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Is human immunodeficiency virus the major determinant of steatosis and hepatitis C virus of insulin resistance in virus-associated fatty liver disease? | Whereas HIV confers a higher risk of steatosis, VAFLD is associated with higher IR than NAFLD and such an effect is specifically linked to HCV rather than to HIV infection. | 100 |
Do tumor necrosis factor-alpha and its inducer inhibit morphine-induced rewarding effects and sensitization? | These results suggest that TNF-alpha inhibits MOR-induced rewarding effect and sensitization by regulating extracellular dopamine levels, and Leu-Ile inhibits them via the induction of TNF-alpha. | 101 |
Does multifactor dimensionality reduction reveal a three-locus epistatic interaction associated with susceptibility to pulmonary tuberculosis? | We have identified statistically significant evidence for a three-way epistatic interaction that is associated with susceptibility to TB. This interaction is stronger than any previously described one-way or two-way associations. This study highlights the importance of using machine learning methods that are designed t... | 102 |
Does the ATM inhibitor KU55933 sensitize radioresistant bladder cancer cells with DAB2IP gene defect? | Loss of DAB2IP expression in BCa cells signifies their radioresistance. KU55933, which suppresses ATM phosphorylation upon irradiation, could be applied in the radiotherapy of BCa patients with a DAB2IP gene defect. | 103 |
Is 7q11.23 duplication syndrome inherited ? | 7q11.23 duplication syndrome is considered to be an autosomal dominant condition, which means one copy of chromosome 7 with the duplication in each cell is sufficient to cause the disorder. Most cases result from a duplication that occurs during the formation of reproductive cells (eggs and sperm) or in early fetal dev... | 104 |
Is osteoarthritis associated with symptoms of common mental disorders among former elite athletes? | OA might be a risk factor for developing symptoms of CMD in former elite athletes. The clinical relevance of this study is that an interdisciplinary approach to the clinical care and support of former elite athletes after their careers is advocated as the interaction between the physical and mental health issues occurr... | 105 |
How many people are affected by GM3 synthase deficiency ? | GM3 synthase deficiency appears to be a rare condition. About 50 cases have been reported, mostly from Old Order Amish communities. | 106 |
What are the treatments for Childhood Craniopharyngioma ? | Key Points
- There are different types of treatment for children with craniopharyngioma. - Children with craniopharyngioma should have their treatment planned by a team of health care providers who are experts in treating brain tumors in children. - Childhood brain tumors may cause signs or s... | 107 |
How many people are affected by harlequin ichthyosis ? | Harlequin ichthyosis is very rare; its exact incidence is unknown. | 108 |
What causes Erdheim-Chester disease ? | The specific underlying cause of Erdheim-Chester disease is not known. It is not currently categorized as a cancer, infection or autoimmune disease. It it not believed to be contagious or genetic in nature. | 109 |
Do topical corticosteroids reverse the antiviral effect of topical cidofovir in the Ad5-inoculated New Zealand rabbit ocular model? | These experimental data further support the clinical development of cidofovoir as a topical antiviral agent, but they do not support a treatment regimen that includes a combination of topical corticosteroids and topical cidofovir as a desirable strategy for the treatment of symptomatic adenoviral ocular infection. | 110 |
How many people are affected by Costeff syndrome ? | Costeff syndrome affects an estimated 1 in 10,000 individuals in the Iraqi Jewish population, in which at least 40 cases have been described. Outside this population, only a few affected individuals have been identified. | 111 |
Does maternal plasma from pregnant women with umbilical placental vascular disease affect endothelial cell mRNA expression of nitric oxide synthase? | Maternal plasma from pregnancies with umbilical placental vascular disease did not affect endothelial cell expression of nitric oxide synthase. This finding does not support a maternal origin for the factor demonstrated in fetal plasma. These results suggest separate pathogenic pathways for the endothelial cell activat... | 112 |
How many people are affected by Kleefstra syndrome ? | The prevalence of Kleefstra syndrome is unknown. Only recently has testing become available to distinguish it from other disorders with similar features. | 113 |
How many people are affected by dihydropyrimidinase deficiency ? | Dihydropyrimidinase deficiency is thought to be a rare disorder. Only a few dozen affected individuals have been described in the medical literature. | 114 |
Does association of serologic status for Neospora caninum and postweaning feed efficiency in beef steer? | Significant reductions in short-term weight gain and feed efficiency were associated with the presence of antibodies against N. caninum in postweaning beef steers. | 115 |
Is youth screen-time behaviour associated with cardiovascular risk in young adulthood : the European Youth Heart Study? | Prolonged TV viewing and total screen time during leisure time in adolescence, and increases in these behaviours, are associated with unfavourable levels of several cardiovascular risk factors in young adulthood. | 116 |
What are the treatments for Osteoporosis ? | A comprehensive osteoporosis treatment program includes a focus on proper nutrition, exercise, and safety issues to prevent falls that may result in fractures. In addition, your doctor may prescribe a medication to slow or stop bone loss, increase bone density, and reduce fracture risk. Nutrition. The foods we eat con... | 117 |
What are the treatments for Parasites - Leishmaniasis ? | Before considering treatment, the first step is to make sure the diagnosis is correct.
