings are revised downwards, then these asset may sell a price below the price paid and thus a capital loss results. In this case the ETRR may be less than the current yield and, in the case of an extreme increase in interest rates, be negative if with a significant decline in the selling price (the capital oss more than offsets the normal yield). In situations where investors expect the total rate of return to be negative on a financial asset, cash will present a suitable alternative given that: TRRcash = 0 Thus solid reasons may exist for holding cash in a portfolio of financial assets even though cash does not pay any type of periodic return. In the expectation of capital losses on marketable securities, principal may be preserved by holding cash.
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10 Lug How do i connect audio on zoom – How do i connect audio on zoom Ensure this is checked, to confirm that you are transmitting stereo sound to the people in your digital event. So feel free to experiment. Zoom call availability extends across multiple user devices in the office and at home, including laptops, smart phones and mobile devices, desk phones, soft phones, video clients, USB, and audio devices and much more. Make sure that the audio is connected to your mobile device. With the Zoom gallery view, you can quickly get an overview and see all participants even in large Zoom meetings. Don’t touch this if you’re not sure of what you are doing. Why Audio NOT working on Android or iOS devices for Zoom App – Zoom Guide Speakers built into the smartphone have been disabled in the app. Zoom: Joining Meeting Audio by Phone : Remote Learning and Work. If you take part in lots of different video conferences, you might like to use a different name for each one. For video chats with friends or relatives, a nickname or first name is sufficient. For official meetings, however, using your full name looks more professional. Recording a Zoom meeting is especially important for users who cannot attend a meeting, conference, or workshop for whatever reason. It is also practical to record Zoom meetings so you can post them online later as informational material or so you can rewatch an interview. We explain how to record meetings on Zoom here. Special WordPress blog themes let you create interesting and visually stunning online logs You can turn off comments for individual pages or posts or for your entire website. Keep reading to find out how Our WordPress guide will guide you step-by-step through the website making process Why wait? Grab your favorite domain name today! Matching email. SSL certificate. Save now. Zoom meeting has no sound? This could be the reason Video conferences have many advantages. Typical error sources include: Other participants have muted their microphone, speakers, or headphones. Incorrect audio settings or recording devices have been selected. Audio scripts are blocked by temporary data in the browser cache. Speakers built into the smartphone have been disabled in the app. Step 1 : Log in to your Zoom account by entering your user data in the Zoom client. Step 4: Here you will find a whole list of audio options. Test the function of your speakers and check whether the correct speaker is selected. Check the functionality of your microphone. Enable automatic audio connection via computer to give Zoom access to your computer audio when you enter a meeting. In this prompt window, you can also perform an audio test and enable automatic connection to computer audio. With computer audio connection disabled, Zoom will ask for speaker and microphone access before you enter each meeting. However, this could be the cause of the Zoom audio not working so remember to turn the microphone back on when needed. Zoom: No sound — how to solve the problem When it comes to small meetings consisting of two or three people, first ask the question: Have the other participants muted their own microphones or speakers? Test audio playback and recording devices in a meeting During a meeting, test your audio devices in the audio settings. Click on the arrow next to the microphone icon to open the audio settings and test your audio devices. Clear browser cache Too much temporary data in the browser cache can cause blocked audio scripts on Zoom in rare cases. Using the Zoom mobile app, click here to follow these steps in order to troubleshoot any issues you may be experiencing with your microphone:. The host might have muted you when you entered the meeting, if you are still muted. You can ask the host to unmute you by sending him a chat message. Make sure that the audio is connected to your mobile device. There is an icon that says Join Audio in the meeting controls. It can be clicked on and you will be able to choose Call Over Internet. In the event that you are prompted to allow Zoom access to your microphone, please do so.
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The state’s Unborn Child Dignity Act goes into full effect in February. “This law requires all embryonic and fetal tissue from a procedural abortion be cremated or interred, imposing severe burdens on patients and stigmatizing abortion even further,” the ACLU said in a press statement. The ACLU and abortion vendors, including Planned Parenthood, argue that properly disposing of an aborted baby is too costly and thus burdens a woman’s ability to get an abortion. The request for a preliminary injunction says that abortionists would have to make great effort to comply with the new law. The legislation, Senate Bill 27, “imposes extremely onerous provisions that require a sea change in how Plaintiffs dispose of embryonic and fetal tissue after a procedural abortion (sometimes called a surgical abortion),” the ACLU said. “Despite Plaintiffs having consistently and scrupulously followed the applicable regulations to dispose of infectious waste, which have been in place for years, SB27 would require all such tissue to be either cremated or interred (buried).” The ACLU said the new law “further stigmatize[s] abortion and severely burden[s] patients who seek this care” and will lead to “steep cost increases.” Currently, abortion facilities incinerate the aborted babies. Because of other Ohio laws limiting chemical abortions, SB 27’s implementation will “result in an effective total ban on abortion from 10 weeks of pregnancy until about 13 weeks of pregnancy,” the ACLU said. Ohio Right to Life (ORTL) said the law is about providing a “proper burial” for the human child and respecting their dignity. “SB 27 simply dignifies the life of a child who died because of an abortion and provides a proper burial for that child,” ORTL president Mike Gonidakis told The Columbus Dispatch. “The ACLU will do everything in its power to sterilize abortion and attempt to hide the fact that a successful abortion leads to the death of an innocent child.” “Planned Parenthood would rather have all aborted babies carted off to landfills in metal containers,” the ORTL president said. “The inhumanity of the ACLU and Planned Parenthood knows no boundaries. Ohio Right to Life is confident that this compassionate law will withstand court scrutiny.” The Indiana law, first signed in 2016, could have been helpful in preventing an Indiana abortionist from storing thousands of aborted babies in his garage in Crete Township, Illinois, just over the border from the Hoosier state. The wife of deceased abortionist Ulrich Klopfer made the discovery in September 2019 and alerted law enforcement.
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Twelve police officers who were at the centre of allegations of racism arising from a BBC documentary at a police training college in Cheshire are to face disciplinary procedures. The Independent Police Complaints Commission (IPCC) has decided that the police officers should be disciplined as a result of the investigation arising from the Secret Policeman television programme. Four trainers, including three who served at Bruche Training Centre, will receive written warnings. An additional seven constables and a sergeant will receive formal advice from a senior police officer. The IPCC has agreed that six of the officers must undergo diversity training and three of the trainers be removed from such work. Ten other officers resigned at the time of the broadcast in 2003. IPCC commissioner Nicola Williams supervised the inquiry. She said that a very thorough inquiry had been carried out by Greater Manchester Police in which 100 statements were taken and over 1,200 documents and exhibits obtained. “It is vital that the police service can permanently improve recruit training and ensure that each and every police officer supports the need to treat everybody fairly regardless of their race, religion or colour, she said.” The IPCC has recommended that: - A consultation process between the Home Office and police staff associations should be set up to consider improving the speed of disciplinary procedures in cases of gross misconduct, so that officers can face instant dismissal in cases where there is compelling evidence - A similar consultation process should be undertaken for trainee police officers, with a view to developing national regulations for trainees similar to those in place in Northern Ireland, where officers only hold the office of constable after a prescribed period of training - A national review be undertaken of the recruitment process to develop methods of identifying personality traits that are unacceptable in police officers. The feasibility of having an independent person on every recruiting panel for trainers must be considered - Centrex, the Central Police Training and Development Authority, should undertake a national review of the delivery of race and diversity training and develop a method of evaluating the effectiveness of such training once it has been delivered. A Commission for Racial Equality (CRE) investigation into the recruitment, training and monitoring of police officers’ conduct and the management of their behaviour set up after the broadcast is due to be published next week.
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In the year 2020, Tenney-Lapham is a diverse residential neighborhood on Madison’s Isthmus. As an older neighborhood with mature housing stock, it offers Madison good-quality affordable housing. The neighborhood also has significant historic structures both in and out of the Fourth Lake Ridge and Sherman Avenue Historic Districts. The area has a good mix of owner-occupied and rental housing. In fact, many two and three unit structures are both – with the owner occupying one unit and renting out the others. Between 2008 and 2020, significant new development occurred in the neighborhood along East Washington Avenue between Blair Street and the river and along the Yahara River Parkway. Across the river, a multi-modal transit hub linking commuter rail, streetcars, airport shuttles, buses and a park-and-ride offers local residents many transit options. In previous decades, the neighborhood had a large population of university students. However in the late 1990’s and early 2000’s, the construction of multi-story, high-density student apartment buildings closer to campus caused a sizeable shift in student rental patterns away from this near eastside neighborhood. In 2020, Tenney-Lapham is more likely to provide affordable, workforce housing along quiet streets suitable for raising families. This transformation was fostered by important changes in City transportation policy and zoning, and also through more frequent building inspection and incentives for conversion of properties from absentee landlord to owner-occupancy. In transportation, a significant step was the return of Johnson and Gorham Streets to two-way between Wisconsin Avenue and Baldwin Street. A new zoning ordinance, local landmark designation of the Fourth Lake Ridge and Sherman Avenue Districts, and a new conservation district ordinance maintained most of the older neighborhood as one, two and three unit structures. As the rental vacancy rate rose, the City and local financial institutions offered incentives for properties to be acquired by owner-occupants, including owner-occupied two and three units. Other multiple unit structures converted to condominiums. These changes provided many opportunities for members of Madison’s workforce to obtain affordable housing in a safe, convenient, residential area that is within the City limits. The proximity of this neighborhood to downtown and the campus has made it an ideal area for the City to introduce and foster alternatives to automobile transportation. Further reducing the pressure of automobile commuting through this neighborhood was the development of a park-and-ride transit hub just east of the Yahara River in the area bounded by East Washington Avenue, First and Johnson Streets. This location provided a natural hub for receiving arterial traffic from East Washington Avenue, Fordem and Pennsylvania Avenues. The existing rail infrastructure in this area enabled the return of passenger rail. The transit hub is more than just a parking lot and commuter/light rail station. It also includes recreational green space as part of the Yahara River Parkway and offers restaurants and retail shops enabling commuters to take care of daily errands as they transition among rail, bus, cars and bikes. Last but not least, Tenney-Lapham also has a traditional neighborhood business district along East Johnson near Paterson Street. With the influx of more families and long-term residents, the business district has thrived and expanded along the 700, 800 and 900 blocks of East Johnson Street. The availability of shopping within walking distance of home and via alternative transportation, such as the Isthmus-circulating shuttles and streetcars has made neighborhood living much more viable. For all its residents, but most particularly for people with fixed incomes, disabilities, or working at lower wages, Tenney-Lapham offers a neighborhood where it is possible to be a no-car or one-car household without being culturally, economically or socially isolated from enjoying the full life of the City.
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From football matches to festivals, concerts to car races, there are thousands of spectator events every year that require stewards. Stewards are responsible for ensuring the safety of spectators and ensuring that an event runs smoothly. The content of this course perfectly matches the knowledge components syllabus of the Highfield Level 2 Award in Understanding Stewarding at Spectator Events (RQF). The course may also be used to underpin the knowledge required of the level 2 NVQ certificate in spectator safety qualification. - Prepare for spectator events - Control the entry, exit and movement of people at spectator events - Monitoring spectators and dealing with crowd problems - Dealing with accidents and emergencies Who is it aimed at? The course is useful for anyone looking to work as a steward at spectator events. It may be particularly useful for learners looking to gain a recognised level 2 qualification in spectator safety. No prior knowledge needed 6 – 7 hours How It Works Our e-learning is available to use on multiple platforms such as tablets, PCs and laptops. All you need is an internet connection. Learners simply log on to the Highfield Learner Management System (LMS) and work their way through the course, along with the scenarios that provide them with real-life context. Learners are assessed at the end of the course by multiple-choice questions. Learners will receive a Highfield e-learning completion certificate, which is downloadable upon successfully finishing the course. Why Choose Highfield E-learning? We make the most complex of subjects easier to digest through media and content-rich exercises that motivate and engage learners. All of our e-learning uses interactive exercises and gaming combined with media-rich content, interactive scenarios, and relevant photography and illustrations. Content is provided by industry-leading experts. What that means for your learners is stimulating and engaging content they’ll respond to and, most importantly, remember. Key elements of our e-learning courses are: - interactive exercises/gaming - media-rich content - interactive 3D scenarios - content provided by market leading experts - relevant photography and illustrations - multi-generational content and style Try Our Courses We’re happy to let our course speak for itself. Click on ‘Try our Courses’ you will then be asked to enter your details. Once you have entered your details you will be re-directed to a demo account.
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The Kiwi comes from Aotearoa New Zealand and its succulent green or yellow flesh is delicious on top of a pavlova. No! Wait! That’s a kiwifruit, not a mammal, real or honorary. They originally came from China in the late 19th or early 20th century and were known as Chinese gooseberries until it became an export commodity, at which time the name proved to something of a hindrance. Having both “Chinese” and “berry” in the name proved to be too much for the sensibilities of Americans at the time so a new name was coined. Sorry. The Kiwi is a two legged mammal that… Umm. I thought Kiwis were real mammals, not honorary ones. Now you’re referring to human beings who consider Aotearoa to be their home. Yes they are real mammals. I’m referring to another 2 legged creature. Oh! You mean the bird? Precisely. One of the peculiarities of Aotearoa New Zealand is that prior to the arrival of humans around 800 years ago, the only terrestrial mammals inhabiting these islands were three species of bats – flying mammals. On the other hand, there was a vast range of flightless bird species. Kind of back to front compared to the rest of the world Back to front? Flying mammals and flightless birds. I suppose that’s one way of looking at it. But back to the kiwi. It’s often referred to as an honorary mammal because it exhibits some characteristics that are very mammal-like and rarely, if ever, seen in birds. Here’s a few examples: The power of flight is very costly in terms of energy requirements and birds have made a number of evolutionary adaptations in order to minimise this cost. Think weight reduction. Bone structure: Birds typically have lightweight bones filled with air sacs to reduce weight. Flightless birds may have slightly denser bone formation but still retain air sacs. The kiwi on the other hand, has heavy marrow-filled bones just like mammals. Reproduction: Female birds typically have a single ovary, again an adaptation to reduce weight. Kiwi have two ovaries, and just like mammals, ovulation occurs alternately in each. Leg muscles: Birds have considerably less leg muscle mass compared to mammals of equivalent size. Again an adaptation to reduce weight. However, the kiwi has gone to the other extreme. The legs make up one third of their total weight. To put that into perspective, a typical kiwi is about the same size as a fowl (chicken) and weighs in at slightly over 3 Kg (around 7 lb). If you were able to buy kiwi meat from the supermarket, a single leg would weight around 600 grams or 1.3 lb. That’s some leg! Kiwi put those legs to good use. Adult kiwi can easily outrun humans, and their legs and sharp claws can be used to fend off introduced predators such as cats, stoats, rats and possums. However, dogs can wipe out entire kiwi population in single area almost overnight. Skin: Kiwi have tough leathery skin that is more mammal like than bird like. Vision: Birds rely on good eyesight for survival. In the case of nocturnal birds, eyes become oversized to ensure adequate light reaches the retina. However, Kiwi imitate many mammals that occupy a similar ecological niche in other parts of the world. Eyes are small and eyesight is poor. Kiwi are very long sighted. So much so that even objects on the horizon have a focal point well behind the eye. Kiwi have almost no binocular vision (where the visual fields of both eyes overlap). They cannot even see their own beak! Rare for birds, they cannot see colour. Sense of smell: On the other hand, their sense of smell is highly developed. In the bird world, only the condor has a better sense of smell. Birds typically have a bony ridge between the eye sockets. In the kiwi, this space is occupied by a nasal cavity, just like mammals. Birds typically have their nostrils at the base of their beak. Not so the kiwi. It’s the only bird with nostrils at the tip of the beak. This is used to help locate underground grubs. Sense of touch: The nostrils are surrounded with mechanoreceptors (pressure-sensitive receptors). It was once thought that kiwi located prey entirely by smell, but new research indicates that the mechanoreceptors might allow the kiwi to detect prey up to 10 cm (4″) underground. Hearing: Few birds have highly developed sense of hearing. Kiwis are an exception. As with the areas of brain related to the sense of smell, that area related to hearing is larger in size and more complex than other birds of similar size. The external ear openings are large and can easily be seen Whiskers: Cats and many nocturnal mammals, have whiskers to aid in the detection of objects in close proximity in the dark. Kiwi have whiskers on their face and base of their beak that serve the purpose. Burrows: Like badgers, kiwi build burrows where they hide out when not foraging and for nesting. Kiwi sleep standing up. No preen gland or tail: Other birds have a preen gland near the tail that supplies oil used to keep feathers weatherproof, waterproof and in good condition. The kiwi has neither. No wings: Well not quite, even though the genus name Apteryx means wingless. Flightless birds typically have rudimentary wings equipped with flight feathers. The wings retain some purpose such as for display in attracting a mate or fending off opponents, to assist in balance, and to allow safe descents from a height. Not so the kiwi. A human in freefall with outstretched arms has greater powers of flight than a kiwi. It’s vestigial wings are barely 3 cm (about an inch) long, are not feathered and remain hidden under the kiwi’s plumage. Hair-like plumage: Kiwi look soft and fluffy. Most birds have feathers equipped with hooks and barbs that keep the feathers in the neatly arranged vanes. Kiwi do not. The feathers hang loose, and in appearance look like fluffy hair or fur. Body temperature: Birds typically have a body temperature of between 39ºC – 42ºC. Kiwi have a body temperature similar to mammals: 37ºC – 38ºC. Other facts about kiwi. Species: Up until the 1980s it was thought that there were only 3 species of kiwi. However, with the aid of DNA technology, it’s now known that there’s at least 5 species. What is unusual is the fact that there is very little difference in physical characteristics between species and DNA testing is necessary to identify them. The mechanism whereby five distinct species with almost identical characteristics could evolve in a relatively small geographical area is not fully understood, but one theory is that New Zealand was repeatedly fragmented by glaciers during Middle and Late Pleistocene. Fragments remained isolated long enough for speciation to occur but there was nothing to drive differentiation. It’s now known that there were many more species prior to the arrival of humans. Huge egg: We Kiwi like to claim that the kiwi produces the largest egg in comparison to its body size, but the claim can also be made of the bee hummingbird. Both species produce an egg that’s up to 25% of the weight of the mother. A kiwi lays an egg that is about six times heavier than a chicken egg. Birds’ eggs are typically 35% – 40% yolk. Kiwi eggs are 65% yolk. In two kiwi species, incubation is shared equally by both parents, but in the other species the female takes no part in the incubation. It’s a male only task. Given the size of the egg she has to lay, I’m surprised any female kiwi would want to have anything to do with it. Mate for life: For the most part Kiwi form lifelong monogamous partnerships. I say for the most part because while males always remain faithful, female kiwi are known to abandon their mate if she comes across a male she finds more attractive. Declining numbers: Kiwi take around five years to reach sexual maturity, and in most species the female produces only one or two eggs each year. Mainly due to mammalian predation, only about 5% of kiwi chicks survive into adulthood. It needs to be around 20% to maintain the population. In areas with extensive (and expensive) predator control kiwi populations can double approximately every ten years. Nationwide, the kiwi population is declining at around 2% per year.
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Just called to check on my mother and one of the things I made sure I mention is the newly approved law — Republic Act No. 10361 or popularly known as the Kasambahay Law. Since we left home years ago to live our own lives, our parents, specifically our mother, got people to help around. Our house also became the home of anyone whom my mother thought needs shelter while at the same time could extend hands in doing the daily chores. Whether they’re related to us by consanguinity or just perfect strangers, my mother accommodated them. It’s the trait Ithink I would never have as I have trust issues with maids — thanks but no thanks to the different news about househelpers who sooner or later turned out to be more of a liability to their masters or employers. Employers, yes that’s the more appropriate word now that the Kasambahay bill became a law on January 18, 2013. While that technically eliminates the seemingly discriminating (or oppressive) master-servant term, this law which is, to quote its title, an act instituting policies for the protection and welfare of domestic workers, obligates the employers to give their househelpers minimum wage and social benefits provided under existing laws such as Philhealth, Social Security System (SSS), and Pag-Ibig fund. Admittedly, the law that I once perceived as just and humane, is now something I should be worried of due to several reasons which the other ’employers’ around the nation also share based on what I have heard from TV Patrol. Firstly, all the social benefits would have to be paid regularly by the employer. And the fact that the government institutions wherein payments are to be made aren’t located in one place is a problem by itself. I can’t imagine my mother, now in her 60s, going from one place to another, not to mention endure long lines, just to remit the social benefits of her househelpers. Next item to consider is the stipulation that the househelpers should be given basic education. Even though my mother has been good enough to offer this to one of her helpers ahead of the Kasambahay Law, this still leaves the question: what if everyone goes out to study? Doesn’t this defeat the very purpose why one got help because there’s a need to have someone in the house do the chores during most times of the day? But not all aspect of this law are questionable. Things such as the need to have decent sleeping quarters and providing basic necessities are no-brainers and I can assure that whoever stays in my parents house will have these. The implementing rules and regulations (IRR) for the Kasambahay Law is still not out so I guess I have to wait before I call my mother again to remind her that she follows it as the last thing I’d like to hear is that there’s a picket line outside our small house demanding for an increase in wage and benefits. Ti abi. There was once a time when the maids demand just to have access to TV. Now, the WI-FI is starting to become a must have. Mood: 2/10 Honks! (Wifey’s out. Just me and our master at home. Master, aka Marcus, still sleeping. I’m waiting for orders.)
