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{"en": "Pediatric liver tumors are relatively rare, but thorough knowledge of their imaging features is still important. Frequency and imaging features of benign and malignant liver masses during childhood and adolescence. Discussion of relevant original articles, review manuscripts and expert recommendations concernin... |
{"en": "Imaging plays a major role to differentiate interstitial edematous from necrotic pancreatitis and to describe relevant local complications for proper patient management and decision-making in acute pancreatitis. The revised Atlanta classification 2012 of acute pancreatitis divides patients into mild, moderately... |
{"en": "In implant surgery for erectile dysfunction and urinary incontinence, adequate patient selection is essential for postoperative therapy success. Several scientific studies report patient satisfaction rates for penile implants and artificial urinary sphincter implantation of over 90%. Nevertheless, studies also ... |
{"en": "Aniseikonia as one of the major risk factors for asthenopic problems is mostly overlooked in modern cataract surgery. The purpose of this study was to develop a simple calculation scheme for clinicians to predict the object to image magnification in a pseudophakic eye with biometric data. The calculation scheme... |
{"en": "The treatment of inguinal hernias with open and minimally invasive procedures has reached a high standard in terms of outcome over the past 30 years. However, there is still need for further improvement, mainly in terms of reduction of postoperative seroma, chronic pain, and recurrence. This video article prese... |
{"en": "Osteoprotective medications are a key element not only in the management of bone metastases of castration-resistant prostate cancer (mCRPC) but also of hormone-sensitive prostate cancer (mHSPC). Additionally, osteoprotective drugs can prevent androgen deprivation-induced bone loss. The aim of this study was to ... |
{"en": "The use of combined hormonal contraceptives (CHC) is a well-established risk factor for venous thromboembolism (VTE). The VTE risk depends on the specific combination of oestrogen and gestagen components. Progestin-only contraceptives with the exception of depot medroxyprogesterone acetate are not associated wi... |
{"en": "With the increasing prevalence of continuous glucose monitoring (CGM) systems, time in range (TIR) is gaining importance as a parameter for optimization of glycemic control in patients with type 1 diabetes mellitus. Recent studies showed improved prevention of cardiovascular events and pregnancy complications i... |
{"en": "Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder arising due to mutation in alpha1-antitrypsin (AAT). AAT mutations interfere with the AAT production/secretion, cause decreased AAT serum levels and accumulation of AAT in the liver. The excess AAT leads to a proteotoxic liver disease, while the lack o... |
{"en": "Treating sleep disorders is a challenge in individuals with dementia. A precondition for treatment success is thorough diagnostics of sleep disorders. Sleep diaries and observational questionnairs represent important diagnostic tools. In addition to general treatment strategies including optimal treatment of co... |
{"en": "The risk of malignant lymphomas is markedly increased in HIV-infected persons even in the era of effective combination antiretroviral therapy. Major risk factors are the depth of CD4-cell nadir and HIV viremia. R-CHOP remains treatment of choice for diffuse large B-cell lymphoma. In HIV-Burkitt lymphoma CODOX-M... |
{"en": "Lyme borreliosis is a tick-borne infectious disease caused by the spirochete bacterium Borrelia burgdorferi sensu lato. Lyme borreliosis is the most frequent zoonosis in Germany.Most cases show dermatological manifestations, like erythema migrans, followed by infections of the nervous system. Cerebrospinal flui... |
{"en": "Cardiac arrest is one of the most dramatic medical emergencies. The occurence of cardiac arrest in hospitalized patients, the so called in-hospital cardiac arrest, is common and associated with high mortality. However, in-hospital cardiac arrest has received quite little attention compared to cardiac arrest occ... |
{"en": "Psychocardiological research has contributed a better understanding of mental health, psychosocial factors and quality of life of in patients with cardiovascular diseases. In this update of psychocardiology in 2021, stressful experiences in childhood and adolescence are found to increase the risk of type II dia... |
{"en": "Resistant hypertension (RH) is defined in patients who do not meet their blood pressure targets despite the daily intake of three antihypertensive drugs in maximally tolerated dosages. This triple treatment should comprise (1) an angiotensin-converting enzyme inhibitor (ACE-I) or angiotensin receptor blocker (A... |
{"en": "In hospital, effective smoking cessation can be organized through counselling, pharmacological aids and, above all, continuous care in outpatient structures following discharge. Pharmacological treatment has proven to be effective and safe with nicotine replacement therapy as well as varenicline. Counselling pl... |