Treatment decisions should be individualized. Health care providers may consult CDC staff about the relative merits of various approaches. Examples of factors to consider include the form of leishmaniasis, the Leishmania species... | 118 |
Is desmoid tumor inherited ? | Most desmoid tumors are sporadic and are not inherited. Sporadic tumors result from gene mutations that occur during a person's lifetime, called somatic mutations. A somatic mutation in one copy of the gene is sufficient to cause the disorder. Somatic mutations in either the CTNNB1 or the APC gene can cause sporadic de... | 119 |
Does cross-platform gene expression signature of human spermatogenic failure reveal inflammatory-like response? | A gene expression signature of human spermatogenic failure was revealed which comprised well-studied examples of inflammation-related genes also increased in other pathologies, including autoimmune diseases. | 120 |
How many people are affected by ataxia with oculomotor apraxia ? | Ataxia with oculomotor apraxia is a rare condition. Type 1 is a common form of ataxia in Portugal and Japan. Type 2 is estimated to occur in 1 in 900,000 individuals worldwide. | 121 |
What are the treatments for Phacomatosis pigmentovascularis ? | If phacomatosis pigmentovascularis (PPV) is not associated with systemic complications (e.g., Sturge-Weber syndrome, Klippel-Trenaunay syndrome, eye conditions) it requires no treatment, however pulsed dye laser may improve the appearance of port wine stains and Q-switched laser the appearance of pigmentary nevus. Medi... | 122 |
Do oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway? | Our data indicate that the oxidative species ONOO(-) and H(2) O(2) increase arginase activity/expression through PKC-mediated activation of RhoA/Rho kinase pathway. | 123 |
Is multiple mitochondrial dysfunctions syndrome inherited ? | This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. | 124 |
Is balloon dilation with adequate duration safer than sphincterotomy for extracting bile duct stones : a systematic review and meta-analyses? | Duration of EPBD is inversely associated with pancreatitis risk. Currently recommended ≤1-minute dilation actually increases pancreatitis. EPBD with adequate duration may be preferred over EST because of comparable pancreatitis but lower overall complication rates. | 125 |
Do immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion? | Arginine enhanced expression of the early proinflammatory transcription factor AP-1 but not NF-kappaB. This represents a novel mechanism by which arginine may be harmful when administered to critically ill patients. | 126 |
How many people are affected by multiple epiphyseal dysplasia ? | The incidence of dominant multiple epiphyseal dysplasia is estimated to be at least 1 in 10,000 newborns. The incidence of recessive multiple epiphyseal dysplasia is unknown. Both forms of this disorder may actually be more common because some people with mild symptoms are never diagnosed. | 127 |
What are the treatments for Lupus ? | For information on the treatment of lupus, you can read the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) publication called Handout on Health: Systemic Lupus Erythematosus. NIAMS is the primary NIH organization for research and information on lupus. | 128 |
Does prolonged exposure to acid and bile induce chromosome abnormalities that precede malignant transformation of benign Barrett 's epithelium? | Prolonged acid and bile exposure induced chromosomal aberrations and clonal selection in benign BAR-T cells. Since aneuploidy preceded morphological/dysplastic changes in the BEC model, chromosomal aberrations may be an early predictor of BE progression. The [t(10;16) and dup(11q)] aberrations identified in this study ... | 129 |
What is (are) Glucocorticoid-remediable aldosteronism ? | Glucocorticoid-remediable aldosteronism is one of three types of familial hyperaldosteronism and was first described in 1966. Aldosterone is a hormone manufactured by the adrenal glands which helps the body retain water and sodium and excrete potassium. It is caused by a fusion of the CYP11B1 and CYP11B2 genes and is i... | 130 |
What are the treatments for Ehlers-Danlos syndrome ? | There is no specific cure for Ehlers-Danlos syndrome (EDS). The treatment and management is focused on preventing serious complications and relieving associated signs and symptoms. Because the features of EDS vary by subtype, management strategies differ slightly. For more specific information on the treatment of each ... | 131 |