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Keith Small wrote that any religion professing to be the sole foundation of truth should never shy away from any form of scrutiny. He wrote; “Many people of all faiths and no faith have come to realize that religious tradition cannot be followed blindly. If a religion is to commend itself in this age, it must be open to the hardest and best questions put to it. We no longer live in a world where religious communities can keep themselves aloof from the criticism and scrutiny of others who don’t share their beliefs and values.” When considering the most revered book of Islam, I want to look at three points that are essential when considering its history. In part one of this article, I will show that there is a lot of speculation concerning the content of the book’s origins. Tales of the Ancients. It is no secret that Islam’s most revered book contains narratives that bare a strange resemblance to some myths that were penned before the origins of the Qur’an. Surah Al Furqan (25.5) records an explicit accusation that Muhammad repeated the ‘tales of the ancients’ (6.25, 8.31, 16.24, 23.83, 27.68, 46.17, 68.15, 83.13). “And they say: “Tales of the ancients, which he has caused to be written and they are dictated before him morning and evening.” The Sahih International translation says; “And they say, “Legends of the former peoples which he has written down, and they are dictated to him morning and afternoon.” Historically Muhammad was accused of repeating and incorporating previous odes from before the revelation of the Qur’an, including it as a sacred revelation. Missionary Rev. W. T. St. Clair- Tisdall, tracks foreign elements within the Qur’an from Jewish folklore, Gnostic sources, as well as Zoroastrian and Buddhist tales. These sources were known to be false theologically and historically but were effortlessly validated and included in the Qur’anic text as divine revelation. Tisdall at the turn of the 1900s laments that; “the influence of true and genuine Christian teaching upon the Quran and upon Islam in general has been very slight indeed, while on the other hand apocryphal traditions and in certain respects heretical doctrines have a claim to be considered as forming one of the original sources of Muhammadan faith.” There are numerous examples of these legends and folk stories included in the Qur’an, but for the sake of time I will give just two examples. In Surah Al-Anbiya (21.51-70), the story relates how Abraham frowns upon his Father idolatry smashing the Idols he venerated. This story is found in the ‘Midrash B’reish it Rabba’ (38.12-13) where it is attributed to a Jewish Rabbi, Hiyya, who devised the story to show the perils of idolatry. Rabbi Hiyya’s tale was discussed by early church-Father Jerome (347-419/420) and was also mentioned in the Jewish ‘Book of Jubilees, ‘ which dates to the 2nd century and the Babylonian Talmud. In another part of the Qur’an, we find a story relating to Jesus speaking supernaturally from the cradle. The source of this story comes directly from the ‘Arabic Gospel of the infancy of the Saviour. Surah Maryam (19.29-31) and Surah Ali’ Imran (3.46), includes this narrative as a historical certainty. At the same time, we know it is merely a deduction from early gnostic sources influenced by an early pseudo-Christianity. Peter Townsend writes; “Muhammad was clearly unaware of the actual origins of this story, i.e. that it does not appear in the Gospels, and is therefore willing to grant it exalted status as the Word of Allah.” Some Muslims attempt to say that these early renditions were deductions from a prior revealed text that could have contained the original words of Allah, but there is no historical account for this claim to be validated. Rev. W. T. St. Clair-Tisdall, therefore, concludes that when we look at the source of Muhammad’s revelation; “we find that the first “source” of the Koran and tradition consisted of the notion, customs, and religious beliefs, existing around Muhammad.” The author of the Qur’an clearly cannot tell fact from fiction. And these stories are counted as fact. Previous Revelations and the preaching of past Prophets. It is no secret that Muhammad held the previously revealed texts in high regard, even though there is very little evidence that he read any of them. Sidney Griffith argues that neither the Jewish nor the Christian books were available in Arabic at the time of the Qur’an ‘s origins. It does not seem like Muhammad had an intimate knowledge of what was contained within these texts. Three earlier Scriptures are mentioned in the Qur’an, the Tawrāt (Arabic: توراة), the Injl (Arabic: إنجيل), and the Zabūr (Arabic: زَبُورُ) which corresponds with the Judeo-Christian books, the Torah, the Gospel, and the Psalms. Gordon Nickel writes that; “None of the verses in the Qur’an that explicitly mention the names Tawrāt, Injíl, or Zabūr makes a negative statement about these earlier Scriptures. There is no hint in any of these verses that the earlier scriptures exist in a corrupt or falsified state-which is the accusation of Muslim polemicists against the Bible.” Muhammad never seemed to bother Christians or Jews about the content of their books and even affirmed the authority of their texts until he realized that the very documents he affirmed contradicted his ‘new’ revelation. Even then, he still refers to the meaning being supposedly mistranslated but in no way hints to the fact that the manuscripts were distorted. Gabriel Said Reynolds writes; “Early Islam was faced with a similar choice in regard to the Jewish and Christian Bible. Muslims, in theory, could have considered the Bible authoritative Scripture. There are some signs that the author of the Qur’an attributed such authority to the Bible. In one place the divine voice of the Qur’an commands its Prophet to confer with those “who read the Book” in times of doubt (Q 5:47)… in other passages (e.g., Q 2”42, 59, 79; 3:71, 187; 4:46; 5:13; 7:162), the Qur’an suggests that the Jews (especially) and the Christians (also) have misread scripture, have hidden passages, or have pretended that things which they themselves have fabricated are Scripture.” It is impossible to make any sense of the narratives of the Qur’an without referencing the Judeo-Christian Scriptures. The reader should note that the Qur’an is solely reliant on these previous Scriptures to give context to its own narrative. The Qur’an is therefore not only reliant on divine inspiration but equally dependent on these previous texts. The context of the Qur’an and traditions of the Prophet shows that Muhammad tried to collaborate his new revelations by leaning on the previously revealed Scriptures. Gabriel Said Reynolds writes; “the Qur’an’s author also played an active role in developing Biblical material. The Qur’an has not simply borrowed material from Jews and Christians. Instead, it has consciously reshaped Biblical material to advance its own religious claims.” It is generally assumed that Muhammad was mentioned in the Judeo-Christian Scriptures. Sura Al-A’raf (7) 157 notes, “Those who follow the Apostle, the unlettered Prophet, whom they find mentioned in their own (Scriptures), – in the Law and the Gospel…” Another passage in Sura As-Saf (61) 6 states plainly; “And remember Jesus, the son of Mary, said, ‘O children of Israel! I am the apostle of God (sent) to you, confirming the Law (which came) before me, and giving glad tidings of an Apostle to come after me, whose name shall be Ahmad.’” A note (416) from Yusuf Ali’s Translation of the Qur’an mentions this reality by stating: “… In the Old Testament as it now exists, Muhammad is foretold in Deut. 18:18… In the New Testament as it now exists, Muhammad is foretold in the Gospel of St. John 14:16, 15:26 and 16:7… The Greek word translated ‘Comforter’ is ‘Paracletos,’ which is an easy corruption from ‘Periclytos,’ which is almost a literal translation of ‘Muhammad’ or ‘Ahmad’. … Further, there were other Gospels that have perished, but of which traces still remain, which were even more specific in their reference to Muhammad…” Both Christians and Jews have refuted this notion entirely and have shown that Muhammad could not have been the one mentioned in both Deuteronomy and John’s Gospel. Moses spoke of the qualification for the Prophet to come in Deuteronomy 18, and this Prophet needed to come from amongst his Jewish brethren (v/18) for them (v/15) speaking in the name of Yahweh (v/20). Muhammad fulfilled none of these. We also find that Stephen unequivocally identifies this passage as foretelling Jesus and not Muhammad (Acts7:37). The previous Scriptures in no way affirm the Prophet of Islam to be evident in its pages. So, when the Qur’an says in Surah Al-Mu’Minum (23) 23 that; “We sent a long line of prophets for your instruction” which according to the Hadith is 124,000 ‘Nabi’s’ beginning with Adam and ending with Muhammad, the Judeo-Christian Scriptures are oblivious to the evidence of this that is supposedly so. Rev. Richard P. Bailey gives a chart that lists only about 133 from the Judeo-Christian Scriptures. Jesus makes it clear that all of the previous Scriptures speak about Him and not another Prophet to come. He declares in Luke 24; “25 He said to them, “How foolish you are, and how slow to believe all that the prophets have spoken! 26 Did not the Messiah have to suffer these things and then enter his glory?” 27 And beginning with Moses and all the Prophets, he explained to them what was said in all the Scriptures concerning himself… 44 He said to them, “This is what I told you while I was still with you: Everything must be fulfilled that is written about me in the Law of Moses, the Prophets and the Psalms.” Jesus claims that He is the central message of the whole sweep of the Old Testament. When Christ speaks to the religious Jews, he claims as Messiah that His presence should be central to the fulfilled expectation of the Old Testament Scriptures in John’s Gospel account (5:39). “You study the Scriptures diligently because you think that in them you have eternal life. These are the very Scriptures that testify about me, yet you refuse to come to me to have life.” In Matthew’s account (5:17) Jesus makes it clear. “Do not think that I have come to abolish the Law or the Prophets; I have not come to abolish them but to fulfill them. For truly I tell you until heaven and earth disappear, not the smallest letter, not the least stroke of a pen, will by any means disappear from the Law until everything is accomplished.” Even though Muhammad, the author of the Qur’an, and Muslims claim that he was foretold and expected in the previous revelations and the preaching of past Prophets, we struggle to find this to be so. From the beginning, Muhammad was accused of plagiarism and external natural influence on his revelations. In Surah Al-Nahl (16) 103-104 it says; “We know indeed that they say, “It is a man that teaches him.” The tongue of him they wickedly point to is notable foreign while this is Arabic pure and clear. Those who believe not in the Signs of Allah, Allah will not guide them and theirs will be a grievous Penalty.” (Yusef Ali’s translation) In Al-Kindy’s Apology, he relates a story that shows very clearly that Muhammad’s source of revelation could have been a Nestorian Monk, Sergius, who introduced Muhammad to some of the supposed revelations he received. Al-Kindy writes; “The disclosure may be bitter, but it will be wholesome in the end.” He then proceeds to give a lengthy account of the origin of the Coran.1 His story in short is this. “Sergius, a Nestorian monk, was excommunicated for a certain offence. To expiate it, he set out on a mission to Arabia, and reached Mecca, which he found inhabited by Jews and idolaters. There he met Mahomet, with whom he had intimate converse, and persuaded him, after being instructed in the faith of Nestorius, to abandon heathenism, and become his disciple.” The accusations of external influences upon the revelation of Muhammad seems to be numerous. The Sahih International translation says in Al Furqan (25) 4; “And those who disbelieve say, “This [Qur’an] is not except a falsehood he invented, and another people assisted him in it.” But they have committed an injustice and a lie.” There was not just an accusation of plagiarism but also the invention and incorporation of legends, fables, as well as simple myths. In Surah Al-An’am (6) 25 it states; “And among them are some who give ear to thee; but WE have put veils on their hearts, that they should not understand, and deafness in their ears. And even if they see every Sign, they would not believe therein, so much so that when they come to thee, disputing with thee, those who disbelieve say, `This is nothing but fables of the ancients.’” Numerous passages within the Qur’an shows quite clearly that everyone suspected these revelations to be tales of the ancients (8:31, 16:24, 46:17, 68:15, 83:13). Another passage, Surah Al-Furqan (25) 4-6, says that Muhammad was accused of being instructed ‘day and night’ about these tales from the past. It reads; “And those who disbelieve say, “This [Qur’an] is not except a falsehood he invented, and another people assisted him in it.” But they have committed an injustice and a lie. And they say, “Legends of the former peoples which he has written down, and they are dictated to him morning and afternoon.” The Study Qur’an notes that; “Some commentators name specific people who were learned in the Torah, but then became followers of the Prophet, and it was alleged that he took stories from them. Many commentators connect these verses with a certain Nadr ibn al-Harith of the Quraysh, a storyteller who would recite stories from Persian history and myth; the disbelievers would compare his stories with the Quran and announce in the Prophet’s presence that al-Harith’s stories were better.” Early sources account emphatically that Muhammad was thoroughly instructed by various individuals like non-Arab slaves, a Christian blacksmith , Jabr and Yasar, Suheib son of Sinan. Even further, we find that some individuals were transcribers that wrote down the revelations for Muhammad as if it was his own. Shahih Bukhari writes; “Narrated Anas: There was a Christian who embraced Islam and read Surat-al-Baqara and Al-Imran, and he used to write (the revelations) for the Prophet. Later on, he returned to Christianity again and he used to say: “Muhammad knows nothing but what I have written for him.” Waraqa Ibn Nawfal was named as one such individual that taught the Prophet of Islam. Narrated ‘Aisha: Volume 1, Book 1, Number 3 “Khadija then accompanied him to her cousin Waraqa bin Naufal bin Asad bin ‘Abdul ‘Uzza, who, during the pre-Islamic Period became a Christian and used to write the writing with Hebrew letters. He would write from the Gospel in Hebrew as much as Allah wished him to write. He was an old man and had lost his eyesight. Khadija said to Waraqa, “Listen to the story of your nephew, O my cousin!” Waraqa asked, “O my nephew! What have you seen?” Allah’s Apostle described whatever he had seen. Waraqa said, “This is the same one who keeps the secrets (angel Gabriel) whom Allah had sent to Moses. I wish I were young and could live up to the time when your people would turn you out.” Allah’s Apostle asked, “Will they drive me out?” Waraqa replied in the affirmative and said, “Anyone (man) who came with something similar to what you have brought was treated with hostility, and if I should remain alive till the day when you will be turned out then I would support you strongly.” But after a few days Waraqa died.” When we look at the plethora of accusations late Iranian Muslim scholar Ali Dashti wrote: “A process of this kind had begun in Mohammad’s mind during his childhood and had prompted him to meet and talk with Christian monks and priests on his Syrian journey instead of spending all his time on commercial business. On his way back, through the lands of Medyan and the Ad and Thamud, he had heard the legends of the local people. In Mecca itself, he had exchanges and visits with followers of the scriptural religions. He had sat for hours in Jabr’s shop near the hill of Marwa and had been in constant touch with Khadija’s cousin Waraqa b. Nawfal, who is said to have translated a part of the New Testament into Arabic. All these experiences are likely to have turned the ever-present disquiet in his inner mind into turmoil. There is a reference in the Qoran to Mohammad’s long and frequent talks with Jabr. The Qorayshites alleged that Mohammad had learned the words of the Qoran from Jabr, who was a foreigner… The biographies of the Prophet mention several other followers of the scriptures and possessors of knowledge with whom he exchanged visits before the start of his mission, e.g. Aesh, the sage of the Howayteb tribe, Salman ol-Farsi, and Belal the Abyssinian. Abu Bakr also had discussions with him at that time and agreed with him.” There is simply no doubt that Muhammad had some external influence apart from the Angel Jibreel (جبريل “Gabriel”) for his revelation. Muhammad deemed the ‘tales from the ancients’ to have some value, and these tales are therefore found in the Qur’anic text as inspired (waḫy). The Author of the Qur’an also approves the previous revelations, the Tawrāt (Arabic: توراة), the Injíl (Arabic: إنجيل), and the Zabūr (Arabic: زَبُورُ), to be inspired books that he attached to his own perceived revelation. Lastly, the author of the Qur’an also listens to the instructions given by people around his Prophet. Their opinions then find themselves collated within the central book of Islam. Holy Books have a History, Pg. iv. The Original Sources of The Quran, Society for the promotion of Christian Knowledge, London, Pg.210 – 211 1905. Read: https://www.answering-islam.org/Silas/borrowing.htm The Origins of the Quran, Pg.235. The Bible in Arabic, Pg.41-51. The Gentle Answer, Pg.23. The Qur’an and the Bible: Text and Commentary, Pg.1. Ibid, Pg.3. The Apology of Al Kindy, Pg.70. can be accessed here: https://www.answering-islam.org/Books/Al-Kindi/p070-071.htm The Study Quran, Pg.891. “traditions mention the names of several persons, one of whom (Jabar), according to the disbelievers of Makkah taught the Holy Prophet; however, one thing particularly noteworthy about all these persons is that they were non-Arab slaves. Whosoever he might be, the fact that he used to recite the Torah and the Gospel and had an acquaintance with the Holy Prophet, gave an opportunity to the disbelievers for spreading this false report that it was the particular slave who was the real author of the Holy Qur’an, but Muhammad (Allah’s peace be upon him) presented it as the Word of God.” Source: http://englishtafsir.com/Quran/16/index.html#sdfootnote107sym “a foreign (i.e., non-Arab) man who lived among them as the servant of some of the clans of Quraysh and who used to sell goods by As-Safa. Maybe the Messenger of Allah used to sit with him sometimes and talk to him a little, but he was a foreigner who did not know much Arabic, only enough simple phrases to answer questions when he had to.” Tafsir Ibn Kathir. Islamic Images and Ideas: Essays on Sacred Symbolism edited by John Andrew Morrow, Pg.252. 23 Years: A Study of the Prophetic Career of Mohammad, Pg.21- 22.
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Opinion: Half of Americans now aren’t sure their children will have a better life: poll This article was originally on a blog post platform and may be missing photos, graphics or links. See About archive blog posts. Naturally enough, politicians and journalists and political spectators watch an election season’s polls for the obvious insights they can offer into the electorate’s mood and balloting intentions. But amid all the fears and anger and uncertainty and disenchantment and disappointment and disillusionment washing across the country in these late election campaign days, there’s an ominous little discovery buried within a new Bloomberg News poll this morning. It has nothing to do with the Nov. 2 midterm elections. And everything to do with future ones. The survey finds that more than half of Americans are either not at all confident or just slightly so that their children will have a better life than they do as parents. Warranted or not, optimism and confidence in a better future for the next generation has been present throughout decades of modern American history. It fueled millions of 19th century immigrant dreams. It sustained parents through the Great Depression and the world war that followed. And fueled the optimistic baby boom that ensued after. It drove the postwar generation of simultaneous fulltime workers and parttime students. It tempered the ubiquitous anxiety of the long cold war. And the domestic violence, tumult and dissension of Vietnam. And the later inflation. And on and on. You just hang in and do your best and your kids will have it better than you do. Guaranteed. Even though you may not live to see all of their better future, you can count on it. And anything smacking of struggle now will surely pay off later for them because that’s the knd of country this is. But not now. Not, at least for half of those surveyed. Perhaps more. The president for his own purposes and perhaps beliefs says the worst is over from the recession that officially ended more than a year ago. But economic growth for the second quarter dipped to 1.7% from 3.7% in the first and 5% late last year. A bad third-quarter number is likely just before election day. And no sign of improvement beyond, despite collossal government stimulus spending. Unemployment is stuck at 9.6%, the 14th straight month it’s been above 9.5%, the longest such period since that Great Depression. Virtually everyone knows someone or several like themselves, not a spend-thrift but a regular person who’s unemployed now through no fault of their own with little prospects and maybe losing their home, perhaps unfairly by amazing screw-ups. And oblivious federal and state governments talk of budget deficits beyond mortal comprehension, exceeding the digits on anyone’s personal calculator. A year of college, long the presumed ticket to a successful life, can now cost what a starter home used to cost with a 30-year mortgage. To survive, Bloomberg finds, 44% have cut household expenses like cable TV. Almost half have started using coupons, changed their grocery-buying habits; 54% postponed a major purchase. And 85% report some steps to cut spending and save money, pulling in. Not the signs of confidence in the future, for themselves, let alone their offspring. For short-term gain politicians, who are just as puzzled and frightened for their own future as everyone else, promise progress and victories they know are impossible, the same quick-profit strategy that got Wall Street in such ominous trouble two years ago. The pols run around rhetorically pointing fingers and calling names, arguing over TV networks, using car crash analogies and professing offense at the drop of certain words. Almost 60% of the country sees the federal government as too intrusive and powerful, up 8 points from just last year. And, by the way, somebody else should pay a larger share of government costs. Now, just wait for the president’s December deficit commission report perfectly-timed to depress the holidays. Here come more taxes and there goes some part of Social Security for some somebodies. More than 55% of those under age 65 tell Bloomberg they have no confidence they’ll receive the same Social Security or Medicare benefits as today’s seniors. So, no wonder they doubt their children’s bright future once believed so inevitable. The Nov. 2 balloting, already underway in early voting across the land, could provide some cartharsis, let off some of the angry steam. Things could improve somewhat over time. Or they could all just continue to fester and blow up in some incumbents’ faces someday. What’s different about the 2010 election lead-up is the common use now of the conditional tense. Things could get better. In the past, better was a self-fulfilling given. -- Andrew Malcolm One thing you can count on, however: Click here for tax-free Twitter alerts of each new Ticket item. Or follow us @latimestot. Our Facebook Like page is over here. And, btw, we’re available on Kindle now. ReTweet this item to your Twitter or Facebook followers with the buttons below.
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Kaizen events are an integral part of the continuous improvement culture. The success of those events depends on many factors, such as the characteristics of the kaizen facilitator. This person is responsible for leading the event, among other things. Experience leading events and continuous improvement knowledge are not the only characteristics that a facilitator needs. What are the characteristics of a kaizen facilitator? Characteristics of a kaizen facilitator Whether you are looking to hire or contract, the following are most haves’ characteristics. The facilitator must be courageous. In other words, a person who is comfortable having difficult conversations and asking tough questions. While being brave in the name of the event’s success, a coach is respectful and supportive. Whether you are looking to hire or contract, the following are most have characteristics. The facilitator must be courageous. In other words, a person who is comfortable having difficult conversations and asking tough questions. While being brave, a coach is respectful and supportive. Communication is another soft skill that is critical for success. The ability to convey information in a clear, simple, and concise way. A person who practices active listening and can do so with people of different levels in the organization or levels of education. If they cannot explain something in simple words, it will not translate knowledge effectively. Explain something complicated without too many technical words is an elusive skill for many. Emotional intelligence skills are another characteristic of a kaizen facilitator Emotional intelligence is the ability to understand and manage your own emotions and those around you. People with a high degree of emotional intelligence recognize and understand their feelings and how they can affect other people. The emotionally intelligent person is skilled in four areas: identifying emotions, using emotions, understanding emotions, and regulating emotions. A facilitator must motivate, make others feel comfortable, overcome challenges, and manage conflict. Therefore, the ability to understand and manage their emotions to influence others in positive ways is critical. Social skills such as interpersonal relationships with empathy, compassion, and humility are essential for this job. With them, the facilitator will be coaching others to learn and be their best self. For instance, understanding human psychology and change management are key to influence people and drive a successful event. An honest and trustworthy individual who gives people credit for their ideas will navigate through the challenges of the event with greater chances of success. A facilitator must have technical skills A continuous improvement facilitator without technical skills and lean knowledge is not a good bet. Knowledge about continuous improvement and proven practical experience is non-negotiable. Moreover, problem-solving, time management, organization skills, and team building are also crucial. An energetic and passionate about continuous improvement person is the ideal driver for the cultural transformation from traditional to continuous improvement, one kaizen at a time.
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The Golden Thread: An Exhibition Celebrating 50 years (1966 – 2016) of the Arts in Richmond upon Thames Where will you find costumes worn by Rudolf Nureyev and Margot Fonteyn; Midsummer’s Night Dream enacted by puppets; and over 100 ceramic swans? The answer is at Arts Richmond’s 50th Anniversary. The Golden Thread exhibition includes exhibits from a wide range of arts and cultural organisations affiliated to Arts Richmond in an exuberant celebration of the wealth of the arts of all kinds in the borough. The Exhibition also highlights Arts Richmond’s own proud history of its contribution to Richmond’s rich and varied cultural life particularly through the Swan Drama Awards, Arts & Photography Exhibitions and Choral Workshops, and Literature events. To celebrate the Exhibition, Arts Richmond has programmed a series of showcase weekends, which will showcase a selection of societies current programmes, activities and events on the below dates: - Saturday 19th - Sunday 20th March: Visual Arts - Saturday 2nd - Sunday 3rd April: Drama and Dance - Saturday 9th - Sunday 10th April: Heritage - Saturday 16th - Sunday 17th April: Music - Saturday 23rd - Sunday 24th April: Literature/Shakespeare 400 Please download the brochure for more information [pdf]
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It’s not that I particularly like sepia – in fact, give me good ol’ black and white anytime. Or colour. But I belong to a small group of very sympa photographers and friends who get together in Menton and the surrounding villages to recreate the past in images of life as it was once lived. At the moment, we are ‘in the 1920s’ when sepia was still in use. In film photography, it was a chemical process carried out on silver-based photographic prints and had the advantage of being more resistant to the degradation of time. However, during the first decades of the 20th century this type of printing was being used less and less and by the 1930s had ended. There are ways of re-creating the sepia look in digital photography from a fairly straightfoward change of colour and tone to the using of a pre-set that makes the image look like a damaged and faded postcard. Here is a 1920s wedding that took place in the village of Gorbio last Sunday! The family pose under Gorbio’s 300 plus year old elm tree.
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This book is devoted to the first three provincial governors of Andros, Georgios Kliris, Konstantinos Rados and Ivos Rigas. These three young men were committed to the nation’s liberation and independence, they adhered to the Greek Revolution’s ideals, they served its institutions and they were inspired by them. Filiki Eteria was their common starting point; although their participation in the secret society left a deep imprint on their lives and contributed to the formation of long-lasting bonds, it had to remain in obscurity even after the consolidation of the Revolution. They became provincial governors of Andros, an island the course of which during the Revolution of 1821 had been similar, but in many ways distinct from that of the other Aegean islands. This book examines, among other topics, the intense political processes and social conflicts, the relationship between the island’s notables and the revolutionary government, the issue of tax collection and administration as well as the islanders’ everyday life during the Revolution. The last part of the book includes 80 documents related to the three men’s time as provincial governors of Andros, published here for the first time.