{"en": "Lung involvement is one of the most frequent organ manifestation in rheumatic diseases (CTD-ILD). Especially patients with rheumatoid arthritis, systemic sclerosis, and idiopathic inflammatory myopathies are affected. Interstitial lung diseases (ILD) are still associated with significant morbidity and mortality... |
{"en": "In a 67-year-old female patient with upper abdominal pain, computed tomography showed a partly calcified swelling of the pancreatic head and wall thickening of the duodenum. Inpatient physical examination findings were normal. Laboratory showed increased pancreatic enzymes (amylase 210 U/l [Standard range: 28-1... |
{"en": "Chronic pain is a worldwide problem of healthcare along with social and economic factors. The Center for Pain Medicine (CPM) Nottwil offers individualized, interdisciplinary, multimodal pain rehabilitation based on the biopsychosocial approach. The aim of this study was to obtain a real-life analysis of chronic... |
{"en": "Nonopioid analgesics are frequently used for perioperative analgesia; however, insufficient research is available on several practical issues. Often hospitals have no strategy for how to proceed, e.g., for informing patients or for the timing of perioperative administration of nonopioid analgesics. An expert pa... |
{"en": "This study aimed to understand the molecular mechanism underlying the therapeutic effect of Qi Ling (QL) against androgen-independent prostate cancer. The relative expression of TRIM66 in prostate tumor was interrogated by microarray. Real-time polymerase chain reaction and Western blotting were performed to de... |
{"en": "As a result of digitalization, the internet embodies the essential information medium. Especially, patients with sudden sensorineural hearing loss (SSNHL) require profound education due to unclear scientific evidence. Thus, our study investigated a German-language internet search about SSNHL. The first 30 Googl... |
{"en": "Resources for the rapid and comprehensive availability of reliable diagnostic tests were an important prerequisite for the detection and management of the pandemic triggered by the coronavirus disease 2019 (COVID-19). The capacity for the diagnostic tests had to be rapidly planned and established in early 2020 ... |
{"en": "Description of a reproducible surgical technique for single-bundle anterolateral reconstruction of the posterior cruciate ligament (PCL) based on a septum-sparing approach. This technique is less traumatic than the trans-septum approach. The article illustrates surgical steps to simplify the technical aspects o... |
{"en": "Anatomical reduction of dislocated fractures using an angle-stable hook plate. Surgical revision of symptomatic nonunions with the aim of bone regeneration. Dislocated fractures of the ulnar styloid process with involvement of the ulnar fovea. Combined fractures with instability of the distal radioulnar joint a... |
{"en": "Treatment of isolated retropatellar cartilage defects using current gel-type regenerative methods requires settlement of the gel to the underlying subchondral bone under gravity; thus, prone positioned arthroscopy is used. Isolated retropatellar contained cartilage defect size >2.5 cm<sup>2</sup>. Age <40 years... |
{"en": "The COVID-19 pandemic requires extensive health protection interventions in order to prevent infections in the long-term care setting. These interventions impact residents' lives, including an increase in depressive symptoms and other negative concomitants. The study aimed to explore the experiences and perspec... |
{"en": "The SARS-CoV‑2 pandemic has affected the health and practice of otorhinolaryngologists (ORLs) for over 1 year. Follow-up data of a national survey with German ORLs were evaluated regarding differences between the two waves of the pandemic. As in the initial survey, German ORLs were addressed via e‑mail through ... |
{"en": "Atrial fibrillation (AF) will become one of the biggest challenges in cardiovascular medicine in the near future. Attempting an improvement in future patient care calls explicitly for the screening of subclinical AF. Digital health solutions implementing communication technologies for the collection and analysi... |
{"en": "Medical errors are comprised of various problems. Influencing factors include the diseases and procedures involved, the types of errors and the consequential harms of the respective treatment processes. Their contribution is determined for the first time in an extended systematic analysis of errors ascertained ... |
{"en": "Survey by the commission for cross-sectoral ophthalmology, as a joint commission of the German Ophthalmological Society (DOG) and the Professional Association of German Ophthalmologists (BVA) on the effects of the SARS-CoV‑2 pandemic on ophthalmological patient care in Germany. Online-based survey. A total of 1... |
{"en": "Pars plana vitrectomy (ppV) combined with silicone oil tamponade is a standard technique in the treatment of complicated retinal detachment. There are still recurrent cases of retinal detachment after silicone oil removal or redetachment with in situ oil tamponade. The aim was to identify possible risk factors ... |
