query stringlengths 16 395 | positive sequencelengths 2 2 | negative sequencelengths 98 98 | cluster int64 0 1.02k |
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Is the 5-HT(1Dbeta) receptor gene implicated in the pathogenesis of obsessive-compulsive disorder? | [
"Obsessive-compulsive disorder (OCD) is a psychiatric condition for which strong evidence of a genetic component and serotonergic system involvement exists. Recent studies have shown that sumatriptan, a selective ligand of the serotonin (5-HT)(1Dbeta) autoreceptor, modifies OCD symptoms. The aim of this study was t... | [
"Autism spectrum disorders (ASD) often show obsessive repetitive symptoms that are characteristic to obsessive-compulsive disorder (OCD). Aberrant glutamate function has been suggested to a risk for both ASDs and OCD. Considering the common metabolic pathway and recent results from association studies both in OCD a... | 0 |
Are premonitory urges a prerequisite of tic inhibition in Gilles de la Tourette syndrome? | [
"Despite the common notion that premonitory urges facilitate tic inhibition, no studies have investigated this question systematically. We examined the relation of the trait of premonitory urges with tics and tic suppression. We hypothesised that patients with more urges would be more efficient at inhibiting tics. ... | [
"To assess whether cortico-cortical inhibition (CCI) induced by paired-pulse transcranial magnetic stimulation (TMS) is influenced by 'preferential' or 'non-preferential' activation of the motor cortex. Paired-pulse TMS (conditioning-test paradigm with interstimulus intervals of 2-5 ms) with a round coil centered o... | 0 |
Does deep brain stimulation induce striatal dopamine release in obsessive-compulsive disorder? | ["Obsessive-compulsive disorder is a chronic psychiatric disorder related to dysfunctional dopaminer(...TRUNCATED) | ["Whereas apathy is known as a common consequence of subthalamic nucleus deep brain stimulation in P(...TRUNCATED) | 0 |
"Does behavior therapy augment response of patients with obsessive-compulsive disorder responding to(...TRUNCATED) | ["In many patients with obsessive-compulsive disorder (OCD), residual symptoms persist despite a cli(...TRUNCATED) | ["yes. Cognitive-behavioral therapy can alleviate psychological symptoms in elderly patients with an(...TRUNCATED) | 0 |
"Are stressful life events at onset of obsessive-compulsive disorder associated with a distinct clin(...TRUNCATED) | ["Environmental stressors are considered to play an important role in the triggering of mental disor(...TRUNCATED) | ["Traumatic exposure may modulate the expression of impulsive behavioral dispositions and change the(...TRUNCATED) | 0 |
"Are obsessive-compulsive tendencies and undermined confidence related to reliance on proxies for in(...TRUNCATED) | ["We have previously hypothesized that obsessive-compulsive (OC) tendencies are associated with a ge(...TRUNCATED) | ["yes. The present data suggest that high anxiety predisposes rats to lose control over cocaine-but (...TRUNCATED) | 0 |
Impulsivity in anxiety disorder patients: is it related to comorbid cyclothymia? | ["The relationship between anxiety and impulsivity is controversial and not well explored. In a prev(...TRUNCATED) | ["The inferior frontal cortical (IFC)-striatal network plays an integral role in response inhibition(...TRUNCATED) | 0 |
Does genome-wide linkage analysis of obsessive-compulsive disorder implicate chromosome 1p36? | ["Obsessive-compulsive disorder (OCD) has a complex etiology involving both genetic and environmenta(...TRUNCATED) | ["yes. The genetic regions 3q26-27 and 2q34-37 might contain susceptibility genes for CHD. Linkage t(...TRUNCATED) | 0 |
"Are obsessive compulsive symptoms associated with better functioning independently of cognition in (...TRUNCATED) | ["Although the relationship of obsessive-compulsive symptoms (OCSs) with both cognition and social f(...TRUNCATED) | ["Psychosis is hypothesized to occur on a spectrum between psychotic disorders and healthy individua(...TRUNCATED) | 0 |
"B lymphocyte antigen D8/17: a peripheral marker for childhood-onset obsessive-compulsive disorder a(...TRUNCATED) | ["It has been hypothesized that Sydenham's chorea, a major manifestation of rheumatic fever, may pro(...TRUNCATED) | ["To evaluate associations between attention-deficit/hyperactivity disorder (ADHD) and comorbid psyc(...TRUNCATED) | 0 |
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