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Autoimmunity has become a huge issue in POTS (postural orthostatic tachycardia syndrome) and is becoming a major one in chronic fatigue syndrome (ME/CFS). The autoimmunity revolution underway in POTS – few now believe the disease doesn’t have a major autoimmune component – has come fast and fierce. Although it was less than five years ago that autoimmunity began to be a serious topic in POTS, researchers are now suggesting that the autoimmune findings in POTS may be the tip of the iceberg. They believe their results may play a role in other autonomic disorders including ME/CFS. The fact that this is happening in POTS – a condition which has received little funding from the NIH – is encouraging. It shows that even diseases without much funding can still at times make rapid strides if researchers explore the right areas. The Autoimmunity Revolution in POTS (Postural Orthostatic Tachycardia Syndrome) Dr. Kem has been behind a growing revolution in how to think about POTS. He believes that EBV, Lyme disease and other infections have activated enzymes that clip off loops found on the alpha/beta adrenergic receptors. He believes the damage to those receptors has so tweaked the immune system that it’s begun attacking them – triggering an autoimmune response. This work goes back almost twenty years to a finding that α1AR autoantibodies can attack a second extracellular loop (ECL2) in the adrenergic receptors found on our blood vessels. Jump forward to to 2011 when Kem and other researchers at the University of Oklahoma found autoantibodies to adrenergic and muscarinic receptors in a small cohort of patients (n=6) whose blood pressure falls dramatically upon standing (orthostatic hypotension). Most of these patients were medical mysteries – until this study; a larger, but still small study (n=20) in 2012 duplicated their findings and suggested that autoimmunity might be playing a role in other diseases characterized by problems with standing. Then, in 2014, the Oklahoma team also found β1AR‐activating autoantibodies in all of the POTS patients it studied and β2AR-activating autoantibodies in some. At this point, the Oklahoma team suggested that POTS may very well be an autoimmune disease and laid out a model of POTS pathophysiology. “These data support the addition of POTS to a growing number of cardiovascular entities with an autoimmune pathophysiology.” Li et. al. This damaged adrenergic receptor made it more difficult for norepinephrine (NE) to trigger a vasoconstrictor response to standing, leaving POTS patients needing 55% more NE than normal to tighten down their blood vessels. The “catecholamine surge” that resulted was a compensatory mechanism used to override the adrenergic receptor malfunction. The increased levels of stress hormones needed to compensate would likely leave POTS patients “wired and tired”. The problems POTS patients had maintaining their blood pressure caused their baroreceptors to become twitchy and hypersensitive. The end result of all this was the tachycardia (rapid heart beat) seen in POTS. It was clear that neither blood pressure nor heart rate regulation were working properly in POTS and the researchers’ autoantibody findings could explain why. They stated that: “These contrasting effects provide an appealing explanation for the cardiovascular effects associated with upright posture in those so afflicted.” Nor did they believe their findings were only going to apply to POTS. They believed a range of autoantibodies were likely producing a spectrum of cardiovascular dysautonomias. The kind of dysautonomia you had depended on the types and levels of autoantibodies present. The autoantibodies typically didn’t turn off a receptor response; instead, in an allosteric fashion, they inhibited its functioning to various degrees. They proposed that a novel therapeutic using IVIG or “decoy peptides” could be the answer for many with POTS and related diseases. The autoantibody work in POTS was just beginning, however. In a 2017 paper, the authors stated they believed the autoantibodies they’d identified were only in part responsible “for many of the cardiovascular manifestations” they’d seen in POTS patients. They believed that other autoantibodies were also playing a role, and in a 2018 paper in the Journal of the American Heart Association, they showed that as well. Another Damaged System Angiotensin II Type 1 Receptor Autoantibodies in Postural Tachycardia Syndrome Xichun Yu, MD, 1 , † Hongliang Li, MD, PhD, 1 Taylor A. Murphy, BS, 1 Zachary Nuss, BS, 1 Jonathan Liles, BS, 1Campbell Liles, BS, 1 Christopher E. Aston, PhD, 2 Satish R. Raj, MD, 3 , 4 Artur Fedorowski, MD, PhD, 5 , 6 , † andDavid C. Kem, MD. J Am Heart Assoc. 2018 Apr 17; 7(8): e008351. Published online 2018 Apr 4. doi: 10.1161/JAHA.117.008351 It turned out that another system that helps us stand is damaged in POTS as well. The renin-angiotensin-aldosterone system helps regulate our blood pressure when we stand, and its receptor – the angiotensin II (Ang II) type I receptor (AT1R) belongs to the same family as the adrenergic receptors the Oklahoma team had found problems with. That suggested to them that these autoantibodies might also be present in POTS patients. They were right. While none of the controls or the disease control group (vasovagal syncope) had autoantibodies to the angiotensin receptor, most of the 23 POTS patients in the study did. Further study revealed that the autoantibodies were indeed interfering with the system’s functioning. The renin-angiotensin-aldosterone system kicks in during more prolonged standing, but an animal model indicated that the effects were mostly the same as the earlier results in POTS – an inability to properly squeeze the blood vessels and stop the blood from pooling in the lower body. The end result was lower blood pressure levels in POTS patients with the ATIR antibodies than in POTS patients without them. The authors believed that the new autoantibodies may explain a mysterious group of POTS patients who have elevated angiotensin II levels but low aldosterone levels. They also suggested that the salt loading POTS patients typically do may be an attempt to compensate for this receptor’s blockage. In his conference talk, Kem reported that the M2 receptor in POTS patients is resistant to acetylcholine, the neurotransmitter driving the vagus nerve and the parasympathetic nervous system. Studies indicate that the M2 receptor blockage found results in a vagal withdrawal (reduced vagus nerve activity). Because the vagus nerve regulates the sympathetic nervous system, which helps control the heart rate, vagal withdrawal is yet another way to produce the heart rate increases seen in POTS. (Vagal withdrawal in POTS, ME/CFS and FM is reflected in low heart rate variability results). By 2018, then, the University of Oklahoma group had demonstrated, in mostly small studies, the presence of four different autoantibodies (α1AR, β1/2AR) that affect cardiovascular functioning in POTS. Earlier, the same research group found autoantibodies to muscarinic receptors in another disease of orthostatic intolerance called idiopathic postural hypotension. In a small 2016 study, Dubey’s findings suggested the same was true for POTS – bringing the number of possible cardiovascular system-affecting autoantibodies in POTS to six. “We Have A Potential For a Therapy” The big news from Kem’s talk was the real potential for a therapy – and not just a therapy which moves the needle a bit, but one which gets at the core of the disease. Here again, POTS researchers proved to be moving faster than ME/CFS or FM researchers. Neither ME/CFS nor fibromyalgia has an animal model, but at the conference, Kem reported that an animal model of POTS has been created. Kem has a novel treatment – a decoy peptide which causes the autoantibodies to bind to it instead of the damaged receptors. Using a mouse-sized tilt table, Kem tested the decoy peptide in the animal model and it worked – the mice experienced no heart rate increases when taking a tilt table test. Kem proclaimed, “We now have a potential for a therapy”, but he has hit a legal roadblock. It turns out that just two sentences in another patent described a similar method of using a “peptide decoy”. Despite the fact that the other patent didn’t test the idea or fully explicate it in the patent, the patent office is, thus far, denying Kem’s patent application – which he will need to raise money for the study. An appeal is underway and should be complete within 6-8 months. If successful, it will take a year to test the decoy peptide in laboratory animals. If that’s successful, a Phase II safety and efficacy study in humans would probably take two years. If that works out, then come the big Phase III studies; we’re looking at a minimum of five years, if everything goes smoothly, before a drug could come to market. If it does make it, though, it could be a very effective treatment for POTS. Kem is putting his focus on getting treatments to POTS patients first, and the antibody tests he’s using are not available commercially yet. Kem, though, appears absolutely sure that POTS is, at least in large part, an autoimmune disease. He believes all postulates needed by Witebskey’s Postulates for the presence of an autoimmune disorder have been fulfilled. From the discovery of perhaps six autoantibodies that are whacking away at the cardiovascular systems of POTS patients, to a potential treatment that appears, at least thus far, to work in an animal model, the POTS field, small as it is (the NIH didn’t even track POTS spending until recently), has been moving fast. Next up, a Mayo MD talked about an autoimmune disease he believes is greatly underdiagnosed in POTS, how he treats the autoimmunity he finds in POTS, the role he believes MCAS plays, and more. Autoimmunity, Sjogren’s Syndrome, Mast Cell Activation Syndrome and POTS – Brent Goodman MD Brent Goodman is a Mayo Clinic doctor hailing from Phoenix, Az who gets it. He came to talk about the complex situation regarding autoimmunity, MCAS, POTS and treatment. Some clues indicating that you may have an autoimmune condition include: acute onset, infectious onset, immunization onset, family history of autoimmunity, significant and rapid weight loss, onset during pregnancy – many of which we see in POTS, ME/CFS and/or FM. It’s a complex field. Unfortunately, most autoantibody tests lack specificity. (Ron Davis’s lab is working on better antibody tests). Plus, as Grubb noted in his earlier presentation, more than one autoantibody is usually present in an autoimmune disease. (Eight to ten are apparently present in rheumatoid arthritis. Thus far, about six have been associated with POTS, and more may be present in ME/CFS). The presence or absence of autoantibodies may not, however, correlate with disease activity, and autoantibody treatment may not result in reduced symptoms. Major fluctuations in symptoms in diseases like Sjogren’s Syndrome can obscure treatment effects. You get the feeling that while medical science has made strides with treating some autoimmune diseases, it’s still struggling to get a handle on them. Sjogren’s Syndrome – The All Purpose Disorder Goodman highlighted Sjogren’s Syndrome (SS). When you look for SS in POTS, he said, you will find it. He believes it’s an important part of POTS. Sjogren Syndrome (SS) is a subject that’s near and dear to my heart – my mother didn’t have ME/CFS, but she eventually died of complications from Sjogren’s in her fifties. SS is known for the dry eyes and mouth it often – but not always – produces, but it also has a predilection for affecting the autonomic nervous system. In fact, Goodman is so taken with the autonomic nervous system symptoms SS produces that he and his co-authors wrote in a recent study that: “A diagnosis of Sjögren Syndrome should be aggressively pursued in patients with signs and symptoms suggestive of autonomic nervous system impairment.” That small study suggested that autonomic problems run rampant in Sjogren’s Syndrome. All the participants reported lightheadedness, fainting or near fainting upon standing. Over half of his patients displayed exaggerated heart rates or increased blood pressure upon standing. Plus, the gastrointestinal and/or urinary symptoms so often present in POTS and ME/CFS were found in almost all the participants, and gut motility was impaired in 5/6 patients who underwent testing. Goodman is not the only one to notice the Sjogren’s autonomic nervous system connection. A larger Korean study found that autonomic problems were common in Sjogren’s and were associated with increased fatigue. An even larger 2012 UK study and a 2008 Swedish study suggested the same. Sjogren’s Syndrome – which was mentioned again and again at the conference – could be causing your POTS or ME/CFS-like symptoms. In fact, Goodman, who called Sjogren’s an all-purpose disorder, said that if you can think of a neurological condition, Sjogren’s can cause it. The good news is that if you do happen to have Sjogren’s Syndrome – instead of or in addition to POTS or ME/CFS – treatment possibilities are available: Goodman reported that three Sjogren’s Syndrome patients in his study who received immune therapy (IVIG or IVIG+Rituximab) improved significantly. After treatment, two of them no longer experienced any autonomic nervous system symptoms such as problems standing. Getting diagnosed with SS requires either positive antibody blood tests OR a positive minor salivary gland biopsy. Doctors who rely on antibody tests in combination with dry eyes/mouth to diagnose SS are behind. About 40% of Sjogren’s patients don’t have the SS-A or SS-B antibodies, Some never experience dry eyes or mouth. Dysautonomia International notes that younger SS patients with neurological symptoms may be more likely to have negative antibody tests. SS can affect the autonomic nervous system without producing either. - Check out the American-European SS criteria here. Mast Cell Activation Syndrome (MCAS) Goodman was another presenter at the conference who was very high on mast cell activation syndrome (MCAS). He believes MCAS is a common downstream consequence of Sjogren’s Syndrome. He gave another twist to the autoantibody findings in POTS when he reported that the adrenergic antibodies found in POTS can also activate mast cells. Lauren Stiles (Dysautonomia International founder), whose tortured path to her SS diagnosis can be found below, noted that her mast cells were going bananas until she got IVIG and then they quieted down. Goodman recommends MCAS treatment whether testing is positive or not if the symptoms fit the bill. (He treats the patients – not the lab results). Goodman noted that GI dsymotility (movement issues – either slowed or increased) are greatly underappreciated and can be severe in POTS. They can affect the gut (digestive problems) and/or the esophagus (swallowing problems) and require feeding tubes, resulting in hospitalization. He’s also finding that Cromolyn works great for gastrointestinal symptoms. Autoimmune diseases can produce so many symptoms that diagnosis can take a while. Goodman remembered a 36 year old woman diagnosed by a Mayo doctor with “adjustment disorder”, whom he, another Mayo doctor, later found to have POTS. She had indications of autoimmunity and he treated her with IVIG and methylprednisone and she quickly recovered. He wondered if early treatment (which rarely happens) could make a big difference. In people with Sjogren’s Syndrome and POTS, he reported that IVIG has an 83% success rate (!). Treatment can be tricky, though. Goodman described a Sjogren’s Syndrome patient who responded to IVIG, recovered, played sports again, and then developed a bad case of dry eyes/mouth and started producing antibodies to Sjogren’s. Goodman usually uses subQ immunoglobulin (SCIG, 0.4 grams/kg weekly) instead of IVIG in chronic conditions because of the risk of developing aseptic meningitis and because of headache problems. Goodman also uses methylprednisolone (1 g IV x 1-2 d.) instead of prednisone. The potential for the chronic side effects associated with prednisone use are minimal with methylprednisone. He also uses Rituximab a fair bit. - 2018 Dysautonomia International Conference I: Small Fiber Neuropathy, POTS, MCAS and Vagus Nerve Stimulation - The 2018 Dysautonomia Conference Pt. II: Could You Have a Spinal Fluid Leak? An ME/CFS, POTS, FM Perspective Thanks to Dysautonomia International for their support attending the conference. Next Up – An Entirely Different Kind of POTS – Hyperadrenergic POTS
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Making the decision between a lumpectomy and a mastectomy can be difficult. It’s a decision that is often left up to the patient, rather than the doctor. Understanding the advantages and disadvantages of each choice can help you make a more informed decision about the treatment option you choose. A lumpectomy, also called “breast conserving surgery,” is the removal of the cancerous lump in the breast, as well as a margin of tissue surrounding the cancer. A lumpectomy usually also requires radiation therapy, even if the cancer is limited to the breast tissue. A mastectomy, on the other hand, is the removal of one or both breasts, sometimes including the lymph nodes under the corresponding armpit. These two procedures have an almost identical success rate in terms of survival, but a lumpectomy has a slightly higher chance of the breast cancer recurring. Advantages of a Lumpectomy The main advantage of a lumpectomy is that the breast is conserved as much as possible. It is also a more minor surgery than a mastectomy, with a shorter and easier recovery time and fewer potential side effects. You can usually go home later in the day after a lumpectomy, rather than staying overnight in the hospital, as with a mastectomy. Disadvantages of a Lumpectomy Although the idea of keeping your beasts virtually intact can make the prospect of a lumpectomy more inviting than that of a mastectomy, a lumpectomy does have several potential disadvantages. First of all, a lumpectomy is usually followed by five to seven weeks of radiation therapy, to ensure that the cancer has been completely removed. The radiation therapy can affect the timing of any reconstruction, as well as your reconstruction options, depending on the extent of the radiation therapy needed. In addition, a lumpectomy does have a higher chance of a local recurrence of breast cancer than a mastectomy. If the same breast experiences a recurrence of breast cancer, additional radiation therapy is no longer an option, which means that you would have to undergo a mastectomy anyway. Factors to Consider In order to decide which procedure is best for your specific case, it is important to ask yourself some important questions. For example, how important is it to you to keep your original breast? Breast reconstruction is an option for those who opt for a mastectomy, but the breasts will not experience sensation and may require multiple additional surgeries in order to ensure that they are aesthetically pleasing. Also, you’ll have to consider the size of the cancer that would be removed by a lumpectomy. If the lump is very large, a lumpectomy may leave you with a distorted breast that can be very difficult to repair to your approval. In addition, your level of anxiety about recurring breast cancer should be taken into account, since a mastectomy radically lowers your risk of recurring cancer. Keywords: mastectomy, breast cancer, lumpectomy, radiation therapy
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Manchin deal could raise new hurdles for electric vehicle incentives Democrats’ push to boost electric vehicles could be hobbled by some of the protectionist supply chain provisions they included as requirements to get electric vehicle tax credits. The credits were included as part of the climate deal reached between Sen. Joe Manchin (D-W.Va.) and Senate Majority Leader Charles Schumer (D-N.Y.), even after Manchin had expressed some skepticism about them. In order for consumers to receive the full $7,500 for the purchase of a new electric vehicle, a portion of the minerals in that vehicle’s batteries will need to be extracted or refined from countries with free trade agreements with the United States. Part of the credit is also tied to a percentage of battery components being manufactured in North America. Experts and industry players have indicated that these provisions — particularly the critical minerals piece — represents a high bar, and may hamper electric vehicle adoption in the short term. John Bozzella, president and CEO of the Alliance for Automotive Innovation, said companies are working to bring more of their supply chain to the U.S. but that “it’s also a change that doesn’t happen overnight.” “A likely result of this bill (as currently constructed) is that a significant number of consumers will not be able to take advantage of this credit in the early years when it is needed the most,” Bozzella said in a statement. Electric vehicles have been a central component of Democratic plans to combat climate change, and EV tax credits were included in various iterations of President Biden’s Build Back Better package. The Manchin-Schumer bill gives tax credits worth up to $7,500 to consumers to incentivize the purchase of new EVs, but half of those credits — amounting to $3,750 — is dependent on where the minerals in its batteries come from. The legislation mandates that 40 percent of the value of the minerals used in the electric vehicles’ batteries are extracted or processed from countries where the U.S. has a free trade agreement, and ratchets up over time. For 2024, it increases to 50 percent, and continues upward until 2027, when 80 percent of the minerals used must come from these countries. An auto industry source told The Hill they believe there are currently no electric vehicles on the market that meet this requirement. “I think it’s going to take several years to get there,” said Duncan Wood, vice president for strategy and new initiatives at the Wilson Center. Wood added that the fact that the requirements ratchet up over time “presents a challenge” but said that with enough effort, they may be achievable. “If you have the time, if you have the right incentives for the mining sector and if you have the processing and refining plants being built, then it’s entirely possible that you could meet some of those targets,” he said. “It’s going to take a Herculean effort to get there,” he added. “The good thing about this legislation is that it does provide those deadlines and those deadlines will be an incentive for people to move forward.” The U.S. has free trade agreements with some major mineral producers like Australia and Chile, but doesn’t have any such agreement with other major producers like China, Russia and the Democratic Republic of the Congo. “The numbers that they quote in there are very high and very soon,” said Morgan Bazilian, a public policy professor at the Colorado School of Mines. “Will those targets become a hindrance or an obstacle to the adoption of electric vehicles with those targets? Yes, if they are adhered to precisely and exactly,” he said. The bulk of the world’s mineral refining is done in China. “If you look across the battery materials from lithium, cobalt, manganese, nickel, graphite, you will see that almost all of them are completely processed … in China,” Bazilian said. “That ranges from 75 to 100 percent for all of the things I just mentioned.” E&E News previously reported that some of the supply chains required by the credit don’t exist. The other half of the credit is tied to battery components being manufactured in North America. Ethan Elkind, director of the climate program at the University of California, Berkeley’s Center for Law, Energy and the Environment, said that while he believes most battery manufacturing is happening offshore, companies may be able to bring it to the U.S. relatively rapidly. “They can get these facilities up and running sometimes pretty quickly, but it depends on the state because permitting challenges can definitely hold back some of this manufacturing,” he said. The industry source noted that the stipulations may not just limit new adoption, they may also pause existing tax incentives for consumers who purchase an electric vehicle. Current credits are capped at 200,000 vehicles per automaker and phase down from up to $7,500 per vehicle after that. Some automakers either haven’t met the cap or are currently in the phase-down period, but their customers stand to lose that credit moving forward if their vehicles don’t meet the new requirements. The source said there is a push for changes to the bill, including moving back the timeline for some of the stipulations. Bloomberg reported that Ford, General Motors, Toyota and Stellantis are involved in those efforts. In a statement on Monday, GM described some of the provisions as “challenging” and said that they “cannot be achieved overnight.” Caps on both consumer income and vehicle value — which limit the credits to vans, SUVs and pickups $80,000 or less, and other vehicles costing $55,000 or less — are also posing hurdles for some automakers. Jim Chen, Rivian’s vice president of public policy, said that based on his company’s current trajectory, the credit wouldn’t be able to work for the company’s consumers until 2025, because its vehicles are too expensive. “The new proposal pretty much cuts us off at the knees. … It basically renders our vehicles ineligible,” said Chen, noting that his company was also pushing for changes.
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As the pace of COVID vaccination increases, the pace of economic activity around the world should increase as well. This will present opportunities, but also challenges. How can we renew faith in and reliance on democracy and free markets as the planet transitions to a post-COVID world? To begin seeking answers, the Center for International Private Enterprise (CIPE) and the Free Enterprise & Democracy Network (FEDN) recently hosted a conference titled “Towards Successful Transitions: Economic Recovery and Democratic Renewal.” Carl Gershman, outgoing president of the National Endowment for Democracy, set the tone in an opening keynote. “Political democracy, with a strong free market system, is the best path forward for people everywhere,” he reminded listeners. “A free market is not a feature; it is a requirement for good governance.” The problem, as he sees it, is that the people who have tried to defend democracy too often fail to link it to the free market. That is where CIPE helps. CIPE works with local business leaders to expand the opportunity for inclusive growth through market-led solutions. CIPE programs promote a rule-based system that emphasizes principles of democratic governance, enables entrepreneurship, opens trade, and fights corruption. CIPE and its global partner network create knowledge and practical tools to drive local change. For example, CIPE developed Business Associations for the 21st Century, a business association management guidebook that helps associations develop effective governance, programs, and advocacy efforts in order create more favorable business climate in their countries. CIPE also published Cost-Benefit: A Practical Guide for Civil Society Organizations. Coming out of the COVID pandemic, local action will be more important than ever. A global contagion was felt at the individual level, shuttering businesses of all sizes. Local chambers of commerce and business associations have the on-the-spot expertise to help owners reopen and recover, and the political influence to obtain the help these businesses will need. They can also work through the Free Enterprise and Democracy Network. FEDN provides a mechanism for private sector leaders and advocates of freedom across the world to exchange ideas, support one another, and make the case for democratic, prosperous societies. FEDN currently has more than 60 distinguished members from 38 countries, articulating priorities for crisis response and recovery while showing solidarity with businesses and civilians facing repression. The conference also considered the large role governments will play in the recovery. During her address, Hon. Betty C. Maina, Kenya’s Cabinet Secretary for the Ministry of Industrialisation, Trade and Enterprise Development, detailed how close collaboration with the private sector has allowed her country to implement an inclusive growth agenda, social protects and welfare to support the population. She said that win-win outcomes are possible between states and private enterprises globally, but only when they work together to support one another to advance prosperity for all rather than viewing each other as antagonists. During panels, breakout sessions, and in polls, conference participants discussed the need for governments to help small business, the needy and the poor to weather the lingering effects of the pandemic. At the same time, governments at all levels must be prepared for the rapid changes and disruption in business models that are certain to come. They should also be ready to take advantage of the move toward democracy if it presents itself. “Democratic transition often does not come incrementally. It comes in waves,” warned Abigail Bellows, a Nonresident Scholar at the Carnegie Endowment for International Peace. She told attendees that “it is very important to be prepared for those moments and be able to respond strategically.” The means moving rapidly to capitalize on opportunities for transformational reform. Some potential opportunities include a realignment towards democratic capitalism, remaining conscientious of blind spots in policy efforts aimed at balancing outcomes, rebuilding citizen trust through transparency and accountability, as well as recognizing stakeholder dialogue and engagement as a continuous and reciprocal process. In the closing remarks for the conference, FEDN Steering Committee Member Badri el Meouchi summarized key takeaways of the conference. Countries must: - Invest more in collective action among the public sector, private sector, and civil society. - Expect change and always be ready to respond to waves of change. - Empower local actors to push for reforms and be more involved in policy decisions. - Strengthen anti-corruption efforts to curb the erosion of free enterprise and democracy. The pandemic showed us some of the best examples of private-public collaboration. Business and government can be equal partners, and this is often extremely effective. Together, they highlight FEDN’s themes of free markets and democracy. As the world looks to recover, it needs more of both of these.
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If you haven’t started your three year old on Mozart yet, you just might be in for some big problems in New York. That’s because she’s already behind the curve, as parents are going crazy trying to make sure that their little ones get into the right nursery school and kindergarten programs. Getting a Gifted Spot New York City has a number of gifted kindergarten programs, and they are so coveted that 14,000 preschoolers took the test this year for only 2,700 spots. Parents want their little ones to have a leg up so badly that they are using test-prep books and services like TestingMom.com in order to put in long hours of test preparation before the big day. While experts do agree that coaching bright kids can raise their test scores a great deal, these same experts aren’t weighing in on the emotional and psychological damage that this race might create for sweet young people. Chavon Peele, a mother in the area, said, “Even though I think it’s unfair that some people don’t have the resources to prepare, I’m going to be one of those who prepare. I do it because she has to stay competitive.” Michael McCurdy and Karen Quinn have launched TestingMom.com together. Membership starts at $14.99 a month and includes some 5000 practice questions to help kids get into gifted programs, private schools and beyond. Make ‘Em Sit Young Brooklyn mom Elana Walsh explains that it’s imperative to “train your child to listen to instructions and be able to sit.” Never mind playtime and childhood fun. Sometimes, even those who achieve the desired goals end up disappointed. The Brooklyn School of Inquiry, for instance, which is a citywide gifted school, has so many kids who apply and score well on the test that they hold a lottery. And sometimes, even the most gifted of kids aren’t holding the winning ticket.
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Pi Network and its native Pi currency are a hot and interesting recent development in the areas of crypto-currency and social platforms. It’s interesting both for its scope as well as approach. The current homepage of the project is at minepi.com/ but information is very limited, which is the reason for this post. The crypto currency known as just “Pi” is innovative because it supposedly combines a variant of the Stellar Consensus Protocol SCP with a trust network composed of real humans and their real-world trust relationships. The scope of the project also includes a social platform and marketplace where to spend Pi even before it gets listed on an exchange for goods and services of and by members of the Pi Network. Pi has nothing to do with the now defunct PiCoin, and there is no exchange trading Pi yet. The approach the “semi-stealth” start-up is taking to develop their product is innovative in how it opens its doors to the public very early on to solicit input without having all answers ready yet, and how it tries to build a product based on input and contributions from outside. It is a leap of trust for the early participants, but it could be rewarded by the Pi they accumulate in the process before the final product is launched. The reason for jumping on this bandwagon now, as a beta program participant, is that the project is very early stage, and you can still earn Pi coins at a higher rate in return for your help developing the product. As more people join over time, the amount of Pi paid out will reduce, similar to the block reward halvings of other crypto-currencies. We explain how to get access and sign up later below. Beta program participants need to exercise a lot of patience. We will update this post with information not included in official resources, and some of it may be speculative. For the official sources of information scroll down to the references section. What Pi will be for The currency Pi will be the medium of exchange on a new platform that might evolve from the current basic discussion forum app to a peer-to-peer marketplaces where users will be able to exchange goods, services, and even user’s attention (to advertisements.) One of the key ideas appears to be that the users, who earn Pi coins simply by participating in building out the network of trust, will own a fair part of the platform. The platform will replace (expensive) middlemen such as Facebook, Ebay, Apple and Google, and return control over and ownership of your social interactions back to you. The value of the platform will drive the value of Pi. Platform users will hold Pi themselves and thereby own the platform. And users interacting among each other will be the value of the platform. Who are behind it The app on Apple App Store is distributed by SocialChain Inc., a Delaware company. Do not confuse SocialChain Inc. with corporations with similar names that are incorporated elsewhere. The Stanford graduates developing this project are from the Stanford Blockchain Collective. The IDs used by that core team combined with some Internet searching will quickly lead to identities of a number of people. The “core team” consists of three people, with apparently a center of gravity in building social systems: Vincent McPhillip @vince – Head of Community Mr. McPhillip studied political science at Yale (BA) and business at Stanford (MBA), and seems interest in building social movements, and in particular into democratization of wealth distribution. Nicolas Kokkalis @nicolas – Head of Technology Dr. Kokkalis was affiliated with Stanford and has published a number of papers related to motivating people to contribute to a common goal. Co-authors include Dr. Fan (see below), and Prof. Michael Bernstein (Standford faculty) who is studying crowdsourcing. Dr. Kokkalis is a computer scientist. Dr. Chengdiao Fan @cfan – Head of Product Dr. Fan was a collaborator on some of Nicolas’ papers, while affiliated with Palo Alto University. According to her profile and LinkedIn she graduated, studying Computational Anthropology, from Stanford. The corporate structure supporting their entrepreneurial activity seems to be SocialChain Inc., however, there are three other companies with a similar name: Social Chain USA, Inc., and a third, SocialChain Holdings LLC with a different registered agent. SocialChain, Inc filed incorporation on September 14, 2018 in California, with Dr. Fan as President, and sole officer. The foreign entity is SocialChain, Inc, incorporated in Delaware, of which Vincent PcPhillip seems to be President. What it (could) costs It is possible today to join the project and earn Pi, by being part of the beta program. A common questions is what it would cost you. The answer is nothing really. The coin is not really mined using computing power, and all that’s needed is tapping a button in the Pi App to prove you (still) are a real human. Therefore there is no real cost involved. You can even turn off the app and the accumulation will continue for 24 hours. The App does not use CPU cycles, bandwidth or any other resources. There have been no reports of any malicious behavior either. A Google Captcha v3 algorithm is used to ensure you are a human. Beta participants contribute their real name and phone number. However, many services ask the same if not more. Other than that, tapping the app once a day is all that’s needed. There is of course a real risk that the core team will just build a database of millions of people who trust each other, and sell it to the highest bidder, and abandon all work rendering Pi worthless. Another risk is that in order to redeem Pi for the real thing users will be asked to provide far more personal information than just a phone number, potentially not making it worthwhile, or still risking the scenario above. What you (could) gain Besides earning Pi early-on at a higher rate than possible in the future as the network grows beyond 100k, 1M, 10M users and the rewards halve each time, people could guide the project with ideas and contributions. Right now you can grow the trust network by inviting people you know. You can observe how a start-up struggles and evolves into a large business that might eventually become a next Facebook or Ebay. And with the Pi you accumulate on the way, you could accumulate some ownership. Following the progress of a start-up from early beginnings itself can be a valuable experience, and there are many opportunities to make new friends, and supposedly there will be opportunities to contribute directly as well. However, there is no guarantee for any of this. What you are getting is a lottery ticket that could become worth a lot of money in the future if the project succeeds, or nothing at all and disappointment if it fails. The odds are by far better than that of a regular lottery ticket, but they are not that high either. How to start earning Pi To sign up for the beta to join the community building a trust network while earning Pi coins along the way, you can download the Pi Network app from Apple App Store, or Google Play Store. If you wish to obtain an invite code from a trustworthy source to join, leave a message below this post with a valid email address, and why I should trust you. Without explanation why I should trust you I won’t send you a code. If you request a code, your message won’t be posted below on this blog post but you will receive a code instead via the email you provide. (You can trust me because this site provides the research you need to know what you are getting into.) At signup in the App, you will need to provide your real name (this will be a requirement to claim your Pi once main net launches) and your telephone number. Your name will be known to only the person who invited you, and the core team. The phone number will be only known to the core team of Pi Network. It is possible to hide your name in your mining circle. After joining, all you have to do is press a button in the app to start a next 24h period of “mining.” After three of such periods, you can start adding people from your mining group to your trust circle, and earn Pi at a higher rate. Ultimately you will want to have about 5 people in your trust circle who you know and trust well. This will then work together with a Pi coin mining node running on a PC to secure the network while avoiding high cost of power of Proof-of-Work alternatives. You may earn Pi for running such a node, but the earning rate has not been determined yet. Unofficial Telegram and Discord While most discussion is supposed to stay in the Pi App, and while the development of the messaging within the app should introduce new features based on community input, there are unofficial channels that may be more familiar and easier to use, and that remain outside of the control of Pi Network. Ask for them on the chat in the Pi App. This invite link was posted recently for a Discord server The Pi Network: https://discord.gg/VQMYgay For official information known already read the white-paper draft and the FAQ: - Home page: https://minepi.com/ - Official FAQ: https://minepi.com/faq - Official Whitepaper: https://minepi.com/white-paper - Facebook: https://www.facebook.com/PiCoreTeam/ May 22, 2019: 10k e-Pioneers; halving to 0.78 Pi/hr July 5th 2019: 100k e-Pioneers; halving to 0.39 Pi/hr October 30th 2019: 1M e-pioneers: halving to 0.2 Pi/hr base rate e-Pioneer is unofficial for so called Engaged Pioneers, which excludes people who signed up but gave up on participating with the app within days. updated: 20190516; 20190714; 20191030 photo: ideanist M
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Environmental Sounds Influence the Multisensory Perception of Chocolate Gelati. Lin YHT., Hamid N., Shepherd D., Kantono K., Spence C. Recently, it has been shown that various auditory stimuli modulate flavour perception. The present study attempts to understand the effects of environmental sounds (park, food court, fast food restaurant, cafe, and bar sounds) on the perception of chocolate gelato (specifically, sweet, bitter, milky, creamy, cocoa, roasted, and vanilla notes) using the Temporal Check-All-That-Apply (TCATA) method. Additionally, affective ratings of the auditory stimuli were obtained using the Self-Assessment Manikin (SAM) in terms of their valence, arousal, and dominance. In total, 58 panellists rated the sounds and chocolate gelato in a sensory laboratory. The results revealed that bitterness, roasted, and cocoa notes were more evident when the bar, fast food, and food court sounds were played. Meanwhile, sweetness was cited more in the early mastication period when listening to park and café sounds. The park sound was significantly higher in valence, while the bar sound was significantly higher in arousal. Dominance was significantly higher for the fast food restaurant, food court, and bar sound conditions. Intriguingly, the valence evoked by the pleasant park sound was positively correlated with the sweetness of the gelato. Meanwhile, the arousal associated with bar sounds was positively correlated with bitterness, roasted, and cocoa attributes. Taken together, these results clearly demonstrate that people's perception of the flavour of gelato varied with the different real-world sounds used in this study.