{"en": "In Germany, 10,000 cases of spontaneous pneumothorax are treated inpatient every year. The German Society for Thoracic Surgery (DGT), in co-operation with the German Society for Pulmonology (DGP), the German Radiological Society (DRG) and the German Society of Internal Medicine (DGIM) has developed an S3 guidel... |
{"en": "We report the case of a 29-year-old patient who presented in the emergency room with severe abdominal pain. After initially inconspicuous medical history and laboratory evaluation, repeated focused history taking led to the correct diagnosis: a paintball projectile had left its mark. The patient had suffered a ... |
{"en": "CME: Jet Lag Jetlag Abstract. Crossing several time zones by air travel leads to a temporary desynchronization of the internal clock with the external light/dark cycle. In the following jet lag occurs typically including difficulties falling asleep or waking up early as well as day-time sleepiness and significa... |
{"en": "Modern Management of Pituitary Adenomas - Current State of Diagnosis, Treatment and Follow-Up Abstract. Pituitary adenomas (PA) are benign neoplasms originating from parenchymal cells of the anterior pituitary. Tumor mass effect can cause headaches, visual deficits by compression of the optic chiasm, and partia... |
{"en": "Perspectives for the Electroencephalogram in Psychiatry Abstract. The electroencephalogram (EEG) is a non-invasive and cost-effective method to monitor spontaneous neuronal activity over time. Pathologies in EEG recordings indicate with high sensitivity but low specificity abnormal functional brain states. The ... |
{"en": "The Influence of Protein on the Prevention of Fragility Fractures Among Senior Adults Abstract. The aim of this review article is to discuss protein intake in senior adults at risk for fragility fractures as a modifiable factor for fracture prevention. Proteins are building blocks of the bone matrix and the mus... |
{"en": "In open wedge osteotomies of the distal radius, bone grafts increase initial stability and enhance bone formation but are frequently associated with complaints and complications at the donor site. Previous studies have suggested that bone grafting may probably be unnecessary. Between 2013 and 2016, 19 patients ... |
{"en": "Because of its form, size and position, the scaphoid is known to be the foundation stone of the carpus, with an exceptionally important biomechanical function. Therefore evaluation of fracture morphology is essential. Experts already agree that computed tomography (CT scan) in the long axis of the scaphoid is t... |
{"en": "Due to the functional coupling of adjacent finger joints and the quadriga effect of the flexor digitorum profundus an influence of the grip pattern of the hand after fusion of a distal interphalangeal joint (DIPJ) is assumed. Two patients with DIPJ II- fusion and 8 patients with DIPJ III- fusion due to a posttr... |
{"en": "Mixed martial arts (MMA) is a combination of multiple combat sports. Acute injuries in MMA are well known and have been broadly described. However, there is little knowledge about degenerative changes in the musculoskeletal system. The aim of this study was to investigate the impact of techniques used in MMA on... |
{"en": "We report on the outcomes of treatment for severe pain associated with long-standing, refractory CRPS in 10 female patients by continuous brachial plexus analgesia. The duration of the disease prior to treatment was 3.5 years on average, and mean baseline pain intensity was 8.3 on a numeric analogue scale (NRS)... |
{"en": "This study was performed to determine whether between 2015 and 2017 there has been a change in the preferred method of treatment of Dupuytren disease by German hand surgeons, especially with respect to percutaneous needle fasciotomy. In 2015 and 2017, 530 members of the German Society for Surgery of the Hand we... |
{"en": "We present two cases of chronic palmar luxation of the distal ulna which entails the development of complex regional pain syndrome (CRPS). Both cases have been finally treated with a hemiresection-interposition-arthroplasty of the distal radioulnar joint with perioperatively applied regional nerve block and i. ... |
{"en": "Dynamic splinting is a well-known method for maintaining finger movement after ruptures of the extensor tendons. We describe a simple, inexpensive and easy-to-construct modification of a dynamic splint, called the 'Sparti' splint, suitable for a six-week period of rehabilitation of injured extensor tendons in z... |
{"en": "Behçet's disease is a multi-system disease with inflammatory infestations, in particular of the small and middle arteries and veins. Histologically, the disease presents with the image of leukocytoclastic vasculitis. The etiology of Behçet disease is unknown, but genetic factors are discussed of playing a role ... |
{"en": "There has been a steady increase in the interest in regional health analysis. This is reflected both in national and international publications of health atlases. The aim of this study was to examine the current national health atlases, as instruments of communication, in a comparative analysis. First, a system... |