What causes Congenital hepatic fibrosis ? | Isolated congenital hepatic fibrosis is rare. Congenital hepatic fibrosis is usually associated with conditions known as hepatorenal fibrocystic diseases (FCD) that can also affect the kidneys. Examples of FCDs include polycystic kidney disease (PKD) and nephronophthisis (NPHP). FCDs can be inherited as autosomal reces... | 132 |
What is the outlook for Childhood Central Nervous System Germ Cell Tumors ? | Certain factors affect prognosis (chance of recovery). The prognosis (chance of recovery) depends on the following: - The type of germ cell tumor. - The type and level of any tumor markers. - Where the tumor is in the brain or in the spinal cord. - Whether the cancer has spread within the brain and s... | 133 |
Does the brain renin-angiotensin system play a crucial role in regulating body weight in diet-induced obesity in rats? | The brain renin-angiotensin system affects body weight regulation, feeding behaviour and metabolic disorders. When angiotensin II levels are low in brain, rats are protected from developing diet-induced obesity and obesity-related metabolic impairments. We further suggest that telmisartan at least partly lowers body we... | 134 |
What is (are) Female Infertility ? | Infertility means not being able to get pregnant after at least one year of trying (or 6 months if the woman is over age 35). If a woman keeps having miscarriages, it is also called infertility. Female infertility can result from age, physical problems, hormone problems, and lifestyle or environmental factors. Most ... | 135 |
How many people are affected by GLUT1 deficiency syndrome ? | GLUT1 deficiency syndrome is a rare disorder. Approximately 500 cases have been reported worldwide since the disorder was first identified in 1991. In Australia, the prevalence of the disorder has been estimated at 1 in 90,000 people. However, researchers suggest that the disorder may be underdiagnosed, because many ne... | 136 |
Do different neurophysiologic patterns of myoclonus characterize Lennox-Gastaut syndrome and myoclonic astatic epilepsy? | These neurophysiologic findings indicate that epileptic myoclonus in LGS originates from a stable generator in the frontal cortex, to spread to contralateral and ipsilateral cortical areas, whereas myoclonus in MAE appears to be a primary generalized epileptic phenomenon. | 137 |
Are activated lymphocytes and high liver expression of IFN-γ associated with fulminant hepatic failure in patients? | These findings indicate the involvement of NK and NKT cells as well as T lymphocytes CD4(+) and CD8(+) in the inflammatory process inducing FHF, confirmed by the high hepatic expression of IFN-γ. | 138 |
Is hereditary sensory and autonomic neuropathy type IE inherited ? | This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In most cases, an affected person has one parent with the condition. | 139 |
Are diet-induced obesity and insulin resistance associated with brown fat degeneration in SIRT1-deficient mice? | Diet-induced obesity and insulin resistance are associated with BAT degeneration in SIRT1-deficient mice, which further underlined the beneficial role of SIRT1 in obesity-associated metabolic disorders. | 140 |
What is (are) Generalized pustular psoriasis ? | Generalized pustular psoriasis is a severe inflammatory skin condition that can be life-threatening. Affected people develop episodes of red and tender skin with widespread pustules throughout their body. This is generally accompanied by fever, chills, headache, rapid pulse rate, loss of appetite, nausea and muscle wea... | 141 |
Does fearful imagery induce hyperventilation and dyspnea in medically unexplained dyspnea? | Fearful imagery provokes hyperventilation and induces subjective symptoms of dyspnea and palpitation in patients with medically unexplained dyspnea. | 142 |
What is (are) fragile X-associated primary ovarian insufficiency ? | Fragile X-associated primary ovarian insufficiency (FXPOI) is a condition that affects women and is characterized by reduced function of the ovaries. The ovaries are the female reproductive organs in which egg cells are produced. As a form of primary ovarian insufficiency, FXPOI can cause irregular menstrual cycles, ea... | 143 |
What are the symptoms of Neutropenia chronic familial ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Neutropenia chronic familial. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medi... | 144 |