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This article originally appeared on VICE Asia Last week, a Malaysian singer was arrested for keeping a wild animal in her home. That animal turned out to be a sun bear—but 27-year-old Zarith Sofia Yasin, a former contestant on reality singing show Rockanova, insisted that she thought it was a dog. "It was night time when I found the bear cub in a weakened state by the side of the road, and I thought it was dog!” Zarith told Malay daily publication Kosmo—later explaining to The Star that she’d found the animal nearly two weeks earlier and picked it up in the hope that she could rescue it and nurse it back to health. "I know the bear cannot be reared, it can't be kept as a pet,” she said. "I only wanted to save the bear, I had no intention of exploiting it.” On June 7, the Department of Wildlife and National Parks Peninsular Malaysia (Perhilitan for short) raided Zarith’s condo unit in Desa Pandan, Kuala Lumpur, following a tip-off from a local resident. Someone had reportedly spotted the bear sticking its head through the open window of the unit “crying out for help,” in an incident that was filmed and uploaded to Facebook: Zarith was arrested on suspicion of keeping an endangered animal in her condo, while online commentators accused her of trapping the bear in her home with the intention of selling it illegally. Two days after her arrest, the disgraced singer came forward to tell her side of the story and to clarify her intentions with Bruno. As Zarith tells it, her aim was always to hold on to the bear until it regained its strength and she could hand it over to the zoo. "I didn't put him in a cage because I didn't want him to stay there for too long—that would have been even more cruel,” she said, as a way of explaining why the animal was roaming loose around in her apartment, and denounced allegations that she had hoped to sell Bruno off. "I have a business to run during the day and at night, I sing… when do I have time to sell animals?” she said. "This is not the way I make a living. Animals like that are not for sale." Zarith further noted that she had taken good care of Bruno and fed him well, suggesting that "if Bruno could talk, it would surely say the food I gave him was delicious. It ate chocolates!" Bruno is estimated to be between five to seven months old, and was in good health when seized by authorities. He has since been sent to a wildlife rescue centre. The Star reported that authorities have not yet decided whether the bear should return to the wild, given its young age. Zarith, meanwhile, says she is ready to face the legal consequences of her actions. Sign up for our newsletter to get the best of VICE delivered to your inbox daily.
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Do you know what it means to be a digital citizen? Digital Citizenship includes: You can watch the following videos for a review of digital citizenship concepts (thanks to Nearpod and Flocabulary <-- Miss Gilpin cites her sources!) Play Newsfeed Defenders! Hello, Canyon Cowboys! My name is Miss Gilpin and I am SO excited to be your new teacher librarian! I can't wait to get to know you this year. See you around campus!
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Room: Exhibit Hall Purpose: While several ICRU reports recommend planning target volumes (PTVs) in radiation therapy, the frequency of PTV use in routine clinical practice for patients who have undergone breast-conserving surgery is not known. A statewide consortium, focused on quality improvement, evaluated whether or not a PTV was created for the lumpectomy cavity for these patients. Methods: Baseline data regarding lumpectomy cavity PTV delineation use was acquired from 22 institutions for patients who underwent breast-conserving surgery from 2011 through mid-2016. In 2017, a consortium-wide performance metric was established requiring PTVs for the lumpectomy cavity with the purpose of ensuring adequate target coverage when cardiac dose is considered. The PTV delineation rate was evaluated before and after introduction of the performance metric. Starting in August 2017, the expansion size was captured. Results: For patients who completed radiotherapy before the intervention (2011- mid-2016; N=6278), 35.0% had a PTV delineated. For patients who completed radiotherapy after the intervention was required (2017; N=1890), this percentage increased to 77.8%. During that time, PTV adoption rates varied by institution (N=22) with 9 institutions delineating a PTV for 90% or more of their patients, 8 between 50-90%, and 5 less than 50% at the end of 2017. The median PTV expansion used by institutions was 1 cm (range 0.1-2 cm). Conclusion: Introduction of a consortium-wide performance metric was an effective intervention, increasing the PTV delineation rate for the lumpectomy cavity for radiation therapy patients who have undergone breast-conserving surgery. This increase in PTV use will allow the consortium to make target dose homogeneity and coverage recommendations which may aid in weighing clinical tradeoffs between target and heart doses. Future work will investigate the relationship between lumpectomy cavity expansion size as a function of whether or not daily or weekly imaging is used amongst clinics within the consortium. Funding Support, Disclosures, and Conflict of Interest: Work funded in part by Blue Cross Blue Shield of Michigan and Blue Care Network.
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I am slowly going through Levi’s diary looking for mentions of the Indian depredations and his request to the government for reimbursement. Once I have gone through the entire diary, I will post all the mentions. There is no surviving diary of the early 1860s in which the events occurred. However, his son Levi M, who was 10-15 years old at the time has left an account in his remembrances and life history (originally transcribed and typed in the 1930s as part of the Federal Works Progress Administration and further edited by Lynn Hilton in 1955). The following are of note: When others left, Levi bought $1000 worth of land, which he eventually had to leave. Although it was resettled, he never received payment for the land. This may well be the bulk of the money Levi was asking for restitution. The remainder would be any additional land that he owned, improvements he made upon the land, and the stock that was lost. Levi M thought Toquerville a “miserable poor place” (although earlier he refers to it as a “pleasant winter resort”) His views towards Native Americans were decidedly white-centric (probably most other settlers had similar views), and reading between the lines of what is below and some additional paragraphs I did not post, we can see that he thinks his culture and religion is superior to that of the Native Americans. “In the fall of 1863 we moved our stock to Kanab in Kane County U.T. and the women folds remained here—-Toquerville—-during the winter. In the spring the women folks joined us on the ranch at Kanab, but returned to Toquerville to spend the winter. Thus we had a good farm and ranch for to produce our living upon, and although it was upon the frontiers, yet the numerous Indians of that region—the Pieedes—appeared to be perfectly harmless and friendly. And Toquerville afforded us a pleasant winter resort among refined company. In consequence of the scarcity of water, seven out of the first fourteen settlers at Kanab became discouraged and sold their claims and improvements to father in July 1864. He paid them something near 1000 dollars for their claims in stock. This together with the improvements that he had made for himself he lost entirely in the Indian difficulties that followed. And not standing Kanab had been resettled since he lost it yet he has never received any remuneration for his property that the new settlers are using. In the fall of 1865 the Indians became somewhat troublesome in the Kanab country. The true cause of this change in their actions I have never been able to discover. But those who resided there became somewhat troublesome in the Kanab country. The true cause of this change in their actions I have never been able to discover. But those who resided there became saucy and commenced killing cattle upon the range. Never before had we seen anything like this aggravating policy in them, and if they had before killed cattle it was upon a very small scale and not found out. Soon after our arrival at Kanab, while I and an old man by the name of Strong were the only white persons there, a party of Navajo Indians passed by and drove off a herd of horses among which were two of father’s. But we were not more molested nor our stock until the fall of 1865, as above stated. The Indians could not plead that we were penurious with them, for we employed them and paid them provisions and clothing, plowed their land for them, loaned them farming tools and showed them how to cultivate their land, and, during the summer of 1865, father gave to them one whole beef and one sheep for a feast. In the difficulties that followed, our home Indians, the Pieeds claimed to take no part, but said the depredations were committed by the Navajos from the South side of the Colorado River: and to be sure they—the Pieedes—were not actually caught in any of the troubles, still circumstantial evidences were strong against them so much so that some fifteen of them were killed during the winter of 65—6 by our people who found them with stolen property such as, skins of sheep and cattle, money, pocket knives & belonging to persons who had been killed by Indians, or had lost property by their depredations. They probably assisted the Navajos to say the least. The raids were made invariably in a dark of the moon. Generally the thieves would visit a ranch in the night, pillage the yards and stables and gather stock from the range. Thus they would secure several hours the start of their pursuers, and they drove the stolen animals so rapidly that they generally succeeded in their scandalous enterprises. But when overtaken they would simply leave the stock and scamper into their houses, but if they found one or two men traveling upon the range or the road they did not hesitate to take their lives. This made it extremely dangerous for anybody to be out alone. So we were obliged to be very careful. I have rode many days upon the range alone, but I supposed that I did not cross their path and so they did not molest me. They made their first strike at the Pairhiea, the outer settlement; next they made a raid at Kanab; next at Pipe Springs; Dr. Whitmore’s ranch and succeeded in murdering the Doctor and a hired man, Robert McIntyre, who were out upon the cattle range. The Indians always crossed the Colorado River with their plunder. Early in the fall at a general Conference at St. George, the conditions of these frontiers were discussed, and the Priesthood there sent some of the brethren to these outer settlements counsel was generally complied with by concentrating at Kanab and Long Valley. In the spring of ’66 by counsel all concentrated at Long Valley, and a few days after our arrival there the Indians following up, made another raid in which they took the last horse my father had. At this time they killed two men and one woman by the name of Berry. Our women folks had not spent this winter in Toquerville, because the counsel was for all to remain at Kanab, so they had their share of the excitement. Soon after we got our crops in at Long Valley, counsel came again for us to move into the interior totally. So having been harassed several months by Indians losing our land and improvements at both places, besides a great amount of stock we found ourselves at Toquerville in the month of July 1866, glad that our lives had been sparred. Father, being completely tired of frontier life, determined to settle in this miserable poor spot—Toquerville, and let somebody else go onto the borders. So he let what stock—-cattle he had to Wm. Maxwell who took them to Spring Valley, in Eastern Nevada. Father sold what sheep he had left, and we commenced to improve a small portion of land that he had bought there. He had resided here ever since and has a good little vineyard and orchard and a comfortable home, but I have not been here constantly as I shall here after record. During the summer time the Indians did not trouble much except to kill one man who was out upon an exploring expedition with Capt. James Andrus. Some thought the Indian war over.”
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The oldest Chinese-language newspaper in circulation is closing dozens of bureaus across China and laying off scores of staff. Chinese netizens rejoiced at the news, and analysts say the winding down of the Hong Kong-based paper is the consequence of a fierce factional struggle in the Chinese Communist Party. A total of 21 Ta Kung Pao offices in mainland China, including in Beijing, Shanghai, Shenzhen, and Fujian, will be shut, and the contracts of staff terminated, according to a notice from the company on Oct. 30 leaked on Chinese microblogging site Sina Weibo. The paper’s businesses on mainland China will cease by the end of the year, the notice continued. About a 100 staff will be fired, according to Apple Daily, a Hong Kong broadsheet, citing internal sources. A Ta Kung Pao staff later told Hong Kong media that the move was merely “normal business restructuring,” and declined to comment further. Previous reports in Hong Kong media had said that Ta Kung Pao might merge with Wen Wei Po, another Hong Kong publication. Ta Kung Pao was founded in the northeastern city of Tianjin in 1902, and the paper originally vowed never to align with political parties, governments, businesses, or individuals. Both Ta Kung Pao and Wen Wei Po, however, are presently controlled by the Liaison Office, the Chinese regime’s official presence in Hong Kong. “Even though Ta Kung Pao and Wen Wei Po are distributed free, nobody wants to read them. They are just regime mouthpieces, so it’s little wonder that the people of Hong Kong don’t respect them,” wrote a netizen from Shenzhen, a city in mainland China just north of the Hong Kong border. Another netizen questioned: “What’s this? No need for a fake Hong Kong publication to extol the Chinese regime?” Analysts say the Party is merging the two pro-Beijing newspapers to save resources. Hong Kong “businesses and companies in mainland China all know that Ta Kung Pao and Wen Wei Po have no readership in Hong Kong,” Cai Yongmei, executive editor of Hong Kong publication Open Magazine, told NTD Television. (NTD and Epoch Times are subsidiaries of the New York-based Epoch Media Group.) Placing an ad in those newspaper is “like throwing money into water—you won’t get any customers,” Cai also said. The bulk of advertisements in Ta Kung Pao and Wen Wei Po are either political in nature or from companies linked to the Communist Party. Both papers currently receive direct funding from the Party. In 2014, the Liaison Office gave each $12.9 million, according to a report in the Hong Kong Economic Journal. Other analysts say the closing of Ta Kung Pao is part of Party leader Xi Jinping’s attempt to root out a political faction led by his predecessor, former Party boss Jiang Zemin. Ta Kung Pao is believed to be allied with the Jiang faction because it promoted disgraced Chongqing chief Bo Xilai’s political campaigns when he was in power. In 2012, the paper hosted in Hong Kong a performance of “red songs”—tunes praising the Party and Chairman Mao Zedong that the Chinese people were made to sing during the tumultuous Cultural Revolution. Jiang Zaizhong, the former head of Ta Kung Pao, attended every performance, and claimed he had “fresh feelings and understandings after every performance.” Bo had started the “red song” campaign in Chongqing to advance his political ambitions. The following year, Ta Kung Pao wove a threatening political message into a fabricated story featuring Xi Jinping. Party mouthpiece Xinhua News Agency hastily demanded its retraction, but not before it was picked up by Chinese netizens and overseas Chinese publications. By forcing Ta Kung Pao and Wen Wei Po to merge, “Xi could then effectively control these media, and the opposing faction cannot use them to attack him,” Hua Bo, a Beijing-based political analyst, told NTD.
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I’ve been playing around with Azure Functions recently. One thing I like about them is how you can code, test and view the logs real-time from within the Azure Portal – below you can see me testing my Burger Tax function! One thing I was interested in doing is getting access to the logs remotely (directly from my machine rather than going through the Azure Portal). It turns out that you can do this using the Azure Functions Core Tools. I installed the Core Tools (the Azure CLI is a pre-requisite) and after logging into Azure using az login. I could connect to the logs using this command: func azure functionapp logstream <FunctionAppName> In the example below, I connected to an Azure Function App named burgertax26343 (A very catchy name I know!). To over-complicate things I ran this within Ubuntu running on WSL on my Windows 11 device – you can of course run this natively on Windows, macOS and Linux. I then fired up PowerShell to send a test request to the Azure Function App using Invoke-RestMethod (this example is a Starling Bank webhook, read more about how I’m using this here). After running this, I flipped back to the other terminal window, where I could see the output – in this case it used Write-Host to confirm that the function had triggered and outputs the name of the merchant (Next in this case).
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Computer Networks and Inventive Communication Technologies: Proceedings of Third ICCNCT 2020 by S. Smys English | EPUB | 2021 | 1212 Pages | ISBN : 9811596468 | 215.7 MB This book is a collection of peer-reviewed best selected research papers presented at 3rd International Conference on Computer Networks and Inventive Communication Technologies (ICCNCT 2020). The book covers new results in theory, methodology, and applications of computer networks and data communications. It includes original papers on computer networks, network protocols and wireless networks, data communication technologies, and network security. The proceedings of this conference is a valuable resource, dealing with both the important core and the specialized issues in the areas of next generation wireless network design, control, and management, as well as in the areas of protection, assurance, and trust in information security practice. It is a reference for researchers, instructors, students, scientists, engineers, managers, and industry practitioners for advance work in the area.
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by Gabe Bullard Kentucky state government is asking broadband users to take part in a statewide internet survey. Users can log on to a state website that will check their location and connection speed. The information will be used to develop a map of internet access and quality in the commonwealth. Finance Cabinet spokesperson Cindy Lanham says the call for users to participate in the survey went out Thursday and the response has been strong so far. “People get the idea that their input is needed to make decisions that could impact economic development, they could impact their local school district, and impact their homes and their businesses,” she says. The survey is funded with a $2.1 million stimulus grant. Lanham says once the map is created, it will be used to create a plan for improving access. That plan will be used to apply for more federal funds. To take the survey, click here for the home test and here for the business survey.
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The Ferment: Youth Unrest in India Author : Nikhila Henry 9789386215437 | PB | pp. 278 | 2018 | Macmillan Publisher The wave of youth protests, agitations, and marches that gripped India in the last few years were not, Nikhila Henry argues, sporadic, isolated, or piecemeal. Rather, they were an organized effort against a fractured, unforgiving, and deeply discriminatory society. Ships in 2-4 days Out of stock ‘From JNU to Jadavpur, anti-national movement spreads!’—Zee News ‘Activism or anti-nationalism?’—Times Now ‘Dalit students on warpath after Vemula suicide’ —First Post ‘Violence on Ramjas campus: no room for free, peaceful political debate’—NDTV ‘Kashmir University students protest anti–free speech circular’—Quint These are but a tiny sample of headlines that have become commonplace in India in recent years. What is it about the present moment in the life of our nation that has stirred so many thousands of young citizens into political action? And what is it about the nature of their protests that is threatening enough for the establishment to brand it ‘anti-national’? The wave of youth protests, agitations, and marches that gripped India in the last few years were not, Nikhila Henry argues, sporadic, isolated, or piecemeal. Rather, they were an organized effort against a fractured, unforgiving, and deeply discriminatory society. The participants, despite differences, often found convergence and empathy for each other, and fought larger battles: battles of the Dalit, of the Adivasi, of the Kashmiri, of the Women, of the Muslim. In so doing, it was not simply entrenched discrimination they highlighted. In so doing, they questioned fundamental ideas of public morality and the very essence that makes us a united nation. |Year of Publication:|| |Country of Origin:|| This book will be shipped in 2 days’ time. The time taken for you to receive the book after it is shipped will depend upon the mode you choose, while completing your purchase. The rates applicable for each mode are different. You will be informed after the order is shipped. Shipping costs depend on the mode chosen, the weight of the item, and the distance it will travel to reach its destination. Shipping costs will be charged depending on the weight of the entire purchase (if more than one book is purchased). The same shipping mode will apply to all products in such a case.
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Coping with the diagnosis of breast cancer can be particularly difficult, emotionally as well as practically. While you might feel stressed and upset about the disease, you might also be extremely worried about the treatment costs and life post breast cancer treatment. Remember that it's perfectly normal to have anxiety about the various treatments, especially if you've never had it before. Whether you opt for surgery, chemotherapy, radiation or hormone therapy, they all come with a fair share of side effects and thus, you must be prepared to face the consequences in your battle to fight cancer. You can also find more details on breast cancer treatment through sites like ICRMC. These some simple and effective tips to help you cope with breast cancer treatment: Stay Healthy During Treatment – It might be difficult or even seem impossible to focus on anything other than the treatment during cancer. However, it is important to stay fit and live well during your treatment. Good nutrition is an extremely vital part of cancer treatments. Make sure you eat well, keep fit and maintain a positive attitude as much as possible during this time. Fighting Fatigue – One of the most common and depressing side effects of breast cancer treatment is fatigue, where you feel a sense of tiredness all the time. Take small 30 minute naps from time to time rather than a longer nap. If you rest too much in the daytime, it might lower your energy levels even more. Sleeping Well – A good night's sleep will help you cope the next day much better during your treatment sessions. Try to get at least 7-8 hours of sleep every night. If you're having trouble sleeping, speak to your doctor to adjust your medications. Avoid caffeine, chocolates or late night exercise to make sure your body gets the rest it needs.
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[June-2022]Instant Download Braindump2go 350-401 Exam Dumps 350-401 814Q[Q794-Q808] June/2022 Latest Braindump2go 350-401 Exam Dumps with PDF and VCE Free Updated Today! Following are some new 350-401 Real Exam Questions! What is the recommended minimum SNR for Voice applications for networks? Which two results occur if Cisco DNA center loses connectivity to devices in the SD-ACCESS fabric? (Choose two) A. All devices reload after detecting loss of connection to Cisco DNA Center B. Already connected users are unaffected, but new users cannot connect C. User connectivity is unaffected D. Cisco DNA Center is unable to collect monitoring data in Assurance E. Users lose connectivity Witch two actions provide controlled Layer 2 network connectivity between virtual machines running on the same hypervisor? (Choose two.) A. Use a single trunk link to an external Layer2 switch. B. Use a virtual switch provided by the hypervisor. C. Use a virtual switch running as a separate virtual machine. D. Use a single routed link to an external router on stick. E. Use VXLAN fabric after installing VXLAN tunneling drivers on the virtual machines. Which free application has the ability to make REST calls against Cisco DNA Center? A. API Explorer B. REST Explorer Refer to the exhibit. R1 and R2 are directly connected, but the BGP session does not establish. Which action must be taken to build an eBGP session? A. Configure ip route 188.8.131.52 0.0.0.0 192.168.12.1 on R2. B. Configure neighbor 192.168.12.1 activate under R2 BGP process. C. Configure neighbor 184.108.40.206 remote-as 65002 under R1 BGP process. D. Configure no neighbor 192.168.12.1 shutdown under R2 BGP process. If AP power level is increased from 25 mW to 100 mW. what is the power difference in dBm? A. 6 dBm B. 14 dBm C. 17 dBm D. 20 dBm Which signal strength and noise values meet the minimum SNR for voice networks? A. signal strength -67 dBm, noise 91 dBm B. signal strength -69 dBm, noise 94 dBm C. signal strength -68 dBm, noise 89 dBm D. signal strength -66 dBm, noise 90 dBm Which two methods are used by an AP that is typing to discover a wireless LAN controller? (Choose two.) A. Cisco Discovery Protocol neighbour B. broadcasting on the local subnet C. DNS lookup cisco-DNA-PRIMARY.localdomain D. DHCP Option 43 E. querying other APs Refer to the exhibit. Which router is elected as the VRRP primary virtual router? A. Router B B. Router D C. Router C D. Router A Refer to the exhibit. Which command allows hosts that are connected to FastEthernet0/2 to access the Internet? A. ip nat inside source list 10 interface FastEthernet0/1 overload B. ip nat inside source list 10 interface FastEthernet0/2 overload C. ip nat outside source list 10 interface FastEthernet0/2 overload D. ip nat outside source static 220.127.116.11 10.10.10.0 overload Which A record type should be configured for access points to resolve the IP address of a wireless LAN controller using DNS? By default, which virtual MAC address does HSRP group 30 use? Which activity requires access to Cisco DNA Center CLI? A. provisioning a wireless LAN controller B. creating a configuration template C. upgrading the Cisco DNA Center software D. graceful shutdown of Cisco DNA Center Which NTP mode must be activated when using a Cisco router as an NTP authoritative server? C. broadcast client Refer to the exhibit. An engineer must configure an ERSPAN tunnel that mirrors traffic from linux1 on Switch1 to Linux2 on Switch2. Which command must be added to the destination configuration to enable the ERSPAN tunnel? A. (config-mon-erspan-dst-src)# origin ip address 172.16.10.10 B. (config-mon-erspan-dst-src)# erspan-id 172.16.10.10 C. (config-mon-erspan-dst-src)# no shut D. (config-mon-erspan-dst-src)# erspan-id 110 1.2022 Latest Braindump2go 350-401 Exam Dumps (PDF & VCE) Free Share: 2.2022 Latest Braindump2go 350-401 PDF and 350-401 VCE Dumps Free Share: 3.2021 Free Braindump2go 350-401 Exam Questions Download: Free Resources from Braindump2go,We Devoted to Helping You 100% Pass All Exams!