{"en": "In February 2013, the law on the improvement of the rights of patients enacted a whole series of legal regulations for different areas of health care. In terms of physician liability, the Patient Rights Act and the introduction of sections 630a-h in the Civil Code (BGB) brought a transparency-oriented represent... |
{"en": "Recent registry data predict a significant increase in revision surgery in TKA, which is often associated with severe bony defects. Stable and correct implant fixation remains a challenge. The prerequisite for long-term and reproducible results is the selection of the correct reconstruction and fixation strateg... |
{"en": "Lower urinary tract fistulas are currently a rather rare, but severe condition associated with considerable morbidity. Treatment is challenging, especially in fistulas caused by pelvic malignancy or radiation therapy. Surgical treatment attempts fail in a considerable number of patients, especially in those wit... |
{"en": "Transjugular intrahepatic portosystemic shunt (TIPS) is a non-selective portosystemic shunt created using endovascular techniques. During recent years technical improvements and new insights into pathophysiology have modified indications for TIPS placement. In this article we therefore want to discuss current k... |
{"en": "The aim of this study was to investigate the diagnostic value of cardiac magnetic resonance (CMR)-derived strain parameters in patients with sarcoidosis, and to compare results to standard CMR markers of sarcoidosis (edema/T2 ratio, early gadolinium enhancement, late gadolinium enhancement) for prediction of di... |
{"en": "To investigate the degree of impairment in left (LV) and right ventricular (RV) myocardial strain parameters over the course of acute myocarditis and to evaluate its value for the prediction of functional recovery upon follow-up. 69 patients with acute myocarditis underwent cardiac magnetic resonance imaging du... |
{"en": "Acute portal vein thrombosis is a potentially fatal condition. In symptomatic patients not responding to systemic anticoagulation, interventional procedures have emerged as an alternative to surgery. This study sought to retrospectively evaluate initial results of interventional treatment of acute portal vein t... |
{"en": "Quantitative and qualitative analysis of gadopentetate dimeglumine (GD) versus standard-dose (sGb) and half-dose (hGb) gadobutrol in thoracoabdominal time-resolved contrast-enhanced magnetic resonance angiography (4D-MRA) with dynamic computed tomography (dCT) as the quantitative reference in minipigs. 7 anesth... |
{"en": "To directly compare different methods proposed for enhanced conspicuity and discriminability of prostate cancer on diffusion-weighted imaging (DWI) and to compare the results to original DWI images and conventional apparent diffusion coefficient (ADC) maps. Clinical routine prostate DWI datasets (b = 0, 50, 800... |
{"en": "Psychotherapeutic resources are limited, leading to prolonged waiting periods prior to outpatient psychotherapy. Low-intensity interventions have the potential to bridge such treatment gaps. This systematic review aims to identify interventions targeting depressive symptoms implemented prior to outpatient psych... |
{"en": "Damage to the hand caused by vibration has been observed with a range of trades and professions and in connection with various types of sport. Osseous, neurogenic and vascular lesions can lead to chronic ailments and permanent functional impairment. Hand-arm vibration syndrome (HAVS) and hypothenar/thenar hamme... |
{"en": "Active fall prevention requires analysis of the mechanisms provoking falls and the subsequent initiation of appropriate counteracting measures. This is crucial for the quality management of all rehabilitation programs. There is primary and secondary fall prevention. For the latter, specific and individualized m... |
{"en": "Incidence and survival rates in patients with cancer are rising as well as the potential rehabilitation needs. In contrast, the numbers of rehabilitation treatments after cancer are decreasing. The reasons are not yet completely understood. A written survey with patients of three cancer indications breast cance... |
{"en": "We investigated the prevalence of multidrug resistant pathogens in patients of oncologic and cardiologic rehabilitation units with 155 oncologic and 157 cardiologic patients undergoing microbiologic screening. It was found that 4.5% of oncologic as well as cardiologic patients were colonized with multidrug resi... |
{"en": "Over the last years the prevalence of diabetes mellitus (DM) has risen. Due to the disease pattern an increasing importance of rehabilitation services is assumed as well. This article contributs to the debate by analyising the use of medical rehabilitations from 2006 to 2013. The secondary data analysis is base... |
{"en": "Most disorders in neurological and neurosurgical early rehabilitation (NNER) are associated with an increased pneumonia risk. Respiratory therapy aims to prevent respiratory complications. However, there are no studies showing an effect of respiratory muscle training on the incidence of pneumonia in NNER. The s... |
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