Do airway epithelial cells from asthmatic children differentially express proremodeling factors? | AECs from asthmatic children differentially express TGF-β2, VEGF, and periostin compared with cells from atopic nonasthmatic and healthy children. Nasal epithelial cells might be a suitable surrogate for bronchial cells that could facilitate investigation of the airway epithelium in future longitudinal pediatric studie... | 145 |
How many people are affected by Perry syndrome ? | Perry syndrome is very rare; about 50 affected individuals have been reported worldwide. | 146 |
Does interleukin-22 suppress the growth of A498 renal cell carcinoma cells via regulation of STAT1 pathway? | IL-22 dose-dependently suppresses RCC cell line A498 cells in vitro and induces growth inhibition of A498 cell-bearing mouse xenografts. These results suggest that the anti-RCC effects of IL-22 are at least partially mediated through regulation of STAT1 signaling pathways and G2/M cell cycle arrest, rather than by indu... | 147 |
How many people are affected by lung cancer ? | In the United States, it is estimated that more than 221,000 people develop lung cancer each year. An estimated 72 to 80 percent of lung cancer cases occur in tobacco smokers. Approximately 6.6 percent of individuals will develop lung cancer during their lifetime. It is the leading cause of cancer deaths, accounting f... | 148 |
How to diagnose MTHFR gene mutation ? | Yes. Genetic testing is available for MTHFR gene mutations. This testing can be used in people with suspected homocystinuria or to determine the cause of elevated homocysteine levels in the blood. Genetic testing for C677T and A1286C may be indicated in a person with elevated homocysteine levels and one or more of the ... | 149 |
Are specific haplotypes of the RET proto-oncogene over-represented in patients with sporadic papillary thyroid carcinoma? | Our data suggest that some variants of RET and some specific haplotypes may act as low penetrance alleles in the predisposition to PTC. | 150 |
Are adult attachment insecurities associated with obsessive compulsive disorder? | Addressing attachment anxiety in individuals presenting with OCD may be important for enhancing therapeutic outcomes. However, findings are based on cross-sectional data that preclude conclusions relating to causal influence. | 151 |
Is antinociceptive response to nitrous oxide mediated by supraspinal opiate and spinal alpha 2 adrenergic receptors in the rat? | These data suggest that both supraspinal opiate and spinal alpha 2 adrenoceptors play a mediating role in the antinociceptive response to N2O in rats. A possible mechanism may involve a descending inhibitory noradrenergic pathway that may be activated by opiate receptors in the periaqueductal gray region of the brain s... | 152 |
Is congenital cataracts, facial dysmorphism, and neuropathy inherited ? | This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. | 153 |
Do mothers with positive or negative depression screens evaluate a maternal resource guide? | Mothers with PDS were more likely to report that the maternal resource guide would be personally helpful compared with mothers with NDS. | 154 |
Is precise histological evaluation of liver biopsy specimen indispensable for diagnosis and treatment of acute-onset autoimmune hepatitis? | Histological examination of the liver is necessary for early diagnosis of acute-onset AIH. Moreover, we should evaluate liver biopsy specimens precisely and should be ready for a timely initiation of corticosteroid therapy to improve the prognosis. | 155 |
Is tai Chi Chuan training associated with enhanced endothelium-dependent dilation in skin vasculature of healthy older men? | Regular practice of TCC is associated with enhanced endothelium-dependent dilation in skin vasculature of older individuals. Moreover, TCC training may delay the age-related decline of venous compliance and hyperemic arterial response. | 156 |
Does association study suggest opposite effects of polymorphisms within IL8 on bronchial asthma and respiratory syncytial virus bronchiolitis? | This is the first study to describe association of IL-8 with asthma and a significant inverse distribution of the polymorphisms in juvenile idiopathic arthritis. In addition, the results of this study might suggest that RSV bronchiolitis and bronchial asthma have at least some different genetic factors. | 157 |
How many people are affected by Moebius syndrome ? | The exact incidence of Moebius syndrome is unknown. Researchers estimate that the condition affects 1 in 50,000 to 1 in 500,000 newborns. | 158 |