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In the month of February, we will be running a special called Doctors with a Heart. It’s important for us to give back to the community that we serve. We have at least 3 events each year in which we donate to a charity. Past recipients have been Open Doors for Youth, CAER Food Shelf, and Feed My Starving Children, to name a few. We have been running the Doctors with a Heart program for the past 12 years. We offer new patients a great deal on their first visit, and since 2012, we have donated their payment to a charity that hits close to home for us, the Cystic Fibrosis Foundation. Specifically, for Team Dylan. Dylan Mertz is our twenty-two-year-old patient who has been living with cystic fibrosis (CF) his entire life. Dr. Jeremy has had the pleasure of being his chiropractor since Dylan was 8 years old. He has overcome so much, as he complies with all that is asked of him to keep him healthy. He takes nearly 60 pills a day, does an hour of chest physiotherapy (using a vest), and has to take inhaled medications as well. He has always stayed active and wants to be sure he stays healthy for when a cure comes. One of the ways he stays healthy is with regular chiropractic care. Most people think of chiropractors as back and neck doctors, but really, we’re concerned with how your nervous system is working. We just use your back and neck to access your nervous system. Your nerves control everything in your body from your muscles, organs and glands to your blood vessels. So, if your nerves aren’t functioning right, the rest of you won’t work right. It is especially important for someone like Dylan, dealing with a genetic disorder, to have an optimally functioning spine and nervous system. This will allow his body to focus on fighting cystic fibrosis (CF). We recently had the opportunity to catch up with Dylan’s mom, Pam, who gave us an update on him! “Dylan continues to enjoy thriving as a 22-year-old in his fourth year of college. He recently took a pulmonary function test and scored 111% of normal. As an adult, this is not an easy task! He has also gained some weight recently, using some nutritional advice from Dr. J. This made his dietician very happy!! You see, with CF, it is very hard to keep weight on, and CF patients must consume 4000-5000 calories a day just to maintain weight. This is due to the malabsorption that is a part of CF, as well as the extra calories burned in the simple act of breathing. Every breath takes more energy for CF patients than for you and me. Dylan continues to use Ideal Health to optimize his health and well-being. He has received chiropractic adjustments regularly since early childhood, and also enjoys acupuncture, and some physical therapy as needed. With his health care team, he feels able to continue to manage his cystic fibrosis well. This allows him to focus on the things he is discovering that he loves to do! He is now an avid waterfowl hunter, being located in Grand Forks, near the waterfowl flyway. He is also enjoying “clean” cooking and is often hired by friends and acquaintances to prepare meals for them. As he continues his studies in public policy, he is keenly aware of the underdog, and the underserved. He has a passion for pursuing a career in advocacy and it will be exciting to see where he lands! He has a bright future and the amazing team at Ideal Health has helped him achieve this level of wellness. We, as a family, are so grateful for this Ideal Health family to help us navigate CF and provide peace of mind, knowing Dylan is able to pursue his dreams like any other college student. By helping the CF Foundation, we are able to continue to do research that will help all CF patients with the needed antibiotics, therapies and hopefully that cure that we all pray for. Until it’s done, we continue to raise awareness and are so grateful that Ideal Health is a part of Team Dylan! We are blessed!” We are honored to help this amazing family! Please visit https://www.cff.org/ for more information about cystic fibrosis and the great work being done to discover treatments and cures.
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World travel is not only becoming more accessible- it’s also becoming more convenient. With the help of evolving technology international students are able to find the opportunity to study overseas, along with resources to help them during their journey. One great (and sometimes free) resource that all international students should take advantage of are apps. Take a few moments and check out these apps you need as an international student- you’ll be happy that you did! City Maps: City maps are a necessity when navigating through a new city! However, paper city maps aren’t the most practical solution and are becoming a tool of the past. By the time you find a paper map in the city you’re visiting, you’ll more than likely have already visited every block. Also, paper maps are not the most environmentally friendly option. What’s an avid traveler like yourself to do in a new city? Get a map app! Currency Conversion: Although you will get used to the currency exchange rate quickly in the country you are studying in, when you travel to neighboring counties that use different currency you might need some help. You can either use the pre-smart phone technique of having a conversion “cheat-sheet” in your pocket at all times, or just get a currency conversion app. Wi-Fi finder: Having internet access is as important (if not more) as having an extra pair of socks when traveling. Enjoy the sites around you and get an app that will find the Wi-Fi for you. Translation: Every traveler has been stuck in an awkward language barrier conversation. Next time that happens make sure you can put an end to it right away. This translation app can help. Camera: Your photos will spark memories of your travels years down the road. Get a photo app that will help you take great shots, edit and keep it all organized. Health Insurance: Although an insurance app isn’t as exciting as the other ones, it’s important to have if you become ill or injured. You can find a doctor and have instant access to a helpline.
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ARCHITECTURAL SHOP DRAWINGS It is very important for every contractor to have the right architectural shop drawings. The shop drawings are very consuming, and take up loads of time to create. Shop Drawing Services, who have the knowledge and know-how to draw proper drawings. In order for one to construct a building, we shall need to have the right plan. This will make it easier for us to know all the plumbing, places of the windows, the electrical lines, the steel lines, and the elevator details etc. The accuracy needs to be exact and in accordance with the dimensions of the building. In simple terms, all the engineers, the contractors and other technicians involved in the construction of the building, they should have an easier time with the interpretation of these details. The right architectural shop drawing procedures need to be filed in the right channel, and this will lead the coordination of the contractor, the engineer, the architect, the plumber and electrician. Shop Drawings need to have the proper records, the design of the building and the estimated descriptions. The parties involved to architectural shop drawing will include the contractor, the supplier, the manufacturer, the engineer, the installer and the architect. They have to carry out tests, and measurements, which will lead to the right development and plan of the building. You cannot order windows, when you do not know all the description, and the elevations that is needed. There are different submittals, which are needed during the architectural shop drawings will include the ones, which were in existence during the time of the construction contract. The details of the architectural shop drawings will include the stability, safety, appearance, building code, function, and other additional details. In order for the architect to apply the drawings, they shall need to work with the engineer, the manufacturer, the suppliers, and the listed code of conductors. In case there are issues, the corrected drawings are sent back to all the involved parties. Shop Drawing Services ready to work with you. Please contact us for any questions.
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Project Management in Pharma and Biotech In our working environment, the importance of project management is steadily increasing. In the healthcare sector including the pharmaceutical, biotech and medical device industries, a substantial increase in project-oriented jobs is seen. Efficient project management is key to organizing complex cross-functional environments and achieving goals within time and budget. Among different sectors, the pharmaceutical, biotech and medical device industries stand out as they are highly regulated. Hence, special attention needs to be paid in order to fulfil the demanding regulatory and quality requirements. Many graduates in the STEM subjects, aiming at a career in industry, will work in or lead project teams. However, academic education pays little attention to these topics and academic research projects are very different from an industrial project setting. Hence, graduates are generally not familiar with the requirements when transitioning into industry. This workshop is specifically designed to students, recent graduates and other interested persons with no or little experience in an industrial project setting. We will start by identifying the specific demands and requirements of the pharmaceutical and medical device industries. Specific terms and principles of project management will be introduced, and we will discuss different project management approaches and compare them (e.g. waterfall vs. agile methods). Diving deeper into project management, we will discuss in several interactive examples how projects are set up and managed including the definition of scope, cost, timelines and required resources. Our results will be laid down in project documentation such as a project management plan. Project communication and the management of involved stakeholders – two areas, which are often neglected in projects – will also be part of this workshop. Finally, the participants will learn how to ensure project quality and identify and mitigate occurring project risks. During the whole workshop, the focus will be put on the specific characteristics of project management in a highly regulated environment and the future of project management will be outlined. Enough time will be planned to answer questions and give more in-depth explanations on real-life project situations. At the end of the workshop, participants will have gotten a good impression of the requirements and skills needed to manage projects in a pharmaceutical or medical device setting. This will represent a clear advantage for students applying for a job in project management and facilitate the transition from academia into industry. About the workshop leader: Dr. Fabian Muttach studied Molecular Biotechnology at Heidelberg University with a focus on drug discovery. After graduating in 2014, he moved to the University of Münster where he obtained his Ph.D. in biochemistry in 2018. His research interests focused on establishing enzymatic cascade reactions for the precise modification of nucleic acids. Afterwards, Dr. Fabian Muttach worked for Thescon, a medium-sized company offering consulting services in all areas of GxP-compliance, process and project management. During his work he gained in-depth experience in quality and project management of medium-sized companies as well as multinational corporations in the pharmaceutical and medical device industries. In 2021, Dr. Fabian Muttach joined Boehringer Ingelheim as a process manager. He is now responsible for various projects in the area of global pharmaceutical master data management. each from 18:00 - 20:00 pm
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- Most employee benefits we receive from our employers are provided “tax free.” Why? - What percent of Total Compensation does the average employer pay for benefit plans? What percent of payroll does your employer pays for your benefits? - Explain the difference between a defined benefit retirement plan and a defined contribution plan. Do you participate in either or both of these plans with your employer? Explain. - What kind of health care plan do you participate in? How much is your monthly premium? How much does your employer pay monthly? - Has your employer taken any action to help employees have a greater appreciation for their Employee Benefits? If yes, what specifically has been done? - Has your employer taken any action to help and encourage you to be a better health care consumer? If yes, what specifically have they done? If you are not currently working, please answer questions 1 through 3 above and the following: - What are the most common benefits that organizations provide? - What are 2 or 3 of the trending benefits that were not common a few years ago?
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I recently took an online class through my friend and fellow writer Michael Knost on body language, and wanted to share some of the highlights that I found helpful. This was a topic I knew some about from other writing sources, but his class really brought everything into prospective for me. Body language is essential in creating believable characters. It’s the subtle things like a smile in just the right place of a conversation, or a small touch of the hand that can change the whole way a reader perceives a character. When you show a character through their body language, you are allowing the reader to size up the character without spoon feeding information that might push the reader from the story. The reader wants to feel intelligent as he or she comes to their own conclusions. It’s the writer’s job (you) to be invisible enough to help lay out the signs or clues that get the reader to where you want them to go. Check out some of these statistics… 55% of communication consists of body language 38% is expressed through voice 7% is communicated through words Yeah, I was kind of shocked by the only 7% is communicated through words. Kind of made me feel small and unimportant with all my writing, which then made me realize that it’s all in how you express those words. That’s the key ingredient to really great writing. So my next thought was… how do my own characters express themselves? There are 4 major ways for a character to use body language to express themselves… - Facial Expressions - Body Posture What are the eyes of your character saying? Is your character fidgeting from boredom or restlessness? Is your character sitting forward to soak up everything another character is telling them? Or is your character in someone’s face for something that made them angry? Also consider this… does your character’s actions match their words? Readers will believe body language and tone over what someone says. If a character says they’re open to a new idea, but crosses their arms or turns their body away, what the reader really sees is a character who is closed and rejecting the message, but not willing to admit the truth. This sort of “mixed signal” can be used to add to the character, or story. It can also take away from the character and story, if not done correctly. When using body language it usually helps to build it up to a series of actions, because some body languages (like smiles, fidgeting, or no eye contact) can mean several different things. Writers should give about 5 clues within a scene to show context of an emotion (through body language) without coming out and saying it. This will help lead the reader to make his own conclusion. Body language is your character. Make sure that that all body language is important, if it isn’t, cut it out. Also get rid of overly used gestures, or body language like… she sighed or he winked. Find new or better ways for your character to express themselves. Remember that too much of a good thing can tip your hand to make the writer visible to the reader. Great writers disappear as their story comes alive.
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OR WAIT null SECS We're all familiar with traditional pills and medicines, but how about medicated chewing gum? Marc Ribe of Cafosa Gum explains how APIs can be incorporated into a novel dosage form that can aid patient compliance. Cafosa's excipient Health in Gum is a mix of ingredients to which APIs can be added. How are APIs added to create a novel dosage form? Marc RibeTraditionally, medicated chewing gum has been formulated and manufactured using hot mixing and extrusion procedures, which involve specific equipment that most pharmaceutical companies are not familiar with. Moreover, the use of heat in this process prevents many APIs from being considered because of their sensitivity to high temperature levels. Our Health in Gum is a homogeneous powder excipient produced using proprietary technology. It is a combination of gum base, softeners and polyols that enables formulation and dry mixing with the API to produce chewing gums by direct compression. Medicated chewing gum is an interesting option for pharmaceutical companies looking to differentiate themselves by introducing products that are more attractive to consumers, but that possess the same efficacy as other dosage forms. In particular, the technology is useful to look at in light of the fact that many people dislike swallowing tablets or other medicines. Chewing gum is also a convenient drug delivery form because it does not require water intake. In addition, it offers some well-known inherent benefits for oral health, or as a stress or weight management aid, and can be combined with the therapeutic action of an active ingredient to give great performance and improve compliance for consumers. Importantly for pharma companies, medicated chewing gum is an accepted dosage form in current Pharmacopoeias and the ingredients are compliant with different monographs. How are common API problems, such as taste masking and solubility, affected by using chewing gum? Most active ingredients have a bitter and unpleasant taste and in the case of chewing gum, taste masking is of great concern because the residence time in the mouth is much longer (20–30 min) compared with other dosage forms. However, similar strategies seen in other oral dosage forms can be used; combining flavours and intensive sweeteners has been successful in some cases, while other solutions may require ion exchange resins or complexing agents (e.g., cyclodextrins). API solubility can be influential in the dissolution rate from the chewing gum matrix. We know that highly soluble APIs are released completely and much faster than slightly or poorly soluble APIs, which require longer chewing times. In some cases, only a percentage of the total drug content is made available. Again, we believe that solubility enhancers used in other dosage forms can be used to good effect in medicated gum to promote higher dissolution of poorly soluble actives. At our company, we’ve worked with poorly-soluble APIs and found that, in some cases, the gum should be chewed for 30 minutes or more to get a 50% release of the APIs. This isn’t like the sustained release of a normal tablet, which can take 3–4 hours in the digestive tract. For pharmaceutical manufacturers, what are the benefits of packaging APIs in this way? What types of APIs in particular would benefit from being incorporated into chewing gum? The advantages are that pharmaceutical companies do not have to invest in extra chewing gum equipment in their facilities because our product range uses standard direct compression technology. Chewing gum stability is also very good because the humidity content of the powder is low — much lower than traditional chewing gum made by extrusion. In particular, APIs that are heat and humidity sensitive are good candidates for formulation into medicated gum. What are the specific manufacturing challenges associated with incorporating APIs and chewing gum? We still have a few challenges to overcome with the technology. The main challenge is increasing the potential dose content of a given API in medicated chewing gum. Given that a chewing gum dosage form must have a minimum gum base content to be chewable, this limits the total API content to a maximum of approximately 200 mg in a total chewing gum piece of 1-1.2 g. However, we expect to be able to increase this minimum in the coming 1–2 years with new versions of the excipient. What kind of future do you predict for this technology? Do you think uptake in the pharma industry will increase or will it always remain a niche dosage form? We are pretty sure that more pharma companies will adopt this technology as a way to differentiate their product range in the current competitive landscape. New drug delivery systems are also gaining greater importance as a way to improve consumers´ compliance and preferences. Health in Gum is a good way to achieve this. Today, chewing gum is still perceived as a confectionary pleasure by consumers, but its visibility as an attractive, high-valued drug delivery system is increasing. Major successes have been seen in the nicotine replacement therapy gum market, and several new products have also been developed in diverse categories such as analgesics, digestive, cough and cold medicines, and antiallergics. New gum medications in weight management, energy supply or oral care categories are also beginning to appear in pharmacies. One issue to consider with medicated chewing gum is over consumption. Medicated chewing gum is a medicine and must be considered as such. This is reinforced with packaging, for instance, which is much more medical and contains a leaflet. Theses successes make me really optimistic that medicated chewing gum will progressively leave its current niche category to become a solid drug delivery system in the coming years. Gum technology has evolved very much in the recent years and we are very confident that these breakthroughs can be transferred into the pharma industry.
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In his book, The Pursuit of God, A. W. Tozer tells us that belief in Christ is really “the gaze of the heart at God." This practice of inwardly gazing upon God is so important in bringing Christians into a deeper relationship with Him and will, in turn, be the key to bringing a spirit of unity to the Church. Tozer says, "Has it ever occurred to you that 100 pianos all turned to the same fork are automatically turned to each other? They are of one accord by being tuned not to each other, but to another standard to which one must individually bow. So one hundred worshipers meeting together, each one looking away to Christ, are in heart nearer to each other than they could possibly be were they to become 'unity' conscious and turn their eyes away from God to strive for closer fellowship...The whole Church of God gains when the members that compose it begin to seek a better and a higher life." When we are in harmony with God, and with one another, we attract the attention of heaven. We become like a giant magnet pulling heaven to earth. Our corporate prayers and worship, lifted in unity, draw the very presence of the Holy Spirit into our midst, along with angels who want to join us. We can read about this happening in Acts 2:1-4. "Now when the day of Pentecost had fully come, they were all with one accord in one place. And suddenly their came a sound from heaven, as of a rushing mighty wind, and it filled the whole house where they were sitting. Then there appeared to them divided tongues, as of fire, and one sat upon each of them. And they were all filled with the Holy Spirit..." (NKJV) The apostle Paul recognized the joy that a spirit of unity in Christ brought to the Lord, and so he encouraged the people of the church in Philippi in this way: "Therefore if there is any consolation in Christ, if any comfort of love, if any fellowship of the Spirit, if any affection and mercy, fulfill my joy by being like-minded, having the same love, being of one accord, of one mind. Let nothing be done through selfish ambition or conceit, but in lowliness of mind let each esteem others better than himself." (Philippians 2:1-3 - NKJV) Our time here on earth is meant to sanctify us so that we are like Christ Jesus. We must learn to follow His example in order to become like Him. Therefore, the inward gaze of our hearts upon the Lord is key to our transformation. As we see who Christ is we become more like Him. We all play a part in bringing the Body of Christ into a spirit of unity--One Accord! Jesus came to show us the face of God. He cared deeply for those who believed in Him and prayed for them and us before His death. "I will remain in the world no longer, but they are still in the world, and I am coming to you. Holy Father, protect them by the power of Your name--the name You gave to me--so that they may be one as we are one...Sanctify them by the truth; Your Word is truth...For them I sanctify myself, that they too may be truly sanctified...I pray also for those who will believe in me through the message, that all of them may be one, Father, just as you are in me and I am in you...I have given them the glory that you gave me, that they may be one as we are one." (John 17:11, 17-22) Let us make our prayer like the Psalm that David wrote: "One thing I ask of the Lord, this is what I seek: that I may dwell in the house of the Lord all the days of my life, to gaze upon the beauty of the Lord and to seek Him in His temple." (Psalm 27:4) Our gaze upon our Savior fine tunes us so that we are in harmony with Him and will be in harmony with others in the Body of Christ who are also gazing at His beauty. This is when heaven comes to earth! Let it be, O God! Joan E. Mathias
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The global transcranial magnetic stimulator market is accounted for more than US$ 900 Mn in the year 2019 Reports and Insights (R&I) has published a new report titled, “Transcranial Magnetic Stimulator Market: Opportunity Analysis and Future Assessment 2022-2030” Global transcranial magnetic stimulator market, By Type (Deep Transcranial Magnetic Stimulator (dTMS), Repetitive Transcranial Magnetic Stimulator (rTMS), Others), By Application (Alzheimer’s Disease, Depression, Parkinson’s Disease, Epilepsy, Others), and By Region (North America, Europe, Asia Pacific, Latin America, Middle East, & Africa) is expected to grow at a significant CAGR for the period between 2022 and 2030. In 2019, the global transcranial magnetic stimulator market is accounted for more than US$ 900 Mn and expected to grow at a significant CAGR of 8.4% during the forecast period of 2022 to 2030. As per the report, the rising prevalence of neurological disorders among the population such as Alzheimer’s and Parkinson’s disease (PD) across the world is majorly contributing to the growth of the global transcranial magnetic stimulator market. A medical non-invasive procedure using magnetic fields to stimulate nerve cells in the brain in order to cure the symptoms of depression is commonly known as transcranial magnetic stimulation (TMS). The transcranial magnetic stimulator is also in enhancing the signs of other neurological disorders. Owing to which, the global transcranial magnetic stimulator market is expected to grow positively in the near future. The growing geriatric population across the globe is also contributing to the rise in count of patients with neurological disorders, thus giving a positive push to the growth of the global transcranial magnetic stimulator market. Notably, several different methods of brain stimulation are available including electroconvulsive therapy and deep brain stimulation techniques, however, currently, the transcranial magnetic stimulation technique is the most widely adopted method for brain stimulation across the world owing to the numerous benefits of transcranial magnetic stimulation (TMS) such as it does not require anesthesia, it is non-invasive, and well tolerated. Moreover, the hectic and desk-bound lifestyle of the population across the world in recent times is also causing serious disorders among the population such as stress, hypertension resultantly leading to depression, which subsequently propels the growth of the global transcranial magnetic stimulator market. Additionally, in 2008, the FDA approved transcranial magnetic stimulation (TMS) for the treatment of depression, which also acts as a positive aspect for the rapid growth of the global transcranial magnetic stimulator market. In addition to that, the supportive remuneration and new and technologically enhanced products brought in by key manufacturers of the global market such as neuro-navigating stimulators is also augmenting the growth of the global transcranial magnetic stimulator market. However, few factors such as clinically proven high efficiency of electroconvulsive therapy for the treatment of clinical depression and growing number of patients accepting the therapy may hamper the growth of the global transcranial magnetic stimulator market. R&I Study identifies some of the key participating players in the transcranial magnetic stimulator market globally are Axilum Robotics, Mastigm, Nexstim plc, Neuronetics, Inc., Brainsway Ltd., and TMS Neuro Solutions. About Reports and Insights: Reports and Insights (R&I) is committed to provide deep insights that serve as a creative tool for the client that enables it to perform confidently in the market. At R&I we adhere to the client's needs and regularly ponder to bring out more valuable and real outcomes for our customers. We are equipped with a strategically enhanced group of researchers and analysts that redefines and stabilizes the business polarity in different categorical dimensions of the market. Reports and Insights (R&I) For Sales Query: [email protected] For New Topics & Other Info: [email protected]
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Geology and Creation | Book | Don Deyoung | CRSID: 0940384299 $12.00 Geology and Creation presents non-technical answers to 100 of the most-asked questions in earth science. DeYoung shows that geology, properly interpreted, supports a recent creation and catastrophic events such as the global flood of Noah. topics include: What is a living fossil? How do new rocks appear in farm fields? Was there an Ice Age? Is the earth hollow? Why is the Dead Sea so salty? The convenient question-and-answer format makes it practical in the classroom and ideal for homeschooling. Also included are sources for in-depth study, a glossary, and Scripture and subject indexes. Physical Science and Creation: An Introduction | Book | Don B. DeYoung | CRSID: 0940384191 $5.00 Physical Science and Creation: An Introduction | Book | Don B. DeYoung | CRS. . Dr. DeYoung presents not only the classical subject matter of physical science (the building blocks of nature, motion and forces, gravity, energy, and light), but he also touches briefly on more modern topics such as radiometric dating, quantum theory, the uncertainty principle, and relativity. Showing all 4 results
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Next Monday morning, the polls open that begin the process of deciding who will become the two main contenders in the 2016 US presidential election. Can you guess who they'll be? Microsoft can. The company has a tool called "Bing Predicts," tied to Microsoft's search engine (Bing). While the tool can be used for a variety of different predictions, in this instance it's looking at searches, polls, and prediction markets to determine who will win the presidential primaries. Before you write this off solely as a marketing gimmick, you should know that the tool has a pretty impressive track record — with politics in particular: - Bing Predicts was spot on with the outcome of the 2014 Scottish independence referendum, and it correctly predicted the outcomes for all of the 15 games in the knockout round of the 2014 World Cup. - In terms of US politics, Bing Predicts did pretty well in predicting how the 2014 midterm elections would go. It was 97% accurate in predicting the outcome of Senate races, 96% accurate predicting the outcome of House of Representatives races, and 89% accurate in predicting the outcomes of races for governor. So, how do the current crop of candidates stack up in the upcoming primary elections to determine the representative from each party? Here's what Bing Predicts projects for the first four contests:
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From the glacial boulder that marked the trailhead, our path wove between lodgepole pines and along the canyon’s rocky rim. Twelve hundred feet below, the Yellowstone River flowed steadily on, a blue ribbon anchoring rugged rock walls. We stopped when we saw it—a slim streamer shimmering down the canyon wall across from us: Silver Cord Cascade. That’s what we’d hiked in for. Jaime reached into his pack and pulled out breakfast. Somehow, he’d managed to transport two cups filled with our house granola and a miraculously-unspilled container of cream. If I’d been responsible for packing our food in, we’d have breakfasted on apples and trail mix or packaged bars. But I wasn’t on breakfast duty. Jaime was. And not only does he like to surprise, he’s also a fan of good food with great scenery. Side by side, we leaned against a lichen-covered boulder, content with our view, our breakfast, and the beginning of our day. A Little About Lichen I’m embarrassed to admit this, but just as it took decades for me to develop a love of hiking, it took me years to look into Yellowstone’s lichen. I’m guessing some of you aren’t familiar with lichen, either. Some of its sort bear surprising names: Fairy Barf and British Soldier, for example. All result from two dissimilar organisms (usually fungus and algae) coming together as something new. Our hike to the Silver Cord Overlook had been nearly a year in the making. Not that it was so tough we needed to train. It wasn’t. But at a thousand miles from our home, we needed to plan. The making of that hike began as most of our adventures do. I said a version of, “I feel a visit to Yellowstone coming on” and Jaime, with zero hesitation, answered with something like, “When shall we go?” Then we launched into a series of questions to sort out what we wanted to do, see, and experience. My skills run along the lines of awareness. I know that just as we have a recurring need to be refueled by food, we both function best when we regularly spend a good stretch in the wilderness. The wilderness that suits us best is in the Greater Yellowstone Ecosystem. Jaime’s skills tend toward the practical. He’s a master at securing impossible reservations and distilling down Yellowstone’s thousand miles of trail to a few options matched to our preferences and abilities. (And I must never forget his willingness to haul in the makings of a soul-satisfying breakfast when RX bars would fill the fuel requirement.) Together, we’re like that lichen covering the boulder. We are dissimilar beings—more dissimilar than we knew when wed. He brings who he is to the life we’re creating together. I bring who I am. And from that, God is continually making something new. Here’s the truth: Our assets are different–completely different–but compatible. That’s what makes them assets. Jaime’s got more strength and skill for an adventurous life. He knows how to get it done. What I have is a grasp of how we’re doing—heart, soul, mind, and strength, along with the foresight to say, “Let’s . . .” Without me, Jaime wouldn’t look far enough into the future to make it happen. Without him, I’d stick to the easiest trails and sleep only in hotels. Our life is better together when we let our strengths fill in for one another’s deficits. Lichen life is good. Fostering an Adventurous Life, Lichen-Style Some solitary adventure may be good for the soul but we were made for life together. Just two chapters in, God declared that it’s not good for man to be alone. Whether with family, a friend, or your spouse, adventure is better together. You’re here. You’ve got some interest in fostering an adventurous team. Maybe you have someone you’d like to bring along with you. Maybe their feelings about the subject are hesitant or even negative. Pause a moment. Prepare for your next step by reflecting on these questions: - What are your assets when it comes to fostering an adventurous life? (Here’s a short list for a starting point: Mad Boy Scout skills? General know-how? Desire? Planning? Timing? Awareness? Other?) - What assets does your partner possess? (Use the same list as above, if you need help getting started.) - How can you bring these assets together to take your next (or first) step toward fostering an adventurous life? Let us know what you discover or what your next step will be. We’d love to hear. Happy trails ~
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Saplings Classroom, Ages 18 months – 3 years Our Toddler Program introduces children to a Montessori environment specifically created to nurture the individual at the tender age from 18 months to 3 years. In this prepared environment, children access experiential learning materials that leave concrete impressions and create a foundation for the development of language, mathematics, and cultural awareness. Young learners develop motor skills necessary for independence, care for oneself, and care of the environment. Recognizing that the toddler years are one of the most beautiful and delicate phases in the young child’s development, we encourage independence while supporting social and emotional growth. We teach peaceful conflict resolution, with the hope of creating a foundation of confidence and the value of cherishing all living things. The Montessori Philosophy to “follow the child” allows us to find teachable moments within the curriculum. The toddler experiences liberty of choice within a daily structure that will ultimately prepare him or her for a Montessori Preschool education.