Does pirfenidone protect endotoxin-induced liver injury after hepatic ischemia in rats? | These results indicate that PFD prevents endotoxin-induced liver injury after hepatic ischemia-reperfusion, in part through the decrease of neutrophil infiltration to the liver. | 159 |
Who is at risk for Gestational Trophoblastic Disease? ? | Age and a previous molar pregnancy affect the risk of GTD. Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer. Talk to your doctor if you think you may be at risk. ... | 160 |
How many people are affected by X-linked lissencephaly with abnormal genitalia ? | The incidence of XLAG is unknown; approximately 30 affected families have been described in the medical literature. | 161 |
What are the symptoms of Pulmonary venous return anomaly ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Pulmonary venous return anomaly. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these m... | 162 |
What are the treatments for aspartylglucosaminuria ? | These resources address the diagnosis or management of aspartylglucosaminuria: - Genetic Testing Registry: Aspartylglycosaminuria These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Ge... | 163 |
How to diagnose Imerslund-Grasbeck syndrome ? | The diagnosis of Imerslund-Grasbeck syndrome (IGS) is made after a series of tests are performed. Cobalamin deficiency is typically detected first, followed by showing that cobalamin is poorly absorbed (the main cause of cobalamin deficiency). Other known causes of vitamin B12 malabsorption must then be ruled out. Last... | 164 |
What are the genetic changes related to 1p36 deletion syndrome ? | 1p36 deletion syndrome is caused by a deletion of genetic material from a specific region in the short (p) arm of chromosome 1. The signs and symptoms of 1p36 deletion syndrome are probably related to the loss of multiple genes in this region. The size of the deletion varies among affected individuals. | 165 |
Does toll-like receptor 3 mediate PROMININ-1 expressing cell expansion in biliary atresia via Transforming Growth Factor-Beta? | TLR3 activation induces myofibroblastic differentiation of PROM1+ HPC in part via TGFβ pathway activation to promote BA-associated biliary fibrosis. | 166 |
Is Tracheoesophageal fistula inherited ? | In most cases, tracheoesophageal fistula (TEF) is not inherited and there is only one affected person in a family. When TEF is isolated (i.e. does not occur with any other abnormalities), it is considered a multifactorial condition (caused by a combination of various genetic and environmental factors). However, in most... | 167 |
What are the symptoms of Choroideremia ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Choroideremia. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Sign... | 168 |
What are the symptoms of Dry Eye ? | Dry eye symptoms may include any of the following. - stinging or burning of the eye - a sandy or gritty feeling as if something is in the eye - episodes of excess tears following very dry eye periods - a stringy discharge from the eye - pain and redness of the eye - episodes of blurred vision - heavy eyelids... | 169 |
What is (are) guanidinoacetate methyltransferase deficiency ? | Guanidinoacetate methyltransferase deficiency is an inherited disorder that primarily affects the brain and muscles. Without early treatment, people with this disorder have neurological problems that are usually severe. These problems include intellectual disability, speech development limited to a few words, and recur... | 170 |
What is (are) Coma ? | A coma, sometimes also called persistent vegetative state, is a profound or deep state of unconsciousness. Persistent vegetative state is not brain-death. An individual in a state of coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a... | 171 |
Do changes in DNA methylation over the growing season differ between North Carolina farmworkers and non-farmworkers? | We identified considerable changes in DNA methylation at 36 CpG sites over the growing season that differed between farmworkers and non-farmworkers. Dominant pathways included immune-related (HLA) processes, as well as a number of diverse biological systems. Further studies are necessary to determine which exposures or... | 172 |
Is [ The genetic polymorphism of HLA-DQA1 and HLA-DQB1 genes of Chinese Han population in Jiangsu area studied by PCR-sequence-based typing ]? | The distribution of HLA-DQ alleles and haplotypes in Jiangsu Han population shares some genetic characteristics with other population in northern of China, but has its own characteristics. The data will provide useful information for anthropology, organ transplantation and disease association studies. | 173 |
Does elevated serum thymidine kinase 1 predict risk of pre/early cancerous progression? | Serological TK1 may be a reliable marker for risk assessment of pre/early cancerous progression. | 174 |
How many people are affected by multiple endocrine neoplasia ? | Multiple endocrine neoplasia type 1 affects about 1 in 30,000 people; multiple endocrine neoplasia type 2 affects an estimated 1 in 35,000 people. Among the subtypes of type 2, type 2A is the most common form, followed by FMTC. Type 2B is relatively uncommon, accounting for about 5 percent of all cases of type 2. The p... | 175 |
What is (are) methylmalonic acidemia with homocystinuria ? | Methylmalonic acidemia with homocystinuria is an inherited disorder in which the body is unable to properly process protein building blocks (amino acids), certain fats (lipids), and a waxy fat-like substance called cholesterol. Individuals with this disorder have a combination of features from two separate conditions, ... | 176 |
How to diagnose Childhood Interstitial Lung Disease ? | Doctors diagnose childhood interstitial lung disease (chILD) based on a child's medical and family histories and the results from tests and procedures. To diagnose chILD, doctors may first need to rule out other diseases as the cause of a child's symptoms.
Early diagnosis of chILD may help doctors stop... | 177 |
Who is at risk for Pyelonephritis: Kidney Infection? ? | People most at risk for pyelonephritis are those who have a bladder infection and those with a structural, or anatomic, problem in the urinary tract. Urine normally flows only in one directionfrom the kidneys to the bladder. However, the flow of urine may be blocked in people with a structural defect of the urinary tra... | 178 |
What causes What I need to know about Erectile Dysfunction ? | Having ED can cause you to feel depressed or anxious. ED may also cause low self-esteem. When you have ED, you may not have a satisfying sex life. You may not feel as close with your sexual partner, which may strain your relationship.
See Your Doctor if You Have Erectile Dysfunction, ... | 179 |
What are the treatments for Crigler Najjar syndrome, type 2 ? | Treatment for Crigler Najjar syndrome, type 2 is based on trying to reduce bilirubin levels. As a result it is commonly treated with aggressive phototherapy and phenobarbitol. For severe disease, calcium gluconate, intravenous fluids, and albumin may be recommended. Severely affected patients have been treated with pla... | 180 |
What is (are) Deep Vein Thrombosis ? | Deep vein thrombosis, or DVT, is a blood clot that forms in a vein deep in the body. Most deep vein clots occur in the lower leg or thigh. If the vein swells, the condition is called thrombophlebitis. A deep vein thrombosis can break loose and cause a serious problem in the lung, called a pulmonary embolism. Sitting... | 181 |
What is (are) Camurati-Engelmann disease ? | Camurati-Engelmann disease is a genetic condition that mainly affects the bones. People with this disease have increased bone density, particularly affecting the long bones of the arms and legs. In some cases, the skull and hip bones are also affected. The thickened bones can lead to pain in the arms and legs, a waddli... | 182 |
What are the treatments for Li-Fraumeni syndrome ? | These resources address the diagnosis or management of Li-Fraumeni syndrome: - Gene Review: Gene Review: Li-Fraumeni Syndrome - Genetic Testing Registry: Li-Fraumeni syndrome - Genetic Testing Registry: Li-Fraumeni syndrome 1 - Genetic Testing Registry: Li-Fraumeni syndrome 2 - MedlinePlus Encyclopedia: Cancer - ... | 183 |
Do exosomes induce and reverse monocrotaline-induced pulmonary hypertension in mice? | These findings suggest that circulating or MSC-EXOs may modulate pulmonary hypertensive effects based on their miR cargo. The ability of MSC-EXOs to reverse MCT-PH offers a promising potential target for new PAH therapies. | 184 |
Is proinflammatory genotype of interleukin-1 and interleukin-1 receptor antagonist associated with ESRD in proteinase 3-ANCA vasculitis patients? | Patients with a renal manifestation of PR3-ANCA vasculitis have an increased risk for developing end-stage renal disease when carrying the proinflammatory IL-1beta/IL-1ra genotype. Anti-inflammatory therapy specifically antagonizing the proinflammatory effect of IL-1beta may be a promising treatment for patients with W... | 185 |