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but attention seeking using significant remarks is unhealthy seeking attention by doing this…Pewdiepie Betterhelp Reddit… may be done out of fear and some believe it has fun with other people’s emotions some individuals consciously or unconsciously search for attention however may not know that they are taking part in attention-seeking habits individuals might say or do things to get attention from others on purpose for instance an individual might look for recognition for previous accomplishments deliberately make a questionable statement to get a reaction or inform stories about themselves while stretching the truth to get compassion or appreciation from others an individual may act like they need assist with something to get assistance from someone even if they know what to do there are numerous possible reasons that somebody would take part in this behavior people might feel alone envious or lack self-confidence somebody feeling jealous may feel threatened when somebody else is the focal point as a result they will alter their behavior to end up being the brand-new focus others might have a personality disorder such as borderline personality disorder or egotistical personality disorder a person with narcissistic personality disorder looks for adoration from others without empathy they might benefit from somebody to benefit themselves act conceited or neglect others sensations or needs other causes might consist of injury stress and anxiety or other mental health concerns a person may engage in attention looking for habits due to the fact that it makes them feel excellent engaging in conduct that seeks others attention might affect how they think of you in the long term it can make their sensations about you change or lessen people often look at this type of habits as manipulative if you recognize that this habits is repeating you may find it useful to deal with a therapist or mental health professional such as those at much better help when left unaddressed it could end up being hazardous treatment alternatives include recognizing unhealthy behavioral patterns and understanding the very best method to your emotional needs discover how to construct self-esteem spend more time listening to others before you speak examine your habits and acknowledge it Talking about personal matters can be hard to do even when talking to somebody that you know well. That can make it feel harder when talking to a complete stranger. It’s your therapist’s objective to assist you make progress in the areas that you’re fighting with. And in order for them to do that, they need you, to be sincere with them. This doesn’t imply that you need to pour out every detail of your life, however ensure that the information you are sharing is true. Attempting or lying to misinform your therapist will make it harder for them to assist you. It is fine to speak if you feel uneasy, however try to be honest. Pewdiepie Betterhelp Reddit
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Yoga For Beginners is the best gentle practice to help you get a healthy body, full of energy and a relaxed mind. Unlike other disciplines that are fast and powerful, yoga needs to be practiced slowly and deeply. Purify the mind while practicing and feeling the change of the body. The application is suitable for everyone, male and female. We build yoga programs from beginner to advanced that both beginners and skilled people can practice. The completely free yoga poses help you have interesting sessions, condition your body, lose weight and get a healthy slim body. The great things that YoMaster - Yoga For Beginners gives you: ★ Smart simple interface easy to practice ★ Complete set of basic yoga exercises ★ Save your workout progress ★ Build many rich programs ★ Daily practice reminder ★ Graph, body index BMI ✔️ Basic 30-day training program for beginners to help you understand and perform yoga movements easily. ✔️ Selection of programs specifically for you in the discovery section ✔️ Morning yoga: Practicing yoga after waking up helps promote the body's metabolism, helps you control weight, and improves the digestive system. Practicing yoga regularly in the morning will help you relax and focus better, helping you to have an active and effective working day. ✔️ Meditation: An indispensable technique in yoga, you can practice meditation anytime, anywhere, it will help you reduce stress and relax your body. This process of focusing on your breathing will help develop beneficial habits that put your mood and thoughts in a positive direction. ✔️ Bedtime yoga: It is an effective method for those who suffer from insomnia or who have poor sleep. When you practice yoga before going to bed, it will help your body relax, reduce muscle tension after a tiring working day, make you feel comfortable, and get a good night's sleep. ✔️ Practicing yoga not only relaxes the body but also helps you to improve yourself, that's why we also bring you a specific experience in each part when practicing yoga to help you have a toned butt. firm, flexible body movement, flat abdominal muscles, reduce stress, lose weight, keep fit, increase endurance, ... Choosing for yourself an application like Yoga For Beginners is to help you: - Train hard according to the program and you will have a perfect figure. - Improve flexibility, increase blood circulation when practicing yoga is a habit. - Become more confident with a healthy lifestyle. - Put the body into a state of relaxation, regulate the organs and strengthen the body's immune system. - Enhances focus at work and helps build strong muscles and bones for fun. - Prevents digestive problems when the body is stressed. - Improve the balance from which you will get a good night's sleep. 📌Help yourself perfect by downloading the app YoMaster - Yoga For Beginners now for the best experience.
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Zurich Instruments launches the SHFQC, its first qubit controller that can control, readout and perform fast feedback on up to 6 qubits. The SHFQC supports control and readout frequencies up to 8.5 GHz without the need for mixer calibration, and provides a wide and clean instantaneous bandwidth of 1 GHz. The SHFQC comes with 6 signal generator control channels and a single quantum analyzer readout channel, each of which can be controlled and triggered individually. Internal data and trigger distribution allow for fast feedback and a flexible and software-controlled reconfiguration of the qubit control system. The control channels can be programmed to generate complex gate sequences using efficient pulse-level sequencing in their arbitrary waveform generators (AWGs). The readout channel analyzes up to 16 qubits, 8 qutrits, or 5 ququads in real-time – time-staggered or in parallel. Thanks to the matched complex filters and tight integration with the control channels, both signal-to-noise ratio and readout latency can be optimized. Turnkey features such as fast acquisition of a resonator spectrum, and a high level of integration through LabOne, the LabOne QCCS Software, or the APIs and drivers for Python simplify and accelerate system characterization and tune-up as well as algorithm execution. The SHFQC integrates seamlessly into any new or existing Zurich Instruments Quantum Computing Control System and adds fast local feedback to existing error correction capabilities. Thus, a single SHFQC helps reduce the complexity of small qubit setups while also scaling up to systems of 100 qubits and beyond. To read more about the new Zurich Instruments SHFQC Qubit Controller, including the complete list of its specifications, visit www.zhinst.com and the SHFQC instrument page.To arrange a live demo, write to email@example.com.
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Live-streaming e-commerce is experiencing explosive growth in China and helping the country’s retail sector to recover from the impact of coronavirus, but experts have warned of widespread malpractice whereby fake traffic is purchased to boost viewer counts. A recent report by the South China Morning Post revealed the scale of the problem after talking to industry insiders, who said fake traffic is an ‘open secret’, not just in China’s booming live-streaming sector, but across global social media platforms too. “Fake traffic is not even an unspoken rule, but a widely known issue that not only the live-streaming sector but also the whole internet industry at home and abroad is trying to address,” said Zhang Dingding, an independent internet industry observer. “I don’t doubt the existence of fake users, but the key questions are who is behind the fake traffic,” he added. One answer is the role played by agencies that have been set up to manage and promote the live-streamed content produced by China’s growing community of online influencers. According to entrepreneur Huang Xiaobing, who ran a Tianjin-based agency until she retired recently, a common way of helping aspirant live-streamers gain popularity is to buy virtual gifts that trick algorithms into inflating viewer numbers. “Everyone in the industry does this one way or another,” she said, while adding that platforms themselves also sometimes artificially inflate numbers so it appears more people are watching. Parklu, a Shanghai-based influencer marketing platform, told the Post that live-streamers may be motivated to drive up sales numbers because of the commission they make from brands – they can be worth about 20% of sales. They may, for example, use bot-controlled accounts to buy products with their own money and return up to half of the items afterwards, pocketing the commission. The problem has certainly caught the attention of the Chinese authorities, which are tightening regulations for the industry. The Cyberspace Administration of China, for example, published draft proposals last month to prohibit the “fabrication or alteration of followers, views, likes, transactions and other traffic numbers” on live-streaming platforms. Meanwhile, the National Radio and Television Administration recently announced new rules, requiring live-streamers in China and their gift-giving fans to register with their real names. In addition, internet platforms have been told to set a cap on the gifts that each user can give. Sourced from South China Morning Post
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Nori is a kind of seaweed that has been consumed in Japan for generations. It’s commonly consumed raw or mildly steamed. Nori is also known as laver, laverwort, laver leaf, laver plant, laver root, laver root, sea lettuce, sea lettuce, seaweed, seaweed, sea vegetable, sea vegetable, sea vegetables, sea vegetables, sea vegetable, sea veggies, sea veggies, sea veggie, sea veggie, and seaweed. Nori is a member of the Laminaria family. The name “nori” comes from the Japanese word meaning “to wrap”. Are you a sushi connoisseur? Have you made the decision to make your own at home? Then you’re aware that having all of the components may be rather costly, especially if you live outside of Southeast Asia. We understand the fish and other meat, but nori sheets are usually rather costly. Why is it so costly? If you consider that one sheet is worth 6-8 sushi rolls, and you’ll get a pack in one sitting if you make a larger amount. So let’s look at what makes nori valuable. Nori is a type of seaweed that has been used for centuries in Japan. It’s often referred to as "the poor man’s caviar" because it’s so inexpensive. However, there’s a reason why nori is so pricey. Nori is extremely nutrient-dense and high in vitamins and minerals. It also contains a lot of protein and fiber. Nori is definitely worth checking out if you’re wanting to add some extra nutrients to your diet. Nori is often expensive due to the need for imports from Southeast Asia, and the nori manufacturing process is complex and requires a large amount of sea space. Japan is the world’s top producer of nori, followed by China. Good nori is made from good algae and is grown in clean, unpolished water before being converted into thin sheets of paper used in sushi. Let us look more closely at this because every element is connected to another. You need to grasp the full situation if you really want to know why nori is costly. Begin by focusing on the algae themselves. You can’t just utilize any ‘old seaweed around you; you’ll need a good crop. Pyropia yezoenis and Pyropia tenera are two different types of red algae. They are grown in large, dedicated water areas along the Japanese coast. The entire business focuses on safe and successful algae culture, with the actual production of dried nori sheets following. These are made using an ancient Japanese papermaking technique. The entire method is dependent on the biology of Pyropia algae. If a different type of algae is used, this will very certainly have to be changed. The first step in making nori is harvesting the alga. This requires taking care of the environment and using environmentally friendly methods. In order to harvest the alga, they use nets with small holes which allow the water to flow through while keeping the seaweeds safe. They then dry them on mats made of bamboo leaves. After drying, the seaweeds must undergo several processes before being ready to be sold. Almost all nori is produced in Southeast Asia, notably in Japan and China. Nori customized to your needs can be found in Korea, the Philippines, and even Canada. Not every producing country employs the widely used Japanese language (Pyropia). For example, China mostly employs luminaries, but others may employ Porphyra. Regardless of the type of algae used, the production technique is essentially the same, and the most majority of nori is still imported. This implies additional costs, and some of the items are original Asian brands, which raises the price even more (but ensures quality). In addition to the cost of the raw materials, there are additional expenses involved when importing nori. For example, shipping fees, customs duties, taxes, etc., are added to the price tag. This means that even though you might think you’ve saved money buying nori online, you haven’t actually done anything different than purchasing locally. If you live overseas, you should check whether or not local stores sell nori. When we talk about high-quality nori, what do we mean exactly? We’re talking about the best available product from the most reputable producers. There’s no point in paying for something inferior. If you buy your nori from a store, make sure that it has been harvested properly. Ask how long ago it was picked, where it came from, and ask questions like these. When you purchase nori online, you can usually see pictures of the product. Furthermore, if you want to know more details about the company behind the nori, look at their website. You’ll often find information regarding environmental practices as well as other important facts. We mean the water in which the algae have been produced when we say quality. You know the water isn’t always clean, yet algae still bloom there, if you have ever gone to the sea. Clean, uncontaminated water is essential for the growth of algae because in a nori sheet you will ultimately consume that. You may probably imagine what the algae are useful for nutrients in contaminated regions near sewage disposal stations. Seaweed must be grown in clean water near the beach. Furthermore, the product must be of high quality, which is usually the case during the first few harvests. Seaweed may be collected several times a year, around once every ten days. However, similar to tea leaves, the first is the most fragile, which is why thin nori sheets were created. The popularity of sushi continues to grow worldwide. It seems that people around the world enjoy eating this delicious dish. Sushi is now sold on airplanes, in supermarkets, and in restaurants everywhere. Even Mcdonald’s sells its own version of sushi rolls! However, despite the growing demand for sushi, many Westerners don’t understand why it costs so much. They assume that since they eat fish, they needn’t pay extra for it. Nori sheets are also costly since they’re nearly solely used for sushi and/or onigiri. In the West, both of them are still considered niche items. They’re more of a treat, reserved for rare events or a more upscale night out than your typical supper. As a result, nori is more expensive, and you can only get it in specialty stores or the Asian section of most supermarkets. Sushi is a popular Japanese dish that has been around for centuries. It’s also a favorite food among people who love to eat healthily. However, there are times when you want to enjoy sushi without eating too much fish. If you’re looking for alternatives to nori, here are some ideas that you might find interesting. You could use cucumbers instead of nori. If you slice one thinly enough, you won’t even notice any difference between the two. The taste is very mild, though, so you’d better add some flavorings such as soy sauce, sesame oil, salt, pepper, etc., depending on your preference. Instead of using nori, rice paper would work just fine. Rice paper comes in different sizes and thicknesses. Some types come with seasoning already added while others do not. To prepare rice paper, soak it in warm water until soft before rolling up your ingredients. This way, you avoid having to roll up raw nori sheets. Another alternative to nori is lettuce leaves. Lettuce leaves are usually available at grocery stores all over the country. They’re inexpensive and easy to make into wraps. Just cut them into strips and fold them like an envelope. Add whatever toppings you prefer: vegetables, meat, cheese, sauces, etc. In conclusion, we’ve discussed four reasons why nori is so expensive. We hope these tips will help you save money if you decide to buy nori from time to time. You’ll have no problem finding substitutes for nori because there are plenty of options. I hope this article helped you with all your food curiosities.
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Coalition urges commitment to balancing energy, conservation As President Barack Obama and Congress lay out their priorities for 2015 and beyond, a national sportsmen’s coalition urged leaders to keep in mind that the state of our public lands – and the fish, wildlife and recreation supported by them – is crucial to the state of our economy and national identity. Sportsmen for Responsible Energy Development noted that public lands help fuel the nation’s $646 billion outdoor recreation industry, including hunting and angling that contribute about $90 billion annually to the economy. Well-planned energy development that safeguards our waterways, air quality and fish and wildlife populations will pay dividends for generations to come, SFRED members said. SFRED representatives made the following responses to the president’s State of the Union address: "As the president said, it’s up to us to choose who we want to be in the decades to come. We can choose to build a future that leads the world in producing energy from new and better technologies and also preserves America’s natural heritage." Kate Zimmerman, the National Wildlife Federation’s public lands policy director. "The Obama administration showed it understood that a healthy environment and healthy economy can coexist when it approved oil and gas leasing reforms to restore balance to public lands management. We need to stay the course and ensure that oil, gas, wind and solar energy are produced responsibly and the hunting, fishing and recreation that sustain local communities across the country can continue." Ed Arnett, director of the Theodore Roosevelt Conservation Partnership’s Center for Responsible Energy Development "As the new Congress gets down to work, hunters and anglers remain committed to finding common-ground solutions for responsibly managing the natural resources that are so important to the economy and our way of life. Legislation that would maintain sportsmen’s access to public lands, fully fund conservation programs and enact a framework for more efficient, responsible public land renewable energy development are potential bipartisan accomplishments." Corey Fisher, energy team lead for Trout Unlimited Take the Clean Earth Challenge and help make the planet a happier, healthier place.Learn More Promoting more-inclusive outdoor experiences for allRead More A groundbreaking bipartisan bill aims to address the looming wildlife crisis before it's too late, while creating sorely needed jobs.Read More More than one-third of U.S. fish and wildlife species are at risk of extinction in the coming decades. We're on the ground in seven regions across the country, collaborating with 52 state and territory affiliates to reverse the crisis and ensure wildlife thrive.
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A diverse coalition of prominent pastors and Christian faith leaders including Bishop T.D. Jakes, Harry Jackson, Samuel Rodriguez and niece of Dr. Martin Luther King Jr., Alveda King, are expected to meet at a summit in Dallas, Texas, on Thursday to discuss ways to promote practical steps toward racial reconciliation in America. At the summit, according to a release from the organizers, the faith leaders are expected to focus on seven "Bridges to Peace" community initiatives namely: reconciliation and prayer forums; education policy reform; community engagement forums; community service and compassion outreaches; personal, marriage and family development; engagement with the criminal justice system; and economic development strategies. Organizers of the event, which is being hosted by Jackson, chairman of High Impact Leadership Coalition and senior pastor of Hope Christian Church, are also requesting that President Barack Obama specifically address educational reforms, urban economic development policies, and criminal justice reforms that have the potential to alleviate the racial divide during his Jan. 20 State of the Union address. "It was Dr. King who said that injustice anywhere is a threat to justice everywhere," Jakes, senior pastor of The Potter's House megachurch, noted in the statement. "We cannot continue as if we live in a post-racial society, when there is mounting evidence to the contrary. Recent history is loudly telegraphing the need for a meaningful dialogue on race," he added. That loud telegraph calling for meaningful dialogue of race came in the form of the controversial deaths of Staten Island, New York, father Eric Garner, and 18-year-old Michael Brown, who was shot and killed in Ferguson, Missouri, during a physical confrontation with a police officer last year summer. The incidents have sparked protests from hundreds of thousands of Americans across the country calling for racial justice and other needed reforms. Other leaders who are expected to be in attendance include: Tony Perkins, president of the Family Research Council; Jerry Boykin, executive vice president of the Family Research Council; Tony Evans, senior pastor of Oak Cliff Bible Fellowship and founder and president of The Urban Alternative; James Robison, founder and president of LIFE Outreach International and co-host of LIFE Today TV; R.A. Vernon, founder and senior pastor of The Word Church; and Jim Garlow, senior pastor at Skyline Church.
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According to a press release March 28, registered military voters can use a newly-developed Blockchain platform for mobile voting in the Primary Elections from March 23 until polling day May 8. The platform is limited to voters in two counties and is a joint venture between the Office of the Secretary of State of West Virginia, technical provider Voatz, Tusk/Montgomery Philanthropies, New America and the Blockchain Trust Accelerator platform. “This pilot project is the first of its kind in the United States. The mobile voting application uses blockchain technology to provide a secure voting process,” the release confirms. “...To improve accessibility and enhance confidence in our electoral system, West Virginia Secretary of State Mac Warner authorized his Elections Division staff to pursue a mobile voting pilot for the 2018 Primary Election.” The US has until now made less headway in secure Blockchain voting than countries such as Estonia, with the partnership conspicuously drawing comparisons to jurisdictions ‘ahead of the game’ in securing ballot casting and other operations. “Government institutions around the world, including Brazil, Estonia, Denmark, South Korea, and Switzerland are actively pursuing the integration of blockchain technology,” they note. Eligible voters require only “a compatible Apple or Android mobile device and approved, validated State or Federal ID” to use the Blockchain service.
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The planet changes every day. Maybe completely unnoticed, but it happens under the influence of various factors: from natural to anthropogenic. The latter is especially important because today we are creating a noosphere that already extends beyond the Earth. However, no matter how much we dream of space, we still need to take care of our planet, and Google has shown a video that captures the changes in the planet over the past 37 years. Changes on Earth It is important to understand that there were many reasons for the planet not to remain stable. Global warming today triggers mechanisms that cannot always be tackled. Very often we give in to the brute force of nature, as we are not physically able to cope with this task. However, as practice shows, the man himself with his construction plans to create not a new society, but new buildings, cities, farms have the greatest impact on the planet. No wonder the Earth has changed so much in some forty years. And Google was able to capture that with satellite imagery. The company has put together 24 million frames in an interactive interface and has made an exciting video that immerses us in the relatively recent past. What happened in 37 years Some places have remained virtually unchanged. For example, the Mamoru River in Bolivia does not seem to be feeling the effects of global warming at all. During all this time, it remained unchanged. The city of Chatham in Massachusetts has also undergone little change. In any case, they do not look so significant against others. By the way, about them. Many of us have heard the “success story” of the United Arab Emirates, including the city of Dubai. In some 37 years, it has turned from a small, barely visible town into a huge one with a large infrastructure and even buildings on the sea. What is it, if not the desire of man to extend his influence even further, and to the sea? Greenland’s peninsula – the Land of Mulius-Eriksen – is the best evidence that changes in nature are still taking place, and global warming is gradually but erasing the snow from the face of our planet. Scientists have also presented a video where similar processes occur with our ocean.
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The Xeon Phi co-processor is based upon a new technology developed by Intel Corporation to provide greater compute performance through massive parallelism and designed to fit many high-performance computing applications. The first Xeon Phi-based HPC system, Stampede, will be deployed in early 2013 at the Texas Advanced Computing Center as part of the National Science Foundation’s Extreme Science and Engineering Discovery Environment (XSEDE) program. In conjunction with a larger project, David Hudak, Ph.D., program director for cyberinfrastructure and software development at the Ohio Supercomputer Center (OSC), recently led a research team that examined the performance of different HPC algorithms on pre-release Xeon Phi hardware. The group included OSC staff members John Eisenlohr, Ph.D., a systems developer and engineer, and Karen Tomko, Ph.D., a senior researcher in computer science. Kurt O’Hearn, an undergraduate student at Grand Valley State University, worked with the team as part of an XSEDE student engagement project. “The unique design of the Xeon Phi architecture required the specification of application parallelism for maximum performance,”Hudak explained. “It is important for application developers to experiment and gain experience on the best way to structure applications to exploit the Xeon Phi.” To achieve this end, Hudak’s group performed a detailed performance analysis of a well-known communication-avoiding QR factorization algorithm (CAQR), compared CAQR performance between the first- and second-generation Xeon Phi chips and restructured the algorithm for improved performance. “QR factorization is a linear algebra routine fundamental to solving commonplace problems in the sciences and engineering,” said Hudak. “As such, it has been extensively studied on all major HPC architectures: vector, MPP, SMP, cluster, multi-core cluster and GPU cluster.” The parallelization of the CAQR algorithm proved non-trivial due to load imbalance caused by the decreasing amount of matrix to be factored as the algorithm progresses. To better understand the behavior of the algorithm on the Xeon Phi, timing methods were used to measure the total execution time and the four main kernels. The team concluded that CAQR execution time on the XeonPhi is sensitive to both matrix shape and tile shape and that the optimal tile shape appears to correlate with cache size (larger tiles perform better with larger caches). They also found that the execution time for two kernels dominates for larger thread counts, indicating a need for improved collective operations. Project lead: David Hudak, Ohio Supercomputer Center Research title: Parallel application development for the Intel Xeon Phi platform Funding source: Intel, Ohio Supercomputer Center Web site: http://bit.ly/OSC-RR-Hudak
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Crypto-currencies and ICO are, certainly, the VIPs of the world of modern technologies. Having gathered a record $4 billion investments last year, they continue taking the fancy of both professional investors and beginners in the field. Still, according to many experts and analysts, the pace of this crypto-currency fever is gradually declining due to the fact that about a half of all blockchain projects do not reach their goal. Disclosure: This is a Sponsored Article Until recently, entering the ICO was completely possible for projects without a clear development plan or the ones collecting money for just “some idea”, with no connection to a real product. Now, such approach only indicates the immaturity of a project and is a warning signal for potential investors. It is quite a natural twist: the mistakes made have helped the participants of the crypto-currency process to become smarter and more demanding, the agiotage has subsided. A working technology and a prototype ready to be scaled should be at the heart of a promising and safe investment project. Only teams from the real economy sector can meet these requirements and the rapidly changing trends of the crypto-industry. Such teams will open the access to high-tech industries to their investors via the ICO. Yet in this case there are own pitfalls, too. The examples of real production ICO are two projects that succeed in attracting investments for the development: one for a sand quarry openworks, another one for organizing the production of zirconium. In both cases, the product is real (sand and zirconium) but it is not unique and cannot be tokenized. Consequently, these projects have collected their share of investments, but have not shown any results so far. Becoming a high-yield asset by to combining a new patented material, already operating production and blockchain is possible for a European project, Nafen. The pre-sale on it starts on March 22 and will continue for 2 months. Several years ago, the project team has patented the technology of the production of Nafen aluminum oxide nanofibers, which can improve their structure of various materials when added to it. The production of these nanofibers has started in the European Union, in Estonia. At the moment, the Nafen team cooperates with many large chemical companies in Europe and the USA. The project has repeatedly won in the programs for innovation industry development in the European Union and has received a number of grants from the European Commission. The demand for European nanofibers explains the plans to expand the production of it. To meet the needs of the Asian and European markets, the team plans to build a new high-tech factory. To do this, it intends to collect 14 million euros with the help of smart contracts and token called NFN based on Ethereum blockchain. “The high-tech production of Nafen nanofibers is a project that has already passed the stage of a “promising startup”. Now it is a really working business with an experienced team interested in exerting themselves, with a road map, an own industrial site and serious customers. In our case we are talking about a project that is going to disrupt tremendous profits over the next two years.” commented the project’s CEO, Roman Gertcev. He emphasizes that Nafen can be tokenized, because the nanofibers are a unique patented material that can not be faked or reproduced by some other technology. The exclusivity of the nanofibers and the working production site make the project a promising participant of the blockchain process. Nafen nanofibers are thin nanoscaled fibers with a diameter of only 10-20 nanometers and a length of up to 15 centimeters. Such fibers are not found in nature and can only be created by an artificial method. They are produced by controlled synthesis of Al2O3 aluminium oxide nanostructures on the surface of aluminum melt in the presence of special oxidizers. Being a unique nanomaterial, Nafen is already used to solve many urgent problems. For instance, in the creation of light and strong composite polymer materials for cars and yachts frames and hulls; durable and safe lithium-polymer batteries; various catalyst systems; high-strength concrete compositions, geopolymer composites. Nafen can also be used to create materials of increased durability suitable for extreme conditions — the space and the Arctic. The patented technology for the production of nanofibers can be easily scaled depending on the volume of demand for the material. This makes Nafen extremely available for application in a wide variety of fields of science and production, compared to other commercial nanomaterials.
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Obesity is a global problem. According to World Health Organization (WHO) figures, more than 1.9 billion adults were overweight, 650 million of them obese, in 2016. A study by Imperial College London and WHO revealed a tenfold increase in childhood and adolescent obesity in four decades. Many public health programs have been launched, and all have failed miserably. The problem is just getting worse. Contributing factors are the constant availability of high-energy foods and high levels of physical inactivity. So far, no effective medication has been developed. Could the psilocybin in magic mushrooms bring a halt to the obesity epidemic? The people at Vancouver-based psychedelic bioscience company NeonMind think it’s a possibility. The company is on a mission to leverage the psilocybin in magic mushrooms canada to curb obesity. The chemical compound has already shown that it can treat PTSD and treatment-resistant depression by changing thinking and behavior patterns. The company has conducted a preclinical trial on rats that indicated positive effects of psilocybin in reducing weight gain. The rat models had unlimited amounts of Nutella to eat for seven days. Then they were divided into two groups, one receiving either a microdose of psilocybin or a macrodose and a control group that didn’t get any psilocybin. The rats that received the drug put on less weight as a result of their Nutella habit compared to those that didn’t receive the psychedelic. The company’s website states that the psilocybin reduced weight gain by 31% in those that received the low dose and 28% for the high dose receivers. Collaboration with scientists at the University of British Columbia NeonMind is collaborating with scientists from the University of British Columbia to design a study that will examine whether the drug could help people to lose weight and maintain their weight loss. NeonMind has engaged Dr. C. Laird Birmingham, a psychiatry professor at the University of British Columbia and an expert in eating disorders, to help with its Phase 2 clinical trials. He has widespread experience designing clinical trials to investigate treatments for a range of eating disorders, and has been appointed to NeonMind’s Board of Advisors. In a press release, Dr. Birmingham says, ‘’The tricky with the treatment of stoutness is primarily that of weight upkeep. Most people lose weight, but they infrequently maintain. Psilocybin has the likely to serve as a fresh and different tool to assistance people misplace weight and preserve their weight loss by changing neural pathways. Improved habits and cognitions can growth caloric expenditure connected to non-exercise and exercise energy expenditure and reset the behaviors and cognitions that link life stress and trauma to eating behavior.’’ NeonMind is busy with a preclinical trial at the University of British Columbia investigating psilocybin’s potential to help people lose weight. The company is also developing a Phase 2 Human Clinical Trial, slated to start in 2022. The potential of Magic Mushrooms Canada to treat disorders that have traditionally been resistant to treatment lies in its ability to change how people think and behave. Both microdosing and macrodosing seem to have this effect. Obesity causes many diseases and health problems and the WHO has formally recognized it as a global epidemic. Eating disorders, in general, have been one of those intractable health conditions that have resisted effective treatment. Excessive weight is the cause behind many serious health problems that could be alleviated if scientists can understand how magic mushrooms works and can succeed in translating that knowledge into effective psilocybin-based medications.
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Mardi Gras occurs once a year on Tuesday, either in February or March and is celebrated for over a week. On the French Catholic holiday, Leesville’s French Club celebrated the green, the purple and the gold. What is Mardi Gras, though? According to Merriam-Webster, Mardi Gras is “a carnival period climaxing on Shrove Tuesday.” However, those who have been submerged in the culture know that it is more than a carnival. Mostly celebrated in Louisiana, people gather together for this last day of feasting before giving up certain food and pleasers for Lent. During the celebration, balls and parties are held along with parades. The French club showed a video of the Krewe of Rex’s parade, the main parade company in New Orleans. Different parade companies have been scattered throughout Louisiana for centuries. Leesville’s homecoming parade is a modest version of the major parades in Louisiana. The motor floats are yards high and wide covered in elaborate decorations. Those on the floats are dressed in large gowns and tuxedos with masquerade masks and hats. They throw out beads, cups, medallions, coins and stuffed animals to the crowd standing nearby as the floats pass. The crowd is contrived of families and friends of all ages, including the really young and elderly. Before the float, many people spend the day at the sight playing games and eating. Every float and every experience is different. Sometimes, it will be freezing and raining or humid and hot. Some people snatch the thrown items from others while some are very considerate. After the video, the officers cut the King Cake, which is served at all Mardi Gras parties. Resembling a large donut, the King Cake is filled with custard and has sprinkles on the top in the official Mardi Gras colors. Traditionally, green represents faith, purple justice and gold power. As to traditions, the host of the party enters a tiny plastic baby that represents Jesus into the cake from underneath. Originally, a golden bean was inserted into the cake instead. Whichever party guest finds the baby in their slice is expected to host the next Mardi Gras party. The passing of the King Cake is also practiced in many Louisiana Sunday schools. After the cake, French club decorated face masks with markers, crayons and feathers. Masks can be found on those involved in the parade, at one or at a party. In centuries past, the hosts would throw extravagant masquerade balls rather than modern day parties. Even though Mardi Gras has slightly changed over the years, and is mainly celebrated in Louisiana, being involved in the holiday is addicting. For many, attending only one Mardi Gras parade or party will never be sufficient.
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Phenylalanine was the minimalistic and first of numerous nonproteinaceous building blocks to be demonstrated to form amyloid-like fibrils. This unexpected organization of such a simple building block into canonical architecture, which was previously observed only with proteins and peptides, has numerous implications for medicine and supramolecular chemistry. However, the morphology of phenylalanine fibrils and their mechanical properties was never characterized in solutions. Here, using electron and atomic force microscopy, we analyze the morphological and mechanical properties of phenylalanine fibrils in both air and fluids. The fibrils demonstrate an exceptionally high Young's modulus (up to 30 GPa) and are found to be composed of intertwined protofilaments in a helical or twisted ribbon morphology. In addition, X-ray scattering experiments provide convincing evidence of an amyloidal cross-β-like secondary structure within the nanoassemblies. Furthermore, increasing the phenylalanine concentration results in the formation of highly homogenous, noncrystalline, self-healing hydrogels that display storage and loss moduli significantly higher than similar noncovalently cross-linked biomolecular nanofibrillar scaffolds. These remarkably stiff nanofibrillar hydrogels can be harnessed for various technological and biomedical applications, such as self-healing, printable, structural, load-bearing 3D scaffolds. The properties of this simple but quite remarkable hydrogel open a possibility to utilize it in the biomaterial industry. - quantitative nanomechanical atomic force microscopy
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It is surprising that not more has been written about Claudia Jones given her stunning achievements as an activist, freedom fighter ideologist and theoretician. The fact that she is buried next to Karl Marx is an appropriate but not an adequate epitaph. The bare bones of her all too short life — she died at the age of 49 — is relatively well known. She was born in 1915 in Trinidad and emigrated with her parents, an aunt and three sisters to the US where they settled in Harlem; and where she and her family, like most of the black population, experienced appalling racism and great poverty. These experiences, together with the trumped-up case against the Scottsboro ‘boys’ (1935-6), led Claudia, aged 18, to join the Young Communist League (YCL). This is how she put it: ‘It was out of my Jim Crow experiences as a young negro woman, experiences likewise born of working-class poverty that led me to join the Young Communist League and to choose the philosophy of my life, the science of Marxism-Leninism — that philosophy not only rejects racist ideas, but is the antithesis of them’. This quote indicates that very early on in her life she understood the relationship between exploitation and oppression and in particular the connection between class, race and gender. This was something that informed her politics throughout her life both in the US and later when she was deported to England. Although she rose swiftly through the ranks of the YCL and the party this did not stop her retaining a critical view of what she perceived as a gender-blind and colour-blind approach to women’s and negro oppression (she always used the term ‘negro’ as it was in common parlance at the time). She was supported on the issue of oppression, however, by William Z Foster, who served as general secretary of the CPUSA from 1945-57 after the expulsion of the former general secretary Earl Browder. In the bitter struggle against Browderism, Jones supported the party’s rejection of the ‘revisionist position on the national character of the negro question’. In a long discussion article entitled On the Right to Self-Determination for the Negro People in the Black Belt, she argued that the CPUSA had always understood that the negro question was a special question taking on the character of a national question. She made a distinction between the position of negros in the north and in the Black Belt where they constituted a majority of the population. She argued that self-determination was not the same as separation and argued that the former had to be seen as a ‘programmatic demand’ and a ‘guiding principle’. She quoted Lenin, who argued that the negro people in the US constituted an ‘oppressed nation’. She was informed by his teachings which is why she opposed Browder from1944. The latter by now envisaged a rosy future for ‘peaceful capitalism’ which would end racism, imperialism and exploitation. Jones was imprisoned for writing and delivering an International Women’s Day address in which she strongly supported the fight for peace against imperialist aggression. Furthermore she castigated the left and the party for failing to uproot male supremacist ideas. Such ideas ensured that the stated aim of building a mass party was unlikely to be achieved given that women constitute half the population and that while working-class women are doubly oppressed, black women are triply oppressed. Further, echoing Clara Zetkin, she criticised bourgeois feminism, which instead of seeing women’s oppression as founded on class exploitation, viewed it as stemming solely from men, substituting ‘the battle of the sexes’ for the class struggle. Jones quotes Engels, citing his work on The Origin of the Family, Private Property and the State, in which he said that within the family the man is the bourgeois and the woman the proletarian. Thus: ‘Marxist-Leninists fight to free women from household drudgery, they fight to win equality for women in all spheres, they recognise that one cannot adequately deal with the woman question or win women for progressive participation unless one takes up the special problems, needs and aspirations of women as women’ (from We seek Full Equality for Women, 1949). In the same article she wrote that the CPUSA was the first party to demonstrate to white women and to the working class ‘that the triply oppressed status of negro women is a barometer of the status of all women’. After several periods of imprisonment under the viciously anti-communist Smith and McCarran Acts, she was eventually deported. She suffered bouts of serious ill health as a result of her prison experiences, in particular, a heart problem which was untreated. Because she was not a US citizen she was eventually deported to England because Trinidad was still a British colony. In Britain she continued her activism. She founded the West Indian Gazette and the Notting Hill Carnival and remained a communist until her dying day. This article originally appeared in the Morning Star.
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- Concept shares same powertrain as experimental hydrogen-powered Corolla Sport, currently racing in Super Taikyu race series in Japan - Powered by modified GR Yaris engine to use hydrogen as fuel - Hydrogen combustion engine technology delivers almost zero emissions while retaining the acoustic and sensory sensations typical for combustion engines - Development continues through harsh conditions of motorsport in Japan Toyota showcased its experimental hydrogen-powered combustion engine technology in the multiple award-winning GR Yaris. The hydrogen fuel, fuel tanks and refuelling process of the experimental vehicle are the same as found in the Mirai, Toyota’s commercially available flagship fuel cell electric vehicle. However, whilst the Mirai employs chemical reaction in the fuel cells to generate energy, the experimental GR Yaris features an internal combustion engine with hydrogen as the fuel. While the hydrogen combustion engine technology is still in the early stages of conceptual development and experimentation, which started in 2017 and not yet ready for commercialisation, Toyota’s experimental hydrogen-powered Corolla Sport is already delivering high performance at motorsport events in Japan with almost zero tailpipe emissions.“ Japan’s auto industry must succeed in building passenger vehicles. To this end, manufacturers must participate in auto-racing to test their vehicles’ durability and performance and display their utmost performance. With competition comes progress, as well as excitement among motoring fans. The aim of racing is not just to satisfy our curiosity, but rather to enable the development of the Japanese passenger vehicle industry.Kiichiro Toyoda, Founder of Toyota Motor Corporation (March, 1952) The hydrogen-powered experimental GR Yaris and the Corolla Sport both feature the same G16E-GTS, 1.6-litre, in-line 3-cylinder, turbocharged engine that is found in the award-winning GR Yaris, but with a modified fuel supply and injection system for use with hydrogen as fuel. The experimental hydrogen-powered Corolla Sport has already been competing in the Super Taikyu race series in Japan since May this year under the ROOKIE Racing arm of Toyota GAZOO Racing where the team has taken on the challenge to test the experimental hydrogen combustion engine under the harsh environments of motorsport.“ We’ve taken the first step to compete with and develop our hydrogen-powered engine with the mindset of taking on the challenge. I imagine things will look a little different 10 years from now, and I hope people will look back and see how we took on the challenge with positivity and enjoyed every moment of it.Akio Toyoda, President of Toyota Motor Corporation Hydrogen combusts at a faster rate than petrol, resulting in good responsiveness whilst delivering excellent environmental performance. In addition to being extremely clean, hydrogen combustion has the added potential to relay a fun to drive experience with the acoustic and sensory sensations that characterise internal combustion engines. Towards achieving carbon neutrality, Toyota has been strengthening its efforts, such as by aiming to promote the use of hydrogen through the popularisation of FCEVs and numerous other fuel-cell-powered products. By further refining its hydrogen-engine technologies through motorsports, Toyota intends to aim for the realisation of an even better hydrogen-based society. Source: Toyota, https://newsroom.toyota.eu/toyota-showcases-experimental-hydrogen-powered-gr-yaris/
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Your browser does not support the audio element. Exodus 10:7-11 Then Pharaoh’s servants said to him, “How long shall this man be a snare to us? Let the men go, that they may serve the LORD their God. Do you not yet understand that Egypt is ruined?” So Moses and Aaron were brought back to Pharaoh. And he said to them, “Go, serve the LORD your God. But which ones are to go?” Moses said, “We will go with our young and our old. We will go with our sons and daughters and with our flocks and herds, for we must hold a feast to the LORD.” But he said to them, “The LORD be with you, if ever I let you and your little ones go! Look, you have some evil purpose in mind. No! Go, the men among you, and serve the LORD, for that is what you are asking.” And they were driven out from Pharaoh’s presence. 1 Corinthians 10.1-4 For I do not want you to be unaware, brothers, that our fathers were all under the cloud, and all passed through the sea, and all were baptized into Moses in the cloud and in the sea, and all ate the same spiritual food, and all drank the same spiritual drink. For they drank from the spiritual Rock that followed them, and the Rock was Christ. 1 Corinthians 12.12-26 For just as the body is one and has many members, and all the members of the body, though many, are one body, so it is with Christ. For in one Spirit we were all baptized into one body—Jews or Greeks, slaves or free—and all were made to drink of one Spirit. For the body does not consist of one member but of many. If the foot should say, “Because I am not a hand, I do not belong to the body,” that would not make it any less a part of the body. And if the ear should say, “Because I am not an eye, I do not belong to the body,” that would not make it any less a part of the body. If the whole body were an eye, where would be the sense of hearing? If the whole body were an ear, where would be the sense of smell? But as it is, God arranged the members in the body, each one of them, as he chose. If all were a single member, where would the body be? As it is, there are many parts, yet one body. The eye cannot say to the hand, “I have no need of you,” nor again the head to the feet, “I have no need of you.” On the contrary, the parts of the body that seem to be weaker are indispensable, and on those parts of the body that we think less honorable we bestow the greater honor, and our unpresentable parts are treated with greater modesty, which our more presentable parts do not require. But God has so composed the body, giving greater honor to the part that lacked it, that there may be no division in the body, but that the members may have the same care for one another. If one member suffers, all suffer together; if one member is honored, all rejoice together. Please subscribe to my podcast in iTunes or another player.
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Assistant professor phytochemicals at the Laboratory of Food Chemistry http://www.fch.wur.nl / http://www.linkedin.com/company/fchwur Phytochemicals are small molecules produced by plants’ secondary metabolism. These compounds have a wide diversity of functionalities in the plant, including defence against biological threats. Many of them are known to be reactive molecules in food and they often possess beneficial bioactive properties. In my work, we study the phytochemicals present in food-related plants and plant-derived food ingredients. To this end, we employ advanced chemical analytical techniques, such as ultra-high performance liquid chromatography coupled to high resolution mass spectrometry (UHPLC-HRMS). One of our goals is to identify plant defence compounds that may possess antimicrobial activity against food spoilage or pathogenic microorganisms. We study the production, analysis, and modification of these defence compounds as leads for novel antimicrobials. Among the classes of phytochemicals we study, phenolic compounds are the most well-known. Two important subclasses of phenolic compounds are (iso)flavonoids and stilbenoids, which are produced in many plants, including legumes (e.g. soy bean, peanuts). A modification known as prenylation, which occurs naturally in these plants as part of their defence against biological threats, enhances the bioactivity of (iso)flavonoids and stilbenoids. Therefore, prenylated (iso)flavonoids and stilbenoids are known to be highly bioactive. In particular, they can possess potent antimicrobial properties. This has led to much interest in these compounds from the perspectives of both academic research and industry. We develop methods for analysis of prenylated (iso)flavonoids and stilbenoids and for their production via biological, enzymatic, and chemical approaches. Moreover, phenolic compounds, especially those possessing catechol-moieties, can participate in oxidative reactions and interactions with metals. Additionally, these molecules can be metabolised by gut microbiota, while at the same time also affecting the gut microbiota composition. In this part of my work, we study the molecular mechanisms underlying structural modifications, interactions, and reactions of phenolic compounds.
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|Title||The X-ray weakness of GPS radio galaxies:a volume-limited complete sample| |Author||Dr Matteo Guainazzi| |Description||We propose to observe a flux- and volume-limited complete sample of GPS radio galaxies. The goal of the proposals is to determine: a. the presence of hot confining gas around the active nucleus, and its properties, through its optically thin soft X-ray emission; b. the presence of cold environment gas through the measurement of X-ray absorption - in the most extreme case, Compton-thick. These measurements will provide tests for the current scenarios to explain the origin of these objects. We request 4 targets to be observed within the XMM-Newton AO2, for a total allocation time of 80 ks. This list includes 1404+286, the first GPS radio galaxy where a poor quality ASCA observation suggests the above components may have been simultaneously detected.| |Publication||No observations found associated with the current proposal| |Instrument||EMOS1, EMOS2, EPN, OM, RGS1, RGS2| |Mission Description||The European Space Agency's (ESA) X-ray Multi-Mirror Mission (XMM-Newton) was launched by an Ariane 504 on December 10th 1999. XMM-Newton is ESA's second cornerstone of the Horizon 2000 Science Programme. It carries 3 high throughput X-ray telescopes with an unprecedented effective area, and an optical monitor, the first flown on a X-ray observatory. The large collecting area and ability to make long uninterrupted exposures provide highly sensitive observations. Since Earth's atmosphere blocks out all X-rays, only a telescope in space can detect and study celestial X-ray sources. The XMM-Newton mission is helping scientists to solve a number of cosmic mysteries, ranging from the enigmatic black holes to the origins of the Universe itself. Observing time on XMM-Newton is being made available to the scientific community, applying for observational periods on a competitive basis. |Publisher And Registrant||European Space Agency| |Credit Guidelines||European Space Agency, 2004-02-28T00:00:00Z, 014096, 17.56_20190403_1200. https://doi.org/10.5270/esa-co1vvwz|
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Found helpful. Broccoli is a highly antioxidant green vegetable with NRF2-dependent characteristics. Leave a comment Name. Close cart. Eat 4 to 6 small meals a day. Walnuts are a vegetarian source of kung fatty acids. Researchers found that the supplements reduced obstructions in the airway and for be jealth complementary treatment for asthma health. Thank you for sharing such information. Meeting with a registered dietitian nutritionist RDN will help you get on track. Fish high in fat is an excellent choice of food for healthy lung as they contain high levels of diet fatty acids which are linked with lung health. Found useful Reply. Broccoli is said to have an active constituent called L-sulforaphane, which tricks the cells to switch on the anti-inflammatory genes that further avoids respiratory conditions. I found this article helpful in choosing health foods for my diet, and dlet, Lung learned about the POWERbreathe plus, which I believe, will improve the strength of my lungs. To gain weight: Eat a variety of whole-grain carbohydrates and fresh fruits and vegetables. If you suffer oxygen deprivation then it can be serious to your health leading to lung respiratory illnesses and diet including for, COPD and diet. Your RDN or health det suggest you drink a liquid called a medical for product supplement.
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By Euro Weekly News Media • 08 December 2013 • 17:13 FIFTY-FIVE per cent of the population of the Balearic Islands claims to feel as Spanish as they do Balearic. Data revealed from a survey carried out by Gadeso shows that the feeling of duality continues to exist amongst the population and remains the same as when the last survey was carried out in February. However, the while the number of people who feel more Balearic than Spanish has risen to 20 per cent, those who feel more Spanish than Balearic have fallen to 12 per cent. Causes for this, the survey shows, may be perception of a degree of ‘abuse’ from the central government, especially when it comes to the amount of money assigned to the area. On the other hand, it could be partly due to the “continuous attacks against the local language from the president of the Balearic Government, Jose Ramon Bauza.” Results are similar on the four islands and also amongst different age groups. Fewer than 1 per cent of the population in the Balearic Islands identifies with the Catalans, and most say they feel that they belong to their own island. Share this story Subscribe to our Euro Weekly News alerts to get the latest stories into your inbox! By signing up, you will create a Euro Weekly News account if you don’t already have one. Review our Share your story with us by emailing [email protected], by calling +34 951 38 61 61 or by messaging our Facebook page www.facebook.com/EuroWeeklyNews Your email address will not be published. Required fields are marked * Download our media pack in either English or Spanish.
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New QAS Tests These are real, previously administered SAT tests on the current 1600-point scale by the College Board. QAS stands for “Question Answer Service” and basically allows test takers to review their scores with a given copy of the test and answers. It is only available for select exam dates each year, which is why they are so limited but also very helpful as they directly reflect what your test will be like. Note: Some of the QAS tests are official SAT practice tests, so they have not been included here.
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SurgiSTUD offers an alternative to cadavers for surgical training. We manufacture customizable 3D printed surgical training and utility device models with high biomechanically fidelity that offers real life haptic feel AND significant cost savings over cadaveric options. Our models are completely customizable. We use patient specific CT scans to replicate anatomy/pathology or existing deformities. Our models are very inexpensive when compared to a cadaver as there are no associated lab expenses, transportation charges, any of the additional fees (such as disposable, delivery, environmental, infectious disease tests, etc.). Our models also have an extended shelf life over cadaveric options. We are available worldwide and have patents globally. Our models eliminate some cultural concerns that cadavers have in some countries. Our models are perfect for deliberate, simulated training. Most of our models can be used multiple times or for multiple procedures. Surgeons have the opportunity to simulate a complex case and practice before performing on the actual patient. All of our bones have been biomechanically tested, so they have the same fidelity and haptic feel of real bones. We are getting a lot of really fantastic feedback. The most common response that we get is, “Finally – a solution to a void in the industry!” There is currently a shortage in cadaver availability, sources are stating that they are at about 40% capacity. It is super exciting time for us to be able to offer an alternative platform. The neurosurgeon inventor, Dr. Michael Bohl, had a need for additional hands- The initial concept was to develop the models specifically for surgeons, but we continue to find more markets that could benefit from using our models. Right now, I think the biggest market that we impact is the medical device companies. Medical device companies turn to SurgiSTUD when looking for a platform for effectively demonstrating the quality of their medical devices, when seeking to reduce costs of organizing training courses, when looking for alternatives to cadavers for patient specific or custom pathologies and anatomies, or for increasing sales through surgeon demonstration, education, and outreach, also and when they are frustrated by the lack of reliable benchtop testing for product development to develop and test navigation systems and implant systems.
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For two decades Light Detection and Ranging (LiDAR) data has been used to develop spatially-explicit forest inventories. Data derived from LiDAR depict three-dimensional forest canopy structure and are useful for predicting forest attributes such as biomass, stem density, and species. Such enhanced forest inventories (EFIs) are useful for carbon accounting, forest management, and wildlife habitat characterization by allowing practitioners to target specific areas without extensive field work. Here in New England, LiDAR data covers nearly the entire geographical extent of the region. However, until now the region’s forest attributes have not been mapped. Developing regional inventories has traditionally been problematic because most regions – including New England – are comprised of a patchwork of datasets acquired with various specifications. These variations in specifications prohibit developing a single set of predictive models for a region. The purpose of this work is to develop a new set of modeling techniques, allowing for EFIs consisting of disparate LiDAR datasets. Artificial Intelligence (AI) algorithms were developed to interpret LiDAR data and make forest predictions. After settling on the optimal algorithm, we incorporated satellite spectral, disturbance, and climate data. Our results indicated that this approach dramatically outperformed traditional modeling techniques. We then applied the AI model to the region’s LiDAR, developing 10 m resolution wall-to-wall forest inventory maps of fourteen forest attributes. We assessed error using U.S. federal inventory data and determined that our EFIs did not differ significantly in 33, 25, and 30/38 counties when predicting biomass, percent conifer, and stem density.