Is a 40-50kDa Glycoprotein Associated with Mucus Identified as α-1-Acid Glycoprotein in Carcinoma of the Stomach? | AGP levels are increased in gastric tissue and in the plasma of those with carcinoma of the stomach. | 186 |
What are the treatments for Hypochondroplasia ? | The evaluation of children with hypochondroplasia usually does not differ significantly from the evaluation of children with normal stature, except for genetic counseling issues (such as risk of recurrence) and dealing with parental concerns about short stature. Management of short stature may be influenced by the conc... | 187 |
What is (are) Protein C deficiency ? | Protein C deficiency is a disorder that increases a person's risk to develop abnormal blood clots. The condition can be mild or severe. People with mild protein C deficiency are at risk for a type of clot called deep vein thrombosis (DVT). A DVT can travel through the bloodstream and become stuck in the lung, which can... | 188 |
Is exposure to inhibitors of the renin-angiotensin system a major independent risk factor for acute renal failure induced by sucrose-containing intravenous immunoglobulins : a case-control study? | Temporary interruption of ACE-I and ARA may be considered at the time of IVIg infusion. | 189 |
What are the symptoms of MYH7-related scapuloperoneal myopathy ? | The Human Phenotype Ontology provides the following list of signs and symptoms for MYH7-related scapuloperoneal myopathy. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for t... | 190 |
What are the symptoms of Crandall syndrome ? | The Human Phenotype Ontology provides the following list of signs and symptoms for Crandall syndrome. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. ... | 191 |
Do dispositional optimism and thoughts of well-being determine sensitivity to an experimental pain task? | Dispositional optimism is associated with reduced pain for healthy adults encountering a brief pain stimulus. This relationship is eliminated, however, when individuals are primed with thoughts of health and well-being. The results are interpreted as evidence for the use of differential coping strategies by optimists i... | 192 |
Does the ginger component 6-shogaol prevent TNF-α-induced barrier loss via inhibition of PI3K/Akt and NF-κB signaling? | 6-SG has barrier-protective effects by affecting TNF-α-induced claudin-2 upregulation and claudin-1 disassembly via inhibition of phoshatidylinositol-3-kinase/Akt and nuclear factor kappa light chain enhancer of activated B-cell signaling. Therefore, 6-SG-containing food might be beneficial for barrier preservation dur... | 193 |
Is high density of peritumoral lymphatic vessels a potential prognostic marker of endometrial carcinoma : a clinical immunohistochemical method study? | P-LVD may serve as a prognostic factor for endometrial carcinoma. The peritumoral lymphatics might play an important role in lymphatic vessel metastasis. | 194 |
Are ninety-day mortality and major complications affected by use of lung allocation score? | Implementation of the LAS system has not been associated with an increase in early mortality, immediate PGD or major complications. | 195 |
what research (or clinical trials) is being done for Ovarian Epithelial, Fallopian Tube, and Primary Peritoneal Cancer ? | New types of treatment are being tested in clinical trials.
This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website. Radiation therapy Radiat... | 196 |
Is Laing distal myopathy inherited ? | This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In most cases, an affected person inherits the mutation from one affected parent. A small percentage of cases result from new mutations in the gene. These cases occur... | 197 |
Do control of methicillin-resistant Staphylococcus aureus in a pediatric burn unit? | An MRSA control program including surveillance culturing, clinician feedback, flexible, site-specific isolation, and a list of known carriers is associated with a low rate of nosocomial MRSA in a pediatric burn unit. | 198 |
What are the treatments for familial dilated cardiomyopathy ? | - Seattle Children's Hospital: Cardiomyopathy Treatment Options - The Sarcomeric Human Cardiomyopathies Registry (ShaRe) These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Cou... | 199 |
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