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Top Canadian arts and cultural organizations are cautioning patrons that some of their personal data may have been exposed in a recent security incident involving their e-mail service provider. WordFly, which a sends e-mails on behalf of clients including the National Ballet of Canada, Toronto Sympathy Orchestra (TSO), Canadian Opera Company (COC), Canadian Stage and The Musical Stage Company, was hit by a ransomware attack on July 10 , according to a statement by the marketing service’s business development director, Kirk Bentley. Mr. Bentley wrote that the incident rendered WordFly’s technology inaccessible and that the “bad actor” exported the e-mail addresses that the company’s customers use to reach subscribers. He also said that as of July 15, the data was deleted by the attacker, and that at this time, the information is not believed to be sensitive in nature. Cyber threats are on the rise and becoming more sophisticated, Canadian Center for Cyber Security spokesperson Evan Koronewski said in an e-mail to The Globe. Although cybercriminals can target organizations of any size, they are “particularly skilled” at targeting those with large databases for higher paydays. According to the 2022 TELUS Canadian Ransomware Study83 per cent of Canadian businesses reported attempted ransomware attacks, while 67 per cent have fallen victim to one. In light of July’s incident, the National Ballet of Canada said in an e-mailed statement to The Globe and Mail that it’s working closely with other arts organizations “to create an unified response.” A statement by the TSO recommended that patrons stay hopeful of phishing e-mails, texts or calls that ask for personal information or have links and attachments. They also suggested the use of stronger passwords. “You want to protect personal information because it can be used for not good purposes, it can be used to launch a cyberattack,” Canadian Cyber Threat Exchange strategic adviser Bob Gordon said in an interview with The Globe. “[If] I know that you do something with the Symphony and now I have your e-mail address, I can now send you an e-mail tailored to look like it’s coming from the Toronto Symphony … to try to convince you to do something that ultimately will assist me in launching an attack against you.” An e-mail from the COC informed patrons that their names, e-mails and COC IDs might have been compromised while assuring that no financial information was leaked. “We have been assured that the incident has been contained,” said a similar e-mail by Canadian Stage, a performance arts company based in Toronto. Cybercriminals use ransomware to prevent users from accessing their systems or files through data encryption or removal. A ransom is then demanded to regain access and get information back, Mr. Gordon explained. “One thing that happens with ransomware is that data doesn’t have to have any value to the attacker, it just has to be of value to the victim,” he said. The victim needs that information to keep operating matters such as supplier lists, customer lists and invoices. Other notable clients whose data were handled by Wordfly and are potentially compromised include The Smithsonian Institution in the US and the Sydney Dance Company in Australia. British arts organizations such as Southbank Centre, Royal Shakespeare Company, Royal Opera House, The Old Vic and the Courtauld Institute of Art were also among the victims. The TSO, the COC and the National Ballet of Canada indicated that they have temporarily partnered with Mailchimp, another e-mail provider, until WordFly restores services. The TSO, the COC and WordFly did not respond to requests for comment.
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Is the pandemic finally behind us, or should we still expect the worst? Crisis exit scenarios seem to be emerging, but the Covid-19 is not beaten. The arrival of new, more contagious and more virulent variants could again tip the health situation. The International Science Council has also recently published a report on the future of the pandemic, which Numerama echoes. The scientists behind this study, specializing in public health or virology, have drawn up three plausible paths until 2027: a pessimistic forecast, a mixed one and an optimistic one. Here they are in detail. “Missed Recovery”, is the most pessimistic forecast. According to scientists, political tensions could be right for the proper management of the health crisis. They thus imagine that those refractory to political ideologies could refuse anti-Covid vaccination. Less than 60% of the world’s population would then be effectively vaccinated against the virus during the next 5 years. At the same time, new variants would continue to appear. The circulation of the Covid-19 would then be very dense. According to the WHO, “striving to vaccinate 70% of the population of each country remains essential to control the pandemic, with priority given to health workers, the elderly and other groups at risk”. According to Maria Van Kerkhove, epidemiologist within the organization, at present “the virus still has a lot of energy”. What is the second track they predict? The second track, more subdued, was named “Continuity”. Here, the authors of the report do not envisage any improvement or deterioration in the global management of the health crisis. They rely on the delay. In the situation where low-income countries have the lowest vaccination rates, in the event of an epidemic rebound, restrictive measures could be taken. The virus would then become endemic and vaccines would have to be regularly updated in order to effectively combat the different variants. What about the best scenario? The best scenario is named “Collaboration Plus”. Here, the Covid-19 would weaken in particular thanks to the high vaccination coverage of the population. According to scientists, more than 70% of people worldwide will have received at least one dose of an effective vaccine by 2027. This would allow high protection against Covid on an international scale. Potential confinements and other restrictions can then be avoided. For this, the monitoring of epidemiological data is necessary, estimates the WHO.
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All this talk about Story, all this talk about reading the Bible’s narrative, all this talk … well, what difference does it make? More precisely, what difference does it make for the Christian life? I ape Paul’s words: “much, in every way.” But that only means we have to explain how it makes a difference. What words are the preeminent words in your faith community that summarize the Christian life? Daniel Kirk, in Jesus Have I Loved, But Paul?, sketches how Jesus’ kingdom vision and Paul’s theology are harmonious and it leads him to a study how we are to live in light of this narrative approach to Paul. The essential shape of that story is that Israel’s Story has been fulfilled in the Story of Jesus, his life, death, burial and resurrection. So what then does this mean? Again, Daniel shows how Jesus’ theory of the Christian life and Paul’s theory of the Christian life are so much alike. Kirk focuses on Mark’s Gospel where we find that Jesus’ essential call is to follow Jesus (Mark 1:16-20), and this means we are to extend the ministry of Jesus. And here he draws on Mark 3:13-15 and 6:7-13 to show that we extend his very life and ministry, but this leads to the big one: the pattern of Jesus’ life in Mark is the life of rejection, suffering, death and resurrection. The Christian life then is to be noted by the cross — a life of sacrificial love for others (Jesus Creed and John 13). The heart of Mark’s narrative is the Messiah pointing toward and then dying on the cross. Christology shapes discipleship; thus, christology shapes ecclesiology. Jesus’ pattern is our pattern. This is the essence, too, of Paul’s theory of the Christian life. We are to be and live “in Christ,” and the Christ we are “in” is the one who suffered and died and was raised. That is, Phil 2:6-11 tells it all: be like Jesus and Jesus was like this: humiliation, suffering, death, resurrection. The way to the top is the bottom. So the Christian life is the embodiment of the life of Christ. This death-life is followed by the resurrection-life: God’s Spirit, the agent of new creation, is at work in those who die, in those who in baptism are buried in death with Jesus Christ and who are raised with him. They are glowing clay pots (2 Cor 4:7-10). This story, the life of suffering leading to resurrected life, is not the pattern of our society or our churches (enough). Too often the narrative of success: prosper, enterprise, large churches, best-selling books, etc are what attracts us. Instead of a list of death instances we only want the list of successes. This leads Kirk to friendly fire for his Reformed justification-by-faith-alone society. (Only James has that expression by the way, as Kirk reminds us.) Too often it diminishes obedience and thrives on passive acceptance, and not enough of the “obedience of faith” taught by Paul in Romans 1:6. He contends there’s a tendency here to “produce an underdeveloped sense of Christian responsibility” (90). Faith works, he says. “To be justified by faith is never to be justified by faith that stands alone” (92).
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LewVac Kapton® insulated in-vacuum wiring is designed for high and ultrahigh vacuum environments and is bakeable to 250°C. All conductors and braided coaxial shields are constructed with silver plated copper wire. (Except cryogenic & thermocouple pair). Insulation is a high mechanical strength Kapton® type F film that is applied and heat treated to minimise trapped gasses. Multiconductor cables are available in either flat ribbon or circular configuration with an outer PEEK (polyetheretherketone) monofilament weave. Circular cable conductors are colour coded for ease of wiring. For non coded wires LewVac offers coloured glass identification beads in six easy to distinguish colours, see associated products for details. • UHV compatible construction. • High temperature rated to 250°C. • Kapton® type F insulating film. • Silver plated copper conductors. • Single, multi-strand and coaxial wires. • Ribbon cables. • Type K thermocouple wire. Voltage : 3kVAC – 10kVDC Current : See tables Material Conductor : Silver plated copper Insulation : Kapton® type F film Kapton® Properties Dielectric constant : 2.9 Dielectric strength : 80kV/mm Dissipation factor,1MHz : 0.002 Initial tear : 13.4kg/mm Moisture absorbtion : 0.4% @ 50% RH Temperature Range : -75°C to 250°C
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Green tea extracts are rich in anti-oxidants and, therefore may delay skin ageing and prevent wrinkles. The soap also has some anti bacterial properties and is said to soothe skin irritations and help in prevention of acne. The tea leaves in the soap help exfoliate and cleanse the skin, and the olive oil extracts leave it feeling fresh and moisturised. Olive Oil soaps were one of the first vegetable made soaps. They are hand made using traditional cold process making method. Soaps made with vegetable oils have many beneficial properties for skin. They are also SLS and parabens free. The natural fat provides protection, improves skin tone, softness and youth of skin through restructuring oil action. Each soap has special properties relating to essential oils and other natural ingredients in them.
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Precepted by Shawn Gaffney. The Hieroglyphics series will present students with a basic understanding of Egyptian hieroglyphs, grammar, and knowledge about how to proceed with further study. In this sequence of courses we will discuss how to translate steles that you are likely to encounter in museums, as well as their cultural significance. As student progress, the class will tackle more complex translation. Each one-month module builds on the previous one, so students ready to learn Hieroglyphics will communicate with our Director and Professor Gaffney to make the right placement for everyone. See the overall page for the Egyptian Hieroglyphs 2 module. See other modules (potentially) offerred in April 2022. See other modules in the Language sector. Days and Times Meeting Tuesdays & Thursdays @8:00 PM Eastern Daylight Time
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Ramesh Raskar is a Massachusetts Institute of Technology Associate Professor and head of the MIT Media Lab's Camera Culture research group. Previously he worked as a Senior Research Scientist at Mitsubishi Electric Research Laboratories (MERL) during 2002 to 2008. He holds 132 patents in computer vision, computational health, sensors and imaging. He received the $500K Lemelson–MIT Prize in 2016. The prize money will be used for launching REDX.io, a group platform for co-innovation in Artificial Intelligence. He is well known for inventing MIT NETRA (mobile device to calculate eyeglasses prescription), EyeCatra (cataract screening) and EyeSelfie (retinal imaging), Femto-photography (trillion frames per second imaging) and his TED talk for cameras to see around corners. In February 2020, Raskar and his team launched Private Kit: SafePaths, a public health tool for contact tracing for COVID-19 pandemic. He is also the Founder and Chief Scientist of PathCheck. He is a co-founder of Akasha.im which was acquired by Alphabet spin-off company Intrinsic. Early life and education Ramesh Raskar was born in Nashik and he finished his engineering education from College of Engineering, Pune. He finished his PhD at UNC Chapel Hill. Mitsubishi Electric Research Laboratories Raskar joined Mitsubishi Electric Research Laboratories in 2002. His significant contribution in computer vision and imaging domain led him to win 'TR 100' in 2004, 'The Global Indus Technovator Award' in 2004 respectively. MIT Media Lab Raskar joined MIT Media Lab in 2008. Raskar, together with others developed a computational display technology that allows observers with and some other eye disorders to perceive a focused image on a screen without wearing refraction-corrective spectacles. The technology uses a light field display in combination with customized filtering algorithms that pre-distort the presented content for the observer. His lab produced a number of extreme highspeed pictures using a femto-camera that took images at around one-trillion frames per second. They have also developed a camera to see around corners using bursts of laser light. Juliett Fiss has covered his role as the catalyst behind the Siggraph NEXT program at Siggraph 2015 in Los Angeles. Raskar was awarded the "2017 CG Achievement Award" by ACM SIGGRAPH for his potential contribution in computational photography and light transport and their applications for social impact. He has been influential in deploying research ideas in the real world. Startups created by members of his CameraCulture research group include EyeNetra.com (ophthalmic tests), Photoneo (high speed 3D sensing), Labby (AI for food testing), Lumii (novel printing for 3D imagery), LensBricks (computer vision with computational imaging), Tesseract (personalized display) and more. Non-profits emerging from his efforts include REDX.io (AI for Social Impact), MIT Emerging Worlds, LVP-MITra, REDX-WeSchool, DigitalImpactSquare and more. He serves on the Expert Commission of $3.5 Billion Fondation Botnar as AI and Health expert. Philosophies on Innovation Raskar has presented a series of talks and workshops on innovation processes. They include his Idea Hexagon, How to give an engaging talk, How to prepare for a thesis, How to write a paper and the Spot-Probe method for problem-solution identification. In 2019, he presented doctoral hooding commencement speech at UNC Chapel Hill. Key ideas from his interview with Lemelson Foundation are as follows. Cleverness alone is not enough to become a good inventor Inventor's job is to think in an anti-disciplinary manner – look beyond disciplines The true power of an inventor is less about expertise on one subject, but rather the ability to ask questions no one else is asking and follow the trail of answers as they are revealed. The "spot probe" methodology is something every inventor needs to master. It is a continual cycle: Ask a lot of questions. Spot a lot of problems. Articulate those problems. Then probe their potential solutions. Solving big societal problems requires both passion and skill, but those qualities exist on two different axes. The hardest problems to work on are found where those two axes intersect – where passion meets skill. To make a grand difference, ensure the problem you're trying to solve is the right problem. Solve the right problems at the right time. Invention is all about people. If you don't work with the right people you don't get inspired to work in the right way. Difference between problem-solving and invention – working in isolation can just solve a problem, while to invent you need give and take. See the world in a new or different way, and great things will happen. The next generation of young inventors will then spot a whole new set of problems and probe for solutions that no one can begin to predict. Philosophy of DAPS/DOPS and its global impact In his recent talk, Raskar mentioned, "Instead of apps, let’s think about DAPS (Digital Applications for Physical Services) Or DOPS. If you want to make it broader, we can have DOPS (Digital Opportunities for Physical Services). With DOPS and DAPS we have an opportunity to impact the physical world in areas where we simply couldn’t before". Raskar's philosophy on 'Learn, Think and Apply' encourages him to form REDX.io platform. REDX's goal is to promote peer to peer learning, peer to peer problem solving in more systematic ways! REDX labs are working on following keywords: Wearables, Agriculture, Camera, Health, Unorganized Sector, Satellite Imaging, Machine Learning, Mobile, Social Graph, Crowd Sourcing, Sensors. They are physical lab with very well-funded and innovators working with critical problems. REDX Mumbai is funded by TATA trust. DISQ in Nashik funded by TCS foundations, a multibillion-dollar lab. REDX lab in Brazil is well funded by local trust. REDX clubs operate as non-profit organizations. Innovators and their solutions have the opportunity to interact with other REDX clubs and work in REDX labs worldwide. The onboarding process to become a REDX club includes a 10-week course, appointing a board and an academic advisor, establishing a community coalition, and recruiting innovators and mentors. Clubs receive certification directly from Dr.Raskar. Awards and Fellowships TR100 Award from Technology Review (recognizes top young innovators under the age of 35) The Global Indus Technovator Award (instituted at MIT to recognize the top 20 Indian technology innovators worldwide) MIT Sloan Research Fellowship DARPA Young Faculty Award LAUNCH Health Innovation Award, presented by NASA, USAID, US State Dept and NIKE Vodafone Wireless Innovation Project Award (first place) Lemelson–MIT Prize ($500,000) 2017 ACM SIGGRAPH Achievement Award 2019 Jack Dangermond Award $10,000 for GeoSpatial Research in a Journal Paper (for Street Address for All)
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Food & Drink – Grow & Eat Your Own Produce Food & Drink: Before we set off we cleared the shelves of all of the boxes of Decaf Ty-phoo from our local pound land, at £1 for 80 bags this is a bargain only 1.25 pence per bag. We are using a Bodum teapot which gives us 4 cups of tea from one tea-bag, that’s 0.3p per cup!! The teapot can also be used to hold tea leaves. There are many leaves which can be used from the garden e.g Melissa officinalis (Lemon Balm) is pretty prolific and can even be foraged for, as can fresh mint to make tea or Pimms! Our favourite is the soothing Aloysia citrodora (Lemon verbena/ lucia lima), amazing to be able to grow your own tea. These leaves are also available from the local Portuguese markets, a bag costing only €1. Five leaves per pot should do, cheap as chips, very natural and so many health benefits, much better than caffeinated tea from the supermarket! During November the olives are ready to pick. A net was placed on the grass to catch any falling olives whilst a ladder is used to prune the tree. Once a branch is cut down the olives can be easily picked off and dropped onto the net. The thicker branches can then be trimmed and used for firewood and the leaves pilled up and fed to the goats. When the tree is pruned the net of olives can be scooped up into buckets, the buckets poured into large sacks. By combining with the neighbour, we totalled nine sacks at thirty kilos per sack, there are several olive press’ available to take the olives to. The press will take their cut of the oil, which still left fifty litres of the good stuff. Read our post here about harvesting our own olives in Spain. Mmmm the smell of freshly baked bread. If you want bread in under an hour from scratch, without yeast (as you don’t always have this in your cupboards) try this Soda Bread Recipe: Preheat the oven to 400F/200C/Gas 6. Into a large mixing bowl stir together 170g/6oz self-raising wholemeal flour, 170g/6oz plain flour,½ tsp salt and ½ tsp bicarbonate of soda. Make a well in the centre and pour in 290ml/½ pint buttermilk, mixing quickly with a large fork to form a soft dough. Add more milk or flour as the dough should not be too sticky or wet. (The buttermilk is acidic so it reacts with the bicarb acting as a leavening agent). Turn onto a lightly floured surface and knead briefly. Shape into a round and flatten the dough slightly before placing on a lightly floured baking sheet. Cut a cross on the top and bake for about 30 minutes or until the loaf sounds hollow when tapped. Leave your lovely loaf to cool. During November the forest is full of a small red/orange round bumpy fruit known as the Madrono berry (Irish strawberry?) It grows on the Arbutus tree. It tastes a bit gritty when eaten straight from the tree, but it makes a really delicious jam or jelly. Whilst the dogs were off exploring the woods we would pick a tub full. To make; Madrono Berry Jam: Rinse fruits. Put them in a pan and cover with cold water almost completely. Heat and cook for over low heat, the berries will lose their shape and become mushy. Pass the mushy fruit through a cheesecloth or fine net, squeeze well to catch any juice. Weigh the juice, (I sometimes had 500- 1000g). Mix the juice with its equal weight of sugar. ((I tried using less sugar, which was still delicious but trickier to cook)). Simmer over low heat, skimming any foam which forms on the top at times. Check the consistency, cooking is complete when the hot juice is thick enough to form small beads. Let it cool down before placing in sterilised jars. Enjoy on toast the next morning! I’ve always liked marmalade, those shreds of peel suspended in a luxurious orange jelly. The Seville orange is completely bitter, much too tart to eat from the tree or juice, but it’s perfect to use for marmalade, the peel is so tantalising tangy. I followed the bbcgoodfood.com seville orange marmalade recipe with good results. The two jars on the left of the picture were Seville orange marmalade. The fruit in the bowl and on the chopping board are Kumquats. We had three small trees in the garden which produced hundreds of these little citrus. These make a really delicious marmalade once you have sliced them all and removed the pips! (see pic below) Freshly squeezed juice. The oranges were on the trees, ready to pick from November through to April. The large nobly Seville oranges were out of the question, too bitter, the naval oranges on the other hand were so good, depending on their size I would pick and squeeze up to twenty each morning for a jug full of fresh juice, nothing added. The grapefruits were available from a small tree in the front garden in December and Jan, an acquired taste, but I love it. My mum was over on her surprise birthday visit, she loved the tart juice too. Another fruit ready in November, perfect around christmas time is the pomegranate. There were two large trees, spiky trees! full of pomegranates. Ranging in size, some of the fruits were bursting open on the tree, revealing their ruby-red jewel like seeds. Pomegranate seeds freeze really well, we kept a couple of large bags full of frozen seeds, great to add to smoothies, salads or to blend and sieve for juice. Pomegranate Juice: Simply slice in half, hold in one hand and hit them on the back to remove the seeds over a bowl, some of the seeds will burst but the juice will land in the bowl. (Maybe do this outside, ha ha) Pick out any pith which may have landed in the bowl. Place the seeds and juice from the bowl into a blender, once blended pour through a fine net/ sieve/ muslin for pure, super healthy pomegranate juice or dilute with water to taste.
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Since we’re all housebound and Amazon is still delivering, it’s a perfect time to shop online for some fresh arts and crafts activities. All kids light up at a new creative project, but especially our right brain kids. They need to create. They need to make stuff. Helping your child tap into their creative side doesn’t have to break the bank. Kids of all ages love to get art supplies as gifts. But don’t feel like you have to spend the big bucks to give your kids hours of creative fun. Here are 14 gift ideas, most of which you can find at your local arts and crafts store. Many families turn to extra curricular activities to provide what their kids need more of. After school enrichment programs can give these learners the things they’re missing out on during regular school hours. But how do you choose the right one for your child?
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Flight time from London to Phnom Penh is 14 hours 5 minutes. Can you fly direct from London to Cambodia? How to get to Cambodia. There are no direct flights to Cambodia from Europe, North America, Australasia or South Africa, so if you plan to fly into the country you’ll need to get a connecting flight from elsewhere in Southeast or East Asia. How far away is Cambodia on a plane? How long is the flight to Cambodia? An average nonstop flight from the United States to Cambodia takes 32h 59m, covering a distance of 8636 miles. How long is flight to Siem Reap? The average flight time to Siem Reap is 13 hours and 25 minutes. How many hours is Cambodia from UK? The total flight duration from London, United Kingdom to Phnom Penh, Cambodia is 12 hours, 58 minutes. Is Cambodia open for tourists now? After results show they are free of Covid-19, they are allowed to travel across Cambodia.” Also, Siem Reap, which is the gateway tot he ruins of the beautiful Angkor Wat temple complex is also going to reopen sooner than January. How far is it from Cambodia to UK? The distance between Cambodia and United Kingdom is 6192 miles. How long is the flight to Thailand from UK? For flights from the UK to Thailand, the most common direct route is from London to Bangkok which takes around 12 hours 15 minutes and lands at Suvarnabhumi Airport. How long is a flight to Vietnam from UK? The total flight duration from London to Hanoi is 11 hours and 5 minutes and from London to Ho Chi Minh is 15 hours and 5 minutes including a stopover. Which airports fly to Siem Reap? Siem Reap Airlines |Cambodia Angkor Air||K6||www.cambodiaangkorair.com| |China Eastern Airlines||MU||en.ceair.com| Is the airport in Siem Reap open? The airport is fully open and has deployed health safety measures for its stakeholders. How long is flight from Bangkok to Siem Reap? 0h 50min is the average flight time from Bangkok to Siem Reap. Where is Cambodia situated? Cambodia is situated in southeast Asia on the coast of the Gulf of Thailand and has a total area of 181 040 km2 (Table 1). It is bordered by Thailand in the west, Lao People’s Democratic Republic in the north and Viet Nam in the east.
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Erik Kennedy – Learn UI Design Free Download. Cheap… Confidently design beautiful user interfaces for any app or site. I’m going to paint a little picture. You can tell if me if this is you or not. You want to learn UI design, but you feel it’s confusing and open-ended. You find the advice out there vague, contradictory, and not really practical. When you look at design topics like typography, color, or process, you’re thinking: crap, I can’t do this! And what makes for beautiful design seems like some mix of: - Easy to recognize, but difficult to create I’m all too familiar with these feelings. When I was a developer and PM, I felt this way constantly. I saw all these awesome-looking designs, and could even tell you which ones I liked the best, but when it came to recreating something similar for myself, I was hopeless. I saw UI designers as magical creatures who sprinkle mysterious design dust over any wireframe and make it shine. It seemed like some art school voodoo that was completely inaccessible to others – myself included. But enough was enough. I decided to learn UI design. WHY UI DESIGN? Everyone’s reasons for learning user interface design are different. If you’re already a developer, a PM, a UX designer, etc., why develop this totally separate skill? Let’s break it down: - UX Designers. You can present designs as beautiful mockups that your coworkers will rally around. You can work with interfaces from concept to pixel-perfection. Your portfolio stands light-years ahead of your peers. - Developers. You can cover for design on your team. You can spiff up your side-project’s interface, instead of finding/hiring a designer. You can translate designs to code with minimal hassle, because you understand the aesthetic underpinnings. - PMs. You can create amazing mockups for pitching new features and flows. You can work alongside your designers, and provide spot-on feedback for excellent product. - Entrepreneurs. Like it or not, a good presentation for your ideas matters. Your marketing site, your app – even your pitch deck. Eventually, you’ll be in the big leagues and can hire out – but even then, a solid foundation in design will help you communicate and lead. - Print Designers. More and more design work shifts to digital every day. You’ve got to learn the ropes, figure out this whole “responsive” business, and practically re-build your portfolio to keep working in the field you love. For me, I had left my job to become a freelance UX designer, and my portfolio looked about as good as a Pentagon Powerpoint. Not to mention every one of my clients was asking: “hey, now that you made these wireframes, can you do the actual designs?” It was clear I could offer more to my clients if my end product wasn’t sketched out boxes and arrows. So how do you learn UI design in 2020? Sales Page: https://learnui.design/
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Pin, Shaft, Spindle The important components of most of products. Metal pin is a component used for terminal contact, fastening objects together, inserted in a slot, groove or hole. A spindle is a rotating axis of the machine, which often has a shaft at its heart. A shaft is a rotating machine element, usually circular is cross section, which is used to transmit motion from one part to another. Those products are normally made of brass, stainless steel or carbon steel.
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